CN102657836B - Medicine composition used for treating insomnia - Google Patents
Medicine composition used for treating insomnia Download PDFInfo
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- CN102657836B CN102657836B CN 201210168022 CN201210168022A CN102657836B CN 102657836 B CN102657836 B CN 102657836B CN 201210168022 CN201210168022 CN 201210168022 CN 201210168022 A CN201210168022 A CN 201210168022A CN 102657836 B CN102657836 B CN 102657836B
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Abstract
The invention discloses a medicine composition used for treating insomnia, comprising medicated leaven, radix cyathulae, root of straight ladybell, radix paeoniae alba, radix rehmanniae preparata, incised notopterygium, anise, spina date seed, radix peucedani, cinnamon, barbary wolfberry fruit, radix clematidis, liquorice, Indian bread with pine, mangosteen, common selfheal fruit-spike, common floweringquince fruit, cortex eucomiae, rhizoma chuanxiong, radix gentianae macrophyllae, divaricate saposhnikovia root, root of doubleteeth pubescent angelica, jujube and ginger. The medicine composition disclosed by the invention can be prepared in the clinically acceptable forms of medicinal liquor, tablets, capsules, granules, pills, powder, decoction or oral liquid by adding conventional auxiliary material according to a conventional process. The medicine composition disclosed by the invention has the functions of heath care and life nourishing, enhancing organic tissue function adjustment and heath maintenance. The medicine composition has obvious effect for insomnia and no side effects.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition of Cure for insomnia.
Background technology
Insomnia refers to fall asleep and maybe can't keep sleep state, causes not having enough sleep.Claiming DIMS (DlMS) again, for a variety of causes causes that difficulty falling asleep, Depth of sleep or frequency are too short, early awakening and the length of one's sleep are not enough or of poor quality etc., is a kind of commonly encountered diseases.Insomnia is owing to feelings will, diet internal injury, or reaches the causes of disease such as old, innate deficiency, timidness due to deficiency of the heart after being ill, causes lack of preservation of spirit or irritability, thereby causes often can not obtaining the class disease that ortho sleep is feature.Insomnia mainly show as the not enough of the length of one's sleep, the degree of depth and can not allaying tiredness, regain one's strength and energy, the lighter's difficulty falling asleep, or sleep but not soundly, sometimes sleeping and sometimes waking, or can not sleep again after waking up, heavy then be insomnia all night.Insomnia is one of common clinical disease, though do not belong to critical illness, hinders people orthobiosis, work, study and health, and can increase the weight of or bring out diseases such as cardiopalmus, the thoracic obstruction, dizzy, headache, apoplexy.Obstinate insomnia brings long-term misery to patient, even forms the dependence to the medicine of sleeping peacefully, and can cause iatrogenic disease and take the medicine of sleeping peacefully for a long time.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition of Cure for insomnia.
