CN105381338A - 一组治疗多形红斑的药物 - Google Patents

一组治疗多形红斑的药物 Download PDF

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CN105381338A
CN105381338A CN201510839345.0A CN201510839345A CN105381338A CN 105381338 A CN105381338 A CN 105381338A CN 201510839345 A CN201510839345 A CN 201510839345A CN 105381338 A CN105381338 A CN 105381338A
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黄德禄
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Abstract

本发明涉及一组治疗多形红斑的药物,医药技术领域,解决多形红斑病情复杂,易于复发的问题,通过以中医学观点分析多形红斑,属于脾肺虚弱,风毒入血,湿热蕴结,发于肌肤,采取以健脾祛湿、清热拔毒、疏风凉血之中药结合作治药物:绿豆份15份、生地15份、金银花10份、全蝎15份、丹皮10份、皂角刺15份、生麦芽10份、菊花10份、芥籽10份、黄芩15份、黄精10份、枸杞子10份、连翘15份、桑叶15份、甘草10份。一组治疗多形红斑的药物应用于治疗效果显著,复发率少。

Description

一组治疗多形红斑的药物
技术领域
本发明涉及一组治疗重症多型红斑的药物,属于医学技术领域。
背景技术
多形红斑为急性炎症性皮肤病,有自限性,皮疹多形,有红斑、丘疹、风团、水疱等,特征性皮损为靶形损害即虹膜状皮疹,有不同程度黏膜损害,少数有内脏损害。本病春秋季好发,男性略多于女性,以10~30岁发病率最高,20%为青少年。重症多形红斑即为多形红斑发展扩展至全身严重的症状。
重症多形红斑的临床表现:前驱症状有头痛、发热、四肢倦怠、食欲不振、关节和肌肉酸痛、扁桃体炎及呼吸道感染等症状。皮疹多形,有红斑、丘疹、风团、水疱、大疱和紫癜等。临床分3型:1.红斑丘疹型,最常见,为轻症型,多与单纯疱疹病毒感染有关。皮疹以红斑、丘疹为主,亦见风团,分布于四肢末端伸侧面。充分发展的红斑可形成靶形损害。皮疹光照后加重,可出现同形反应,有轻度瘙痒,黏膜损害轻,常局限于口腔黏膜。2.局限水疱型,介于轻症和重症之间。皮疹以水疱为主,红斑中央有水疱或红斑为水疱围绕,皮疹数目不多,局限于四肢末端部位,有黏膜损害。3.重症型,发病前有前驱症状,红斑数目多,主要分布于四肢,常扩散至躯干,有多数典型的靶形损害,有发热,黏膜损害严重,可累及2个部位的黏膜,全身浅表淋巴结增大。
多形红斑的诊断:本病皮疹多形,有典型的靶形损害,好发于四肢末端,对称分布,有黏膜损害,重症者有发热等全身症状,组织病理上有个别角质形成细胞坏死,合并HSV感染时皮损部位HSV抗原检测阳性。
多形红斑的治疗:1.病因治疗,病因明确者,针对病因治疗。2.局部治疗,对皮损应用清洁、保护、止痒、温和消炎剂,如植物油、炉甘石洗剂、氧化锌油剂、硅油霜、糖皮质激素软膏等。口腔病变应用含漱剂,保持口腔清洁。眼部病变及早请眼科会诊。肛门、尿道口及外生殖器部位可用0.05%氯己定液清洁,有感染时及时应用抗生素。3.全身治疗,(1)口服抗组胺药、多种维生素,重症者补充水分和营养,保持水、电解质的平衡。(2)对重症型病例早期、短程、系统应用糖皮质激素可及时控制病情发展,减轻症状和缩短病程。(3)重症型病例可静脉注射免疫球蛋白治疗,尤其适用于糖皮质激素疗效不佳或有糖皮质激素禁忌证者。(4)其他:包括应用左旋咪唑、环磷酰胺、环孢素、氨苯砜、沙利度胺等。西药治疗复发性高。
