CN105412736B - A kind of Chinese herbal medicine for oral administration and preparation method thereof for treating fibroadenoma of breast - Google Patents

A kind of Chinese herbal medicine for oral administration and preparation method thereof for treating fibroadenoma of breast Download PDF

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CN105412736B
CN105412736B CN201510901836.3A CN201510901836A CN105412736B CN 105412736 B CN105412736 B CN 105412736B CN 201510901836 A CN201510901836 A CN 201510901836A CN 105412736 B CN105412736 B CN 105412736B
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parts
pill
breast
radix
fibroadenoma
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CN105412736A (en
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张瓅方
丁生晨
刘彦丽
张景景
臧文华
郝鹏飞
周洁
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Nanyang Institute of Technology
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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Abstract

The invention discloses a kind of Chinese herbal medicines for oral administration and preparation method thereof for treating fibroadenoma of breast, are prepared from the following raw materials in parts by weight: 20~30 parts of Radix Astragali, 15~20 parts of Rhizoma Atractylodis Macrocephalae, 10~15 parts of Radix Angelicae Sinensis, 10~15 parts of Rhizoma Chuanxiong, 6~12 parts of stir-baked RADIX BUPLEURI with vinegar, 12~18 parts of radix paeoniae rubra, 8~13 parts of raw peach kernel, 10~15 parts of Fructus Aurantii, 5~10 parts of trigone, 5~10 parts of semen litchi, 5~10 parts of ramulus cinnamomi, 10~15 parts of Prunella vulgaris, 5~9 parts of Ramulus euonymi and 3~6 parts of Radix Glycyrrhizae.The present invention, which is directed to, causes the pathogenic factors of fibroadenoma of breast: such as ferritic virtual loss, Chong and Ren channel disorder, derangement of Qi and blood, feelings will is unsmooth, phlegm-blood stasis accumulation, overstrain internal injury or seven feelings are not relaxed, study the pathogenesis etiology and pathogenesis of the disease, using the organic conception and diagnosis and treatment of Chinese medicine macroscopic view, with reinvigoration, tonifying spleen is soothing the liver, the promoting flow of qi and blood circulation, reducing phlegm and resolving masses is main principle of reatment;Using tcm prescription " monarch, minister, help, make " the theory side of sending medication, reach eradication therapy purpose.

Description

A kind of Chinese herbal medicine for oral administration and preparation method thereof for treating fibroadenoma of breast
Technical field
The present invention relates to a kind of Chinese herbal medicines, more particularly, to a kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast and its system Preparation Method.
Background technique
Fibroadenoma of breast is that a kind of tumour of fibr tissue and galandular epithelium in lobule of mammary gland occurs, and is that breast is benign swollen One of the most common type in tumor, fibroadenoma of breast can betide postpubertal any women, but with 20~30 years old female in clinic Property to be most common, be occasionally found in menopausal woman.
Currently, doctor trained in Western medicine think to cause fibroadenoma of breast the cause of disease be mainly estrogen on breast tissue lasting stimulation and Breast tissue takes some drugs or virus infection, the mutation of autogene etc. to the high response of estrogen, and with patient. Doctor trained in Western medicine generallys use the method for operation to treat elimination fibroadenoma of breast, but brings the great negative heart to patient after operation It manages influence and huge financial burden and cannot achieve the effect that eradicate this disease, therefore can not received by many patients.
Chinese medicine is long-standing to fibroadenoma of breast treatment, and fibroadenoma of breast is referred to as newborn core within the scope of Chinese medicine, is Refer to the benign tumors that breast occurs.It is gained the name with wherein mammary nodule such as core ovum, belongs to " breast illness ", " newborn ruffian ", " tied in cream The scopes such as core ".Chinese medicine thinks that asthenia in origin and asthenia in superficiality, the congenital virtual loss of ferritic, Chong and Ren channel disorder are that generation fibroadenoma of breast is basic;Liver is lost Item reaches, phlegm and blood stasis caused by mechanism of qi pent-up is the product that fibroadenoma of breast occurs.In Publication No. CN102151325 B A kind of Chinese medicine for treating mammary gland disease of state's patent disclosure, by Radix Angelicae Sinensis, radix paeoniae rubra, raw peach kernel, safflower, Radix Salviae Miltiorrhizae, curcuma zedoary, corydalis tuber, river Rhizome of chuanxiong, pheretima, first pearl, Radix Rhapontici seu Radix Echinopsis, bulb of thunberg fritillary, spina gleditsiae, the seed of cowherb, the root of Dahurain angelica, radices trichosanthis, oyster, green peel, rhizoma cyperi, tangerine seed, radix bupleuri, Dandelion, edible tulip, Fructus Forsythiae, Radix Astragali, Radix Codonopsis, Radix Glycyrrhizae, olibanum, myrrh, Poria cocos and oldenlandia diffusa mixing composition;It can treat The diseases such as the proliferation of mammary gland, acute and chronic mastitis, adenofibroma of breast, breast illness.Application No. is the Chinese patents of CN104001112 A A kind of combined traditional Chinese medicine for treating fibroadenoma of breast of Shen Qing Publication, by following mass ratio Chinese medicinal composition: 10 parts of Radix Paeoniae Alba, Radix Curcumae 10 Part, 15 parts of chrysanthemum, 6 parts of green peel, 10 parts of kelp, 9 parts of radix achyranthis bidentatae, 10 parts of thizoma curculiginis, 10 parts of Herba Epimedii, 10 parts of the fleece-flower root, fructus lycii 10 Part, 10 parts of Cortex Phellodendri, 10 parts of Radix Salviae Miltiorrhizae, 10 parts of radix bupleuri, 10 parts of endothelium corneum gigeriae galli, 10 parts of the root bark of white mulberry.These Chinese materia medica preparation entirety prescriptions, therapy It is single, most table undertaking therapies from diseases such as Shugan Zhitong, resolving hard lumps, ignore it is basic " healthy tendency deposit in, heresy can not It is dry ", do not embody Chinese traditional treatment mammary gland disease dialectical the characteristics for the treatment of.