The present invention is achieved through the following technical solutions:
The crude drug of pharmaceutical composition of the present invention consists of:
Massa Medicata Fermentata 2-8 weight portion Radix Cyathulae 5-15 weight portion Radix Adenophorae (Radix Glehniae) 10-30 weight portion
Radix Paeoniae Alba 7-23 weight portion Radix Rehmanniae Preparata 5-15 weight portion Rhizoma Et Radix Notopterygii 2-8 weight portion
Fructus Anisi Stellati 5-15 weight portion Semen Ziziphi Spinosae 15-45 weight portion Radix Peucedani 5-15 weight portion
Cortex Cinnamomi 5-15 weight portion Fructus Lycii 5-15 weight portion Radix Clematidis 5-15 weight portion
Radix Glycyrrhizae 5-15 weight portion Poria cum Radix Pini 5-15 weight portion Garcinia mangostana 5-15 weight portion
Spica Prunellae 5-15 weight portion Fructus Chaenomelis 7-23 weight portion Cortex Eucommiae 5-15 weight portion
Rhizoma Chuanxiong 7-23 weight portion Radix Gentianae Macrophyllae 5-15 weight portion Radix Saposhnikoviae 7-23 weight portion
Radix Angelicae Pubescentis 2-8 weight portion Fructus Jujubae 5-15 weight portion Rhizoma Zingiberis Recens 5-15 weight portion.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Massa Medicata Fermentata 5 weight portion Radix Cyathulaes 10 weight portion Radix Adenophorae (Radix Glehniae) 20 weight portions
The Radix Paeoniae Alba 15 weight portion Radix Rehmanniaes Preparata 10 weight portion Rhizoma Et Radix Notopterygiis 5 weight portions
Fructus Anisi Stellati 10 weight portion Semen Ziziphi Spinosaes 30 weight portion Radix Peucedanis 10 weight portions
Cortex Cinnamomi 10 weight portion Fructus Lyciis 10 weight portion Radix Clematidis 10 weight portions
Radix Glycyrrhizae 10 weight portion Poria cum Radix Pinis 10 weight portion Garcinia mangostana 10 weight portions
The Spica Prunellae 10 weight portion Fructus Chaenomeliss 15 weight portion Cortexs Eucommiae 10 weight portions
Rhizoma Chuanxiong 15 weight portion Radix Gentianae Macrophyllae 10 weight portion Radix Saposhnikoviaes 15 weight portions
Radix Angelicae Pubescentis 5 weight portion Fructus Jujubaes 10 weight portion Rhizoma Zingiberis Recenss 10 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Massa Medicata Fermentata 4 weight portion Radix Cyathulaes 13 weight portion Radix Adenophorae (Radix Glehniae) 12 weight portions
The Radix Paeoniae Alba 21 weight portion Radix Rehmanniaes Preparata 7 weight portion Rhizoma Et Radix Notopterygiis 6 weight portions
Fructus Anisi Stellati 7 weight portion Semen Ziziphi Spinosaes 43 weight portion Radix Peucedanis 7 weight portions
Cortex Cinnamomi 13 weight portion Fructus Lyciis 7 weight portion Radix Clematidis 13 weight portions
Radix Glycyrrhizae 7 weight portion Poria cum Radix Pinis 13 weight portion Garcinia mangostana 7 weight portions
The Spica Prunellae 13 weight portion Fructus Chaenomeliss 9 weight portion Cortexs Eucommiae 13 weight portions
Rhizoma Chuanxiong 9 weight portion Radix Gentianae Macrophyllae 13 weight portion Radix Saposhnikoviaes 9 weight portions
Radix Angelicae Pubescentis 6 weight portion Fructus Jujubaes 7 weight portion Rhizoma Zingiberis Recenss 13 weight portions.
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Massa Medicata Fermentata 6 weight portion Radix Cyathulaes 7 weight portion Radix Adenophorae (Radix Glehniae) 28 weight portions
The Radix Paeoniae Alba 9 weight portion Radix Rehmanniaes Preparata 13 weight portion Rhizoma Et Radix Notopterygiis 4 weight portions
Fructus Anisi Stellati 13 weight portion Semen Ziziphi Spinosaes 17 weight portion Radix Peucedanis 13 weight portions
Cortex Cinnamomi 7 weight portion Fructus Lyciis 13 weight portion Radix Clematidis 7 weight portions
Radix Glycyrrhizae 13 weight portion Poria cum Radix Pinis 7 weight portion Garcinia mangostana 13 weight portions
The Spica Prunellae 7 weight portion Fructus Chaenomeliss 21 weight portion Cortexs Eucommiae 7 weight portions
Rhizoma Chuanxiong 21 weight portion Radix Gentianae Macrophyllae 7 weight portion Radix Saposhnikoviaes 21 weight portions
Radix Angelicae Pubescentis 4 weight portion Fructus Jujubaes 13 weight portion Rhizoma Zingiberis Recenss 7 weight portions.
Pharmaceutical composition of the present invention adds conventional adjuvant according to common process and makes the medicated wine of clinical acceptance, tablet, capsule, granule, pill, powder, decoction or oral liquid.
