CN104306942A - Medicine for auxiliary treatment on cervical spondylosis - Google Patents
Medicine for auxiliary treatment on cervical spondylosis Download PDFInfo
- Publication number
- CN104306942A CN104306942A CN201410595570.XA CN201410595570A CN104306942A CN 104306942 A CN104306942 A CN 104306942A CN 201410595570 A CN201410595570 A CN 201410595570A CN 104306942 A CN104306942 A CN 104306942A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- medicine
- cervical spondylosis
- auxiliary treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 56
- 206010041591 Spinal osteoarthritis Diseases 0.000 title claims abstract description 42
- 208000036319 cervical spondylosis Diseases 0.000 title claims abstract description 41
- 208000005801 spondylosis Diseases 0.000 title claims abstract description 41
- 229940079593 drug Drugs 0.000 title claims description 18
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 16
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 241000628997 Flos Species 0.000 claims description 16
- 241001057584 Myrrha Species 0.000 claims description 15
- 210000000582 semen Anatomy 0.000 claims description 15
- 239000007788 liquid Substances 0.000 claims description 13
- 238000002360 preparation method Methods 0.000 claims description 8
- 239000000706 filtrate Substances 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 3
- 238000009472 formulation Methods 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 239000003826 tablet Substances 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 2
- 208000002193 Pain Diseases 0.000 abstract description 19
- 230000036407 pain Effects 0.000 abstract description 18
- 208000024891 symptom Diseases 0.000 abstract description 15
- 230000000694 effects Effects 0.000 abstract description 11
- 208000002173 dizziness Diseases 0.000 abstract description 10
- 208000004044 Hypesthesia Diseases 0.000 abstract description 6
- 208000034783 hypoesthesia Diseases 0.000 abstract description 6
- 231100000862 numbness Toxicity 0.000 abstract description 6
- 240000007311 Commiphora myrrha Species 0.000 abstract description 3
- 244000144730 Amygdalus persica Species 0.000 abstract description 2
- 241000382455 Angelica sinensis Species 0.000 abstract description 2
- 244000020518 Carthamus tinctorius Species 0.000 abstract description 2
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract description 2
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract description 2
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract description 2
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract description 2
- 241000195954 Lycopodium clavatum Species 0.000 abstract description 2
- 244000273928 Zingiber officinale Species 0.000 abstract description 2
- 235000006886 Zingiber officinale Nutrition 0.000 abstract description 2
- 235000008397 ginger Nutrition 0.000 abstract description 2
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 2
- 241000758794 Asarum Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 18
- 210000004369 blood Anatomy 0.000 description 17
- 239000000796 flavoring agent Substances 0.000 description 12
- 235000019634 flavors Nutrition 0.000 description 12
- 239000012567 medical material Substances 0.000 description 12
- 201000010099 disease Diseases 0.000 description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 9
- 208000006820 Arthralgia Diseases 0.000 description 7
- 206010019233 Headaches Diseases 0.000 description 7
- 231100000869 headache Toxicity 0.000 description 7
- 206010062717 Increased upper airway secretion Diseases 0.000 description 6
- 235000009508 confectionery Nutrition 0.000 description 6
- 210000003414 extremity Anatomy 0.000 description 6
- 208000026435 phlegm Diseases 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 6
- 201000000736 Amenorrhea Diseases 0.000 description 5
- 206010001928 Amenorrhoea Diseases 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 5
- 210000001015 abdomen Anatomy 0.000 description 5
- 231100000540 amenorrhea Toxicity 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 208000014674 injury Diseases 0.000 description 5
- 210000003205 muscle Anatomy 0.000 description 5
- 235000019616 numbness Nutrition 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- 201000005671 spondyloarthropathy Diseases 0.000 description 5
- 208000025747 Rheumatic disease Diseases 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000000552 rheumatic effect Effects 0.000 description 4
- 238000010792 warming Methods 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 208000008454 Hyperhidrosis Diseases 0.000 description 3
- 208000019255 Menstrual disease Diseases 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 239000005720 sucrose Substances 0.000 description 3
- 210000001364 upper extremity Anatomy 0.000 description 3
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 241001289295 Asarum sieboldii Species 0.000 description 2
- 208000008035 Back Pain Diseases 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- 208000005171 Dysmenorrhea Diseases 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 241001278898 Glycyrrhiza inflata Species 0.000 description 2
- 241000800405 Spatholobus suberectus Species 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 208000019804 backache Diseases 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 238000007596 consolidation process Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000007850 degeneration Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 208000013219 diaphoresis Diseases 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000002085 persistent effect Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 208000004371 toothache Diseases 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 230000008736 traumatic injury Effects 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 240000000031 Achyranthes bidentata Species 0.000 description 1
- 235000011446 Amygdalus persica Nutrition 0.000 description 1
- 206010002027 Amyotrophy Diseases 0.000 description 1
- 241001254604 Angelica pubescens Species 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 241000758795 Aristolochiaceae Species 0.000 description 1
- 241001472196 Asarum heterotropoides Species 0.000 description 1
- 208000012639 Balance disease Diseases 0.000 description 1
- 206010005963 Bone formation increased Diseases 0.000 description 1
- 241000208229 Burseraceae Species 0.000 description 1
- 241000345998 Calamus manan Species 0.000 description 1
- 244000080208 Canella winterana Species 0.000 description 1
- 235000008499 Canella winterana Nutrition 0.000 description 1
- 206010008334 Cervicobrachial syndrome Diseases 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 235000021511 Cinnamomum cassia Nutrition 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000125183 Crithmum maritimum Species 0.000 description 1
- 208000019505 Deglutition disease Diseases 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 206010016807 Fluid retention Diseases 0.000 description 1
- 240000008917 Glycyrrhiza uralensis Species 0.000 description 1
- 235000000554 Glycyrrhiza uralensis Nutrition 0.000 description 1
- 206010019705 Hepatic pain Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 206010051326 Ligament calcification Diseases 0.000 description 1
- 241000927897 Lycopodium japonicum Species 0.000 description 1
- 206010028372 Muscular weakness Diseases 0.000 description 1
- 206010052904 Musculoskeletal stiffness Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 206010029216 Nervousness Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 244000236658 Paeonia lactiflora Species 0.000 description 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 240000002381 Prunus davidiana Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010037714 Quadriplegia Diseases 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 206010062104 Renal mass Diseases 0.000 description 1
- 241001180873 Saposhnikovia divaricata Species 0.000 description 1
- 201000001880 Sexual dysfunction Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000001871 Tachycardia Diseases 0.000 description 1
- 206010043376 Tetanus Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000019636 bitter flavor Nutrition 0.000 description 1
- 210000003461 brachial plexus Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 231100000880 dysequilibrium Toxicity 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 206010016766 flatulence Diseases 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000003447 ipsilateral effect Effects 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 230000036473 myasthenia Effects 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 235000012950 rattan cane Nutrition 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 208000009146 rhinoscleroma Diseases 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 210000001991 scapula Anatomy 0.000 description 1
- 108010048734 sclerotin Proteins 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 231100000872 sexual dysfunction Toxicity 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 201000009890 sinusitis Diseases 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 208000026843 stiff neck Diseases 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000002889 sympathetic effect Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 208000029761 vertebral disease Diseases 0.000 description 1
- 239000001841 zingiber officinale Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicine for auxiliary treatment on cervical spondylosis, belonging to the technical field of traditional Chinese medicines. The medicine is prepared from the following traditional Chinese medicines in parts by weight: 3-12 parts of carthamus tinctorius, 3-12 parts of radix angelicae tuhuo, 5-16 parts of angelica sinensis, 5-16 parts of radix paeoniae alba, 2-9 parts of liquorice, 3-7 parts of peach kernels, 3-7 parts of radix achyranthis bidentatae, 2-9 parts of myrrh, 1-7 parts of cassia twig, 2-8 parts of ginger, 3-7 parts of radix saposhnikoviae divaricatae, 3-10 parts of lycopodium clavatum, 0.5-2.5 parts of asarum sieboldi and 8-15 parts of caulis spatholobi. The medicine disclosed by the invention can treat symptoms such as pain, numbness and dizziness caused by cervical vertebra discomfort, can treat both symptoms and causes, and is long-lasting in effect, free of side effect and remarkable in curative effect.
Description
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of medicine for auxiliary treatment cervical spondylosis.
Background technology
Cervical spondylosis is commonly encountered diseases and the frequently-occurring disease of middle-aged and elderly people, and especially above person is common 50-60 year.Once had medical research to show, life-span of people should more than 120 years old, but vertebra problem allows the lost of life 1/3rd.Therefore, vertebra is otherwise known as " the second life line of human body ".Along with the modern times working method crowd that bows increases, widely using of computer, air-conditioning, people bend neck and constantly increased by the wet opportunity of wind and cold, cause the prevalence of cervical spondylosis constantly to rise, and age of onset constantly shift to an earlier date.2002 " China's teenager cervical vertebra current situation report " shows: the teenager cervical vertebra of more than 80% is in sub-health state.
Research shows: the cervical spondylosis incidence probability of people who bends over one's desk working for a long time is 4 to 6 times of the non-work crowd that bows, and overall sickness rate reaches 15%.In " the 2008 international orthopaedics scientific seminar " recently terminated, north doctor three institute chief physician Sun Yu reminds the public, needs to have a short interval after work half an hour of bowing.Now along with the quickening of life step, operating pressure is large, and the people of a lot of working, in ignorant situation, just suffers from cervical spondylosis.Cervical spondylosis, also known as cervical spine syndrome, is the general name of osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion; It is a kind of illness changing into basis with degeneration pathology.Be mainly in labourer and middle-aged population, the age of the patient of cervical spondylosis becomes younger gradually.
Expert points out, cervical spondylosis early symptom mainly contains following 3 points:
1, cervical spondylosis there will be head, cervical region, shoulder etc. in early days and occurs symptoms such as aching, and neck has a stiff neck, and neck shoulder is ached and can be radiated to headrest portion and upper limb, have with dizziness, house rotate, severe one is with nausea and vomiting, be unable to leave the bed, minority can have dizzy, dampings off.The side surface part heating had, exception of sometimes perspiring.
2, Patients with Cervical Spondylopathy has shoulder back sense of heaviness in early days, and upper myasthenia of limbs, points numb, and limb skin is felt to go down, and holds thing unable, sometimes automaticly holds the symptoms such as thing lands.Other patient's weakness of the lower extremitiess, walking is unstable, and two foot numbnesses, as stepped on the sensation of Cotton Gossypii during walking.Dizziness, headache, blurred vision can be there is when cervical spondylosis involves sympathetic nerve, two are swollen, dry, two Zhang Bukai, tinnitus, ear are stifled, dysequilibrium, tachycardia, nervous, the tight Bouquet sense in breast portion, even there is flatulence in what have.
3, minority Patients with Cervical Spondylopathy is had to there will be stool, urine in early days out of control, sexual dysfunction, even the symptom such as quadriplegia.Also dysphagia is had, dysphonia etc.These performance and occurring degrees, disease time length, the body constitution of individual has certain relation.During most onset gently and be not valued by the people, majority can recover voluntarily, time light time heavy, only have when symptom continues to increase the weight of and can not reverse, just draw attention when affecting work and life.If disease obstinate, can menticide be caused, produce the symptoms such as insomnia, irritated, angry, anxiety, melancholy.Cervical spondylosis is sudden onset at certain time always, and onset is rapid, very painful, but does not have sign, before the typical case's discomfort caused by cervical spondylosis appears in formation cervical spondylosis, still has a lot of sign governed.If according to these signs, can make a change early and prevented, cervical spondylosis is eliminated among rudiment, compared with the treatment of cervical spondylosis, much easier.The traditional Chinese medical science is thought and is occurred that above-mentioned symptom is passages through which vital energy circulates impatency, and attack outside wind-cold damp pathogen, impairment caused by overstrain muscle of a specified duration, body constitution virtual loss, sclerotin is not hard, caused by energy stagnation and blood stasis.For treatment above-mentioned symptom, the traditional Chinese medical science often adopts promoting the circulation of QI to relieve pain, warming kidney for dispelling cold, promoting blood circulation to remove obstruction in the collateral, the method for dissipating blood stasis eliminating impediment.Compared with Western medicine, the early stage cervical spondylosis for the treatment of by Chinese herbs is safe and reliable, low cost, evident in efficacy.
Summary of the invention
The present invention, according to Traditional Chinese medical theory, through a large amount of screenings to drug component, restructuring, trial, is made by lot of experiments again.Therefore, the object of the present invention is to provide a kind of medicine of more safe and reliable auxiliary treatment cervical spondylosis.
The object of the present invention is achieved like this:
The medicine of a kind of auxiliary treatment cervical spondylosis of the present invention, is prepared from by the Chinese crude drug of following weight portion: Flos Carthami 3-12 part, Radix Angelicae Pubescentis 3-12 part, Radix Angelicae Sinensis 5-16 part, Radix Paeoniae Alba 5-16 part, Radix Glycyrrhizae 2-9 part, Semen Persicae 3-7 part, Radix Achyranthis Bidentatae 3-7 part, Myrrha 2-9 part, Ramulus Cinnamomi 1-7 part, Rhizoma Zingiberis Recens 2-8 part, Radix Saposhnikoviae 3-7 part, Herba Lycopodii 3-10 part, Herba Asari 0.5-2.5 part, Caulis Spatholobi 8-15 part.
Preferably, the medicine of above-mentioned auxiliary treatment cervical spondylosis, is prepared from by the Chinese crude drug of following weight portion: Flos Carthami 4-10 part, Radix Angelicae Pubescentis 4-9 part, Radix Angelicae Sinensis 6-12 part, Radix Paeoniae Alba 7-14 part, Radix Glycyrrhizae 2-5 part, Semen Persicae 4-7 part, Radix Achyranthis Bidentatae 3-6 part, Myrrha 2-6 part, Ramulus Cinnamomi 2-6 part, Rhizoma Zingiberis Recens 3-8 part, Radix Saposhnikoviae 3-6 part, Herba Lycopodii 4-10 part, Herba Asari 0.5-2 part, Caulis Spatholobi 9-13 part.
Further preferably, the medicine of above-mentioned auxiliary treatment cervical spondylosis, is prepared from by the Chinese crude drug of following weight portion: Flos Carthami 4-6 part, Radix Angelicae Pubescentis 4-7 part, Radix Angelicae Sinensis 6-10 part, Radix Paeoniae Alba 7-10 part, Radix Glycyrrhizae 3-5 part, Semen Persicae 4-6 part, Radix Achyranthis Bidentatae 4-6 part, Myrrha 4-6 part, Ramulus Cinnamomi 2-4 part, Rhizoma Zingiberis Recens 3-6 part, Radix Saposhnikoviae 3-5 part, Herba Lycopodii 4-7 part, Herba Asari 0.5-1.5 part, Caulis Spatholobi 9-10 part.
In a most preferred embodiment, the medicine of described auxiliary treatment cervical spondylosis, is prepared from by the Chinese crude drug of following weight portion: 5 parts, Flos Carthami, Radix Angelicae Pubescentis 6 parts, Radix Angelicae Sinensis 6 parts, the Radix Paeoniae Alba 8 parts, 4 parts, Radix Glycyrrhizae, 5 parts, Semen Persicae, Radix Achyranthis Bidentatae 5 parts, Myrrha 5 parts, Ramulus Cinnamomi 3 parts, 5 parts, Rhizoma Zingiberis Recens, Radix Saposhnikoviae 4 parts, Herba Lycopodii 5 parts, Herba Asari 1 part, Caulis Spatholobi 9 parts.
Further preferably, the medicine of described auxiliary treatment cervical spondylosis is oral formulations.
Again further preferably, the medicine of described auxiliary treatment cervical spondylosis is oral liquid, granule, tablet or capsule.
Found by clinical application research, the pharmaceutical composition be prepared from by above-mentioned Chinese crude drug obtains satisfied curative effect in auxiliary treatment Patients with Cervical Spondylopathy.Therefore, second object of the present invention is to provide a kind of new medical use, i.e. the application of said medicine in preparation auxiliary treatment cervical spondylosis Chinese medicine.
According to Chinese medicine Historical Data Data About, above-mentioned Chinese crude drug has following pharmacologically active and function cures mainly:
Flos Carthami, nature and flavor are pungent, temperature.Promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.Control amenorrhea ， mass in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, injury from falling down.Be selected from the dried floral of feverfew Flos Carthami Carthamus tinctorius L..
Radix Angelicae Pubescentis, nature and flavor are pungent, bitter, tepor.Expelling wind and dampness; Dispersing cold for relieving pain.For anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache.Be selected from the dry root of samphire Angelica pubescens Angelica pubescens Maxim. f. biserrata Shan et Yuan.
Radix Angelicae Sinensis, nature and flavor are sweet, pungent, warm.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.For blood deficiency, shallow complexion, dizzy cardiopalmus; Blood deficiency, or have the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea concurrently; The pain such as deficient cold type stomachache, angina pectoris, rheumatic arthralgia, traumatic injury card; Dryness of the intestine constipation; Chronic cough is panted.Be selected from the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.
The Radix Paeoniae Alba, nature and flavor are bitter, sour, are slightly cold.Suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.Be selected from the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..
Radix Glycyrrhizae, sweet in the mouth is flat.Cure mainly (effect): invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Be selected from the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..
Semen Persicae, nature and flavor bitter, sweet, flat.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Be selected from the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus davidiana (Carr.) Franch..
Radix Achyranthis Bidentatae, nature and flavor are bitter, sour, flat.Invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.Be selected from the dry root of amaranthaceous plant Radix Achyranthis Bidentatae Achyranthes bidentata Blume..
Myrrha, nature and flavor are bitter, flat.Eliminating stasis to stop pain, externally used detumescence granulation promoting.Swell and ache for traumatic injury congestion, ulcer sore pain, all pains of breast abdomen; External is controlled the open sore part and is not restrained for a long time.Be selected from the oleo-gum-resin that Burseraceae bdellium plant myrrh Commiphora myrrha Engl. [C. molmol Engl.] and the trunk skin zone that belongs to his kind of plant together ooze out.
Ramulus Cinnamomi, nature and flavor acrid, sweet, warm.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.Be selected from the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.
Rhizoma Zingiberis Recens, nature and flavor are pungent, tepor.Induce sweat cold expelling, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing.For anemofrigid cold, gastrofrigid vomiting, cold-phlegm is coughed.Be selected from the fresh rhizome of zingiber Zingiber officinale Rosc..
Radix Saposhnikoviae, nature and flavor acrid, sweet, warm.Inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.Be selected from the dry root of umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk..
Herba Lycopodii, property mildly bitter flavor, pungent, temperature.Expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.For joint aches, joint stuffiness.Be selected from the dry herb of lycopsid Lycopodium clavatum Lycopodium japonicum Thunb..
Herba Asari, nature and flavor are pungent, temperature.Expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.Be selected from aristolochiaceae plant Herba Asari Asarum heterotropoides Fr. Schmidt var.mandshuricum(Maxim.) the dry herb of Kitag., Seoul Herba Asari Asarum sieboldii Miq. var. seoulense Nakai or magnificent Herba Asari Asarum sieboldii Miq..
Caulis Spatholobi, nature and flavor are bitter, sweet, temperature.Enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Be selected from the dry rattan of leguminous plant spatholobus suberectus (Caulis Sargentodoxae, Radix seu Caulis Verntilaginis Leiocarpae, SANYE Caulis Spatholobi, nine layers of wind) Spatholobus suberectus Dunn.
Above-mentioned each Chinese crude drug is prepared into the preparation method of compound oral liquid of the present invention, comprise the steps: to take according to quantity and clean up and the Flos Carthami of drying, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Glycyrrhizae, Semen Persicae, Radix Achyranthis Bidentatae, Myrrha, Ramulus Cinnamomi, Rhizoma Zingiberis Recens, Radix Saposhnikoviae, Herba Lycopodii, Herba Asari, Caulis Spatholobi, merge, decoct with water twice, collecting decoction, when being evaporated to 70 DEG C, relative density is 1.15-1.20, adding ethanol makes the percent by volume of alcohol content reach 75-85%, stir, leave standstill, filter, during filtrate reduced in volume to 70 DEG C, relative density is 1.10-1.20 and reclaims ethanol to obtain concentrated solution, concentrated solution to be added water and auxiliaries becomes oral liquid.
Above-mentioned each traditional Chinese medicine powder also can be broken into powder by those skilled in the art, obtains granule, tablet or capsule according to routine techniques means.
Compared with prior art, tool of the present invention has the following advantages and progress significantly: (1) good effect.Found by a large amount of clinical practices, the medicine that the present invention relates to can not only treat the symptom such as pain, numbness, dizziness that cervical vertebra discomfort is brought, and persistent, and treating both the principal and secondary aspects of a disease, has no side effect, efficacy consolidation.Further, lot of experiments research display, most cervical vertebra disease patient takes medicine of the present invention and namely occurs obvious curative effects 1 course for the treatment of.(2) safety is high.Because medicine of the present invention is prepared from by adopting Chinese medicine material, toxicity is low, and patient medication is safer.
Detailed description of the invention
The present invention is further illustrated below by embodiment.Embodiments of the invention are only used for the present invention is described, instead of limitation of the present invention, under concept thereof of the present invention, all belong to the scope of protection of present invention to the simple modifications of preparation method of the present invention.
Embodiment 1 prepares the medicine oral liquid of auxiliary treatment cervical spondylosis
Crude drug prescription: 4 parts, Flos Carthami, Radix Angelicae Pubescentis 5 parts, Radix Angelicae Sinensis 6 parts, the Radix Paeoniae Alba 7 parts, 2 parts, Radix Glycyrrhizae, 4 parts, Semen Persicae, Radix Achyranthis Bidentatae 3 parts, Myrrha 2 parts, Ramulus Cinnamomi 2 parts, 3 parts, Rhizoma Zingiberis Recens, Radix Saposhnikoviae 3 parts, Herba Lycopodii 4 parts, Herba Asari 0.5 part, Caulis Spatholobi 8 parts.
Preparation method: the medical material taking above-mentioned recipe quantity merges, decoct with water twice, first time adds water as 10 times amount of medical material weight, decoct 2h, second time adds water as 8 times amount of medical material weight, decoct 1.5h, collecting decoction, 0.08MPa, relative density is 1.15 when being evaporated to 70 DEG C at 70 DEG C, adds 95% (v/v) ethanol and makes alcohol content reach 75% (v/v), stir, hold over night, filter, under 0.08MPa, 65 DEG C of conditions, concentrating under reduced pressure becomes filtrate is 1.15g/mL to relative density when 65 DEG C, adds water and sucrose is mixed with oral liquid.
Embodiment 2 prepares the medicine oral liquid of auxiliary treatment cervical spondylosis
Crude drug prescription: 6 parts, Flos Carthami, Radix Angelicae Pubescentis 4 parts, Radix Angelicae Sinensis 7 parts, the Radix Paeoniae Alba 9 parts, 3 parts, Radix Glycyrrhizae, 6 parts, Semen Persicae, Radix Achyranthis Bidentatae 4 parts, Myrrha 4 parts, Ramulus Cinnamomi 4 parts, 4 parts, Rhizoma Zingiberis Recens, Radix Saposhnikoviae 5 parts, Herba Lycopodii 6 parts, Herba Asari 1.5 parts, Caulis Spatholobi 10 parts.
Preparation method: the medical material taking above-mentioned recipe quantity merges, decoct with water twice, first time adds water as 10 times amount of medical material weight, decoct 2h, second time adds water as 8 times amount of medical material weight, decoct 1.5h, collecting decoction, 0.08MPa, relative density is 1.15 when being evaporated to 70 DEG C at 70 DEG C, adds 95% (v/v) ethanol and makes alcohol content reach 85% (v/v), stir, hold over night, filter, under 0.08MPa, 65 DEG C of conditions, concentrating under reduced pressure becomes filtrate is 1.15g/mL to relative density when 65 DEG C, adds water and sucrose is mixed with oral liquid.
Embodiment 3 prepares the medicine oral liquid of auxiliary treatment cervical spondylosis
Crude drug prescription: 12 parts, Flos Carthami, Radix Angelicae Pubescentis 12 parts, Radix Angelicae Sinensis 16 parts, the Radix Paeoniae Alba 16 parts, 9 parts, Radix Glycyrrhizae, 7 parts, Semen Persicae, Radix Achyranthis Bidentatae 7 parts, Myrrha 9 parts, Ramulus Cinnamomi 7 parts, 8 parts, Rhizoma Zingiberis Recens, Radix Saposhnikoviae 7 parts, Herba Lycopodii 10 parts, Herba Asari 2.5 parts, Caulis Spatholobi 15 parts.
Preparation method: the medical material taking above-mentioned recipe quantity merges, decoct with water twice, first time adds water as 10 times amount of medical material weight, decoct 2h, second time adds water as 8 times amount of medical material weight, decoct 1.5h, collecting decoction, 0.08MPa, relative density is 1.20 when being evaporated to 70 DEG C at 70 DEG C, adds 95% (v/v) ethanol and makes alcohol content reach 80% (v/v), stir, hold over night, filter, under 0.08MPa, 65 DEG C of conditions, concentrating under reduced pressure becomes filtrate is 1.15g/mL to relative density when 65 DEG C, adds water and sucrose is mixed with oral liquid.
Embodiment 4 medicine of the present invention is to the effectiveness study of early stage Patients with Cervical Spondylopathy
Chinese medicine oral liquid sample preparation: take 5 parts, Flos Carthami, Radix Angelicae Pubescentis 6 parts, Radix Angelicae Sinensis 6 parts, the Radix Paeoniae Alba 8 parts, 4 parts, Radix Glycyrrhizae, 5 parts, Semen Persicae, Radix Achyranthis Bidentatae 5 parts, Myrrha 5 parts, Ramulus Cinnamomi 3 parts, 5 parts, Rhizoma Zingiberis Recens, Radix Saposhnikoviae 4 parts, Herba Lycopodii 5 parts, Herba Asari 1 part, Caulis Spatholobi 9 parts, the medical material of above-mentioned recipe quantity is merged, decoct with water twice, first time adds water as 10 times amount of medical material weight, decoct 2h, second time adds water as 8 times amount of medical material weight, decoct 1.5h, collecting decoction, 0.08MPa, when being evaporated to 70 DEG C at 70 DEG C, relative density is 1.15, adding 95% (v/v) ethanol makes alcohol content reach 75% (v/v), stir, hold over night, filter, filtrate is at 0.08MPa, under 65 DEG C of conditions, concentrating under reduced pressure one-tenth is 1.15g/mL to relative density when 65 DEG C, .
According to " Chinese medical disease Standardization of diagnosis and curative effect ", the diagnosis basis of cervical spondylosis: 1. have chronic strain or trauma history.Or have cervical vertebra congenital malformation, cervical vertebra degeneration.2. be mainly in more than 40 years old middle age, bow for a long time worker or custom with see TV, picture recording person for a long time, be often chronic disease.3. neck, shoulder and back ache, headache and dizzy, neck board is hard, upper limb numbness.4. cervical region movable function is limited, pathological changes cervical spine, and in Ipsilateral scapula, often there is tenderness at upper angle, can touch strip scleroma, upper extremity strength can be had to weaken and amyotrophy, and brachial plexus distraction test is positive.Head test is positive.5. X-ray normotopia takes the photograph sheet display, uncovertebral joint hypertrophy, and mouth-open can have chisel-like prominent partially askew, and position, side is taken the photograph sheet display cervical curvature and straightened, and narrowing of intervertebral space, has hyperosteogeny or ligament calcification, and loxosis is taken the photograph the visible intervertebral foramina of sheet and diminished.CT and magnetic resonance examination are diagnosed meaningful to qualitative positioning.
Efficacy evaluation is as follows:
Cure: original various disease disappears, and muscular strength is normal, and neck, limb functional recover are normal, normal work and work can be participated in.
Take a turn for the better: original various symptom alleviates, and neck, shoulder and back ache alleviate, neck, limb function improve.
Do not heal: symptom is without improvement.
Using method: above-mentioned gained medicine juice is divided into two parts, respectively takes portion sooner or later.It within one week, is a course for the treatment of.
Through clinical practice for many years, add up the patient that 56 examples have early stage cervical spondylosis symptom, minimum 17 years old of age, maximum 58 years old, man 26 example, female 30 example.Cure 43 examples, take a turn for the better 12 examples, and do not heal 1 example.Medicine of the present invention is without any side effects, and without drug dependence, formula is simple, and taking convenience, cost is low, good effect, and effective percentage is high.
Found by a large amount of clinical practices, the medicine that the present invention relates to can not only treat the symptom such as pain, numbness, dizziness that cervical vertebra discomfort is brought, and persistent, and treating both the principal and secondary aspects of a disease, has no side effect, efficacy consolidation.Further, lot of experiments research display, the early stage Patients with Cervical Spondylopathy of the overwhelming majority is taken medicine of the present invention and is namely occurred obvious curative effects 1 course for the treatment of, stops the state of an illness to worsen further, continues to take cure rate higher.
Claims (7)
1. a medicine for auxiliary treatment cervical spondylosis, is characterized in that being prepared from by the Chinese crude drug of following weight portion: Flos Carthami 3-12 part, Radix Angelicae Pubescentis 3-12 part, Radix Angelicae Sinensis 5-16 part, Radix Paeoniae Alba 5-16 part, Radix Glycyrrhizae 2-9 part, Semen Persicae 3-7 part, Radix Achyranthis Bidentatae 3-7 part, Myrrha 2-9 part, Ramulus Cinnamomi 1-7 part, Rhizoma Zingiberis Recens 2-8 part, Radix Saposhnikoviae 3-7 part, Herba Lycopodii 3-10 part, Herba Asari 0.5-2.5 part, Caulis Spatholobi 8-15 part.
2. the medicine of auxiliary treatment cervical spondylosis as claimed in claim 1, is characterized in that being prepared from by the Chinese crude drug of following weight portion: Flos Carthami 4-10 part, Radix Angelicae Pubescentis 4-9 part, Radix Angelicae Sinensis 6-12 part, Radix Paeoniae Alba 7-14 part, Radix Glycyrrhizae 2-5 part, Semen Persicae 4-7 part, Radix Achyranthis Bidentatae 3-6 part, Myrrha 2-6 part, Ramulus Cinnamomi 2-6 part, Rhizoma Zingiberis Recens 3-8 part, Radix Saposhnikoviae 3-6 part, Herba Lycopodii 4-10 part, Herba Asari 0.5-2 part, Caulis Spatholobi 9-13 part.
3. the medicine of auxiliary treatment cervical spondylosis as claimed in claim 2, is characterized in that being prepared from by the Chinese crude drug of following weight portion: Flos Carthami 4-6 part, Radix Angelicae Pubescentis 4-7 part, Radix Angelicae Sinensis 6-10 part, Radix Paeoniae Alba 7-10 part, Radix Glycyrrhizae 3-5 part, Semen Persicae 4-6 part, Radix Achyranthis Bidentatae 4-6 part, Myrrha 4-6 part, Ramulus Cinnamomi 2-4 part, Rhizoma Zingiberis Recens 3-6 part, Radix Saposhnikoviae 3-5 part, Herba Lycopodii 4-7 part, Herba Asari 0.5-1.5 part, Caulis Spatholobi 9-10 part.
4. the medicine of auxiliary treatment cervical spondylosis as claimed in claim 3, is characterized in that being prepared from by the Chinese crude drug of following weight portion: 5 parts, Flos Carthami, Radix Angelicae Pubescentis 6 parts, Radix Angelicae Sinensis 6 parts, the Radix Paeoniae Alba 8 parts, 4 parts, Radix Glycyrrhizae, 5 parts, Semen Persicae, Radix Achyranthis Bidentatae 5 parts, Myrrha 5 parts, Ramulus Cinnamomi 3 parts, 5 parts, Rhizoma Zingiberis Recens, Radix Saposhnikoviae 4 parts, Herba Lycopodii 5 parts, Herba Asari 1 part, Caulis Spatholobi 9 parts.
5. the medicine of the auxiliary treatment cervical spondylosis as described in as arbitrary in claim 1-4, is characterized in that: the medicine of described auxiliary treatment cervical spondylosis is oral formulations.
6. the medicine of auxiliary treatment cervical spondylosis as claimed in claim 5, is characterized in that: described oral formulations is oral liquid, granule, tablet or capsule.
7. the medicine of auxiliary treatment cervical spondylosis as claimed in claim 6, it is characterized in that, the preparation method of described oral liquid comprises the following steps: take according to quantity and clean up and the Flos Carthami of drying, Radix Angelicae Pubescentis, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Glycyrrhizae, Semen Persicae, Radix Achyranthis Bidentatae, Myrrha, Ramulus Cinnamomi, Rhizoma Zingiberis Recens, Radix Saposhnikoviae, Herba Lycopodii, Herba Asari, Caulis Spatholobi, merge, decoct with water twice, collecting decoction, when being evaporated to 70 DEG C, relative density is 1.15-1.20, adding ethanol makes the percent by volume of alcohol content reach 75-85%, stir, leave standstill, filter, during filtrate reduced in volume to 70 DEG C, relative density is 1.10-1.20 and reclaims ethanol to obtain concentrated solution, concentrated solution to be added water and auxiliaries becomes oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410595570.XA CN104306942A (en) | 2014-10-30 | 2014-10-30 | Medicine for auxiliary treatment on cervical spondylosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410595570.XA CN104306942A (en) | 2014-10-30 | 2014-10-30 | Medicine for auxiliary treatment on cervical spondylosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104306942A true CN104306942A (en) | 2015-01-28 |
Family
ID=52362351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410595570.XA Pending CN104306942A (en) | 2014-10-30 | 2014-10-30 | Medicine for auxiliary treatment on cervical spondylosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104306942A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112675226A (en) * | 2021-02-05 | 2021-04-20 | 复旦大学附属金山医院(上海市金山区核化伤害应急救治中心、上海市金山区眼病防治所) | Fumigation-washing traditional Chinese medicine composition for treating pain and application thereof |
| CN116870128A (en) * | 2023-08-03 | 2023-10-13 | 北京圣骨堂健康管理发展有限公司 | Combined medicine for treating bone and muscle pain and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101380371A (en) * | 2008-10-16 | 2009-03-11 | 高子泉 | Manufacture method of prepared Chinese medicament for treating cervical vertebra disease |
-
2014
- 2014-10-30 CN CN201410595570.XA patent/CN104306942A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101380371A (en) * | 2008-10-16 | 2009-03-11 | 高子泉 | Manufacture method of prepared Chinese medicament for treating cervical vertebra disease |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112675226A (en) * | 2021-02-05 | 2021-04-20 | 复旦大学附属金山医院(上海市金山区核化伤害应急救治中心、上海市金山区眼病防治所) | Fumigation-washing traditional Chinese medicine composition for treating pain and application thereof |
| CN116870128A (en) * | 2023-08-03 | 2023-10-13 | 北京圣骨堂健康管理发展有限公司 | Combined medicine for treating bone and muscle pain and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103550517B (en) | A kind of medicine of Hepatoma therapy | |
| CN101721664A (en) | Traditional Chinese medicine for treating apoplectic hemiplegia and general paralysis | |
| CN101015651A (en) | Medicine for treating protrusion of lumbar intervertebral disc | |
| CN101926961B (en) | Oral Chinese medicinal composition for treating pelvic inflammatory disease | |
| CN101829217B (en) | Traditional Chinese medicine for treating chronic colitis | |
| CN107693767A (en) | A kind of external medicine composition, its preparation method and application for preventing and treating diabetes | |
| CN101773585B (en) | Chinese medicine for treating facial paralysis | |
| CN104758852A (en) | Traditional Chinese medicine composition for treating hypertension | |
| CN104623561A (en) | Traditional Chinese medicine for treating hyperplasia of mammary glands | |
| CN100525827C (en) | Chinese-medicinal composition for treating difficult menstruation | |
| CN103393825B (en) | Traditional Chinese medicine for treating catatonic headache and preparation method thereof | |
| CN104306942A (en) | Medicine for auxiliary treatment on cervical spondylosis | |
| CN105106802A (en) | Traditional Chinese medicine composition for treating peripheral facial paralysis | |
| CN105168881A (en) | Traditional Chinese medicinal composition for treating stages I and II of chronic renal failure | |
| CN100998656A (en) | Medicated wine for tonifying bone and removing obstruction in channels | |
| CN104825561A (en) | Traditional Chinese medicine for treating arthritis | |
| CN104189668A (en) | Traditional Chinese medicine composition for treating coronary heart disease | |
| CN105663913A (en) | Traditional Chinese medicine composition for treating lumbar disc herniation | |
| CN103494939A (en) | Traditional Chinese medicine for treating senile habitual constipation | |
| CN105079549A (en) | Traditional Chinese medicine for treating lupus nephritis | |
| CN105663408A (en) | Decoction medicine for treating abnormal menstruation and insufficient menstrual blood volume as well as preparation method thereof | |
| CN103356959B (en) | Pharmaceutical composition for treating hyperplasia of mammary glands | |
| CN103393868A (en) | Electuary for cervical vertebral rehabilitation | |
| CN103845547A (en) | Traditional Chinese medicine decoction for treating mumps | |
| CN105748816A (en) | Medicine for treating fallopian tube obstruction |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Ji Rifeng Inventor after: Wu Shaoqin Inventor before: Cui Yinfang |
|
| CB03 | Change of inventor or designer information | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150128 |
|
| RJ01 | Rejection of invention patent application after publication |