CN105250887A - Traditional Chinese medicine electuary for treatment and nursing of ICU myasthenia gravis and preparation method - Google Patents

Traditional Chinese medicine electuary for treatment and nursing of ICU myasthenia gravis and preparation method Download PDF

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CN105250887A
CN105250887A CN201510852960.5A CN201510852960A CN105250887A CN 105250887 A CN105250887 A CN 105250887A CN 201510852960 A CN201510852960 A CN 201510852960A CN 105250887 A CN105250887 A CN 105250887A
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radix
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fructus
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刘艳丽
李春雷
韩菲
李芳芳
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Abstract

The invention discloses traditional Chinese medicine electuary for treatment and nursing of ICU myasthenia gravis and a preparation method and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine electuary is prepared from ficus beecheyana hook, Chinese dates, uncaria roots, mucuna sempervirens, triple shot range, milkvetch roots, ventilago leiocarpa benth, silverweed cinquefoil roots, wild black soybeans, lotus leaves, tuber fleeceflower stems, liquorice, akebiaquinata roots, pawpaws, cynachum uilfordii hemsl, radix paeoniae alba, glossy privet fruits, radix angelicae pubescentis, rattlesnake plantain, Sichuan cinnamon, cortex acanthopanacis, fructus amomi, gynostemma pentaphylla and antelope's horns. The medicine properties of the selected medicinal materials are adaptive and complementary, the medicine is applied pointing to symptoms according to pathogenesis, the effects of tonifying the liver and kidney, tonifying the spleen and raising yang, invigorating qi and blood, strengthening tendons and bones, relaxing tendons and activating collaterals and promoting qi to activate blood are achieved, the absorption effect is good, the curative effect is remarkable, no toxic or side effect or clinical adverse reaction is generated, and the traditional Chinese medicine electuary is high in cure rate for myasthenia gravis through clinical verification.

Description

For the treatment of ICU myasthenia gravis and the instant particles as Chinese medicine of nursing and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to for the treatment of ICU myasthenia gravis and the instant particles as Chinese medicine of nursing and preparation method.
Background technology
Myasthenia gravis (MG) is a kind of autoimmune disease caused by neuromuscular junction propagation function obstacle, and clinical main manifestations is part or whole body skeletal muscle weakness and fatiguability, exacerbation of symptoms after movable, and after having a rest, symptom alleviates.Prevalence is 77 ~ 15,0/1,000,000, and annual morbidity is 4 ~ 1,1/1,000,000.This disease women than men is more common, usually starts between 20 ~ 40 years old, also can occur in any age.Modal symptom is eyelid unable (ptosis), and eye muscle is weak, and this will cause diplopia, and after activity, the special fatiguability of muscle.In the patient suffering from myasthenia gravis, first 40% eye muscle gets involved, and the patient of 85% finally can be had to get involved, and speaks and dysphagia and bilateral upper arm and weakness of the lower extremities are also common symptoms.
Myasthenia gravis is the autoimmune disease of a kind of striped muscle neuromuscular junction point place conductive impairment, with muscle fatiguability weight at light dusk in morning, has a rest or with alleviating as feature after cholinesterase inhibitor, often involving extraocular muscles, masticatory muscles, swallowing flesh and respiratory muscle.At present for the treatment of myasthenia gravis, doctor trained in Western medicine common drug is as anticholinergic class medicine, immunosuppressant, hormone and biological preparation etc., or operative treatment, though energy temporary relief of symptoms, but often cure the symptoms, not the disease, easily repeatedly, long-term taking easily produces dependency and drug resistance, and toxic and side effects is large, loses if long-term and to control or to bad recovery in late period.
Myasthenia gravis belongs to the traditional Chinese medical science " fistula card " category, with blepharoptosis, tetraparesis is unable, light dusk in morning is heavy, gradually increases the weight of or is the disease of feature with dysphagia, dysarthria, and its basic pathogenesis is deficiency of spleen and stomach, therefore control to train spleen the kidney invigorating, benefiting qi and nourishing yin is main, achieve good curative effect, but treatment cycle is longer.The present invention sums up through long-term clinical practice, outside the Pass thinking that primary disease removes and to have with spleen kidney, also in close relations with liver, lid liver governing tendons, kidney governing bones, it is strong that kidney fills then bone, and liver is filled then muscle and is good for, and bends and stretches utilization, all belong to muscle, essence and blood fills Sheng, then muscles and bones is strong, movable normal, and essence and blood loss can not be irrigated and flourishly be supported muscles then to cause flaccidity soft unable; And the spleen being the foundation of acquired constitution, main transporting the lucid yang sending up, it fills at flesh, and spleen loses transporting, and clear sun can not real extremity, then extremity flaccidity soft can not with, upper eye lid eyelid belongs to spleen, and insufficiency of the spleen elevate a turnable ladder is unable, then blepharoptosis ptosis.The present invention, according to the cause of disease, suits the remedy to the case, and has effect of liver and kidney tonifying, spleen invigorating yang invigorating, benefiting vital QI and blood, strengthening the tendons and bones, relaxing muscles and tendons and activating QI and blood in the collateral, promoting flow of QI and blood, fundamentally start with, treat, make the QI and blood of patient more unobstructed, strengthen the immunity of patient body, by long-term treatment, the conductive obstruction of the muscle of patient and neural joint can be allowed to fade away, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to myasthenia gravis cure rate through clinical verification.
