CN105381351A - 用于治疗由肺气不宣引起的小儿哮喘的中药 - Google Patents
用于治疗由肺气不宣引起的小儿哮喘的中药 Download PDFInfo
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Abstract
本发明公开了一种用于治疗由肺气不宣引起的小儿哮喘的中药，主要由下述重量份配比的原料制成：蜂房4-8份，地龙8-12份，桔梗4-8份，苏子10-15份，百部8-12份，天竺黄2-4份，诃子4-8份，甘草3-5份，麻黄4-6份，杏仁4-8份，细辛1-3份，黄芩4-6份。本发明用于治疗由肺气不宣引起的小儿哮喘的中药，选取12种天然中药科学配伍，配方简单，各原料药协同作用起到宣肺降气、祛痰平喘的效果，见效快，标本兼治，无毒副作用，而且其制备方法简单、服用方便，成本低。有效率达到92.5％以上。
Description
技术领域
本发明涉及中药，具体是一种用于治疗由肺气不宣引起的小儿哮喘的中药。
背景技术
支气管哮喘(bronchialasthma)，哮喘是一种表现反复发作性咳嗽，喘鸣和呼吸困难，并伴有气道高反应性的可逆性、梗阻性呼吸道疾病，哮喘是一种严重危害儿童身体健康的常见慢性呼吸道疾病，其发病率高，常表现为反复发作的慢性病程，严重影响了患儿的学习、生活及活动，影响儿童青少年的生长发育，不少儿童哮喘患者由于治疗不及时或治疗不当最终发展为成人哮喘而迁延不愈，肺功能受损，部分患者甚至完全丧失体力活动能力，严重哮喘发作，若未得到及时有效治疗，可以致命，有关哮喘的定义、病因学、发病机制，免疫学、病理生理学及诊断和治疗原则等，儿童与成人基本上相似，但儿童和成人哮喘在某些方面仍然存在着差异。哮喘儿童正处于智能、身体，心理及免疫系统等不断生长发育过程，尤其在免疫学和病理生理学等方面，儿童哮喘有其特殊的方面。世界各地哮喘的发病率在0.1％～32％之间，差异接近300倍，其原因可能与遗传基因，年龄，地理位置，气候，环境，种族，工业化，城市化，室内装修，生活水平，饮食习惯等有关。
起病或急或缓，婴幼儿哮喘发病前往往有1～2天的上呼吸道过敏的症状，包括鼻痒、喷嚏、流清涕、揉眼睛、揉鼻子等表现并逐渐出现咳嗽、喘息。年长儿起病往往较突然，常以阵咳开始，继而出现喘息、呼吸困难等。哮喘急性发作时的主要症状有咳嗽、咳痰或痰鸣、喘息、呼吸困难、胸闷等。典型的表现是发作性伴有哮鸣音的呼气性呼吸困难。轻度发作时多数以发作性咳嗽和胸闷为主要表现。严重发作时患儿烦躁不安，端坐呼吸，耸肩喘息，面色苍白，鼻翼扇动，口唇及指甲青紫，全身冒冷汗，说话时字词不能连续。
现在多以西药治疗为主，但是效果较慢，其副作用大，会引起其他疾病。而目前的一些中药的治疗效率也不甚理想，且疗效不显著。发明内容
本发明的目的是提供一种疗效好、疗程短、成本低、无毒副作用的用于治疗由肺气不宣引起的小儿哮喘的中药。
实现本发明目的的技术方案是：
一种用于治疗由肺气不宣引起的小儿哮喘的中药，主要由下述重量份配比的原料制成：
蜂房4-8份，地龙8-12份，桔梗4-8份，苏子10-15份，百部8-12份，天竺黄2-4份，诃子4-8份，甘草3-5份，麻黄4-6份，杏仁4-8份，细辛1-3份，黄芩4-6份。
上述用于治疗由肺气不宣引起的小儿哮喘的中药，各原料的最佳重量份配比为：
蜂房6份，地龙10份，桔梗6份，苏子12份，百部10份，天竺黄3份，诃子6份，甘草4份，麻黄5份，杏仁6份，细辛2份，黄芩5份。
所述的原料药材在中药店及市场有售。
本发明药物的制备方法如下：按重量配比称取各原料药，加入混合置于容器中，再加原料量重量10-20倍的水煎煮3次，每次煎煮25-30min，合并煎煮液，过滤去渣，滤液浓缩至50-60℃下相对密度为1.20-1.40的浸膏，加入辅料，制成相应的剂型，即得。
本发明中，各原料药的药理、功效如下：
蜂房：具有攻毒杀虫，祛风止痛之功效。常用于疮疡肿毒，乳痈，瘰疬，皮肤顽癣，鹅掌风，牙痛，风湿痹痛。
地龙：具有清热定惊、通络、平喘、利尿的功效。用于高热、神昏、惊痫抽搐、关节痹痛、肺热喘咳、尿少水肿、高血压等症。
桔梗：具有宣肺，利咽，祛痰，排脓的功效。用于咳嗽痰多，胸闷不畅，咽痛音哑，肺痈吐脓。
苏子：降气消痰，止咳平喘，润肠通便。用于痰壅气逆，咳嗽气喘，肠燥便秘。
百部：具有润肺下气止咳，杀虫灭虱之功效。常用于新久咳嗽，肺痨咳嗽，顿咳；外用于头虱，体虱，蛲虫病，阴痒。
天竺黄：具有清热豁痰，凉心定惊的功效。用于热病神昏，中风痰迷，小儿痰热惊痫、抽搐、夜啼。
诃子：具有涩肠止泻，敛肺止咳，降火利咽之功效。常用于久泻久痢，便血脱肛，肺虚喘咳，久嗽不止，咽痛音哑。
甘草：具有补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药之功效。常用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
