CN105194592B - Clear numbness Chinese medicine composition and preparation method thereof - Google Patents
Clear numbness Chinese medicine composition and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a kind of clear numbness Chinese medicine compositions, to treat rheumatism by way of direct current current iontophoresis.The effective component of clear numbness Chinese medicine composition according to the present invention is made of following bulk pharmaceutical chemicals: Radix Angelicae Sinensis, radix achyranthis bidentatae, radix paeoniae rubra, Radix Angelicae Pubescentis, Sargent gloryvine, ginger, olibanum, myrrh, aconiti preparata,radix, monkshood, the tuber of pinellia, Cortex Eucommiae, psoralea corylifolia and Herba Cistanches.The present invention also provides the preparation method of above-mentioned clear numbness Chinese medicine composition and direct current current iontophoresis systems.
Description
Technical field
The present invention relates to a kind of clear numbness Chinese medicine compositions and preparation method thereof, more particularly to one kind to be used for iontophoresis
Chinese medicine composition of rheumatism and preparation method thereof.
Background technique
Chinese medicine so-called " rheumatism " refer to human body machine table and channels and collaterals because caused by sense wind, cold, wet, heat etc. with limbs joint and
DOMS, numbness, weigh, joint stuffiness or even arthrocele are scorching hot etc. be primary symptom a kind of disease.Clinically have gradual
Or the characteristics of repeated relapsing.Main pathogenesis is that the resistance of qi and blood numbness is obstructed, and tendon and vessel joint is lost caused by supporting.The wind of modern medicine
Wet, rheumatic arthritis, rheumatoid arthritis, Osteoarthritis, gout, Raynand's disease, ankylosing spondylitis, sciatic nerve
Bitterly, Osteoarthritis, osteoproliferation etc. degenerative disease belong to " rheumatism " scope.
For western medical treatment rheumatism to control acute attack, based on Long-term taking medicine, common oral drugs have certain analgesic effect,
But larger, easy recurrence after drug withdrawal is stimulated stomach；Glucocorticoid medicine can only short-period used, long-term use can reduce pass
Immunity is saved, aggravates the state of an illness instead.
In contrast, Chinese medicine has accumulated experience more abundant in terms for the treatment of rheumatism, currently becomes clinical research
Hot spot.Wherein, in such a way that external medicine composition local penetration is entered aura position by ion-introduction therapy, not only there is needle
Improve local drug concentration to property, rapid-action, good effect, and since drug is absorbed without stomach, so substantially without
Side effect, total dosage are also only ten parts of oral drugs.
However, at present there are following several respects in the pharmaceutical admixtures of existing iontophoresis rheumatism:
First is that pharmaceutical formulation falls behind.Although being all to belong to Chinese medicine " rheumatism " therapeutic domain, many pharmaceutical formulations can only needle
It is effective to a handful of position, clinically different parts are carried out with treatment and needs to prepare different pharmaceutical compositions, gives patient
Trouble is all caused with doctor.
Second is that the preparation means of pharmaceutical composition fall behind.Conventional ion imports the preparation of pharmaceutical composition generally with decocting method
Based on, this method is stringent to time requirement, but due to pharmaceutical composition complicated composition, not can guarantee every kind of drug and be attained by
Optimal decocting time.In addition, this mode is larger to Chinese medicine component damage itself, the Chinese medicine liquid active constituent content of extraction
It is lower, therapeutic effect is influenced, and be difficult to save for a long time under normal conditions.
Third is that the concrete operation method of electro-ionic osmosis falls behind.When Traditional DC current iontophoresis, anode medicine pad and cathode medicine
Pad is different using drug, it is necessary to while two kinds of medical fluids are prepared, positively charged medicine ion is penetrated from anode medicine pad, electronegative medicine
Object ion is penetrated from cathode medicine pad, and anode medicine pad and cathode medicine pad are placed in privileged site separated by a distance when operation,
As shown in FIG. 1A and 1B, when being respectively traditional lumbar treatment and cervical vertebra treatment medicine pad placement schematic diagram.This operation side
Method requires electric current to reach some strength (usually 8mA or more) to obtain preferable therapeutic effect, but heavy current is to skin irritatin
It is very big, and specific operation process is more complex, and larger to skin irritatin, most patients are difficult to receive continuously to control for a long time
It treats, affects curative effect.