Summary of the invention
The invention provides for the treatment of ICU myasthenia gravis and the instant particles as Chinese medicine of nursing and preparation method, there is effect of liver and kidney tonifying, spleen invigorating yang invigorating, benefiting vital QI and blood, strengthening the tendons and bones, relaxing muscles and tendons and activating QI and blood in the collateral, promoting flow of QI and blood, cure the disease and ask source treating both the principal and secondary aspects of a disease, to the myasthenia gravis that a variety of causes causes, all there is good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
For the instant particles as Chinese medicine of ICU myasthenia gravis treatment with nursing, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
For the treatment of ICU myasthenia gravis and the preparation method of the instant particles as Chinese medicine of nursing, comprise following processing step:
(1) Radix Fici beecheyanae, Fructus Jujubae, Radix Uncariae rhynchophyllae, Radix Pedicularis Henryi, Radix potentillae anserinae, Semen glycines sojae, Folium Nelumbinis, Caulis Polygoni Multiflori, Radix Glycyrrhizae, Radix cynanchi wilfordii, river Cortex cinnamomi japonici (Ramulus Cinnamomi), Cortex Acanthopancis, Fructus Amomi, Herb Gynostemmae Pentaphylli are cleaned, dry rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Radix Seu Caulis Mucunae Sempervirentis, Radix seu Caulis Verntilaginis Leiocarpae, Radix Akebiae, Radix Angelicae Pubescentis, Herba goodyearae repentis are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) astragalus mongholicus tablet is added cooked Mel and a little boiled water, mixes thoroughly slightly vexed, put in pot fry to yellow and tack-free time, take out and dry in the air cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(4) put in pot by papaya tablet, fry to micro-Jiao's degree of being with slow fire, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(5) get Radix Paeoniae Alba sheet, spray yellow wine is mixed thoroughly, and after slightly vexed, put with slow fire heating in pot, fried dry, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(6) get clean Fructus Ligustri Lucidi to add yellow wine and mix thoroughly, put in appropriate vessel, airtight, sit in kettle, stewing out of water exhausts to wine, takes out, dry, pulverize and grind into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(7) grind into powder after Cornu Saigae Tataricae being pulverized, cross 100 order dusting covers, obtain fine powder, for subsequent use;
(8) by the thick paste of step (1), step (2) gained, after in step (3), step (4), step (5), step (6), step (7), the fine powder of gained mixes, add adjuvant sucrose and dextrin mix homogeneously makes granule, after drying, granulate, be packaged into the instant particles as Chinese medicine often wrapping 10g.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Fici beecheyanae: sweet in the mouth; Pungent; Warm in nature.Return lung; Spleen; Kidney channel.Replenishing QI to invigorate the spleen; Promoting blood circulation to remove obstruction in the collateral; Expelling wind and removing dampness.Cure mainly overstrain weak; Lack of appetite; Agalactia; Insufficiency of the spleen leucorrhea; Proctoptosis; Menoxenia; Wind syndrome of head pain; Traumatic injury; Rheumatic arthralgia." east, Fujian book on Chinese herbal medicine ": invigorating the spleen and replenishing QI, invigorating the spleen for eliminating dampness, bone and muscle strengthening, detumescence, promoting blood circulation and detoxication.Control the middle deficiency of vital energy weak, QI and blood is on the decline, and extremity are aching and limp, stiffness of the muscle and joint, amenorrhea, galactostasis.
Fructus Jujubae: sweet in the mouth; Temperature.Return spleen; Stomach warp.Tonifying the spleen and stomach; Replenishing QI and blood; Tranquilizing mind; Battalion is adjusted to defend; And the property of medicine.Cure mainly weakness of the spleen and stomach; Insufficiency of vital energy and blood; Anorexia and loose stool; Fatigue and weakness; Palpitation and insomnia; Woman hysteria; Disharmony of nutrient QI with defensive QI." book on Chinese herbal medicine remittance speech ": Shen Shi says, and the sweet profit cream of this medicine coagulates, kind nourishing YIN sun, QI and blood, body fluid, venation, muscle Yu, bone marrow, and all are deficient, without shoulding not it.As imperial Tan Fang controls palpitation with fear palpitation with a distress feeling, dimly forgetful, will meaning stupor, spirit is not kept, or middle gas discord, poor appetite, and hundred body lazynesses are heavy, and muscle is thin, and the card that this belongs to the heart, spleen two hides unit god loss, must control it with Fructus Jujubae.
Radix Uncariae rhynchophyllae: bitter in the mouth; Puckery; Cold in nature.Enter Liver Channel.Relaxing muscles and tendons and activating QI and blood in the collateral; Clearing heat for detumescence.Cure mainly arthragra; Hemiplegia; Epilepsy; Edema; Injury from falling down." conventional Chinese herbal medicine handbook " carries: " control arthragra, rheumatic arthritis, sciatica." modern medicine study shows, Radix Uncariae rhynchophyllae has significant antiinflammatory, antibacterial action.
Radix Seu Caulis Mucunae Sempervirentis: sweet in the mouth, warm in nature.Blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, dredge the meridian passage.For traumatic injury, rheumatalgia, numbness, stimulate the menstrual flow, amenorrhea." classifying herbal ": " control cold chronic infantile convulsion due to dysfunction of the spleen, rheumatic numbness, bones and muscles pain, detumescence."
Radix Pedicularis Henryi: sweet in the mouth; Micro-hardship; Slightly warm in nature.Fill blood; Bone and muscle strengthening; Strengthening the spleen and stomach.Cure mainly dizziness and tinnitus; Palpitation and short breath; Brothers' flaccidity is soft; Bones and muscles pain; Bronchitis; Food stagnation of child; Malnutrition.