Summary of the invention
In view of this, in view of the deficiencies of the prior art, the present invention provides a kind of medium-height grass for oral administration for treating fibroadenoma of breast Medicine and preparation method thereof has achieved the effect that cure rate is high, recurrence rate is low, treating both manifestation and root cause of disease.
In order to achieve the above objectives, the invention adopts the following technical scheme:
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: Radix Astragali 20~30 Part, 15~20 parts of Rhizoma Atractylodis Macrocephalae, 10~15 parts of Radix Angelicae Sinensis, 10~15 parts of Rhizoma Chuanxiong, 6~12 parts of stir-baked RADIX BUPLEURI with vinegar, 12~18 parts of radix paeoniae rubra, raw peach kernel 8 ~13 parts, 10~15 parts of Fructus Aurantii, 5~10 parts of trigone, 5~10 parts of semen litchi, 5~10 parts of ramulus cinnamomi, 10~15 parts of Prunella vulgaris, terrible arrow 5~9 parts and 3~6 parts of Radix Glycyrrhizae of plumage.
Preferably, a kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: Radix Astragali 23~27 parts, 16~18 parts of Rhizoma Atractylodis Macrocephalae, 12~14 parts of Radix Angelicae Sinensis, 12~14 parts of Rhizoma Chuanxiong, 8~10 parts of stir-baked RADIX BUPLEURI with vinegar, 13~17 parts of radix paeoniae rubra, life 10~12 parts of peach kernel, 11~14 parts of Fructus Aurantii, 7~9 parts of trigone, 7~9 parts of semen litchi, 7~90 parts of ramulus cinnamomi, 11~14 parts of Prunella vulgaris, 6~8 parts and 4~5 parts of Radix Glycyrrhizae of Ramulus euonymi.
Preferably, a kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: Radix Astragali 25 parts, 17 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Chuanxiong, 9 parts of stir-baked RADIX BUPLEURI with vinegar, 15 parts of radix paeoniae rubra, 11 parts of raw peach kernel, 12 parts of Fructus Aurantii, trigone 8 Part, 8 parts of semen litchi, 7 parts of ramulus cinnamomi, 13 parts of Prunella vulgaris, 7 parts of Ramulus euonymi and 4 parts of Radix Glycyrrhizae.
Preferably, a kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, the stir-baked RADIX BUPLEURI with vinegar concocting method is: by northern bavin Removal impurity, residual stem, root recklessly, is cut into 3~4mm sheet, cleans, is dipped to and moisturizes, and takes out, dries, obtain Bupleurum Chinese piece;It presses It is Bupleurum Chinese piece: rice vinegar=4:1 ratio according to mass ratio, rice vinegar is added thereto and mixes thoroughly, bored profit to the rice vinegar is inhaled completely It receives, is put into mild fire fried dry in iron pan, sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up.
Present invention provides a kind of preparation methods of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, including following step It is rapid:
1) pretreatment of raw material: weighing the sieve that various medicinal raw materials smash it through 250~300 mesh according to formula rate, point Medicinal powder is not obtained;
2) it makes pill: the step 1) Chinese drugs powder, fecula, distilled water being modulated into bolus, by the medicine Group prepares molding pill with Chinese medicinal pills preparing machine;The molding pill is put into polishing case and is polished, the medicine after being polished Ball;Pill after the polishing is dried and gets product pill;
3) pack is handled: being collected finished product pill obtained in the step 2), is distributed into bag, every bag of 10g is then shut off Pellet processing machine, cleaning equipment.
Preferably, the preparation method of a kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, the bolus tune Process processed are as follows: take 50~100 parts of distilled water to be put into stainless-steel pan and be added 20~30 parts of fecula, mild fire, which is stirred continuously, is brewed into paste Shape pours into Stainless steel basin after molding.By medicinal powders various in the step 1), pours into the Stainless steel basin and stir Uniformly up to bolus.
Preferably, a kind of preparation method of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, which is characterized in that institute Pill drying process after the polishing stated are as follows: be uniformly placed in the pill after polishing in step 1) on pallet, by the support Disk is put into baking oven, and the pill water content ﹤ 10% after polishing is dried at 60~80 DEG C is to get finished product pill.
Pharmacological action of the invention is:
Radix Astragali, the sweet temperature of property is distributed in lung channel, has effects that tonifying Qi and lifting yang, invigorating qi for consolidating superficies.It is usually used in decoction or soaked generation tea Drink has good disease-prevention health effect.
Rhizoma Atractylodis Macrocephalae, bitter is sweet, warm-natured, returns spleen, stomach meridian.With strengthening the spleen and replenishing qi, the effect of eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.Often For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, threatened abortion.
Radix Angelicae Sinensis, property are sweet, pungent, warm.With enriching blood, invigorate blood circulation;The effect of menstruction regulating and pain relieving, moisturizing dryness and lubricating intestine.It is usually used in all diseases of the deficiency of blood, Amenorrhoea, dysmenorrhea;Asthenia cold abdominalgia, numbness, weight, ulcer sores after dysentery with bloody stool.
Rhizoma Chuanxiong, Rhizoma Chuanxiong are pungent, warm.With promote breath and open depression, the effect of method wind-dryness is wet, promoting blood circulation and stopping pain.It is usually used in irregular menstruation, Amenorrhea and algomenorrhea, lump in the abdomen abdominal pain, pricking pain in the chest, tumbling and swelling, headache, rheumatic arthralgia.
Radix bupleuri, property are bitter, pungent, slightly cold.With in soothing liver-qi stagnation effect and inducing diaphoresis, the effect of soothing the liver rising Yang.It is usually used in catching a cold Fever, fevers and chills alternate, malaria, liver depression and qi stagnation, chest and rib distending pain, rectal prolapse, uterine prolapse, irregular menstruation.
Radix paeoniae rubra, property are bitter, slightly cold.Return liver warp.With clearing heat and cooling blood, the effect of promoting blood circulation.It is usually used in febrile virulent maculae, spits blood Bleeding from five sense organs or subcutaneous tissue, red eye, swell pain, liver-depressed hypochondrium pain, amenorrhea and algomenorrhea, addiction lump in the abdomen abdominal pain, injury from falling down, carbuncle swells sore.
