CN105496374B - Strengthen computer aided medicine system - Google Patents
Strengthen computer aided medicine system Download PDFInfo
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- CN105496374B CN105496374B CN201610002066.3A CN201610002066A CN105496374B CN 105496374 B CN105496374 B CN 105496374B CN 201610002066 A CN201610002066 A CN 201610002066A CN 105496374 B CN105496374 B CN 105496374B
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- insulin
- blood sugar
- bluetooth
- concentration
- subsystem
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
Abstract
The present invention relates to a kind of enhancing computer aided medicine system, described accessory system includes Automatic insulin injection subsystem, pulse detection subsystem, blood sugar test subsystem and AVR32 chip, described pulse detection subsystem and described blood sugar test subsystem are respectively used to extract pulse data and the blood glucose level data of tested personnel, described AVR32 chip and described Automatic insulin injection subsystem, described pulse detection subsystem and described blood sugar test subsystem connect respectively, determine whether to send cacosphyxia identification signal based on the pulse data of described pulse detection subsystem, determine whether that controlling described Automatic insulin injection subsystem is the automatic insulin injection of tested personnel based on the blood glucose level data of described blood sugar test subsystem.Pass through the present invention, on the one hand, can automatically detect whether tested personnel has normal pulse information, on the other hand, be capable of the automatic injection of insulin.
Description
Technical field
The present invention relates to assist treatment field, particularly relate to a kind of enhancing computer aided medicine system.
Background technology
Sugar in blood is referred to as blood sugar, is all glucose in most cases.Internal each histocyte
Energy major part needed for Huo Dong is from glucose, so blood sugar preferably must be held in certain level and could tie up
Hold the demand of internal each organ and tissue.
The concentration of the blood sugar in human body is generally controlled in a very narrow scope, and blood sugar is too high or mistake
Low all can affect to people.In order to effectively detect the blood sugar concentration in human body, on the market
Occurring in that multiple blood glucose meter, the especially patient by suffering from hypertension is favored.
But, blood glucose meter of the prior art detection parameter is single, testing mechanism falls behind, and lacks blood sugar
What detection and insulin supplied automatically controls mechanism, and meanwhile, the wireless communication interface being furnished with mates and connects
Connect inefficiency, can not meet the existing requirement of hospital and patient.
To this end, the present invention has built a kind of enhancing computer aided medicine system, will be through structure optimization
High-precision pulse monitoring equipment and blood glucose monitoring device be integrated in a detecting instrument, adopt simultaneously
Bluetooth communication interface after the automatic control mode supplying with blood sugar test and insulin and optimization, be
The use of patient and hospital provides more convenient.
Content of the invention
In order to solve the technical problem that prior art exists, the invention provides a kind of enhancing computer aided manufacturing
Help medical system, pulse detection equipment and blood sugar test equipment are concentrated in a detecting instrument simultaneously
Work, optimizes the structure of existing blood sugar test equipment, improves the precision of blood sugar test, adds meanwhile
Enter insulin pump and insulin supply controlling mechanism, it is achieved automatically controlling of blood sugar concentration, particularly important
, by improving matching mechanisms and the connection mechanism of existing bluetooth communication interface, improve blood sugar instrument
The communication efficiency of wireless connection.
According to an aspect of the present invention, a kind of computer aided medicine system that strengthens is provided, described auxiliary
Auxiliary system include Automatic insulin injection subsystem, pulse detection subsystem, blood sugar test subsystem and
AVR32 chip, described pulse detection subsystem and described blood sugar test subsystem are respectively used to extract quilt
The pulse data of survey personnel and blood glucose level data, described AVR32 chip and described Automatic insulin injection
System, described pulse detection subsystem and described blood sugar test subsystem connect, respectively based on described arteries and veins
Fight detection subsystem pulse data determine whether to send cacosphyxia identification signal, based on described blood sugar
The blood glucose level data of detection subsystem determines whether that it is tested for controlling described Automatic insulin injection subsystem
The automatic insulin injection of personnel.
