CN105358160A - 亚硝酸盐的药物制剂及其用途 - Google Patents

亚硝酸盐的药物制剂及其用途 Download PDF

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Publication number
CN105358160A
CN105358160A CN201480022166.1A CN201480022166A CN105358160A CN 105358160 A CN105358160 A CN 105358160A CN 201480022166 A CN201480022166 A CN 201480022166A CN 105358160 A CN105358160 A CN 105358160A
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China
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pain
pharmaceutically acceptable
pharmaceutical composition
study
subjects
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CN201480022166.1A
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English (en)
Chinese (zh)
Inventor
C.克维尔
K.陈
A.索因
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TheraVasc Inc
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TheraVasc Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201480022166.1A 2013-02-20 2014-02-20 亚硝酸盐的药物制剂及其用途 Pending CN105358160A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361767017P 2013-02-20 2013-02-20
US61/767017 2013-02-20
PCT/US2014/017432 WO2014130691A2 (en) 2013-02-20 2014-02-20 Pharmaceutical formulations of nitrite and uses thereof

Publications (1)

Publication Number Publication Date
CN105358160A true CN105358160A (zh) 2016-02-24

Family

ID=51391970

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480022166.1A Pending CN105358160A (zh) 2013-02-20 2014-02-20 亚硝酸盐的药物制剂及其用途

Country Status (12)

Country Link
US (2) US9561249B2 (enExample)
EP (1) EP2958573B1 (enExample)
JP (1) JP2016509030A (enExample)
KR (1) KR102472588B1 (enExample)
CN (1) CN105358160A (enExample)
AU (1) AU2014218916A1 (enExample)
BR (1) BR112015019802A2 (enExample)
CA (1) CA2899602C (enExample)
DK (1) DK2958573T3 (enExample)
ES (1) ES2741146T3 (enExample)
HK (1) HK1218079A1 (enExample)
WO (1) WO2014130691A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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CN108785106A (zh) * 2018-06-05 2018-11-13 中国科学院上海硅酸盐研究所 一种胶状含银磷酸钙纳米复合材料及其制备方法和应用

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US9649334B2 (en) * 2007-11-15 2017-05-16 The Uab Research Foundation Use of nitrite salts in chronic ischemia
BR112015019802A2 (pt) * 2013-02-20 2017-07-18 Theravasc Inc formulações farmacêuticas de nitrito e usos das mesmas
GB201602959D0 (en) 2016-02-19 2016-04-06 Isis Innovation Use of cerebral nitric oxide donors in the assessment of the extent of brain dyfunction following injury
EP3463296A4 (en) * 2016-06-06 2020-02-19 Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Pharmaceutical formulations of nitrite uses thereof
CN111182834B (zh) * 2017-07-14 2025-09-05 国立大学法人大阪大学 利用稀疏建模的疼痛分类和瞬时疼痛的判别
CA3123524C (en) 2019-01-02 2024-01-23 Celagenex Research (India) Pvt. Ltd. Synergistic nutritional compositions for pain management
BR112022008095A2 (pt) * 2019-10-28 2022-07-12 Neuren Pharmaceuticals Ltd Métodos e composições para o tratamento da síndrome de rett

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CN101939014A (zh) * 2007-11-15 2011-01-05 路易斯安那州立大学 亚硝酸盐在慢性缺血中的应用
WO2012052561A2 (en) * 2010-10-21 2012-04-26 Nolabs Ab Topical dermal delivery device for nitric oxide delivery
CN102686111A (zh) * 2009-10-14 2012-09-19 瑟阿瓦斯克有限公司 亚硝酸盐/酯的药物制剂以及其应用

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CN101939014A (zh) * 2007-11-15 2011-01-05 路易斯安那州立大学 亚硝酸盐在慢性缺血中的应用
CN102686111A (zh) * 2009-10-14 2012-09-19 瑟阿瓦斯克有限公司 亚硝酸盐/酯的药物制剂以及其应用
WO2012052561A2 (en) * 2010-10-21 2012-04-26 Nolabs Ab Topical dermal delivery device for nitric oxide delivery

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108785106A (zh) * 2018-06-05 2018-11-13 中国科学院上海硅酸盐研究所 一种胶状含银磷酸钙纳米复合材料及其制备方法和应用

Also Published As

Publication number Publication date
WO2014130691A3 (en) 2014-10-16
US9561249B2 (en) 2017-02-07
WO2014130691A2 (en) 2014-08-28
BR112015019802A2 (pt) 2017-07-18
KR102472588B1 (ko) 2022-12-01
EP2958573B1 (en) 2019-05-08
CA2899602C (en) 2024-01-30
US20150196588A1 (en) 2015-07-16
AU2014218916A1 (en) 2015-09-03
KR20150120479A (ko) 2015-10-27
CA2899602A1 (en) 2014-08-28
HK1218079A1 (zh) 2017-02-03
ES2741146T3 (es) 2020-02-10
US20170143759A1 (en) 2017-05-25
DK2958573T3 (da) 2019-08-05
JP2016509030A (ja) 2016-03-24
EP2958573A4 (en) 2016-10-19
EP2958573A2 (en) 2015-12-30

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