CN105267760A - Medicine for treating migraine - Google Patents
Medicine for treating migraine Download PDFInfo
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- CN105267760A CN105267760A CN201510867879.4A CN201510867879A CN105267760A CN 105267760 A CN105267760 A CN 105267760A CN 201510867879 A CN201510867879 A CN 201510867879A CN 105267760 A CN105267760 A CN 105267760A
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Abstract
The invention discloses a medicine for treating migraine. The medicine is prepared from the following components by virtue of scientific and reasonable compatibility according to the principles of monarch, minister, assistant and guide drugs: herba conyzae, folium apocyni veneti, wild buckwheat, divaricate saposhnikovia root, arisaema cum bile, semen cassiae, polygala tenuifolia, ligusticum wallichii, pipewort, radix angelicae, tree falsespiraea bark, Dicliptera chinensis, Rumex crispus, rice sprouts, anisochilus, sargent craneberrybuch branchlet and leaf, root of Lindera angustifolia, przewalsk St. Johnwort herb, fleshfingered citron flower, Senecio campestris DC., Picria fel-terrae, Peking Euphorbia Root, potentilla chinensis, inula herb, azedarach, radix tinosporae, uncaria, turpentine, swertia mileensis, quassia, Cacumen biotae, radix bupleuri, patrinia, frankincense, motherwort fruit, pseudo-ginseng, gastrodia elata, fructus viticis, Cinnamomum appelianum Schewe, earthworm, elecampane, tremella and the like. The medicine has the effects of reconciling superficies and interior, soothing liver-qi stagnation, regulating the flow of vital energy and relieving middle-Jiao, removing dampness and benefiting dryness, regulating the middle warmer and tonifying qi, calming endogenous wind and arresting convulsion and calming the heart and soothing the nerves and has an obvious effect on clinical treatment of migraine caused by wind-evil intruding the brain, blood stasis obstructing the collaterals, insufficiency of blood and essence and the like.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly relate to one and be used for the treatment of migrainous medicine.
Background technology
Migraine is clinical modal primary headache type; clinical with ictal middle severe, sample of beating headache for main manifestations; headache mostly is inclined side; general lasting 4 hours ~ 72 hours; can with Nausea and vomiting; light, Sound stimulat or daily routines all can increase the weight of headache, and quiet environment, rest can alleviate headache.Migraine is a kind of common chronic forms vascular illness, and a lot of disease is in child and adolescence, and the young and middle-aged phase reaches onset peak, and women is common, and men and women's Proportion of patients is about 1: 2 ~ 3, and in crowd, prevalence is 5% ~ 10%, often has genetic background.Because migraine formation mechenism is very complicated, prior art generally adopts western medicine to relieve the pain treatment to migrainous treatment, and long-term taking Western medicine easily makes patient form drug dependence.
Summary of the invention
In view of above-mentioned the deficiencies in the prior art, the one that the object of the present invention is to provide is used for the treatment of migrainous medicine.
For solving the problems of the technologies described above, technical solution of the present invention comprises:
One is used for the treatment of migrainous medicine, and according to weight portion, it comprises following component:
Conyza blinii 5 parts-20 parts, Folium Apocyni Veneti 5 parts-20 parts, Rhizoma Fagopyri Dibotryis 4 parts-15 parts, Radix Saposhnikoviae 1 part-12 parts, Arisaema Cum Bile 5 parts-18 parts, Semen Cassiae 5 parts-15 parts, Radix Polygalae 1 part-13 parts, Rhizoma Chuanxiong 1 part-10 parts, Flos Eriocauli 3 parts-14 parts, the Radix Angelicae Dahuricae 5 parts-15 parts, Cortex Sorbariae Arboreae 3 parts-18 parts, Herba Diclipterae Chinensis 5 parts-17 parts, Radix Rumicis Crispi 1 part-10 parts, Fructus Setariae Germinatus 5 parts-12 parts, Herba lysimachiae capillipedis 3 parts-14 parts, Folium et Cacumen Viburni Sargentii 5 parts-15 parts, Lindera angustifolia Cheng 1 part-12 parts, Hypericum przewalskii Maxim. 5 parts-20 parts, Flos Citri Sarcodactylis 5 parts-20 parts, Herba Senecionis Kirilowi 5 parts-20 parts, Radix Picriae felterrae 5 parts-20 parts, 5 parts-20 parts, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis 5 parts-20 parts, Herba Inulae 1 part-13 parts, Cortex Meliae 1 part-12 parts, Radix Tinosporae 1 part-12 parts, Ramulus Uncariae Cum Uncis 1 part-12 parts, Oleum Terebinthinae 15 parts-32 parts, Herba Swertiae Mileensis 5 parts of-20 parts of parts, Ramulus Et Folium Picrasmae 5 parts-15 parts, Cacumen Platycladi 1 part-10 parts, Radix Bupleuri 5 parts-20 parts, Herba Patriniae 5 parts-15 parts, Olibanum 1 part-13 parts, Fructus Leonuri 1 part-12 parts, Radix Notoginseng 1 part-8 parts, 1 part-8 parts, Rhizoma Gastrodiae, Fructus Viticis 1 part-10 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin 1 part-10 parts, Pheretima 1 part-8 parts, the Radix Aucklandiae 1 part-13 parts and 5 parts-15 parts, Tremella.
