CN105456857A

CN105456857A - Traditional Chinese medicine preparation for treating testudinate drug-induced liver diseases and preparation method thereof

Info

Publication number: CN105456857A
Application number: CN201510960312.1A
Authority: CN
Inventors: 张莘蔓
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-21
Filing date: 2015-12-21
Publication date: 2016-04-06

Abstract

The invention discloses a traditional Chinese medicine preparation for treating testudinate drug-induced liver diseases, and belongs to the technical field of processing of testudinate feed additives. The traditional Chinese medicine preparation comprises the following raw materials of Chinese thorowax root, mistletoe, fruit of Chinese wolfberry, Chinese mugwort leaf, Radix Polygoni Multiflori, plantain seed, tuber of stemona, herba aristolochiae, Rhizoma Coptidis, dahurian patrinia herb, Chinese parsnip root, root of kudzuvine, purslane herb, mint, herba Siegesbeckiae, Chinese pennisetum, bark of eucommia, garlic, lily bulb, officinal magnolia bark, heartleaf houttuynia herb, Japanese buttercup herb, prepared kusnezoff monkshood root, grassleaf sweelflag rhizome and resina ferulae. The traditional Chinese medicine preparation is prepared by the following steps of extracting of a medicine liquor, concentrating, drying, crushing, sieving, sterilizing, and the like. The traditional Chinese medicine preparation has the advantages that the effects of multiple traditional Chinese medicines are integrated, the functions of protecting livers, resisting bacteria and eliminating inflammation, enhancing body immunity and the like are realized, the effect of testudinate absorbing the traditional Chinese medicine preparation is good, the testudinate immunity and anti-stress capability are improved, the death rate of the testudinate drug-induced liver diseases is reduced, and the curative rate of the testudinate drug-induced liver diseases is improved.

Description

A kind ofly treat Chinese medicine preparation of testudinate drug induccd hepatopathy and preparation method thereof

Technical field

The invention belongs to Terrapin feed additive processing technique field, be specifically related to a kind ofly treat Chinese medicine preparation of testudinate drug induccd hepatopathy and preparation method thereof.

Background technology

Terrapin has edible, medicinal and the value such as to view and admire.Terrapin is always considered to senior delicacies, is the Important Economic kind of China's aquaculture, is again excellent tonic product simultaneously, has certain effect to cancer and to raising human motion function.Along with people's life and the raising of level of consumption, the demand of people to testudinate is more and more higher, only leans on wild testudinate resource, can not meet growing consumer need far away.Under the driving of the market demand and radical economic benefit at home, increasing raiser starts to develop artificial cultivation testudinate.

The long-term chemical drugs that adds in feedstuff carries out initiatively diseases prevention or applies the main cause that the medicine of hepatic injury and inappropriate medication are testudinate generation drug induccd hepatopathys when treating certain disease of testudinate.Metabolism main after in testudinate body, removing toxic substances place is entered because liver is medicine.Particularly from digestive tract and pylic medicine, the impact of liver is even more important.Drug induccd hepatopathy is caused by following factor: one is toxic action, the drug anaphylaxis of medicine to liver; Two is medicine impacts on bilirubin metabolism; Three is drug-induced haemolysis and accumulate poisoning etc.Particularly inappropriate and with two or more medicine time, there will be summation action, thus make toxicity strengthen cause hepatopathy.The common Western medicine of general easily attractive hepatitis due to medicine has tetracycline, benzylpencilline, erythromycin, chloromycetin, sulfonamides, furans and estrogen and androgen etc.Chinese medicine has Rhizoma Dioscoreae Bulbiferae, Fructus Xanthii, Galla Chinensis etc.

At present, most professional raising farmer adopts the premix material of other Fish to feed when Terrapin raising, long-term medicine and the inappropriate medication adding chemical drugs and carry out initiatively diseases prevention or apply hepatic injury when treating certain disease of testudinate in feedstuff, testudinate is easily made to suffer from drug induccd hepatopathy, cause testudinate mortality rate high, cause raiser to suffer huge loss.Therefore, a kind of feed additive being used for the treatment of testudinate drug induccd hepatopathy of necessary research and development.

Summary of the invention

The invention provides and a kind ofly treat Chinese medicine preparation of testudinate drug induccd hepatopathy and preparation method thereof, suffer from the problems such as drug induccd hepatopathy causes mortality rate high, and survival rate is low, and cultivation has a big risk, economic benefit is low to solve testudinate.The present invention combines plurality of Chinese effect, can play protect the liver, the effect such as anti-inflammation, enhancing human body immunity function, it is effective that testudinate absorbs Chinese medicine preparation of the present invention, can strengthen immunity and the anti-stress ability of testudinate, effective reduction testudinate suffers from the mortality rate of drug induccd hepatopathy and improves the cure rate of testudinate trouble drug induccd hepatopathy.

For solving above technical problem, the present invention by the following technical solutions:

A kind of Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy, in units of weight portion, comprise following raw material: Radix Bupleuri 20-30 part, Herba Visci 20-30 part, Fructus Lycii 20-30 part, Folium Artemisiae Argyi 20-30 part, Radix Polygoni Multiflori 20-30 part, Semen Plantaginis 12-20 part, Radix Stemonae 12-20 part, Herba Aristolochiae 12-20 part, Rhizoma Coptidis 12-20 part, Herba Patriniae 12-20 part, Radix Saposhnikoviae 8-16 part, Radix Puerariae 8-16 part, Herba Portulacae 8-16 part, Herba Menthae 8-16 part, Herba Siegesbeckiae 8-16 part, gold silver grass 6-12 part, Cortex Eucommiae 6-12 part, Bulbus Allii 6-12 part, Bulbus Lilii 6-12 part, Cortex Magnoliae Officinalis 6-12 part, Herba Houttuyniae 3-6 part, Herba Ranunculi Japonici 3-6 part, Radix Aconiti Kusnezoffii Preparata 3-6 part, Rhizoma Acori Graminei 3-6 part, Resina Ferulae 3-6 part.

Preferably, the Chinese medicine preparation of described treatment testudinate drug induccd hepatopathy, in units of weight portion, comprise following raw material: Radix Bupleuri 22-28 part, Herba Visci 22-28 part, Fructus Lycii 22-28 part, Folium Artemisiae Argyi 22-28 part, Radix Polygoni Multiflori 22-28 part, Semen Plantaginis 14-18 part, Radix Stemonae 14-18 part, Herba Aristolochiae 14-18 part, Rhizoma Coptidis 14-18 part, Herba Patriniae 14-18 part, Radix Saposhnikoviae 10-14 part, Radix Puerariae 10-14 part, Herba Portulacae 10-14 part, Herba Menthae 10-14 part, Herba Siegesbeckiae 10-14 part, gold silver grass 8-10 part, Cortex Eucommiae 8-10 part, Bulbus Allii 8-10 part, Bulbus Lilii 8-10 part, Cortex Magnoliae Officinalis 8-10 part, Herba Houttuyniae 4-5 part, Herba Ranunculi Japonici 4-5 part, Radix Aconiti Kusnezoffii Preparata 4-5 part, Rhizoma Acori Graminei 4-5 part, Resina Ferulae 4-5 part.

Preferably, the Chinese medicine preparation of described treatment testudinate drug induccd hepatopathy, in units of weight portion, comprise following raw material: Radix Bupleuri 25 parts, Herba Visci 25 parts, Fructus Lycii 25 parts, Folium Artemisiae Argyi 25 parts, Radix Polygoni Multiflori 25 parts, Semen Plantaginis 15 parts, the Radix Stemonae 15 parts, Herba Aristolochiae 15 parts, Rhizoma Coptidis 15 parts, Herba Patriniae 15 parts, Radix Saposhnikoviae 12 parts, Radix Puerariae 12 parts, Herba Portulacae 12 parts, Herba Menthae 12 parts, Herba Siegesbeckiae 12 parts, gold silver grass 8 parts, the Cortex Eucommiae 8 parts, 8 parts, Bulbus Allii, Bulbus Lilii 8 parts, Cortex Magnoliae Officinalis 8 parts, Herba Houttuyniae 5 parts, Herba Ranunculi Japonici 5 parts, Radix Aconiti Kusnezoffii Preparata 5 parts, Rhizoma Acori Graminei 5 parts, Resina Ferulae 5 parts.

The present invention also provides a kind of preparation method for the treatment of the Chinese medicine preparation of testudinate drug induccd hepatopathy, comprises the following steps:

S1: by Radix Bupleuri, Herba Visci, Fructus Lycii, Folium Artemisiae Argyi, Radix Polygoni Multiflori, Semen Plantaginis, the Radix Stemonae, Herba Aristolochiae, Rhizoma Coptidis, Herba Patriniae, Radix Saposhnikoviae, Radix Puerariae, Herba Portulacae, Herba Menthae, Herba Siegesbeckiae, gold silver grass, the Cortex Eucommiae, Bulbus Allii, Bulbus Lilii, Cortex Magnoliae Officinalis, Herba Houttuyniae, Herba Ranunculi Japonici, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, Resina Ferulae co-grinding, obtain mixture A, mixture A is joined in organic solvent, under ultrasonic assistant extraction method, extracts medicinal liquid;

S2: by medical filtration obtained for step S1, concentrate, obtain mixture B;

S3: mixture B obtained for step S2 is dry, pulverize, sieve, sterilizing, the Chinese medicine preparation of obtained treatment testudinate drug induccd hepatopathy.

Preferably, organic solvent described in step S1 comprises one or more in ethanol, butanone, trichloroethane, Carbon bisulfide.

Preferably, the condition of the extraction method of ultrasonic assistant described in step S1 extraction medicinal liquid is: ultrasonic power is 150-170W, and organic solvent concentration is 50%-80%, and Extracting temperature is 50-70 DEG C, and extraction time is 30-50min.

Preferably, step S2 herb liquid filters, and is concentrated into water content 10%-22%.

Preferably, in step S3, mixture B is dried to water content 4%-6% at 95-105 DEG C.

Preferably, the condition of sieving in step S3 is: cross 120-320 mesh sieve.

Preferably, the condition of sterilizing in step S3 is: temperature is 135-136 DEG C, and pressure is 220-230KPa, and the time is 1-2min.

Pharmacology of the present invention is as follows:

Radix Bupleuri have induce sweat bring down a fever, the effect such as dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy, the diseases such as fever caused by exogenous pathogens, alternate attack of chill and fever, malaria, hypochondriac pain due to stagnation of liverQI, mammary swelling, headache dizziness can be controlled.

Herba Visci has wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, the effect such as antiabortive, can control headache, rheumatic arthralgia, soreness of the waist and knees, frequent fetal movement, metrorrhagia through the disease such as many.

Fructus Lycii is the plant of eggplant order Solanaceae Lycium, scalable body's immunity, can effectively Tumor suppression growth and cell mutation, there is the effect of the aspect such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose, promotion hemopoietic function.

Folium Artemisiae Argyi has strong antibacterial and anti-inflammation functions, all has suppression and killing action to multiple coccus, bacillus, fungus and virus etc., is the one that in the natural plants found at present, antibacterial action is extremely strong.

Radix Polygoni Multiflori has tonifying liver, kidney tonifying, nourish blood, the effect such as to dispel the wind, and can control hepatic and renal YIN deficiency, early whitening of beard and hair, blood deficiency dizziness, soreness of the waist and knees, muscles and bones are ached, pass out semen, the disease such as metrorrhagia and leukorrhagia, chronic dysentery.

Semen Plantaginis has another name called Herba Plantaginis, five grass, and wheel dish is cold in nature, sweet in the mouth, nontoxic, has heat-clearing and toxic substances removing, diuresis eliminating dampness by diuresis, effects such as improving eyesight of eliminating the phlegm, is used for the treatment of edema, phlegm-heat cough, has loose bowels, the disease such as the puckery pain of pyretic stranguria, conjunctival congestion and swelling pain.

The Radix Stemonae has the effects such as gentle lung qi, cough-relieving, parasite killing, can control the symptoms such as cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma.

Herba Aristolochiae is bitter, warm, has a surname and to stimulate the menstrual flow tunnel, dodar stasis, soothing the liver circulation of qi promoting, only the effect such as heart stomachache.

Rhizoma Coptidis, herbaceos perennial, happiness cools, moistening part, belongs to Ranunculaceae Coptis.Rhizoma Coptidis is also a kind of conventional Chinese medicine, just the most on the books in Shennong's Herbal, because its rhizome is beaded and yellow skin, so be referred to as " Rhizoma Coptidis ".It has antibacterial, the pharmacologically active such as antitumor and arrhythmia, has effect of heat clearing and damp drying, eliminating fire and detoxication.Also there is antibacterial, blood sugar lowering, antitumor, protection gastric mucosa isoreactivity.

Herba Patriniae, with root stock and root, all herbal medicine, belongs to antipyretic and antidotal type medicine in Chinese medicine, cool in nature, acrid in the mouth, hardship.Return liver, stomach, large intestine channel, have effect of heat-clearing and toxic substances removing, removing blood stasis and expelling pus.Modern pharmacy is thought, it is containing volatile oil, Herba Patriniae Saponin and β-sterol glucose formula, have antiinflammatory, antibacterial, calm, protect the liver the effect with heart tonifying diuresis.Herba Patriniae has suppression or killing action to staphylococcus aureus, dysentery bacterium, Bacillus typhi, bacillus pyocyaneus.

Radix Saposhnikoviae has the effects such as expelling pathogenic wind from the body surface, removing damp and stopping pain, soothing the liver spasmolytic, cures mainly the diseases such as affection of exogenous wind-cold, headache stiffness of the nape, dizzy dusk puckery, anemofrigid-damp arthralgia.

Radix Puerariae has expelling pathogenic factors from muscles for reducing heat, deliver examine, the effect such as promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal, fever caused by exogenous pathogens can be controlled, rigidity pain on the head and nape, measles go out the symptoms such as smooth, epidemic febrile disease is thirsty, diabetes from the beginning of, rash.

Herba Portulacae is cold in nature, and sweet in the mouth acid, has heat-clearing and toxic substances removing, diuretic dries, loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effects such as hemostasis removing heat from blood, have stronger inhibitory action to dysentery bacterium, Bacillus typhi and escherichia coli, cure mainly dysentery, enteritis, hepatitis, nephritis, puerperal, metrorrhagia, had blood in stool, the diseases such as mastitis.

Herba Menthae is labiate, and Herba Menthae has the effect stimulating nervus centralis, and acting on skin has bright sense and creeping chill simultaneously, and it has again the effect of suppression and paralysis to sensory nerve ending; Herba Menthae has desensitization, antiinflammatory and antibacterial effect to mosquito bite skin; Also obvious cough-relieving, antiinflammatory and bacteriostasis is had to upper respiratory tract infection; Hemorrhoid, anal fissure are had to the effect of reducing swelling and alleviating pain, antiphlogistic antibacterial; Excited effect is had for taste nerve and olfactory nerves; Refrigerant throat-moistening specific to Herba Menthae and the pleasant abnormal smells from the patient of fragrance is covered up and improve some has abnormal flavour and be difficult to senses of discomfort of the medicine swallowed.

Herba Siegesbeckiae has the effect such as wind-damp dispelling, relieving rigidity of muscles and joints, can control the diseases such as quadriplegia, bones and muscles pain, weakness of the waist and knees, malaria, acute hepatitis, hypertension, furuncle swelling toxin.

Gold silver grass has the effect such as heat-clearing and toxic substances removing, dispelling wind and heat pathogens, cures mainly red and swollen heat pain, malaria, affection due to external wind and heat, epidemic febrile disease from the beginning of, the symptom such as toxic-heat and blood stasis, summer-heat excessive thirst, laryngopharynx swelling and pain.

The Cortex Eucommiae has liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through the effect such as antiabortive, can control the symptoms such as cough, soreness of waist and knee joint, sexual impotence, seminal emission, frequent micturition.

Bulbus Allii, herbaceos perennial, Liliaceae Allium.In Bulbus Allii, sulfur-containing compound has strong antibacterial and anti-inflammation functions, all has suppression and killing action to multiple coccus, bacillus, fungus and virus etc., is the one that in the natural plants found at present, antibacterial action is the strongest; The elements such as the germanium in Bulbus Allii and selenium can the growth of inhibition tumor cell and cancerous cell, and experiment finds, the crowd that cancer incidence is minimum is exactly the crowd that in blood, selenium content is the highest.National Cancer tissue is thought, in the plant of the anticancer potentiality of whole world most, what rank first is Bulbus Allii; Bulbus Allii can effectively suppress and kill the bacterial viruses such as the helicobacter pylori causing gastroenteropathy, removes the intestines and stomach noxious substance, stimulating gastrointestinal mucosa, promotes appetite, accelerates digestion; Containing a kind of Capsaicin being " allyl sulfides " in Bulbus Allii, there is good killing action to pathogen and parasite, can preventing cold, alleviate fever, cough, have sore throat and the cold symptoms such as nasal obstruction.

Bulbus Lilii has the effects such as removing toxic substances, the stomach invigorating of reason spleen, dampness removing removing food stagnancy, mind tranquilizing and the heart calming, blood circulation promoting, cures mainly the symptoms such as chronic cough, hemoptysis, fidgets due to deficiency palpitation with fear.

The ether of Cortex Magnoliae Officinalis and methanolic extract have strong antibacterial action to cariogenic bacteria Streptococcus mutans (Streptococusmatuans), and its Antibacterial Constituents is defined as Magnolol and Honokiol.Both are 6.3 μ g/ml to the minimum inhibitory concentration (MIC) of Streptococcus mutans, and its antibacterial action (to Streptococcus mutans) is stronger than berberine.The first deduction of Cortex Magnoliae Officinalis divides magnocurarine and Cortex Magnoliae Officinalis volatile oil saturated aqueous solution to have certain bacteriostasis to staphylococcus aureus, sarcina and bacillus subtilis, and Cortex Magnoliae Officinalis also has antibacterial activity to Diplococcus pneumoniae and dysentery bacterium.

Herba Houttuyniae has the effect such as heat-clearing and toxic substances removing, inducing diuresis to remove edema, can cure cold, pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, the symptom such as leucorrhea.

Herba Ranunculi Japonici has the effect such as wind-damp dispelling, removing toxic substances and promoting subsidence of swelling, can treating malaria disease, rheumatic arthralgia, the arthroncus of knee, malignant boil carbuncle, pain do not burst, the disease such as jaundice.

Radix Aconiti Kusnezoffii Preparata have dispel the wind, dehumidify, cold expelling, the effect such as pain relieving, can treating malaria disease, anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type have a pain, the disease such as narcotic analgesic.

Rhizoma Acori Graminei has waking up the patient from unconsciousness by dissipating phlegm, removing dampness circulation of qi promoting, effects such as sharp numbness, reducing swelling and alleviating pain of dispeling the wind, and can control the diseases such as calentura coma, syncope due to accumulation of phlegm, forgetful, tinnitus, deafness, abdominal distention, fasting dysentery, rheumatic arthralgia, traumatic injury.

The effects such as having of Resina Ferulae disease removing food stagnancy, parasite killing, preventing the attack (or recurrence) of malaria, can control the diseases such as food stagnation, distension and fullness of the chest and abdomen, cold type of pain, malaria, dysentery.

The present invention has following beneficial effect:

(1) the present invention be combine Radix Bupleuri, Herba Visci, Fructus Lycii, Folium Artemisiae Argyi, Radix Polygoni Multiflori, Semen Plantaginis, the Radix Stemonae, Herba Aristolochiae, Rhizoma Coptidis, Herba Patriniae, Radix Saposhnikoviae, Radix Puerariae, Herba Portulacae, Herba Menthae, Herba Siegesbeckiae, gold silver grass, the Cortex Eucommiae, Bulbus Allii, Bulbus Lilii, Cortex Magnoliae Officinalis, Herba Houttuyniae, Herba Ranunculi Japonici, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, Resina Ferulae plurality of Chinese effect can play protect the liver, the effect such as anti-inflammation, enhancing human body immunity function, be a kind of efficient, safe, natural Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy;

(2) testudinate to absorb Chinese medicine preparation of the present invention effective, immunity and the anti-stress ability of testudinate can be strengthened, reduce the mortality rate that testudinate suffers from drug induccd hepatopathy and reach more than 30%, improve the cure rate that testudinate suffers from drug induccd hepatopathy and reach more than 47%;

(3) the present invention adopts ultrasonic assistant extraction method to extract Effective Component of Chinese Medicine, and extraction efficiency is fast, and extraction ratio is high;

(4) Chinese medicine preparation of the present invention carries out sterilizing at high temperature under high pressure, and the time is short, effective, and the Chinese medicine preparation holding time is long;

(5) Chinese medicine preparation preparation method of the present invention is simple to operate, and production cost is low, is conducive to applying.

Detailed description of the invention

Be specifically described below in conjunction with specific embodiment.

Embodiment 1

A kind of Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy, in units of weight portion, comprise following raw material: Radix Bupleuri 20 parts, Herba Visci 20 parts, Fructus Lycii 20 parts, Folium Artemisiae Argyi 20 parts, Radix Polygoni Multiflori 20 parts, Semen Plantaginis 12 parts, the Radix Stemonae 12 parts, Herba Aristolochiae 12 parts, Rhizoma Coptidis 12 parts, Herba Patriniae 12 parts, Radix Saposhnikoviae 8 parts, Radix Puerariae 8 parts, Herba Portulacae 8 parts, Herba Menthae 8 parts, Herba Siegesbeckiae 8 parts, gold silver grass 6 parts, the Cortex Eucommiae 6 parts, 6 parts, Bulbus Allii, Bulbus Lilii 6 parts, Cortex Magnoliae Officinalis 6 parts, Herba Houttuyniae 3 parts, Herba Ranunculi Japonici 3 parts, Radix Aconiti Kusnezoffii Preparata 3 parts, Rhizoma Acori Graminei 3 parts, Resina Ferulae 3 parts.

The preparation method of the Chinese medicine preparation of above-mentioned treatment testudinate drug induccd hepatopathy, comprises the following steps:

S1: by Radix Bupleuri, Herba Visci, Fructus Lycii, Folium Artemisiae Argyi, Radix Polygoni Multiflori, Semen Plantaginis, the Radix Stemonae, Herba Aristolochiae, Rhizoma Coptidis, Herba Patriniae, Radix Saposhnikoviae, Radix Puerariae, Herba Portulacae, Herba Menthae, Herba Siegesbeckiae, gold silver grass, the Cortex Eucommiae, Bulbus Allii, Bulbus Lilii, Cortex Magnoliae Officinalis, Herba Houttuyniae, Herba Ranunculi Japonici, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, Resina Ferulae co-grinding, obtain mixture A, mixture A is joined in ethanol, medicinal liquid is extracted under ultrasonic assistant extraction method, condition is: ultrasonic power is 150W, concentration of alcohol is 50%, Extracting temperature is 50 DEG C, and extraction time is 50min;

S2: the medical filtration obtained by step S1, is concentrated into water content 10%, obtains mixture B;

S3: the mixture B that step S2 is obtained is dried to water content 6% at 95 DEG C, then pulverizes, cross 120 mesh sieve, gained powder is 135 DEG C in temperature, and pressure is sterilizing 2min under 220KPa, the Chinese medicine preparation of obtained treatment testudinate drug induccd hepatopathy.

Embodiment 2

A kind of Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy, in units of weight portion, comprise following raw material: Radix Bupleuri 30 parts, Herba Visci 30 parts, Fructus Lycii 30 parts, Folium Artemisiae Argyi 30 parts, Radix Polygoni Multiflori 30 parts, Semen Plantaginis 20 parts, the Radix Stemonae 20 parts, Herba Aristolochiae 20 parts, Rhizoma Coptidis 20 parts, Herba Patriniae 20 parts, Radix Saposhnikoviae 16 parts, Radix Puerariae 16 parts, Herba Portulacae 16 parts, Herba Menthae 16 parts, Herba Siegesbeckiae 16 parts, gold silver grass 12 parts, the Cortex Eucommiae 12 parts, 12 parts, Bulbus Allii, Bulbus Lilii 12 parts, Cortex Magnoliae Officinalis 12 parts, Herba Houttuyniae 6 parts, Herba Ranunculi Japonici 6 parts, Radix Aconiti Kusnezoffii Preparata 6 parts, Rhizoma Acori Graminei 6 parts, Resina Ferulae 6 parts.

