CN105246917A - 生产单克隆IgA抗体的方法 - Google Patents

生产单克隆IgA抗体的方法 Download PDF

Info

Publication number
CN105246917A
CN105246917A CN201480026684.0A CN201480026684A CN105246917A CN 105246917 A CN105246917 A CN 105246917A CN 201480026684 A CN201480026684 A CN 201480026684A CN 105246917 A CN105246917 A CN 105246917A
Authority
CN
China
Prior art keywords
intestinal
iga antibody
monoclonal iga
genus
bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480026684.0A
Other languages
English (en)
Chinese (zh)
Inventor
新蔵礼子
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kansai Bunri Sogo Gakuen
Original Assignee
Kansai Bunri Sogo Gakuen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kansai Bunri Sogo Gakuen filed Critical Kansai Bunri Sogo Gakuen
Publication of CN105246917A publication Critical patent/CN105246917A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1228—Enterobacterales (O), e.g. Citrobacter (G), Serratia (G), Proteus (G), Providencia (G), Morganella (G) or Yersinia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nutrition Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201480026684.0A 2013-03-11 2014-03-10 生产单克隆IgA抗体的方法 Pending CN105246917A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2013-048365 2013-03-11
JP2013048365 2013-03-11
JP2013167120 2013-08-09
JP2013-167120 2013-08-09
PCT/JP2014/056216 WO2014142084A1 (ja) 2013-03-11 2014-03-10 モノクローナルＩｇＡ抗体の製造方法

Publications (1)

Publication Number Publication Date
CN105246917A true CN105246917A (zh) 2016-01-13

Family

ID=51536740

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480026684.0A Pending CN105246917A (zh) 2013-03-11 2014-03-10 生产单克隆IgA抗体的方法

Country Status (5)

Country Link
US (2) US9765151B2 (enExample)
EP (1) EP2995679A4 (enExample)
JP (2) JP5916946B2 (enExample)
CN (1) CN105246917A (enExample)
WO (1) WO2014142084A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109504615A (zh) * 2017-09-15 2019-03-22 深圳华大生命科学研究院 单形巨单胞菌（Megamonas funiformis）及其应用
CN110891583A (zh) * 2017-07-18 2020-03-17 学校法人庆应义塾 针对Th1细胞诱导性细菌的抗菌组合物
CN112888448A (zh) * 2018-12-07 2021-06-01 深圳华大生命科学研究院 单形巨单胞菌在预防和/或治疗代谢性疾病中的用途
CN113122507A (zh) * 2021-04-27 2021-07-16 江南大学 一种快速检测铜绿假单胞菌的双抗体夹心elisa方法
US20230202890A1 (en) * 2021-12-28 2023-06-29 Chic-Yi LIN Method for preparing agricultural products from biological sludge containing microbial cells

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014142084A1 (ja) * 2013-03-11 2014-09-18 学校法人関西文理総合学園 モノクローナルＩｇＡ抗体の製造方法
WO2014144292A2 (en) 2013-03-15 2014-09-18 Sanofi Pasteur Biologics , Llc Antibodies against clostridium difficile toxins and methods of using the same
JP7031662B2 (ja) * 2017-03-28 2022-03-08 味の素株式会社 腸内環境改善用食品
JP2021530237A (ja) 2018-07-17 2021-11-11 ウーマブス ビオメド エセアー Ｃａｍｐｙｌｏｂａｃｔｅｒの種に対する抗体
WO2022011264A2 (en) * 2020-07-10 2022-01-13 The Wistar Institute Of Anatomy And Biology Dna antibody constructs for use against rotavirus
AU2022269411A1 (en) * 2021-05-04 2023-12-21 Immunorizon Ltd. Anti-nkg2d antibodies and uses thereof
JP7425452B2 (ja) * 2021-07-01 2024-01-31 国立大学法人 東京大学 クロストリジウム・ディフィシル菌に結合する抗体
EP4364755A4 (en) * 2021-07-02 2026-02-18 Univ Tokyo COMPOSITION CONTAINING A MONOCLONAL ANTIBODY TO SUPPRESS CLOSTRIDIUM DIFFICILE BACTERIA
CN118043074A (zh) 2021-09-30 2024-05-14 伊加尔株式会社 含有单克隆抗体的组合物
EP4574840A1 (en) 2022-08-15 2025-06-25 The University of Tokyo Method for producing immunoglobulin or multimer immunoglobulin using filamentous fungus
CN120826417A (zh) 2023-03-03 2025-10-21 国立大学法人东京大学 免疫球蛋白
WO2024237217A1 (ja) * 2023-05-12 2024-11-21 国立大学法人 東京大学 クロストリジオイデス・ディフィシル菌に結合する抗体
CN117467016B (zh) * 2023-12-27 2024-03-12 北京索莱宝科技有限公司 人IgA的抗体、抗体组合及其应用
WO2025220732A1 (ja) * 2024-04-17 2025-10-23 国立研究開発法人国立循環器病研究センター 肺高血圧症の予防又は治療薬

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1381567A (zh) * 2001-04-18 2002-11-27 上海博德基因开发有限公司 一种多肽——丝氨酸羟甲基转移酶－10.56和编码这种多肽的多核苷酸

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180058863A (ko) * 2005-11-30 2018-06-01 애브비 인코포레이티드 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도
US8669353B2 (en) * 2008-05-15 2014-03-11 W. Health L.P. Process for producing milk fractions rich in secretory immunoglobulins
WO2014142084A1 (ja) * 2013-03-11 2014-09-18 学校法人関西文理総合学園 モノクローナルＩｇＡ抗体の製造方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1381567A (zh) * 2001-04-18 2002-11-27 上海博德基因开发有限公司 一种多肽——丝氨酸羟甲基转移酶－10.56和编码这种多肽的多核苷酸

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
READ M等: "Dynamic subcellular localization of isoforms of the folate pathway enzyme serine hydroxymethyltransferase(SHMT)through the erythrocytic cycle of plasmodium falciparum", 《MALARIA JOURNAL》 *
TURNER SR等: "Identification and localization of multiple forms of serine hydroxymethyltransferase in pea (Pisum sativum) and characterization of a cDNA encoding a mitochondrial isoform", 《J BIOL CHEM》 *
新蔵礼子: "腸内フローラ制御に有効な腸管IgA抗体の分離", 《ヤクルト バイオサイエンス研究財団年報》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110891583A (zh) * 2017-07-18 2020-03-17 学校法人庆应义塾 针对Th1细胞诱导性细菌的抗菌组合物
CN110891583B (zh) * 2017-07-18 2023-06-06 学校法人庆应义塾 针对Th1细胞诱导性细菌的抗菌组合物
CN109504615A (zh) * 2017-09-15 2019-03-22 深圳华大生命科学研究院 单形巨单胞菌（Megamonas funiformis）及其应用
CN112888448A (zh) * 2018-12-07 2021-06-01 深圳华大生命科学研究院 单形巨单胞菌在预防和/或治疗代谢性疾病中的用途
CN113122507A (zh) * 2021-04-27 2021-07-16 江南大学 一种快速检测铜绿假单胞菌的双抗体夹心elisa方法
US20230202890A1 (en) * 2021-12-28 2023-06-29 Chic-Yi LIN Method for preparing agricultural products from biological sludge containing microbial cells

Also Published As

Publication number Publication date
US20160039944A1 (en) 2016-02-11
EP2995679A1 (en) 2016-03-16
JPWO2014142084A1 (ja) 2017-02-16
EP2995679A4 (en) 2016-12-14
JP2016183153A (ja) 2016-10-20
US20180009906A1 (en) 2018-01-11
US9765151B2 (en) 2017-09-19
JP5916946B2 (ja) 2016-05-11
WO2014142084A1 (ja) 2014-09-18

Similar Documents

Publication Publication Date Title
CN105246917A (zh) 生产单克隆IgA抗体的方法
US11730772B2 (en) Lipopolysaccharide-regulated enteric bacteria and use thereof
JP7405386B2 (ja) クロストリジウム・ディフィシル菌に結合する抗体
JP6876627B2 (ja) 必要とする対象に飽満感を誘発し満腹感を持続させる医薬組成物および食品組成物
EP4364755A1 (en) Monoclonal antibody-containing composition for suppressing clostridium difficile bacteria
EP3560514A1 (en) Hypothermia ameliorating agent
WO2023219175A1 (ja) 炎症性腸疾患（ｉｂｄ）を治療または診断する方法および組成物
US20250051426A1 (en) Composition containing monoclonal antibody
JP7760200B2 (ja) 免疫グロブリン
WO2024237217A1 (ja) クロストリジオイデス・ディフィシル菌に結合する抗体
WO2025134928A1 (ja) 結腸直腸がんを治療するための組成物
WO2025225737A1 (ja) 微生物と抗体の組み合わせおよび使用
WO2025220732A1 (ja) 肺高血圧症の予防又は治療薬

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right

Effective date of registration: 20170316

Address after: Kanagawa, Japan

Applicant after: Kurid Limited by Share Ltd

Address before: Shiga

Applicant before: KANSAI BUNRI SOGO GAKUEN

TA01 Transfer of patent application right
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20160113

WD01 Invention patent application deemed withdrawn after publication