Described medicine, wherein, according to weight portion, it comprises following component
Conyza blinii 15 parts, Folium Apocyni Veneti 11 parts, Rhizoma Fagopyri Dibotryis 10 parts, Radix Saposhnikoviae 5 parts, Arisaema Cum Bile 11 parts, Semen Cassiae 10 parts, Radix Polygalae 8 parts, Rhizoma Chuanxiong 5 parts, Flos Eriocauli 8 parts, the Radix Angelicae Dahuricae 10 parts, Cortex Sorbariae Arboreae 8 parts, Herba Diclipterae Chinensis 10 parts, Radix Rumicis Crispi 5 parts, Fructus Setariae Germinatus 8 parts, Herba lysimachiae capillipedis 7 parts, Folium et Cacumen Viburni Sargentii 10 parts, Lindera angustifolia Cheng 8 parts, Hypericum przewalskii Maxim. 10 parts, Flos Citri Sarcodactylis 10 parts, Herba Senecionis Kirilowi 10 parts, Radix Picriae felterrae 10 parts, 10 parts, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis 12 parts, Herba Inulae 5 parts, Cortex Meliae 7 parts, Radix Tinosporae 5 parts, Ramulus Uncariae Cum Uncis 5 parts, Oleum Terebinthinae 20 parts, Herba Swertiae Mileensis 15 parts, Ramulus Et Folium Picrasmae 10 parts, Cacumen Platycladi 5 parts, Radix Bupleuri 15 parts, Herba Patriniae 11 parts, Olibanum 3 parts, Fructus Leonuri 6 parts, Radix Notoginseng 3 parts, 2 parts, Rhizoma Gastrodiae, Fructus Viticis 5 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin 5 parts, Pheretima 3 parts, the Radix Aucklandiae 6 parts and 10 parts, Tremella.
One provided by the invention is used for the treatment of migrainous medicine, by conyza blinii, Folium Apocyni Veneti, Rhizoma Fagopyri Dibotryis, Radix Saposhnikoviae, Arisaema Cum Bile, Semen Cassiae, Radix Polygalae, Rhizoma Chuanxiong, Flos Eriocauli, the Radix Angelicae Dahuricae, Cortex Sorbariae Arboreae, Herba Diclipterae Chinensis, Radix Rumicis Crispi, Fructus Setariae Germinatus, Herba lysimachiae capillipedis, Folium et Cacumen Viburni Sargentii, Lindera angustifolia Cheng, Hypericum przewalskii Maxim., Flos Citri Sarcodactylis, Herba Senecionis Kirilowi, Radix Picriae felterrae, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis, Herba Inulae, Cortex Meliae, Radix Tinosporae, Ramulus Uncariae Cum Uncis, Oleum Terebinthinae, Herba Swertiae Mileensis, Ramulus Et Folium Picrasmae, Cacumen Platycladi, Radix Bupleuri, Herba Patriniae, Olibanum, Fructus Leonuri, Radix Notoginseng, Rhizoma Gastrodiae, Fructus Viticis, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin, Pheretima, the Radix Aucklandiae, with multi-flavor medicines such as Tremella, principle according to " monarch " carries out scientific and reasonable compatibility, reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, dehumidifying benefit is dry, with middle QI invigorating, dispelling wind and relieving convulsion, mind tranquilizing and the heart calming, brain is entered to by ailment said due to cold or exposure, obstruction of collaterals by blood stasis, the migraine clinical therapeutic efficacy that asthenia of essence and blood etc. cause is remarkable.Its pharmacology is specific as follows:
Conyza blinii: nature and flavor are bitter, cold.Function cures mainly: heat clearing and inflammation relieving, eliminating fire and detoxication.For acute icterohepatitis, toothache, chronic tracheitis, stomatitis, pharyngolaryngitis, tonsillitis, nephritis, malaria; Eye conjunctivitis is controlled in external, otitis media, skin infection, eczema, traumatic hemorrhage.
Folium Apocyni Veneti: function cures mainly: suppressing the hyperactive liver is calmed the nerves, clearing away heat and promoting diuresis.For dizziness due to hyperactivity of liver-YANG, palpitation and insomnia, edema oliguria; Hypertension, neurasthenia, nephritis edema.
Rhizoma Fagopyri Dibotryis: function cures mainly: heat-clearing and toxic substances removing; To invigorate blood circulation eliminating carbuncle; Expelling wind and removing dampness sore; Snake bite and insect sting.Be used for the treatment of lung abscess; Lung-heat cough with asthma; Laryngopharynx swelling and pain; Dysentery; Rheumatism arthromyodynia; Traumatic injury; Carbuncle cancer.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature.Gui Jing returns bladder, lung, spleen, Liver Channel.Effect expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.Cure mainly for diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus just, insufficiency of the spleen leading to overabundance of dampness.