麻黄：发汗解表，宣肺平喘，利水消肿。风寒表实证，胸闷喘咳，风水浮肿，风湿痹痛，阴疽，痰核。蜜麻黄性温偏润，辛散发汗作用缓和，增强了润肺止咳之功，以宣肺平喘止咳力胜。多用于表症已解，气喘咳嗽。麻黄绒作用缓和，适于老人、幼儿及虚人风寒感冒。蜜麻黄绒作用更为缓和，适于表证已解而喘咳未愈的老人、幼儿及体虚患者。
杏仁：苦温宣肺，润肠通便、仅适宜于风邪、肠燥等实证之患。具有润肺、止咳、滑肠等功效。
细辛：解表散寒，祛风止痛，通窍，温肺化饮。风寒感冒，头痛，牙痛，风湿痹痛，鼻渊，肺寒咳嗽。
黄芩：有清热燥湿、泻火解毒、止血、安胎等功效。主治温热病、上呼吸道感染、肺热咳嗽、湿热黄胆、肺炎、痢疾、咳血、目赤、胎动不安、高血压、痈肿疖疮等症。
本发明用于治疗由肺气不宣引起的小儿哮喘的中药，选取12种天然中药科学配伍，配方简单，各原料药协同作用起到宣肺降气、祛痰平喘的效果，见效快，标本兼治，无毒副作用，而且其制备方法简单、服用方便，成本低。
具体实施方式
下面结合实施例对本发明内容作进一步的说明，但不是对本发明的限定。
实施例1
一种用于治疗由肺气不宣引起的小儿哮喘的中药，主要由下述重量份配比的原料制成：
蜂房4kg，地龙8kg，桔梗4kg，苏子10kg，百部8kg，天竺黄2kg，诃子4kg，甘草3kg，麻黄4kg，杏仁4kg，细辛1kg，黄芩4kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量10倍的水煎煮3次，每次煎煮25min，合并煎煮液，过滤去渣，滤液浓缩至50℃下相对密度为1.20的浸膏，加入辅料，制成片剂，每片0.1g。
实施例2
一种用于治疗由肺气不宣引起的小儿哮喘的中药，主要由下述重量份配比的原料制成：
蜂房6kg，地龙10kg，桔梗6kg，苏子12kg，百部10kg，天竺黄3kg，诃子6kg，甘草4kg，麻黄5kg，杏仁6kg，细辛2kg，黄芩5kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量15倍的水煎煮3次，每次煎煮26min，合并煎煮液，过滤去渣，滤液浓缩至55℃下相对密度为1.20的浸膏，加入辅料，制成片剂，每片0.2g。
实施例3
一种用于治疗由肺气不宣引起的小儿哮喘的中药，主要由下述重量份配比的原料制成：
蜂房8kg，地龙12kg，桔梗8kg，苏子15kg，百部12kg，天竺黄4kg，诃子8kg，甘草5kg，麻黄6kg，杏仁8kg，细辛3kg，黄芩6kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量18倍的水煎煮3次，每次煎煮28min，合并煎煮液，过滤去渣，滤液浓缩至58℃下相对密度为1.30的浸膏，加入辅料，制成丸剂，每粒0.4g。
实施例4
一种用于治疗由肺气不宣引起的小儿哮喘的中药，主要由下述重量份配比的原料制成：
蜂房8kg，地龙12kg，桔梗8kg，苏子15kg，百部12kg，天竺黄4kg，诃子8kg，甘草5kg，麻黄6kg，杏仁8kg，细辛3kg，黄芩6kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量20倍的水煎煮3次，每次煎煮40min，合并煎煮液，过滤去渣，滤液浓缩至60℃下相对密度为1.30的浸膏，加入辅料，制成丸剂，每粒0.5g。
为了进一步证明本发明中药的临床疗效，选择收治患者中的200例，对本发明药物的疗效进行临床观察。年龄2-5岁，随机分为4组，每组为50例，分别为实验组1-4组。
实验组1-4组分别服用实施例1-4的药物，每日2次，每次内服3片/粒，5天为一个疗程，连续服用2个疗程。其中显效180例，有效185例，治愈175例，无效15例，治愈率87.5％，有效率92.5％。
Claims (3)
1.一种用于治疗由肺气不宣引起的小儿哮喘的中药，其特征是：主要由下述重量份配比的原料制成：
蜂房4-8份，地龙8-12份，桔梗4-8份，苏子10-15份，百部8-12份，天竺黄2-4份，诃子4-8份，甘草3-5份，麻黄4-6份，杏仁4-8份，细辛1-3份，黄芩4-6份。
2.根据权利要求1所述的用于治疗由肺气不宣引起的小儿哮喘的中药，其特征是：各原料的最佳重量份配比为：
蜂房6份，地龙10份，桔梗6份，苏子12份，百部10份，天竺黄3份，诃子6份，甘草4份，麻黄5份，杏仁6份，细辛2份，黄芩5份。
3.根据权利要求1所述的用于治疗由肺气不宣引起的小儿哮喘的中药，其特征是：
制备方法如下：按重量配比称取各原料药，加入混合置于容器中，再加原料量重量10-20倍的水煎煮3次，每次煎煮25-30min，合并煎煮液，过滤去渣，滤液浓缩至50-60℃下相对密度为1.20-1.40的浸膏，加入辅料，制成相应的剂型，即得。
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