CA2901923C - Device, system and methods for the oral delivery of therapeutic compounds - Google Patents

Device, system and methods for the oral delivery of therapeutic compounds Download PDF

Info

Publication number
CA2901923C
CA2901923C CA2901923A CA2901923A CA2901923C CA 2901923 C CA2901923 C CA 2901923C CA 2901923 A CA2901923 A CA 2901923A CA 2901923 A CA2901923 A CA 2901923A CA 2901923 C CA2901923 C CA 2901923C
Authority
CA
Canada
Prior art keywords
piston
capsule
balloon
wall
tissue penetrating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2901923A
Other languages
English (en)
French (fr)
Other versions
CA2901923A1 (en
Inventor
Mir Imran
Peter Herrmann
Baber Syed
Timothy H. Williams
Chang JIN ONG
Greg Method
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rani Therapeutics LLC
Original Assignee
Rani Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/837,025 external-priority patent/US8734429B2/en
Application filed by Rani Therapeutics LLC filed Critical Rani Therapeutics LLC
Priority to CA3104670A priority Critical patent/CA3104670C/en
Publication of CA2901923A1 publication Critical patent/CA2901923A1/en
Application granted granted Critical
Publication of CA2901923C publication Critical patent/CA2901923C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CA2901923A 2013-03-15 2014-03-12 Device, system and methods for the oral delivery of therapeutic compounds Active CA2901923C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3104670A CA3104670C (en) 2013-03-15 2014-03-12 DEVICE FOR THE ORAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/837,025 2013-03-15
US13/837,025 US8734429B2 (en) 2010-12-23 2013-03-15 Device, system and methods for the oral delivery of therapeutic compounds
PCT/US2014/024385 WO2014159604A1 (en) 2013-03-15 2014-03-12 Device for oral delivery of therapeutic compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3104670A Division CA3104670C (en) 2013-03-15 2014-03-12 DEVICE FOR THE ORAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS

Publications (2)

Publication Number Publication Date
CA2901923A1 CA2901923A1 (en) 2014-10-02
CA2901923C true CA2901923C (en) 2021-12-07

Family

ID=51625211

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2901923A Active CA2901923C (en) 2013-03-15 2014-03-12 Device, system and methods for the oral delivery of therapeutic compounds
CA3240667A Pending CA3240667A1 (en) 2013-03-15 2014-03-12 Device for oral delivery of therapeutic compounds
CA3104670A Active CA3104670C (en) 2013-03-15 2014-03-12 DEVICE FOR THE ORAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA3240667A Pending CA3240667A1 (en) 2013-03-15 2014-03-12 Device for oral delivery of therapeutic compounds
CA3104670A Active CA3104670C (en) 2013-03-15 2014-03-12 DEVICE FOR THE ORAL ADMINISTRATION OF THERAPEUTIC COMPOUNDS

Country Status (10)