S1: by Radix Bupleuri, Herba Visci, Fructus Lycii, Folium Artemisiae Argyi, Radix Polygoni Multiflori, Semen Plantaginis, the Radix Stemonae, Herba Aristolochiae, Rhizoma Coptidis, Herba Patriniae, Radix Saposhnikoviae, Radix Puerariae, Herba Portulacae, Herba Menthae, Herba Siegesbeckiae, gold silver grass, the Cortex Eucommiae, Bulbus Allii, Bulbus Lilii, Cortex Magnoliae Officinalis, Herba Houttuyniae, Herba Ranunculi Japonici, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, Resina Ferulae co-grinding, obtain mixture A, mixture A is joined in butanone, medicinal liquid is extracted under ultrasonic assistant extraction method, condition is: ultrasonic power is 170W, butanone concentration is 80%, Extracting temperature is 70 DEG C, and extraction time is 30min;

S2: the medical filtration obtained by step S1, is concentrated into water content 22%, obtains mixture B;

S3: the mixture B that step S2 is obtained is dried to water content 4%% at 105 DEG C, then pulverizes, cross 320 mesh sieve, gained powder is 136 DEG C in temperature, and pressure is sterilizing 1min under 230KPa, the Chinese medicine preparation of obtained treatment testudinate drug induccd hepatopathy.

Embodiment 3

A kind of Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy, in units of weight portion, comprise following raw material: Radix Bupleuri 25 parts, Herba Visci 25 parts, Fructus Lycii 25 parts, Folium Artemisiae Argyi 25 parts, Radix Polygoni Multiflori 25 parts, Semen Plantaginis 15 parts, the Radix Stemonae 15 parts, Herba Aristolochiae 15 parts, Rhizoma Coptidis 15 parts, Herba Patriniae 15 parts, Radix Saposhnikoviae 12 parts, Radix Puerariae 12 parts, Herba Portulacae 12 parts, Herba Menthae 12 parts, Herba Siegesbeckiae 12 parts, gold silver grass 8 parts, the Cortex Eucommiae 8 parts, 8 parts, Bulbus Allii, Bulbus Lilii 8 parts, Cortex Magnoliae Officinalis 8 parts, Herba Houttuyniae 5 parts, Herba Ranunculi Japonici 5 parts, Radix Aconiti Kusnezoffii Preparata 5 parts, Rhizoma Acori Graminei 5 parts, Resina Ferulae 5 parts.

S1: by Radix Bupleuri, Herba Visci, Fructus Lycii, Folium Artemisiae Argyi, Radix Polygoni Multiflori, Semen Plantaginis, the Radix Stemonae, Herba Aristolochiae, Rhizoma Coptidis, Herba Patriniae, Radix Saposhnikoviae, Radix Puerariae, Herba Portulacae, Herba Menthae, Herba Siegesbeckiae, gold silver grass, the Cortex Eucommiae, Bulbus Allii, Bulbus Lilii, Cortex Magnoliae Officinalis, Herba Houttuyniae, Herba Ranunculi Japonici, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, Resina Ferulae co-grinding, obtain mixture A, mixture A is joined in Carbon bisulfide, medicinal liquid is extracted under ultrasonic assistant extraction method, condition is: ultrasonic power is 160W, Carbon Disulfide is 65%, Extracting temperature is 60 DEG C, and extraction time is 40min;

S2: the medical filtration obtained by step S1, is concentrated into water content 15%, obtains mixture B;

S3: the mixture B that step S2 is obtained is dried to water content 5% at 100 DEG C, then pulverizes, cross 200 mesh sieve, gained powder is 136 DEG C in temperature, and pressure is sterilizing 1min under 230KPa, the Chinese medicine preparation of obtained treatment testudinate drug induccd hepatopathy.

Embodiment 4

A kind of Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy, in units of weight portion, comprise following raw material: Radix Bupleuri 22 parts, Herba Visci 22 parts, Fructus Lycii 22 parts, Folium Artemisiae Argyi 22 parts, Radix Polygoni Multiflori 22 parts, Semen Plantaginis 14 parts, the Radix Stemonae 14 parts, Herba Aristolochiae 14 parts, Rhizoma Coptidis 14 parts, Herba Patriniae 14 parts, Radix Saposhnikoviae 10 parts, Radix Puerariae 10 parts, Herba Portulacae 10 parts, Herba Menthae 10 parts, Herba Siegesbeckiae 10 parts, gold silver grass 8 parts, the Cortex Eucommiae 8 parts, 8 parts, Bulbus Allii, Bulbus Lilii 8 parts, Cortex Magnoliae Officinalis 8 parts, Herba Houttuyniae 4 parts, Herba Ranunculi Japonici 4 parts, Radix Aconiti Kusnezoffii Preparata 4 parts, Rhizoma Acori Graminei 4 parts, Resina Ferulae 4 parts.

S1: by Radix Bupleuri, Herba Visci, Fructus Lycii, Folium Artemisiae Argyi, Radix Polygoni Multiflori, Semen Plantaginis, the Radix Stemonae, Herba Aristolochiae, Rhizoma Coptidis, Herba Patriniae, Radix Saposhnikoviae, Radix Puerariae, Herba Portulacae, Herba Menthae, Herba Siegesbeckiae, gold silver grass, the Cortex Eucommiae, Bulbus Allii, Bulbus Lilii, Cortex Magnoliae Officinalis, Herba Houttuyniae, Herba Ranunculi Japonici, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, Resina Ferulae co-grinding, obtain mixture A, mixture A is joined in trichloroethane, medicinal liquid is extracted under ultrasonic assistant extraction method, condition is: ultrasonic power is 155W, trichloroethane concentration is 60%, Extracting temperature is 55 DEG C, and extraction time is 45min;

S2: the medical filtration obtained by step S1, is concentrated into water content 13%, obtains mixture B;

S3: the mixture B that step S2 is obtained is dried to water content 6% at 98 DEG C, then pulverizes, cross 180 mesh sieve, gained powder is 136 DEG C in temperature, and pressure is sterilizing 1min under 230KPa, the Chinese medicine preparation of obtained treatment testudinate drug induccd hepatopathy.

