CN105412205A - Medicine for treating ascites due to cirrhosis - Google Patents

Medicine for treating ascites due to cirrhosis Download PDF

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Publication number
CN105412205A
CN105412205A CN201510950424.9A CN201510950424A CN105412205A CN 105412205 A CN105412205 A CN 105412205A CN 201510950424 A CN201510950424 A CN 201510950424A CN 105412205 A CN105412205 A CN 105412205A
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parts
medicine
cirrhosis
ascites
root bark
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吴福
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/10Bryophyta (mosses)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

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Abstract

The invention discloses a medicine for treating ascites due to cirrhosis, relates to a medicine and provides the medicine for treating ascites due to cirrhosis. The medicine is characterized by being prepared from the following traditional Chinese medicines in parts by weight: 6-30 parts of cornu bubali, 3-12 parts of black morning glory seed, 3-12 parts of white morning glory seed, 6-30 parts of Chinese aralis root bark, 6-30 parts of sapium japonicum root bark, 6-20 parts of calabash shell, 6-30 parts of herba portulacae and 6-30 parts of Stem and leaf of Hongkong Pavetta. According to the medicine, the medicines are combined and act together for exerting the functions of improving blood flow of liver and portal system, reducing portal hypertension, resisting angiotensin, increasing renal blood flow to promote urination, relax the bowels and remove toxins, improving liver function and accelerating protein synthesis, so that the purpose of quickly eliminating ascites is achieved; the clinical practice proves that the medicine for treating ascites due to cirrhosis is significant in curative effect.