Country Link
EP (2) EP2968071B1 (https=)
JP (5) JP6796484B2 (https=)
CN (1) CN105263461B (https=)
AU (4) AU2014240401B2 (https=)
CA (3) CA2901923C (https=)
DK (1) DK2968071T3 (https=)
ES (1) ES2897795T3 (https=)
PL (1) PL2968071T3 (https=)
PT (1) PT2968071T (https=)
WO (1) WO2014159604A1 (https=)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8682440B2 (en) 2009-08-03 2014-03-25 Incube Labs, Llc Swallowable capsule and method for stimulating incretin production within the intestinal tract
US8721620B2 (en) 2009-12-24 2014-05-13 Rani Therapeutics, Llc Swallowable drug delivery device and methods of drug delivery
US9402807B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8809269B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9861683B2 (en) 2010-12-23 2018-01-09 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9259386B2 (en) 2010-12-23 2016-02-16 Rani Therapeutics, Llc Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9284367B2 (en) 2010-12-23 2016-03-15 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9283179B2 (en) 2010-12-23 2016-03-15 Rani Therapeutics, Llc GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8980822B2 (en) 2010-12-23 2015-03-17 Rani Therapeutics, Llc Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8846040B2 (en) 2010-12-23 2014-09-30 Rani Therapeutics, Llc Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9415004B2 (en) 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9629799B2 (en) 2010-12-23 2017-04-25 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8969293B2 (en) 2010-12-23 2015-03-03 Rani Therapeutics, Llc Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8734429B2 (en) 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US9402806B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US10639272B2 (en) 2010-12-23 2020-05-05 Rani Therapeutics, Llc Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device
EP2968071B1 (en) * 2013-03-15 2021-08-04 Rani Therapeutics, LLC Device for oral delivery of therapeutic compounds
US10220003B2 (en) * 2016-03-09 2019-03-05 Incube Labs, Llc Methods and articles for delivering viable cells into solid tissue
KR20230042759A (ko) * 2016-09-09 2023-03-29 비오라 쎄라퓨틱스, 인크. 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
WO2018213579A1 (en) * 2017-05-17 2018-11-22 Massachusetts Institute Of Technology Self-actuating articles
US10675248B2 (en) * 2018-08-14 2020-06-09 Alma Therapeutics Ltd. Expandable pill
US12128133B2 (en) 2018-09-25 2024-10-29 Rani Therapeutics, Llc Ingestible device with expandable enclosure
CN109621169B (zh) * 2019-01-09 2021-06-08 李红岩 一种产科观察治疗仪
JP7420819B2 (ja) * 2019-02-01 2024-01-23 ノボ・ノルデイスク・エー／エス 作動機構を有する医療デバイス
AU2020360407B2 (en) * 2019-10-01 2026-04-09 Rani Therapeutics, Llc Self-sizing device for delivering a formulation to a lumen wall
WO2021146296A1 (en) * 2020-01-14 2021-07-22 Rani Therapeutics, Llc Swallowable devices for drug delivery in an intestinal tract
WO2021198353A1 (en) * 2020-03-31 2021-10-07 Danmarks Tekniske Universitet A flexible foil for the delivery of therapeutic cargos
WO2022055779A1 (en) * 2020-09-09 2022-03-17 Amgen Inc. Swallowable drug delivery devices
US20230338719A1 (en) * 2020-11-02 2023-10-26 Novo Nordisk A/S Substance delivering capsule
CN116897065B (zh) * 2021-03-05 2025-10-14 Bi生物技术有限公司 口服型物质传递装置
CA3252809A1 (en) * 2022-02-21 2023-08-24 Rani Therapeutics, Llc DEVICES THAT CAN BE INGESTED FOR THE PURPOSE OF ADMINISTRATING A FLUID PREPARATION INTO A GASTROINTESTINAL TRACT
CA3252806A1 (en) * 2022-02-21 2023-08-24 Rani Therapeutics, Llc DEVICES, ASSEMBLIES AND METHODS FOR ADMINISTRATING A FLUID PREPARATION INTO A DIGESTIVE TRACT
US20260091210A1 (en) * 2024-10-01 2026-04-02 Alma Therapeutics Ltd. Expandable drug delivery device with enhanced needle penetration pressure