Although in addition, also proposed the herbal ion penetration composition of some certain type rheumatisms for the treatment of at present, totally
Apparently, there are still various undesirable problem, technical staff is still being continually striving to thus, it is desirable to be able to develop a kind of simultaneous
The improved clear numbness Chinese medicine composition for having many advantages, such as high-efficient easy, the simple, convenient storage of preparation.
Summary of the invention
To solve the above problems, the invention proposes a kind of clear numbness Chinese medicine composition, it can be to pass through direct current electron ion
The mode of importing treats rheumatism.
The effective component of clear numbness Chinese medicine composition according to the present invention can be made of following bulk pharmaceutical chemicals: Radix Angelicae Sinensis, radix achyranthis bidentatae are red
Chinese herbaceous peony, Radix Angelicae Pubescentis, Sargent gloryvine, ginger, olibanum, myrrh, aconiti preparata,radix, monkshood, the tuber of pinellia, Cortex Eucommiae, psoralea corylifolia and Herba Cistanches.
Preferably, the effective component of the clear numbness Chinese medicine composition can be prepared from the following raw materials in parts by weight: Radix Angelicae Sinensis
20-60, radix achyranthis bidentatae 20-60, radix paeoniae rubra 20-60, Radix Angelicae Pubescentis 20-60, Sargent gloryvine 10-40, ginger 40-80, olibanum 15-30, myrrh 15-30,
Aconiti preparata,radix 8-20, monkshood 15-30, tuber of pinellia 30-80, Cortex Eucommiae 25-60, psoralea corylifolia 25-60 and Herba Cistanches 25-60.
Above-mentioned Chinese medicine composition side's solution is as follows: Radix Angelicae Sinensis is sweet in flavor, pungent, warm-natured, returns liver, the heart, the spleen channel, function replenishing and activating blood, tune
Meridian and relieving pain, cures mainly the deficiency of blood, stasis, and blood is trembled with fear all pains, traumatic injury, the diseases such as rheumatic arthralgia；Radix achyranthis bidentatae bitter sweet acid, it is mild-natured.Return liver, kidney
Through function blood circulation, nourishing liver and kidney, strengthening the bones and muscles, cures mainly lumbago due to the kidney deficiency and long numbness soreness of waist and knee joint is out of strength；Radix paeoniae rubra bitter, cold nature,
Return liver warp, function clearing heat and cooling blood, removing blood stasis and acesodyne cure mainly traumatic injury；Radix Angelicae Pubescentis acrid flavour, it is bitter, it is warm-natured, return liver, kidney, bladder meridian, function
The timid wind dehumidifying of energy, relieving exterior syndrome and dispelling cold cure mainly wind-cold-dampness arthralgia, waist and knee acid weight pain；Sargent gloryvine bitter, it is mild-natured, return large intestine channel, function heat-clearing
Removing toxic substances, promoting blood circulation and stopping pain cure mainly traumatic injury, rheumatic arthralgia；Ginger acrid flavour, warm-natured, return lung, spleen, stomach meridian.Function pungent-warm surname dissipate,
Timid wind, dissipating cold, cures mainly coldness and pain in the epigastrium, solves the poison of all medicines；Frankincense taste is arduous, warm-natured, returns liver, the heart, the spleen channel, and function blood-activating and qi-promoting stops
Bitterly, all pains of congestion blood block are cured mainly；Myrrh is bitterly, mild-natured, return heart, liver, the spleen channel, and it is stagnant to cure mainly all stasis of bloods for function promoting blood circulation and stopping pain
The all pains of trusted subordinate, rheumatic arthralgia；Aconiti preparata,radix acrid flavour is bitter, property heat, toxic, return heart, liver, kidney, the spleen channel, the timid wind dehumidifying of function, Wen Jingzhi
Bitterly, wind-cold-dampness arthralgia, joint-running pain are cured mainly；Monkshood acrid flavour, sweet, property heat, toxic, return heart, kidney, the spleen channel, function mends fire supporing yang, cold dispelling