Raw peach kernel, property hardship, Gan Ping.With promoting blood circulation, relax bowel and defecation, relieving cough and asthma effect.It is usually used in amenorrhea and algomenorrhea, Lump in the abdomen lump in the abdomen lump in the abdomen, pulmonary abscess acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.
Fructus Aurantii, property hardship, pungent-warm.There is the effect of regulating the flow of QI to ease the stomach, row stagnant dissipate-swelling.It is usually used in the chest side of body stagnation of the circulation of vital energy, turgor pain, food Product is not changed, and stops in phlegm retention;Gastroptosis, rectal prolapse, sub-official prolapses.
Trigone, property are pungent, bitter.With breaking blood and promoting the circulation of qi, the effect of clearing stagnation and killing pain.It is usually used in abdominal mass lump in the abdomen, dysmenorrhea, hemostasis warp It closes, chest impediment and cardialgia, dyspepsia distending pain.
Semen litchi, property is pungent, slight bitter.With promoting the circulation of qi dissipating bind, the effect of cold-dispelling pain-relieving.It is usually used in cold hernia stomachache, testiclar gall.
Ramulus cinnamomi, acrid, sweet, warm.Return heart, lung, bladder meridian.With sweating expelling pathogenic factors from muscles and skin, warming meridian, help yang gas, flat and gas The effect of.It is usually used in anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, arthralgia, phlegm retention, oedema, palpitaition etc..
Prunella vulgaris, it is pungent, bitter, it trembles with fear.Return liver, gallbladder channel.With clearing heat-fire, the effect of improving eyesight, mass dissipating and swelling eliminating.
Ramulus euonymi, property are bitter, cold.With promoting circulation of blood promoting menstruation, the effect of removing blood stasis and acesodyne.It is usually used in menostasis, abdominal mass, postpartum stasis abdomen Bitterly, abdominal pain due to enterositosis, dermatitis rhus.
Radix Glycyrrhizae, property are sweet, flat.Have effects that tonifying middle-Jiao and Qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, mediation property of medicine. It is usually used in weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviation drug It is toxicity, strong.
Monarch drug in a prescription: Radix Astragali is sweet, tepor, air making-up and spleen enlivening, invigorating qi for consolidating superficies, rising Yang detoxification.Rhizoma Atractylodis Macrocephalae is sweet, bitter, tepor, and QI invigorating is strong Spleen, eliminate dampness and have diuretic effect.Radix Angelicae Sinensis is sweet, pungent, warm, tonifying blood and regulating menstruation, promoting blood circulation and stopping pain.Rhizoma Chuanxiong is pungent, warm, blood-activating and qi-promoting, wind-expelling pain-stopping.Vinegar Radix bupleuri is bitter, pungent, slightly cold, soothing liver-qi stagnation, lifting disease.Five medicines are that monarch plays building up healthful vital energy, tonifying Qi and blood altogether, raises to rush and appoint it Function.Ministerial drug: radix paeoniae rubra hardship, slightly cold, clearing liver-fire, removing blood stasis and acesodyne.Raw peach kernel hardship, Gan Ping, promoting blood circulation.Fructus Aurantii property is bitter, pungent Temperature, relieving stagnant Qi disperse accumulation, eliminating phlegm and dispersing mass.Trigone is pungent, bitter, breaking blood and promoting the circulation of qi, clearing stagnation and killing pain.Lichee nuclearity is pungent, slight bitter, qi-regulating dissipating bind, It is warming channel and expelling cold.Five medicines are that minister plays promoting qi circulation and relieving pain, promoting blood circulation altogether, and dissipating bind disappears the function of ruffian.Supplementary drug: ramulus cinnamomi is pungent, Gan Wen, supporing yang Change gas, warming meridian.Prunella vulgaris property bitter, acrid, cold, clearing liver nourishing the liver, mass dissipating and swelling eliminating.Ramulus euonymi hardship, cold, promoting circulation of blood promoting menstruation, dissipate the stasis of blood Analgesic.Three medicines are assistant, assist monarch, minister temperature through nourishing the liver, blood-activating analgetic.Make medicine: Radix Glycyrrhizae property is sweet, flat, invigorate the spleen and benefit qi, relieving spasm to stop pain, Coordinating the drug actions of a prescription.
The beneficial effects of the present invention are:
The present invention is directed to the pathogenic factors for causing fibroadenoma of breast: such as ferritic virtual loss, Chong and Ren channel disorder, derangement of Qi and blood, feelings Will is unsmooth, phlegm-blood stasis is gathered, and overstrain internal injury or seven feelings are not relaxed, and studies the pathogenesis etiology and pathogenesis of the disease, using Chinese medicine macroscopic view Organic conception and diagnosis and treatment, with reinvigoration, tonifying spleen is soothing the liver, the promoting flow of qi and blood circulation, reducing phlegm and resolving masses be main principle of reatment;Using Tcm prescription " monarch minister, helps, makes " the theory side of sending medication, reaches eradication therapy purpose.Specifically there is the following:
(1) radix bupleuri is the dry root of umbelliferae bupleurum or radix bupleuri scorzoneraefolii, acrid flavour, hardship, and cold nature returns liver, gallbladder, lung Through and inducing diaphoresis in, soothing liver-qi stagnation, yang invigorating, bring down a fever cut it is cruel.But single radix bupleuri effect is not significant, is not able to satisfy at present Demand.The present invention uses stir-baked RADIX BUPLEURI with vinegar, on the one hand, radix bupleuri enters liver and gallbladder warp, and by soaking in rice vinegar, stir-baked RADIX BUPLEURI with vinegar master enters Liver Channel, can be with Mitigate the scattered property of the liter of itself, the effect of soothing liver-qi stagnation and blood and relieving pain significantly increases;On the other hand, bavin in the stir-baked RADIX BUPLEURI with vinegar after vinegar toast Hu saponin component increased significantly, and have preferable anti-inflammatory and increase immunity function.Therefore, after the present invention selects stir-baked RADIX BUPLEURI with vinegar to crush It is used as medicine, the effect of soothing liver-qi stagnation and blood and relieving pain and improves the effect of sufferer immunity of organisms and significantly increase.
