CN105816672A

CN105816672A - Traditional Chinese medicine dissolved medicine for auxiliary discharge after urinary system ultrasonic lithotripsy and preparation method

Info

Publication number: CN105816672A
Application number: CN201610191905.0A
Authority: CN
Inventors: 魏瑞雪; 崔岩; 王凌燕; 任玮; 魏静
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-03-30
Filing date: 2016-03-30
Publication date: 2016-08-03

Abstract

The invention discloses a traditional Chinese medicine dissolved medicine for auxiliary discharge after urinary system ultrasonic lithotripsy and a preparation method, and belongs to the field of traditional Chinese medicine. The effective ingredients of the medicine comprise herba lysimachiae, obcordate aspidopterys stems, milkvetch roots, herba euonymi, rust-coloured crotalaria herb with roots, radix cycleae hypoglaucae, semen cuscutae, licorice roots, herba ecliptae, Japanese berry-bearing campion herb, radix angelica sinensis, big rattlesnake plantain herb, herba achyranthis asperae, asiatic alectoria filaments, radix paeoniae alba, barbary wolfberry fruit, chingma abutilon seeds, rhizoma chuanxiong, hairyleaf litse fruit, plane-stem spleenwort, loofah sponges, goose gizzard-membranes and yellow croaker ear-stones. According to the traditional Chinese medicine dissolved medicine, the selected medicinal materials accord with the monarch, minister, adjuvant and messenger principle; the dissolved medicine is applied according to indications for the pathogenesis, has the effects of nourishing the kidney and the liver, benefiting qi and nourishing the blood, clearing away heat and toxic materials, dissolving and discharging calculi, inducing diuresis for treating stranguria, promoting qi to activate the blood, stopping bleeding and dispersing blood stasis, relaxing the muscles and the tendons and removing obstruction from meridians and relieving swelling and pain and is good in adsorption effect, significant in treatment effect and free of toxic and side effects and clinical adverse effects; the cure rate on the urinary calculi is high through clinical verification.

Description

Instant particles as Chinese medicine and the preparation method of discharge is assisted after the ultrasonic rubble of urinary system

Art

The present invention relates to the field of Chinese medicines, particularly for the instant particles as Chinese medicine and the preparation method that assist discharge after the ultrasonic rubble of urinary system.

Background technology

Urinary calculi is called for short urinary calculi, refers to form granule or in bulk sample aggregation at urinary system endogenous cause of ill urine concentrating and precipitating, including renal calculus, ureteral calculus, vesical calculus and lithangiuria, commonly encountered diseases, is apt to occur in person between twenty and fifty, and sickness rate is on the rise in recent years.It it is one of modal urological diseases.Male is more than women, about 4～5: 1.Its origin cause of formation illustrates the most completely, can induce because of factors such as urinary tract infection, urinary tract obstruction, foreign body, metabolism disorders.Having multiple theory, relapse rate is high, and most calculus be there is no very good prevention method.Urinary calculus morbidity has provincialism, is more common on the south the Changjiang river in China, and the north is the most rare.

Urinary calculi clinical manifestation differs greatly, and the lighter is asymptomatic, and typical case person shows as lumbago and hematuria, and part may occur in which the symptom of the urinary tract infection such as frequent micturition, urgent micturition, dysurea, and severe patient may result in urinary tract obstruction and renal dysfunction.The clinical Therapeutic Method to urinary system calculus of doctor trained in Western medicine mainly includes that medicine calculus, ultrasound wave rubble, open surgery take stone etc. at present.Western medicine drug calculus, only urate and cystine stone are the most effective, if using a period of time not have positive effect, are further continued for employing the most nonsensical.And open surgery takes stone to patient body injury relatively greatly, the hospital stays is long, and rehabilitation is slow, the patient being relatively large in diameter except some calculus, general it is not recommended that use.Needing after ultrasound wave rubble to discharge rubble by urethra, it is only necessary to drink water after rubble, moderate exercise helps to get rid of rubble more, to human body almost without Accessory injury, painful little during calculus, is typically not required in hospital, and it is low to control furuncle expense, and patient is acceptant.But ultrasound wave is while smashing calculus, unavoidably tissue is produced corresponding destruction, mucosa may be affected and cause local hemorrhage, and cause adjacent tissue swelling, hemorrhage and hematoma, after causing the ultrasonic rubble of patient, the symptom such as lumbago, hematuria occur.Need to carry out the symptomatic treatments such as some spasmolytic, pain relieving, fluid infusion, antiinflammatory after the most general ultrasonic rubble.

Urinary calculi belongs to Chinese medicine " stranguria caused by urinary stone ", " sand Stranguria ", " stranguria with blood " category.Its Etiological deficiency of kidney-QI is taken advantage of by heat, and functioning of bladder is not normal, stagnation of QI-blood, the damp-heat accumulation part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, and in urine, impurity gathers for sandstone, urethral obstruction, mechanism of qi stagnation of QI and blood may bring about pain.The present invention is through long-term clinical practice, suit the remedy to the case according to the cause of disease, there is nourishing the kidney and liver, vigorate qi and replenish the blood, heat-clearing and toxic substances removing, calculus dissolving and excreting, inducing diuresis for treating stranguria syndrome, promoting flow of QI and blood, hemostasis repercussive, channels sootheing and network vessel quickening, effect of reducing swelling and alleviating pain, damage to renal tissue when can quickly repair ultrasonic rubble, hemostasia and detumescence, reduce inflammation, waist pain-relieving, increases urine volume, lax tube chamber, tonneau water channel, thus discharge for rubble and create favorable conditions, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to urinary calculi cure rate according to clinical verification.

Summary of the invention

Instant particles as Chinese medicine and the preparation method of discharge is assisted after present invention provide for the ultrasonic rubble of urinary system, there is nourishing the kidney and liver, vigorate qi and replenish the blood, heat-clearing and toxic substances removing, calculus dissolving and excreting, inducing diuresis for treating stranguria syndrome, promoting flow of QI and blood, hemostasis repercussive, channels sootheing and network vessel quickening, effect of reducing swelling and alleviating pain, curing the disease and seek source treating both the principal and secondary aspects of a disease, the multiple urinary calculi causing a variety of causes is respectively provided with good curative effect.

For achieving the above object, technical scheme is implemented as follows:

After the ultrasonic rubble of urinary system, assist the instant particles as Chinese medicine of discharge, make described effective ingredient raw material composition and parts by weight be:

Herba Lysimachiae 70～85 parts, Caulis Aspidopterydis obcordatae 68～82 parts, the Radix Astragali 65～78 parts, Caulis Seu Folium Euonymi Fortunei 62～75 parts,

Herba Crotalariae Ferrugineae 59～72 parts, Radix Ilicis Asprellae rattan 56～69 parts, Semen Cuscutae 53～66 parts, Radix Glycyrrhizae 50～63 parts,

Herba Ecliptae 47～60 parts, Herba Cucubali japonici 44～56 parts, Radix Angelicae Sinensis 40～53 parts, Herba goodyearae repentis 36～50 parts,

Radix achyranthis asperae (Herba Achyranthis Asperae) 33～47 parts, Alectoria asiatica Du Rietz 30～44 parts, the Radix Paeoniae Alba 27～40 parts, Fructus Lycii 24～37 parts,

Semen Abutili 21～33 parts, Herba Aristolochiae 18～30 parts, Rhizoma Chuanxiong 15～26 parts, clear Fructus Solani melongenae 12～23 parts,

Asplenium planicaule wall 9～20 parts, Retinervus Luffae Fructus 6～16 parts, Endothelium corneum Anseris domestica 3～12 parts, Asteriscus Pseudosciaenae 1～9 parts.

Make described effective ingredient raw material composition and parts by weight be:

Herba Lysimachiae 73～82 parts, Caulis Aspidopterydis obcordatae 70～80 parts, the Radix Astragali 68～75 parts, Caulis Seu Folium Euonymi Fortunei 65～72 parts,

Herba Crotalariae Ferrugineae 62～69 parts, Radix Ilicis Asprellae rattan 60～66 parts, Semen Cuscutae 57～63 parts, Radix Glycyrrhizae 53～60 parts,

Herba Ecliptae 50～57 parts, Herba Cucubali japonici 47～53 parts, Radix Angelicae Sinensis 43～50 parts, Herba goodyearae repentis 40～47 parts,

Radix achyranthis asperae (Herba Achyranthis Asperae) 36～44 parts, Alectoria asiatica Du Rietz 33～40 parts, the Radix Paeoniae Alba 30～37 parts, Fructus Lycii 27～34 parts,

Semen Abutili 24～30 parts, Herba Aristolochiae 21～27 parts, Rhizoma Chuanxiong 18～23 parts, clear Fructus Solani melongenae 15～20 parts,

Asplenium planicaule wall 12～18 parts, Retinervus Luffae Fructus 8～14 parts, Endothelium corneum Anseris domestica 5～10 parts, Asteriscus Pseudosciaenae 3～6 parts.

Herba Lysimachiae 78 parts, Caulis Aspidopterydis obcordatae 75 parts, the Radix Astragali 72 parts, Caulis Seu Folium Euonymi Fortunei 69 parts, Herba Crotalariae Ferrugineae 66 parts,

63 parts of Radix Ilicis Asprellae rattan, Semen Cuscutae 60 parts, 57 parts of Radix Glycyrrhizae, Herba Ecliptae 54 parts, Herba Cucubali japonici 50 parts,

Radix Angelicae Sinensis 47 parts, Herba goodyearae repentis 44 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 40 parts, Alectoria asiatica Du Rietz 36 parts, the Radix Paeoniae Alba 33 parts,

Fructus Lycii 30 parts, Semen Abutili 27 parts, Herba Aristolochiae 24 parts, Rhizoma Chuanxiong 21 parts, clear Fructus Solani melongenae 18 parts,

Asplenium planicaule wall 15 parts, Retinervus Luffae Fructus 12 parts, Endothelium corneum Anseris domestica 8 parts, Asteriscus Pseudosciaenae 4 parts.

After the ultrasonic rubble of urinary system, assist the preparation method of the instant particles as Chinese medicine of discharge, comprise the following steps that:

(1) Caulis Aspidopterydis obcordatae, Herba Crotalariae Ferrugineae, Radix Ilicis Asprellae rattan, Semen Cuscutae, Herba Ecliptae, Herba Cucubali japonici, Radix Angelicae Sinensis, Radix achyranthis asperae (Herba Achyranthis Asperae), Alectoria asiatica Du Rietz, Fructus Lycii, Semen Abutili, Herba Aristolochiae, clear Fructus Solani melongenae are cleaned and dried rear mix homogeneously, put in container, add the water of 6～8 times amount in a reservoir, heated and boiled 2～3 hours, take immersion after cooling；In remaining medicinal residues, add the water of 4～6 times amount, heated and boiled 1～2 hours, after cooling, take immersion；Merging twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15～1.25, standby；

(2) Herba Lysimachiae, Caulis Seu Folium Euonymi Fortunei, Herba goodyearae repentis, Asplenium planicaule wall are put in container, add the shao-hsing rice wine of 3～5 times amount, cool after boiling, continue to soak 3～5 hours, take immersion；In remaining medicinal residues, add the shao-hsing rice wine of 2～4 times amount, put after boiling and dry in the air, continue to soak 2～4 hours, take immersion；Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10～1.20, standby；

(3) astragalus mongholicus tablet is added cooked Mel and a little boiled water, mixes thoroughly the most vexed, fry in putting pot to yellow and tack-free time, take out and dry in the air cool, pulverizing is ground into powder, crosses 100 mesh dusting covers, obtains fine powder, standby；

(4) take clean Radix Glycyrrhizae tabellae, add cooked Mel and a little boiled water, the most vexed after mixing thoroughly, to put in parch container, slow fire is fried to yellow to buff, takes out, cool time tack-free, and pulverizing is ground into powder, crosses 100 mesh dusting covers, obtains fine powder, standby；

(5) taking Radix Paeoniae Alba sheet, spray yellow wine is mixed thoroughly, the most vexed after, heat with slow fire in putting pot, fried dry, taking-up cools, and pulverizing is ground into powder, crosses 100 mesh dusting covers, obtains fine powder, standby；

(6) taking Rhizoma Chuanxiong sheet yellow wine and spray uniformly, the most vexed, frying in putting pot to micro-Jiao is degree, and taking-up cools, and pulverizing is ground into powder, crosses 100 mesh dusting covers, obtains fine powder, standby；

(7) taking and be cut into the Retinervus Luffae Fructus of segment, stir to yellow degree of being with wheat bran, take out, sieve removes wheat bran, cools, and pulverizing is ground into powder, crosses 100 mesh dusting covers, obtains fine powder, standby；

(8) first sand being put into pot to make popular, then the Endothelium corneum Anseris domestica cleaned is put in pot, stir with slow fire and heave to brown color or coke yellow, take out, sieve removes sand, cools, and pulverizing is ground into powder, crosses 100 mesh dusting covers, obtains fine powder, standby；

(9) drying clean for Asteriscus Pseudosciaenae, put in ferrum spoon, overlying one bowl, after being calcined to cracker on raging fire, taking-up cools, and pulverizing is ground into powder, crosses 100 mesh dusting covers, obtains fine powder, standby；

(10) by step (1), the thick paste of step (2) gained, with the fine powder of gained in step (3), step (4), step (5), step (6), step (7), step (8), step (9), granule is made after adding adjuvant sucrose and dextrin mix homogeneously, it is dried, after granulate, is packaged into the instant particles as Chinese medicine of every bag of 10g.

The property of medicine of Chinese medicine used by the present invention is as follows:

Herba Lysimachiae: sweet in the mouth；Micro-hardship；Cool in nature.Enter liver；Gallbladder；Kidney；Bladder warp.Relieving stranguria by diuresis；Heat-clearing and toxic substances removing；Dissipating blood stasis for subsidence of swelling.Cure mainly liver and gall and urinary system calculus；Pyretic stranguria；Oedema due to nephritis；Jaundice due to damp-heat；Sore carbuncle；Venom；Traumatic injury.Modern medicine study confirms, Herba Lysimachiae mainly containing phenolic constituent and sterol, flavonoid, tannin, volatile oil, choline, potassium salt etc., has calculus, antibacterial, treating stranguria, antiinflammatory action, humoral immunization, cellular immunization are all had obvious inhibitory action.

Caulis Aspidopterydis obcordatae: lightly seasoned；Puckery；Cold nature.Return bladder warp.Antiinflammatory diuresis, heat clearing away calculus.Control urinary tract infection, cystitis, lithangiuria, rheumatic ostalgia, puerperal asthenia, inappetence.

The Radix Astragali: sweet in the mouth；Warm in nature.Enter the heart；Lung；Spleen；Kidney channel.Invigorating QI to consolidate the body surface resistance；Diuresis；Expelling pus and toxin by strengthening QI；Promoting tissue regeneration and ulcer healing.Cure mainly cardiopalmus of breathing hard；Asthenia；Weak；Spontaneous perspiration；Night sweat；Chronic diarrhea；Proctoptosis；Body is impractical swollen；Uterine prolapse；Chronic nephritis；Carbuncle difficulty is burst；Or burst do not hold back for a long time." Xinhua's book on Chinese herbal medicine outline " carries: " have the function of invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting." modern medicine study confirms; the Radix Astragali is mainly composed of Radix Astragali total flavones, Radix Astragali Mongolici total polysaccharide, Radix Astragali total saponins and aminoacid etc.; have diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxidant radical generate and improve the multiple pharmacological effect such as body's immunity; can act on body from many aspects, improves the relevant blood vessel sexually transmitted disease (STD)s such as cardiovascular, cerebrovascular, diabetes, nephropathy and becomes the function such as hemodynamics and vascular endothelial cell of patient.

Caulis Seu Folium Euonymi Fortunei: bitter in the mouth；Sweet；Micro-pungent；Slightly warm in nature.Return liver；Spleen；Kidney channel.Relaxing muscles and tendons and activating QI and blood in the collateral；Kidney tonifying strengthens waist；Hemostasis repercussive.Cure mainly soreness of waist and knee joint of suffering from a deficiency of the kidney；Hemiplegia；Rheumatic arthralgia；Infantile convulsion；Spitting of blood；Spit blood；Metrorrhagia；Have through uncomfortable；Uterine prolapse；Injury and bone fracture；Wound hemorrhage." will planted by Tianmu Mountains of Zhejiang Province medicine ": promoting flow of QI and blood.Control lumbocrural pain, joint aches.

Herba Crotalariae Ferrugineae: the micro-acid of bitter in the mouth；Property flat cold.Return lung meridian.Nourishing the kidney and liver, relieving cough and asthma, eliminating damp, detoxifying.Cure mainly tinnitus, deaf, the vertigo, seminal emission, menorrhagia, leucorrhea, chronic cough expectorant blood, asthma, nephritis, dysuria, tonsillitis, parotitis, furuncle swelling toxin." vegetation just side ": invigorating the spleen and replenishing QI, treats tinnitus, and the head is giddy, collapses pouring.Pathogenic fire purging heat clearing away again, suppressing liver-wind, detumescence pain.

Radix Ilicis Asprellae rattan: bitter in the mouth；Cold in nature.Return lung；Large intestine；Liver Channel.Heat-clearing and toxic substances removing；Wind-expelling pain-stopping；Relieving stranguria by diuresis.Cure mainly: anemopyretic cold；Cough；Laryngopharynx swelling and pain；Diphtheria；Acute toothache；Enteritis；Dysentery；Urinary tract infection and lithangiuria；Rheumatalgia；Sore swollen toxin；Venom.

Semen Cuscutae: acrid in the mouth；Sweet；Property flat.Enter liver；Kidney；Spleen channel.The kidney invigorating and essence nourishing；Nourishing the liver to improve visual acuity；Gu tire stopping leak.Cure mainly soreness of waist and knee joint；Seminal emission；Sexual impotence；Premature ejaculation；Sterile；Quench one's thirst；Stranguria with turbid discharge；The enuresis；Blurred vision tinnitus；Frequent fetal movement；Miscarriage；Have loose bowels." book on Chinese herbal medicine converge with speech " carries: " tonifying kidney and nourishing liver, warming the spleen helps the medicine of stomach also, but mends and the highest, temperature and the driest, void can be mended, in fact can be in order to, cold can temperature, heat can be cool, and temperature can be dry, dry can moisten." modern medicine study confirm, Semen Cuscutae can significantly protect hepatic injury activity, increase nonspecific resistance, enhancement vigor, in addition with antitumor, antiinflammatory, antisterility, diarrhea inducing and suppression central nervous system effect.

Radix Glycyrrhizae: sweet in the mouth；Property flat.GUIXIN；Lung；Spleen；Stomach warp.Invigorating the spleen and replenishing QI；Heat-clearing and toxic substances removing；Expelling phlegm for arresting cough；Relieving spasm to stop pain；Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach；Fatigue and weakness；Shortness of breath and palpitation；Cough with copious phlegm；Gastral cavity abdomen four muscle spasm of the leg and foot pain；Carbuncle sore tumefacting virus；Cushion toxicity.Compendium of Material Medica carries: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, solution 1,002 poison of draft by every means, be in harmonious proportion and gain merit from medicine." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, lowering blood pressure and blood fat, antitumaous effect; is widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, additionally has anti-gastric-ulcer, gastritis effect.

Herba Ecliptae: sweet in the mouth；Acid；Cool in nature.Return liver；Kidney channel.Liver and kidney tonifying；Cooling blood for hemostasis.Cure mainly: deficiency of the liver and kindey；Have a dizzy spell；Early whitening of beard and hair；Spit blood；Spitting of blood；Epistaxis；Have blood in stool；Dysentery；Collapse；Leakage；Traumatic hemorrhage." classifying herbal ": hemostasis, the kidney invigorating, annealing, detumescence.Control pouring, collapse.

Herba Cucubali japonici: lightly seasoned；Property flat.Inducing diuresis for treating stranguria syndrome；Promoting the circulation of QI to relieve pain；The continuous wound of synthetism.Cure mainly pyretic stranguria；Stranguria caused by urinary stone；Stranguria with blood；Wet cloudy stagnation of QI abdominal distention；Traumatic pain.

Radix Angelicae Sinensis: sweet in the mouth；Pungent；Warm in nature.Return liver, the heart, spleen channel.Replenishing and activating blood；Menstruction regulating and pain relieving；Loosening bowel to relieve constipation.Cure mainly blood deficiency and yellow complexion；Dizziness cardiopalmus；Asthenia cold abdominalgia；Rheumatic arthralgia；Injury from falling down；Ulcer sores." book on Chinese herbal medicine is just " carries: " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable." modern medicine study confirmation, Radix Angelicae Sinensis has antibacterial, antiinflammation, and chronic articular rheumatism acute attack is had obvious inhibitory action.

Herba goodyearae repentis: sweet in the mouth；Pungent；Property flat.Nourishing the lung to arrest cough；Tonify Qi of the kidney；Promoting flow of QI and blood；Subduing swelling and detoxicating.Cure mainly pulmonary tuberculosis cough；Tracheitis；Dizzy weak；Neurasthenia；Sexual impotence；Traumatic injury；Arthralgia；Laryngopharynx swelling and pain；Acute mastitis；Furuncle；Scrofula." Chinese herbal medicine is commonly used in Tibet ": " hard masses softening and resolving.Control scrofula."

Radix achyranthis asperae (Herba Achyranthis Asperae): bitter in the mouth；Acid；Cold nature.Return liver；Lung；Bladder warp.Blood circulation promoting and blood stasis dispelling；Inducing diuresis for treating stranguria syndrome；Clearing away heat and expelling pathogen in the exterior.Cure mainly amenorrhea；Dysmenorrhea；Menoxenia；Traumatic injury；Rheumatic arthritis；Gonorrhea；Edema；Damp-heat vaginal discharge, fever caused by exogenous pathogens；Malaria；Pharyngalgia；Furuncle carbuncle." conventional Chinese herbal medicine handbook ": heat clearing away, diuretic, strong muscle, dissipates blood.Cure cold heating, and long heat is not moved back, rheumatic arthritis, lumbago and skelalgia, laryngalgia, hypertension, oedema due to nephritis.

Alectoria asiatica Du Rietz: lightly seasoned；Property flat.Return liver；Kidney；Bladder warp.Nourishing the kidney and liver；Arresting seminal emission hidroschesis；Inducing diuresis to remove edema；Removing dampness sore.Cure mainly kidney deficiency and bodily weakness；The vertigo；Cardiopalmus；Seminal emission；Night sweat；Stranguria；Edema；Impetigo.

The Radix Paeoniae Alba: bitter in the mouth；Property flat.Enter liver；Spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving；Yin fluid astringing receives antiperspirant.Curing mainly the chest and abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency." not Lu " carries: " clear and coherent blood vessels, slow in, dispelling malignant blood, expelling extravasated blood, go aqueous vapor, profit bladder, intestine and small intestine, subduing inflammation, row cold and heat when controlling, attacked by pestiferous factors suffers from abdominal pain, lumbago." modern medicine study confirms; the Radix Paeoniae Alba can regulate immunity; strengthen macrophage and the phagocytic function of leukocyte; regulate T lymphocyte and the immunologic function of body fluid; protects the liver, spasmolytic, analgesia, calmness, resist cool, cooling effect; additionally has inhibitory action, enhancing anoxia enduring, antioxidation and the effect of resisting fatigue to smooth muscle.

Fructus Lycii: sweet in the mouth；Property flat.Return liver；Kidney；Lung meridian.Nourishing the liver；Nourishing kidney；Lung moistening.Cure mainly caused by liver and kidney deficiency；Have a dizzy spell；Visual one clear；Soreness of the waist and knees；The expensive essence of sexual impotence；Cough due to consumptive disease；Quench one's thirst taking fluids profusely." book on Chinese herbal medicine is just " carries: " bright knowledge, adds the solid marrow of essence, strengthen the muscle and bone, and kind benefit impairment caused by overstrain is the most only quenched one's thirst." modern medicine study confirms, Fructus Lycii scalable body's immunity, can effectively suppress tumor growth and cell mutation, have slow down aging, anti-fatty liver, regulation blood fat and the effect of the aspect such as blood glucose, promotion hemopoietic function.

Semen Abutili: sweet in the mouth；Cold in nature.Return large intestine；Small intestinal；Liver；Lung；Stomach；Bladder warp.Relieving stranguria by diuresis；Laxation relieving constipation；Stimulating milk secretion.Cure mainly urinary obstruction, urinary tract infection, urinary system calculus, lack of lactation after delivery etc.." herbal classic ": main the five internal organs six mansion cold and heat weakness and emaciation, five is infirmity, diuresis.

Herba Aristolochiae: bitter in the mouth；Warm in nature.Return liver；Spleen；Kidney channel.Promoting flow of QI and blood；Inducing diuresis to remove edema；Removing toxic substances.Cure mainly stomachache；Colicky；Edema during pregnancy；Puerperal, vim and vigour were suffered from abdominal pain；Snake bite and insect sting." book on Chinese herbal medicine converges and says ": Herba Aristolochiae, gas is invigorated blood circulation, and controls the medicine of all pains also.The gas of the person, suitable then peaceful, the inverse then vexed work of pain.As Young " side of directing at " Herba Aristolochiae controls expectorant note brachialgia, gas stays colic, and abdominal mass is gathered, and renal mass is suffered from abdominal pain, puerperal vim and vigour stomachache, he is such as edema during pregnancy, edema over the face tachypnea, man's wind labor, and chronic cough is not healed, and knows and controls it with this medicine, peace of invariably getting into bed.Gai Weiqi be good at popular vim and vigour thus also.

Rhizoma Chuanxiong: acrid in the mouth；Warm in nature.Return liver；Gallbladder；Pericardium channel.Blood circulation promoting and blood stasis dispelling；Activating QI to alleviate the depression；Wind-expelling pain-stopping.Cure mainly abdominal mass lump；Pain in chest and hypochondrium；Headache dizziness；Anemofrigid-damp arthralgia；Traumatic injury；Ulcer sores." book on Chinese herbal medicine is just " carries: " dispersing wind and cold, controls pain, and removing blood stasis with potent drugs stores, promoting blood circulation, solves stagnation of QI, and by pain, evacuation of pus is subsided a swelling, stimulated the menstrual flow by blood." modern medical science research discovery; Rhizoma Chuanxiong extracting solution has certain effect to suppression leukaemia; preparation has certain antibacterial action; especially Bacillus typhi, Salmonella paratyphi, vibrio cholera, bacillus pyocyaneus and pathogenic dermatophytes etc. are all had inhibitory action; the ligustrazine contained by Rhizoma Chuanxiong, ferulic acid are received has blood circulation invigorating efficacies; expansible coronary artery, promote coronary flow, allevating angina pectoris, and there is anti-thrombosis function, contained cnidium lactone has smooth muscle spasmolysis and the suppression effect such as myenteron, uterine contraction.

Clear Fructus Solani melongenae: acrid in the mouth；Micro-hardship；Warm in nature.Return spleen；Stomach；Kidney channel.Warming middle-JIAO to relieve pain；Promoting flow of QI and blood；Relieving asthma；Diuresis.Cure mainly coldness and pain in the epigastrium；Food stagnation flatulence；Regurgitation is vomitted；Heatstroke is vomited and diarrhoea；Dysentery；Colic of cold type is suffered from abdominal pain；Asthma；Cold-damp dropsy；Dysuria；Turbid urine；Sore swollen toxin；Toothache；Arthralgia due to cold-dampnes；Traumatic injury.Modern medicine study proves: clear Fructus Solani melongenae has antiplatelet aggregative activity, resist myocardial ischemia and myocardial infarction effect, relieving asthma and anti-allergic effects, antibacterial action and litholytic effect.

Asplenium planicaule wall: lightly seasoned；Micro-puckery；Cool in nature.Return liver；Kidney channel.Channels sootheing and network vessel quickening；Promoting blood circulation and stopping pain.Cure mainly lumbago." Xinhua's book on Chinese herbal medicine outline ": herb: lightly seasoned, micro-puckery, cool in nature.There is the function of relaxing muscles and tendons to promote blood circulation.For lumbago.

Retinervus Luffae Fructus: bitter in the mouth；Cool in nature.Return lung；Liver；Stomach warp.Dredge the meridian passage, heat-clearing and toxic substances removing, inducing diuresis to remove edema, hemostasis.Cure mainly distending pain in the chest and hypochondrium, rheumatic arthralgia, muscle arteries and veins contracture, woman's amenorrhea, galactostasis, phlegm-heat cough, pyretic toxicity carbuncle, anal fistula, edema, dysuria, have blood in stool, metrorrhagia." book on Chinese herbal medicine is just read ": Retinervus Luffae Fructus, enters meridians, solves pathogenic heat.Evanescence of heat then wind goes, and in network, body fluid will not be tied combined into expectorant, becomes all diseases of toxic swelling, the ear therefore cloud detoxifies.Modern medicine study proves: Retinervus Luffae Fructus has therapeutical effect to hepar damnification, and has heart tonifying diuresis and antineoplastic effect.

Endothelium corneum Anseris domestica: sweet in the mouth；Puckery；Property flat；Return spleen channel.Strengthening the spleen to promote digestion；Arresting seminal emission；Digestion stone.Cure mainly dyspepsia；Dysentery；Infantile malnutrition；The seminal emission enuresis；Urinary system calculus；Cholelithiasis；Abdominal mass amenorrhea.

Asteriscus Pseudosciaenae: sweet in the mouth；Salty；Cold in nature.Return bladder warp.Inducing diuresis for treating stranguria syndrome；Heat-clearing and toxic substances removing.Cure mainly: stranguria caused by urinary stone；Dribbling urination is the most smooth；Rhinitis；Suppurative otitis media." Japan hanako materia medica ": take pillow in brain and burn for last, under drink, control stranguria caused by urinary stone.

The present invention compared with prior art, has the advantages that

The present invention selects medical material monarch, minister, left, make all reasons the most standby, the property of medicine is suitable mutually auxiliary mutually, suit the remedy to the case for causing the cause of disease, there is nourishing the kidney and liver, vigorate qi and replenish the blood, heat-clearing and toxic substances removing, calculus dissolving and excreting, inducing diuresis for treating stranguria syndrome, promoting flow of QI and blood, hemostasis repercussive, channels sootheing and network vessel quickening, effect of reducing swelling and alleviating pain, damage to renal tissue when can effectively repair rubble, hemostasia and detumescence, reduce inflammation, waist pain-relieving, increase urine volume, lax tube chamber, tonneau water channel, thus discharge for rubble and create favorable conditions, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to urinary calculi cure rate according to clinical verification.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

The raw material of effective ingredient of the present invention forms and weight is:

Herba Lysimachiae 70～85g, Caulis Aspidopterydis obcordatae 68～82g, the Radix Astragali 65～78g, Caulis Seu Folium Euonymi Fortunei 62～75g,

Herba Crotalariae Ferrugineae 59～72g, Radix Ilicis Asprellae rattan 56～69g, Semen Cuscutae 53～66g, Radix Glycyrrhizae 50～63g,

Herba Ecliptae 47～60g, Herba Cucubali japonici 44～56g, Radix Angelicae Sinensis 40～53g, Herba goodyearae repentis 36～50g,

Radix achyranthis asperae (Herba Achyranthis Asperae) 33～47g, Alectoria asiatica Du Rietz 30～44g, the Radix Paeoniae Alba 27～40g, Fructus Lycii 24～37g,

Semen Abutili 21～33g, Herba Aristolochiae 18～30g, Rhizoma Chuanxiong 15～26g, clear Fructus Solani melongenae 12～23g,

Asplenium planicaule wall 9～20g, Retinervus Luffae Fructus 6～16g, Endothelium corneum Anseris domestica 3～12g, Asteriscus Pseudosciaenae 1～9g.

The processing step of process for preparing medicine of the present invention is:

Usage and dosage: half an hour ante cibum takes after mixing it with water with boiled water, each 1 bag, three times a day, 7 days be 1 course for the treatment of.Embodiment 2

Herba Lysimachiae 73～82g, Caulis Aspidopterydis obcordatae 70～80g, the Radix Astragali 68～75g, Caulis Seu Folium Euonymi Fortunei 65～72g,

Herba Crotalariae Ferrugineae 62～69g, Radix Ilicis Asprellae rattan 60～66g, Semen Cuscutae 57～63g, Radix Glycyrrhizae 53～60g,

Herba Ecliptae 50～57g, Herba Cucubali japonici 47～53g, Radix Angelicae Sinensis 43～50g, Herba goodyearae repentis 40～47g,

Radix achyranthis asperae (Herba Achyranthis Asperae) 36～44g, Alectoria asiatica Du Rietz 33～40g, the Radix Paeoniae Alba 30～37g, Fructus Lycii 27～34g,

Semen Abutili 24～30g, Herba Aristolochiae 21～27g, Rhizoma Chuanxiong 18～23g, clear Fructus Solani melongenae 15～20g,

Asplenium planicaule wall 12～18g, Retinervus Luffae Fructus 8～14g, Endothelium corneum Anseris domestica 5～10g, Asteriscus Pseudosciaenae 3～6g.

The process for preparing medicine processing step of the present embodiment and usage and dosage are same as in Example 1.

Embodiment 3

Herba Lysimachiae 78g, Caulis Aspidopterydis obcordatae 75g, Radix Astragali 72g, Caulis Seu Folium Euonymi Fortunei 69g, Herba Crotalariae Ferrugineae 66g,

Radix Ilicis Asprellae rattan 63g, Semen Cuscutae 60g, Radix Glycyrrhizae 57g, Herba Ecliptae 54g, Herba Cucubali japonici 50g,

Radix Angelicae Sinensis 47g, Herba goodyearae repentis 44g, Radix achyranthis asperae (Herba Achyranthis Asperae) 40g, Alectoria asiatica Du Rietz 36g, Radix Paeoniae Alba 33g,

Fructus Lycii 30g, Semen Abutili 27g, Herba Aristolochiae 24g, Rhizoma Chuanxiong 21g, clear Fructus Solani melongenae 18g,

Asplenium planicaule wall 15g, Retinervus Luffae Fructus 12g, Endothelium corneum Anseris domestica 8g, Asteriscus Pseudosciaenae 4g.

Clinical data:

1, case selection

Select urinary calculi patient 60 example that my institute accepts for medical treatment, be diagnosed as urinary calculi through imaging examinations such as B ultrasonic, X-ray film, CT.Main clinical manifestation is lower back, hypogastric region dull pain, angor or severe pain, is radiated to perineal position, frequent micturition, urgent micturition, dysurea, hematuria etc., is often accompanied by the symptoms such as Nausea and vomiting.Unilateral renal calculus 28 example, Bilateral Renal calculus 8 example, proximal ureteral calculus 10 example, distal ureteral calculi 12 example, vesical calculus 2 example in all patients.

All patients is randomly divided into two groups, treatment group 30 example, wherein male 17 example, women 13 example, age 29～64 years old, 45.8 years old mean age, the shortest person of the course of disease 2 days, elder 3 months.Matched group 30 example, wherein male 18 example, women 12 example, age 30～67 years old, 45.3 years old mean age, the shortest person of the course of disease 1 day, elder 3 months.Two groups of patient's qualifications and record of service are basically identical, without significant difference, have comparability.

2, two groups of patients all are needed to carry out ultrasonic lithotripsy in treatment by the state of an illness.Taking medicine of the present invention after treatment group patient's rubble, take after mixing it with water with boiled water half an hour ante cibum, each 1 bag, three times a day, 7 days be 1 course for the treatment of.After the ultrasonic rubble of matched group patient, give the conventional therapies such as diuresis, spasmolytic, infection, analgesia, fluid infusion the most to the ill.

3, efficacy determination:

(1) curing: clinical symptoms and sign disappear, imaging examination result display calculus is discharged, and noresidue, routine urianlysis result is normal；

(2) taking a turn for the better: clinical symptoms and sign substantially disappear or have clear improvement, imaging examination result display calculus volume-diminished or quantity significantly reduce；

(3) invalid: symptom is with treating front no significant difference.

4, result

Treatment group cure rate 60%, total effective rate 90%, matched group cure rate 40%, total effective rate 83.3%, two groups of comparitive study, difference has a statistical significance (P < 0.05), therefore treatment group is substantially better than matched group for the curative effect of primary disease.

1 liang of table group patient clinical comparitive study

Model case is illustrated:

1, Zhao's ××, man, 45 years old.This patient's two weeks comes, and often right side soreness of waist pain recurrent exerbation, accompanies little abdominal distention to ache, and hematuria, urgent micturition, frequent micturition are hard and dry.Carry out institute's inquiring, B ultrasonic shows that right kidney has the high light group of 1 0.8cm × 0.5cm, right ureter epimere has the hot spot of 1 0.6cm × 0.7cm, is diagnosed as urinary calculi, after using ultrasound wave lithotripsy in treatment, after taking 2 courses for the treatment of of Chinese medicine of the present invention, clinical symptoms is wholly absent, and the right kidney of imaging examination and right ureter calculus are the most all discharged, noresidue, routine urianlysis result is normal, fully recovers.

2, Lee's ××, female, 58 years old.Patient left side in the last few days sensation left side lumbar pain often in bed.Carry out institute's inquiring, B ultrasonic shows that left kidney has the high light group of 1 0.5cm × 0.7cm, it is diagnosed as urinary calculi, using after ultrasound wave lithotripsy in treatment, after taking 1 course for the treatment of of Chinese medicine of the present invention, clinical symptoms is wholly absent, the left renal calculus of imaging examination is the most all discharged, noresidue, routine urianlysis result is normal, fully recovers.

Urinary calculi is common disease clinically, including renal calculus, ureteral calculus, vesical calculus and calculus of urethra.Treatment is based on ultrasonic rubble at present, and after rubble, hematuria, lower abdominal pain, urodynia, lumbago shape often occurs in patient, can give the conventional therapies such as diuresis, spasmolytic, infection, analgesia, fluid infusion after usual ultrasonic rubble as required.The present invention, according to the cause of disease, suits the remedy to the case, side in Endothelium corneum Anseris domestica, Asteriscus Pseudosciaenae, clear Fructus Solani melongenae, Herba Lysimachiae, Caulis Aspidopterydis obcordatae, Herba Cucubali japonici, Radix Ilicis Asprellae rattan can heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, calculus dissolving and excreting；In side, Semen Abutili can relieving stranguria by diuresis, laxation relieving constipation；Semen Cuscutae, Fructus Lycii, Alectoria asiatica Du Rietz in side, Herba Crotalariae Ferrugineae can nourishing the kidney and liver；In side, the Radix Astragali can invigorating QI to consolidate the body surface resistance, diuresis evacuation of pus；In side, Radix Angelicae Sinensis can replenishing and activating blood；In side, the Radix Paeoniae Alba can nourishing blood to suppress the hyperactive liver, slow middle pain relieving；In side, Herba Ecliptae can cooling blood for hemostasis；Rhizoma Chuanxiong in side, Radix achyranthis asperae (Herba Achyranthis Asperae) can blood circulation promoting and blood stasis dispelling；Herba goodyearae repentis in side, Herba Aristolochiae can promoting flow of QI and blood, subduing swelling and detoxicating；Caulis Seu Folium Euonymi Fortunei in side, Asplenium planicaule wall can relaxing muscles and tendons and activating QI and blood in the collateral, hemostasis repercussive；In side, Retinervus Luffae Fructus can dredge the meridian passage, inducing diuresis to remove edema, hemostasis；In side, Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription；In side, all medicines share, nourishing the kidney and liver, vigorate qi and replenish the blood, heat-clearing and toxic substances removing, calculus dissolving and excreting, inducing diuresis for treating stranguria syndrome, promoting flow of QI and blood, hemostasis repercussive, channels sootheing and network vessel quickening, effect of reducing swelling and alleviating pain can be played altogether, damage to renal tissue when can quickly repair ultrasonic rubble, hemostasia and detumescence, reduce inflammation, waist pain-relieving, increase urine volume, lax tube chamber, tonneau water channel, thus discharge for rubble and create favorable conditions, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to urinary calculi cure rate according to clinical verification.

Claims

1. assist the instant particles as Chinese medicine of discharge after the ultrasonic rubble of urinary system, it is characterised in that raw material composition and the parts by weight of making described effective ingredient are:

The instant particles as Chinese medicine assisting discharge after the ultrasonic rubble of urinary system the most according to claim 1, it is characterised in that make described effective ingredient raw material composition and parts by weight be:

The preparation method of the most according to claims 1 to 3 instant particles as Chinese medicine assisting discharge after the ultrasonic rubble of urinary system, it is characterised in that comprise the following steps that: