CN105267433A - Traditional Chinese veterinary medicine for improving reproductive performance of boars and preparation method and application of traditional Chinese veterinary medicine - Google Patents
Traditional Chinese veterinary medicine for improving reproductive performance of boars and preparation method and application of traditional Chinese veterinary medicine Download PDFInfo
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- CN105267433A CN105267433A CN201510690613.7A CN201510690613A CN105267433A CN 105267433 A CN105267433 A CN 105267433A CN 201510690613 A CN201510690613 A CN 201510690613A CN 105267433 A CN105267433 A CN 105267433A
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Abstract
The invention discloses a traditional Chinese veterinary medicine for improving reproductive performance of boars. The traditional Chinese veterinary medicine is a preparation prepared from, by weight, 5-10 parts of herba epimedii, 5-10 parts of cortex eucommiae, 10-15 parts of semen cuscutae, 10-15 parts of fructus lycii and 10-15 parts of fructus ligustri lucidi. The traditional Chinese veterinary medicine has the advantages of increase of semen volume and density, improvement of sperm motility, decrease of malformation rate, improvement of semen quality and the reproductive performance of the boars, simple production process, low cost and promising application prospect.
Description
Technical field
The present invention relates to and a kind ofly improve herbal medicine of boar reproductive performance and its production and use.
Background technology
In intensive plant in order to reduce cost, improving productivity effect, often adopting test-tube mode to breed.Therefore on a pig farm, often boar can provide the seminal fluid of 100-200 head sow, and therefore for middle-size and small-size pig farm, a pig farm only has 1-2 head boar, and so the health of boar and semen quality can produce tremendous influence to the productivity effect on whole pig farm.Because the frequency of utilization of boar is higher, add do not have the special nutritious diet for boar, the body constitution of boar can be caused to decline, semen quality is deteriorated, and namely semen volume and density reduce, and motility of sperm reduces, and rate of teratosperm increases.For quality of boar semen be deteriorated, existing processing method is to provide the feedstuff that nutrition is enriched more, minimizing stress, but there is no corresponding medicine to regulate.
The toxicity of natural drug own is little, in animal body less residue, safety, is badly in need of searching and can improves boar reproductive performance, namely improves semen volume and density reduction, improves motility of sperm, reduce the natural drug of rate of teratosperm.
Summary of the invention
In order to solve the problem, the invention provides and a kind ofly improve herbal medicine of boar reproductive performance and its production and use.
The invention provides a kind of raising boar reproductive performance herbal medicine, it is the preparation be prepared from by the crude drug comprising following weight proportion: Herba Epimedii 5-10 part, Cortex Eucommiae 5-10 part, Semen Cuscutae 10-15 part, Fructus Lycii 10-15 part, Fructus Ligustri Lucidi 10-15 part.
Preferably, it is the preparation be prepared from by the crude drug of following weight proportion: Herba Epimedii 10 parts, the Cortex Eucommiae 10 parts, Semen Cuscutae 12 parts, Fructus Lycii 12 parts, Fructus Ligustri Lucidi 12 parts.
Preferably, it be by the water of each raw material or/and ethanol extraction is active component, to add in medicine the preparation that conventional adjuvant or complementary composition are prepared from.
Preferably, described preparation is oral formulations.
Further preferably, described oral formulations is powder, oral liquid, granule, tablet, capsule, pill.
Present invention also offers the preparation method of aforementioned herbal medicine, it comprises the steps:
(1) each raw material is taken by weight ratio;
(2) get the water of raw material or/and ethanol extraction, be prepared into preparation with adjuvant conventional in food, health product or medicine or complementary composition.
Present invention also offers the purposes of aforementioned herbal medicine in the herbal medicine of preparation raising animal reproduction performance.
Wherein, described herbal medicine is the herbal medicine improving buck reproductive performance.
Further, described herbal medicine is the herbal medicine improving boar reproductive performance.
Further, described herbal medicine is the herbal medicine increasing semen volume, increase seminal fluid density, improve motility of sperm and/or reduction abnormal rate.