Embodiment 5

A kind of Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy, in units of weight portion, comprise following raw material: Radix Bupleuri 28 parts, Herba Visci 28 parts, Fructus Lycii 28 parts, Folium Artemisiae Argyi 28 parts, Radix Polygoni Multiflori 28 parts, Semen Plantaginis 18 parts, the Radix Stemonae 18 parts, Herba Aristolochiae 18 parts, Rhizoma Coptidis 18 parts, Herba Patriniae 18 parts, Radix Saposhnikoviae 14 parts, Radix Puerariae 14 parts, Herba Portulacae 14 parts, Herba Menthae 14 parts, Herba Siegesbeckiae 14 parts, gold silver grass 10 parts, the Cortex Eucommiae 10 parts, 10 parts, Bulbus Allii, Bulbus Lilii 10 parts, Cortex Magnoliae Officinalis 10 parts, Herba Houttuyniae 5 parts, Herba Ranunculi Japonici 5 parts, Radix Aconiti Kusnezoffii Preparata 5 parts, Rhizoma Acori Graminei 5 parts, Resina Ferulae 5 parts.

S1: by Radix Bupleuri, Herba Visci, Fructus Lycii, Folium Artemisiae Argyi, Radix Polygoni Multiflori, Semen Plantaginis, the Radix Stemonae, Herba Aristolochiae, Rhizoma Coptidis, Herba Patriniae, Radix Saposhnikoviae, Radix Puerariae, Herba Portulacae, Herba Menthae, Herba Siegesbeckiae, gold silver grass, the Cortex Eucommiae, Bulbus Allii, Bulbus Lilii, Cortex Magnoliae Officinalis, Herba Houttuyniae, Herba Ranunculi Japonici, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, Resina Ferulae co-grinding, obtain mixture A, mixture A is joined in trichloroethane and carbon disulfide mixture, medicinal liquid is extracted under ultrasonic assistant extraction method, condition is: ultrasonic power is 165W, trichloroethane and carbon disulfide mixture concentration are 75%, Extracting temperature is 65 DEG C, extraction time is 35min,

S2: the medical filtration obtained by step S1, is concentrated into water content 20%, obtains mixture B;

S3: the mixture B that step S2 is obtained is dried to water content 4%% at 102 DEG C, then pulverizes, cross 300 sieves, gained powder is 135 DEG C in temperature, and pressure is sterilizing 2min under 220KPa, the Chinese medicine preparation of obtained treatment testudinate drug induccd hepatopathy.

For checking the present invention treats the effect of the Chinese medicine preparation of testudinate drug induccd hepatopathy, by following experimental verification.

Experiment one

Select 0.22-0.3kg, specification almost consistent and make a definite diagnosis the Cyclemys trifasciata 540 of drug induccd hepatopathy, be divided into three groups at random, i.e. matched group, test group 1, test group 2, test group 3, test group 4, test group 5, often group does 3 parallel laboratory tests, often organizes Cyclemys trifasciata 30.Matched group Cyclemys trifasciata is fed the basic feedstuff be mixed with Pomacea canaliculata powder, tapioca starch, Sal, dimethyl-β-DMPT, betanin, lysine, uridylate, holder Martin polypeptide, citronellal; The Cyclemys trifasciata of test group 1 is fed and is added with the basic feedstuff of the embodiment of the present invention 1 Chinese medicine preparation; The Cyclemys trifasciata of test group 2 is fed and is added with the basic feedstuff of the embodiment of the present invention 2 Chinese medicine preparation; The Cyclemys trifasciata of test group 3 is fed and is added with the basic feedstuff of the embodiment of the present invention 3 Chinese medicine preparation; The Cyclemys trifasciata of test group 4 is fed and is added with the basic feedstuff of the embodiment of the present invention 4 Chinese medicine preparation; The Cyclemys trifasciata of test group 5 is fed and is added with the basic feedstuff of the embodiment of the present invention 5 Chinese medicine preparation.Feed continuously 10 days, feed intake every day 2 times, experimental period 10 days, mortality rate and the cure rate of Cyclemys trifasciata is calculated after terminating, computational methods: mortality rate=dead Cyclemys trifasciata number/test Cyclemys trifasciata number × 100%, cure rate=healing Cyclemys trifasciata number/test Cyclemys trifasciata number × 100%, the results are shown in following table.

	Number of elements	Mortality rate (%)	Cure rate (%)
				Matched group	90	37.78	45.56
Test group 1	90	3.33	95.56
				Test group 2	90	5.56	96.67
Test group 3	90	4.44	96.67
				Test group 4	90	4.44	96.67
Test group 5	90	4.44	96.67

As seen from the above table, test group and matched group contrast, mortality rate reduces 32.22%-34.45%, cure rate improves 50%-51.11%, illustrate that the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy of the present invention can strengthen immunity and the anti-stress ability of Cyclemys trifasciata, reduce the mortality rate that Cyclemys trifasciata suffers from drug induccd hepatopathy, improve cure rate.