The Radix Astragali: sweet in the mouth; Warm in nature.Enter the heart; Lung; Spleen; Kidney channel.Invigorating QI to consolidate the body surface resistance; Diuresis; Expelling pus and toxin by strengthening QI; Promoting tissue regeneration and ulcer healing.Cure mainly cardiopalmus of breathing hard; Asthenia; Weak; Spontaneous perspiration; Night sweat; Chronic diarrhea; Proctoptosis; Body is impractical swollen; Uterine prolapse; Chronic nephritis; Carbuncle difficulty is burst; Or burst do not hold back for a long time." Xinhua's book on Chinese herbal medicine outline " carries: " have the function of invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting." modern medicine study confirms; Radix Astragali main component is Radix Astragali total flavones, Radix Astragali Mongolici total polysaccharide, Radix Astragali total saponins and aminoacid etc.; have diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxidant radical generate and improve the multiple pharmacological effect such as body's immunity; can act on body from many aspects, improves the relevant blood vessel sexually transmitted disease (STD)s such as cardiovascular, cerebrovascular, diabetes, nephropathy and becomes the functions such as the hemodynamics of patient and vascular endothelial cell.
Radix seu Caulis Verntilaginis Leiocarpae: sweet in the mouth; Warm in nature.Return lung; Spleen channel.Fill blood; Bone and muscle strengthening; Relax meridians.Cure mainly deficient qi and blood; Have through uncomfortable; Blood deficiency amenorrhea; Rheumatalgia; Traumatic injury; Lumbar muscle strain." conventional Chinese herbal medicine handbook ": rich in nutrition, relaxing muscles and tendons and activating QI and blood in the collateral.Control deficiency of both QI and blood, menoxenia, bones and muscles pain due to rheumatism, numb limbs and tense tendons, traumatic injury.
Radix potentillae anserinae: sweet in the mouth; Bitter; Cold.Return spleen; Stomach warp.Fill blood, strengthening the spleen and stomach, promoting the production of body fluid to quench thirst, dampness removing.For anemia after being ill, malnutrition, insufficiency of the spleen diarrhoea, rheumatic arthralgia." Chinese herbal medicine is commonly used in Tibet ": " vigorate qi and replenish the blood, controls insufficiency of the spleen diarrhoea, after being ill anemia, malnutrition for invigorating spleen and reinforcing stomach, promoting the production of body fluid to quench thirst." modern study proves: Radix potentillae anserinae contains two kinds of compositions of contraction and relaxing smooth muscle, has certain influence, and have cardiotonic to smooth muscle.
Semen glycines sojae: sweet in the mouth, cold nature.Liver and kidney tonifying, removing toxic substances of dispeling the wind.Cure mainly and cloudy lose blurred vision, lumbago due to renal deficiency, night sweat, bones and muscles pain, puerperal puerperal tetanus, infant malnutrition." book on Chinese herbal medicine converges and says ": " separate interior-heat to quench one's thirst, only night sweat due to yin deficiency."
Folium Nelumbinis: bitter in the mouth is pungent, micro-puckery, cool in nature.GUIXIN, liver, spleen channel.Delicate fragrance rises loose; There is summer heat relieving and dampness eliminating, spleen invigorating yang invigorating, effect of dissipating blood stasis hemostasis.Cure mainly summer-heat excessive thirst, have a headache dizzy, edema, lack of appetite abdominal distention, dysentery, leucorrhea, proctoptosis, spit blood, epistaxis, spitting of blood, has blood in stool, metrorrhagia, post partum longtime lochia, traumatic blood stasis.Modern study result shows, Folium Nelumbinis has effect for reducing blood fat.Nuciferine is the alkaloid extracted in Folium Nelumbinis, the expansible blood vessel of nuciferine, and clearing away summer-heat, has the effect of blood pressure lowering, the good medicine of still fat-reducing simultaneously.
Caulis Polygoni Multiflori: sweet in the mouth; Micro-hardship; Property is put down.Enter the heart; Liver Channel.Tranquilizing by nourishing the heart; Dispel the wind; Dredging collateral.Cure mainly insomnia; Dreaminess; Blood deficiency general pain; Numbness of the skin; Rheumatic arthralgia; Rubella pruritus." decoction pieces is newly joined " carries: " nourishing the liver and kidney, only sweating due to debility, hypnosis of calming the nerves, invigorating middle warmer gas, network of passing through, promoting blood circulation, controls impairment caused by overstrain." modern medicine study confirmation, Caulis Polygoni Multiflori contains emodin, physcione, is synergism with pentobarbital sodium, has significant calmness, syngignoscism.
Radix Glycyrrhizae: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, draft is malicious by every means to separate 1,002, is in harmonious proportion from medicine and gains merit." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have anti-gastric-ulcer, gastritis effect in addition.
Radix Akebiae: bitter in the mouth; Property is put down; Return liver; Kidney channel.Dispelling wind and removing obstruction in the collateral; Inducing diuresis to remove edema; Promoting flow of QI and blood; Invigorating the liver and kidney; Bone and muscle strengthening.Cure mainly rheumatic arthralgia; Traumatic injury; Amenorrhea; Hernia; Painful and swollen testis; Gastral cavity abdominal distention is vexed; Dysuria; Leukorrhagia; Worm venom." Zhejiang conventional medical herbs among the people ": wind-expelling pain-stopping, promoting flow of QI and blood, diuresis is detoxified.
Fructus Chaenomelis: sour in the mouth; Warm in nature.Enter liver; Lung; Kidney; Spleen channel.Relaxing muscles and tendons and activating QI and blood in the collateral; Stomach function regulating removing dampness.Cure mainly rheumatic arthralgia, vague aching of limbs, the contracture of muscle arteries and veins, convulsion of vomiting and diarrhoea, beriberi edema." book on Chinese herbal medicine is just " carries: " treat weakness of the waist and knees, beriberi, tying-in institute is indispensable, the stagnation of QI can and, QI prostration can admittedly.With the flat stomach of energy, therefore except vomiting, cramp caused by acute vomiting and diarrhea, fall expectorant, dry, row water." modern medicine study confirmation, Fructus Chaenomelis is containing carpaine, papain, Chymosin, carotene etc.; And be rich in 17 kinds with upper amino acid and various nutrient elements, have hepatoprotective fall enzyme, antiinflammatory antibacterial, reduce the effects such as blood fat, also have the effect stoping the synthesis of human carcinogen's material nitrosamine.
Radix cynanchi wilfordii: sweet in the mouth; Micro-hardship; Slightly warm in nature; Return spleen; Stomach; Kidney channel.Invigorating the liver and kidney; Bone and muscle strengthening; Strengthening the spleen and stomach; Removing toxic substances.Main Liver and kidney two is empty; Feel dizzy; Insomnia forgetfulness; Early whitening of beard and hair; Sexual impotence; Seminal emission; Soreness of the waist and knees; Spleen insufficiency; Distension and fullness in the abdomen; Inhibited sexual desire; Have loose bowels; Puerperal, breast was few; Lymphogranuloma inguinale sore." Shaanxi Chinese herbal medicine ": nourishing YIN and benefiting blood, spleen invigorating is pleasant, sedation-analgesia, lactogenic.To treat for stomachache abdominal distention, asthenia, lumbago due to renal deficiency, sexual impotence, the abdominal lump of chilren, leucorrhea, hypogalactia.
The Radix Paeoniae Alba: bitter in the mouth; Property is put down.Enter liver; Spleen channel.Nourishing blood to suppress the hyperactive liver, pain relieving in slow; Yin fluid astringing receives antiperspirant.Cure mainly the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency." not Lu " carries: " clear and coherent blood vessels, in slow, dispelling malignant blood, expelling extravasated blood, anhydrate gas, sharp bladder, intestine and small intestine, subduing inflammation, row cold and heat when controlling, and attacked by pestiferous factors is suffered from abdominal pain, lumbago." modern medicine study confirms; Radix Paeoniae Alba energy immunity moderation; strengthen macrophage and leukocytic phagocytic function; regulate the immunologic function of T lymphocyte and body fluid; protect the liver, spasmolytic, analgesia, calmness, anti-cool, cooling effect; have inhibitory action to smooth muscle in addition, strengthen the effect of anoxia enduring, antioxidation and resisting fatigue.
Fructus Ligustri Lucidi: bitter in the mouth; Cool in nature.Return liver; Kidney channel.Tonifying liver kidney yin, crow must improving eyesight.Cure mainly the hepatic and renal YIN deficiency; Soreness of waist tinnitus; Early whitening of beard and hair; Unseeing; Fever due to yin deficiency; Gastropathy and gout and hyperuricemia." book on Chinese herbal medicine is new again ": replenishing YIN to strengthen the kidney, QI invigorating soothing liver-QI.Control lumbago and skelalgia, stimulate the menstrual flow and blood.Modern medicine study proves, Fructus Ligustri Lucidi is containing oleanolic acid, mannitic acid, Fructus Vitis viniferae acid, Palmic acid, stearic acid, oleic acid, linoleic acid etc.Fructus Ligustri Lucidi can improve peripheral leukocytes, strengthen reticuloendothelial system phagocytic activity, has the effect strengthening cellular immunization and humoral immunization.There is blood fat reducing again, study of anti-atherogenic effect.Rising effect is had to the leukopenia caused because of chemotherapy or radiotherapy.The growth of some transplanted tumor of animal can be suppressed.There are heart tonifying, diuresis and hepatoprotective effect; And have cough-relieving, cathartic, the effect such as antibacterial.
Radix Angelicae Pubescentis: acrid in the mouth; Bitter; Warm in nature.Enter liver; Kidney channel.Expelling wind and removing dampness; Relaxing muscles and tendons and activating QI and blood in the collateral; Regulating blood flow to alleviate pains.Cure mainly rheumatalgia; Soreness of waist and knee joint; Extremity flaccidity syndrome and arthralgia syndrome; Lumbar muscle strain; The arthroncus of knee; Brothers sprain and swell and ache; Fracture; Wind syndrome of head; Headache; Toothache." book on Chinese herbal medicine is newly organized " carries: " sweet in the mouth is pungent, warm in nature, can rise and can fall, the YIN aspect of YANG, nontoxic.Though there is upper purgation to divide, enrich blood then one.Enter the heart, spleen, liver three are dirty, but its property is very dynamic, then QI invigorating in the Qi-tonifying drug entered, then enriches blood in the hematonic entered, without determining merit also." modern medicine study confirms; Radix Angelicae Pubescentis has analgesia, cooling, extends the effect of anaesthetized with pentobarbital phase; and can suppress the mobility that metamfetamine strengthens; promote protein synthesis; have facilitation to the synthesis of DNA, RNA; can reduce thymol turbidity, increase the ability of erythrocyte transport oxygen, inhibited oxidation react and radical reaction to the infringement organized.
Herba goodyearae repentis: sweet in the mouth; Pungent; Property is put down.Nourishing the lung to arrest cough; Tonify Qi of the kidney; Promoting flow of QI and blood; Subduing swelling and detoxicating.Cure mainly pulmonary tuberculosis cough; Tracheitis; Dizzy weak; Neurasthenia; Sexual impotence; Traumatic injury; Arthralgia; Laryngopharynx swelling and pain; Furuncle; Scrofula; Venom." Chinese herbal medicine is commonly used in Tibet ": " hard masses softening and resolving.Control scrofula."