Analgesic, cures mainly arthritis disease etc.；Tuber of pinellia acrid flavour, warm-natured, toxic, return lung, spleen, stomach meridian, function is eliminating dampness and eliminating phlegm, and dissolving lump and resolving mass cures mainly
Damp phlegm is trembled with fear phlegm, gall subcutaneous nodule；Cortex Eucommiae is sweet in flavor, warm-natured, returns liver, kidney channel, and function tonifies the liver and kidney, and strengthening the muscles and bones cures mainly soreness of waist and knee joint,
Muscles and bones is withered soft；Psoralea corylifolia acrid flavour, it is bitter, it is warm-natured, return kidney, the spleen channel, function tonifying kidney and strengthening yang cures mainly waist and knee crymodynia；Herba Cistanches are sweet in flavor,
It is salty, it is warm-natured, return kidney, large intestine channel, function tonifying kidney and benefiting sperm cures mainly waist and knee crymodynia, and muscles and bones is powerless.
The present invention also provides the preparation methods of above-mentioned clear numbness Chinese medicine composition, and the method may include following steps:
(1) each bulk pharmaceutical chemicals mixing in the clear numbness Chinese medicine composition is weighed, with immersion 8-18 hours of 1000-3000 milliliters of pure water
(preferably 12 hours), then (preferably 12 is small for addition 1000-3000 milliliters of 55-65 degree white wine immersion 8-18 hours into soak
When), it then will impregnate gained medical fluid and pour out storage；(2) pure water is added again in the bulk pharmaceutical chemicals after step (1) is impregnated to impregnate
8-18 hours (preferably 12 hours), add 1000-3000 milliliters of 55-65 degree white wine immersion 8-18 hours (preferably 12 hours)；
(3) medical fluid obtained by step (1) and (2) is merged, continues to impregnate bulk pharmaceutical chemicals 24-120 hours and be poured out after (preferably 72 hours), is filtered
It is spare.Wherein, it is contemplated that effect and time cost, at 12 hours, the time of step (3) existed the soaking time of step (1) and (2)
72 hours are best.
The preparation method of clear numbness Chinese medicine composition of the invention is that inventor summarizes in practice in more than 30 years and obtains,
According to the principle that the characteristics of herbal ion penetration medical fluid, utilize " water extracts the alcohol precipitation method ", using " pure water " and " white wine "
Optimum solvent combines to extract the effective component in bulk pharmaceutical chemicals.Compared to traditional " decocting method ", using of the invention, " water is mentioned
Take the alcohol precipitation method " preparation Chinese medicine composition electro-ionic osmosis liquid have the advantage that one, effective component purity is high, medical fluid retain
The effective components such as alkaloid salts, glycoside, amino acid, acylate, and eliminate protein, mucilaginous substance, grease, natural gum etc.
Impurity；Two, the effective component in Chinese medicine is more desirably remained, the biology for having thermal sensitivity will not be especially destroyed in Chinese medicine and live
Property component；Three, contain alcoholic content in medical fluid, bactericidal effect can be played, be easy to store, in practice it has proved that, this method preparation
Chinese medicine composition store 18 months and all undergo no deterioration at normal temperature.
Preferably, above-mentioned clear numbness Chinese medicine composition can be in the form of electro-ionic osmosis liquid, to facilitate direct use, but this hair
It is bright to be not limited to this.It will be understood by those skilled in the art that can also be in the way of generally in the art by above-mentioned clear numbness Chinese medicine group
It closes object and solid form, such as particle form is further made, to facilitate storage and transport, when use is dissolved again.