(2) peach kernel is the dry mature seed of rosaceous plant peach, is harvested after fruit maturation, removes pulp and nucleocapsid, takes Seed out dries.Li Shizhen (1518-1593 A.D.) points out that " main stasis, wandering arthritis, hectic fever due to yin, liver malaria, fever and chills, promoting circulation of blood preferably connect peach kernel in " wood grass detailed outline " Skin point is raw to be used ";Su Song is also explicitly pointed out in " figure is through the wooden grass ", and peach kernel, which is used as medicine, to be " good " with this survivor;In modern study It confirms, the effect of raw peach kernel promoting blood circulation is most strong, fries, acts on obvious mitigate after steaming;Last peach kernel skin also have apparent promoting blood circulation, Anti-inflammatory effect, the peach kernel skin after stir-fry are easy to fall off and are denaturalized, therefore peach kernel is used as medicine and is advisable with raw with smashing.Raw peach is selected in the present invention Benevolence is used as medicine after directly crushing, and promoting blood circulation effect in general medicament than using peach kernel more obvious.
(3) a kind of Chinese herbal medicine for treating fibroadenoma of breast of the invention, compatibility is proper, and there is reinvigoration, tonifying spleen to dredge Liver, the promoting flow of qi and blood circulation, reducing phlegm and resolving masses and other effects, the treatment suitable for fibroadenoma of breast.With cure rate is high, recurrence rate is low, mark Originally simultaneous to control;The raw material of all selections of Chinese herbal medicine of the invention simultaneously is nontoxic pure natural Chinese herbal medicine, therefore is not had any Toxic side effect takes safety.
(4) a kind of Chinese herbal medicine for treating fibroadenoma of breast of the invention, through crushing production finished product pill, preparation Process simplicity, mild condition, easily controllable, the cost of raw material of use is cheap, is suitable for producing in enormous quantities.
Specific embodiment
The present invention will be further described below with reference to examples.
Embodiment 1
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: 20 parts of Radix Astragali, white 20 parts of art, 10 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 6 parts of stir-baked RADIX BUPLEURI with vinegar, 18 parts of radix paeoniae rubra, 8 parts of raw peach kernel, 10 parts of Fructus Aurantii, 5 parts of trigone, semen litchi 10 parts, 5 parts of ramulus cinnamomi, 15 parts of Prunella vulgaris, 9 parts of Ramulus euonymi and 6 parts of Radix Glycyrrhizae.
Preparation method includes the following steps:
1) pretreatment of raw material: removing impurity, residual stem, root for Bupleurum Chinese, be cut into 3mm sheet, clean, be dipped to and moisturize, It is dried after taking-up, obtains Bupleurum Chinese piece;It is Bupleurum Chinese piece: rice vinegar=4:1 ratio according to mass ratio, rice vinegar is added thereto and mixes Even, bored profit is completely absorbed to rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up;Then according to formula Ratio weighs the sieve that various medicinal raw materials smash it through 250 mesh, respectively obtains medicinal powder;
2) it makes pill: taking 80 parts of distilled water to be put into stainless-steel pan and be added 24 parts of fecula, mild fire, which is stirred continuously, to be brewed into Paste pours into Stainless steel basin after molding.Medicinal powders various in step 1) are poured into Stainless steel basin and are stirred evenly up to medicine Group;Bolus is prepared into molding pill with Chinese medicinal pills preparing machine;Molding pill is put into after being polished in polishing case, after being polished Pill;Pill after polishing is uniformly placed on pallet, pallet is put into baking oven, pill water content 8% is dried at 60 DEG C, Get product pill;
3) pack is handled: collection step 2) in finished product pill obtained be distributed into bag, every bag of 10g is then shut off pellet processing machine, Cleaning equipment.
Embodiment 2
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: 30 parts of Radix Astragali, white 15 parts of art, 15 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 12 parts of stir-baked RADIX BUPLEURI with vinegar, 12 parts of radix paeoniae rubra, 13 parts of raw peach kernel, 15 parts of Fructus Aurantii, 10 parts of trigone, litchi 5 parts of core of branch, 10 parts of ramulus cinnamomi, 10 parts of Prunella vulgaris, 5 parts of Ramulus euonymi and 3 parts of Radix Glycyrrhizae.
Preparation method includes the following steps:
1) pretreatment of raw material: first removing impurity, residual stem, root for Bupleurum Chinese, be cut into 4mm sheet, cleans, is dipped to profit Thoroughly, it is dried after taking-up, obtains Bupleurum Chinese piece;Be Bupleurum Chinese piece according to mass ratio: rice vinegar is added in rice vinegar=4:1 ratio thereto It mixes thoroughly, bored profit is completely absorbed to rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up;Then according to matching Square ratio weighs the sieve that various medicinal raw materials smash it through 300 mesh, respectively obtains medicinal powder;
2) it makes pill: taking 90 parts of distilled water to be put into stainless-steel pan and be added 26 parts of fecula, mild fire, which is stirred continuously, to be brewed into Paste pours into Stainless steel basin after molding.Medicinal powders various in step 1) are poured into Stainless steel basin and are stirred evenly up to medicine Group;Bolus is prepared into molding pill with Chinese medicinal pills preparing machine;Molding pill is put into after being polished in polishing case, after being polished Pill;Pill after polishing is uniformly placed on pallet, pallet is put into baking oven, pill water content 7% is dried at 70 DEG C, Get product pill;
3) pack is handled: collection step 2) in finished product pill obtained be distributed into bag, every bag of 10g is then shut off pellet processing machine, Cleaning equipment.
