CN105535377A - Compound traditional Chinese medicine spray for treating cervical spondylosis - Google Patents

Compound traditional Chinese medicine spray for treating cervical spondylosis Download PDF

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Publication number
CN105535377A
CN105535377A CN201610001054.9A CN201610001054A CN105535377A CN 105535377 A CN105535377 A CN 105535377A CN 201610001054 A CN201610001054 A CN 201610001054A CN 105535377 A CN105535377 A CN 105535377A
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spray
chinese medicine
cervical spondylosis
chinese
described spray
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裘绍雄
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486—Millettia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to compound traditional Chinese medicine spray. The spray has the functions of promoting the circulation of qi, activating blood, removing blood stasis and dredging collaterals, and is mainly used for treating cervical spondylosis. The spray is prepared from 20wt% of rhizome corydalis, 15wt% of pseudo-ginseng, 7wt% of Radix Salviae Miltiorrhizae, 8wt% of Crocus sativus, 3wt% of Antiaris toxicaria (Pers.) Lesch., 17wt% of Shortstalk Monkshood roots, 10wt% of Rhizoma Paridis Chinensis, 10wt% of suberect spatholobus stems and 10wt% of fructus liquidambaris.

Description

A kind of herbal mixture spray for the treatment of cervical spondylosis
Technical field
The present invention relates to a kind of herbal mixture spray, described spray have circulation of qi promoting, invigorate blood circulation, the function of dispel silt, dredging collateral, be mainly used in the treatment of cervical spondylosis.
Background technology
Cervical spondylosis is a kind of commonly encountered diseases and frequently-occurring disease, is the clinical manifestation that intervertebral disc of cervical vertebra degenerative change and secondary pathological change thereof involve its structures surrounding (nerve root, spinal cord, vertebral artery, sympathetic nerve etc.) and appearance.The degenerative change of cervical vertebra is only had then to be called cervical vertebra degenerative change without clinical manifestation person.Increase along with the modern times are engaged in the working method crowd that bows, as widely using of computer, the chance that people bend neck constantly increases, and cause the prevalence of cervical spondylosis constantly to rise, and age of onset has the trend of rejuvenation.
According to the difference of affected tissue and structure, cervical spondylosis is divided into: neck type (also known as soft tissue type), spondylotic radiculopathy, myeloid form, sympathetic type, vertebral artery type, its alloytype (at present mainly finger esophagus compressive).If two or more type exists simultaneously, be called " mixed type ".
The clinical manifestation of cervical spondylosis, can have corresponding feature because of the difference of typing, its modal clinical manifestation has: dizzy or dizzy, headache or migraine, head are heavy, occipitalia pain, stiffness of the neck, numb limbs and tense tendons, the dyskinesia etc.
The treatment of cervical spondylosis have operation and No operation point, it is reported, the Patients with Cervical Spondylopathy of 90% ~ 95% can obtain through non-operative treatment to be alleviated or fully recovers.Non-operative treatment mainly adopts the composite treatments such as the traditional Chinese medical science, doctor trained in Western medicine, the combination of Chinese and Western medicine and rehabilitation at present.
Chinese traditional treatment means comprise: oral medicinal herb, external therapy of Chinese herb (rising medicine, the drug of topical application, spray medicine etc.), massage, acupuncture, thorn blood, cup etc.Thorn blood, cup or thorn blood, cup in conjunction with Chinese medicine spray medicine, have letter, just, test, honest and clean characteristic, be development in recent years a kind of comprehensive treatment faster, wherein, whether combining spray medicine and the prescription of Chinese medicine is sprayed in institute, is the key factor of its curative effect quality of decision.
Summary of the invention
The invention provides a kind of herbal mixture spray, described spray have circulation of qi promoting, invigorate blood circulation, the function of dispel silt, dredging collateral, be mainly used in the treatment of cervical spondylosis.
If not particularly point out, the Material Percentage of spray of the present invention all refers to percentage by weight.
Chinese medicinal components and the ratio thereof of described spray are as follows: Rhizoma Corydalis 20wt%, Radix Notoginseng 15wt%, Radix Salviae Miltiorrhizae 7wt%, Stigma Croci 8wt%, crossbow bolt medicine 3wt%, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 17wt%, Rhizoma Paridis 10wt%, Caulis Spatholobi 10wt%, Fructus Liquidambaris 10wt%.
Above-mentioned all Chinese medicinal components, all can commercially conveniently buy, and wherein, crossbow bolt medicine mainly originates from Miao ethnic group of Lincang City of Yunnan Province residential area.
