CN105288162A - Traditional Chinese medicine preparation for inhibiting herpes virus - Google Patents
Traditional Chinese medicine preparation for inhibiting herpes virus Download PDFInfo
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- CN105288162A CN105288162A CN201510844631.6A CN201510844631A CN105288162A CN 105288162 A CN105288162 A CN 105288162A CN 201510844631 A CN201510844631 A CN 201510844631A CN 105288162 A CN105288162 A CN 105288162A
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Abstract
The invention discloses a traditional Chinese medicine preparation for inhibiting herpes virus. The traditional Chinese medicine preparation has the active ingredients prepared from the following raw materials: flos lonicerae, rhizoma belamcandae, rhizoma polygoni cuspidati, herba portulacae, radix paeoniae rubra, rhizoma polygonati, cacumen biotae, astragalus, spica prunellae, radix et rhizoma rhei, herba pyrrosiae, radix trichosanthis, radix achyranthis bidentatae, fructus xanthii, radix panacis quinquefolii and girald pteroxygonum root. The traditional Chinese medicine is convenient to use, good in adsorption effect and free from adverse and toxic or/and side effects, and clinical tests show that the traditional Chinese medicine preparation has an extremely good relief and treatment effect on herpes simplex, and is suitable for being popularized and applied to clinical treatment and nursing of herpes simplex.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relating to a kind of for suppressing the Chinese medicine preparation of herpesvirus.
Background technology
Virus infected herpes (HerpesSimplex) is a kind of by the virogenetic viral dermatosis of virus infected herpes.Divide herpes simplex and herpes zoster, herpes simplex (herpessimplex) is the dermatosis caused by a kind of herpes simplex virus, invade well in mucocutaneous intersection, show as limitation bunch collection property phlycten, herpes zoster (herpeszoster) is then caused by herpesvirus, along intensive phlysis and the neuralgia of side peripheral nerve zonal distribution, regional nodes's enlargement is the acute viral dermatosis of principal character.
People is the unique born host of virus infected herpes.Virus through breathing, oral cavity, genital mucosa and broken skin enters in body, dive to occupy human body health and happiness mucosa, blood, saliva and learn and learn in ganglionic cell.Primary infection mostly is recessive, and mostly obviously show without clinical symptoms or in subclinical, only a guy can appear clinical symptoms in one's mind.After primary infection occurs, virus can be hidden in body for a long time.The carrier that more than 50% is this virus is about had in healthy population.HSV does not produce prolonged immunity in human body, when body matches power depreciation, as heating, the disorder of gastrointestinal effect, menstruation, gestation, focal infection and motivation break an agreement time, the HSV of concealment is activated and falls ill in body.
For the treatment of virus infected herpes, also have a lot of problem not solve at present, treatment thoroughly can't remove virus, stops disease palindromia.Current treatment divides general treatment, antiviral therapy and traditional Chinese medical herbal treatment.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of for suppressing the Chinese medicine preparation of herpesvirus, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, there are fabulous alleviation and therapeutic effect to virus infected herpes, are suitable for virus infected herpes clinical treatment and nursing is applied.
For solving the problems of the technologies described above, provided by the invention a kind of for suppressing the Chinese medicine preparation of herpesvirus, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Preferably, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Preferably, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Preferably, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
For suppressing a preparation method for the Chinese medicine preparation of herpesvirus, comprise following processing step:
Step 1: get Radix Panacis Quinquefolii, Radix Polygoni Ciliinerve and Radix Achyranthis Bidentatae paper decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 130 order fine powders, for subsequent use;
Step 2: Flos Lonicerae, Cacumen Platycladi, Spica Prunellae, Herba Portulacae and Folium Pyrrosiae are mashed strand juice, filters, stays juice for subsequent use;
Step 3: Rhizoma Belamcandae, Rhizoma Polygonati, Radix Et Rhizoma Rhei, Radix Trichosanthis and Fructus Xanthii are put decontamination, is placed in container, adds the distilled water of 7 ~ 9 times amount, soaks after 2 ~ 3 hours, boils 3 ~ 4 hours, extracts; Again add 5 ~ 7 times amount distilled water, boil 1 ~ 3 hour, extract; Finally, add 3 ~ 5 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
Step 4, get Rhizoma Polygoni Cuspidati, Radix Paeoniae Rubra and the Radix Astragali remove impurity, mix thoroughly vexed with vinegar water, the micro-stir-fry of slow fire, taking-up is dried, and is placed in mortar and grinds into powder, cross 160 order fine powders, for subsequent use;
Step 5: the fine powder obtained by above-mentioned steps 1, step 4, the juice obtained by step 2 and the filtrate obtained by step 3 are stirred, make tablet, is the described Chinese medicine preparation for suppressing herpesvirus.
The property of medicine of the present invention's Chinese medicine used is as follows:
Flos Lonicerae: Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Rhizoma Belamcandae: bitter in the mouth, cold in nature, micro-poison.Energy heat-clearing and toxic substances removing, eliminating stagnation antiinflammatory, reducing swelling and alleviating pain, relieving cough and resolving phlegm; " the SHENGCAO property of medicine standby will " carries: " applying skin ulcer washes swollen, and Herba Sidae Szechuensis blood, traumatic injury is also used.”
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature, returns liver, gallbladder, lung meridian.For jaundice due to damp-heat, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, burn due to hot liquid or fire, amenorrhea, lump in the abdomen, instep plays damage, cough due to lung-heat." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: attack all toxic swellings, only have sore throat, diuresis, walk meridians.Control five types of stranguria nebulousurine, anal fistula, carbuncle sore, married woman's leucorrhea with red and white discharge.
Herba Portulacae, cold in nature, sweet in the mouth acid; Enter the heart, liver, spleen, large intestine channel.Heat-clearing and toxic substances removing, loose blood detumescence.Control hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, trace scrofula.) Tang Materia Medica carries: main all swollen fistula verruca, smash and wipe it; The main regurgitation of drink juice, Zhu Lin, incised wound blood flow, removing blood stasis addiction disease addiction, children's You Liang; Wash tight lip, pimples, horse antiperspirant with juice, penetrate being recovered of work poison painting.
Radix Paeoniae Rubra: bitter in the mouth, cold nature, returns Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Shennong's Herbal carries: " Radix Paeoniae, bitter in the mouth is put down.Main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending cold and heat hernia abdominal mass, pain relieving ... raw Semen Coicis.”
Rhizoma Polygonati: property is put down, and sweet in the mouth, enters spleen, lung, kidney channel.Nourishing YIN and moistening the lung; Invigorating the spleen and replenishing QI, Zishen fill fine.Main deficiency of YIN chronic cough; Xeropulmonary cough; Insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; Tinnitus order is dark; Early whitening of beard and hair; Body void is won thin; Wind favus disease.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst." detailed outline " carries: mend all void, only cold and heat, replenishing essence marrow, lower three corpse worms.
Cacumen Platycladi, bitter in the mouth, puckery, cold.Return lung, liver, spleen channel.For spitting blood, epistaxis, spitting of blood, has blood in stool, metrostaxis, cough due to lung-heat, heat in blood alopecia, early whitening of beard and hair." Bencao Congxin " carries: purify the blood most point damp and hot.Emesis nosebleed collapses pouring.Hemorrhoidal hamorrhage hematuria.Dysentery.All blood disorders.
The Radix Astragali: the Radix Astragali, has another name called continuous stilbene.The sweet temperature of property, returns lung meridian, has tonifying Qi and lifting yang, function that benefit defends consolidating superficial resistance.Modern medicine study shows, the Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Spica Prunellae: acrid in the mouth, hardship, cold.Return liver, gallbladder meridian.Clearing away heat-fire, improving eyesight, mass dissipating and swelling eliminating.Shennong's Herbal carries: " main cold and heat, scrofula, scrofula, head sore, broken disease.Loose wart stagnation of QI, swelling of the feet arthralgia chiefly caused by damp pathogen.”
Radix Et Rhizoma Rhei: bitter in the mouth, cold.Enter spleen, stomach, large intestine, pericardium, Liver Channel.For stasis removing, purging fire and cooling blood, clots absorbing stimulates the menstrual flow." national Chinese herbal medicine compilation " carries: removing the relative excess heat, removing mass is stagnant, clots absorbing blood.Cure mainly: excess-heat constipation, food stagnation is stagnated, stomachache, acute appendicitis, acute infectious hepatitis, blood stasis amenorrhea, toothache, epistaxis, acute conjunctivitis; Burn and scald is controlled in external, suppurative dermatosis, carbuncle skin infection.
Folium Pyrrosiae: bitter but sweet flavor, cool, enter lung, urinary bladder channel.Cure mainly: relieving stranguria by diuresis, lung heat clearing expels the heat-evil.Control and drench pain, hematuria, lithangiuria, nephritis, metrorrhagia, dysentery, cough due to lung-heat, chronic tracheitis, incised wound, carbuncle." detailed outline " carries: main metrorrhagia, incised wound, lung heat clearing gas.
Radix Trichosanthis: sweet in the mouth, micro-hardship, be slightly cold, attach to the lung and stomach meridians.Cure mainly: calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin." book on Chinese herbal medicine converge with speech " carries: " Radix Trichosanthis, it is hot and suffocating to move back the five internal organs, and as heart-fire is contained and dry tongue and mouth, lung-fire is contained and pharyngeal swelling sore throat, and spleen-fire is contained and dispute tooth swells, and phlegm-fire is contained and cough is not peaceful.If the side of body of liver-fire is swollen migratory arthralgia caused by wind, the hectic fever due to YIN-deficiency dysphoria with smothery sensation of kidney fire, or carbuncle is not burst, and pyretic toxicity does not fall apart, or five types of jaundice yellow skin and eye, and if if little water drenches puckery, be caused by all burning hot pent-up, phlegm-fire, falls in only this agent energy relieving stagnation, and can control it.Its property is sweet cold again, kindly can control thirsty, and control empty thirsty from tonic, control fire from the medicine of a cold nature thirsty, control yearningly strongly fragrant from gas medicine, controlling excessive thirst from blood medicine, is control thirsty key medicine also.”
Radix Achyranthis Bidentatae: " Yunnan Chinese herbal medicine ": " sweet micro-acid, cool." enter the heart, liver, large intestine three warp.Cure mainly: promoting blood circulation to remove blood stasis, damp eliminating diuresis, heat-clearing and toxic substances removing.Control gonorrhea, hematuria, women's amenorrhea, lump in the abdomen, rheumatic arthritis, beriberi, edema, dysentery, malaria, diphtheria, carbuncle, traumatic injury." south of the Five Ridges gather medicinal herbs record " carries: be astringency and diuresis medicine, purify the blood sterilization.Control larynx disease and smash juice rinsing the mouth; Loose blood and relieving pain again, reason beriberi, decocts wine clothes.
Fructus Xanthii: bitter in the mouth, sweet, pungent, warm in nature.Return lung, Liver Channel.For anemofrigid cold, nasal sinusitis, rheumatic arthralgia, the cards such as rubella pruritus.Shennong's Herbal is recorded: " Fructus Xanthii, cure mainly the cold pain of public attention, rheumatism general arthralgia, extremity arrest goldenrain tree pain, and dislike the dead flesh of meat, gonalgia, takes QI invigorating for a long time.”
Radix Panacis Quinquefolii: Radix Panacis Quinquefolii is cold in nature, bitter in the mouth, micro-sweet, GUIXIN, lung, kidney channel, have effect of tonifying the lung pathogenic fire reducing, nourishing the stomach to promote the production of body fluid.Radix Panacis Quinquefolii is as the first-selected medical material of qi-tonifying health-care, and can promote that serum albumin synthesizes, bone marrow protein synthesizes, organ protein synthesizes, improve immunity of organisms, anticancer grows, and effectively resists cancer.Long take that Radix Panacis Quinquefolii can reduce blood coagulability, suppresses platelet aggregation, atherosclerosis promote Growth of red blood cells, increase hematochrome.
Radix Polygoni Ciliinerve: sour in the mouth, hardship, puckery, cool.Cure mainly: heat clearing away, removing toxic substances, hemostasis, pain relieving.For enteritis, dysentery, lumbago and skelalgia, has blood in stool, metrorrhagia; Burn and scald is controlled in external, furuncle, lyssodexis.
The present invention compared with prior art, there is following beneficial effect: selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine theory, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, there are fabulous alleviation and therapeutic effect to virus infected herpes, are suitable for virus infected herpes clinical treatment and nursing is applied.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The processing step of Chinese medicine preparation preparation method of the present invention is:
Step 1: get Radix Panacis Quinquefolii, Radix Polygoni Ciliinerve and Radix Achyranthis Bidentatae paper decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 130 order fine powders, for subsequent use;
Step 2: Flos Lonicerae, Cacumen Platycladi, Spica Prunellae, Herba Portulacae and Folium Pyrrosiae are mashed strand juice, filters, stays juice for subsequent use;
Step 3: Rhizoma Belamcandae, Rhizoma Polygonati, Radix Et Rhizoma Rhei, Radix Trichosanthis and Fructus Xanthii are put decontamination, is placed in container, adds the distilled water of 7 ~ 9 times amount, soaks after 2 ~ 3 hours, boils 3 ~ 4 hours, extracts; Again add 5 ~ 7 times amount distilled water, boil 1 ~ 3 hour, extract; Finally, add 3 ~ 5 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
Step 4, get Rhizoma Polygoni Cuspidati, Radix Paeoniae Rubra and the Radix Astragali remove impurity, mix thoroughly vexed with vinegar water, the micro-stir-fry of slow fire, taking-up is dried, and is placed in mortar and grinds into powder, cross 160 order fine powders, for subsequent use;
Step 5: the fine powder obtained by above-mentioned steps 1, step 4, the juice obtained by step 2 and the filtrate obtained by step 3 are stirred, make tablet, is the described Chinese medicine preparation for suppressing herpesvirus.
Usage and dosage: oral, every day 3 times, each 2, within 5 days, be a course for the treatment of, 5 ~ 6 courses for the treatment of can take effect, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
Select the routine clinical observation of virus infected herpes patient 100 of making a definite diagnosis, patient is divided into two groups at random, treatment group 50 example, 20 ~ 58 years old age, 35 years old mean age, the course of disease 2 months ~ 1 year, average 8 months.Matched group 50 example, 23 ~ 54 years old age, 38 years old mean age, the course of disease 1 month ~ 1 year, average 7.5 months; The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection
Treatment group patient takes medicine of the present invention, oral, warm water delivery service in half an hour after meal, every day 3 times, each 2, within 5 days, is a course for the treatment of, takes 4 ~ 6 courses for the treatment of continuously, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes tablets of vacyclovir, oral, every day 3 times, each 2.
3, efficacy determination:
Effective: the skin bleb state of an illness is obviously alleviated, immunity strengthens, and picks body.
Invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, effective 48 examples, invalid 2 examples, total effective rate 96%.
Effective 38 examples in matched group, invalid 12 routine total effective rates 76%.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Above by specific embodiment to invention has been detailed description, but these are not construed as limiting the invention.Without departing from the principles of the present invention, those skilled in the art also can make many distortion and improvement, and these also should be considered as protection scope of the present invention.
Claims (5)
1. for suppressing a Chinese medicine preparation for herpesvirus, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
2. according to claim 1 a kind of for suppressing the Chinese medicine preparation of herpesvirus, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
3. according to claim 1 a kind of for suppressing the Chinese medicine preparation of herpesvirus, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
4. according to claim 1 a kind of for suppressing the Chinese medicine preparation of herpesvirus, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
5. a kind of for suppressing the preparation method of the Chinese medicine preparation of herpesvirus as described in claim 1-4, it is characterized in that: comprise following processing step:
Step 1: get Radix Panacis Quinquefolii, Radix Polygoni Ciliinerve and Radix Achyranthis Bidentatae paper decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 130 order fine powders, for subsequent use;
Step 2: Flos Lonicerae, Cacumen Platycladi, Spica Prunellae, Herba Portulacae and Folium Pyrrosiae are mashed strand juice, filters, stays juice for subsequent use;
Step 3: Rhizoma Belamcandae, Rhizoma Polygonati, Radix Et Rhizoma Rhei, Radix Trichosanthis and Fructus Xanthii are put decontamination, is placed in container, adds the distilled water of 7 ~ 9 times amount, soaks after 2 ~ 3 hours, boils 3 ~ 4 hours, extracts; Again add 5 ~ 7 times amount distilled water, boil 1 ~ 3 hour, extract; Finally, add 3 ~ 5 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
Step 4, get Rhizoma Polygoni Cuspidati, Radix Paeoniae Rubra and the Radix Astragali remove impurity, mix thoroughly vexed with vinegar water, the micro-stir-fry of slow fire, taking-up is dried, and is placed in mortar and grinds into powder, cross 160 order fine powders, for subsequent use;
Step 5: the fine powder obtained by above-mentioned steps 1, step 4, the juice obtained by step 2 and the filtrate obtained by step 3 are stirred, make tablet, is the described Chinese medicine preparation for suppressing herpesvirus.
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| CN104042761A (en) * | 2014-07-05 | 2014-09-17 | 朱克兰 | Traditional Chinese medicine (TCM) composition for treating herpes zoster |
| CN104758600A (en) * | 2015-03-23 | 2015-07-08 | 张吉宏 | Pharmaceutical composition for treating herpes simplex virus |
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2015
- 2015-11-27 CN CN201510844631.6A patent/CN105288162A/en active Pending
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| CN1105589A (en) * | 1994-09-21 | 1995-07-26 | 复旦大学 | Broad-spectrum antibacterial antiviral traditional Chinese medicine and its preparation method |
| CN102342990A (en) * | 2011-09-28 | 2012-02-08 | 李军 | Chinese medicinal composition for treating herpes zoster |
| CN104042761A (en) * | 2014-07-05 | 2014-09-17 | 朱克兰 | Traditional Chinese medicine (TCM) composition for treating herpes zoster |
| CN104758600A (en) * | 2015-03-23 | 2015-07-08 | 张吉宏 | Pharmaceutical composition for treating herpes simplex virus |
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