CN1053729A - A kind of antimicrobial and preparation method thereof - Google Patents

A kind of antimicrobial and preparation method thereof Download PDF

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Publication number
CN1053729A
CN1053729A CN90100524A CN90100524A CN1053729A CN 1053729 A CN1053729 A CN 1053729A CN 90100524 A CN90100524 A CN 90100524A CN 90100524 A CN90100524 A CN 90100524A CN 1053729 A CN1053729 A CN 1053729A
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urea
kitchen garden
juice
auxiliary material
preparation
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CN90100524A
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王国华
徐芝庭
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XU ZHITING WANG GUOHUA
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XU ZHITING WANG GUOHUA
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Priority to CN90100524A priority Critical patent/CN1053729A/en
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Abstract

A kind of antimicrobial and preparation method thereof, effective component extracting in the kitchen garden herb adds urea and auxiliary material.The antimicrobial that obtains can suppress broad spectrum fungus, is applicable to people and domestic animals and fowls control fungal disease; Can make antibiotic composition pesticide, make plant protection, growth stimulator, controlling plant diseases is free from environmental pollution again, and cover crop is not with harmful substances; Can make domestic animal poultry feed antibacterial additives, roughage reaches protamine matter feed after adding additive, has the feeding effect of concentrated feed, saves food, and reduces significantly and feeds cost, and can prevent and treat diseases such as domestic animals and fowls coccidiosis, dysentery characterized by white mucous stool.