Experiment two

Select 0.21-0.32kg, specification almost consistent and make a definite diagnosis the Chinese grass tortoise 540 of drug induccd hepatopathy, be divided into three groups at random, i.e. matched group, test group 1, test group 2, test group 3, test group 4, test group 5, often group does 3 parallel laboratory tests, often organizes Chinese grass tortoise 30.Matched group China grass tortoise is fed the basic feedstuff be mixed with Pomacea canaliculata powder, tapioca starch, Sal, dimethyl-β-DMPT, betanin, lysine, uridylate, holder Martin polypeptide, citronellal; The Chinese grass tortoise of test group 1 is fed and is added with the basic feedstuff of the embodiment of the present invention 1 Chinese medicine preparation; The Chinese grass tortoise of test group 2 is fed and is added with the basic feedstuff of the embodiment of the present invention 2 Chinese medicine preparation; The Chinese grass tortoise of test group 3 is fed and is added with the basic feedstuff of the embodiment of the present invention 3 Chinese medicine preparation; The Chinese grass tortoise of test group 4 is fed and is added with the basic feedstuff of the embodiment of the present invention 4 Chinese medicine preparation; The Chinese grass tortoise of test group 5 is fed and is added with the basic feedstuff of the embodiment of the present invention 5 Chinese medicine preparation.Feed continuously 10 days, feed intake every day 2 times, experimental period 10 days, mortality rate and the cure rate of Chinese grass tortoise is calculated after terminating, computational methods: mortality rate=dead Chinese grass tortoise number/test Chinese grass tortoise number × 100%, the Chinese grass tortoise number of cure rate=cure/test Chinese grass tortoise number × 100%, the results are shown in following table.

	Number of elements	Mortality rate (%)	Cure rate (%)
				Matched group	90	35.56	46.67
Test group 1	90	3.33	95.56
				Test group 2	90	3.33	96.67
Test group 3	90	4.44	96.67
				Test group 4	90	3.33	96.67
Test group 5	90	4.44	95.56

As seen from the above table, test group and matched group contrast, mortality rate reduces 31.12%-32.23%, cure rate improves 48.89%-50%, illustrate that the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy of the present invention can strengthen immunity and the anti-stress ability of Chinese grass tortoise, reduce the mortality rate that Chinese grass tortoise suffers from drug induccd hepatopathy, improve cure rate.

Experiment three

Select 0.18-0.33kg, specification almost consistent and make a definite diagnosis the yellow sand Trionyx sinensis Wiegmann 540 of drug induccd hepatopathy, be divided into three groups at random, i.e. matched group, test group 1, test group 2, test group 3, test group 4, test group 5, often group does 3 parallel laboratory tests, often organizes yellow sand Trionyx sinensis Wiegmann 30.Matched group yellow sand Trionyx sinensis Wiegmann is fed the basic feedstuff be mixed with Pomacea canaliculata powder, tapioca starch, Sal, dimethyl-β-DMPT, betanin, lysine, uridylate, holder Martin polypeptide, citronellal; The yellow sand Trionyx sinensis Wiegmann of test group 1 is fed and is added with the basic feedstuff of the embodiment of the present invention 1 Chinese medicine preparation; The yellow sand Trionyx sinensis Wiegmann of test group 2 is fed and is added with the basic feedstuff of the embodiment of the present invention 2 Chinese medicine preparation; The yellow sand Trionyx sinensis Wiegmann of test group 3 is fed and is added with the basic feedstuff of the embodiment of the present invention 3 Chinese medicine preparation; The yellow sand Trionyx sinensis Wiegmann of test group 4 is fed and is added with the basic feedstuff of the embodiment of the present invention 4 Chinese medicine preparation; The yellow sand Trionyx sinensis Wiegmann of test group 5 is fed and is added with the basic feedstuff of the embodiment of the present invention 5 Chinese medicine preparation.Feed continuously 10 days, feed intake every day 2 times, experimental period 10 days, mortality rate and the cure rate of yellow sand Trionyx sinensis Wiegmann is calculated after terminating, computational methods: mortality rate=dead yellow sand Trionyx sinensis Wiegmann number/test yellow sand Trionyx sinensis Wiegmann number × 100%, cure rate=healing yellow sand Trionyx sinensis Wiegmann number/test yellow sand Trionyx sinensis Wiegmann number × 100%, the results are shown in following table.

	Number of elements	Mortality rate (%)	Cure rate (%)
				Matched group	90	35.56	45.56
Test group 1	90	4.44	95.56
				Test group 2	90	3.33	97.78
Test group 3	90	3.33	96.67
				Test group 4	90	4.44	95.56
Test group 5	90	3.33	96.67

As seen from the above table, test group and matched group contrast, mortality rate reduces 31.12%-32.23%, cure rate improves 50%-52.22%, illustrate that the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy of the present invention can strengthen immunity and the anti-stress ability of yellow sand Trionyx sinensis Wiegmann, reduce the mortality rate that yellow sand Trionyx sinensis Wiegmann suffers from drug induccd hepatopathy, improve cure rate.

Experiment four

Select 0.19-0.31kg, specification almost consistent and make a definite diagnosis the Margarita Trionyx sinensis Wiegmann 540 of drug induccd hepatopathy, be divided into three groups at random, i.e. matched group, test group 1, test group 2, test group 3, test group 4, test group 5, often group does 3 parallel laboratory tests, often organizes Margarita Trionyx sinensis Wiegmann 30.Matched group Margarita Trionyx sinensis Wiegmann is fed the basic feedstuff be mixed with Pomacea canaliculata powder, tapioca starch, Sal, dimethyl-β-DMPT, betanin, lysine, uridylate, holder Martin polypeptide, citronellal; The Margarita Trionyx sinensis Wiegmann of test group 1 is fed and is added with the basic feedstuff of the embodiment of the present invention 1 Chinese medicine preparation; The Margarita Trionyx sinensis Wiegmann of test group 2 is fed and is added with the basic feedstuff of the embodiment of the present invention 2 Chinese medicine preparation; The Margarita Trionyx sinensis Wiegmann of test group 3 is fed and is added with the basic feedstuff of the embodiment of the present invention 3 Chinese medicine preparation; The Margarita Trionyx sinensis Wiegmann of test group 4 is fed and is added with the basic feedstuff of the embodiment of the present invention 4 Chinese medicine preparation; The Margarita Trionyx sinensis Wiegmann of test group 5 is fed and is added with the basic feedstuff of the embodiment of the present invention 5 Chinese medicine preparation.Feed continuously 10 days, feed intake every day 2 times, experimental period 10 days, mortality rate and the cure rate of Margarita Trionyx sinensis Wiegmann is calculated after terminating, computational methods: mortality rate=dead Margarita Trionyx sinensis Wiegmann number/test Margarita Trionyx sinensis Wiegmann number × 100%, cure rate=healing Margarita Trionyx sinensis Wiegmann number/test Margarita Trionyx sinensis Wiegmann number × 100%, the results are shown in following table.