Arisaema Cum Bile: nature and flavor bitter cold, micro-pungent, cool.Function cures mainly: clearing away fire and eliminating phlegm, relieving convulsion fixed chronic.Control middle wind-phlegm fan, infantile convulsion epilepsy, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo.
Semen Cassiae: cold nature; Sweet, bitter, salty; Function cures mainly: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.The headache caused excessive rising of liver-YANG, dizziness, insomnia, cerebral arteriosclerosis, cervical spondylosis etc., all have assosting effect.
Radix Polygalae: warm in nature; Bitter, pungent; Function cures mainly: Fructus Alpiniae Oxyphyllae of calming the nerves, and eliminates the phlegm, detumescence.The insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.Clinically, Radix Polygalae have calmness, hypnosis, convulsion and eliminate the phlegm, antitussive, hypotensive effect.
Rhizoma Chuanxiong: warm in nature; Pungent; Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, stomachache, costa sternales twinge, tumbling and swelling, headache, rheumatic arthralgia.
Flos Eriocauli: property is put down; Pungent, sweet; Function cures mainly: dispelling wind and heat pathogens, improving eyesight, nebula removing.For wind heat conjunctival congestion, swell and ache photophobia, nebula of looking unfamiliar film, headache due to pathogenic wind-heat.
The Radix Angelicae Dahuricae: warm in nature; Pungent; Function cures mainly: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea.
Cortex Sorbariae Arboreae: nature and flavor are bitter; Cold.Function cures mainly: blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Main traumatic injury, fracture, rheumatic arthralgia.
Herba Diclipterae Chinensis: nature and flavor are sweet; Micro-hardship; Function cures mainly: heat clearing away; Removing heat from blood; Dampness removing; Removing toxic substances.Main cold, fever; Calentura sends out speckle; Tell epistaxis; Have blood in stool; Hematuria; Metrorrhagia; Cough due to lung-heat; Laryngopharynx swelling and pain; Liver-heat conjunctival congestion; Infantile convulsion; Dribbling urination; Leukorrhagia; Herpes zoster; Carbuncle furuncle furuncle; Serpentis lyssodexis.
Radix Rumicis Crispi: nature and flavor are bitter; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Cooling blood for hemostasis; Relieving constipation parasite killing.Main acute, chronic hepatitis; Intestinal is scorching; Dysentery; Chronic tracheitis; Spit blood; Epistaxis; Have blood in stool; Metrorrhagia; Constipation with heat retention; Swollen ulcer drug; Scabies; Tinea alba.
Fructus Setariae Germinatus: nature and flavor are sweet; Flat.Function cures mainly: promoting digestion and removing stagnation; Spleen benefiting and stimulating the appetite.Main meal products shop is long-pending stagnates; Distension is had loose bowels; Insufficiency of the spleen few food; Beriberi edema.
Herba lysimachiae capillipedis: nature and flavor are pungent; Warm in nature.Function cures mainly: removing dampness keeps away turbid; Inducing diuresis to remove edema.Main summer-heat is aobvious vomits and diarrhoea; Edema; Dysuria.
Folium et Cacumen Viburni Sargentii: nature and flavor are sweet; Bitter; Property is put down.Function cures mainly: dredge the meridian passage; Detoxifying and relieving itching.Main lumbago and skelalgia; Lumbar sprain and QI divergeny; Furuncle; Scabies; Skin pruritus.
Lindera angustifolia Cheng: nature and flavor are pungent; Temperature.Function cures mainly: dispel the wind; Dehumidifying; Circulation of qi promoting cold expelling; Removing toxic substances and promoting subsidence of swelling.Main anemofrigid cold; Headache; Rheumatic arthralgia; Numb limbs and tense tendons; Dysentery; Intestinal is scorching; Traumatic injury; Sore swollen toxin; Urticaria; Tuberculous lymphadenitis.
Hypericum przewalskii Maxim.: nature and flavor are bitter; Micro-pungent; Flat.Function cures mainly: promoting blood flow to regulate menstruation; Wind-damp dispelling; Edema.Main menoxenia; Traumatic injury; Traumatic hemorrhage; Fracture; Rheumatalgia; Edema; Dysuria; Summertime Sunstroke.
Flos Citri Sarcodactylis: the micro-hardship of property; Tepor.Function cures mainly: depressed liver-energy dispersing and QI regulating; Stomach function regulating soon every.Main stomachache due to hyperactive liver-QI attacking the stomach; Inappetence.
Herba Senecionis Kirilowi: nature and flavor are bitter; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Inducing diuresis to remove edema; Parasite killing.Main swollen pus infections furuncle and phyma; Urinary tract infection; Oedema due to nephritis; Stomatitis; Traumatic injury; Eczema; Scabies; Trichomonas vaginitis.