Embodiment 3
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: 25 parts of Radix Astragali, white 18 parts of art, 12 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 8 parts of stir-baked RADIX BUPLEURI with vinegar, 16 parts of radix paeoniae rubra, 10 parts of raw peach kernel, 12 parts of Fructus Aurantii, 9 parts of trigone, lichee 7 parts of core, 8 parts of ramulus cinnamomi, 12 parts of Prunella vulgaris, 7 parts of Ramulus euonymi and 4 parts of Radix Glycyrrhizae.
Preparation method includes the following steps:
1) pretreatment of raw material: first removing impurity, residual stem, root for Bupleurum Chinese, be cut into 3mm sheet, cleans, is dipped to profit Thoroughly, it is dried after taking-up, obtains Bupleurum Chinese piece;Be Bupleurum Chinese piece according to mass ratio: rice vinegar is added in rice vinegar=4:1 ratio thereto It mixes thoroughly, bored profit is completely absorbed to rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up;Then according to matching Square ratio weighs the sieve that various medicinal raw materials smash it through 270 mesh, respectively obtains medicinal powder;
2) it makes pill: taking 70 parts of distilled water to be put into stainless-steel pan and be added 22 parts of fecula, mild fire, which is stirred continuously, to be brewed into Paste pours into Stainless steel basin after molding.Medicinal powders various in step 1) are poured into Stainless steel basin and are stirred evenly up to medicine Group;Bolus is prepared into molding pill with Chinese medicinal pills preparing machine;Molding pill is put into after being polished in polishing case, after being polished Pill;Pill after polishing is uniformly placed on pallet, pallet is put into baking oven, pill water content 6% is dried at 80 DEG C, Get product pill;
3) pack is handled: collection step 2) in finished product pill obtained be distributed into bag, every bag of 10g is then shut off pellet processing machine, Cleaning equipment.
Embodiment 4
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: 27 parts of Radix Astragali, white 16 parts of art, 14 parts of Radix Angelicae Sinensis, 11 parts of Rhizoma Chuanxiong, 10 parts of stir-baked RADIX BUPLEURI with vinegar, 15 parts of radix paeoniae rubra, 11 parts of raw peach kernel, 13 parts of Fructus Aurantii, 6 parts of trigone, lichee 9 parts of core, 7 parts of ramulus cinnamomi, 11 parts of Prunella vulgaris, 8 parts of Ramulus euonymi and 5 parts of Radix Glycyrrhizae.
Preparation method includes the following steps:
1) pretreatment of raw material: first removing impurity, residual stem, root for Bupleurum Chinese, be cut into 4mm sheet, cleans, is dipped to profit Thoroughly, it is dried after taking-up, obtains Bupleurum Chinese piece;Be Bupleurum Chinese piece according to mass ratio: rice vinegar is added in rice vinegar=4:1 ratio thereto It mixes thoroughly, bored profit is completely absorbed to rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up;Then according to matching Square ratio weighs the sieve that various medicinal raw materials smash it through 280 mesh, respectively obtains medicinal powder;
2) it makes pill: taking 60 parts of distilled water to be put into stainless-steel pan and be added 20 parts of fecula, mild fire, which is stirred continuously, to be brewed into Paste pours into Stainless steel basin after molding.Medicinal powders various in step 1) are poured into Stainless steel basin and are stirred evenly up to medicine Group;Bolus is prepared into molding pill with Chinese medicinal pills preparing machine;Molding pill is put into after being polished in polishing case, after being polished Pill;Pill after polishing is uniformly placed on pallet, pallet is put into baking oven, pill water content 5% is dried at 70 DEG C, Get product pill;
3) pack is handled: collection step 2) in finished product pill obtained be distributed into bag, every bag of 10g is then shut off pellet processing machine, Cleaning equipment.
Embodiment 5
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: 22 parts of Radix Astragali, white 19 parts of art, 11 parts of Radix Angelicae Sinensis, 12 parts of Rhizoma Chuanxiong, 7 parts of stir-baked RADIX BUPLEURI with vinegar, 17 parts of radix paeoniae rubra, 12 parts of raw peach kernel, 11 parts of Fructus Aurantii, 7 parts of trigone, lichee 8 parts of core, 6 parts of ramulus cinnamomi, 14 parts of Prunella vulgaris, 6 parts of Ramulus euonymi and 3 parts of Radix Glycyrrhizae.
Preparation method includes the following steps:
1) pretreatment of raw material: first removing impurity, residual stem, root for Bupleurum Chinese, be cut into 3mm sheet, cleans, is dipped to profit Thoroughly, it is dried after taking-up, obtains Bupleurum Chinese piece;Be Bupleurum Chinese piece according to mass ratio: rice vinegar is added in rice vinegar=4:1 ratio thereto It mixes thoroughly, bored profit is completely absorbed to rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up;Then according to matching Square ratio weighs the sieve that various medicinal raw materials smash it through 260 mesh, respectively obtains medicinal powder;
2) it makes pill: taking 60 parts of distilled water to be put into stainless-steel pan and be added 20 parts of fecula, mild fire, which is stirred continuously, to be brewed into Paste pours into Stainless steel basin after molding.Medicinal powders various in step 1) are poured into Stainless steel basin and are stirred evenly up to medicine Group;Bolus is prepared into molding pill with Chinese medicinal pills preparing machine;Molding pill is put into after being polished in polishing case, after being polished Pill;Pill after polishing is uniformly placed on pallet, pallet is put into baking oven, pill water content 7% is dried at 80 DEG C, Get product pill;
3) pack is handled: collection step 2) in finished product pill obtained be distributed into bag, every bag of 10g is then shut off pellet processing machine, Cleaning equipment.
Embodiment 6
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: 28 parts of Radix Astragali, white 17 parts of art, 13 parts of Radix Angelicae Sinensis, 14 parts of Rhizoma Chuanxiong, 9 parts of stir-baked RADIX BUPLEURI with vinegar, 14 parts of radix paeoniae rubra, 9 parts of raw peach kernel, 14 parts of Fructus Aurantii, 8 parts of trigone, semen litchi 6 parts, 9 parts of ramulus cinnamomi, 13 parts of Prunella vulgaris, 9 parts of Ramulus euonymi and 6 parts of Radix Glycyrrhizae.
Preparation method includes the following steps:
1) pretreatment of raw material: first removing impurity, residual stem, root for Bupleurum Chinese, be cut into 4mm sheet, cleans, is dipped to profit Thoroughly, it is dried after taking-up, obtains Bupleurum Chinese piece;Be Bupleurum Chinese piece according to mass ratio: rice vinegar is added in rice vinegar=4:1 ratio thereto It mixes thoroughly, bored profit is completely absorbed to rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up;Then according to matching Square ratio weighs the sieve that various medicinal raw materials smash it through 290 mesh, respectively obtains medicinal powder;
2) it makes pill: taking 90 parts of distilled water to be put into stainless-steel pan and be added 30 parts of fecula, mild fire, which is stirred continuously, to be brewed into Paste pours into Stainless steel basin after molding.Medicinal powders various in step 1) are poured into Stainless steel basin and are stirred evenly up to medicine Group;Bolus is prepared into molding pill with Chinese medicinal pills preparing machine;Molding pill is put into after being polished in polishing case, after being polished Pill;Pill after polishing is uniformly placed on pallet, pallet is put into baking oven, pill water content 8% is dried at 70 DEG C, Get product pill;
3) pack is handled: collection step 2) in finished product pill obtained be distributed into bag, every bag of 10g is then shut off pellet processing machine, Cleaning equipment.
Embodiment 7
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: 29 parts of Radix Astragali, white 16 parts of art, 10 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Chuanxiong, 11 parts of stir-baked RADIX BUPLEURI with vinegar, 13 parts of radix paeoniae rubra, 13 parts of raw peach kernel, 10 parts of Fructus Aurantii, 9 parts of trigone, lichee 6 parts of core, 7 parts of ramulus cinnamomi, 15 parts of Prunella vulgaris, 5 parts of Ramulus euonymi and 4 parts of Radix Glycyrrhizae.
Preparation method includes the following steps:
1) pretreatment of raw material: first removing impurity, residual stem, root for Bupleurum Chinese, be cut into 4mm sheet, cleans, is dipped to profit Thoroughly, it is dried after taking-up, obtains Bupleurum Chinese piece;Be Bupleurum Chinese piece according to mass ratio: rice vinegar is added in rice vinegar=4:1 ratio thereto It mixes thoroughly, bored profit is completely absorbed to rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up;Then according to matching Square ratio weighs the sieve that various medicinal raw materials smash it through 300 mesh, respectively obtains medicinal powder;
2) it makes pill: taking 80 parts of distilled water to be put into stainless-steel pan and be added 24 parts of fecula, mild fire, which is stirred continuously, to be brewed into Paste pours into Stainless steel basin after molding.Medicinal powders various in step 1) are poured into Stainless steel basin and are stirred evenly up to medicine Group;Bolus is prepared into molding pill with Chinese medicinal pills preparing machine;Molding pill is put into after being polished in polishing case, after being polished Pill;Pill after polishing is uniformly placed on pallet, pallet is put into baking oven, pill water content 6% is dried at 60 DEG C, Get product pill;
3) pack is handled: collection step 2) in finished product pill obtained be distributed into bag, every bag of 10g is then shut off pellet processing machine, Cleaning equipment.
Embodiment 8
A kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, is prepared from the following raw materials in parts by weight: 24 parts of Radix Astragali, white 17 parts of art, 15 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 6 parts of stir-baked RADIX BUPLEURI with vinegar, 16 parts of radix paeoniae rubra, 8 parts of raw peach kernel, 15 parts of Fructus Aurantii, 10 parts of trigone, lichee 5 parts of core, 10 parts of ramulus cinnamomi, 12 parts of Prunella vulgaris, 8 parts of Ramulus euonymi and 5 parts of Radix Glycyrrhizae.
Preparation method includes the following steps:
1) pretreatment of raw material: first removing impurity, residual stem, root for Bupleurum Chinese, be cut into 3mm sheet, cleans, is dipped to profit Thoroughly, it is dried after taking-up, obtains Bupleurum Chinese piece;Be Bupleurum Chinese piece according to mass ratio: rice vinegar is added in rice vinegar=4:1 ratio thereto It mixes thoroughly, bored profit is completely absorbed to rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains stir-baked RADIX BUPLEURI with vinegar after taking-up;Then according to matching Square ratio weighs the sieve that various medicinal raw materials smash it through 250 mesh, respectively obtains medicinal powder;
2) it makes pill: taking 50 parts of distilled water to be put into stainless-steel pan and be added 20 parts of fecula, mild fire, which is stirred continuously, to be brewed into Paste pours into Stainless steel basin after molding.Medicinal powders various in step 1) are poured into Stainless steel basin and are stirred evenly up to medicine Group;Bolus is prepared into molding pill with Chinese medicinal pills preparing machine;Molding pill is put into after being polished in polishing case, after being polished Pill;Pill after polishing is uniformly placed on pallet, pallet is put into baking oven, pill water content 4% is dried at 60 DEG C, Get product pill;
3) pack is handled: collection step 2) in finished product pill obtained be distributed into bag, every bag of 10g is then shut off pellet processing machine, Cleaning equipment
Clinical test
One, general information
From in April, 2012 in April, 2015, fibroadenoma of breast female patient 217 are treated, the age was at 16-55 years old Between.
Two, diagnostic criteria
Fibroadenoma of breast diagnostic criteria: (1) lump in breast (with or without feeling of pain), surface is smooth, mobility is good, Quality is medium.(2) x-ray shows as round or similar round mass, and clear border, nothing is fuzzy, density is medium.(3) physical examination breast table Face and surrounding skin without it is abnormal change, nipple without invagination and discharge, armpit and clavicle area lymph node without enlargement.
Three, efficacy assessment standard
It is evaluated, is divided into according to the Standards for Diagnosis and Curative Effect of Chinese Medical Symptom that State Administration of Traditional Chinese Medicine formulates:
(1) cure: lump in breast and feeling of pain disappear, and are discontinued 3 months and do not recur.
(2) effective: lump in breast diameter reduces > 1/2, and feeling of pain disappears.