The preparation method of described spray: by weight percentage, above-mentioned all Chinese drug-treated group are split in pottery or rustless steel container, add the edible distillate spirit that alcoholic strength is 48 ~ 53%, Chinese liquor addition is 25 ~ 30 times of Chinese medicine weight summation, the abundant submergence of all Chinese medicine, add a cover closed, soak 48 ~ 72 hours, filter through 800 ~ 1000 mesh filter screen filtering techniques well known in the art, obtain clarification medicinal liquid, fill, to in the container of shower nozzle, packs.
The main physical and chemical index of described spray: amber transparent liquid; There is characteristic odor; PH value 6.5 ± 0.2.
The sanitary index of described spray: total number of bacteria≤10cfu/g, total number of fungi≤10cfu/g.
Confirm through animal experiment, described spray is non-stimulated to intact skin, can not cause skin allergic reaction.
The range of application of described spray: combine thorn blood, cupping therapy, for the treatment of cervical spondylosis.
The using method of described spray: at enforcement thorn blood, before cupping for treatment, on rear side of the cervical region of patient or occipitalia, spray described spray, fountain height is 0.3 ~ 0.5ml/cm 2(skin area), to spray after spray 1 ~ 2 minute, by method well known in the art, implements thorn blood, cupping for treatment.
The therapeutic effect of described spray: according to the diagnostic criteria of " cervical spondylosis diagnosis and treatment and rehabilitation guide " (Chinese cervical spondylosis Professional Committee works out, 2010 editions), the Patients with Cervical Spondylopathy 200 examples made a definite diagnosis is divided into A, B two groups at random, often organizes each 100 examples.Wherein, what A group patient spinal cord function was evaluated is equally divided into 21 points, and what B group patient spinal cord function was evaluated is equally divided into 20 points.A group is pricker, cup routinely, does not use spray in advance; B group uses spray in advance, then pricker, cup.Treating 1 time every other day, is for 5 times 1 course for the treatment of.After terminating the course for the treatment of, with reference to the efficacy assessment standard (40 point-score) of above-mentioned " cervical spondylosis diagnosis and treatment and rehabilitation guide ", evaluation curative effect: what A group patient spinal cord function was evaluated is equally divided into 29, compare with before treatment, mark rises 8 points, mark climbing 38%; What B group patient spinal cord function was evaluated is equally divided into 36 points, and mark rises 16 points, mark climbing 80%.The curative effect of B group is obviously better than A group.
The recipe principle of described spray: the clinical symptoms that cervical spondylosis shows, regardless of its typing, by differential diagnosis in tcm, all has the common pathological characters of qi stagnation blood stasis, and the stagnation of QI and blood stasis can reciprocal causations, and the operation of blood especially depends on the promotion of gas.Spray of the present invention adopts heavy dose of Rhizoma Corydalis, and circulation of qi promoting is broken stagnant, promotes blood; Radix Notoginseng, Radix Salviae Miltiorrhizae, Stigma Croci, crossbow bolt medicine, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Rhizoma Paridis, change silt removing mass; Caulis Spatholobi, Fructus Liquidambaris, meridians dredging.Full side is warm in nature, has circulation of qi promoting, invigorates blood circulation, the function of dispel silt, dredging collateral.
Usefulness of the present invention is:
1, described spray is simple for production, easy to use.
2, sting blood, cup, be combined described spray, for the treatment of cervical spondylosis, there is quick-acting, effective characteristic.
Detailed description of the invention
The preparation of spray described in embodiment 1.
Rhizoma Corydalis 20g, Radix Notoginseng 15g, Radix Salviae Miltiorrhizae 7g, Stigma Croci 8g, crossbow bolt medicine 3g, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 17g, Rhizoma Paridis 10g, Caulis Spatholobi 10g, Fructus Liquidambaris 10g, be placed in ceramic vessel, add the edible distillate spirit that 2500g alcoholic strength is 48%, the abundant submergence of all Chinese medicine, adds a cover closed, soaks 72 hours, filter through 800 mesh filter screen filtering techniques well known in the art, must clarify medicinal liquid, fill, to in the container of shower nozzle, packs.
The preparation of spray described in embodiment 2.
Rhizoma Corydalis 20g, Radix Notoginseng 15g, Radix Salviae Miltiorrhizae 7g, Stigma Croci 8g, crossbow bolt medicine 3g, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 17g, Rhizoma Paridis 10g, Caulis Spatholobi 10g, Fructus Liquidambaris 10g, be placed in ceramic vessel, add the edible distillate spirit that 3000g alcoholic strength is 53%, the abundant submergence of all Chinese medicine, adds a cover closed, soaks 48 hours, filter through 1000 mesh filter screen filtering techniques well known in the art, must clarify medicinal liquid, fill, to in the container of shower nozzle, packs.
Although the present invention has explained detailed description of the invention and has described; but for a person skilled in the art; can make some changes, amendment and modification when not deviating from the spirit and scope of the present invention, but above-mentioned change, amendment and modification all drop within protection scope of the present invention.