Radix Picriae felterrae: nature and flavor are bitter, cold in nature.Function cures mainly: heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For anemopyretic cold, laryngopharynx swelling and pain, sore throat, mumps, epigastric pain, dysentery, traumatic injury, furuncle and phyma, venom.
Radix Euphorbiae Pekinensis: nature and flavor are bitter, cold in nature, poisonous.Function cures mainly: removing water retention by purgation Shen, and profit two just.Harness the river swollen, dropsy, phlegm retention, scrofula, swollen ulcer drug.
Herba Potentillae Chinensis: nature and flavor are bitter, cold.Function cures mainly: heat-clearing and toxic substances removing, cooling blood and relieving pain.For bloody dysentery stomachache, chronic dysentery is more than, bleeding hemorrhoids, carbuncle sore tumefacting virus.
Herba Inulae: nature and flavor are bitter, pungent, salty, warm in nature.Function cures mainly: sending down the abnormal ascending QI, expectorant, row water.For affection of exogenous wind-cold, phlegm retention stores knot, cough with asthma abundant expectoration, chest and diaphragm feeling of fullness.
Cortex Meliae: nature and flavor are bitter, cold.Function cures mainly: parasite killing, treats tinea.For ascariasis, enterobiasis, abdominal pain due to worm stagnation; External treatment scabies pruritus.
Radix Tinosporae: nature and flavor bitter cold.Function cures mainly: heat-clearing and toxic substances removing, sore-throat relieving, pain relieving.For laryngopharynx swelling and pain, carbuncle furunculosis, has loose bowels, dysentery, epigastric pain.
Ramulus Uncariae Cum Uncis: function cures mainly: heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.Main children's's cold and heat, infantile convulsion, the large number of people revolves dizzy, suppressing liver-wind, and except heat in the heart, children's's infantile tic is suffered from abdominal pain, and sends out macule.
Oleum Terebinthinae: function cures mainly: for alleviating myalgia, arthralgia, neuralgia and spraining.
Herba Swertiae Mileensis: bitter in the mouth, sweet, cold in nature.Function cures mainly: liver heat removing function of gallbladder promoting, clearing away heat-damp and promoting diuresis, for dampness-heat in the liver and gallbladder, and jaundice dark coloured urine, gallbladder-distention hypochondriac pain, the puckery pain of pyretic stranguria.
Ramulus Et Folium Picrasmae: cold in nature, bitter in the mouth.Function cures mainly: heat-clearing and toxic substances removing; Removing dampness and killing parasites.Your Majesty's respiratory tract infection; Pneumonia; Acute gastroenteritis; Dysentery; Biliary tract infection; Furuncle; Scabies; Eczema; Burn due to hot liquid or fire; Venom.For anemopyretic cold, laryngopharynx swelling and pain, diarrhoea dysentery, eczema, furuncle, venom.For anemopyretic cold, laryngopharynx swelling and pain, diarrhoea dysentery, eczema, furuncle, venom.
Cacumen Platycladi: nature and flavor are bitter, puckery, cold.Function cures mainly: cooling blood for hemostasis, preventing phlegm from forming and stopping coughing, growing and blacking hair.For spitting blood, epistaxis, spitting of blood, has blood in stool, metrostaxis, cough due to lung-heat, heat in blood alopecia, early whitening of beard and hair.
Radix Bupleuri: nature and flavor are bitter, be slightly cold.Function cures mainly: reconciling superficies and interior, soothing the liver yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.
Herba Patriniae: cool in nature, acrid in the mouth, hardship.Function cures mainly: heat-clearing and toxic substances removing, removing blood stasis and expelling pus.For appendicitis, dysentery, enteritis, hepatitis, eye conjunctivitis, postnatal blood stasis stomachache, carbuncle furuncle.
Olibanum: property is pungent, bitter, temperature.Function cures mainly: blood-activating and qi-promoting pain relieving, detumescence and promoting granulation.For obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, lump in the abdomen is suffered from abdominal pain, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection.
Fructus Leonuri: property is pungent, bitter, is slightly cold.Function cures mainly: promoting blood flow to regulate menstruation, liver heat removing and eyesight improving.For menoxenia, amenorrhea dysmenorrhea, cataract, dizzy distending pain.
Radix Notoginseng: sweet, the micro-hardship of property, temperature.Function cures mainly: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Rhizoma Gastrodiae: property is sweet is flat.Function cures mainly: control dizzy pupil, and wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia, aphasia, pediatric epilepsy scared wind symptom.
Fructus Viticis: for anemopyretic cold, headache wind syndrome of head.The pungent wind that can fall apart of this product, be slightly cold heat clearing away, frivolous up, and the heresy of main loose women's head-ornaments, has the effect of wind-expelling pain-stopping, with controlling affection due to external wind and heat, headache and dizzy.