More specifically, in described enhancing computer aided medicine system, comprising: enzyme electrode sensor,
Including reference electrode, to pole electrode and three electrodes of working electrode, working electrode is fixed with glucose
Oxidizing ferment, wherein, when the tested blood sample of tested personnel is dropped in the test zone of working electrode, work
Make glucose oxidase fixing on electrode and the glucose generation chemical reaction in tested blood sample, work
Response current on electrode is linear with the concentration of glucose in tested blood sample；Amplifying circuit, with
Described enzyme electrode sensor connects, for the response current receiving and amplifying on working electrode；Low pass filtered
Ripple device, is connected with described amplifying circuit, for receiving and filtering the radio-frequency component in response current；MMC
Storage card, is used for storing preset ratio coefficient；First resistance, one end is connected with 5V power supply, another
End is connected with the anode of infrared receiving diode；Second resistance, one end is connected with 5V power supply, another
End is connected with one end of the 3rd resistance；3rd resistance, the other end is grounded, and has and the second resistance phase
Same resistance；First two-way operational amplifier, for producing the reference voltage of 2.5V, its anode and the
The other end of two resistance connects, and one end of negative terminal and the first electric capacity connects, output and infrared emission two
The negative terminal of pole pipe connects, and negative terminal is also connected with the negative terminal of infrared-emitting diode；First electric capacity, another
End ground connection；4th resistance, one end is connected with the negative terminal of infrared-emitting diode；Second two-way computing is put
Big device, the other end of anode and the 4th resistance connects, and negative terminal is connected with the anode of infrared receiving diode,
Output is as pulse voltage；5th resistance, is connected in parallel on the second two-way operational amplifier negative terminal and second
Between two-way operational amplifier output terminal；Second electric capacity, is connected in parallel on the second two-way operational amplifier negative terminal
With second between two-way operational amplifier output terminal；Infrared-emitting diode, is arranged on tested personnel's ear
Capillary position, portion, is used for launching infrared light, the negative terminal of infrared-emitting diode and infrared receiver two
The anode of pole pipe connects；Infrared receiving diode, is arranged on tested personnel ear capillary position,
It is positioned at the relative position of described infrared-emitting diode, be used for receiving transmission tested personnel ear blood capillary
Infrared light after pipe；AVR32 chip, with described low pass filter and described MMC storage card difference
Connect, calculate the blood sugar concentration of tested personnel based on preset ratio coefficient and filtered response current,
Wherein, preset ratio coefficient is for determining the response current on working electrode and the glucose in tested blood sample
The ratio of linear relationship between concentration；Described AVR32 chip also with described second two-way operational amplifier
Output connect obtaining described pulse voltage, and when described pulse voltage default pulse range it
When outer, send cacosphyxia identification signal, when described blood sugar concentration is at default blood sugar upper concentration,
Send blood sugar concentration too high identification signal, when described blood sugar concentration is at default blood sugar least concentration, send out
Go out blood sugar concentration too low identification signal；Insulin storage device, for prestoring the pancreas of preset capacity
Island element；Liquid level detection device, is positioned at described insulin storage device, for real-time detection insulin
Insulin liquid level in storage device, and when insulin liquid level is equal to or less than preset reference liquid level,
Send insufficient insulin alarm signal, described liquid level detection device be also connected with described AVR32 chip with
Described insufficient insulin alarm signal is sent to described AVR32 chip；Insulin drives equipment, with
Described AVR32 chip connects, when receiving described blood sugar concentration too high identification signal, according to described
Blood sugar concentration and the difference of described default blood sugar upper concentration that AVR32 chip forwards determine insulin
Pump drive signal, described insulin pump drives the value of the supply insulin of signal deciding insulin pump
And speed；Insulin pump, connects respectively with described insulin storage device and insulin infusion device,
Equipment is driven to be connected with described insulin, under the control of described insulin driving equipment, by institute
The insulin stated in insulin storage device is expelled in tested personnel's body by insulin infusion device；
Insulin infusion device, detachable is embedded in tested personnel's body, for injecting pancreas to tested personnel
Island element；Serial communication circuit, is positioned between AVR32 chip and Bluetooth matching communication equipment, and being used for will
Described blood sugar concentration and described insufficient insulin alarm signal are sent to Bluetooth matching communication equipment；Bluetooth
Matched communicating devices, for transmitting wirelessly described blood sugar concentration and described insufficient insulin alarm signal
To the target Bluetooth devices connecting；Described Bluetooth matching communication equipment include the first search subset,
Second search subset and coupling connexon equipment；Wherein, the first search subset, dissipates according to bluetooth
Penetrate the micro bluetooth network that MAC Address concentration in net determines that Bluetooth MAC address concentration is the highest as mesh
Mark piconet, a Bluetooth Scatternet is made up of multiple micro bluetooth networks；Second search subset, with
Described first search subset connects, and in described target piconet, finds and exists by signal strength signal intensity ranking
Before, quantity be not more than one or more Bluetooth matching communication equipments of 7 as one or more targets
Bluetooth equipment；Equipment connexon equipment, is connected with described second search subset, starts and described one
Individual or multiple target Bluetooth devices Bluetooth communication connects；Wherein, when described target piconet has letter
Number Bluetooth matching communication equipment quantity for more than or equal to 7 when, the one or more target Bluetooth
The quantity of equipment is 7, when the number of the Bluetooth matching communication equipment having signal in described target piconet
Amount is for during less than 7, and the quantity of the one or more target Bluetooth devices is in described target piconet
There is the quantity of the Bluetooth matching communication equipment of signal；Wherein, described MMC storage card and described AVR32
Chip connects, and prestores described default pulse range, described default blood sugar upper concentration and described
Preset blood sugar least concentration.More specifically, in described enhancing computer aided medicine system: hot
Between emission diode and infrared receiving diode during pulseless, pulse voltage is 2.5V, when infrared
When there is, between emitting diode and infrared receiving diode, the pulse beated, blood vessels make ear's light transmission
Being deteriorated, pulse voltage is more than 2.5V.More specifically, in described enhancing computer aided medicine system:
First two-way operational amplifier and the second two-way operational amplifier are all the two-way operation amplifier of TI company
Device.More specifically, in described enhancing computer aided medicine system: described serial communication circuit is
RS232 serial communication interface.More specifically, in described enhancing computer aided medicine system: institute
State AVR32 chip and send cacosphyxia identification signal, blood sugar too high identification signal or hypoglycemia knowledge
During level signal, being simultaneously emitted by abnormality signal, otherwise, described AVR32 chip is simultaneously emitted by normally
Status signal.
Brief description
Below with reference to accompanying drawing, embodiment of the present invention are described, wherein:
Fig. 1 is the structure square frame of the first embodiment of the enhancing computer aided medicine system of the present invention
Figure.
Reference: 1 Automatic insulin injection subsystem；2 pulse detection subsystems；3 blood sugar inspections
Survey subsystem；4AVR32 chip
Detailed description of the invention
Below with reference to accompanying drawings the embodiment of the enhancing computer aided medicine system of the present invention is entered
Row describes in detail.
Blood sugar, refers to glucose contained in blood.Postdigestive glucose is entered blood by small intestine,
And each cell being transported in body, it is the main energy sources of cell.The blood sugar of normal person is dense
Spend relatively stable, fall within a confirmable blood glucose range.
Blood sugar must keep certain level could maintain the needs of each organ internal and tissue.Blood sugar
Raise after general one to two hours on the feed of concentration, and be preferably minimized at breakfast.Blood sugar concentration is lacked of proper care
Can cause multiple disease, the too high hyperglycaemia of continuation blood sugar concentration and too low hypoglycemia all can give people
Health cause serious impact, and the Persistent hyperglycemia being caused by many reasons will cause glycosuria
Disease, this is also the related the most significant disease of blood sugar concentration.
Prior art exists Medical Instruments of some detection blood sugar, but below these blood glucose meter all exist
Defect: (1) detection pattern is single, can only detect blood sugar concentration；(2) testing mechanism falls behind, knot
Structure redundancy is too high, and precision can not meet the accuracy requirement increasingly increasing；(3) there is no blood sugar test
Controlling mechanism with insulin supply, it is impossible to the blood-sugar content self-adaptative adjustment according to tested human body is tested
The supply parameter of the insulin of personnel, for example, feed speed, quantity delivered etc., in addition it is also necessary to manual observation
Blood-sugar content, manual decision's insulin supply parameter, automatization level falls behind；(4) radio communication
Interface is deficient, it is impossible to the parameters related to blood sugar is timely fed back to medical server end, even if
There is some simple wireless communication interfaces, such as bluetooth communication interface, its matching mechanisms and connection machine
Inefficiency processed, can not meet the requirement of the high speed transmission data of medical device.