In use, the medical fluid of above-mentioned clear numbness Chinese medicine composition is impregnated full medicine pad, which is placed on lesions position,
For anode upper, the importing of direct current herbal ion penetration instrument is can be used under in cathode, so that medicine ion penetrates the through disease of skin
Stove is to play curative effect.
Therefore, the present invention also provides a kind of direct current current iontophoresis system of clear numbness Chinese medicine composition, the system can
To include: the medicine pad impregnated with above-mentioned clear numbness Chinese medicine composition and direct current herbal ion penetration instrument, wherein the medicine pad is point
For upper and lower twoth area, anode of the upper area to be inserted into the direct current herbal ion penetration instrument, lower area is to be inserted into the direct current
The cathode of herbal ion penetration instrument has physics partition, so that the direct current Chinese medicine between the upper area and the lower area
It is not contacted between the anode and cathode of ion introducing apparatus.
Medicine pad can be designed to growth 15cm for example, see shown in Fig. 2 as a currently preferred embodiment,
Wide 13cm is separated in the central portion of length with sewer together, so that (left side is upper to twoth area up and down when forming use in Fig. 2
Area, right side are lower area).In use, (respectively lumbar treatment and when cervical vertebra treatment medicine pad of the invention as shown in Figure 3A and Figure 3B
Placement schematic diagram), chloride plate is inserted into upper area's pocket, cathode stereotype is inserted into lower area's pocket, and the two poles of the earth are not in contact,
To be saturated with after medical fluid medicine pad and be put in body foci position in such a way that upper, cathode is under by anode, connect direct current Chinese medicine from
Sub- introducing apparatus adjusts current strength in the range of 2.5-3.5mA, can start to treat and obtain preferable effect.General is straight
Galvanic electricity herbal ion penetration instrument be it is commercially available on the market, as Shantou City, Guangdong Province medical equipment Co., Ltd., Factory produce
DL-ZII galvanofaradism apparatus.
Compared to traditional direct current Chinese medicine current iontophoresis system, since anode medicine pad and cathode medicine pad will be respectively using not
With drug and the different parts of body are individually positioned in, therefore anode medicine pad and cathode medicine pad are also required to be fabricated separately.In use, example
Such as, when waist is treated, anode medicine pad is generally placed on waist Ashi Point, cathode medicine pad is placed on gastrocnemius；When neck is treated,
Anode medicine pad is generally placed on neck Ashi Point, cathode medicine pad is placed on scapular region.Since anode medicine pad and cathode medicine pad are put
It puts position to be separated by far, utilizes human-body conduction again, the intensity of electric current usually requires to be arranged in what 8mA or more can be only achieved
Therapeutic effect, still, current strength biggish in this way cause skin allergy and uncomfortable sometimes, or even patient is caused to be difficult to
Long-continued treatment is endured, curative effect is seriously affected.Using direct current current iontophoresis system of the invention, can well solve
The above problem.
To sum up, clear numbness Chinese medicine composition of the invention and its preparation and application are inventors in nearly 30 years clinics
Grope made of summary for a long time in practice, relative to existing technology, the present invention has the advantage that
A. the clear selected Chinese medicine preparation of numbness Chinese medicine composition of the invention goes numerous to deposit letter, the best drug of retention and conjunction
Compatibility is managed, so that folk prescription can correspond to all kinds of rheumatisms, by clinical practice, patient can not only control the state of an illness quickly, and
And long-term effect is excellent, recurrence rate is extremely low, and therapeutic effect is ideal；
B. the preparation method of the clear numbness Chinese medicine composition is original creation, and the medical fluid active constituent content of extraction is high, conventional strip
It saves 18 months and undergoes no deterioration under part, be readily transported, lay in, and concrete operations are easy to learn, convenient for promoting；
When c. using the direct current current iontophoresis systematic treating of clear numbness Chinese medicine composition of the invention, anode and cathode medication is identical
And be spaced closely together, conducive to the importing of effective ingredient, and small, process health is stimulated patient skin, it is low-cost, make patient
It is easy to receive continuous treatment for a long time, improves curative effect.
Other features and advantages of the present invention will be listed in the following description or those skilled in the art are reading this
Some other feature and advantage will be obviously realized after practicing after specification or to the present invention.
Detailed description of the invention
Figure 1A and Figure 1B is the direct current herbal ion penetration medicine pad and its placement schematic diagram of the prior art；
Fig. 2 is direct current herbal ion penetration medicine pad floor map of the invention；
Fig. 3 A and Fig. 3 B are the placement schematic diagram of direct current herbal ion penetration medicine pad of the invention.
Specific embodiment
In order to keep the objectives, technical solutions, and advantages of the present invention clearer, below by way of specific embodiment to the present invention
It is further detailed.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to limit
Determine protection scope of the present invention.
Embodiment 1:
Radix Angelicae Sinensis 40g, radix achyranthis bidentatae 40g, radix paeoniae rubra 40g, Radix Angelicae Pubescentis 40g, Sargent gloryvine 20g, ginger 60g, olibanum 20g, myrrh 20g are weighed,
Aconiti preparata,radix 10g, monkshood 20g, tuber of pinellia 60g, Cortex Eucommiae 40g, psoralea corylifolia 40g, Herba Cistanches 40g, mixing.With 2000 milliliters of pure water loggings
Bubble 12 hours, adds 2000 milliliters of 55 degree of soaking in Chinese liquor 12 hours, then will impregnate gained medical fluid and pours out storage；After steeping
Bulk pharmaceutical chemicals in 2000 milliliters of pure water be added again impregnate 12 hours, add 2000 milliliters of 55 degree of soaking in Chinese liquor 12 hours；
Gained medical fluid will be impregnated twice to merge, and be continued to pour out after impregnating bulk pharmaceutical chemicals 72 hours, be filtered spare.
Embodiment 2
Radix Angelicae Sinensis 50g, radix achyranthis bidentatae 50g, radix paeoniae rubra 50g, Radix Angelicae Pubescentis 50g, Sargent gloryvine 25g, ginger 70g, olibanum 25g, myrrh 25g are weighed,
Aconiti preparata,radix 15g, monkshood 25g, tuber of pinellia 70g, Cortex Eucommiae 50g, psoralea corylifolia 50g, Herba Cistanches 50g, mixing.Remaining preparation method is the same as embodiment 1.
Embodiment 3
Radix Angelicae Sinensis 40g, radix achyranthis bidentatae 50g, radix paeoniae rubra 60g, Radix Angelicae Pubescentis 60g, Sargent gloryvine 20g, ginger 60g, olibanum 25g, myrrh 25g are weighed,
Aconiti preparata,radix 15g, monkshood 25g, tuber of pinellia 60g, Cortex Eucommiae 50g, psoralea corylifolia 50g, Herba Cistanches 50g, mixing.Remaining preparation method is the same as embodiment 1.
Embodiment 4
Radix Angelicae Sinensis 60g, radix achyranthis bidentatae 60g, radix paeoniae rubra 60g, Radix Angelicae Pubescentis 60g, Sargent gloryvine 30g, ginger 80g, olibanum 30g, myrrh 30g are weighed,
Aconiti preparata,radix 20g, monkshood 30g, tuber of pinellia 80g, Cortex Eucommiae 60g, psoralea corylifolia 60g, Herba Cistanches 60g, mixing.Remaining preparation method is the same as embodiment 1.
Clinical test example
320 rheumatism patients of clinical statistics carry out the feelings of iontophoresis using clear numbness Chinese medicine composition of the invention
Condition.Patient age is between 16 years old to 78 years old, wherein 150 people of male, and women 170.Wherein clinical diagnosis is prominent with lumber ertebral disc
80 people out, 80 people of cervical spondylosis, 80 people of degenerative knee, 40 people of caput femoris necrosis, 30 people of rheumatoid do not have diagnosis to come to a conclusion
10 people of rheumatism patient.
The medical fluid for taking above-described embodiment 1-4 to prepare respectively, sufficiently immersion medicine pad, are put in sore spot, using Shantou City, Guangdong Province
The DL-ZII galvanofaradism apparatus of medical equipment Co., Ltd., Factory production, carries out iontophoresis, adjusts current strength and exists
Between 2.5-3.5mA, treatment 30 minutes, are treated 1 time, 10 days as a treatment course daily every time, are rested two days between each course for the treatment of,
Patient's recovery situation after 12 courses for the treatment of is observed, curative effect statistics is as shown in table 1 below:
Table 1
Its standard of curative effect evaluation is as follows:
Cure: the classical symptoms such as pain, numbness are completely disappeared or are disappeared substantially, no any discomfort sense；
Effective: the classical symptoms such as pain, numbness are obviously improved, accidental discomfort, but on life substantially without influence；
Effective: the classical symptoms such as pain, numbness are improved, but still when have presence；
Invalid: symptom is not improved.
Seen from table 1, it is quite high to carry out iontophoresis method cure rate to clear numbness Chinese medicine composition of the invention.
Clinical typical case
Ma, female suffered from the protrasion of the lumbar intervertebral disci come 65 years old when treating, and ct shows that L4-L5 charges into 7 milli of canalis spinalis afterwards to the left
Rice, left leg is numb, and muscular atrophy is treated using the clear numbness Chinese medicine composition of embodiment 2, left after three courses for the treatment of (30 days)
Leg feeling of numbness disappears substantially, and after the systematic treating of 12 courses for the treatment of (120 days), left leg muscle restores normal, and clinical symptoms disappear,
Follow-up 7 years without recurrence.
Cai so-and-so, male, come 38 years old when treating, cervical vertebra curve was counter bends for the display of x mating plate, and c3-c6 osteoproliferation is obvious, readme disease
Shape both hands are numb, the vomiting of head dizziness, insomnia.It is treated using the clear numbness Chinese medicine composition of embodiment 1, three courses for the treatment of (30
It) after, both hands feeling of numbness disappears substantially, and head dizziness vomiting number is reduced, and insomnia improves, and what it is through 12 courses for the treatment of (120 days) is
It rules after treating, clinical symptoms completely disappear.Follow-up 5 years without recurrence.
Lee, female, come 58 years old when treating, left knee hydrops oedema, right knee pain slightly swelling, using the clear numbness of embodiment 4
Chinese medicine composition is treated, and a course for the treatment of (10 days) afterwards obviously subside by double knee swelling, three course for the treatment of (30 days) rear left knee hydrops
Oedema completely disappears, and right knee pain and swelling symptom disappears.5 years rear left knees of follow-up have pain, treat course for the treatment of (10 days) health afterwards
It is multiple.
The foregoing is merely the preferred embodiment of the present invention, are not intended to limit the invention, all in spirit of the invention
With any modifications, equivalent replacements, and improvements made within principle etc., should all be included in the protection scope of the present invention.
Claims (6)
1. a kind of clear numbness Chinese medicine composition for electro-ionic osmosis, which is characterized in that the clear numbness Chinese medicine composition it is effective at
Divide and is prepared from the following raw materials in parts by weight: Radix Angelicae Sinensis 20-60, radix achyranthis bidentatae 20-60, radix paeoniae rubra 20-60, Radix Angelicae Pubescentis 20-60, Sargent gloryvine 10-40,
Ginger 40-80, olibanum 15-30, myrrh 15-30, aconiti preparata,radix 8-20, monkshood 15-30, tuber of pinellia 30-80, Cortex Eucommiae 25-60, psoralea corylifolia
25-60 and Herba Cistanches 25-60.
2. the clear numbness Chinese medicine composition according to claim 1 for electro-ionic osmosis, wherein the clear numbness Chinese medicine composition
For clear numbness herbal ion penetration liquid.
3. the preparation method of the clear numbness Chinese medicine composition according to any one of claim 1 to 2 for electro-ionic osmosis,
It is characterized in that, the described method comprises the following steps: (1) weighing each bulk pharmaceutical chemicals mixing in the clear numbness Chinese medicine composition, use is pure
1000-3000 milliliters of water purification immersion 8-18 hours, then 1000-3000 milliliters of immersion 8- of 55-65 degree white wine are added into soak
18 hours, it then will impregnate gained medical fluid and pour out storage；(2) pure water is added again in the bulk pharmaceutical chemicals after step (1) is impregnated
It impregnates 8-18 hours, adds immersion 8-18 hours of 1000-3000 milliliters of 55-65 degree white wine；It (3) will be obtained by step (1) and (2)
Medical fluid merges, and continues to pour out after impregnating bulk pharmaceutical chemicals 24-120 hours, filter spare.
4. the preparation method of the clear numbness Chinese medicine composition according to claim 3 for electro-ionic osmosis, wherein step (1) and
Soaking time in step (2) is 12 hours.
5. the preparation method of the clear numbness Chinese medicine composition according to claim 3 or 4 for electro-ionic osmosis, wherein step
(3) soaking time in is 72 hours.
6. a kind of direct current of the clear numbness Chinese medicine composition according to any one of claim 1 to 2 for electro-ionic osmosis
Electro-ionic osmosis system, which is characterized in that the system comprises: in the medicine pad and direct current with the clear numbness Chinese medicine composition dipping
Medicine ion introducing apparatus, wherein the medicine pad is divided into twoth area up and down, upper area is to be inserted into the direct current herbal ion penetration instrument
Anode, cathode of the lower area to be inserted into the direct current herbal ion penetration instrument have object between the upper area and the lower area
Reason partition, so that not contacted between the anode and cathode of the direct current herbal ion penetration instrument.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410281187.7A CN105194592B (en) | 2014-06-20 | 2014-06-20 | Clear numbness Chinese medicine composition and preparation method thereof |
| HK16102834.8A HK1214770A1 (en) | 2014-06-20 | 2016-03-11 | Chinese medicinal composition for treating arthromyodynia and preparation method thereof |
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| CN201410281187.7A CN105194592B (en) | 2014-06-20 | 2014-06-20 | Clear numbness Chinese medicine composition and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1090195A (en) * | 1993-11-17 | 1994-08-03 | 中国航空工业总公司第六○五研究所 | Medicine for curing comedo |
| CN102600327A (en) * | 2012-03-06 | 2012-07-25 | 爨新德 | Ostealgia treating capsule |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201064622Y (en) * | 2007-04-29 | 2008-05-28 | 西藏宇妥藏药研究有限公司 | Ion leading-in medicine label convenient for storing and carrying |
| CN103372183B (en) * | 2012-04-16 | 2015-06-03 | 冯娜 | Pharmaceutical composition for treating cervical vertebra and lumbar vertebra diseases |
-
2014
- 2014-06-20 CN CN201410281187.7A patent/CN105194592B/en active Active
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2016
- 2016-03-11 HK HK16102834.8A patent/HK1214770A1/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1090195A (en) * | 1993-11-17 | 1994-08-03 | 中国航空工业总公司第六○五研究所 | Medicine for curing comedo |
| CN102600327A (en) * | 2012-03-06 | 2012-07-25 | 爨新德 | Ostealgia treating capsule |
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| HK1214770A1 (en) | 2016-08-05 |
| CN105194592A (en) | 2015-12-30 |
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