Cortex cinnamomi japonici (Ramulus Cinnamomi) skin: function cures mainly: warming middle-JIAO is regulated the flow of vital energy; Diaphoresis expelling pathogenic factors from muscles, cold of insufficiency type and stomachache; Have loose bowels; Chills and pain of the waist and kness; Anemofrigid cold; Menoxenia, effect is classified: warming middle-JIAO QI regulating medicine; Diaphoresis expelling pathogenic factors from muscles medicine
Pheretima: function cures mainly: calentura mania and irritation, infantile convulsion, cough with asthma, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, hemiplegia LUMBRICUS is dry waits disease.External is coated with the disease such as erysipelas, dermatitis rhus.
The Radix Aucklandiae: function cures mainly: circulation of qi promoting, pain relieving, spleen invigorating, helps digestion, promoting the circulation of QI to relieve pain; Intestinal stasis relieving in tune.Main born of the same parents coerce distension foot; Abdominal distention; Tell and have loose bowels; Heavy after dysentery.For weighing after breast gastral cavity distending pain, dysentery, food stagnation does not disappear, anorexia; Middle gas is not economized; Sudden deafness; Snake bite and insect sting; Toothache.
Tremella: sweet in the mouth, light, property are flat, nontoxic.Function cures mainly: effect of existing spleen reinforcing appetizing, has again the effect of QI invigorating bowel relieving, nourishing YIN and moistening the lung.Can body immunity be strengthened, the tolerance of tumor patient to Radiotherapy chemotherapy can be strengthened again.
Clinical data:
For showing the therapeutic effect of medicine of the present invention, the present invention carries out the clinical research of system through 100 routine migraine, and 100 routine cases all derive from development zone in Qingdao hospital.
Treatment group: choose 50 examples by random method, take Drug therapy of the present invention 4 weeks.
Matched group: choose 50 examples by random method, takes flunarizine treatment 4 weeks.
Two groups in the state of an illness, sex, age, the course of disease etc. through statistical procedures no significant difference.
Instructions of taking: treatment group: the decoction 230 milliliters sooner or later respectively once taking medicine of the present invention every day, treats 4 weeks.Matched group: give lamivudine, one time 1, every day 2 times, buccal after the meal, treats 4 weeks.
Observation index and method
With reference to the standard of " new Chinese medicine guideline of clinical investigations ".
Treatment group, cures 40 examples, effective 10 examples, invalid 0 example, total effective rate 100%.Matched group, cures 30 examples, effective 10 examples, invalid 10 examples, total effective rate 80%.Between two groups, difference has very significant, and treatment group is obviously better than matched group.
Detailed description of the invention
The invention provides one and be used for the treatment of migrainous medicine, for making object of the present invention, technical scheme and effect clearly, clearly, the present invention is described in more detail below.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
Embodiment 1
One is used for the treatment of migrainous medicine, according to weight portion, it comprises following component: conyza blinii 5 parts, Folium Apocyni Veneti 5 parts, Rhizoma Fagopyri Dibotryis 4 parts, Radix Saposhnikoviae 1 part, Arisaema Cum Bile 5 parts, Semen Cassiae 5 parts, Radix Polygalae 1 part, Rhizoma Chuanxiong 1 part, Flos Eriocauli 3 parts, the Radix Angelicae Dahuricae 5 parts, Cortex Sorbariae Arboreae 3 parts, Herba Diclipterae Chinensis 5 parts, Radix Rumicis Crispi 1 part, Fructus Setariae Germinatus 5 parts, Herba lysimachiae capillipedis 3 parts, Folium et Cacumen Viburni Sargentii 5 parts, Lindera angustifolia Cheng 1 part, Hypericum przewalskii Maxim. 5 parts, Flos Citri Sarcodactylis 5 parts, Herba Senecionis Kirilowi 5 parts, Radix Picriae felterrae 5 parts, 5 parts, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis 5 parts, Herba Inulae 1 part, Cortex Meliae 1 part, Radix Tinosporae 1 part, Ramulus Uncariae Cum Uncis 1 part, Oleum Terebinthinae 15 parts, Herba Swertiae Mileensis 5 parts, Ramulus Et Folium Picrasmae 5 parts, Cacumen Platycladi 1 part, Radix Bupleuri 5 parts, Herba Patriniae 5 parts, Olibanum 1 part, Fructus Leonuri 1 part, Radix Notoginseng 1 part, 1 part, Rhizoma Gastrodiae, Fructus Viticis 1 part, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin 1 part, Pheretima 1 part, the Radix Aucklandiae 1 part and 5 parts, Tremella.
