CN105381367A - 一种治疗皮肌炎的中药 - Google Patents

一种治疗皮肌炎的中药 Download PDF

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CN105381367A
CN105381367A CN201510986964.2A CN201510986964A CN105381367A CN 105381367 A CN105381367 A CN 105381367A CN 201510986964 A CN201510986964 A CN 201510986964A CN 105381367 A CN105381367 A CN 105381367A
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chinese medicine
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dermatomyositis
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王璐
许璟
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Qingdao Changanda Pharmaceutical Co Ltd
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Abstract

本发明公开了一种治疗皮肌炎的中药，由以下重量份的中药原料制成：山奈45-60份，龙脷叶41-59份，紫花杜鹃33-47份，商陆31-39份，草豆蔻25-34份，平贝母20-31份，灯盏细辛15-24份，麦门冬11-23份，当归5-13份，丹皮8-14份。采用本发明能够有效改善皮肌炎患者临床症状及体征，提高患者的生活质量，有效起到增效减毒、稳定病情的作用；应用本发明的药物治疗皮肌炎的疗效显著，治药物制备及使用方法简单，未发现患者对药品出现不良反应，无毒副作用，标本兼治。

Description

一种治疗皮肌炎的中药
技术领域
本发明涉及一种治疗皮肌炎的中药。
背景技术
皮肌炎（dermatomyositis,DM）又称皮肤异色性皮肌炎（poikilodermatomyositis），属自身免疫性结缔组织疾病之一，是一种主要累及横纹肌，呈以淋巴细胞浸润为主的非化脓性炎症病变，可伴有或不伴有多种皮肤损害，也可伴发各种内脏损害。多发性肌炎（polymyositis,PM）系指本组疾患而无皮肤损害者。
皮肌炎大部分呈慢性进行性发展，预后良好，2～3年内可恢复正常，少部分急性发作者，常因并发感染死亡，并发肿瘤者，也预后极差。皮肤炎属中医的“肌痹”、“痿症”、“虚劳”等范畴。对于皮肌炎的治疗，西医多采用激素和免疫抑制剂治疗，副作用较多，疗效又不甚显著。
发明内容
本发明所要解决的技术问题是：提供一种治疗皮肌炎的药物，本药物为纯中药配方，可以针对皮肌炎，治疗周期短，使用方法简便易行，无毒副作用。
为解决上述技术问题，本发明采用的技术方案是：
本发明提供的一种治疗皮肌炎的中药，由以下重量份的中药原料制成：山奈45-60份，龙脷叶41-59份，紫花杜鹃33-47份，商陆31-39份，草豆蔻25-34份，平贝母20-31份，灯盏细辛15-24份，麦门冬11-23份，当归5-13份，丹皮8-14份。
优选的，本发明提供的中药由以下重量份的中药原料制成：山奈55份，龙脷叶48份，紫花杜鹃40份，商陆35份，草豆蔻31份，平贝母26份，灯盏细辛19份，麦门冬17份，当归9份，丹皮10份。
用法用量：将上述原料用温水浸泡10分钟后，用武火煮沸后再用文火煮30分钟，取药液150毫升，再加水二煎，将两次药液混合后过滤，分两次服用。每天两次，饭后服用。
疗程：15天为一疗程，需服用2-5疗程。
临床资料：
1、病例
选择病例100例，年龄20-65岁，治疗前患者在性别、年龄、病程、病情严重度等方面差异无统计学意义。
2、治疗方法
每天两次服用本发明中药，每次200mL，早晚饭后服用，15天为一个疗程。将其中符合脾肾阳虚，寒湿阻络型中医症候诊断标准的分为S1亚组，其余不符合脾肾阳虚，寒湿阻络型的中医症候诊断标准的分为S2亚组，上述两个亚型均采用相同的治疗措施。治疗2个月。
3、观察指标：
皮疹消退情况、肌力、肌酸磷酸激酶。观察不良反应、复发率与激素的顺利撤减情况。肌力分级标准参照英国医学研究会的分级标准。
4、疗效判定标准：
参照1995年卫生部颁布的《中药新药临床研究指导原则(皮肌炎)》制定。痊愈：皮疹完全消退，肌肉肌力恢复正常，心肌酶恢复正常。
显效：皮疹大部分消退，肌肉肌力增长2-3级，心肌酶中2项或以上测定值下降超过50％。
有效：皮疹部分消退，肌肉肌力增加1-2级，心肌酶有2项或以上下降25-50％。
无效：皮疹无减少，肌力增加不足1级，心肌酶下降均不足25％。
5、治疗结果
100例患者中，临床显效37例，痊愈49例，有效9例，总有效率95%。
采用本发明能够有效改善皮肌炎患者临床症状及体征，提高患者的生活质量，有效起到增效减毒、稳定病情的作用；应用本发明的药物治疗皮肌炎的疗效显著，治药物制备及使用方法简单，未发现患者对药品出现不良反应，无毒副作用，标本兼治。
具体实施方式
实施例1
本实施例提供的治疗皮肌炎的中药，由以下重量份的中药原料制成：山奈55份，龙脷叶48份，紫花杜鹃40份，商陆35份，草豆蔻31份，平贝母26份，灯盏细辛19份，麦门冬17份，当归9份，丹皮10份。
典型病例：
病例1：吴某，男性，61岁，出现肌肉疼痛、无力，抬腿困难，面部后颈出现淡紫红色皮疹，伴有气短、胸闷的症状。使用本发明的中药（实施例1制备）进行治疗，3个疗程后，上述症状得到缓解，皮疹减轻，肌肉疼痛的症状缓解，继续服药2个疗程，上述症状全部消失，至今无复发。
病例2：邓某，女性，52岁，眼睑发红、肿胀，随后面部整体出现红肿，并出现肌无力的症状。服用本发明的中药（实施例1制备）2个疗程后，面部浮肿减轻，后继续服药3个疗程，症状基本消失，肌力恢复，后继续服用2个疗程，痊愈。

Claims (2)

1.一种治疗皮肌炎的中药，其特征在于，由以下重量份的中药原料制成：山奈45-60份，龙脷叶41-59份，紫花杜鹃33-47份，商陆31-39份，草豆蔻25-34份，平贝母20-31份，灯盏细辛15-24份，麦门冬11-23份，当归5-13份，丹皮8-14份。
2.根据权利要求1所述的中药，其特征在于，由以下重量份的中药原料制成：山奈55份，龙脷叶48份，紫花杜鹃40份，商陆35份，草豆蔻31份，平贝母26份，灯盏细辛19份，麦门冬17份，当归9份，丹皮10份。
CN201510986964.2A 2015-12-26 2015-12-26 一种治疗皮肌炎的中药 Pending CN105381367A (zh)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102362972A (zh) * 2011-11-07 2012-02-29 成都绿迪科技有限公司 一种治疗皮肌炎的中药

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102362972A (zh) * 2011-11-07 2012-02-29 成都绿迪科技有限公司 一种治疗皮肌炎的中药

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Application publication date: 20160309