(3) effectively: lump in breast diameter reduces<1/2, and feeling of pain mitigates or lump in breast reduces>1/2, and feeling of pain does not subtract Gently.
(4) invalid: lump in breast do not reduce or increase instead be hardened or simple pain relief and lump does not reduce.
Four, therapeutic scheme
The Chinese herbal medicine is applicable in the treatment each card type of fibroadenoma of breast, in therapeutic process, the random embodiment of the present invention 1 of patient Finished product pill made from~8, specific instructions of taking be with warm water delivery service, once a bag, 3 times a day, take within 1 hour after meal;Clothes Prohibit pungent greasy, cold and cool food during medicine.2 Mondays are the course for the treatment of, clinical symptoms lighter patient's medication 2 courses for the treatment of, serious patients It takes medicine 4 courses for the treatment of.
Five, statistical result
136 cases got cured, effective 42, effective 27, invalid 12, total effective rate 94.47%.
Typical case
Case 1: Zhao, female, 21 years old, student, Nanyang, henan people.Readme close on university practice distribution, self-induction pressure compared with Greatly, it is easy mood swing.In April, 2012, Zhao have been surprisingly found that there is a cystic mass in left breast outside upper quadrant when taking a shower, Size as about semen viciae fabae is checked oneself, without pain, mobility are good, without other abnormal changes and sense of discomfort, come here then and go to a doctor, through physical examination It is diagnosed as fibroadenoma of breast with x-ray auxiliary examination, after taking 2 courses for the treatment of of drug of the present invention, no clinical symptoms, x-ray checks gland Tumor disappears.Effect of follow-up visit by telephone does not recur after half a year.
Case 2: it is pungent certain, female, 19 years old, student, Henan people from Sheqi County.The student selects again after mother patient describes college entrance examination failure It is secondary re-reading, usually learn rhythm anxiety, silencing has few desires and is reluctant to exchange with people.Winter in 2013, oneself is newborn on the left of discovery when having a bath There is a soya bean size foreign matter in room outside upper quadrant, it is painless, it is reluctant to refer to this thing with anyone for fear of privacy.This is swollen after half a year Block is gradually increased, and as indistinct sense of discomfort occurs in the menstrual cycle, comes to go to a doctor in July, 2013 after telling household then.Through me Place, which checks, is diagnosed as fibroadenoma of breast, and after taking 2.5 courses for the treatment of of drug of the present invention, sense of discomfort disappears, x-ray checks that adenoma also disappears It loses.Effect of follow-up visit by telephone does not recur after half a year.
Case 3: Sun, female, 36 years old, worker, people from Henan Fangcheng.Patient readme accidentally laid one's hand on before January and breast on the right side of it is outside upper And have lump at two in outer quadrant, check local hospital is medical, two newborn block quality are medium, clear border, and mobility is good, pushes away It is removable, have feeling of pain with the menstrual cycle, size is respectively 0.3 × 0.5cm, 0.5 × 0.8cm, is diagnosed as mammary gland fiber gland Tumor.It is consciously not improved after taking the drugs such as Ru Pi Ling", in March, 2014, carrys out here treatment then.Take drug 3 of the present invention After the course for the treatment of, it is painless, through x-ray check lump also disappear.Effect of follow-up visit by telephone does not recur after half a year.
Case 4: gold certain, female, 25 years old, worker, Nanyang, henan people.Patient's readme is since working, and work pressure on ordinary days Power is big, often stays up late for work, menstruation irregularis.Have been surprisingly found that in right breast outer quadrant there is a lump about when having a bath before one week For semen viciae fabae size, come here then and go to a doctor in October, 2014, through physical examination discovery lump is smooth, mobility is good, clear border, quality Medium no tubercle sense.X-ray shows right breast outer quadrant lump clear border, without fuzzy, density is medium.It is diagnosed as mammary gland fibre Tie up adenoma.After taking 2 courses for the treatment of of drug of the present invention, sense of discomfort disappears, x-ray checks that adenoma also disappears.Effect of follow-up visit by telephone is not after half a year Once it recurred.
Case 5: Mr. Wang, female, 42 years old, civil servant, Nanyang, henan people.In employee's Physical Check-Ups before patient's readme three days It was found that left breast outer quadrant has 1 × 1.3 cm Silent Neuritis lump, mammary gland fiber gland is diagnosed as after the inspection such as x-ray Tumor.Start in November, 2013 after taking 2.5 courses for the treatment of of drug of the present invention, further consultation x-ray etc. checks that lump disappears again.It is electric after half a year Words follow-up was not recurred.
Case 6: week certain, female, 52 years old, cadre.Patient's readme is because personality is irritable on ordinary days greatly for operating pressure.Five years ago has been found The proliferation of mammary gland, oneself takes always the drug therapies such as Ru Pi Ling", and clinical symptoms are good or bad.It was found in unit physical examination before 1 year Right breast outside upper quadrant has small mammary gland fibroma at 1, does not take notice of.It is again newborn at same district domain discovery 2 when further consultation after half a year Gland adenofibroma, although mobility is good, it is no other performance with it is excited when tingling sensation it is obvious.Because being suffered from before its mother 3 years Breast cancer is dead, oneself heart extremely worries frightened canceration, and it is medical to come here then in August, 2014.Take drug 4 of the present invention After the course for the treatment of, patient mood is stablized, and feels the tingling sensation disappearance of breast, x-ray checks that adenoma also disappears.Effect of follow-up visit by telephone after half a year It did not recurred.
Case 7: Xiao, female, 28 years old, teacher, Henan people from Zhoukou City.Discovery has left side when marriage physical examination before patient's readme half a year Breast inner lower quadrant has fibroadenoma of breast at 1, because without any abnormal feeling, not taking any drug on ordinary days, also not weighing Depending on this thing.The child of man and wife's family planning after marriage, worrying this disease to have an impact to lactation etc., to come here medical by spy.On inspection: adenoma Body is smooth, mobility is good, without any adhesion, pressing herein with tingling sensation, B ultrasound reality left breast inner lower quadrant adenoma is about For 1.2 × 1.5cm, x-ray showing edge understands without fuzzy, density is medium.Because patient's fearness influence is beautiful, is reluctant operative treatment, Start in January, 2015 to check after taking 2.5 courses for the treatment of of drug of the present invention, adenoma disappears, without any discomfort sense.After half a year phone with Visit was not recurred.