Description

A kind of antimicrobial and preparation method thereof
The invention belongs to medical, agricultural antimicrobial technical field.Especially antimycotic, plant protection, field of feed additive technology.
The kitchen garden herb traditional Chinese medical science think have clearing heat and detoxicating, the effect of the blood detumescence of loosing etc., modern pharmacological research proves that it has antibacterial action.The kitchen garden ethanol extract has significant inhibitory effect to will Hayes and the secondary dysentery characterized by blood in the stool bacillus of Fo Shi, and water decoction also all has inhibitory action to will Hayes, ancestor Nei Shi, Si Shi and Fei Shi shigella dysenteriae.But broad spectrum fungus and other bacteriums are still found no inhibitory action.
The present invention overcomes above-mentioned kitchen garden antibacterial action weak point, prepares a kind of antimicrobial.Under total inventive concept, antimicrobial has has obvious inhibitory action to broad spectrum fungus; Crops there is protection, helps the growth effect; Some disease to domestic animals and fowls has treatment and prevention effect; The domestic animals and fowls feed is replenished antibacterial additives, become the good protein feed, make feed cost that obvious reduction be arranged.In a word, the present invention has obvious effects and wide purposes.
Antimicrobial of the present invention mainly contains kitchen garden herb and urea, content by weight, kitchen garden herb juice is 40%-70%, urea is 30%-60%, can increase auxiliary material in order to improve usefulness, and auxiliary material is a honeysuckle, or dark plum or granatum, its content respectively is 0.5-1%, selects on demand in its a kind of adding key component, perhaps selects honeysuckle and dark plum to add simultaneously.When adding auxiliary material, kitchen garden herb juice is 39-70%, and urea is 29-60%.Its preparation method is as follows:
A. the fresh purslane herb of cleaning is pulverized.
B. extract kitchen garden herb juice.
C. kitchen garden juice is poured in the reaction pot and is heated, add urea and stir, keep heating temperature, content by weight, kitchen garden juice is 39-70%, urea is 29-60%, adds Powdered auxiliary material at last, stirs.
D. separating liquid material and deposit.
Its juice is pulverized and extracted to the fresh purslane herb after choosing, cleaning, and pours kitchen garden juice into reaction pot, is warmed to 30-40 ℃ under normal pressure, add urea, keep heating temperature, stir simultaneously, and the adding auxiliary material, the speed of stirring is only otherwise making to mix with the chemical combination species precipitate gets final product.The weight ratio of kitchen garden juice and silk tree, when preferable states, kitchen garden juice is 45-55%, urea is 45-55%.When adding auxiliary material, kitchen garden juice, urea respectively are 44-55%.Kitchen garden juice, urea and auxiliary material in reaction pot, mix with chemical combination after, with seperator separating liquid material and deposit.Liquid substance is antibiotic composition pesticide, also is antimicrobial medical, for animals.Deposit is an antimicrobial medical, for animals.The present invention mainly is the antimicrobial that suppresses broad spectrum fungus, and some protozoon, bacterium are had certain inhibitory action, can be used as for oral administration and topical drug.
Under total inventive concept, the present invention is antibiotic composition pesticide, it is characterized in that containing kitchen garden herb juice and urea, its content weight ratio, and kitchen garden juice is 40-70%, urea is 30-60%.For improving drug effect, can add auxiliary material, auxiliary material is honeysuckle or dark plum, perhaps honeysuckle and dark plum, its content respectively is 0.5-1%.When adding auxiliary material, kitchen garden juice is 39-70%, and urea is 29-60%.During preferable states, kitchen garden juice is 45-55%, and urea is 45-55%.When adding auxiliary material, juice, urea respectively are 44-55%.Antibiotic composition pesticide is not only antibacterials, and is plant growth substance.The preparation method of antibiotic composition pesticide: be above-mentioned a.b.c. method, and the liquid substance that obtains after separating.The temperature of heating is 30-40 ℃, heats under normal pressure.Composition pesticide of the present invention is nontoxic, and is free from environmental pollution, is not with on the crops with harmful substances, safe in utilization, promotes plant growing, and cost is low, compares with antibiotic, and pharmacy output is big, saves a large amount of grains, and cost obviously descends.
Under total inventive concept, the present invention adjust key component content the poultry and livestock feed antibacterial additives, the feature of feed antibacterial additives is to contain kitchen garden herb and urea, its weight ratio, the kitchen garden herb is 70-90%, urea is 10-30%.Imitate for improving to feed, can increase auxiliary material, auxiliary material is honeysuckle or dark plum, or honeysuckle and dark plum, and its content weight ratio respectively is 0.5-1%.When adding auxiliary material, herb is 69-90%, and urea is 9-30%.Its preparation method is as follows:
E. the fresh purslane herb of cleaning is pulverized.
F. add urea in the kitchen garden herb of pulverizing, the stirring of heating adds Powdered auxiliary material then and stirs evenly.
Perhaps add urea and Powdered auxiliary material in the slag after the extraction kitchen garden herb juice in the a.b. method, by weight, slag is 92-97%, and urea is 2-7%, and auxiliary material is 0.5-1%.Auxiliary material is honeysuckle or dark plum, or the honeysuckle and the root of three-nerved spicebush.
The temperature of heating in preparation process is 30-40 ℃, heats under normal pressure.Auxiliary material is honeysuckle or dark plum, or honeysuckle and dark plum, and its content respectively is 0.5-1%.In roughage, add antibacterial additives, become the good protein feed, can reach the effect that concentrated feed is fed, make the cost of feed that obvious reduction be arranged.And the domestic birds and animals of feeding the antibacterial additives feed has obvious prophylactic resistance.Grow for quickening domestic animals and fowls, also can add mineral trace element.
