CN105456926A - Traditional Chinese medicine preparation for treating epilepsy - Google Patents
Traditional Chinese medicine preparation for treating epilepsy Download PDFInfo
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- CN105456926A CN105456926A CN201510944322.6A CN201510944322A CN105456926A CN 105456926 A CN105456926 A CN 105456926A CN 201510944322 A CN201510944322 A CN 201510944322A CN 105456926 A CN105456926 A CN 105456926A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
- A61K35/10—Peat; Amber; Turf; Humus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Abstract
A traditional Chinese medicine preparation for treating epilepsy is prepared from, by weight, 3 g of geckos (dried gecko bodies), 10 g of manyleaf paris rhizomes, 10 g of white muscardin silkworms, 15 g of chlorite schists, 15 g of rhizoma acori graminei and 10 g of liquorice. The traditional Chinese medicine preparation has the functions of dissipating phlegm for resuscitation, relieving spasm and epilepsy and restoring consciousness and soothing the nerves and is mainly used for treating panic, mania, grand mal and petit mal and the like. Due to the fact that natural medicines are used in the traditional Chinese medicine preparation, the advantages of being capable of quickly achieving the effects, good in treating effect and free of toxic and side effects are achieved.
Description
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine preparation being used for the treatment of epileptics.
Background technology
Epilepsy (EpicenePSY) is commonly called as " epilepsy " " epilepsy ", and south is named " sow is crazy ".Because primary disease is complicated, add and make a return journey rapidly, as ordinary person after waking up, for diagnosis and treatment bring extreme difficulties, there is no specific short both at home and abroad at present.Primary disease suffers from congenital factors, but the day after tomorrow, gained was common.Acquired disposition is a kind of situation of brain function exception, with the convulsion of paroxysm (convulsive attack) and for the moment loss of consciousness for main feature.
The view of the traditional Chinese medical science just has the record about epileptics.Mainly fatigue is impairment of the kidney the raw expectorant of QI rising in reverse order, expectorant heat-dissipating, hot air wind producing, and so-called " gas " both can make a general reference the normal physiological function of human body, as the gas in QI and blood, also specifically can represent the normal physiological of a certain internal organs, as irritability, also can represent Nervous and Mental Factors, as on gas disease etc.After the normal operation of these " gas " is hindered, just can cause a kind of morbid state, be namely " expectorant ", this " expectorant " does not refer to cough expectorant out.The morbid state persistent period is of a specified duration, and this morbid state worsens further again, will produce the symptom of convulsion.
Due to expectorant serious time also can directly cause stupor, the former is agnogenio, because not found the change on pathomorphism in brain, therefore is also called functional epilepsy.The latter's cause of disease is clear and definite, caused by the sequela of various encephalopathy, as encephalitis, cerebral trauma, maternal infuries, cerebral cysticercosis, cerebrovascular, poisoning and neurodegenerative disease etc.
The type of epilepsy is a lot, have to divide by the cause of disease, have to divide by inducement, have to divide by the region of anatomy, has to divide by a symptom, has to divide by mode of onset i.e. one group of symptom.Each have their own basis is for the ease of Treatment and diagnosis typing.But at the typing that China relatively passes through, or add the comprehensive classification of the form of work with the cause of disease.Such as essential epilepsy grand mal type, secondary epilepsy topical type etc.The traditional Chinese medical science, in epilepsy classification, be always classify by the cause of disease of gas, blood, phlegm-fire and yin, yang, void, on the spot symptom, but emphasis is the excess syndrome caused by phlegm-fire.
Also there are some method for the treatment of this type of disease, medicines in the market, all have such or such deficiency, the effect for the treatment of both the principal and secondary aspects of a disease can not be reached.
Summary of the invention
It is simple that technical problem to be solved by this invention is to provide a kind of combination, the eutherapeutic Chinese medicine preparation being used for the treatment of epileptics.
Technical problem to be solved by this invention realizes by the following technical solutions:
Be used for the treatment of a Chinese medicine preparation for epileptics, be made up of the component of following weight: Gekko Swinhonis (Gekko Swinhonis) 3g, Rhizoma Paridis 10g, Bombyx Batryticatus 10g, Lapis Micae Aureus 15g, Rhizoma Acori Graminei 15g, Radix Glycyrrhizae 10g.
Patient for recurrent exerbation also adds: Concretio Silicea Bambusae 5g, Ramulus Uncariae Cum Uncis 15g, Dens Draconis 20g, Fructus Gardeniae 10g, Haematitum 10g, succinum 10g, Scorpio 10g, Radix Polygalae 20g, Radix Sorghum vulgare Pers. 10g, Rhizoma Curcumae 10g.
Usage 1: be decocted in water for oral dose, Lapis Micae Aureus is decocted first, sooner or later each potion, 1 course for the treatment of Monday, and general 8 courses for the treatment of cure.
