CN1055011C - Fresh preparation of motherwort and its prepn. method - Google Patents
Fresh preparation of motherwort and its prepn. method Download PDFInfo
- Publication number
- CN1055011C CN1055011C CN97105252A CN97105252A CN1055011C CN 1055011 C CN1055011 C CN 1055011C CN 97105252 A CN97105252 A CN 97105252A CN 97105252 A CN97105252 A CN 97105252A CN 1055011 C CN1055011 C CN 1055011C
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- preparation
- motherwort
- herba leonuri
- fresh
- dextrin
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a fresh preparation of motherwort and a preparation method. Firstly, 100 portions by weight of fresh motherwort are processed by homogenate and centrifugally filtered; 2 to 3.5 portions by weight of dextrin are added to the physic liquor and homogenized; the mixture is sprayed and dried to medicinal powder to obtain a semi-finished product; then, the semi-finished product is made into pills, tablets, granules, capsules and oral medicinal liquid. The officinal preparation of fresh motherwort is a good medicine for promoting uterus involution of postpartum, has the functions of removing blood stasis to promote tissue regeneration and promoting blood flow to regulate menstruation; compared with the ripe dry motherwort preparation, the present invention has good curative effect and safety in use without adverse reaction.
Description
The present invention openly relates to the Chinese medicine preparation preparation method, relates in particular to the preparation method of bright motherwort preparation.
Herba Leonuri records in Chinese Pharmacopoeia, is labiate, and according to the literature, Herba Leonuri has multiple pharmacological effect.Mainly show to the excitation in animal isolated uterine and uterus on the throne with to the effect of cardiovascular system, its main component is stachydrine and leonurine, but because collecting season and storage time is different, its content differs bigger, through to bright, dried Herba Leonuri at different collecting seasons, different storage time Herba Leonuri total alkalis carry out assay, the amount of results sample total alkaloids is between 0.11～2.09%, it is very big that content differs, the matter that flower is gathered in earlier stage is tender, the amount of the aquatic foods product Herba Leonuri total alkaloids that leaf is many is old than matter, and the sample that stem is many is high.Present motherwort formulation adopts dried Herba Leonuri usually.
The preparation method that the purpose of this invention is to provide the bright motherwort preparation of a kind of promoting tissue regeneration by removing blood stasis, promoting blood flow to regulate menstruation.
The present invention takes following measures in order to achieve the above object:
The preparation method of Herba Leonuri pharmaceutical formulation is with flower bright product Herba Leonuri in the early stage homogenate of 100 weight portions, through centrifugal filtration, adds 2～3.5 weight portion dextrin in its medicinal liquid, stirs evenly, and by being spray dried to medicated powder, makes medicament with the pharmaceutical methods of routine again.
Bright motherwort preparation is the good medicine that promotes the involution of uterus in puerperal, and it has the effect of promoting tissue regeneration by removing blood stasis, promoting blood flow to regulate menstruation, and more sophisticated dried motherwort formulation has good curative effect, and safe in utilization, does not see untoward reaction.Observe and find from producing the relevant sign of the involution of uterus, obey bright motherwort preparation after 1 day involution of uterus condition improved obvious, thereby explanation to take as early as possible puerperal so that reach optimum curative effect.
Elaborate below in conjunction with embodiment.
The prepared pharmaceutical formulation of Herba Leonuri pharmaceutical formulation preparation method is pill, tablet, capsule, granule or oral liquid.The dextrin that adds in said medicinal liquid is 2.2～2.8 weight portions.
The rotating speed of centrifuge is 3000～5000 rev/mins, is generally 3000～4000 rev/mins, and the spray dryer inlet temperature is 190～220 ℃, is generally 195～210 ℃, and outlet temperature is 90～110 ℃, is generally 90～95 ℃.
Embodiment:
To spend bright product Herba Leonuri medical herbs 135kg in early stage earlier, homogenate, through centrifugal filtration (rotating speed is 3000 rev/mins), get medicinal liquid 94.5kg, add dextrin 3kg, stir evenly, spray-dried (inlet temperature is 195 ℃, 95 ℃ of outlet temperatures) gets medicated powder 5.6kg, dry granulation (side pressure 3.2kg, rotating speed, 320 rev/mins) the cover capsule is promptly.
Claims (5)
1. the preparation method of a Herba Leonuri pharmaceutical formulation, it is characterized in that it is with flower bright product Herba Leonuri in the early stage homogenate of 100 weight portions, through centrifugal filtration, adds 2～3.5 weight portion dextrin, stirs evenly in its medicinal liquid, by being spray dried to medicated powder, make medicament with the pharmaceutical methods of routine again.
2. the prepared medicament of preparation method of the Herba Leonuri pharmaceutical formulation of a claim 1 is characterized in that said pharmaceutical formulation is pill, tablet, capsule, granule or oral liquid.
3. the preparation method of claim 1, the rotating speed that it is characterized in that centrifuge is 3000～5000 rev/mins, and the spray dryer inlet temperature is 190～220 ℃, and outlet temperature is 90～110 ℃.
4. the preparation method of claim 1 is characterized in that the dextrin that adds is 2.2～2.8 weight portions in said medicinal liquid.
5. the preparation method of claim 3, the rotating speed that it is characterized in that centrifuge is 3000～4000 rev/mins, and the spray dryer inlet temperature is 195～210 ℃, and outlet temperature is 90～95 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97105252A CN1055011C (en) | 1997-07-11 | 1997-07-11 | Fresh preparation of motherwort and its prepn. method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97105252A CN1055011C (en) | 1997-07-11 | 1997-07-11 | Fresh preparation of motherwort and its prepn. method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1205212A CN1205212A (en) | 1999-01-20 |
| CN1055011C true CN1055011C (en) | 2000-08-02 |
Family
ID=5167790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97105252A Expired - Fee Related CN1055011C (en) | 1997-07-11 | 1997-07-11 | Fresh preparation of motherwort and its prepn. method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1055011C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1456257B (en) * | 2003-02-20 | 2010-04-28 | 浙江大德药业集团有限公司 | Fresh motherwort particle preparing method |
-
1997
- 1997-07-11 CN CN97105252A patent/CN1055011C/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 《中药大辞典》第一版 1977.7.31 江苏新医学院编，上海科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1456257B (en) * | 2003-02-20 | 2010-04-28 | 浙江大德药业集团有限公司 | Fresh motherwort particle preparing method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1205212A (en) | 1999-01-20 |
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|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |