CN105250555A

CN105250555A - Therapeutic drug for coronavirus infection

Info

Publication number: CN105250555A
Application number: CN201510774750.9A
Authority: CN
Inventors: 蓝本祥; 李先强
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-11-14
Filing date: 2015-11-14
Publication date: 2016-01-20

Abstract

The invention relates to a therapeutic drug for coronavirus infection, and belongs to the technical field of medicine. The therapeutic drug solves the therapeutic problem of coronaviruses and is prepared from 15 parts of chrysanthemum, 12 parts of codonopsis pilosula, 10 parts of scutellaria baicalensis, 10 parts of schizonepeta, 10 parts of cassia twigs, 10 parts of polygala tenuifolia, 10 parts of radix bupleuri, 10 parts of radix astragali, 10 parts of ligusticum wallichii, 10 parts of poria cocos, 10 parts of radix angelicae pubescentis, 3 parts of bile arisaema, 10 parts of pinellia ternate, 10 parts of radix adenophorae, 10 parts of cortex mori radicis and 7 parts of licorice roots.

Description

The medicine of coronavirus infection

Technical field

The present invention relates to a kind of medicine of coronavirus infection, particularly with the medicine that plurality of Chinese combines, belong to medicine and pharmacology technical field.

Background technology

The human diseases that coronavirus causes is respiratory system infection (comprising severe acute respiratory syndrome, SARS) mainly.The virus of this family also causes many Animal diseases.Coronavirus is one of main pathogen of adult's common cold, and childhood infection rate is higher, mainly upper respiratory tract infection, generally seldom involves lower respiratory tract.2 ~ 5 days incubation periods.Each age group all has morbidity, and child is common, and take upper respiratory tract infection as feature, minority can cause diarrhoea, bronchitis, pneumonia and hydrothorax etc.Coronavirus is single-stranded RNA virus, likeness in form corolla or corona.Pathogenesis after mainly coronavirus invades the ciliated epithelial cell on the respiratory tract surface of people, within it copies and spreads, and directly causing infected cell damage, causing local patholoic change or generation whole body toxemic symptoms.Clinical manifestation: 2 ~ 5 days incubation periods.Mainly cause upper respiratory tract infection, heating can be had, feel cold, have a headache, watery nasal discharge, pharyngalgia and cough.Most patients shows as mild, and small number of patients is medium symptom flu, and serious symptom person accounts for only a few.The course of disease 2 ~ 18 days, average one week; Minority can cause diarrhoea, bronchitis, pneumonia and hydrothorax etc.

There is mild flu in winter-spring season child, many without heating, coronavirus infection should be thought of as, inoculate human fetal trachea after making a definite diagnosis available nose, throat wash added with antibiotic to cultivate and cell culture 1 ~ 2 week, day by day check ciliary movement and cytopathy, and combine with complement and neutralizing antibody test for identification virus, or do complement fixation test and neutralizing antibody mensuration with paired sera, if there are more than 4 times rising persons to make a definite diagnosis, indirect hemagglutination test is quick, sensitive, high specificity.Diagnosis is made according to medical history, clinical manifestation and cell culture result and Evaluation of Complement Fixation Test.

Coronavirus infection there is no effective antiviral drugs at present.Ribavirin has certain effect for the infant suffering from Serious respiratory tract syncytial virus infection.It should be noted that zoopery energy teratogenesis shape, anemia of pregnant woman is forbidden.For respiratory virus infection patient, general treatment comprises pyrogenic stage and should lie up, drink more water.High heat can give physics or drug cooling; Severe headache person can oral APC (aspirin phenacetin caffeine); When asthma, cyanosis, answer oxygen supply, spasmolytic; When bronchiolitis, pneumonia occur, answer expectoration, keep airway patency, row tracheotomy if desired and human assistance are breathed; Merge heart failure person, should cardiac tonic be given; If secondary bacterial infection person, effective antibacterials should be given in time.Azauracil, ribavirin (virazole) and spiral shell diamantane (obsolete), have obvious inhibitory action to coronavirus; Vitamin C has the effect of opposing coronavirus infection.Hormone therapy is still disputable.

Summary of the invention

First coronavirus infects respiratory tract, belongs to viral, is infectious, and route of infection is by intimate contact or droplet transmission pathogen.Coronavirus infection is explained with Chinese medicine, belong to diseases caused by exogenous pathogenic factor epidemic disease poison, in invade heat-transformation, phlegm-damp stop up Sheng make pathogenic factor, also just say, there is not the result that still human external viral infection is attacked in coronavirus infection, the daily life of people is not normal, cold dim uncomfortable, reason that deficiency of vital energy and physically weak to immunocompetence is also lowly morbidity.Treatment coronavirus infection, should make combined treatment with the Chinese medicine of invigorating the spleen to benefit the lung, dispelling phlegm and eliminating dampness, heat-clearing and toxic substances removing, nourishing YIN and relieving the exterior syndrome.

The medicine of coronavirus infection combines by each Chinese medicine quality part ratio below: Flos Chrysanthemi 15 parts, Radix Codonopsis 12 parts, Radix Scutellariae 10 parts, Herba Schizonepetae 10 parts, Ramulus Cinnamomi 10 parts, Radix Polygalae 10 parts, Radix Bupleuri 10 parts, the Radix Astragali 10 parts, Rhizoma Chuanxiong 10 parts, 10 parts, Poria, Radix Angelicae Pubescentis 10 parts, Arisaema Cum Bile 3 parts, the Rhizoma Pinelliae 10 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Cortex Mori 10 parts, 7 parts, Radix Glycyrrhizae.

Analyze the property of medicine drug effect of each Chinese medicine ingredients in the medicine of coronavirus infection below one by one.Chinese medicinal chrysanthemum taste is micro-pungent, sweet, bitter, cold nature; Energy dispelling wind and heat pathogens, liver heat removing and eyesight improving, suppressing the hyperactive liver sun, removing toxic substances; For cold anemopyretic, heating is dizzy; Liver Channel has heat; The many tear of conjunctival congestion, or the hepatic and renal YIN deficiency, eyes is dim-sighted; Excessive rising of liver-YANG, dizziness and headache; Skin infection swells and ache.Radix Codonopsis is traditional tonic that China commonly uses, and has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting; There is enhancing immunity, blood vessel dilating, blood pressure lowering, improve microcirculation, strengthen the effects such as hemopoietic function.Radix Scutellariae has the effect such as heat clearing and damp drying, eliminating fire and detoxication.Herba Schizonepetae function cures mainly: deliver, and dispels the wind, treating blood disorders; Parch to black hemostasis, antibacterial, do virus.Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins, for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia.Chinese medicine polygala root is warm in nature, acrid in the mouth, hardship, enters the heart, kidney, lung meridian; To calm the nerves Fructus Alpiniae Oxyphyllae, to eliminate the phlegm, resolving depression, swell for palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, carbuncle skin ulcer.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain.Chinese medicine astragalus has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Poria detoxifies, dehumidifying, and sharp joint, cures mainly: control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, treats furuncle, carbuncle, scrofula, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain.Radix Angelicae Pubescentis, another name solely shakes grass, solely sliding, Sempervivum tectorum. and effect: dispel the wind, victory is wet, cold expelling, pain relieving. control anemofrigid-damp arthralgia.Arisaema Cum Bile function cures mainly: clearing away fire and eliminating phlegm, and relieving convulsion fixed chronic, control middle wind-phlegm fan, infantile convulsion epilepsy, phlegm-fire is breathed heavily and coughed, phlegm-accumulating vertigo.Rhizoma Pinelliae drying dampness to eliminate phlegm; Stopping nausea and vomiting by lowering the adverse flow of QI; Dissolving lump and resolving mass; Reducing swelling and alleviating pain.Radix Adenophorae (Radix Glehniae) nourishing YIN and clearing away lung-heat, expelling phlegm for arresting cough, heart tonifying, lung heat clearing away, sputum eliminating, nourishing the stomach to promote the production of body fluid.Cortex Mori is the root bark of moraceae plants Mulberry, effect: eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.Radix Glycyrrhizae is except can except coordinating the actions of various ingredients in a prescription, and the drug effect of self is not little yet; The invigorating the spleen and replenishing QI of Radix Glycyrrhizae energy, relieving spasm to stop pain, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing.

The medicine beneficial effect of the invention of coronavirus infection is: by with the viewpoint analysis coronavirus infection of Chinese medicine, belong to diseases caused by exogenous pathogenic factor epidemic disease poison, in invade heat-transformation, phlegm-damp stop up Sheng make pathogenic factor, also just say, there is not the result that still human external viral infection is attacked in coronavirus infection, the daily life of people is not normal, cold dim uncomfortable, reason that deficiency of vital energy and physically weak to immunocompetence is also lowly morbidity, take to be combined into medicine with the Chinese medicine of invigorating the spleen to benefit the lung, dispelling phlegm and eliminating dampness, heat-clearing and toxic substances removing, nourishing YIN and relieving the exterior syndrome, application for the treatment of successful.

Detailed description of the invention

The medicine of preferred embodiment to coronavirus infection makes further implementation below.

It is combine by each Chinese medicine quality ratio below that the medicine of coronavirus infection is applicable to the dosage medicine that a coronavirus patient takes: Flos Chrysanthemi 15 grams, Radix Codonopsis 12 grams, Radix Scutellariae 10 grams, Herba Schizonepetae 10 grams, Ramulus Cinnamomi 10 grams, Radix Polygalae 10 grams, Radix Bupleuri 10 grams, the Radix Astragali 10 grams, Rhizoma Chuanxiong 10 grams, 10 grams, Poria, Radix Angelicae Pubescentis 10 grams, Arisaema Cum Bile 3 grams, the Rhizoma Pinelliae 10 grams, Radix Adenophorae (Radix Glehniae) 10 grams, Cortex Mori 10 grams, 7 grams, Radix Glycyrrhizae.

The using method of the medicine of coronavirus infection: by an above-listed dosage Effect of Chinese Medicine Qing wash clean, with 1.5 the lucid yang sending up water infiltrations drench post-heating decoct half an hour, taking liquid is drunk, and within one day, takes potion dose, serve on a week as curing or effectively suppress.

Claims

1. the medicine of coronavirus infection, is characterized in that combining by each Chinese medicine quality part ratio below: Flos Chrysanthemi 15 parts, Radix Codonopsis 12 parts, Radix Scutellariae 10 parts, Herba Schizonepetae 10 parts, Ramulus Cinnamomi 10 parts, Radix Polygalae 10 parts, Radix Bupleuri 10 parts, the Radix Astragali 10 parts, Rhizoma Chuanxiong 10 parts, 10 parts, Poria, Radix Angelicae Pubescentis 10 parts, Arisaema Cum Bile 3 parts, the Rhizoma Pinelliae 10 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Cortex Mori 10 parts, 7 parts, Radix Glycyrrhizae.