Embodiment:
1) the present invention is an example with the externally applied drug that suppresses broad spectrum fungus, treatment foot, the tinea manuum, onychomycosis.With the medicine that above-mentioned a.b.c.d. method obtains, its weight ratio, kitchen garden juice is 46-53%, and urea is 46-53%, and auxiliary material honeysuckle or dark plum are 0.5-1%.Get the liquid substance after the separation, smear the affected part, smear the affected part after also available liquid and deposit shake up, also available deposit is smeared the affected part separately.Deposit is stronger than liquid substance sterilizing power.General treatment tinea pedis, the tinea manuum are coated with 1-2 time every day, need cure approximately in 6 days to 12 days.This medicine has special efficacy to feet rhagades, and smear affected part 1-2 time with liquid substance every day, and a general week just can cure, and if any repetitiousness, is coated with 1-2 days again and just can cures after the drug withdrawal.This medicine does not have peculiar smell, does not pollute clothing, socks, and being applied to the affected part need not wrap up, easy to use.If auxiliary material adopts granatum, can make hemostatic usefulness, hemostasis immediately after shallow, minor cut or wound etc. coated.
2) liquid medicine of obtaining with above-mentioned a.b.c.d. method, its weight ratio, kitchen garden juice is 46-53%, and urea is 46-53%, and auxiliary material is honeysuckle 0.5-1%, in order to the treatment chicken coccidiasis.Have 18 fryer to suffer from coccidiosis, chicken droppings is blood red, between about 0.8 kilogram to 1 kilogram of the weight of every chicken, admixes 0.13 kilogram of liquid substance antimicrobial every day in feed, feeds after 5 days because the antimicrobial good palatability, and fryer is emulatively eaten food; The good drug efficacy chicken droppings is normal fully, has cured the coccidiosis of chicken.Because be liquid substance, in feed, stir easily during dispenser, be difficult for making disease chicken excess to take medicine and cause and be poisoned to death, price is also than existing cheap with medicine.
3) be subjected to fungus attack in Beijing suburbs and counties under the jurisdiction of a large city Chinese cabbage vegetable plot, use above-mentioned a.b.c.d. method, the liquid antibiotic agricultural chemicals of preparation, its auxiliary material are that honeysuckle or dark plum content are 0.5-1%, all the other are that key component kitchen garden juice is 46-53%, and urea is 46-53%.Nine row Chinese Cabbage are tested as dispenser with the liquid antibiotic agricultural chemicals, insecticide-applying way is with the agricultural chemicals dilute with water, be sprayed on the dish leaf, make liquid pesticidal directly for leaf absorbs, improve drug effect, the ratio of liquid pesticidal dilution is 8-12%, per 7 days spray medicines once, spray medicine altogether three times, controlled the dish disease, and from then on nine row Chinese cabbages rise and blocked spreading of disease.Through the Chinese cabbage of spray medicine, dish leaf lines is obvious, and color is dark, when gathering in the crops after one month, relatively to have quality good with other Chinese cabbages, Heavy Weight: the cabbage leaf plumpness, and Bao Xinda and reality, the big Qing Gang is seldom, storage tolerance does not come off, and every Chinese cabbage weight is about the 6-7 kilogram.Through enforcement, this composition pesticide has the effect of control vegetable fungi disease; Promote the modulator effect of plant growing; The effect of enriching nutrient is provided.Biggest advantage, itself does not contain hazardous substance composition pesticide, and is free from environmental pollution, does not have contamination on the vegetables, does not have subsidiary harmful substance, edible safety.Only from the environmental protection aspect, wideling popularize non-poisonous pesticides also has far reaching significance.
4) domestic animals and fowls feed ingredient and content have nothing in common with each other, so the composition of batching is also different.This example is with adding antibacterial additives in the roughage, become the good protein feed, substitute concentrated feed, and obtain identical feeding effect, the nursing cost of domestic animals and fowls being reduced significantly.This example obtains antibacterial additives with above-mentioned e.f. preparation method and is added in and feeds fryer in the pig feed.The weight ratio of additive level, kitchen garden herb are 83-87%, and urea is 12-16%, and auxiliary material honeysuckle or dark plum are 0.5-1%.Under the identical situation of feeding conditions, the put on flesh weight and hello the broiler fodder basically identical of fryer, increase weight about 0.05 kilogram general every day.The additivated price of pig feed only accounts for the 35%-40% of broiler fodder price, adapted phytoprotein in the broiler fodder, raw material sources difficulty, valency height.Can utilize the chemical composition of additive now, make feed become the good protein feed, feed cost be reduced, and can save grain, the advantage of prevention domestic birds and animals disease.
Advantage of the present invention: 1) the present invention is under total inventive concept, and of many uses, effect is remarkable, and the preparation method is easy, and nontoxic, side effect is of far-reaching significance from environmental protection and joint grain. 2) antimicrobial mainly is to suppress broad spectrum fungus, and some protozoon, bacterium are had certain inhibitory action, and purposes is wider, and the developing of continuation prospect is arranged. 3) antibiotic agricultural chemicals is free from environmental pollution, does not have contamination on the crops, does not have band with harmful substances, have again the Promoting plant growth function simultaneously, and cost is low, and this existing agricultural chemicals can't be compared. Compare with antibiotic, it is big that antibiotic agricultural chemicals has output, and cost is low, saves a large amount of grains. 4) feed antibacterial additives of the present invention can prevent and treat the domestic animals and fowls disease, improves the feed good protein and reduces significantly feed cost.
Figure 90100524X_IMG1

Claims (13)

1, a kind of preparation method of antimicrobial is characterized in that:
A. the fresh purslane herb of cleaning is pulverized,
B. extract juice in the kitchen garden herb,
C. pour kitchen garden juice into reaction pot and heat, add urea and stir, keep heating temperature, content by weight, kitchen garden juice is 39-70%, urea is 29-60%, adds Powdered auxiliary material at last, stir,
D. separating liquid material and deposit.
2, the preparation method of antimicrobial according to claim 1 is characterized in that it is 30-40 ℃ that kitchen garden juice is poured the temperature that reaction pot heats into, heats under normal pressure.
3, the preparation method of antimicrobial according to claim 1 is characterized in that the weight ratio of kitchen garden juice and urea, and when preferable states, kitchen garden juice is 44-55%, and urea is 44-55%.
4, the preparation method of antimicrobial according to claim 1 is characterized in that auxiliary material is a honeysuckle, or dark plum, or granatum, perhaps honeysuckle and dark plum, and its content weight ratio respectively is 0.5-1%.
5, a kind of antibiotic composition pesticide is characterized in that containing kitchen garden herb juice and urea, its content weight ratio, and kitchen garden juice is 39-70%, urea is 29-60%.
6, antibiotic composition pesticide according to claim 5, when it is characterized in that antibiotic composition pesticide performance preferable states, its content by weight, kitchen garden juice is 44-55%, urea is 44-55%.
7, antibiotic composition pesticide according to claim 5 is characterized in that adding auxiliary material, and auxiliary material is a honeysuckle, or dark plum, or honeysuckle and dark plum, and its content respectively is 0.5-1%.
8, a kind of preparation method of antibiotic composition pesticide is characterized in that according to the a.b.c. method in the claim 1, and separation obtains liquid substance.
9, the preparation method of antibiotic composition pesticide according to claim 8 is characterized in that it is 30-40 ℃ that kitchen garden juice is poured the temperature that reaction pot heats into, heats under normal pressure.
10, a kind of domestic animals and fowls feed antibacterial additives is characterized in that containing kitchen garden herb and urea, its content weight ratio, and the kitchen garden herb is 69-90%, urea is 9-30%.
11, antibacterial additives according to claim 10 is characterized in that increasing auxiliary material, and auxiliary material is honeysuckle or dark plum, or honeysuckle and dark plum, and its content weight ratio respectively is 0.5-1%.
12, a kind of preparation method of domestic animals and fowls feed antibacterial additives is characterized in that
E. the fresh purslane herb of cleaning is pulverized,
F. add urea in the kitchen garden herb of pulverizing, heating stirs, and adds Powdered auxiliary material then and stirs evenly, and presses the content weight ratio, and the kitchen garden herb after the pulverizing is 69-90%, and urea is 9-30%,
Perhaps in the slag after the extraction kitchen garden herb juice, add urea and Powdered auxiliary material in the a.b. method, heating stirs, and by weight, slag is 92-97%, and urea is 2-7%, and auxiliary material is 0.5-1%, and auxiliary material is honeysuckle or dark plum.
13, the preparation method of antibacterial additives according to claim 12, the temperature that it is characterized in that heating is 30-40 ℃, heats under normal pressure.
CN90100524A 1990-02-05 1990-02-05 A kind of antimicrobial and preparation method thereof Pending CN1053729A (en)

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Application Number Priority Date Filing Date Title
CN90100524A CN1053729A (en) 1990-02-05 1990-02-05 A kind of antimicrobial and preparation method thereof

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CN1053729A true CN1053729A (en) 1991-08-14

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006013001A1 (en) * 2004-08-06 2006-02-09 Indena S.P.A The use of medicinal plants and extracts thereof for the well-being of animals in veterinary medicine and zootechnics
CN101411539B (en) * 2007-10-19 2011-11-30 裵芝贤 Antimicrobial film composition adding with portulaca oleracea extract, and ntimicrobial film, coatings and spray solution prepared therefrom
CN106234443A (en) * 2016-08-10 2016-12-21 吴远宁 A kind of mango antibacterial and preparation method thereof
CN107072218A (en) * 2014-12-22 2017-08-18 Mc食品科技株式会社 Bacterial multiplication suppressing method in antiseptic and diet product
CN112717085A (en) * 2021-03-04 2021-04-30 肖红远 Traditional Chinese medicine composition for treating tinea manus and pedis and preparation method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006013001A1 (en) * 2004-08-06 2006-02-09 Indena S.P.A The use of medicinal plants and extracts thereof for the well-being of animals in veterinary medicine and zootechnics
CN101411539B (en) * 2007-10-19 2011-11-30 裵芝贤 Antimicrobial film composition adding with portulaca oleracea extract, and ntimicrobial film, coatings and spray solution prepared therefrom
CN107072218A (en) * 2014-12-22 2017-08-18 Mc食品科技株式会社 Bacterial multiplication suppressing method in antiseptic and diet product
CN107072218B (en) * 2014-12-22 2020-12-08 Mc食品科技株式会社 Antibacterial agent and method for inhibiting bacterial growth in food or beverage
CN106234443A (en) * 2016-08-10 2016-12-21 吴远宁 A kind of mango antibacterial and preparation method thereof
CN112717085A (en) * 2021-03-04 2021-04-30 肖红远 Traditional Chinese medicine composition for treating tinea manus and pedis and preparation method thereof

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