To this end, the present invention proposes a kind of enhancing computer aided medicine system, can improve backward
Pulse detection is dissolved in blood glucose meter by the structure of blood glucose meter, widens the scope of the physiological parameter of detection,
Improve the precision of blood sugar test, the insulin delivery system that blood sugar automatically controls can be set up, reduce people
Work participates in, in addition it is possible to improve existing Bluetooth communication mechanism, improves the speed of Wireless Data Transmission
Degree and efficiency, thus, improve the intelligent level of blood glucose meter on the whole.
Fig. 1 is the structure square frame of the first embodiment of the enhancing computer aided medicine system of the present invention
Figure, described accessory system includes Automatic insulin injection subsystem, pulse detection subsystem, blood sugar inspection
Surveying subsystem and AVR32 chip, described pulse detection subsystem and described blood sugar test subsystem are respectively
For extracting pulse data and the blood glucose level data of tested personnel, described AVR32 chip and described insulin
Automatic injection subsystems, described pulse detection subsystem and described blood sugar test subsystem connect respectively,
Determine whether to send cacosphyxia identification signal, base based on the pulse data of described pulse detection subsystem
Determine whether to control described Automatic insulin injection in the blood glucose level data of described blood sugar test subsystem
System is the automatic insulin injection of tested personnel.
Then, the concrete of the second embodiment strengthening computer aided medicine system to the present invention is continued
Structure is further detailed.
Described accessory system includes: enzyme electrode sensor, including reference electrode, to pole electrode and work
Three electrodes of electrode, working electrode are fixed with glucose oxidase, wherein, when the quilt of tested personnel
Survey blood sample when being dropped in the test zone of working electrode, glucose oxidase fixing on working electrode with
In glucose generation chemical reaction in tested blood sample, the response current on working electrode and tested blood sample
Concentration of glucose linear.
Described accessory system includes: amplifying circuit, is connected with described enzyme electrode sensor, is used for receiving
And amplify response current on working electrode；Low pass filter, is connected with described amplifying circuit, is used for
Receive and filter the radio-frequency component in response current；MMC storage card, is used for storing preset ratio system
Number；First resistance, one end is connected with 5V power supply, and the other end connects with the anode of infrared receiving diode
Connect；Second resistance, one end is connected with 5V power supply, and one end of the other end and the 3rd resistance connects；The
Three resistance, the other end is grounded, and has the resistance identical with the second resistance；First two-way operation amplifier
Device, for producing the reference voltage of 2.5V, the other end of its anode and the second resistance connects, negative terminal and
One end of first electric capacity connects, and output is connected with the negative terminal of infrared-emitting diode, negative terminal also with red
The negative terminal of emission diode connects.
Described accessory system includes: the first electric capacity, and the other end is grounded；4th resistance, one end with infrared
The negative terminal of emitting diode connects；Second two-way operational amplifier, the other end of anode and the 4th resistance
Connecting, negative terminal is connected with the anode of infrared receiving diode, and output is as pulse voltage；5th electricity
Resistance, is connected in parallel between the second two-way operational amplifier negative terminal and the second two-way operational amplifier output terminal；
Second electric capacity, is connected in parallel on the second two-way operational amplifier negative terminal and the second two-way operational amplifier output terminal
Between；Infrared-emitting diode, is arranged on tested personnel ear capillary position, is used for launching red
Outer light, the negative terminal of infrared-emitting diode is connected with the anode of infrared receiving diode；Infrared receiver two
Pole is managed, and is arranged on tested personnel ear capillary position, is positioned at the phase of described infrared-emitting diode
To position, for receiving the infrared light after transmission tested personnel ear capillary.
Described accessory system includes: AVR32 chip, deposits with described low pass filter and described MMC
Card storage connects respectively, calculates the blood of tested personnel based on preset ratio coefficient and filtered response current
Sugar concentration, wherein, preset ratio coefficient is in the response current on decision working electrode and tested blood sample
Concentration of glucose between the ratio of linear relationship；Described AVR32 chip is also transported with described second two-way
The output calculating amplifier connects to obtain described pulse voltage, and when described pulse voltage is at default arteries and veins
When outside scope of fighting, send cacosphyxia identification signal, when described blood sugar concentration is in the default blood sugar upper limit
During concentration, send blood sugar concentration too high identification signal, when described blood sugar concentration is dense at default blood sugar lower limit
When spending, send blood sugar concentration too low identification signal.