Description

A kind of medicine for the treatment of cirrhotic ascites
Technical field
The present invention relates to a kind of medicine, especially a kind of medicine for the treatment of cirrhotic ascites.
Background technology
Cirrhotic ascites, belong to the dropsy scope of the traditional Chinese medical science, the past traditional Chinese medical science thinks that dropsy is one of four large diseases, and think that distension disease is not sick then, a disease then becomes incurable disease.Modern medicine thinks that cirrhotic ascites is the result of many factors comprehensive function, it is the principal element causing ascites that portal hypertension, serum albumin reduce the colloid osmotic pressure reduction caused, Visceral artery expansion causes effective arterial circulation blood volume to decline, activate sympathetic nervous system, RAAS, causing Renal vascular to shrink, is finally cause the unbalanced reason of water and eletrolytes.The method of western medical treatment ascites, mainly controls the absorption of water and sodium salt, and application diuretic, improves plasma colloid osmotic pressure; Also just take to discharge ascites, infusion albumin, liver inside door body drainage to refractory ascites, and self concentrated ascites reinfusion etc., therapeutic effect is not obvious, Chang Fanfu or deterioration, affects the life quality of patient.
Summary of the invention
For the deficiencies in the prior art, the invention provides a kind of medicine for the treatment of cirrhotic ascites.
Technical scheme of the present invention is, a kind of medicine for the treatment of cirrhotic ascites, it is characterized in that, be made up of the raw material of Chinese medicine of following weight portion: Cornu Bubali 6-30 part, Semen Pharbitidis 3-12 part, Semen Pharbitidis 3-12 part; Cortex araliae chinensis root bark 6-30 part, white skin of Radix Sapii Radicis 6-30 part, calabash shell 6-20 part, Herba portulacae 6-30 part, Caulis et folium pavettae hongkongensis 6-30 part.
As optimization, a kind of medicine for the treatment of cirrhotic ascites of the present invention, is characterized in that: be made up of the raw material of Chinese medicine of following weight portion: Cornu Bubali 9 parts, Semen Pharbitidis 6 parts, Semen Pharbitidis 6 parts, Cortex araliae chinensis root bark 30 parts, white skin of Radix Sapii Radicis 30 parts, 9 parts, calabash shell, Herba portulacae 30 parts, Caulis et folium pavettae hongkongensis 30 parts.
The mechanism of action of ingredient of the present invention is as follows: Cornu Bubali: property picric acid is salty-cold, have the effect of heat clearing away dissipating blood stasis, obviously can shorten the bleeding time, reduce erythrocyte sedimentation rate, have excitation to hypophysis one adrenal system.
Semen Pharbitidis: property is bitter, cold, poisonous, have rush down under, diuresis, detumescence effect.
Semen Pharbitidis: property bitter cold, poisonous, have rush down under, diuresis, detumescence effect.
Cortex araliae chinensis root bark: property hardship is put down, have dissipating blood stasis for subsidence of swelling, expelling wind and removing dampness function.
White skin of Radix Sapii Radicis: property bitter cold, slightly poisonous, removing water retention by purgation, dissipating blood stasis for subsidence of swelling.
Calabash shell: property is light flat, diuretic damp eliminating.
Herba portulacae: property acid is cold, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.
Caulis et folium pavettae hongkongensis: sweet, light, micro-pungent, cool, the clearing away heat-damp and promoting diuresis of property.
Liver cirrhosis is the basis of disease, and ascites symptom is mark.Control ascites well, be conducive to treatment and the rehabilitation of liver cirrhosis, explore the medicine that effectively can solve ascites problem, can treat further for liver cirrhosis and precondition is provided.
The traditional Chinese medical science thinks that the etiology and pathogenesis of dropsy disease is complicated, and cold and heat and asthenia and sthenia is also deposited, and involves lung, liver,spleen,kidney four is dirty, the not all right water of lung, the dysfunction of the spleen, and liver blood deposits, and kidney water is not changed; Mend and be then jammed, attack, just hinder, control Fang Yiyong, the product that light clear matter is thin.
Advantage of the present invention: 1, lead to diaphragm dissipating blood stasis with Cornu Bubali removing heat from blood, to disappear diseases caused by retention of fluid with Semen Pharbitidis, removes hydrops between fascia with Cortex araliae chinensis root bark, with white skin of Radix Sapii Radicis, the logical three burnt hydrops of calabash shell, with Herba portulacae, Caulis et folium pavettae hongkongensis removing toxic substances yin nourishing in case just attack profit wound; 2, reached the blood flow improving liver and Portal system by drug regimen combined effect, reduce portal hypertension, opposing angiotensin, increase renal hemodynamic and diuresis catharsis and toxin expelling; Improve liver function, promote albumen synthesis, thus reach the object eliminating ascites fast.3, clinical treatment 45 example facts have proved, evident in efficacy.
Detailed description of the invention
embodiment 1: a kind of medicine for the treatment of cirrhotic ascites, is characterized in that: be made up of the raw material of Chinese medicine of following weight portion: Cornu Bubali 9 parts, Semen Pharbitidis 6 parts, Semen Pharbitidis 6 parts, Cortex araliae chinensis root bark 30 parts, white skin of Radix Sapii Radicis 30 parts, 9 parts, calabash shell, Herba portulacae 30 parts, Caulis et folium pavettae hongkongensis 30 parts.
Preparation method and step: 1, the making of Chinese herbal medicine powder.Cornu Bubali, Semen Pharbitidis, Semen Pharbitidis, calabash shell four taste are beaten powder to sieve 200 orders, make Chinese herbal medicine powder; 2, decocting liquid.Cortex araliae chinensis root bark, white skin of Radix Sapii Radicis, Herba portulacae, Caulis et folium pavettae hongkongensis are placed Chinese medicine extracting tank and decocted three times.First time adds the soak by water 2 hours into Cortex araliae chinensis root bark, white skin of Radix Sapii Radicis, Herba portulacae, Caulis et folium pavettae hongkongensis four Chinese medicine material total amount seven times of weight portions, cross leaching liquid, second time adds the soak by water one and a half hours into Cortex araliae chinensis root bark, white skin of Radix Sapii Radicis, Herba portulacae, Caulis et folium pavettae hongkongensis four Chinese medicine material total amount five times of weight portions, cross leaching liquid, third time adds the soak by water one hour into Cortex araliae chinensis root bark, white skin of Radix Sapii Radicis, Herba portulacae, Caulis et folium pavettae hongkongensis four Chinese medicine material total amount treble amount part, crosses leaching liquid; 3, powder is made.Three of step 2 medicinal liquids merged and be condensed into cream, add the Chinese herbal medicine powder of step 1, drying and crushing is sieved, and namely to obtain powder for subsequent use for 200 orders.
Usage and consumption: the present invention treats liver cirrhosis drug powder, oral 10 grams at every turn, every day three times, ante cibum taken with boiled water or ginger decoction take, within one month, be a course for the treatment of, 1-3 the course for the treatment of can be used depending on the state of an illness.
Clinical treatment is summed up: the present invention, between 1985 to 2010, uses Drug therapy patients with cirrhosis ascites 45 of the present invention example altogether.Wherein male 30 example, women 15 from; The course of disease less than 1 year 20 example, more than 1 year to 5 years 20 example, more than 5 years 5 examples; Through the inventive method treatment ascites disappearance 30 example; Basic disappearance 10; Unchanged 5; Total effective rate is 88.8%.
Model case: 1, Huang Zhe, man, 42 years old, patient was diagnosed as cirrhotic ascites before 2 years, and through therapeutic effect is not obvious repeatedly, patient examines and tells abdominal distention, weak, and inappetence has pain during hepatic region.Health check-up: chronic facies, cervical region, the visible spider angioma in front, the slight xanthochromia of sclera, have liver palm, under abdominal tympanites, liver rib not and, 2cm under spleen rib, abdominal part shifting dullness is positive, and B ultrasonic shows: portal hypertension, splenomegaly, moderate ascites.Give drug powder of the present invention treatment, each 10 grams, every day three times, 30 minutes ante cibum of morning, noon and afternoon taken with boiled water, after taking medicine 12 days, ascites alleviates, then after taking 20 days, ascites disappears substantially, advise its continue conditioning, consolidate curative effect.
2, Lee, man, 65 years old, in May, 1985 cirrhotic ascites hospitalization, treat 20 days poor effect; Find Chinese traditional treatment and go to a doctor, telling distention and fullness in the abdomen pain, inappetence, the tired power of body.Look into abdominal tympanites, epigastric vein varicose, has shifting dullness, and B ultrasonic shows: moderate ascites.Give drug powder of the present invention treatment, each 10 grams, every day three times, 30 minutes ante cibum of morning, noon and afternoon take, taken with boiled water, and after taking medicine 20 days, symptom alleviates, and advise it to continue clothes, and after treating 40 days, B ultrasonic is checked: ascites disappears substantially.Patient mental is good, and appetite is normal, advises it to continue medical treatment.
3, Cui, man, 50 years old, patient's cause inspection in 2 years found hepatitis B; See shallow complexion, limbs fatigue, hepatalgia, companion sees the slight edema of lower limb; To hospital treatment, leave hospital after alleviation.Saw before one month that abdominal part swells, inappetence myasthenia of limbs, show ascites (liver cirrhosis) through ultrasound diagnosis, give powder of the present invention treatment, take medicine one month, symptom takes a turn for the better, but ascites does not disappear completely, after advising it to take medicine one month again, and recovery from illness.

Claims (2)

1. treat a medicine for cirrhotic ascites, it is characterized in that, be made up of the raw material of Chinese medicine of following weight portion: Cornu Bubali 6-30 part, Semen Pharbitidis 3-12 part, Semen Pharbitidis 3-12 part, Cortex araliae chinensis root bark 6-30 part, white skin of Radix Sapii Radicis 6-30 part, calabash shell 6-20 part, Herba portulacae 6-30 part, Caulis et folium pavettae hongkongensis 6-30 part.
2. the medicine for the treatment of cirrhotic ascites according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine of following weight portion: Cornu Bubali 9 parts, Semen Pharbitidis 6 parts, Semen Pharbitidis 6 parts, Cortex araliae chinensis root bark 30 parts, white skin of Radix Sapii Radicis 30 parts, 9 parts, calabash shell, Herba portulacae 30 parts, Caulis et folium pavettae hongkongensis 30 parts.
CN201510950424.9A 2015-12-18 2015-12-18 Medicine for treating ascites due to cirrhosis Pending CN105412205A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110917276A (en) * 2020-01-03 2020-03-27 青岛瑞思德生物科技有限公司 Anti-hepatic fibrosis granule and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279074A (en) * 2000-05-19 2001-01-10 李隆伟 Chinese-medicinal pill 'Ganxuetong'
CN1720974A (en) * 2005-05-29 2006-01-18 王福山 Chinese medicinal composition for treating ascites due to cirrhosis
CN101991810A (en) * 2009-08-25 2011-03-30 王荣春 Medicament for treating hepatitis A and hepatitis B
CN103169838A (en) * 2013-04-12 2013-06-26 严占江 Medicine for treating hepatitis B
CN103656282A (en) * 2013-11-29 2014-03-26 当涂县科辉商贸有限公司 Traditional Chinese medicine composition for treating liver ascites
CN104491068A (en) * 2014-12-21 2015-04-08 莆田市荔城区聚慧科技咨询有限公司 Traditional Chinese medicine composition for treating liver cirrhosis

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279074A (en) * 2000-05-19 2001-01-10 李隆伟 Chinese-medicinal pill 'Ganxuetong'
CN1720974A (en) * 2005-05-29 2006-01-18 王福山 Chinese medicinal composition for treating ascites due to cirrhosis
CN101991810A (en) * 2009-08-25 2011-03-30 王荣春 Medicament for treating hepatitis A and hepatitis B
CN103169838A (en) * 2013-04-12 2013-06-26 严占江 Medicine for treating hepatitis B
CN103656282A (en) * 2013-11-29 2014-03-26 当涂县科辉商贸有限公司 Traditional Chinese medicine composition for treating liver ascites
CN104491068A (en) * 2014-12-21 2015-04-08 莆田市荔城区聚慧科技咨询有限公司 Traditional Chinese medicine composition for treating liver cirrhosis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110917276A (en) * 2020-01-03 2020-03-27 青岛瑞思德生物科技有限公司 Anti-hepatic fibrosis granule and preparation method thereof

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Application publication date: 20160323