	Number of elements	Mortality rate (%)	Cure rate (%)
				Matched group	90	36.67	44.44
Test group 1	90	3.33	96.67
				Test group 2	90	3.33	97.78
Test group 3	90	4.44	96.67
				Test group 4	90	4.44	95.56
Test group 5	90	4.44	96.67

As seen from the above table, test group and matched group contrast, mortality rate reduces 32.23%-33.34%, cure rate improves 51.15%-53.34%, illustrate that the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy of the present invention can strengthen immunity and the anti-stress ability of Margarita Trionyx sinensis Wiegmann, reduce the mortality rate that Margarita Trionyx sinensis Wiegmann suffers from drug induccd hepatopathy, improve cure rate

Above content can not assert that the present invention specifically implements to be confined to these explanations; for the those of ordinary skill of technology neck belonging to the present invention; do not departing under concept thereof of the present invention; some simple deduction or replace can also be made, all should be considered as belonging to the scope of patent protection that the present invention is determined by submitted to claims.

Claims

1. treat the Chinese medicine preparation of testudinate drug induccd hepatopathy for one kind, it is characterized in that, in units of weight portion, comprise following raw material: Radix Bupleuri 20-30 part, Herba Visci 20-30 part, Fructus Lycii 20-30 part, Folium Artemisiae Argyi 20-30 part, Radix Polygoni Multiflori 20-30 part, Semen Plantaginis 12-20 part, Radix Stemonae 12-20 part, Herba Aristolochiae 12-20 part, Rhizoma Coptidis 12-20 part, Herba Patriniae 12-20 part, Radix Saposhnikoviae 8-16 part, Radix Puerariae 8-16 part, Herba Portulacae 8-16 part, Herba Menthae 8-16 part, Herba Siegesbeckiae 8-16 part, gold silver grass 6-12 part, Cortex Eucommiae 6-12 part, Bulbus Allii 6-12 part, Bulbus Lilii 6-12 part, Cortex Magnoliae Officinalis 6-12 part, Herba Houttuyniae 3-6 part, Herba Ranunculi Japonici 3-6 part, Radix Aconiti Kusnezoffii Preparata 3-6 part, Rhizoma Acori Graminei 3-6 part, Resina Ferulae 3-6 part.

2. the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy according to claim 1, it is characterized in that, in units of weight portion, comprise following raw material: Radix Bupleuri 22-28 part, Herba Visci 22-28 part, Fructus Lycii 22-28 part, Folium Artemisiae Argyi 22-28 part, Radix Polygoni Multiflori 22-28 part, Semen Plantaginis 14-18 part, Radix Stemonae 14-18 part, Herba Aristolochiae 14-18 part, Rhizoma Coptidis 14-18 part, Herba Patriniae 14-18 part, Radix Saposhnikoviae 10-14 part, Radix Puerariae 10-14 part, Herba Portulacae 10-14 part, Herba Menthae 10-14 part, Herba Siegesbeckiae 10-14 part, gold silver grass 8-10 part, Cortex Eucommiae 8-10 part, Bulbus Allii 8-10 part, Bulbus Lilii 8-10 part, Cortex Magnoliae Officinalis 8-10 part, Herba Houttuyniae 4-5 part, Herba Ranunculi Japonici 4-5 part, Radix Aconiti Kusnezoffii Preparata 4-5 part, Rhizoma Acori Graminei 4-5 part, Resina Ferulae 4-5 part.

3. the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy according to claim 2, it is characterized in that, in units of weight portion, comprise following raw material: Radix Bupleuri 25 parts, Herba Visci 25 parts, Fructus Lycii 25 parts, Folium Artemisiae Argyi 25 parts, Radix Polygoni Multiflori 25 parts, Semen Plantaginis 15 parts, the Radix Stemonae 15 parts, Herba Aristolochiae 15 parts, Rhizoma Coptidis 15 parts, Herba Patriniae 15 parts, Radix Saposhnikoviae 12 parts, Radix Puerariae 12 parts, Herba Portulacae 12 parts, Herba Menthae 12 parts, Herba Siegesbeckiae 12 parts, gold silver grass 8 parts, the Cortex Eucommiae 8 parts, 8 parts, Bulbus Allii, Bulbus Lilii 8 parts, Cortex Magnoliae Officinalis 8 parts, Herba Houttuyniae 5 parts, Herba Ranunculi Japonici 5 parts, Radix Aconiti Kusnezoffii Preparata 5 parts, Rhizoma Acori Graminei 5 parts, Resina Ferulae 5 parts.

4. a preparation method for the Chinese medicine preparation of the treatment testudinate drug induccd hepatopathy according to any one of claim 1-3, is characterized in that, comprise the following steps:

S2: by medical filtration obtained for step S1, concentrate, obtain mixture B;

5. the preparation method of the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy according to claim 4, is characterized in that, organic solvent described in step S1 comprise in ethanol, butanone, trichloroethane, Carbon bisulfide one or more.

6. the preparation method of the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy according to claim 4, it is characterized in that, the condition that the extraction method of ultrasonic assistant described in step S1 extracts medicinal liquid is: ultrasonic power is 150-170W, organic solvent concentration is 50%-80%, Extracting temperature is 50-70 DEG C, and extraction time is 30-50min.

7. the preparation method of the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy according to claim 4, it is characterized in that, step S2 herb liquid filters, and is concentrated into water content 10%-22%.

8. the preparation method of the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy according to claim 4, it is characterized in that, in step S3, mixture B is dried to water content 4%-6% at 95-105 DEG C.

9. the preparation method of the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy according to claim 4, it is characterized in that, the condition of sieving in step S3 is: cross 120-320 mesh sieve.

10. the preparation method of the Chinese medicine preparation for the treatment of testudinate drug induccd hepatopathy according to claim 4, it is characterized in that, the condition of sterilizing in step S3 is: temperature is 135-136 DEG C, and pressure is 220-230KPa, and the time is 1-2min.