CN105263461B - 用于治疗化合物的口服递送的装置 - Google Patents

用于治疗化合物的口服递送的装置 Download PDF

Info

Publication number
CN105263461B
CN105263461B CN201480015725.6A CN201480015725A CN105263461B CN 105263461 B CN105263461 B CN 105263461B CN 201480015725 A CN201480015725 A CN 201480015725A CN 105263461 B CN105263461 B CN 105263461B
Authority
CN
China
Prior art keywords
capsule
balloon
piston
compartment
wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480015725.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN105263461A (zh
Inventor
米尔·伊姆兰
彼得·赫尔曼
贝博·赛义德
蒂莫西·H·威廉姆斯
昌·金弘
格雷格·麦瑟德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rani Therapeutics LLC
Original Assignee
Rani Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/837,025 external-priority patent/US8734429B2/en
Application filed by Rani Therapeutics LLC filed Critical Rani Therapeutics LLC
Publication of CN105263461A publication Critical patent/CN105263461A/zh
Application granted granted Critical
Publication of CN105263461B publication Critical patent/CN105263461B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201480015725.6A 2013-03-15 2014-03-12 用于治疗化合物的口服递送的装置 Active CN105263461B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/837,025 2013-03-15
US13/837,025 US8734429B2 (en) 2010-12-23 2013-03-15 Device, system and methods for the oral delivery of therapeutic compounds
PCT/US2014/024385 WO2014159604A1 (en) 2013-03-15 2014-03-12 Device for oral delivery of therapeutic compounds

Publications (2)

Publication Number Publication Date
CN105263461A CN105263461A (zh) 2016-01-20
CN105263461B true CN105263461B (zh) 2019-09-10

Family

ID=51625211

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480015725.6A Active CN105263461B (zh) 2013-03-15 2014-03-12 用于治疗化合物的口服递送的装置

Country Status (10)

Country Link
EP (2) EP2968071B1 (https=)
JP (5) JP6796484B2 (https=)
CN (1) CN105263461B (https=)
AU (4) AU2014240401B2 (https=)
CA (3) CA2901923C (https=)
DK (1) DK2968071T3 (https=)
ES (1) ES2897795T3 (https=)
PL (1) PL2968071T3 (https=)
PT (1) PT2968071T (https=)
WO (1) WO2014159604A1 (https=)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8682440B2 (en) 2009-08-03 2014-03-25 Incube Labs, Llc Swallowable capsule and method for stimulating incretin production within the intestinal tract
US8721620B2 (en) 2009-12-24 2014-05-13 Rani Therapeutics, Llc Swallowable drug delivery device and methods of drug delivery
US9402807B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8809269B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9861683B2 (en) 2010-12-23 2018-01-09 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9259386B2 (en) 2010-12-23 2016-02-16 Rani Therapeutics, Llc Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9284367B2 (en) 2010-12-23 2016-03-15 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9283179B2 (en) 2010-12-23 2016-03-15 Rani Therapeutics, Llc GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8980822B2 (en) 2010-12-23 2015-03-17 Rani Therapeutics, Llc Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8846040B2 (en) 2010-12-23 2014-09-30 Rani Therapeutics, Llc Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9415004B2 (en) 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9629799B2 (en) 2010-12-23 2017-04-25 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8969293B2 (en) 2010-12-23 2015-03-03 Rani Therapeutics, Llc Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8734429B2 (en) 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US9402806B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US10639272B2 (en) 2010-12-23 2020-05-05 Rani Therapeutics, Llc Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device
EP2968071B1 (en) * 2013-03-15 2021-08-04 Rani Therapeutics, LLC Device for oral delivery of therapeutic compounds
US10220003B2 (en) * 2016-03-09 2019-03-05 Incube Labs, Llc Methods and articles for delivering viable cells into solid tissue
KR20230042759A (ko) * 2016-09-09 2023-03-29 비오라 쎄라퓨틱스, 인크. 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
WO2018213579A1 (en) * 2017-05-17 2018-11-22 Massachusetts Institute Of Technology Self-actuating articles
US10675248B2 (en) * 2018-08-14 2020-06-09 Alma Therapeutics Ltd. Expandable pill
US12128133B2 (en) 2018-09-25 2024-10-29 Rani Therapeutics, Llc Ingestible device with expandable enclosure
CN109621169B (zh) * 2019-01-09 2021-06-08 李红岩 一种产科观察治疗仪
JP7420819B2 (ja) * 2019-02-01 2024-01-23 ノボ・ノルデイスク・エー／エス 作動機構を有する医療デバイス
AU2020360407B2 (en) * 2019-10-01 2026-04-09 Rani Therapeutics, Llc Self-sizing device for delivering a formulation to a lumen wall
WO2021146296A1 (en) * 2020-01-14 2021-07-22 Rani Therapeutics, Llc Swallowable devices for drug delivery in an intestinal tract
WO2021198353A1 (en) * 2020-03-31 2021-10-07 Danmarks Tekniske Universitet A flexible foil for the delivery of therapeutic cargos
WO2022055779A1 (en) * 2020-09-09 2022-03-17 Amgen Inc. Swallowable drug delivery devices
US20230338719A1 (en) * 2020-11-02 2023-10-26 Novo Nordisk A/S Substance delivering capsule
CN116897065B (zh) * 2021-03-05 2025-10-14 Bi生物技术有限公司 口服型物质传递装置
CA3252809A1 (en) * 2022-02-21 2023-08-24 Rani Therapeutics, Llc DEVICES THAT CAN BE INGESTED FOR THE PURPOSE OF ADMINISTRATING A FLUID PREPARATION INTO A GASTROINTESTINAL TRACT
CA3252806A1 (en) * 2022-02-21 2023-08-24 Rani Therapeutics, Llc DEVICES, ASSEMBLIES AND METHODS FOR ADMINISTRATING A FLUID PREPARATION INTO A DIGESTIVE TRACT
US20260091210A1 (en) * 2024-10-01 2026-04-02 Alma Therapeutics Ltd. Expandable drug delivery device with enhanced needle penetration pressure

