CN105378100B - 流体装置的新用途 - Google Patents

流体装置的新用途 Download PDF

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Publication number
CN105378100B
CN105378100B CN201480038969.6A CN201480038969A CN105378100B CN 105378100 B CN105378100 B CN 105378100B CN 201480038969 A CN201480038969 A CN 201480038969A CN 105378100 B CN105378100 B CN 105378100B
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concentration
bactericide
fluid
bacteriostatic agent
culture substrate
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Chinese (zh)
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CN105378100A (zh
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J·克雷于格
S·索斯朗德
吴志刚
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Gradientech AB
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Gradientech AB
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/16—Apparatus for enzymology or microbiology containing, or adapted to contain, solid media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201480038969.6A 2013-07-10 2014-07-10 流体装置的新用途 Active CN105378100B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1350861 2013-07-10
SE1350861-9 2013-07-10
PCT/SE2014/050883 WO2015005863A1 (en) 2013-07-10 2014-07-10 New use of a fluidic device

Publications (2)

Publication Number Publication Date
CN105378100A CN105378100A (zh) 2016-03-02
CN105378100B true CN105378100B (zh) 2019-05-28

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CN201480038969.6A Active CN105378100B (zh) 2013-07-10 2014-07-10 流体装置的新用途

Country Status (5)

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US (2) US10487349B2 (enExample)
EP (1) EP3019625B1 (enExample)
JP (1) JP6321158B2 (enExample)
CN (1) CN105378100B (enExample)
WO (1) WO2015005863A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018144431A1 (en) 2017-02-02 2018-08-09 PhAST Corp. Analyzing and using motility kinematics of microorganisms
SG11202011180UA (en) * 2018-05-31 2020-12-30 Berkeley Lights Inc Automated detection and characterization of micro-objects in microfluidic devices
JP7553963B2 (ja) * 2019-04-03 2024-09-19 グラディエンテク エービー カセットアセンブリ
CN111403636B (zh) * 2020-03-27 2021-01-12 苏州清陶新能源科技有限公司 一种电池用软壳、其制备方法和用途
EP4001397A1 (en) 2020-11-19 2022-05-25 Real Research Sp. z o.o. Cuvette, cassette and system for macroscale 3d growth and treatment of cells
CN112430542B (zh) * 2020-11-25 2022-06-14 中南大学 集成微流控三维肿瘤芯片及仿生方法
WO2025048699A1 (en) 2023-08-30 2025-03-06 Gradientech Ab Resistance and/or resistance mechanism prediction

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009061392A1 (en) * 2007-11-05 2009-05-14 President And Fellows Of Harvard College Forming gel structures using microfluidic channels
WO2010018499A1 (en) * 2008-08-11 2010-02-18 Koninklijke Philips Electronics N.V. Apparatus and method for performing cellular susceptibility testing
WO2010056186A1 (en) * 2008-11-17 2010-05-20 Gradientech Ab Fluidic culture device
WO2012050981A1 (en) * 2010-09-29 2012-04-19 Massachusetts Institute Of Technology Device for high throughput investigations of cellular interactions

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
US6153400A (en) * 1999-03-12 2000-11-28 Akzo Nobel N.V. Device and method for microbial antibiotic susceptibility testing
WO2007044888A2 (en) * 2005-10-11 2007-04-19 The Johns Hopkins Univerisity Microfluidic device and method for high-throughput cellular gradient and dose response studies
JP5602718B2 (ja) 2008-04-08 2014-10-08 マサチューセッツ インスティテュート オブ テクノロジー 三次元マイクロ流体プラットホームおよびその使用方法
WO2009152389A2 (en) * 2008-06-11 2009-12-17 Katzenelson Omer Y Systems and methods to perform inhibition diagnostic testing
US8216526B2 (en) * 2008-06-17 2012-07-10 The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology Method and device for generating diffusive gradients in a microfluidic chamber
WO2010129532A2 (en) * 2009-05-05 2010-11-11 Trustees Of Boston University Method and device for rapid detection of bacterial antibiotic resistance/susceptibility
US20110186165A1 (en) 2009-10-05 2011-08-04 Borenstein Jeffrey T Three-dimensional microfluidic platforms and methods of use and manufacture thereof
US9353342B2 (en) 2010-01-21 2016-05-31 Emd Millipore Corporation Cell culture and gradient migration assay methods and devices
JP5881031B2 (ja) 2010-03-18 2016-03-09 国立研究開発法人産業技術総合研究所 薬剤感受性試験用バイオチップ
US8828332B2 (en) 2010-09-10 2014-09-09 Gradientech Ab Microfluidic capsule

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009061392A1 (en) * 2007-11-05 2009-05-14 President And Fellows Of Harvard College Forming gel structures using microfluidic channels
WO2010018499A1 (en) * 2008-08-11 2010-02-18 Koninklijke Philips Electronics N.V. Apparatus and method for performing cellular susceptibility testing
WO2010056186A1 (en) * 2008-11-17 2010-05-20 Gradientech Ab Fluidic culture device
WO2012050981A1 (en) * 2010-09-29 2012-04-19 Massachusetts Institute Of Technology Device for high throughput investigations of cellular interactions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
An agarose-based microfluidic platform with a gradient buffer for 3D chemotaxis studies;Haessler U et al.;《Biomedical microdevices》;20090403;第11卷(第4期);第827-835页 *

Also Published As

Publication number Publication date
US10487349B2 (en) 2019-11-26
EP3019625A4 (en) 2017-03-15
US20200048680A1 (en) 2020-02-13
US20160186231A1 (en) 2016-06-30
EP3019625A1 (en) 2016-05-18
JP6321158B2 (ja) 2018-05-09
EP3019625B1 (en) 2018-02-21
JP2016523105A (ja) 2016-08-08
CN105378100A (zh) 2016-03-02
WO2015005863A1 (en) 2015-01-15
US11427851B2 (en) 2022-08-30

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