CN105327164A - 一种治疗慢性胰腺炎的中药制剂 - Google Patents

一种治疗慢性胰腺炎的中药制剂 Download PDF

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CN105327164A
CN105327164A CN201510716105.1A CN201510716105A CN105327164A CN 105327164 A CN105327164 A CN 105327164A CN 201510716105 A CN201510716105 A CN 201510716105A CN 105327164 A CN105327164 A CN 105327164A
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周彦彬
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Abstract

本发明公开了一种治疗慢性胰腺炎的中药制剂。此病在中医属于“腹痛”“脾心痛”“泄泻”等范畴。肝脾不调、脾胃虚弱产生湿热、气滞、血瘀、痰浊，以致胰腺出现持久性炎性病变。为此，本发明选择中药地梢瓜、苦竹叶、水皂角、人参果、奶浆参、夜关门、白术、竹叶兰、小二仙草、夏枯草、胡椒、甘草，水煎成汤剂，经临床试验，总有效率达到97.5％，疗效显著。

Description

一种治疗慢性胰腺炎的中药制剂
技术领域
本发明属于中药技术领域，尤其涉及一种治疗慢性胰腺炎的中药制剂。
背景技术
慢性胰腺炎是指由各种不同病因引起的胰腺组织和功能持续性损害，导致胰腺实质和胰管组织的不可逆性损害，并伴有不同程度的胰腺内、外分泌功能障碍，其病理特征为胰腺纤维化。迄今，其发病机制、病理生理和疾病过程仍未明确。常见的西医治疗主要有去除病因、缓解疼痛、改善胰腺的内外分泌功能、内镜或手术治疗等，西医治疗仅限于缓解症状或对其并发症的处理，远期效果不佳。申请人在多年的临床治疗实践中，利用中药治疗此病，取得了较好的疗效，较好地缓解患者症状，副作用小，并能有效地改善预后。
发明内容
本发明的目的是提供一种治疗慢性胰腺炎的中药制剂。此病在中医属于“腹痛”“脾心痛”“泄泻”“癥瘕积聚”等范畴。肝脾不调、脾胃虚弱产生湿热、气滞、血瘀、痰浊，以致胰腺出现持久性炎性病变。
本发明的目的是通过以下技术方案实现的，该治疗慢性胰腺炎的中药制剂由以下重量份的中药制成：地梢瓜5-10份、苦竹叶6-12份、水皂角6-10份、人参果8-15份、奶浆参7-11份、夜关门7-11份、白术5-10份、竹叶兰5-10份、小二仙草6-11份、夏枯草6-11份、胡椒7-13份、甘草8-15份。
优选的：地梢瓜7份、苦竹叶9份、水皂角9份、人参果12份、奶浆参9份、夜关门9份、白术7份、竹叶兰7份、小二仙草8份、夏枯草8份、胡椒10份、甘草12份。
制备方法：按传统方法制成汤剂。
方中：地梢瓜补肺气、清热降火、生津止渴、消炎止痛；苦竹叶清热利窍解毒；水皂角清肝明目、和脾利水；人参果强心补肾、生津止渴、补脾健胃、调经活血；奶浆参补肝肾、益脾；夜关门补肝肾、益肺阴、散瘀消肿；白术补脾益胃、和中燥湿；竹叶兰补肺、健脾、益肾；小二仙草清热通便、活血解毒；夏枯草清肝、散结；胡椒温中下气、消痰解毒；甘草和中缓急、润肺解毒，调和诸药。
临床资料
1.一般资料选择2009-2010年在本院门诊和住院就诊的慢性胰腺炎80例，其中男性40例，女性40例，确诊时年龄为18-69岁，平均41岁，自症状出现至确诊病程为5d～5年，平均28个月。
2.诊断标准参照中华医学会消化病学分会制定的诊断标准：(1)典型的临床表现(腹痛、胰腺外分泌功能不全等)；(2)病理学诊断明确；(3)影像学检查提示胰腺实质及胰管等改变(X线、B超、CT或ERCP发现胰腺钙化、结石、胰管扩张或符合慢性胰腺炎改变)；(4)实验室检查提示胰腺外分泌功能不全的依据。
3.治疗方法患者服用本发明所述中药制剂，称取地梢瓜7克、苦竹叶9克、水皂角9克、人参果12克、奶浆参9克、夜关门9克、白术7克、竹叶兰7克、小二仙草8克、夏枯草8克、胡椒10克、甘草12克，水煎成汤剂，每日一剂，分早、晚2次服用，七日为一个疗程，连续治疗3个疗程。
4.疗效标准治愈：症状、体征消失。好转：症状、体征好转。未愈：症状、体征无变化或趋于严重。
5.治疗结果80例患者治疗3个疗程后观察疗效，其中治愈18例(22.5％)，好转60例(75.0％)，未愈2例(2.5％)，总有效率97.5％。在整个治疗过程中，患者未出现明显的不良反应，血、尿、大便常规、心电图及肝、肾功能均无明显变化。
具体实施方式
实施方式一：称取地梢瓜7克、苦竹叶9克、水皂角9克、人参果12克、奶浆参9克、夜关门9克、白术7克、竹叶兰7克、小二仙草8克、夏枯草8克、胡椒10克、甘草12克，水煎成汤剂。
实施方式二：称取地梢瓜5克、苦竹叶12克、水皂角6克、人参果15克、奶浆参7克、夜关门7克、白术10克、竹叶兰5克、小二仙草11克、夏枯草6克、胡椒13克、甘草8克，水煎成汤剂。
实施方式三：称取地梢瓜10克、苦竹叶6克、水皂角10克、人参果8克、奶浆参11克、夜关门11克、白术5克、竹叶兰10克、小二仙草6克、夏枯草11克、胡椒7克、甘草15克，水煎成汤剂。

Claims (2)

1.一种治疗慢性胰腺炎的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：地梢瓜5-10份、苦竹叶6-12份、水皂角6-10份、人参果8-15份、奶浆参7-11份、夜关门7-11份、白术5-10份、竹叶兰5-10份、小二仙草6-11份、夏枯草6-11份、胡椒7-13份、甘草8-15份。
2.如权利要求1所述的一种治疗慢性胰腺炎的中药制剂，其特征在于该中药制剂由以下重量份的中药制成：优选的：地梢瓜7份、苦竹叶9份、水皂角9份、人参果12份、奶浆参9份、夜关门9份、白术7份、竹叶兰7份、小二仙草8份、夏枯草8份、胡椒10份、甘草12份。
CN201510716105.1A 2015-10-21 2015-10-21 一种治疗慢性胰腺炎的中药制剂 Pending CN105327164A (zh)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101480478A (zh) * 2008-12-19 2009-07-15 重庆市合川区生产力促进中心 治疗慢性胰腺炎的中药组合物
CN103977300A (zh) * 2014-05-15 2014-08-13 南京中医药大学 一种具有治疗胰腺炎的中药复方组合物及其应用
CN104721745A (zh) * 2015-03-25 2015-06-24 曹嘉明 一种治疗慢性胰腺炎的中药组合物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101480478A (zh) * 2008-12-19 2009-07-15 重庆市合川区生产力促进中心 治疗慢性胰腺炎的中药组合物
CN103977300A (zh) * 2014-05-15 2014-08-13 南京中医药大学 一种具有治疗胰腺炎的中药复方组合物及其应用
CN104721745A (zh) * 2015-03-25 2015-06-24 曹嘉明 一种治疗慢性胰腺炎的中药组合物

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