CN105267411A - Medicine composition for treating fracture - Google Patents

Medicine composition for treating fracture Download PDF

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CN105267411A
CN105267411A CN201510113241.1A CN201510113241A CN105267411A CN 105267411 A CN105267411 A CN 105267411A CN 201510113241 A CN201510113241 A CN 201510113241A CN 105267411 A CN105267411 A CN 105267411A
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parts
radix
herba
component
external application
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CN105267411B (en
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张桂生
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Abstract

The invention discloses a medicine composition for treating fracture, and belongs to the traditional Chinese medicine technology field. The medicine composition is composed of an oral component and an external application component, the oral component is prepared from Chinese gall, dried orange peel, myrrh, solidago decurrens lour., magnolia cortex, strychnos nuxvomica, radices trichosanthis, radix rehmanniae preparata, rheum officinale and dahurian angelica root according to certain ratios, and the external application component is prepared from native copper, herba artemisiae anomalae, frankincense, sambucus chinensis, dandelion, gardeniajasminoides, radix ilicis asprellae, desmodium, coix seeds, cordate houttuynia, dipsacus root and rice vinegar according to certain ratios. The medicine composition can promote growth of fresh and tendon, bone jointing and tendon jointing are rapid, and the purpose of curing fracture is achieved rapidly. The treatment effects are good, the treatment course is short, and the medicine composition is safe and has no side effects.

Description

A kind of pharmaceutical composition for the treatment of fracture
Technical field
The present invention relates to a kind of orthopaedics medicine, a kind of pharmaceutical composition for the treatment of fracture, belongs to technical field of Chinese medicines specifically.
Background technology
The bone parts that mainly wound of fracturing causes or a kind of disease ruptured completely are common Orthopeadic Surgery diseases.At present, usually plaster fixing is adopted after adopting operative treatment or bone docking clinically, this Therapeutic Method mainly relies on patient's autosynthesis ability that fracture site is healed, be equipped with the medicine of blood circulation promoting and blood stasis dispelling or anti-inflammatory analgetic class simultaneously, its growth of spur is slow, treatment cycle long, costly, make patient suffer huge misery for a long time.And Traditional Chinese Medicine is often selected to take the medicines such as Radix Notoginseng Tabellae, pill for traumatic injuries or Cortex torricelliae tiliifoliae and is treated, but administration time is long, DeGrain, ubiquity healing is slow, the phenomenon of Bone nonunion, thus a kind of therapeutic effect is badly in need of good, the medicine of the treatment fracture of instant effect.
Summary of the invention
For problems of the prior art, the invention provides a kind of pharmaceutical composition for the treatment of fracture, this pharmaceutical composition comprises component for oral administration and external application component, treating both the principal and secondary aspects of a disease, can promote that meat, muscle grow, and synthetism, to connect muscle rapid, reach the object of heal fractures fast, therapeutic effect is good, short treating period, and safety has no side effect.
The present invention is by the following technical solutions:
Treat a pharmaceutical composition for fracture, it comprises oral component and external application component:
Described oral component is made up of the crude drug of following weight portion: Galla Chinensis 10-20 part, Pericarpium Citri Reticulatae 15-30 part, Myrrha 20-40 part, Herba Solidaginis 10-20 part, Cortex Magnoliae Officinalis 10-20 part, Semen Strychni 20-30 part, Radix Trichosanthis 10-20 part, Radix Rehmanniae Preparata 8-15 part, Radix Et Rhizoma Rhei 8-15 part, Radix Angelicae Dahuricae 10-15 part;
Described external application component is made up of the crude drug of following weight portion: Pyritum 30-50 part, Herba Artemisiae Anomalae 20-40 part, Olibanum 10-20 part, Herba Sambuci Chiensis 10-20 part, Herba Taraxaci 15-25 part, SHANZHIZI 20-30 part, Radix Ilicis Asprellae 20-30 part, Herba Lysimachiae 10-15 part, Semen Coicis 8-12 part, Herba Houttuyniae 8-16 part, Radix Dipsaci 10-20 part, rice vinegar 120-180 part.
Preferably, the pharmaceutical composition of described treatment fracture, it comprises oral component and external application component:
Described oral component is made up of the crude drug of following weight portion: Galla Chinensis 15 parts, Pericarpium Citri Reticulatae 25 parts, Myrrha 30 parts, Herba Solidaginis 15 parts, Cortex Magnoliae Officinalis 15 parts, Semen Strychni 25 parts, Radix Trichosanthis 15 parts, 12 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 12 parts, the Radix Angelicae Dahuricae 13 parts;
Described external application component is made up of the crude drug of following weight portion: Pyritum 40 parts, Herba Artemisiae Anomalae 30 parts, Olibanum 15 parts, Herba Sambuci Chiensis 15 parts, Herba Taraxaci 20 parts, SHANZHIZI 25 parts, Radix Ilicis Asprellae 25 parts, Herba Lysimachiae 12 parts, Semen Coicis 10 parts, Herba Houttuyniae 12 parts, Radix Dipsaci 15 parts, rice vinegar 150 parts.
The pharmacological action of medicine of the present invention is as follows:
Galla Chinensis: sour in the mouth, puckery, cold in nature; Return lung, large intestine, kidney channel; There is pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, arresting sweating, hemostasis, effect of removing dampness sore.Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature; Return lung, spleen channel; There is regulating qi-flowing for strengthening spleen, effect of drying dampness to eliminate phlegm.Myrrha: bitter, pungent is flat; Enter liver, spleen, the heart, kidney channel; There is eliminating stasis to stop pain, effect of externally used detumescence granulation promoting.Herba Solidaginis: pungent, bitter, cool; Return lung, Liver Channel; There is heat-clearing and toxic substances removing, effect of dispelling wind and heat pathogens.Cortex Magnoliae Officinalis: bitter in the mouth, pungent, warm in nature; Return spleen, stomach, lung, large intestine channel; Have dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full effect.Semen Strychni: bitter, warm; Return liver, spleen channel; There is removing obstruction in the collateral to relieve pain, the effect of mass dissipating and swelling eliminating.Radix Trichosanthis: sweet, micro-hardship, is slightly cold; Attach to the lung and stomach meridians; There is clearing away heat-fire, promoting the production of body fluid to quench thirst, effect of detumescence and apocenosis.Radix Rehmanniae Preparata: sweet, tepor; Return liver, kidney channel; There is yin nourishing of enriching blood, effect of life essence-filling, marrow-benefitting.Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature, nontoxic; Return spleen, stomach, large intestine, liver, pericardium channel; There is purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, effect of eliminating blood stasis and inducing menstruation.The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature; Return lung, spleen, stomach warp; There is the cold expelling that induces sweat, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis, effect of dispelling wind for relieving itching.Pyritum: pungent is flat; Return Liver Channel; There is eliminating stasis to stop pain, effect of reunion of fractured tendons and bones.Herba Artemisiae Anomalae: bitter, warm; GUIXIN, liver, spleen channel; There is removing blood stasis stimulate the menstrual flow, effect of healing up sore and subduing swelling.Olibanum: pungent, bitter, temperature; GUIXIN, liver, spleen channel; There is blood-activating and qi-promoting pain relieving, effect of detumescence and promoting granulation.Herba Sambuci Chiensis: warm in nature, bitter in the mouth; Toil, cold; There is promoting blood circulation to remove blood stasis, soothing liver and strengthening spleen, dispelling, collateral-activating, effect of diaphoresis diuresis.Herba Taraxaci: bitter sweet, cold; Enter liver, stomach warp; There is heat-clearing and toxic substances removing, effect of diuresis eliminating stagnation.SHANZHIZI: bitter, cold; Enter the heart, liver, lung, stomach warp; There is heat clearing away, pathogenic fire purging, effect of removing heat from blood.Radix Ilicis Asprellae: bitter, sweet, cool; Return lung, liver, large intestine channel; There is heat-clearing and toxic substances removing, promoting the production of body fluid to quench thirst, effect of dissipating blood stasis.Herba Lysimachiae: sweet in the mouth, micro-hardship, cool in nature; Return liver, gallbladder, kidney, urinary bladder channel; There is effect of relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Semen Coicis: sweet in the mouth, light, cool in nature; Return spleen, stomach, lung meridian; Favourable water permeation wets, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, the effect of detoxicating and resolving stagnation of pathogens.Herba Houttuyniae: acrid in the mouth, cold; Return lung meridian; There is heat-clearing and toxic substances removing, effect of inducing diuresis to remove edema.Radix Dipsaci: bitter, sweet, pungent, tepor; Return liver, kidney channel; There is invigorating the liver and kidney, promoting the circulation of blood arteries and veins, effect of reuniting the fractured tendons and bones.
In medicine of the present invention, the preparation method of described oral component is as follows:
(1) take above-mentioned formula ratio material medicine according to quantity, after adding 800-1000ml cold water soak 1.5-2 hour wherein, first to burn to boiling slow fire boiling again 30 minutes with intense fire, filter to obtain a filtered juice;
(2) continuing to add water 500ml decoction to seething with excitement latter 25 minutes in filtering residue, filtering to obtain secondary filtered juice;
(3) first and second filtered juice merged, heating is concentrated into 300ml.
The preparation method of described external application component is as follows:
(1) material medicine except rice vinegar is pulverized grind into powder respectively, after crossing 80-100 mesh sieve, mix homogeneously obtains mixed powder;
(2) get formula ratio rice vinegar to mix in mixed powder and be modulated into pasty medicament and get final product.
The usage of medicine of the present invention and consumption: the present invention's oral component one side is potion, potion on the one, one day twice, respectively take 150ml in 1 hour after meal sooner or later.External application component: get the pasty medicament uniform application made in advance and spread on affected part, according to affected part area Reasonable adjustment drug dose, generally spreading out and being coated with thickness is about 0.5cm, then with medical bandage wrapping (should not be too tight and too loose), within 1 day, changes dressings once.Oral component and external application component simultaneously with the use of, within 10 days, be 1 course for the treatment of, general 1-4 can cure a course for the treatment of.
The invention has the beneficial effects as follows: the present invention's all medicines compatibility is scientific and reasonable, this pharmaceutical composition has reason QI and blood meridian, reducing swelling and alleviating pain, effect of blood circulation promoting and blood stasis dispelling, the medicine of dual-purpose tonifying QI to promote blood circulation, passage, nourishing blood, bactericidal antiphlogistic, granulation promoting pain relieving simultaneously, thus reach the effect that can promote growth of spur, removing blood stasis with potent drugs synthetism, continuous muscle fast.All kinds of fracture instant effect of this Drug therapy, healing effect is good, has no side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment 1
Treat a pharmaceutical composition for fracture, it comprises oral component and external application component:
Oral component is made up of the crude drug of following weight: Galla Chinensis 10g, Pericarpium Citri Reticulatae 15g, Myrrha 20g, Herba Solidaginis 10g, Cortex Magnoliae Officinalis 10g, Semen Strychni 20g, Radix Trichosanthis 10g, Radix Rehmanniae Preparata 8g, Radix Et Rhizoma Rhei 8g, Radix Angelicae Dahuricae 10g.
External application component is made up of the crude drug of following weight: Pyritum 30g, Herba Artemisiae Anomalae 20g, Olibanum 10g, Herba Sambuci Chiensis 10g, Herba Taraxaci 15g, SHANZHIZI 20g, Radix Ilicis Asprellae 20g, Herba Lysimachiae 10g, Semen Coicis 8g, Herba Houttuyniae 8g, Radix Dipsaci 10g, rice vinegar 120g.
The preparation method of the oral component of said medicine is as follows:
(1) take above-mentioned formula ratio material medicine according to quantity, after adding 800-1000ml cold water soak 1.5-2 hour wherein, first to burn to boiling slow fire boiling again 30 minutes with intense fire, filter to obtain a filtered juice;
(2) continuing to add water 500ml decoction to seething with excitement latter 25 minutes in filtering residue, filtering to obtain secondary filtered juice;
(3) first and second filtered juice merged, heating is concentrated into 300ml.
The preparation method of said medicine external application component is as follows:
(1) material medicine except rice vinegar is pulverized grind into powder respectively, after crossing 80-100 mesh sieve, mix homogeneously obtains mixed powder;
(2) get formula ratio rice vinegar to mix in mixed powder and be modulated into pasty medicament and get final product.
Embodiment 2
Treat a pharmaceutical composition for fracture, it comprises oral component and external application component:
Oral component is made up of the crude drug of following weight: Galla Chinensis 15g, Pericarpium Citri Reticulatae 25g, Myrrha 30g, Herba Solidaginis 15g, Cortex Magnoliae Officinalis 15g, Semen Strychni 25g, Radix Trichosanthis 15g, Radix Rehmanniae Preparata 12g, Radix Et Rhizoma Rhei 12g, Radix Angelicae Dahuricae 13g.
External application component is made up of the crude drug of following weight: Pyritum 40g, Herba Artemisiae Anomalae 30g, Olibanum 15g, Herba Sambuci Chiensis 15g, Herba Taraxaci 20g, SHANZHIZI 25g, Radix Ilicis Asprellae 25g, Herba Lysimachiae 12g, Semen Coicis 10g, Herba Houttuyniae 12g, Radix Dipsaci 15g, rice vinegar 150g.
The preparation method of the present embodiment pharmaceutical composition is with embodiment 1.
Embodiment 3
Treat a pharmaceutical composition for fracture, it comprises oral component and external application component:
Oral component is made up of the crude drug of following weight: Galla Chinensis 20g, Pericarpium Citri Reticulatae 30g, Myrrha 40g, Herba Solidaginis 20g, Cortex Magnoliae Officinalis 20g, Semen Strychni 30g, Radix Trichosanthis 20g, Radix Rehmanniae Preparata 15g, Radix Et Rhizoma Rhei 15g, Radix Angelicae Dahuricae 15g;
External application component is made up of the crude drug of following weight: Pyritum 50g, Herba Artemisiae Anomalae 40g, Olibanum 20g, Herba Sambuci Chiensis 20g, Herba Taraxaci 25g, SHANZHIZI 30g, Radix Ilicis Asprellae 30g, Herba Lysimachiae 15g, Semen Coicis 12g, Herba Houttuyniae 16g, Radix Dipsaci 20g, rice vinegar 180g.
The preparation method of the present embodiment pharmaceutical composition is with embodiment 1.
Embodiment 4
Treat a pharmaceutical composition for fracture, it comprises oral component and external application component:
Oral component is made up of the crude drug of following weight: Galla Chinensis 18g, Pericarpium Citri Reticulatae 25g, Myrrha 35g, Herba Solidaginis 18g, Cortex Magnoliae Officinalis 15g, Semen Strychni 24g, Radix Trichosanthis 12g, Radix Rehmanniae Preparata 10g, Radix Et Rhizoma Rhei 10g, Radix Angelicae Dahuricae 12g.
External application component is made up of the crude drug of following weight: Pyritum 45g, Herba Artemisiae Anomalae 35g, Olibanum 18g, Herba Sambuci Chiensis 15g, Herba Taraxaci 22g, SHANZHIZI 27g, Radix Ilicis Asprellae 28g, Herba Lysimachiae 10g, Semen Coicis 9g, Herba Houttuyniae 14g, Radix Dipsaci 18g, rice vinegar 160g.
The preparation method of the present embodiment pharmaceutical composition is with embodiment 1.
Clinical practice example
1. clinical data: fracture patient 260 example is accepted in random selecting outpatient service for medical treatment, mostly is the caused fracture of external force.Wherein man 155 example, female 105 example, the age 15-55 year, the mean age is 38 years old.
2. diagnostic criteria: can make a definite diagnosis according to clinical manifestation and imaging examination.
3. Therapeutic Method: use the medicine that the embodiment of the present invention 2 is obtained, the while of oral component and external application component with the use of, within 10 days, be 1 course for the treatment of.Oral component one side is potion, potion on the one, one day twice, sooner or later within 1 hour after meal, respectively takes 150ml.External application component: get the pasty medicament uniform application made in advance and spread on affected part, according to affected part area Reasonable adjustment drug dose, generally spreading out and being coated with thickness is about 0.5cm, then with medical bandage wrapping (should not be too tight and too loose), within 1 day, changes dressings 1 time.General 1-4 can cure a course for the treatment of.
4. curative effect determinate standard:
Cure: be foundation with X-ray image, fracture line is fuzzy, has continuous callus by fracture line, and swelling pain sense disappears, and patient can be normally freely movable.
Take a turn for the better: callus formation is obvious, holds fracture site, swelling pain sense disappears, and patient can local movement.
Invalid: without callus formation or there is a small amount of callus formation, swelling pain sense is obvious.
5. therapeutic outcome: in table 1.
Table 1 clinical treatment outcome
Case Cure n Improvement n Invalid n Total effectively n(%)
260 223 36 1 149(99.6)
As can be seen from the above results, pharmaceutical composition of the present invention is treated fracture patient 260 example, and result cures 223 examples, and take a turn for the better 36 examples, and invalid 1 example, total effective rate reaches 99.6%.
Model case
Example 1: Lee, female, 24 years old, patient, in being wounded by electro-tricycle on the way to office, felt after wound that right elbow continues severe pain, and without radiation, limitation of activity, sends medical rear x-ray inspection to hospital and be diagnosed as right humerus comminuted fracture of lower end.After manual reduction is fixing, the liniment that the external application embodiment of the present invention 2 is obtained, be equipped with after oral component treats 1 course for the treatment of, pain alleviates most simultaneously, local swelling is vanished from sight substantially, and after rear continuation uses 2 courses for the treatment of of pharmaceutical composition of the present invention, patient is movable as ordinary person.
Example 2: Cai so-and-so, man, 55 years old, patient fell injured accidentally from stair, namely felt right hip persistence severe pain, limitation of activity, walking of can not standing after wound.Right fracture of femoral neck is shown through x-ray inspection.After using 2 courses for the treatment of of pharmaceutical composition of the embodiment of the present invention 3, patient fully recovers.
Example 3: connect certain, man, 20 years old, patient drives car and front truck knocked into the back and causes left leg swelling obviously, can and bony crepitus and bone rubbing feeling, x-ray inspection shows left lower limb fracture of shaft of tibia.After manual reduction, after 1 course for the treatment of of pharmaceutical composition using the embodiment of the present invention 1 to prepare, patient's swelling and pain disappear more than half, and continue to use patient's recovery from illness after 3 courses for the treatment of of medicine of the present invention, activity freely.
Example 4: Chen, female, 16 years old, patient occurred after high falling that right lower extremity is hemorrhage, pain accompany right thigh swelling, limitation of activity.Right lateral thigh shaft fracture is diagnosed as through x-ray inspection.Use 1 course for the treatment of of pharmaceutical composition of the embodiment of the present invention 4 after maneuver replacement and fixation after; swelling, pain disappear more than half; X-ray examination callus formation is obvious; patient can local movement; after rear continuation uses 2 courses for the treatment of of medicine of the present invention; clinical symptoms all disappears, and patient can normal activity.

Claims (2)

1. treat a pharmaceutical composition for fracture, it is characterized in that, it comprises oral component and external application component:
Described oral component is made up of the crude drug of following weight portion: Galla Chinensis 10-20 part, Pericarpium Citri Reticulatae 15-30 part, Myrrha 20-40 part, Herba Solidaginis 10-20 part, Cortex Magnoliae Officinalis 10-20 part, Semen Strychni 20-30 part, Radix Trichosanthis 10-20 part, Radix Rehmanniae Preparata 8-15 part, Radix Et Rhizoma Rhei 8-15 part, Radix Angelicae Dahuricae 10-15 part;
Described external application component is made up of the crude drug of following weight portion: Pyritum 30-50 part, Herba Artemisiae Anomalae 20-40 part, Olibanum 10-20 part, Herba Sambuci Chiensis 10-20 part, Herba Taraxaci 15-25 part, SHANZHIZI 20-30 part, Radix Ilicis Asprellae 20-30 part, Herba Lysimachiae 10-15 part, Semen Coicis 8-12 part, Herba Houttuyniae 8-16 part, Radix Dipsaci 10-20 part, rice vinegar 120-180 part.
2. the pharmaceutical composition for the treatment of fracture according to claim 1, it is characterized in that, it comprises oral component and external application component:
Described oral component is made up of the crude drug of following weight portion: Galla Chinensis 15 parts, Pericarpium Citri Reticulatae 25 parts, Myrrha 30 parts, Herba Solidaginis 15 parts, Cortex Magnoliae Officinalis 15 parts, Semen Strychni 25 parts, Radix Trichosanthis 15 parts, 12 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 12 parts, the Radix Angelicae Dahuricae 13 parts;
Described external application component is made up of the crude drug of following weight portion: Pyritum 40 parts, Herba Artemisiae Anomalae 30 parts, Olibanum 15 parts, Herba Sambuci Chiensis 15 parts, Herba Taraxaci 20 parts, SHANZHIZI 25 parts, Radix Ilicis Asprellae 25 parts, Herba Lysimachiae 12 parts, Semen Coicis 10 parts, Herba Houttuyniae 12 parts, Radix Dipsaci 15 parts, rice vinegar 150 parts.
CN201510113241.1A 2015-03-16 2015-03-16 A kind of pharmaceutical composition for treating fracture Expired - Fee Related CN105267411B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1435188A (en) * 2002-01-28 2003-08-13 张作明 Bone-setting instant granules and capsules, and preparing process thereof
CN1565526A (en) * 2003-06-19 2005-01-19 程时林 Orthopaedics used externally applied plaster with integrated functions of stopping pain, eliminating swelling and promoting bone fracture recovery
CN102343076A (en) * 2011-10-14 2012-02-08 玉林市骨科医院 Traumatic injury treatment ointment medicament for external application and production method thereof
CN103417780A (en) * 2013-08-08 2013-12-04 周杰山 Bone fracture treatment plaster

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1435188A (en) * 2002-01-28 2003-08-13 张作明 Bone-setting instant granules and capsules, and preparing process thereof
CN1565526A (en) * 2003-06-19 2005-01-19 程时林 Orthopaedics used externally applied plaster with integrated functions of stopping pain, eliminating swelling and promoting bone fracture recovery
CN102343076A (en) * 2011-10-14 2012-02-08 玉林市骨科医院 Traumatic injury treatment ointment medicament for external application and production method thereof
CN103417780A (en) * 2013-08-08 2013-12-04 周杰山 Bone fracture treatment plaster

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