Usage 2: powder process agent, warm water is taken after mixing it with water, sooner or later each potion, 1 course for the treatment of Monday, and general 8 courses for the treatment of cure.
Usage 3: pill agent, as Semen phaseoli radiati size, each potion sooner or later, 1 course for the treatment of Monday, general 8 courses for the treatment of cure.
Function cures mainly: have one's ideas straightened out eliminate the phlegm, spasmolytic determines epilepsy, refreshment and tranquilization.For frightened, mad, large petit mal of epilepsy etc.
Fang Xie:
Gekko Swinhonis (Gekko Swinhonis): expelling wind for relieving convulsion, relieving convulsion, poison eliminates the phlegm, determine epilepsy, is monarch drug;
Rhizoma Paridis: heat-clearing and toxic substances removing, dispelling wind and relieving convulsion, relieving convulsion determine epilepsy is accessory drugs;
Bombyx Batryticatus: spasmolytic endogenous wind stopping, dispel the wind and determine epilepsy, reduce phlegm that it is frightened to dispel is accessory drugs;
Lapis Micae Aureus: checking hyperfunction of the liver for relieving convulsion, expectorant determine epilepsy is adjuvant drug;
Rhizoma Acori Graminei: inducing resuscitation, spasmolytic determine epilepsy, position adjuvant drug;
Radix Glycyrrhizae: coordinating the actions of various ingredients in a prescription, spleen invigorating and in, for making medicine;
Monarch, minister, help, make, all medicines share, and play the merit that spasmolytic determines epilepsy, consciousness-restoring and orifice-opening altogether.
Indication and taboo:
Indication: for the treatment of various epileptics.Comprise grand mal, petit mal, psychomotor attack, autonomic seizures, various types of epilepsy symptoms kind more than 70 such as constitutional, Secondary cases, seriality outbreak.
Taboo: period in a medicine avoids tobacco and wine, Fructus Capsici, rareripe, raw Bulbus Allii, Rhizoma Zingiberis Recens, mustard, mutton cubes roasted on a skewer, avoids high light to stimulate.
The present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.Its test method and result of the test are distinguished as follows:
1) animal acute toxicity test is carried out to decoction prepared by the present invention:
Medicine: the crude drug used by the present invention is bought from common Chinese shop and obtained, and its specification meets national Chinese crude drug standard.
Experimental animal: white mice, body weight is at about 50g, and male and female Stochastic choice, is bought by market.
Method and result: get white mice 10, hungry 20 hours, fill with for 5 times by every only every natural gift and feed 50ml, feed one week continuously, observe 10 days, mice is movable normal, non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.
2) long-term toxicity test for animals is carried out to decoction prepared by the present invention:
Experimental animal: rat, body weight is at 120-130g, and male and female Stochastic choice, is bought by market.
Method and result: get rat 20, be divided into 2 groups, often organize 10, wherein the 1st group as administration group, feed by filling with for 2 times every every day, each 5-10ml is not etc., 2nd group of diet as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, equal non-toxic reaction, a kind of safe drugs.
The invention has the beneficial effects as follows: the present invention adopts Chinese herbal medicine formula, material is easy to get, and preparation method is simple, and therapeutic effect is good, and price is low, instant effect, and curative effect is reliable, with system with without obvious adverse reaction and side effect.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
Be used for the treatment of a Chinese medicine preparation for epileptics, be made up of the component of following weight: Gekko Swinhonis (Gekko Swinhonis) 3g, Rhizoma Paridis 10g, Bombyx Batryticatus 10g, Lapis Micae Aureus 15g, Rhizoma Acori Graminei 15g, Radix Glycyrrhizae 10g.
Usage: be decocted in water for oral dose, Lapis Micae Aureus is decocted first, sooner or later each potion, 1 course for the treatment of Monday, and general 8 courses for the treatment of cure.
Function cures mainly: have one's ideas straightened out eliminate the phlegm, spasmolytic determines epilepsy, refreshment and tranquilization.For frightened, mad, large petit mal of epilepsy etc.
Embodiment 2
Be used for the treatment of a Chinese medicine preparation for epileptics, be made up of the component of following weight: Gekko Swinhonis (Gekko Swinhonis) 3g, Rhizoma Paridis 10g, Bombyx Batryticatus 10g, Lapis Micae Aureus 15g, Rhizoma Acori Graminei 15g, Radix Glycyrrhizae 10g, Concretio Silicea Bambusae 5g, Ramulus Uncariae Cum Uncis 15g, Dens Draconis 20g, Fructus Gardeniae 10g, Haematitum 10g, succinum 10g, Scorpio 10g, Radix Polygalae 20g, Radix Sorghum vulgare Pers. 10g, Rhizoma Curcumae 10g.
Usage: powder process agent, warm water is taken after mixing it with water, sooner or later each potion, 1 course for the treatment of Monday, and general 8 courses for the treatment of cure.
Function cures mainly: have one's ideas straightened out eliminate the phlegm, spasmolytic determines epilepsy, refreshment and tranquilization.For frightened, mad, large petit mal of epilepsy etc.
Embodiment 3
Be used for the treatment of a Chinese medicine preparation for epileptics, be made up of the component of following weight: Gekko Swinhonis (Gekko Swinhonis) 3g, Rhizoma Paridis 10g, Bombyx Batryticatus 10g, Lapis Micae Aureus 15g, Rhizoma Acori Graminei 15g, Radix Glycyrrhizae 10g, Concretio Silicea Bambusae 5g, Ramulus Uncariae Cum Uncis 15g, Dens Draconis 20g, Fructus Gardeniae 10g, Haematitum 10g, succinum 10g, Scorpio 10g, Radix Polygalae 20g, Radix Sorghum vulgare Pers. 10g, Rhizoma Curcumae 10g.
Usage: be decocted in water for oral dose, Lapis Micae Aureus is decocted first, sooner or later each potion, 1 course for the treatment of Monday, and general 8 courses for the treatment of cure.
Function cures mainly: have one's ideas straightened out eliminate the phlegm, spasmolytic determines epilepsy, refreshment and tranquilization.For frightened, mad, large petit mal of epilepsy etc.
Clinical experiment therapeutic effect:
1, epileptics diagnostic criteria
Tcm diagnosis meets following symptom for epileptics: petit mal: stop suddenly, stop, and nods, blinks and can swoon with headache stomachache acroesthesia eye is confused; Grand mal: to spit out white foams, tic of the limbs, gatism, gnathospasma.
2, administrated method
By above-mentioned usage and dosage, according to the rational use of drug of state of an illness weight.
3, curative effect statistics
Through clinical treatment decades, statistics case 2500 example, wherein female 1125 example, man 1375 example; 1-3 year 415 example, 4-14 year 1340 example, 15 years old to adult 745 example; What the course of disease was the shortest is 4 weeks, and what the course of disease was the longest is 20 years.Effective percentage is 90%, cure rate 80%, inefficiency 10%.Cause invalid reason many because adult's course of disease is long, take Western medicine addiction for a long time again, have dependency, Bu Nengting, add thought pressure, family burden, economic cause etc., take medicine of the present invention and just stopped less than two months, therefore be difficult to ensure curative effect.
4, curative effect judging standard
Cure and do not recur for latter 3 years, for curing; Symptom obviously alleviates, and electroencephalogram spike is clearly better, and attack times reduces, and the persistent period shortens, for effectively.
Model case:
1, still so-and-so, man, 18 years old, people from Jieshou City, Anhui Province.The course of disease is had a surplus for 2 years, essential epilepsy, duration of seizure 8-10 minute, once accepts acupuncture, cmm of simple prescription and Western medicine Antiepileptic Drugs, and effect is unsatisfied with.Take 4 courses for the treatment of of the embodiment of the present invention 1 medicine, various symptom obviously alleviates, and intermission electroencephalogram is normal.
2, poplar, female, 29 years old, people from Jieshou City, Anhui Province.The course of disease is had a surplus for 4 years, and secondary epilepsy takes Western medicine sodium valproate, phenobarbital, phenytoin Sodium, DeGrain.After take the embodiment of the present invention 2 Chinese medicine, every day 2 times, continuous one month, attack times first subtracted and stops afterwards, continued to take after 1 month and did not all reaccess, also there are no toxic and side effects, follow up a case by regular visits to and do not recur so far.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (1)
1. be used for the treatment of a Chinese medicine preparation for epileptics, it is characterized in that, be made up of the component of following weight: Gekko Swinhonis 3g, Rhizoma Paridis 10g, Bombyx Batryticatus 10g, Lapis Micae Aureus 15g, Rhizoma Acori Graminei 15g, Radix Glycyrrhizae 10g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510944322.6A CN105456926A (en) | 2015-12-15 | 2015-12-15 | Traditional Chinese medicine preparation for treating epilepsy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510944322.6A CN105456926A (en) | 2015-12-15 | 2015-12-15 | Traditional Chinese medicine preparation for treating epilepsy |
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| Publication Number | Publication Date |
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| CN105456926A true CN105456926A (en) | 2016-04-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510944322.6A Pending CN105456926A (en) | 2015-12-15 | 2015-12-15 | Traditional Chinese medicine preparation for treating epilepsy |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109731067A (en) * | 2019-03-21 | 2019-05-10 | 别晨光 | A kind of preparation method of the Chinese medicine composition for treating various epileptics and Chinese medicine |
-
2015
- 2015-12-15 CN CN201510944322.6A patent/CN105456926A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 徐三文等: "《中国脑病秘方全书》", 31 August 2002, 科学技术文献出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109731067A (en) * | 2019-03-21 | 2019-05-10 | 别晨光 | A kind of preparation method of the Chinese medicine composition for treating various epileptics and Chinese medicine |
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Application publication date: 20160406 |
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