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5125414A (en) * 1990-01-16 1992-06-30 Dysarz Edward D Trap in barrel one handed retracted blood sampling device
US5217449A (en) * 1990-12-11 1993-06-08 Miyarisan Kabushiki Kaisha Medical capsule and apparatus for activating the same
US5279607A (en) * 1991-05-30 1994-01-18 The State University Of New York Telemetry capsule and process
AU6893898A (en) * 1997-04-10 1998-10-30 Johns Hopkins University, The Gaz syringe and package therefor
GB9930000D0 (en) * 1999-12-21 2000-02-09 Phaeton Research Ltd An ingestible device
CA2444377C (en) * 2001-04-13 2014-09-02 Paul G. Alchas Method of intradermally injecting substances
US7160258B2 (en) * 2001-06-26 2007-01-09 Entrack, Inc. Capsule and method for treating or diagnosing the intestinal tract
US20050058701A1 (en) * 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
AU2004208580A1 (en) * 2003-01-29 2004-08-12 E-Pill Pharma Ltd. Active drug delivery in the gastrointestinal tract
CN2860501Y (zh) * 2005-03-10 2007-01-24 李华 一次性注射器
WO2006126653A1 (ja) * 2005-05-27 2006-11-30 Olympus Corporation 被検体内導入装置
JP4402648B2 (ja) * 2005-12-16 2010-01-20 オリンパス株式会社 被検体内導入装置
WO2010045477A2 (en) * 2008-10-16 2010-04-22 Obalon Therapeutics, Inc. Intragastric volume-occupying device and method for fabricating same
US8721620B2 (en) * 2009-12-24 2014-05-13 Rani Therapeutics, Llc Swallowable drug delivery device and methods of drug delivery
CA2785168C (en) * 2009-12-24 2018-04-17 Incube Labs, Llc Swallowable drug delivery device and methods of drug delivery
US8734429B2 (en) * 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
ES2773115T3 (es) * 2011-06-29 2020-07-09 Rani Therapeutics Llc Preparados de agentes terapéuticos para la administración hacia el interior de una luz del tubo intestinal utilizando un dispositivo tragable para la administración de fármacos
PT3653223T (pt) * 2011-06-29 2021-12-06 Rani Therapeutics Llc Dispositivo para a entrega oral de compostos terapêuticos
EP2968071B1 (en) * 2013-03-15 2021-08-04 Rani Therapeutics, LLC Device for oral delivery of therapeutic compounds

Also Published As

Publication number Publication date
AU2021203778B2 (en) 2023-06-01
JP7434462B2 (ja) 2024-02-20
JP2019069206A (ja) 2019-05-09
JP7808137B2 (ja) 2026-01-28
WO2014159604A1 (en) 2014-10-02
EP2968071B1 (en) 2021-08-04
EP3964190A1 (en) 2022-03-09
AU2021203778A1 (en) 2021-07-22
AU2014240401A1 (en) 2015-09-10
JP2021020110A (ja) 2021-02-18
CN105263461A (zh) 2016-01-20
AU2019201008A1 (en) 2019-03-07
JP2016511124A (ja) 2016-04-14
CN105263461B (zh) 2019-09-10
JP6796484B2 (ja) 2020-12-09
CA3104670A1 (en) 2014-10-02
CA3104670C (en) 2024-10-08
EP2968071A1 (en) 2016-01-20
CA2901923A1 (en) 2014-10-02
EP2968071A4 (en) 2016-10-05
CA3240667A1 (en) 2014-10-02
PT2968071T (pt) 2021-11-12
JP2024036622A (ja) 2024-03-15
AU2023222952B2 (en) 2025-06-05
PL2968071T3 (pl) 2021-12-20
AU2019201008B2 (en) 2021-03-25
DK2968071T3 (da) 2021-11-08
AU2014240401B2 (en) 2018-11-15
JP2022162094A (ja) 2022-10-21
ES2897795T3 (es) 2022-03-02
AU2023222952A1 (en) 2023-09-21

Similar Documents

Publication Publication Date Title
AU2023222952B2 (en) Device for oral delivery of therapeutic compounds
US12263325B2 (en) Device, system and methods for the oral delivery of therapeutic compounds
AU2020294353B2 (en) Device, system and methods for the oral delivery of therapeutic compounds
US9149617B2 (en) Device, system and methods for the oral delivery of therapeutic compounds
HK40071470A (en) Device for oral delivery of therapeutic compounds
HK40072041A (en) Device for the oral delivery of therapeutic compounds

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20190306

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 11TH ANNIV.) - SMALL

Year of fee payment: 11

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20241212

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20241212

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 12TH ANNIV.) - SMALL

Year of fee payment: 12

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20251202

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20251202