Claims (5)

1. the spray be made up of herbal mixture, it is made up of following raw material: Rhizoma Corydalis 20wt%, Radix Notoginseng 15wt%, Radix Salviae Miltiorrhizae 7wt%, Stigma Croci 8wt%, crossbow bolt medicine 3wt%, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 17wt%, Rhizoma Paridis 10wt%, Caulis Spatholobi 10wt%, Fructus Liquidambaris 10wt%.
2. spray according to claim 1, is characterized in that described spray is amber transparent liquid, has characteristic odor, pH value 6.5 ± 0.2.
3. the spray according to any one of claim 1 ~ 2, is characterized in that described spray has circulation of qi promoting, invigorates blood circulation, the function of dispel silt, dredging collateral.
4. the spray according to any one of claims 1 to 3, is characterized in that the treatment of described spray for cervical spondylosis.
5. spray according to claim 1, its preparation method is: by percentage by weight according to claim 1, all Chinese drug-treated group is split in pottery or rustless steel container, adds the edible distillate spirit that alcoholic strength is 48 ~ 53%, Chinese liquor addition is 25 ~ 30 times of Chinese medicine weight summation, the abundant submergence of all Chinese medicine, adds a cover closed, soaks 48 ~ 72 hours, filter through 800 ~ 1000 mesh filter screens, must clarify medicinal liquid, fill, to in the container of shower nozzle, packs.
CN201610001054.9A 2016-01-05 2016-01-05 Compound traditional Chinese medicine spray for treating cervical spondylosis Pending CN105535377A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115645504A (en) * 2022-09-09 2023-01-31 贵州大学 Compound rhizoma corydalis spray and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050054A1 (en) * 1997-05-06 1998-11-12 Muehlbauer Roman Conrad Plant extracts for the treatment of increase bone resorption

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050054A1 (en) * 1997-05-06 1998-11-12 Muehlbauer Roman Conrad Plant extracts for the treatment of increase bone resorption

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张兆旺: "《中药药剂学》", 31 January 2003, 中国中医药出版社 *
旷惠桃等: "《中医本草疗法（珍藏本）超值版》", 31 August 2012, 湖南科学技术出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115645504A (en) * 2022-09-09 2023-01-31 贵州大学 Compound rhizoma corydalis spray and preparation method thereof
CN115645504B (en) * 2022-09-09 2024-03-15 贵州大学 Compound element Hu Penwu agent and preparation method thereof

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Application publication date: 20160504