发明内容
多形红斑是一种免疫性疾病,病人常表现脾运衰弱、反应敏感。以中医学观点分析多形红斑,属于脾肺虚弱,风毒入血,湿热蕴结,发于肌肤,治疗应以健脾祛湿、清热拔毒、疏风凉血之中药结合作治药物。
一组治疗多形红斑的药物是按下面各中药质量比组合而成:绿豆份15份、生地15份、金银花10份、全蝎15份、丹皮10份、皂角刺15份、生麦芽10份、菊花10份、芥籽10份、黄芩15份、黄精10份、枸杞子10份、连翘15份、桑叶15份、甘草10份。
下面分析一组治疗多形红斑的药物中各中药成分的药性功效。绿豆性凉味甘,有清热解毒、止渴消暑、利尿润肤的功效,绿豆的抗病毒功效显著。生地清热生津,凉血,止血,用于热病伤阴,舌绛烦渴,发斑发疹,吐血,衄血,咽喉肿痛。金银花自古被中医誉为清热解毒的良药,金银花的茎、叶和花都可入药,具有解毒、消炎、杀毒、杀菌、利尿和止痒的作用。全蝎归为平肝息风药,其味辛,性平,有毒,归肝经,具有息风止痉、通络止痛、解毒散结的功效。丹皮归心,清热凉血、活血散瘀、滋阴降火、利咽喉、通小便、抗炎、镇静、降温。皂角刺有消肿排脓、消毒透脓、搜风、杀虫的功效。生麦芽健脾和胃,疏肝行气,用于脾虚食少,乳汁郁积。菊花功效,具有散风清热、平肝明目之功效,用于治疗风热感冒、头痛眩晕、目赤肿痛、眼目昏花。芥菜籽有宣肺豁痰,利气温中,解毒消肿,开胃消食,温中利气,明目利膈;主治咳嗽痰滞、胸隔满闷、疮痈肿痛、耳目失聪、牙龈肿烂、寒腹痛、便秘等病症。黄芩清热燥湿、泻火解毒、安胎、抗氧化、抗病毒、抗菌。黄精属滋补药,入脾,滋阴润肺,养血,润心肺,消渴,治阴虚劳嗽,肺燥咳嗽,脾虚乏力,食少口干,消渴,肾亏腰膝酸软,阳痿遗精,耳鸣目暗,须发早白,体虚赢瘦,风癞癣疾。枸杞子可调节机体免疫功能、能有效抑制肿瘤生长和细胞突变、具有延缓衰老、抗脂肪肝、调节血脂和血糖、促进造血功能等方面的作用。连翘是一味中药,味苦性寒,具有清热,解毒,散结,消肿之功效;常用于治疗温热,丹毒,斑疹,痈疡肿毒,瘰疬,小便淋闭等症状。桑叶的功效:疏散风热,清肺润燥,清肝明目;用于风热感冒,肺热燥咳,头晕头痛,目赤昏花。甘草性平,味甘,归十二经;有解毒、祛痰、止痛、解痉以至抗癌等药理作用;在中医上,甘草补脾益气,滋咳润肺,缓急解毒,调和百药。
一组治疗多形红斑的药物发明的有益效果是:通过以中医学观点分析多形红斑,属于脾肺虚弱,风毒入血,湿热蕴结,发于肌肤,采取以健脾祛湿、清热拔毒、疏风凉血之中药结合作治药物,应用效果显著,复发率少。
具体实施方式
下面以适合于一个多形红斑患者服用量作为优选实施例作进一步的说明。
一组治疗多形红斑的药物适用于一个多形红斑患者服用的一个剂量药量是按下面各中药质量组合而成:绿豆份15克、生地15克、金银花10克、全蝎15克、丹皮10克、皂角刺15克、生麦芽10克、菊花10克、芥籽10克、黄芩15克、黄精10克、枸杞子10克、连翘15克、桑叶15克、甘草10克。使用方法:煎汤内服,日服一个剂量,症状减轻后可两日服用一个剂量,直至痊愈。

Claims (1)

1.一组治疗多形红斑的药物,其特征是按下面各中药质量比组合而成:绿豆份15份、生地15份、金银花10份、全蝎15份、丹皮10份、皂角刺15份、生麦芽10份、菊花10份、芥籽10份、黄芩15份、黄精10份、枸杞子10份、连翘15份、桑叶15份、甘草10份。
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN105748999A (zh) * 2016-03-31 2016-07-13 广州暨南生物医药研究开发基地有限公司 含艾叶的治疗寒冷性多形红斑的中药组合物及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
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