Pharmaceutical composition of the present invention has the health care, and enhancing body function of organization regulates and maintenance.Remarkable to controlling the insomnia effect, have no side effect.
Following experimental example is used for further specifying the present invention, but is not limited to the present invention.
One, experimental example clinical trial
1, clinical observation
Medicated wine of the present invention (according to embodiment 1 method preparation), Cure for insomnia 60 examples, male's 30 examples wherein, women's 30 examples, age 30-70 year.
2, Therapeutic Method
Medicated wine of the present invention (according to the preparation of embodiment 1 method), every day 2-3 time, each 20 grams, are taken 2 courses for the treatment of at 21 days 1 courses for the treatment of.
3, diagnostic criteria
1. sleep is slipped into the phase: time for falling asleep was above 30 minutes;
2. sleep is kept: the number of times of awakening night surpass 2 times or morning early awakening;
3. sleep quality: many bad dreams;
4. be less than 6 hours total length of one's sleep;
5. residual effect in the daytime: feel dizzy inferior morning, lassitude, drowsiness, weak etc.
4, criterion of therapeutical effect
Produce effects: the tcm clinical practice symptom disappears substantially or obviously changes;
Effectively: tcm clinical practice symptom, sign all take a favorable turn;
Invalid: tcm clinical practice symptom, sign all do not have obvious improvement;
5, therapeutic outcome
| Disease | The treatment number | Produce effects | Effectively | Invalid | Total effective rate |
| Insomnia | 60 examples | 55 examples | 4 examples | 1 example | 98% |
6, conclusion
60 routine patients take 2 courses for the treatment of of medicated wine of the present invention (according to embodiment 1 method preparation) respectively, and the result shows that Cure for insomnia total effective rate of the present invention is 98%.
Experimental example two, model case
1, old XX, the woman, 30 years old, Yuncheng, Shanxi people from city, the dream multimass was bad when the long-term thought of readme on April 18 had the pressure sleep in 2011, through taking medicated wine of the present invention (according to the preparation of embodiment 1 method, every day 2-3 time, each 20 grams) sleep obviously improves after 5 days, and sleep recovers normal condition after one month.
2, warm X, woman, 28 years old, the Yuncheng, Shanxi city, it is not enough always to sleep behind the living complete primary school child of readme on February 21st, 2012, causes susceptible to lose temper due to restlessness for a long time, the black eye cyan is taken capsule of the present invention (according to the preparation of embodiment 2 methods) and was clearly better in back 1 month, is almost recovered after 2 months.
3 XX, woman, 31 years old, the Yuncheng, Shanxi city, readme long-term work on the 16th May in 2011 life stress causes digesting bad greatly, the sleep dreaming often and waking easily, poor sleeping quality is taken tablet of the present invention (according to the preparation of embodiment 3 methods) and was clearly better recovery from illness after 3 months in back 1 month.
Following embodiment all can realize the effect of above-mentioned experimental example.
Embodiment 1 medicated wine
Massa Medicata Fermentata 5g Radix Cyathulae 10g Radix Adenophorae (Radix Glehniae) 20g
Radix Paeoniae Alba 15g Radix Rehmanniae Preparata 10g Rhizoma Et Radix Notopterygii 5g
Fructus Anisi Stellati 10g Semen Ziziphi Spinosae 30g Radix Peucedani 10g
Cortex Cinnamomi 10g Fructus Lycii 10g Radix Clematidis 10g
Radix Glycyrrhizae Poria cum Radix Pini 10g 10g Garcinia mangostana 10g
Spica Prunellae 10g Fructus Chaenomelis 15g Cortex Eucommiae 10g
Rhizoma Chuanxiong 15g Radix Gentianae Macrophyllae 10g Radix Saposhnikoviae 15g
Radix Angelicae Pubescentis 5g Fructus Jujubae 10g Rhizoma Zingiberis Recens 10g
Said medicine adds Chinese liquor 1500g soaked 21 days, made medicated wine.Every day 2-3 time, each 20 grams.