Case 8: Mr. Wang, female, 24 years old, student, Henan Tanghe people.It quarrels before patient's readme three months with boyfriend, mood is low It falls, feels that right breast distending pain always, menstruation the last week pain are obvious then.It is checked in Hospital, B ultrasound is shown: right newborn 3 o'clock is close There is 2.6 × 1.7cm lump at mammary areola, clear-cut margin has no obvious calcification, and bilateral axillary regions and clavicle area are shown no obvious abnormalities Lymph node is diagnosed as fibroadenoma of breast.The drugs such as Xiaojin Dan are taken, effect is unobvious, in January, 2015, carrys out here treatment then. After taking 3 courses for the treatment of of drug of the present invention, the disappearance of check lump, the clinical symptoms without any discomfort.Effect of follow-up visit by telephone be not after half a year Recurrence.
Case 9: Lee, female, 22 years old, student, Henan people from Zhenping.Patient's two years ago right breast suffers from fibroadenoma of breast, In Local county people's hospital is treated using surgical removal.Nearly half a year, there are also lump senses for self-examination panesthesia operative site, then It is medical to come here.Through physical examination, lump mobility is good, without adhesion, presses slight shouting pain, size is about 1.0 × 1.3cm, and x-ray is shown Form rule, clear border, quality are medium.It is diagnosed as fibroadenoma of breast again, patient is reluctant to perform the operation again, in August, 2014 Start voluntarily to receive drug therapy of the present invention, the disappearance of check lump, the clinical symptoms without any discomfort after 3 courses for the treatment of.After half a year Effect of follow-up visit by telephone did not recurred.
Case 10: Xu certain, female, 30 years old, secretary, Nanyang, henan people.Patient serves as certain real estate project Executive Secretary, throughout the year Other places is gone on business with leader, feels spiritual high-pressure, chronic insomnia, menstruation irregularis.The left inside side of breast was found before 2 months Quadrant has 1 small lump of capsule, does not take notice of this thing then because working outside without pain by touching.Subsequent every pressure that is busy with one's work is big When, there is tingling sensation in this lump, and it is medical to come here in May, 2013.There is capsule at the nearly mammary areola of the physical examination discovery left inner side quadrant of breast Knurl, what is pushed away is removable, movable good, with surrounding tissue without adhesion, mild tenderness.Surrounding skin and lymph node region are without exception.X Line shows that lump clear border, quality are medium.It is diagnosed as fibroadenoma of breast.Drug therapy of the present invention is taken, is answered after 3 courses for the treatment of Look into that lump disappears, the clinical symptoms without any discomfort, is emotionally stable, sleeping also is greatly improved.Effect of follow-up visit by telephone after half a year It did not recurred.
Finally, it is stated that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, this field is common Other modifications or equivalent replacement that technical staff makes technical solution of the present invention, without departing from technical solution of the present invention Spirit and scope, be intended to be within the scope of the claims of the invention.

Claims (1)

1. a kind of Chinese herbal medicine for oral administration for treating fibroadenoma of breast, which is characterized in that be prepared from the following raw materials in parts by weight: yellow 25 parts of stilbene, 17 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of Radix Angelicae Sinensis, 13 parts of Rhizoma Chuanxiong, 9 parts of stir-baked RADIX BUPLEURI with vinegar, 15 parts of radix paeoniae rubra, 11 parts of raw peach kernel, 12 parts of Fructus Aurantii, trigone 8 parts, 8 parts of semen litchi, 7 parts of ramulus cinnamomi, 13 parts of Prunella vulgaris, 7 parts of Ramulus euonymi and 4 parts of Radix Glycyrrhizae;
The stir-baked RADIX BUPLEURI with vinegar concocting method is: Bupleurum Chinese removed into impurity, residual stem, root, is cut into 3~4mm sheet, is cleaned, leaching Bubble takes out to moisturizing, dries, obtain Bupleurum Chinese piece;According to mass ratio be Bupleurum Chinese piece: rice vinegar=4:1 ratio, thereto plus Enter rice vinegar to mix thoroughly, bored profit is completely absorbed to the rice vinegar, is put into mild fire fried dry in iron pan, and sunning obtains vinegar bavin after taking-up Recklessly;
The preparation method of the Chinese herbal medicine for oral administration of the treatment fibroadenoma of breast, comprising the following steps:
1) pretreatment of raw material: weighing the sieve that various medicinal raw materials smash it through 250~300 mesh according to formula rate, respectively To medicinal powder;
2) it makes pill: the step 1) Chinese drugs powder, fecula, distilled water being modulated into bolus, then by the medicine Group prepares molding pill with Chinese medicinal pills preparing machine;The molding pill is put into after being polished in polishing case, after being polished Pill;Pill after the polishing is dried and gets product pill;
3) pack is handled: being collected finished product pill obtained in the step 2), is distributed into bag, every bag of 10g is then shut off pill Machine, cleaning equipment;
The bolus modulated process are as follows: it takes 50~100 parts of distilled water to be put into stainless-steel pan and is added 20~30 parts of fecula, mild fire It is stirred continuously and is brewed into paste, poured into Stainless steel basin after molding, medicinal powders various in the step 1) pour into described Stainless steel basin in stir evenly up to bolus;
Pill drying process after the polishing are as follows: be uniformly placed in the pill after polishing in step 2 on pallet, by institute The pallet stated is put into baking oven, and the pill water content ﹤ 10% after the polishing is dried at 60~80 DEG C is to get finished medicines Ball.
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Title
活血化瘀法治疗乳房纤维腺瘤12例疗效观察;贾金梅;《北京中医杂志》;20020228;第21卷(第1期);第62-63页,尤其是第62页摘要 *

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