River Cortex cinnamomi japonici (Ramulus Cinnamomi): acrid in the mouth; Sweet; Warm in nature.Dispelling cold by warming the meridian; Promoting flow of QI and blood; Pain relieving.Cure mainly: anemofrigid cold; Stomachache with cool feeling; Dysmenorrhea; Fengshi Guanjie pain; Traumatic injury; Fracture.
Cortex Acanthopancis: acrid in the mouth, hardship, warm in nature.Return liver, kidney channel.Wind-damp dispelling; Invigorating the liver and kidney; Bone and muscle strengthening; To invigorate blood circulation arteries and veins.Main anemofrigid-damp arthralgia; Lumbocrural pain; Muscles and bones flaccidity is soft; Children's's walking retardation in children; Body void is frail; Traumatic injury; Fracture; Edema; Foot gas; Uncontrolled urination is itched." book on Chinese herbal medicine is new again ": eliminating phlegm and removing dampness, supports kidney benefit essence, removes emaciation due to emotional upset water, and reason beriberi lumbago, controls all poison of skin ulcer scabies.Modern study proves, this product has the effects such as antitumor, resisting fatigue, reduction whole blood viscosity, atherosclerosis formation.
Fructus Amomi: acrid in the mouth; Warm in nature.Enter spleen; Stomach; Kidney channel.Removing dampness is whetted the appetite; Promoting the circulation of QI to alleviate the stagnation in middle-JIAO; Warming the spleen; Antidiarrheal; Antiabortive.Cure mainly retention of damp leading to blockage of QI; Abdominal distention; Anorexia; Nausea and vomiting; Stomachache is had loose bowels; Pregnancy reactions; Frequent fetal movement." detailed outline " carries: " tonifying the lung is amusing, nourishing the stomach kidney tonifying, reason vigour, dispelling stagnant Qi, dispelling cold fluid-retention and abdominal distension, dysphagic vomiting, only woman's metrorrhagia, except throat ability to speak superficial heat, changes copper gagger and chokes." modern medicine study confirmation, Fructus Amomi can strengthen intestinal contraction, has inhibitory action time heavy dose of to intestinal tube; performance tension force reduces, and partially or completely antagonism acetylcholine promotes intestinal movement; obvious anticoagulant, obviously antagonism collagen and adrenergic fall out effect.
Herb Gynostemmae Pentaphylli: bitter in the mouth; Micro-sweet; Cool in nature.Return lung; Spleen; Kidney channel.To nourish heart spleen invigorating, QI invigorating and blood regulating, heat-clearing and toxic substances removing, blood stasis dispelling of eliminating the phlegm.Cure mainly: body void is weak; Nephrasthenia emission; Leukopenia; Hyperlipemia; Viral hepatitis; Chronic gastroenteritis; Chronic tracheitis.Record in " the little book series of bright clear TCM Clinical ": Herb Gynostemmae Pentaphylli boosting qi and nourishing yin, removing heat from the lung and dissipating phlegm, tranquilizing by nourishing the heart, spermatogenesis controlling nocturnal emission with astringent drugs.Modern medicine study finds, Herb Gynostemmae Pentaphylli principle active component is polysaccharide, flavonoid, saponins and microelement kind, its effect mainly promotes body fat class substance metabolism, nutrition human body cell, there is good detoxicating, relieving inflammation effect simultaneously, be widely used in hyperlipidemia, fatty liver, obesity, constipation, insomnia, hepatitis B, the treatment of chronic airway inflammation (pharyngolaryngitis, gastroenteritis etc.) and health care.
Cornu Saigae Tataricae: salty in the mouth; Cold in nature.Return liver; Heart channel.Suppressing the hyperactive liver to relieve the wind syndrome; Liver heat removing and eyesight improving; Removing pathogenic heat from blood and toxic substance from the body.Cure mainly liver-wind stirring up internally infantile convulsion to twitch; The contracture of muscle arteries and veins; Liver-yang headache is dizzy; Liver-fire conjunctival congestion and swelling pain and heat in blood hemorrhage; Epidemic febrile disease sends out speckle; Carbuncle sore tumefacting virus." book on Chinese herbal medicine is new again ": centering god, only night sweat, consumer edema, blood stasis removing blood, tissue regeneration promoting blood, the pathogenic fire reducing therapeutic method to keep the adverse QI flowing downwards, relieving restlessness of quenching the thirst.Modern medicine study proves: Cornu Saigae Tataricae has calmness, analgesia, antipyretic and anticonvulsant action, and has certain effect to blood circulation tool.