Embodiment 2 capsules
Massa Medicata Fermentata 4kg Radix Cyathulae 13kg Radix Adenophorae (Radix Glehniae) 12kg
Radix Paeoniae Alba 21kg Radix Rehmanniae Preparata 7kg Rhizoma Et Radix Notopterygii 6kg
Fructus Anisi Stellati 7kg Semen Ziziphi Spinosae 43kg Radix Peucedani 7kg
Cortex Cinnamomi 13kg Fructus Lycii 7kg Radix Clematidis 13kg
Radix Glycyrrhizae Poria cum Radix Pini 7kg 13kg Garcinia mangostana 7kg
Spica Prunellae 13kg Fructus Chaenomelis 9kg Cortex Eucommiae 13kg
Rhizoma Chuanxiong 9kg Radix Gentianae Macrophyllae 13kg Radix Saposhnikoviae 9kg
Radix Angelicae Pubescentis 6kg Fructus Jujubae 7kg Rhizoma Zingiberis Recens 13kg
Said medicine is added conventional adjuvant according to common process make capsule.
Embodiment 3 tablets
Massa Medicata Fermentata 6kg Radix Cyathulae 7kg Radix Adenophorae (Radix Glehniae) 28kg
Radix Paeoniae Alba 9kg Radix Rehmanniae Preparata 13kg Rhizoma Et Radix Notopterygii 4kg
Fructus Anisi Stellati 13kg Semen Ziziphi Spinosae 17kg Radix Peucedani 13kg
Cortex Cinnamomi 7kg Fructus Lycii 13kg Radix Clematidis 7kg
Radix Glycyrrhizae Poria cum Radix Pini 13kg 7kg Garcinia mangostana 13kg
Spica Prunellae 7kg Fructus Chaenomelis 21kg Cortex Eucommiae 7kg
Rhizoma Chuanxiong 21kg Radix Gentianae Macrophyllae 7kg Radix Saposhnikoviae 21kg
Radix Angelicae Pubescentis 4kg Fructus Jujubae 13kg Rhizoma Zingiberis Recens 7kg
Said medicine is added conventional adjuvant according to common process make tablet.
Embodiment 4 granules
Massa Medicata Fermentata 5kg Radix Cyathulae 10kg Radix Adenophorae (Radix Glehniae) 20kg
Radix Paeoniae Alba 15kg Radix Rehmanniae Preparata 10kg Rhizoma Et Radix Notopterygii 5kg
Fructus Anisi Stellati 10kg Semen Ziziphi Spinosae 30kg Radix Peucedani 10kg
Cortex Cinnamomi 10kg Fructus Lycii 10kg Radix Clematidis 10kg
Radix Glycyrrhizae Poria cum Radix Pini 10kg 10kg Garcinia mangostana 10kg
Spica Prunellae 10kg Fructus Chaenomelis 15kg Cortex Eucommiae 10kg
Rhizoma Chuanxiong 15kg Radix Gentianae Macrophyllae 10kg Radix Saposhnikoviae 15kg
Radix Angelicae Pubescentis 5kg Fructus Jujubae 10kg Rhizoma Zingiberis Recens 10kg
Said medicine is added conventional adjuvant according to common process make granule.
Embodiment 5 oral liquids
Massa Medicata Fermentata 4kg Radix Cyathulae 13kg Radix Adenophorae (Radix Glehniae) 12kg
Radix Paeoniae Alba 21kg Radix Rehmanniae Preparata 7kg Rhizoma Et Radix Notopterygii 6kg
Fructus Anisi Stellati 7kg Semen Ziziphi Spinosae 43kg Radix Peucedani 7kg
Cortex Cinnamomi 13kg Fructus Lycii 7kg Radix Clematidis 13kg
Radix Glycyrrhizae Poria cum Radix Pini 7kg 13kg Garcinia mangostana 7kg
Spica Prunellae 13kg Fructus Chaenomelis 9kg Cortex Eucommiae 13kg
Rhizoma Chuanxiong 9kg Radix Gentianae Macrophyllae 13kg Radix Saposhnikoviae 9kg
Radix Angelicae Pubescentis 6kg Fructus Jujubae 7kg Rhizoma Zingiberis Recens 13kg
Said medicine is added conventional adjuvant according to common process make oral liquid.