The preparation method of said medicine is as follows:
(1) according to above-mentioned weight by conyza blinii, Folium Apocyni Veneti, Rhizoma Fagopyri Dibotryis, Radix Saposhnikoviae, Arisaema Cum Bile, Semen Cassiae, Radix Polygalae, Rhizoma Chuanxiong, Flos Eriocauli, the Radix Angelicae Dahuricae, Cortex Sorbariae Arboreae, Herba Diclipterae Chinensis, Radix Rumicis Crispi, Fructus Setariae Germinatus, Herba lysimachiae capillipedis, Folium et Cacumen Viburni Sargentii, Lindera angustifolia Cheng, Hypericum przewalskii Maxim., Flos Citri Sarcodactylis, Herba Senecionis Kirilowi, Radix Picriae felterrae, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis, Herba Inulae, Cortex Meliae, Radix Tinosporae, Ramulus Uncariae Cum Uncis, Oleum Terebinthinae, Herba Swertiae Mileensis, Ramulus Et Folium Picrasmae, Cacumen Platycladi, Radix Bupleuri, Herba Patriniae, Olibanum, Fructus Leonuri, Radix Notoginseng, Rhizoma Gastrodiae, Fructus Viticis, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin, Pheretima, the Radix Aucklandiae, with Tremella, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:4, soak 45 minutes in water.
(2) mixture in described step (1) and soak by water, after 60 minutes, are filtered and obtain the first filtrate and filtering residue.
(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:2, then decoct 80 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.
Toxicity test: rat 60, Quan Xiong, 150 ~ 200g, be divided into 6 groups at random, often organizes 10.That is:
(1) blank group: gavage gives normal saline 10ml/kg;
(2) model group: gavage gives 10%CCl
410ml/kg;
(3) positive controls: gavage gives silibinin 5mg/kg;
(4) medicine low dose group of the present invention: gavage gives Chinese medicine composition 1g/kg of the present invention;
(5)) dosage group: 2g/kg in medicine of the present invention;
(6)) drug bolus group of the present invention: 4g/kg.Except blank group, respectively organize equal gavage give 10% ethanol, continuous 12 weeks, after 2 weeks on-tests, single gives 50%CCl
4, give 1ml25%CCl every 2 times when giving thereafter ethanol
4.Successive administration 4 weeks
Result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to rat all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Embodiment 2
One is used for the treatment of migrainous medicine, according to weight portion, it comprises following component: conyza blinii 15 parts, Folium Apocyni Veneti 11 parts, Rhizoma Fagopyri Dibotryis 10 parts, Radix Saposhnikoviae 5 parts, Arisaema Cum Bile 11 parts, Semen Cassiae 10 parts, Radix Polygalae 8 parts, Rhizoma Chuanxiong 5 parts, Flos Eriocauli 8 parts, the Radix Angelicae Dahuricae 10 parts, Cortex Sorbariae Arboreae 8 parts, Herba Diclipterae Chinensis 10 parts, Radix Rumicis Crispi 5 parts, Fructus Setariae Germinatus 8 parts, Herba lysimachiae capillipedis 7 parts, Folium et Cacumen Viburni Sargentii 10 parts, Lindera angustifolia Cheng 8 parts, Hypericum przewalskii Maxim. 10 parts, Flos Citri Sarcodactylis 10 parts, Herba Senecionis Kirilowi 10 parts, Radix Picriae felterrae 10 parts, 10 parts, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis 12 parts, Herba Inulae 5 parts, Cortex Meliae 7 parts, Radix Tinosporae 5 parts, Ramulus Uncariae Cum Uncis 5 parts, Oleum Terebinthinae 20 parts, Herba Swertiae Mileensis 15 parts, Ramulus Et Folium Picrasmae 10 parts, Cacumen Platycladi 5 parts, Radix Bupleuri 15 parts, Herba Patriniae 11 parts, Olibanum 3 parts, Fructus Leonuri 6 parts, Radix Notoginseng 3 parts, 2 parts, Rhizoma Gastrodiae, Fructus Viticis 5 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin 5 parts, Pheretima 3 parts, the Radix Aucklandiae 6 parts and 10 parts, Tremella.
The preparation method of said medicine is as follows:
(1) according to above-mentioned weight by conyza blinii, Folium Apocyni Veneti, Rhizoma Fagopyri Dibotryis, Radix Saposhnikoviae, Arisaema Cum Bile, Semen Cassiae, Radix Polygalae, Rhizoma Chuanxiong, Flos Eriocauli, the Radix Angelicae Dahuricae, Cortex Sorbariae Arboreae, Herba Diclipterae Chinensis, Radix Rumicis Crispi, Fructus Setariae Germinatus, Herba lysimachiae capillipedis, Folium et Cacumen Viburni Sargentii, Lindera angustifolia Cheng, Hypericum przewalskii Maxim., Flos Citri Sarcodactylis, Herba Senecionis Kirilowi, Radix Picriae felterrae, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis, Herba Inulae, Cortex Meliae, Radix Tinosporae, Ramulus Uncariae Cum Uncis, Oleum Terebinthinae, Herba Swertiae Mileensis, Ramulus Et Folium Picrasmae, Cacumen Platycladi, Radix Bupleuri, Herba Patriniae, Olibanum, Fructus Leonuri, Radix Notoginseng, Rhizoma Gastrodiae, Fructus Viticis, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin, Pheretima, the Radix Aucklandiae, with Tremella, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:4, soak 45 minutes in water.
(2) mixture in described step (1) and soak by water, after 60 minutes, are filtered and obtain the first filtrate and filtering residue.
(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:2, then decoct 80 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.
Embodiment 3
One is used for the treatment of migrainous medicine, according to weight portion, it comprises following component: conyza blinii 20 parts, Folium Apocyni Veneti 20 parts, Rhizoma Fagopyri Dibotryis 15 parts, Radix Saposhnikoviae 12 parts, Arisaema Cum Bile 18 parts, Semen Cassiae 15 parts, Radix Polygalae 13 parts, Rhizoma Chuanxiong 10 parts, Flos Eriocauli 14 parts, the Radix Angelicae Dahuricae 15 parts, Cortex Sorbariae Arboreae 18 parts, Herba Diclipterae Chinensis 17 parts, Radix Rumicis Crispi 10 parts, Fructus Setariae Germinatus 12 parts, Herba lysimachiae capillipedis 14 parts, Folium et Cacumen Viburni Sargentii 15 parts, Lindera angustifolia Cheng 12 parts, Hypericum przewalskii Maxim. 20 parts, Flos Citri Sarcodactylis 20 parts, Herba Senecionis Kirilowi 20 parts, Radix Picriae felterrae 20 parts, 20 parts, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis 20 parts, Herba Inulae 13 parts, Cortex Meliae 12 parts, Radix Tinosporae 12 parts, Ramulus Uncariae Cum Uncis 12 parts, Oleum Terebinthinae 32 parts, Herba Swertiae Mileensis 20 parts of parts, Ramulus Et Folium Picrasmae 15 parts, Cacumen Platycladi 10 parts, Radix Bupleuri 20 parts, Herba Patriniae 15 parts, Olibanum 13 parts, Fructus Leonuri 12 parts, Radix Notoginseng 8 parts, 8 parts, Rhizoma Gastrodiae, Fructus Viticis 10 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin 10 parts, Pheretima 8 parts, the Radix Aucklandiae 13 parts and 15 parts, Tremella.
The preparation method of said medicine is as follows:
(1) according to above-mentioned weight by conyza blinii, Folium Apocyni Veneti, Rhizoma Fagopyri Dibotryis, Radix Saposhnikoviae, Arisaema Cum Bile, Semen Cassiae, Radix Polygalae, Rhizoma Chuanxiong, Flos Eriocauli, the Radix Angelicae Dahuricae, Cortex Sorbariae Arboreae, Herba Diclipterae Chinensis, Radix Rumicis Crispi, Fructus Setariae Germinatus, Herba lysimachiae capillipedis, Folium et Cacumen Viburni Sargentii, Lindera angustifolia Cheng, Hypericum przewalskii Maxim., Flos Citri Sarcodactylis, Herba Senecionis Kirilowi, Radix Picriae felterrae, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis, Herba Inulae, Cortex Meliae, Radix Tinosporae, Ramulus Uncariae Cum Uncis, Oleum Terebinthinae, Herba Swertiae Mileensis, Ramulus Et Folium Picrasmae, Cacumen Platycladi, Radix Bupleuri, Herba Patriniae, Olibanum, Fructus Leonuri, Radix Notoginseng, Rhizoma Gastrodiae, Fructus Viticis, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin, Pheretima, the Radix Aucklandiae, with Tremella, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:4, soak 45 minutes in water.
(2) mixture in described step (1) and soak by water, after 60 minutes, are filtered and obtain the first filtrate and filtering residue.
(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:2, then decoct 80 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.
Certainly; more than illustrate and be only preferred embodiment of the present invention; the present invention is not limited to enumerate above-described embodiment; should be noted that; any those of ordinary skill in the art are under the instruction of this description; made all equivalently to substitute, obvious variant, within the essential scope all dropping on this description, protection of the present invention ought to be subject to.
Claims (2)
1. be used for the treatment of a migrainous medicine, according to weight portion, it comprises following component:
Conyza blinii 5 parts-20 parts, Folium Apocyni Veneti 5 parts-20 parts, Rhizoma Fagopyri Dibotryis 4 parts-15 parts, Radix Saposhnikoviae 1 part-12 parts, Arisaema Cum Bile 5 parts-18 parts, Semen Cassiae 5 parts-15 parts, Radix Polygalae 1 part-13 parts, Rhizoma Chuanxiong 1 part-10 parts, Flos Eriocauli 3 parts-14 parts, the Radix Angelicae Dahuricae 5 parts-15 parts, Cortex Sorbariae Arboreae 3 parts-18 parts, Herba Diclipterae Chinensis 5 parts-17 parts, Radix Rumicis Crispi 1 part-10 parts, Fructus Setariae Germinatus 5 parts-12 parts, Herba lysimachiae capillipedis 3 parts-14 parts, Folium et Cacumen Viburni Sargentii 5 parts-15 parts, Lindera angustifolia Cheng 1 part-12 parts, Hypericum przewalskii Maxim. 5 parts-20 parts, Flos Citri Sarcodactylis 5 parts-20 parts, Herba Senecionis Kirilowi 5 parts-20 parts, Radix Picriae felterrae 5 parts-20 parts, 5 parts-20 parts, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis 5 parts-20 parts, Herba Inulae 1 part-13 parts, Cortex Meliae 1 part-12 parts, Radix Tinosporae 1 part-12 parts, Ramulus Uncariae Cum Uncis 1 part-12 parts, Oleum Terebinthinae 15 parts-32 parts, Herba Swertiae Mileensis 5 parts of-20 parts of parts, Ramulus Et Folium Picrasmae 5 parts-15 parts, Cacumen Platycladi 1 part-10 parts, Radix Bupleuri 5 parts-20 parts, Herba Patriniae 5 parts-15 parts, Olibanum 1 part-13 parts, Fructus Leonuri 1 part-12 parts, Radix Notoginseng 1 part-8 parts, 1 part-8 parts, Rhizoma Gastrodiae, Fructus Viticis 1 part-10 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin 1 part-10 parts, Pheretima 1 part-8 parts, the Radix Aucklandiae 1 part-13 parts and 5 parts-15 parts, Tremella.
2. medicine according to claim 1, is characterized in that, according to weight portion, it comprises following component
Conyza blinii 15 parts, Folium Apocyni Veneti 11 parts, Rhizoma Fagopyri Dibotryis 10 parts, Radix Saposhnikoviae 5 parts, Arisaema Cum Bile 11 parts, Semen Cassiae 10 parts, Radix Polygalae 8 parts, Rhizoma Chuanxiong 5 parts, Flos Eriocauli 8 parts, the Radix Angelicae Dahuricae 10 parts, Cortex Sorbariae Arboreae 8 parts, Herba Diclipterae Chinensis 10 parts, Radix Rumicis Crispi 5 parts, Fructus Setariae Germinatus 8 parts, Herba lysimachiae capillipedis 7 parts, Folium et Cacumen Viburni Sargentii 10 parts, Lindera angustifolia Cheng 8 parts, Hypericum przewalskii Maxim. 10 parts, Flos Citri Sarcodactylis 10 parts, Herba Senecionis Kirilowi 10 parts, Radix Picriae felterrae 10 parts, 10 parts, Radix Euphorbiae Pekinensis, Herba Potentillae Chinensis 12 parts, Herba Inulae 5 parts, Cortex Meliae 7 parts, Radix Tinosporae 5 parts, Ramulus Uncariae Cum Uncis 5 parts, Oleum Terebinthinae 20 parts, Herba Swertiae Mileensis 15 parts, Ramulus Et Folium Picrasmae 10 parts, Cacumen Platycladi 5 parts, Radix Bupleuri 15 parts, Herba Patriniae 11 parts, Olibanum 3 parts, Fructus Leonuri 6 parts, Radix Notoginseng 3 parts, 2 parts, Rhizoma Gastrodiae, Fructus Viticis 5 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) skin 5 parts, Pheretima 3 parts, the Radix Aucklandiae 6 parts and 10 parts, Tremella.
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| CN201510867879.4A CN105267760A (en) | 2015-12-01 | 2015-12-01 | Medicine for treating migraine |
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| CN105030959A (en) * | 2015-07-28 | 2015-11-11 | 黄艳 | Traditional Chinese medicine for treating migraine and preparation method thereof |
| CN105031804A (en) * | 2015-06-30 | 2015-11-11 | 汤艳娥 | Chinese medicinal cap capable of treating migraine |
| CN105030998A (en) * | 2015-07-28 | 2015-11-11 | 王璐 | Traditional Chinese medicine for treating migraine |
| US9192637B1 (en) * | 2011-09-23 | 2015-11-24 | Natural Fibers Corporation | Milkweed seed oil administered to animals |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US9192637B1 (en) * | 2011-09-23 | 2015-11-24 | Natural Fibers Corporation | Milkweed seed oil administered to animals |
| CN105031804A (en) * | 2015-06-30 | 2015-11-11 | 汤艳娥 | Chinese medicinal cap capable of treating migraine |
| CN105031303A (en) * | 2015-07-01 | 2015-11-11 | 路贝贝 | Drug for treating migraine |
| CN105031329A (en) * | 2015-07-03 | 2015-11-11 | 孙钦祥 | Traditional Chinese medicine preparation used for treating liver qi stagnation-type hemicranias, and preparation method thereof |
| CN105031111A (en) * | 2015-07-28 | 2015-11-11 | 黄艳 | Traditional Chinese medicine powder for treating migraine and preparation method thereof |
| CN105030959A (en) * | 2015-07-28 | 2015-11-11 | 黄艳 | Traditional Chinese medicine for treating migraine and preparation method thereof |
| CN105030998A (en) * | 2015-07-28 | 2015-11-11 | 王璐 | Traditional Chinese medicine for treating migraine |
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