The present invention compared with prior art, has following beneficial effect:
The present invention selects the property of medicine of medical material suitable mutually auxiliary mutually, suit the remedy to the case for the cause of disease, there is effect of liver and kidney tonifying, spleen invigorating yang invigorating, benefiting vital QI and blood, strengthening the tendons and bones, relaxing muscles and tendons and activating QI and blood in the collateral, promoting flow of QI and blood, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to myasthenia gravis cure rate through clinical verification.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The processing step of process for preparing medicine of the present invention is:
(1) Radix Fici beecheyanae, Fructus Jujubae, Radix Uncariae rhynchophyllae, Radix Pedicularis Henryi, Radix potentillae anserinae, Semen glycines sojae, Folium Nelumbinis, Caulis Polygoni Multiflori, Radix Glycyrrhizae, Radix cynanchi wilfordii, river Cortex cinnamomi japonici (Ramulus Cinnamomi), Cortex Acanthopancis, Fructus Amomi, Herb Gynostemmae Pentaphylli are cleaned, dry rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Radix Seu Caulis Mucunae Sempervirentis, Radix seu Caulis Verntilaginis Leiocarpae, Radix Akebiae, Radix Angelicae Pubescentis, Herba goodyearae repentis are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) astragalus mongholicus tablet is added cooked Mel and a little boiled water, mixes thoroughly slightly vexed, put in pot fry to yellow and tack-free time, take out and dry in the air cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(4) put in pot by papaya tablet, fry to micro-Jiao's degree of being with slow fire, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(5) get Radix Paeoniae Alba sheet, spray yellow wine is mixed thoroughly, and after slightly vexed, put with slow fire heating in pot, fried dry, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(6) get clean Fructus Ligustri Lucidi to add yellow wine and mix thoroughly, put in appropriate vessel, airtight, sit in kettle, stewing out of water exhausts to wine, takes out, dry, pulverize and grind into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(7) grind into powder after Cornu Saigae Tataricae being pulverized, cross 100 order dusting covers, obtain fine powder, for subsequent use;
(8) by the thick paste of step (1), step (2) gained, after in step (3), step (4), step (5), step (6), step (7), the fine powder of gained mixes, add adjuvant sucrose and dextrin mix homogeneously makes granule, after drying, granulate, be packaged into the instant particles as Chinese medicine often wrapping 10g.
Usage and dosage: every day wraps for 3 times each 1, and half an hour ante cibum takes after mixing it with water with boiled water, 30 days is 1 course for the treatment of.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection
The routine clinical observation of Patients With Myasthenia Gravis 80 selecting my institute to make a definite diagnosis, increases for having thymoma or thymus and need go the Patients With Myasthenia Gravis of operation and be not selected into case.Patient is divided into two groups at random.Treatment group 40 example, wherein male 13 example, women 27 example, 11 ~ 64 years old age, 27.6 years old mean age, the shortest person of the course of disease 1 month, most elder 3 years, average 0.8 year.Matched group 40 example, wherein male 14 example, women 26 example, 12 ~ 63 years old age, 26.5 years old mean age, the shortest person of the course of disease 1 month, most elder 3 years, average 0.7 year.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.
2, treatment group patient takes medicine of the present invention, and every day wraps for 3 times each 1, and half an hour ante cibum takes after mixing it with water with boiled water, within 30 days, is 1 course for the treatment of, takes 1-3 the course for the treatment of.
Matched group patient, according to the different patient's condition of the myasthenia gravis diagnosed out, selects the alone or use in conjunction of the Western medicine such as immunosuppressant and anticholinergic medicine as required, and drug dose is according to conditions of patients and the different symptomatic treatment of body weight.
3, efficacy determination:
(1) fully recover: clinical symptoms and sign disappear, can orthobiosis, study and work, the medicines of all treatments of stopping using, follow up a case by regular visits to more than 1 year without recurrence.
(2) be almost recovered: clinical symptoms and sign take an evident turn for the better, life of taking care of oneself, adhere to that study maybe can complete light work, the dose of medicine reduces more than 1/2, lasts more than 1 month without recurrence.
(3) take a turn for the better: clinical symptoms and sign take a favorable turn, and self care ability is improved, the consumption of medicine reduces more than 1/4, lasts more than 1 month without recurrence.
(4) invalid: clinical symptoms and sign are with treating front no significant difference.
4, result
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group, illustrate and use the curative effect of instant particles as Chinese medicine of the present invention to treat significantly better than use Western medicine, and use instant particles as Chinese medicine of the present invention to have no side effect and clinical adverse, therefore can be used for the treatment of Patients With Myasthenia Gravis.
Model case is illustrated:
1, Lee's ××, man, 45 years old, there is left side blepharoptosis in this patient's WA every day, and left eye occurred ghost image in right tiltedly rear at leisure afterwards, carry out institute's inquiring, be diagnosed as myasthenia gravis, after taking 1 course for the treatment of of instant particles as Chinese medicine of the present invention, above-mentioned symptom disappears completely, follow up a case by regular visits to and do not recur for 1 year, fully recover.
2, Cai's ××, female, 59 years old, patient's limbs fatigue, masticatory atonia, carrys out institute's inquiring, is diagnosed as myasthenia gravis, after taking 1 course for the treatment of of instant particles as Chinese medicine of the present invention, above-mentioned symptom obviously alleviates, and follow the doctor's advice after continuing to take 2 courses for the treatment of of instant particles as Chinese medicine of the present invention, above-mentioned symptom disappears completely, follow up a case by regular visits to and do not recur for 1 year, fully recover.
3, yellow ××, female, 14 years old, this patient's weakness of the lower extremities, namely movable one feel tired, blepharoptosis after the meeting, head can not lifted, and carrys out institute's inquiring, is diagnosed as myasthenia gravis, after taking 2 courses for the treatment of of instant particles as Chinese medicine of the present invention, above-mentioned symptom obviously alleviates, and follow the doctor's advice after continuing to take 1 course for the treatment of of instant particles as Chinese medicine of the present invention, above-mentioned symptom disappears completely, follow up a case by regular visits to and do not recur for 1 year, fully recover.
4, Lee's ××, man, 27 years old, because working overtime excessively, there is right side blepharoptosis in this patient after tired, diplopia early weighs light evening, tired postemphasis phenomenon is alleviated after rest, rear because of flu aggravation, there is limbs fatigue, soreness of the waist and knees, the unable symptom lifted of arm, carrys out institute's inquiring, is diagnosed as myasthenia gravis, after taking 3 courses for the treatment of of instant particles as Chinese medicine of the present invention, above-mentioned symptom disappears substantially, and follow the doctor's advice after continuing to take 1 course for the treatment of of instant particles as Chinese medicine of the present invention, above-mentioned symptom disappears completely, follow up a case by regular visits to and do not recur for 1 year, fully recover.