Embodiment 6 pills
Massa Medicata Fermentata 6kg Radix Cyathulae 7kg Radix Adenophorae (Radix Glehniae) 28kg
Radix Paeoniae Alba 9kg Radix Rehmanniae Preparata 13kg Rhizoma Et Radix Notopterygii 4kg
Fructus Anisi Stellati 13kg Semen Ziziphi Spinosae 17kg Radix Peucedani 13kg
Cortex Cinnamomi 7kg Fructus Lycii 13kg Radix Clematidis 7kg
Radix Glycyrrhizae Poria cum Radix Pini 13kg 7kg Garcinia mangostana 13kg
Spica Prunellae 7kg Fructus Chaenomelis 21kg Cortex Eucommiae 7kg
Rhizoma Chuanxiong 21kg Radix Gentianae Macrophyllae 7kg Radix Saposhnikoviae 21kg
Radix Angelicae Pubescentis 4kg Fructus Jujubae 13kg Rhizoma Zingiberis Recens 7kg
Said medicine is added conventional adjuvant according to common process make pill.
Claims (6)
1. the pharmaceutical composition of a Cure for insomnia is characterized in that, the crude drug of said composition consists of:
Massa Medicata Fermentata 2-8 weight portion Radix Cyathulae 5-15 weight portion Radix Adenophorae (Radix Glehniae) 10-30 weight portion
Radix Paeoniae Alba 7-23 weight portion Radix Rehmanniae Preparata 5-15 weight portion Rhizoma Et Radix Notopterygii 2-8 weight portion
Fructus Anisi Stellati 5-15 weight portion Semen Ziziphi Spinosae 15-45 weight portion Radix Peucedani 5-15 weight portion
Cortex Cinnamomi 5-15 weight portion Fructus Lycii 5-15 weight portion Radix Clematidis 5-15 weight portion
Radix Glycyrrhizae 5-15 weight portion Poria cum Radix Pini 5-15 weight portion Garcinia mangostana 5-15 weight portion
Spica Prunellae 5-15 weight portion Fructus Chaenomelis 7-23 weight portion Cortex Eucommiae 5-15 weight portion
Rhizoma Chuanxiong 7-23 weight portion Radix Gentianae Macrophyllae 5-15 weight portion Radix Saposhnikoviae 7-23 weight portion
Radix Angelicae Pubescentis 2-8 weight portion Fructus Jujubae 5-15 weight portion Rhizoma Zingiberis Recens 5-15 weight portion.
2. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of said composition consists of:
Massa Medicata Fermentata 5 weight portion Radix Cyathulaes 10 weight portion Radix Adenophorae (Radix Glehniae) 20 weight portions
The Radix Paeoniae Alba 15 weight portion Radix Rehmanniaes Preparata 10 weight portion Rhizoma Et Radix Notopterygiis 5 weight portions
Fructus Anisi Stellati 10 weight portion Semen Ziziphi Spinosaes 30 weight portion Radix Peucedanis 10 weight portions
Cortex Cinnamomi 10 weight portion Fructus Lyciis 10 weight portion Radix Clematidis 10 weight portions
Radix Glycyrrhizae 10 weight portion Poria cum Radix Pinis 10 weight portion Garcinia mangostana 10 weight portions
The Spica Prunellae 10 weight portion Fructus Chaenomeliss 15 weight portion Cortexs Eucommiae 10 weight portions
Rhizoma Chuanxiong 15 weight portion Radix Gentianae Macrophyllae 10 weight portion Radix Saposhnikoviaes 15 weight portions
Radix Angelicae Pubescentis 5 weight portion Fructus Jujubaes 10 weight portion Rhizoma Zingiberis Recenss 10 weight portions.
3. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of said composition consists of:
Massa Medicata Fermentata 4 weight portion Radix Cyathulaes 13 weight portion Radix Adenophorae (Radix Glehniae) 12 weight portions
The Radix Paeoniae Alba 21 weight portion Radix Rehmanniaes Preparata 7 weight portion Rhizoma Et Radix Notopterygiis 6 weight portions
Fructus Anisi Stellati 7 weight portion Semen Ziziphi Spinosaes 43 weight portion Radix Peucedanis 7 weight portions
Cortex Cinnamomi 13 weight portion Fructus Lyciis 7 weight portion Radix Clematidis 13 weight portions
Radix Glycyrrhizae 7 weight portion Poria cum Radix Pinis 13 weight portion Garcinia mangostana 7 weight portions
The Spica Prunellae 13 weight portion Fructus Chaenomeliss 9 weight portion Cortexs Eucommiae 13 weight portions
Rhizoma Chuanxiong 9 weight portion Radix Gentianae Macrophyllae 13 weight portion Radix Saposhnikoviaes 9 weight portions
Radix Angelicae Pubescentis 6 weight portion Fructus Jujubaes 7 weight portion Rhizoma Zingiberis Recenss 13 weight portions.
4. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of said composition consists of:
Massa Medicata Fermentata 6 weight portion Radix Cyathulaes 7 weight portion Radix Adenophorae (Radix Glehniae) 28 weight portions
The Radix Paeoniae Alba 9 weight portion Radix Rehmanniaes Preparata 13 weight portion Rhizoma Et Radix Notopterygiis 4 weight portions
Fructus Anisi Stellati 13 weight portion Semen Ziziphi Spinosaes 17 weight portion Radix Peucedanis 13 weight portions
Cortex Cinnamomi 7 weight portion Fructus Lyciis 13 weight portion Radix Clematidis 7 weight portions
Radix Glycyrrhizae 13 weight portion Poria cum Radix Pinis 7 weight portion Garcinia mangostana 13 weight portions
The Spica Prunellae 7 weight portion Fructus Chaenomeliss 21 weight portion Cortexs Eucommiae 7 weight portions
Rhizoma Chuanxiong 21 weight portion Radix Gentianae Macrophyllae 7 weight portion Radix Saposhnikoviaes 21 weight portions
Radix Angelicae Pubescentis 4 weight portion Fructus Jujubaes 13 weight portion Rhizoma Zingiberis Recenss 7 weight portions.
5. as the described pharmaceutical composition of one of claim 1-4, it is characterized in that said composition adds conventional adjuvant according to common process and makes the medicated wine of clinical acceptance, tablet, capsule, granule, pill, powder, decoction or oral liquid.
6. as the application of the described pharmaceutical composition of one of claim 1-4 in the medicine of preparation Cure for insomnia.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210168022 CN102657836B (en) | 2012-05-28 | 2012-05-28 | Medicine composition used for treating insomnia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210168022 CN102657836B (en) | 2012-05-28 | 2012-05-28 | Medicine composition used for treating insomnia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102657836A CN102657836A (en) | 2012-09-12 |
| CN102657836B true CN102657836B (en) | 2013-10-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210168022 Expired - Fee Related CN102657836B (en) | 2012-05-28 | 2012-05-28 | Medicine composition used for treating insomnia |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103330925B (en) * | 2013-06-26 | 2015-08-26 | 孙桂侠 | A kind of medicine for the treatment of chorea minor and preparation method thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4317868C2 (en) * | 1993-05-28 | 1996-04-18 | Arrowdean Ltd | Novel anxiolytic |
| CN1133736A (en) * | 1995-04-19 | 1996-10-23 | 李溥 | Medicinal liquor and its preparing process |
| CN1164419A (en) * | 1996-05-08 | 1997-11-12 | 王广平 | Multi-effect health-care medicinal wine and its preparing method |
| CN101961192B (en) * | 2010-10-27 | 2012-05-09 | 江苏红豆杉生物科技有限公司 | Chinese medicinal health-care pillow |
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Granted publication date: 20131002 Termination date: 20140528 |