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2860501Y (zh) * 2005-03-10 2007-01-24 李华 一次性注射器
WO2011079302A2 (en) * 2009-12-24 2011-06-30 Incube Labs, Llc Swallowable drug delivery device and methods of drug delivery
WO2013003487A1 (en) * 2011-06-29 2013-01-03 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5125414A (en) * 1990-01-16 1992-06-30 Dysarz Edward D Trap in barrel one handed retracted blood sampling device
US5217449A (en) * 1990-12-11 1993-06-08 Miyarisan Kabushiki Kaisha Medical capsule and apparatus for activating the same
US5279607A (en) * 1991-05-30 1994-01-18 The State University Of New York Telemetry capsule and process
AU6893898A (en) * 1997-04-10 1998-10-30 Johns Hopkins University, The Gaz syringe and package therefor
GB9930000D0 (en) * 1999-12-21 2000-02-09 Phaeton Research Ltd An ingestible device
CA2444377C (en) * 2001-04-13 2014-09-02 Paul G. Alchas Method of intradermally injecting substances
US7160258B2 (en) * 2001-06-26 2007-01-09 Entrack, Inc. Capsule and method for treating or diagnosing the intestinal tract
US20050058701A1 (en) * 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
AU2004208580A1 (en) * 2003-01-29 2004-08-12 E-Pill Pharma Ltd. Active drug delivery in the gastrointestinal tract
WO2006126653A1 (ja) * 2005-05-27 2006-11-30 Olympus Corporation 被検体内導入装置
JP4402648B2 (ja) * 2005-12-16 2010-01-20 オリンパス株式会社 被検体内導入装置
WO2010045477A2 (en) * 2008-10-16 2010-04-22 Obalon Therapeutics, Inc. Intragastric volume-occupying device and method for fabricating same
US8721620B2 (en) * 2009-12-24 2014-05-13 Rani Therapeutics, Llc Swallowable drug delivery device and methods of drug delivery
US8734429B2 (en) * 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
ES2773115T3 (es) * 2011-06-29 2020-07-09 Rani Therapeutics Llc Preparados de agentes terapéuticos para la administración hacia el interior de una luz del tubo intestinal utilizando un dispositivo tragable para la administración de fármacos
EP2968071B1 (en) * 2013-03-15 2021-08-04 Rani Therapeutics, LLC Device for oral delivery of therapeutic compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2860501Y (zh) * 2005-03-10 2007-01-24 李华 一次性注射器
WO2011079302A2 (en) * 2009-12-24 2011-06-30 Incube Labs, Llc Swallowable drug delivery device and methods of drug delivery
WO2013003487A1 (en) * 2011-06-29 2013-01-03 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds

Also Published As

Publication number Publication date
AU2021203778B2 (en) 2023-06-01
JP7434462B2 (ja) 2024-02-20
JP2019069206A (ja) 2019-05-09
JP7808137B2 (ja) 2026-01-28
WO2014159604A1 (en) 2014-10-02
EP2968071B1 (en) 2021-08-04
EP3964190A1 (en) 2022-03-09
AU2021203778A1 (en) 2021-07-22
AU2014240401A1 (en) 2015-09-10
JP2021020110A (ja) 2021-02-18
CN105263461A (zh) 2016-01-20
AU2019201008A1 (en) 2019-03-07
JP2016511124A (ja) 2016-04-14
JP6796484B2 (ja) 2020-12-09
CA3104670A1 (en) 2014-10-02
CA3104670C (en) 2024-10-08
EP2968071A1 (en) 2016-01-20
CA2901923A1 (en) 2014-10-02
EP2968071A4 (en) 2016-10-05
CA3240667A1 (en) 2014-10-02
PT2968071T (pt) 2021-11-12
JP2024036622A (ja) 2024-03-15
AU2023222952B2 (en) 2025-06-05
PL2968071T3 (pl) 2021-12-20
CA2901923C (en) 2021-12-07
AU2019201008B2 (en) 2021-03-25
DK2968071T3 (da) 2021-11-08
AU2014240401B2 (en) 2018-11-15
JP2022162094A (ja) 2022-10-21
ES2897795T3 (es) 2022-03-02
AU2023222952A1 (en) 2023-09-21

Similar Documents

Publication Publication Date Title
JP7808137B2 (ja) 治療化合物の経口送達のためのデバイス
US20250135107A1 (en) Device, system and methods for the oral delivery of therapeutic compounds
AU2020200413B2 (en) Device, system and methods for the oral delivery of therapeutic compounds
JP2016511124A5 (https=)

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant