CN105362348A - Traditional Chinese medicine composition for treating migraine - Google Patents

Traditional Chinese medicine composition for treating migraine Download PDF

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Publication number
CN105362348A
CN105362348A CN201510979638.9A CN201510979638A CN105362348A CN 105362348 A CN105362348 A CN 105362348A CN 201510979638 A CN201510979638 A CN 201510979638A CN 105362348 A CN105362348 A CN 105362348A
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parts
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chinese medicine
medicine composition
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曲宗凤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/407—Liver; Hepatocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)

Abstract

The invention discloses a traditional Chinese medicine composition for treating migraine. The traditional Chinese medicine composition is prepared from the following active pharmaceutical ingredients: 6 parts of angelica dahurica, 6 parts of chrysanthemum, 5 parts of radix saposhnikoviae, 8 parts of angelica, 5 parts of panax notoginseng, 4 parts of Szechuan lovage rhizome, 3 parts of asarum, 9 parts of broom cypress fruits, 7 parts of selfheal, 8 parts of notopterygium roots, 6 parts of dwarf lilyturf turber, 6 parts of oysters, 5 parts of semen cassiae, 7 parts of radix bupleuri and 10 parts of radix glycyrrhizae. The traditional Chinese medicine is reasonable in compatibility; all the active pharmaceutical ingredients have the synergistic effect, so that the traditional Chinese medicine composition has the efficacies of expelling wind to remove cold, clearing away heat to remove dampness, calming liver wind, and activating collaterals to dissipate phlegm, can treat migraine fundamentally, and is high in cure rate, high in efficiency, short in treatment course, low in cost and free of side effects.

Description

One treats migrainous Chinese medicine composition
Technical field
The invention belongs to technical field of Chinese medicines, one treats migrainous Chinese medicine composition specifically.
Background technology
Migraine is clinical modal primary headache type; clinical with ictal middle severe, sample of beating headache for main manifestations; headache mostly is inclined side; general lasting 4 ~ 72 hours; can with Nausea and vomiting; light, Sound stimulat or daily routines all can increase the weight of headache, and quiet environment, rest can alleviate headache.
Migraine is a kind of common chronic forms vascular illness, and a lot of disease is in child and adolescence, and the young and middle-aged phase reaches onset peak, and women is common, and men and women's Proportion of patients is about 1: 2 ~ 3, and in crowd, prevalence is 5% ~ 10%, often has genetic background.
During morbidity, have an intense pain, normal hurt like hell, and occur flush, conjunctival congestion, shed tears, watery nasal discharge, nasal obstruction, how not accompany Nausea and vomiting, age of onset often comparatively migraine evening, average 25 years old, the ratio about 4: 1 of men and women.
In migrainous treatment, doctor trained in Western medicine is commonly used the medicine such as pizotifen, amitriptyline to treat, and substantially all has some curative effects, but can only take stopgap measures and can not effect a permanent cure, and the side effect of these medicines is a lot, especially very large to lesions of liver and kidney, just relief of symptoms, cannot play the object of thorough low healing.
Summary of the invention
The object of the present invention, be the deficiency overcoming existing above-mentioned technology, provide one to treat migrainous Chinese medicine composition, this Chinese medicine composition instant effect, therapeutic effect is good, and relapse rate is low, also has sedative action.
For solving the problem, the technical solution adopted in the present invention is:
One treats migrainous Chinese medicine composition, makes the Radix Angelicae Dahuricae 2 grams, Flos Chrysanthemi 3 grams, 2 grams, skin, Spica Prunellae 3 grams, Semen Cassiae 2 grams, Radix Bupleuri 4 grams, 6 grams, Radix Glycyrrhizae, Semen sojae atricolor 3g, Retinervus Luffae Fructus 4g, Bombyx Batryticatus 2g, Succus Momordicae charantiae 3g, Folium Mahoniae 2g, Ink sepiellae seu sepiae 3g, pork liver paste 3g, sheep milk 2g, Succus Momordicae charantiae 10g, Folium Mori 4g and yellow wine 20g by the crude drug of following weight.
Below the further improvement to technique scheme:
After Retinervus Luffae Fructus and Bombyx Batryticatus are pulverized, add Succus Momordicae charantiae and stir, then dryout with after yellow mud parcel, go mud by institute's excess pulverizing; Obtain medicated powder A;
Ink sepiellae seu sepiae is added after being pulverized by Folium Mahoniae; Stir, then add 10g yellow wine, will stir during heat always, prevent burnt, obtain mixture B;
In pork liver paste, add sheep milk, then add Folium Mori; Add 10g yellow wine, be heated to boiling, will stir during heating always, prevent burnt, obtain mixture C;
By the Radix Angelicae Dahuricae 2 grams, Flos Chrysanthemi 3 grams, 2 grams, skin, Spica Prunellae 3 grams, add 500 ml waters and be heated to boiling, then add Semen Cassiae 2 grams, Radix Bupleuri 4 grams, 6 grams, Radix Glycyrrhizae and Semen sojae atricolor 3g, then add 100 ml waters, keep boiling 30 minutes, leach medicinal liquid and obtain medicinal liquid D;
Add in medicinal liquid D and medicated powder A be heated to boiling, obtain medicinal liquid E, until medicinal liquid E be cooled to 50-70 spend time, add mixture B and mixture C stirs, leach medicinal liquid both medicine of the present invention.
As further improvement:
Described pork liver paste is make after whole Hepar Sus domestica is ground into beans shape.
Described Succus Momordicae charantiae is that fresh Fructus Momordicae charantiae is squeezed the juice.
Gained medicine is divided into 3 parts, and point morning, noon and afternoon respectively take portion, and within 2 days, be a course for the treatment of, general 1-2 can fully recover a course for the treatment of, and instant effect, relapse rate is low.
Drug therapy migraine of the present invention, cure rate is high, instant effect, and short treating period also has sedative action.
By above-mentioned contrast, can find out and use treatment by Chinese herbs migraine of the present invention, therapeutic effect is remarkable, and instant effect, cure rate is high, and take medicine 1 day, cure rate reaches more than 92%, and take medicine 5 days, cure rate reaches more than 99%.
Pay a return visit at interval of 2 months the case after curing, without recurrence in 2 years, in 5 years, relapse rate is 0.5%, stable curative effect.
Medicine of the present invention also has the effect of calming the nerves, and in the patient suffering from migraine, have the concurrent insomnia of the case of 85%, after medicine of the present invention of taking medicine, the case of insomnia was all sleeping for that night, and second day energetic, and the present invention calms the nerves Be very effective.
Detailed description of the invention
Embodiment, one treats migrainous Chinese medicine composition, makes the Radix Angelicae Dahuricae 2 grams, Flos Chrysanthemi 3 grams, 2 grams, skin, Spica Prunellae 3 grams, Semen Cassiae 2 grams, Radix Bupleuri 4 grams, 6 grams, Radix Glycyrrhizae, Semen sojae atricolor 3g, Retinervus Luffae Fructus 4g, Bombyx Batryticatus 2g, Succus Momordicae charantiae 3g, Folium Mahoniae 2g, Ink sepiellae seu sepiae 3g, pork liver paste 3g, sheep milk 2g, Succus Momordicae charantiae 10g, Folium Mori 4g and yellow wine 20g by the crude drug of following weight;
After Retinervus Luffae Fructus and Bombyx Batryticatus are pulverized, add Succus Momordicae charantiae and stir, then dryout with after yellow mud parcel, go mud by institute's excess pulverizing; Obtain medicated powder A;
Ink sepiellae seu sepiae is added after being pulverized by Folium Mahoniae; Stir, then add 10g yellow wine, will stir during heat always, prevent burnt, obtain mixture B;
In pork liver paste, add sheep milk, then add Folium Mori; Add 10g yellow wine, be heated to boiling, will stir during heating always, prevent burnt, obtain mixture C;
By the Radix Angelicae Dahuricae 2 grams, Flos Chrysanthemi 3 grams, 2 grams, skin, Spica Prunellae 3 grams, add 500 ml waters and be heated to boiling, then add Semen Cassiae 2 grams, Radix Bupleuri 4 grams, 6 grams, Radix Glycyrrhizae and Semen sojae atricolor 3g, then add 100 ml waters, keep boiling 30 minutes, leach medicinal liquid and obtain medicinal liquid D;
Add in medicinal liquid D and medicated powder A be heated to boiling, obtain medicinal liquid E, until medicinal liquid E be cooled to 50-70 spend time, add mixture B and mixture C stirs, leach medicinal liquid both medicine of the present invention.
Described pork liver paste is make after whole Hepar Sus domestica is ground into beans shape.
Described Succus Momordicae charantiae is that fresh Fructus Momordicae charantiae is squeezed the juice.
Gained medicine is divided into 3 parts, and point morning, noon and afternoon respectively take portion, and within 2 days, be a course for the treatment of, general 1-2 can fully recover a course for the treatment of, instant effect.
For investigating clinical efficacy and the safety of above-described embodiment medicine further, we have selected the treatment curative effect of 386 routine migrainous cases to medicine of the present invention and carry out clinical trial.
Curative effect statistics after taking medicine is as follows:
By above-mentioned contrast, can find out and use treatment by Chinese herbs migraine of the present invention, therapeutic effect is remarkable, and instant effect, cure rate is high, and take medicine 1 day, cure rate reaches more than 92%, and take medicine 5 days, cure rate reaches more than 99%.
Pay a return visit at interval of 2 months the case after curing, without recurrence in 2 years, in 5 years, relapse rate is 0.5%, stable curative effect.
Medicine of the present invention also has the effect of calming the nerves, and in the patient suffering from migraine, have the concurrent insomnia of the case of 85%, after medicine of the present invention of taking medicine, the case of insomnia was all sleeping for that night, and second day energetic, and the present invention calms the nerves Be very effective.
Some patients healing case is as follows:
What certain, female, 14 years old, suffers from migraine, and after taking 2 courses for the treatment of of medicine obtained by the present embodiment, patients symptomatic disappears, recovery from illness.
Korea Spro, female, 29 years old, suffers from migraine, and after taking 1 course for the treatment of of medicine obtained by the present embodiment, patients symptomatic disappears, recovery from illness.
Fourth, man, 43 years old, suffers from migraine, and after taking 2 courses for the treatment of of medicine obtained by the present embodiment, patients symptomatic disappears, recovery from illness.

Claims (4)

1. treat a migrainous Chinese medicine composition, it is characterized in that: make the Radix Angelicae Dahuricae 2 grams, Flos Chrysanthemi 3 grams, 2 grams, skin, Spica Prunellae 3 grams, Semen Cassiae 2 grams, Radix Bupleuri 4 grams, 6 grams, Radix Glycyrrhizae, Semen sojae atricolor 3g, Retinervus Luffae Fructus 4g, Bombyx Batryticatus 2g, Succus Momordicae charantiae 3g, Folium Mahoniae 2g, Ink sepiellae seu sepiae 3g, pork liver paste 3g, sheep milk 2g, Succus Momordicae charantiae 10g, Folium Mori 4g and yellow wine 20g by the crude drug of following weight.
2. one as claimed in claim 1 treats migrainous Chinese medicine composition, it is characterized in that:
After Retinervus Luffae Fructus and Bombyx Batryticatus are pulverized, add Succus Momordicae charantiae and stir, then dryout with after yellow mud parcel, go mud by institute's excess pulverizing; Obtain medicated powder A;
Ink sepiellae seu sepiae is added after being pulverized by Folium Mahoniae; Stir, then add 10g yellow wine, will stir during heat always, prevent burnt, obtain mixture B;
In pork liver paste, add sheep milk, then add Folium Mori; Add 10g yellow wine, be heated to boiling, will stir during heating always, prevent burnt, obtain mixture C;
By the Radix Angelicae Dahuricae 2 grams, Flos Chrysanthemi 3 grams, 2 grams, skin, Spica Prunellae 3 grams, add 500 ml waters and be heated to boiling, then add Semen Cassiae 2 grams, Radix Bupleuri 4 grams, 6 grams, Radix Glycyrrhizae and Semen sojae atricolor 3g, then add 100 ml waters, keep boiling 30 minutes, leach medicinal liquid and obtain medicinal liquid D;
Add in medicinal liquid D and medicated powder A be heated to boiling, obtain medicinal liquid E, until medicinal liquid E be cooled to 50-70 spend time, add mixture B and mixture C stirs, leach medicinal liquid both medicine of the present invention.
3. one as claimed in claim 1 treats migrainous Chinese medicine composition, it is characterized in that: described pork liver paste is make after whole Hepar Sus domestica is ground into beans shape.
4. one as claimed in claim 1 treats migrainous Chinese medicine composition, it is characterized in that: described Succus Momordicae charantiae is that fresh Fructus Momordicae charantiae is squeezed the juice.
CN201510979638.9A 2015-12-24 2015-12-24 Traditional Chinese medicine composition for treating migraine Pending CN105362348A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105920324A (en) * 2016-04-29 2016-09-07 赵逸 Traditional Chinese medicine composition for treating migraine
CN106421173A (en) * 2016-12-27 2017-02-22 山东鲁健生物医药科技有限公司 Health-care food eaten by patient suffered from intractable headache and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491759A (en) * 2015-01-15 2015-04-08 张士红 Traditional Chinese medicine composition for treating cephalagra and preparation method thereof
CN104771599A (en) * 2015-03-16 2015-07-15 张文华 Method utilizing traditional Chinese medicine to treat headache

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491759A (en) * 2015-01-15 2015-04-08 张士红 Traditional Chinese medicine composition for treating cephalagra and preparation method thereof
CN104771599A (en) * 2015-03-16 2015-07-15 张文华 Method utilizing traditional Chinese medicine to treat headache

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
赵龙；等: "偏头痛的临床调治诸法浅探", 《邯郸医学高等专科学校学报》 *
陈绍红；等: "偏头痛的用药规律探讨", 《中华中医药杂志。增刊》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105920324A (en) * 2016-04-29 2016-09-07 赵逸 Traditional Chinese medicine composition for treating migraine
CN106421173A (en) * 2016-12-27 2017-02-22 山东鲁健生物医药科技有限公司 Health-care food eaten by patient suffered from intractable headache and preparation method thereof

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