Myasthenia gravis is the disease of a not only difficult but also easy treatment, and easily refer to symptom comparatively easily " healing ", after drug withdrawal that refractory refers to " healing ", very easily recur, relapse rate is higher.This electuary be through long-term clinical practice sum up configuration form, suit the remedy to the case according to the cause of disease, side in the Radix Astragali, Radix Fici beecheyanae, Herb Gynostemmae Pentaphylli, Fructus Amomi, Folium Nelumbinis can invigorating the spleen and replenishing QI, spleen invigorating yang invigorating; Fructus Jujubae, Radix potentillae anserinae, Radix seu Caulis Verntilaginis Leiocarpae, Radix Pedicularis Henryi can invigorating spleen and reinforcing stomach, benefiting vital QI and blood; Radix cynanchi wilfordii, Fructus Ligustri Lucidi, Semen glycines sojae, Cortex Acanthopancis can invigorating the liver and kidney, bone and muscle strengthening; The Radix Paeoniae Alba can nourishing blood to suppress the hyperactive liver, clear and coherent blood vessels; Cornu Saigae Tataricae can suppressing the hyperactive liver to relieve the wind syndrome; Radix Uncariae rhynchophyllae, Radix Angelicae Pubescentis, Fructus Chaenomelis can relaxing muscles and tendons and activating QI and blood in the collateral; Radix Seu Caulis Mucunae Sempervirentis, Radix Akebiae, Herba goodyearae repentis, river Cortex cinnamomi japonici (Ramulus Cinnamomi) can blood circulation promoting and blood stasis dispelling, promoting flow of QI and blood, dispelling wind and removing obstruction in the collateral; Caulis Polygoni Multiflori can tranquilizing by nourishing the heart; Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription; All medicines share, effect of liver and kidney tonifying, spleen invigorating yang invigorating, benefiting vital QI and blood, strengthening the tendons and bones, relaxing muscles and tendons and activating QI and blood in the collateral, promoting flow of QI and blood can be played altogether, fundamentally start with and treat, QI and blood and internal organs are also mended, make the QI and blood of patient more unobstructed, regulate function, strengthen the immunity of patient body, by long-term treatment, the conductive obstruction of the muscle of patient and neural joint can be allowed to fade away, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to myasthenia gravis cure rate through clinical verification.

Claims (4)

1. for the treatment of ICU myasthenia gravis and the instant particles as Chinese medicine of nursing, it is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
Radix Fici beecheyanae 66 ~ 85 portions of Fructus Jujubaes 63 ~ 82 parts of Radix Uncariae rhynchophyllaes 60 ~ 80 parts of Radix Seu Caulis Mucunae Sempervirentis 57 ~ 77 parts
Radix Pedicularis Henryi 54 ~ 74 parts of Radixs Astragali 51 ~ 70 parts of Radix seu Caulis Verntilaginis Leiocarpae 48 ~ 67 parts of Radix potentillae anserinae 45 ~ 64 parts
33 ~ 52 parts, Semen glycines sojae 42 ~ 61 parts of Folium Nelumbinis 39 ~ 58 parts of Caulis Polygoni Multiflori 36 ~ 55 portions of Radix Glycyrrhizaes
Radix Akebiae 30 ~ 48 portions of Fructus Chaenomeliss 27 ~ 45 parts of Radix cynanchi wilfordii 24 ~ 42 portions of Radix Paeoniae Albas 21 ~ 38 parts
10 ~ 25 parts, Fructus Ligustri Lucidi 18 ~ 35 parts of Radix Angelicae Pubescentiss 15 ~ 32 parts of Herba goodyearae repentis 12 ~ 28 parts of river Cortex cinnamomi japonici (Ramulus Cinnamomi)s
Cortex Acanthopancis 8 ~ 22 parts of Fructus Amomis 6 ~ 18 portions of Herb Gynostemmae Pentaphylli 4 ~ 15 parts of Cornu Saigae Tataricae 2 ~ 12 parts.
2. the instant particles as Chinese medicine for the treatment of for ICU myasthenia gravis and nursing according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
Radix Fici beecheyanae 69 ~ 82 portions of Fructus Jujubaes 66 ~ 80 parts of Radix Uncariae rhynchophyllaes 63 ~ 77 parts of Radix Seu Caulis Mucunae Sempervirentis 60 ~ 74 parts
Radix Pedicularis Henryi 57 ~ 70 parts of Radixs Astragali 54 ~ 66 parts of Radix seu Caulis Verntilaginis Leiocarpae 50 ~ 63 parts of Radix potentillae anserinae 48 ~ 60 parts
36 ~ 50 parts, Semen glycines sojae 45 ~ 58 parts of Folium Nelumbinis 42 ~ 55 parts of Caulis Polygoni Multiflori 39 ~ 52 portions of Radix Glycyrrhizaes
Radix Akebiae 33 ~ 45 portions of Fructus Chaenomeliss 30 ~ 42 parts of Radix cynanchi wilfordii 27 ~ 38 portions of Radix Paeoniae Albas 24 ~ 35 parts
13 ~ 22 parts, Fructus Ligustri Lucidi 21 ~ 32 parts of Radix Angelicae Pubescentiss 18 ~ 28 parts of Herba goodyearae repentis 15 ~ 25 parts of river Cortex cinnamomi japonici (Ramulus Cinnamomi)s
Cortex Acanthopancis 10 ~ 20 parts of Fructus Amomis 8 ~ 15 portions of Herb Gynostemmae Pentaphylli 6 ~ 12 parts of Cornu Saigae Tataricae 4 ~ 8 parts.
3. the instant particles as Chinese medicine for the treatment of for ICU myasthenia gravis and nursing according to claim 1, is characterized in that, raw material composition and the parts by weight of making described effective ingredient are:
Radix Fici beecheyanae 76 portions of Fructus Jujubaes 73 parts of Radix Uncariae rhynchophyllaes 69 parts of Radix Seu Caulis Mucunae Sempervirentis 66 parts
Radix Pedicularis Henryi 63 parts of Radixs Astragali 60 parts of Radix seu Caulis Verntilaginis Leiocarpae 57 parts of Radix potentillae anserinae 54 parts
42 parts, Semen glycines sojae 51 parts of Folium Nelumbinis 48 parts of Caulis Polygoni Multiflori 45 portions of Radix Glycyrrhizaes
Radix Akebiae 39 portions of Fructus Chaenomeliss 36 parts of Radix cynanchi wilfordii 33 portions of Radix Paeoniae Albas 30 parts
17 parts, Fructus Ligustri Lucidi 27 parts of Radix Angelicae Pubescentiss 23 parts of Herba goodyearae repentis 20 parts of river Cortex cinnamomi japonici (Ramulus Cinnamomi)s
Cortex Acanthopancis 14 parts of Fructus Amomis 11 portions of Herb Gynostemmae Pentaphylli 8 parts of Cornu Saigae Tataricae 6 parts.
4., for the treatment of ICU myasthenia gravis and the preparation method of the instant particles as Chinese medicine of nursing, it is characterized in that, comprise following processing step:
(1) Radix Fici beecheyanae, Fructus Jujubae, Radix Uncariae rhynchophyllae, Radix Pedicularis Henryi, Radix potentillae anserinae, Semen glycines sojae, Folium Nelumbinis, Caulis Polygoni Multiflori, Radix Glycyrrhizae, Radix cynanchi wilfordii, river Cortex cinnamomi japonici (Ramulus Cinnamomi), Cortex Acanthopancis, Fructus Amomi, Herb Gynostemmae Pentaphylli are cleaned, dry rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; In remaining medicinal residues, add the water of 4 ~ 6 times amount again, heated and boiled 1 ~ 2 hour, gets immersion after cooling; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Radix Seu Caulis Mucunae Sempervirentis, Radix seu Caulis Verntilaginis Leiocarpae, Radix Akebiae, Radix Angelicae Pubescentis, Herba goodyearae repentis are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) astragalus mongholicus tablet is added cooked Mel and a little boiled water, mixes thoroughly slightly vexed, put in pot fry to yellow and tack-free time, take out and dry in the air cool, pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(4) put in pot by papaya tablet, fry to micro-Jiao's degree of being with slow fire, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(5) get Radix Paeoniae Alba sheet, spray yellow wine is mixed thoroughly, and after slightly vexed, put with slow fire heating in pot, fried dry, taking-up cools, and pulverizing is ground into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(6) get clean Fructus Ligustri Lucidi to add yellow wine and mix thoroughly, put in appropriate vessel, airtight, sit in kettle, stewing out of water exhausts to wine, takes out, dry, pulverize and grind into powder, crosses 100 order dusting covers, obtains fine powder, for subsequent use;
(7) grind into powder after Cornu Saigae Tataricae being pulverized, cross 100 order dusting covers, obtain fine powder, for subsequent use;
(8) by the thick paste of step (1), step (2) gained, after in step (3), step (4), step (5), step (6), step (7), the fine powder of gained mixes, add adjuvant sucrose and dextrin mix homogeneously makes granule, after drying, granulate, be packaged into the instant particles as Chinese medicine often wrapping 10g.
CN201510852960.5A 2015-11-27 2015-11-27 Traditional Chinese medicine electuary for treatment and nursing of ICU myasthenia gravis and preparation method Pending CN105250887A (en)

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CN105596697A (en) * 2016-02-15 2016-05-25 赵玉洁 Traditional Chinese medicine electuary for treating tourette syndrome of children and preparation method
CN105687738A (en) * 2016-03-09 2016-06-22 陈征远 Traditional Chinese medicine granules for treating intractable coughs and preparation method
CN105688002A (en) * 2016-03-10 2016-06-22 窦彩艳 Traditional Chinese medicine granules for treating senile functional constipation and preparation method
CN105816672A (en) * 2016-03-30 2016-08-03 魏瑞雪 Traditional Chinese medicine dissolved medicine for auxiliary discharge after urinary system ultrasonic lithotripsy and preparation method
CN106038995A (en) * 2016-07-15 2016-10-26 夏雪飞 Traditional Chinese medicine granules for treating perioral dermatitis and preparation method

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596697A (en) * 2016-02-15 2016-05-25 赵玉洁 Traditional Chinese medicine electuary for treating tourette syndrome of children and preparation method
CN105687738A (en) * 2016-03-09 2016-06-22 陈征远 Traditional Chinese medicine granules for treating intractable coughs and preparation method
CN105688002A (en) * 2016-03-10 2016-06-22 窦彩艳 Traditional Chinese medicine granules for treating senile functional constipation and preparation method
CN105816672A (en) * 2016-03-30 2016-08-03 魏瑞雪 Traditional Chinese medicine dissolved medicine for auxiliary discharge after urinary system ultrasonic lithotripsy and preparation method
CN106038995A (en) * 2016-07-15 2016-10-26 夏雪飞 Traditional Chinese medicine granules for treating perioral dermatitis and preparation method

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