Described accessory system includes: insulin storage device, for prestoring the pancreas islet of preset capacity
Element；Liquid level detection device, is positioned at described insulin storage device, deposits for real-time detection insulin
Insulin liquid level in storage equipment, and when insulin liquid level is equal to or less than preset reference liquid level, send out
Going out insufficient insulin alarm signal, described liquid level detection device is also connected with described AVR32 chip to incite somebody to action
Described insufficient insulin alarm signal is sent to described AVR32 chip.
Described accessory system includes: insulin drives equipment, is connected with described AVR32 chip, when
When receiving described blood sugar concentration too high identification signal, dense according to the blood sugar that described AVR32 chip forwards
The difference of degree and described default blood sugar upper concentration determines insulin pump drive signal, described insulin pump
Drive value and the speed of the supply insulin of signal deciding insulin pump；Insulin pump, and described
Insulin storage device and insulin infusion device connect respectively, drive equipment even with described insulin
Connect, under the control of described insulin driving equipment, by the pancreas in described insulin storage device
Island element is expelled in tested personnel's body by insulin infusion device；Insulin infusion device, detachably
Formula is embedded in tested personnel's body, for tested personnel's insulin injection.
Described accessory system includes: serial communication circuit, is positioned at AVR32 chip and leads to Bluetooth matching
Between letter equipment, for described blood sugar concentration and described insufficient insulin alarm signal are sent to bluetooth
Matched communicating devices.
Described accessory system includes: Bluetooth matching communication equipment, for by described blood sugar concentration and described
Insufficient insulin alarm signal is wirelessly transmitted to the target Bluetooth devices connecting；Described Bluetooth matching leads to
Letter equipment includes the first search subset, the second search subset and coupling connexon equipment；First searches
Large rope equipment, determines Bluetooth MAC address concentration according to MAC Address concentration in Bluetooth Scatternet
High micro bluetooth network is as target piconet, and a Bluetooth Scatternet is by multiple micro bluetooth network groups
Become；Second search subset, is connected with described first search subset, in described target piconet,
Find, quantity preceding by signal strength signal intensity ranking to be not more than one or more Bluetooth matching communications of 7 and set
Standby as one or more target Bluetooth devices；Equipment connexon equipment, sets with described second search
Standby connection, starts and is connected with the Bluetooth communication of the one or more target Bluetooth devices.
Wherein, when the Bluetooth matching communication equipment having signal in described target piconet quantity for more than
During equal to 7, the quantity of the one or more target Bluetooth devices is 7, when described target is slight
When net having the quantity of the Bluetooth matching communication equipment of signal be less than 7, the one or more target
The quantity of bluetooth equipment is the quantity of the Bluetooth matching communication equipment having signal in described target piconet.
Wherein, described MMC storage card is connected with described AVR32 chip, and prestores described default arteries and veins
Fight scope, described default blood sugar upper concentration and described default blood sugar least concentration.
Alternatively, in described enhancing computer aided medicine system: when infrared-emitting diode and red
Between outer reception diode during pulseless, pulse voltage is 2.5V, when infrared-emitting diode and infrared
When there is, between reception diode, the pulse beated, blood vessels make ear's light transmission be deteriorated, and pulse voltage is big
In 2.5V；First two-way operational amplifier and the second two-way operational amplifier are all the two-way of TI company
Operational amplifier；Described serial communication circuit is RS232 serial communication interface；Described AVR32 core
Piece when sending cacosphyxia identification signal, blood sugar too high identification signal or hypoglycemia identification signal,
Being simultaneously emitted by abnormality signal, otherwise, described AVR32 chip is simultaneously emitted by normal state signal.
In addition, wave filter, as the term suggests, it is the device that ripple is filtered." ripple " be one non-
Often extensive physical concept, at electronic technology field, " ripple " is narrowly confined to refer in particular to describe respectively
Plant the process of the value fluctuations in time of physical quantity.The effect by various kinds of sensors for this process,
It is converted into the function of time of voltage or electric current, the time waveform of referred to as various physical quantitys, or claim
Be signal.Because the independent variable time is continuous value, so referred to as continuous time signal, again
It is referred to as analog signal habitually.
With the generation of digital electronic computer technology with develop rapidly, for the ease of computer to letter
Number process, create and continuous time signal is transformed into discrete time letter under sampling theorem instructs
Number complete theory and method.It is to say, can only use original analog signal when series of discrete
Between sample value in coordinate points express primary signal and do not lose any information, ripple, waveform, signal this
It since what a little concepts were expressed is the change of various physical quantitys in objective world, is exactly that modern society relies naturally
Carrier with the various information of existence.Information needs to propagate, and lean on is exactly the transmission of waveform signal.Letter
Number it generation, conversion, transmission each link may be due to the existence of environment and interference
Distortion, even in quite a number of cases, this distortion is also very serious, causes signal and is taken
The information of band is embedded in the middle of noise dearly.In order to filter these noises, recover the signal of script,
Need to use various wave filter to be filtered processing.
Use the enhancing computer aided medicine system of the present invention, tie for blood sugar instrument in prior art
Structure backwardness and the technical problem of radio communication function difference, optimize the structure of existing blood sugar instrument, add
Pulse detection equipment and blood sugar concentration automatic control equipment, also improve existing bluetooth communication interface simultaneously
Communication performance, thus improve the level of its medical services.
Although it is understood that the present invention discloses as above with preferred embodiment, but above-mentioned enforcement
Example is not limited to the present invention.For any those of ordinary skill in the art, without departing from
Under technical solution of the present invention ambit, all may utilize the technology contents of the disclosure above to the technology of the present invention
Scheme makes many possible variations and modification, or is revised as the Equivalent embodiments of equivalent variations.Therefore,
Every content without departing from technical solution of the present invention, the technical spirit of the foundation present invention is to above example
Any simple modification, equivalent variations and the modification done, all still falls within technical solution of the present invention protection
In the range of.
Claims (1)
1. strengthening a computer aided medicine system, described accessory system includes that insulin is noted automatically
Penetrating subsystem, pulse detection subsystem, blood sugar test subsystem and AVR32 chip, described pulse is examined
Survey subsystem and described blood sugar test subsystem is respectively used to extract pulse data and the blood of tested personnel
Sugar data, described AVR32 chip and described Automatic insulin injection subsystem, described pulse detection
System and described blood sugar test subsystem connect respectively, based on the Pulse Rate of described pulse detection subsystem
According to determining whether to send cacosphyxia identification signal, based on the blood glucose level data of described blood sugar test subsystem
Determine whether that controlling described Automatic insulin injection subsystem is the automatic insulin injection of tested personnel；
It is characterized in that, described accessory system includes:
Enzyme electrode sensor, including reference electrode, to pole electrode and three electrodes of working electrode, work
It is fixed with glucose oxidase, wherein, when the tested blood sample of tested personnel is dropped in work electricity on electrode
During the test zone of pole, glucose oxidase fixing on working electrode and the glucose in tested blood sample
Chemical reaction occurs, and the response current on working electrode is with the concentration of glucose in tested blood sample linearly
Relation；
Amplifying circuit, is connected with described enzyme electrode sensor, for receiving and amplifying on working electrode
Response current；
Low pass filter, is connected with described amplifying circuit, for receiving and filtering the height in response current
Frequently composition；
MMC storage card, is used for storing preset ratio coefficient；
First resistance, one end is connected with 5V power supply, and the other end connects with the anode of infrared receiving diode
Connect；
Second resistance, one end is connected with 5V power supply, and one end of the other end and the 3rd resistance connects；
3rd resistance, the other end is grounded, and has the resistance identical with the second resistance；
First two-way operational amplifier, for producing reference voltage, its anode and second resistance of 2.5V
The other end connect, one end of negative terminal and the first electric capacity connects, output and infrared-emitting diode
Negative terminal connects, and negative terminal is also connected with the negative terminal of infrared-emitting diode；
First electric capacity, the other end is grounded；
4th resistance, one end is connected with the negative terminal of infrared-emitting diode；
Second two-way operational amplifier, the other end of anode and the 4th resistance connects, and negative terminal connects with infrared
The anode receiving diode connects, and output is as pulse voltage；
5th resistance, is connected in parallel on the second two-way operational amplifier negative terminal and the second two-way operational amplifier is defeated
Go out between end；
Second electric capacity, is connected in parallel on the second two-way operational amplifier negative terminal and the second two-way operational amplifier is defeated
Go out between end；
Infrared-emitting diode, is arranged on tested personnel ear capillary position, is used for launching infrared
Light, the negative terminal of infrared-emitting diode is connected with the anode of infrared receiving diode；
Infrared receiving diode, is arranged on tested personnel ear capillary position, is positioned at described infrared
The relative position of emitting diode, infrared for receive after transmission tested personnel ear capillary
Light；
AVR32 chip, is connected respectively with described low pass filter and described MMC storage card, based on
Preset ratio coefficient and filtered response current calculate the blood sugar concentration of tested personnel, wherein, preset
Proportionality coefficient is for determining between the response current on working electrode and the concentration of glucose in tested blood sample
The ratio of linear relationship；The output also with described second two-way operational amplifier for the described AVR32 chip
Connect to obtain described pulse voltage, and when described pulse voltage is outside default pulse range, send out
Go out cacosphyxia identification signal, when described blood sugar concentration is at default blood sugar upper concentration, send blood sugar
Excessive concentration identification signal, when described blood sugar concentration is at default blood sugar least concentration, sends blood sugar dense
Spend low identification signal；
Insulin storage device, for prestoring the insulin of preset capacity；
Liquid level detection device, is positioned at described insulin storage device, deposits for real-time detection insulin
Insulin liquid level in storage equipment, and when insulin liquid level is equal to or less than preset reference liquid level, send out
Going out insufficient insulin alarm signal, described liquid level detection device is also connected with described AVR32 chip to incite somebody to action
Described insufficient insulin alarm signal is sent to described AVR32 chip；
Insulin drives equipment, is connected with described AVR32 chip, when receiving described blood sugar concentration mistake
During high identification signal, the blood sugar concentration forwarding according to described AVR32 chip and the described default blood sugar upper limit
The difference of concentration determines insulin pump drive signal, and described insulin pump drives signal deciding insulin
The value of the supply insulin of pump and speed；
Insulin pump, connects respectively with described insulin storage device and insulin infusion device, with institute
Stating insulin drives equipment to connect, under the control of described insulin driving equipment, by described pancreas
Insulin in the element storage device of island is expelled in tested personnel's body by insulin infusion device；
Insulin infusion device, detachable is embedded in tested personnel's body, for tested personnel's note
Penetrate insulin；
Serial communication circuit, is positioned between AVR32 chip and Bluetooth matching communication equipment, for by institute
State blood sugar concentration and described insufficient insulin alarm signal is sent to Bluetooth matching communication equipment；
Bluetooth matching communication equipment, for by described blood sugar concentration and described insufficient insulin alarm signal
It is wirelessly transmitted to the target Bluetooth devices on connecting；Described Bluetooth matching communication equipment includes the first search
Subset, the second search subset and coupling connexon equipment；Wherein, the first search subset, root
Determine that the bluetooth that Bluetooth MAC address concentration is the highest is slight according to MAC Address concentration in Bluetooth Scatternet
Net is as target piconet, and a Bluetooth Scatternet is made up of multiple micro bluetooth networks；Second search
Equipment, is connected with described first search subset, and in described target piconet, it is strong that signal is pressed in searching
Ranking is preceding for degree, quantity be not more than one or more Bluetooth matching communication equipments of 7 as one or
Multiple target Bluetooth devices；Equipment connexon equipment, is connected with described second search subset, starts
It is connected with the Bluetooth communication of the one or more target Bluetooth devices；
Wherein, when the Bluetooth matching communication equipment having signal in described target piconet quantity for more than
During equal to 7, the quantity of the one or more target Bluetooth devices is 7, when described target is slight
When net having the quantity of the Bluetooth matching communication equipment of signal be less than 7, the one or more target
The quantity of bluetooth equipment is the quantity of the Bluetooth matching communication equipment having signal in described target piconet；
Wherein, described MMC storage card is connected with described AVR32 chip, and prestores described pre-
If pulse range, described default blood sugar upper concentration and described default blood sugar least concentration；
Between infrared-emitting diode and infrared receiving diode during pulseless, pulse voltage is
2.5V, when there is, between infrared-emitting diode and infrared receiving diode, the pulse beated, blood vessels
Making ear's light transmission be deteriorated, pulse voltage is more than 2.5V；
First two-way operational amplifier and the second two-way operational amplifier are all the two-way computing of TI company
Amplifier.
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