Herbal medicine of the present invention can increase semen volume and density, improves motility of sperm and reduces abnormal rate, improves semen quality, improves the reproductive performance of boar, and production technology is simple, and with low cost, application prospect is excellent.
Obviously, according to foregoing of the present invention, according to ordinary technical knowledge and the customary means of this area, not departing under the present invention's above-mentioned basic fundamental thought prerequisite, the amendment of other various ways, replacement or change can also be made.
The detailed description of the invention of form by the following examples, is described in further detail foregoing of the present invention again.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example.All technology realized based on foregoing of the present invention all belong to scope of the present invention.
Detailed description of the invention
The preparation of embodiment 1 medicine of the present invention
1, prescription: Herba Epimedii 5g, Cortex Eucommiae 5g, Semen Cuscutae 10g, Fructus Lycii 10g, Fructus Ligustri Lucidi 10g.
2, preparation method: get Semen Cuscutae and drying of Chinese wolfberry, co-grinding was the superfine powder of 300 mesh sieves, for subsequent use; Get Herba Epimedii, the Cortex Eucommiae, Fructus Ligustri Lucidi add 10 times amount distilled water immersion 5h, decoct 3 times, each 1h, merging filtrate, concentrating under reduced pressure is extractum; The superfine powder of extractum with Semen Cuscutae and Fructus Lycii is mixed homogeneously, makes granule, dry and get final product.
The preparation of embodiment 2 medicine of the present invention
1, prescription: Herba Epimedii 10g, Cortex Eucommiae 10g, Semen Cuscutae 15g, Fructus Lycii 15g, Fructus Ligustri Lucidi 15g.
2, preparation method: get Semen Cuscutae and drying of Chinese wolfberry, co-grinding was the superfine powder of 300 mesh sieves, for subsequent use; Get Herba Epimedii, the Cortex Eucommiae, Fructus Ligustri Lucidi add 10 times amount distilled water immersion 5h, decoct 3 times, each 1h, merging filtrate, concentrating under reduced pressure is extractum; The superfine powder of extractum with Semen Cuscutae and Fructus Lycii is mixed homogeneously, makes granule, dry and get final product.
The preparation of embodiment 3 medicine of the present invention
1, prescription: Herba Epimedii 10g, Cortex Eucommiae 10g, Semen Cuscutae 10g, Fructus Lycii 10g, Fructus Ligustri Lucidi 10g.
2, preparation method: get Semen Cuscutae and drying of Chinese wolfberry, co-grinding was the superfine powder of 300 mesh sieves, for subsequent use; Get Herba Epimedii, the Cortex Eucommiae, Fructus Ligustri Lucidi add 10 times amount distilled water immersion 5h, decoct 3 times, each 1h, merging filtrate, concentrating under reduced pressure is extractum; The superfine powder of extractum with Semen Cuscutae and Fructus Lycii is mixed homogeneously, makes granule, dry and get final product.
The preparation of embodiment 4 medicine of the present invention
1, prescription: Herba Epimedii 10g, Cortex Eucommiae 10g, Semen Cuscutae 12g, Fructus Lycii 12g, Fructus Ligustri Lucidi 12g.
2, preparation method: get Semen Cuscutae and drying of Chinese wolfberry, co-grinding was the superfine powder of 300 mesh sieves, for subsequent use; Get Herba Epimedii, the Cortex Eucommiae, Fructus Ligustri Lucidi add 10 times amount distilled water immersion 5h, decoct 3 times, each 1h, merging filtrate, concentrating under reduced pressure is extractum; The superfine powder of extractum with Semen Cuscutae and Fructus Lycii is mixed homogeneously, makes granule, dry and get final product.
Below by the mode of experimental example, beneficial effect of the present invention is described:
The impact of experimental example 1 pharmaceutical composition spermatogenesis of the present invention Granules on Mouse Determination of Calcium in Serum concentration, femur length and weight
1 medical material and grouping
Prepare pharmaceutical composition spermatogenesis granule of the present invention respectively according to the embodiment of the present invention 1 ~ 4, the proportioning of Herba Epimedii, the Cortex Eucommiae, Semen Cuscutae, Fructus Lycii, Fructus Ligustri Lucidi is respectively A (prepared by embodiment 1): 5:5:10:10:10; B (prepared by embodiment 2): 10:10:15:15:15; C (prepared by embodiment 3): 10:10:10:10:10; D (prepared by embodiment 4): 10:10:12:12:12, according to technique, Semen Cuscutae (T) and Fructus Lycii (G) are prepared as superfine powder respectively, Herba Epimedii (Y), the Cortex Eucommiae (DZ), Fructus Ligustri Lucidi (N) are prepared as respectively extract (to get Herba Epimedii, the Cortex Eucommiae, Fructus Ligustri Lucidi add 10 times amount distilled water immersion 5h, decoct 3 times, each 1h, merging filtrate, concentrating under reduced pressure is extractum).
2 experimental techniques
Choose boar station, Qionglai boar 50, be divided into 10 groups at random, often organize five, be respectively matched group, A, B, C, D group, matched group does not process, and A, B, C, D group after one week, takes seminal fluid assay related data according to the administration of 500g/ ton crude drug amount spice respectively in feedstuff.
3 experimental results
The results are shown in Table 1:
Table 1 spermatogenesis granule is on the impact of boar semen collection time, volume of semen, sperm concentration, motility of sperm, abnormal rate
| Project | Semen collection time s | Volume of semen ml | Sperm concentration (hundred million/ml) | Motility of sperm (%) | Rate of teratosperm |
| Matched group | 261 | 201 | 1.87 | 68.4 | 9.56 |
| Y | 261 | 202 | 1.88 | 68.7 | 9.51 |
| DZ | 263 | 203 | 1.91 | 68.6 | 9.56 |
| N | 265 | 204 | 1.95 | 68.4 | 9.42 |
| T | 267 | 201 | 1.93 | 68.9 | 9.38 |
| G | 264 | 202 | 1.82 | 69.1 | 9.44 |
| A | 271 | 214 | 2.16 | 71.6 | 9.27 |
| B | 284 | 226 | 2.35 | 72.4 | 9.15 |
| C | 276 | 219 | 2.26 | 71.5 | 9.23 |
| D | 299 | 235 | 2.51 | 73.5 | 9.02 |
Result shows:
Pharmaceutical composition spermatogenesis granule prepared by the embodiment of the present invention 1 ~ 4 all significantly can improve the reproductive performance of boar, be embodied in and extend the ejaculation time, increase semen volume and density, improve motility of sperm and also reduce abnormal rate, with Herba Epimedii, the Cortex Eucommiae, Semen Cuscutae, Fructus Lycii, Fructus Ligustri Lucidi ratio for 10:10:12:12:12 effect best;
Under identical dosage, with be used alone compared with Herba Epimedii, the Cortex Eucommiae, Semen Cuscutae, Fructus Lycii, Fructus Ligustri Lucidi, medicine spermatogenesis granule prepared by the embodiment of the present invention 1 ~ 5, the effect improving boar production is significantly better, illustrate the present invention by Herba Epimedii, the Cortex Eucommiae, Semen Cuscutae, Fructus Lycii, Fructus Ligustri Lucidi within the scope of the specific weight proportion of the present invention (Herba Epimedii 5-10 part, Cortex Eucommiae 5-10 part, Semen Cuscutae 10-15 part, Fructus Lycii 10-15 part, Fructus Ligustri Lucidi 10-15 part) combinationally use, the effect of Synergistic can be played.
Experimental example 2 pharmaceutical composition of the present invention spermatogenesis granule is on pig farm insemination of sows rate and the impact of producing sub-head number
1 experimental technique
Pharmaceutical composition spermatogenesis granule of the present invention, pharmaceutical composition of the present invention prepared by embodiment 4.
Choose medium-sized pig farm, Qionglai and carry out test statistics, (parity is close respectively the 4-10 month in 2014 to be treated breeding sow, a upper tire is without exception) be divided into two groups, often organize 40, one group by the boar semen artificial insemination do not dealt with, another group with the boar semen artificial fertilization fed containing spermatogenesis granule (D), the boar being fed with spermatogenesis granule (D) is according to the boar of 500g/ ton spice spermatogenesis particle delivery after one week in feedstuff, two groups of all the other care procedure are identical, observe statistics breeding success rate respectively and on average produce subnumber.
2 experimental results
The results are shown in Table 2:
Table 2 spermatogenesis granule is on pig farm insemination of sows rate and the impact of producing sub-head number
| Project | Breeding head number | Breed and successfully count (head) | Average product head number (head) |
| Contrast seminal fluid group | 40 | 38 | 10.6 |
| Spermatogenesis granule seminal fluid group | 40 | 40 | 11.8 |
From result, compared with matched group, the seminal fluid of spermatogenesis granule boar of feeding can improve the pregnancy rate of sow, improves and produces subnumber, illustrate that pharmaceutical composition spermatogenesis granule of the present invention significantly can improve the semen quality of boar, improve the reproductive performance of boar.
To sum up, herbal medicine of the present invention can increase semen volume and density, improves motility of sperm and reduces abnormal rate, improves semen quality, improves the reproductive performance of boar, and production technology is simple, and with low cost, application prospect is excellent.
Claims (10)
1. improve a boar reproductive performance herbal medicine, it is characterized in that: it is the preparation be prepared from by the crude drug of following weight proportion: Herba Epimedii 5-10 part, Cortex Eucommiae 5-10 part, Semen Cuscutae 10-15 part, Fructus Lycii 10-15 part, Fructus Ligustri Lucidi 10-15 part.
2. herbal medicine according to claim 1, is characterized in that: it is the preparation be prepared from by the crude drug of following weight proportion: Herba Epimedii 10 parts, the Cortex Eucommiae 10 parts, Semen Cuscutae 12 parts, Fructus Lycii 12 parts, Fructus Ligustri Lucidi 12 parts.
3. the herbal medicine according to claim 1 or 2 any one, is characterized in that: it be by the water of each raw material or/and ethanol extraction is active component, to add in medicine the preparation that conventional adjuvant or complementary composition are prepared from.
4. herbal medicine according to claim 3, is characterized in that: described preparation is oral formulations.
5. herbal medicine according to claim 4, is characterized in that: described oral formulations is granule, tablet, powder, oral liquid, capsule, pill.
6. prepare a method for herbal medicine described in claim 1-5 any one, it comprises the steps:
(1) each raw material is taken by weight ratio;
(2) get the water of raw material or/and ethanol extraction, be prepared into preparation with adjuvant conventional in food, health product or medicine or complementary composition.
7. herbal medicine described in claim 1-5 any one improves the purposes in the herbal medicine of animal reproduction performance in preparation.
8. purposes according to claim 7, is characterized in that: described herbal medicine is the herbal medicine improving buck reproductive performance.
9. purposes according to claim 8, is characterized in that: described herbal medicine is the herbal medicine improving boar reproductive performance.
10. purposes according to claim 7, is characterized in that: described herbal medicine is the herbal medicine increasing semen volume, increase seminal fluid density, improve motility of sperm and/or reduction abnormal rate.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105685504A (en) * | 2016-02-03 | 2016-06-22 | 和县凤台山煜新畜牧有限公司 | Breeding boar aphrodisiac powder |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103053859A (en) * | 2013-01-31 | 2013-04-24 | 曾龙 | Compound Chinese medicinal herb premix for breeding boars |
| CN104381634A (en) * | 2014-10-30 | 2015-03-04 | 广西博白扬翔宝中宝饲料有限责任公司 | Traditional Chinese medicine compound boar feed capable of improving quality of boar semen |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103053859A (en) * | 2013-01-31 | 2013-04-24 | 曾龙 | Compound Chinese medicinal herb premix for breeding boars |
| CN104381634A (en) * | 2014-10-30 | 2015-03-04 | 广西博白扬翔宝中宝饲料有限责任公司 | Traditional Chinese medicine compound boar feed capable of improving quality of boar semen |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105685504A (en) * | 2016-02-03 | 2016-06-22 | 和县凤台山煜新畜牧有限公司 | Breeding boar aphrodisiac powder |
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