CN105194592A - Arthralgia clearing traditional Chinese medicine composition and preparation method thereof - Google Patents
Arthralgia clearing traditional Chinese medicine composition and preparation method thereof Download PDFInfo
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Abstract
The invention relates to an arthralgia clearing traditional Chinese medicine composition used for treating arthralgia in a direct-current iontophoresis mode. The arthralgia clearing traditional Chinese medicine composition is prepared from angelica sinensis, achyranthes bidentata, red peony roots, angelica pubescens, caulis sargentodoxae, ginger, olibanum, myrrh, radix aconiti preparata, monkshood, pinellia ternate, eucommia ulmoides, fructus psoraleae and cistanche salsa. The invention further provides a preparation method of the arthralgia clearing traditional Chinese medicine composition and a direct-current iontophoresis system.
Description
Technical field
The present invention relates to a kind of clear numbness Chinese medicine composition and preparation method thereof, particularly relate to a kind of Chinese medicine composition for iontophoresis arthromyodynia and preparation method thereof.
Background technology
" arthromyodynia " alleged by the traditional Chinese medical science refer to human body machine table and meridians because of sense wind, cold, wet, heat etc. cause with limbs joint and muscular soreness, numbness, weigh, joint stuffiness, even the scorching hot grade of arthroncus is a class disease of primary symptom.There is feature that is gradual or repeated relapsing clinically.Main pathogenesis be QI and blood numbness resistance obstructed, muscle arteries and veins joint lose in moisten support caused by.Rheumatism, rheumatic arthritis, rheumatoid arthritis, osteoarthritis, gout, Raynand's disease, ankylosing spondylitis, sciatica, osteoarthritis, hyperosteogeny etc. the degenerative disease of modern medicine all belongs to " arthromyodynia " category.
Western medical treatment arthromyodynia is to control acute attack, Long-term taking medicine, and conventional oral drugs have certain analgesic effect, but stimulates comparatively large to the intestines and stomach, easily recurs after drug withdrawal; Glucocorticoid medicine can only short-period used, and long-term taking can reduce joint immunity, increases the weight of the state of an illness on the contrary.
By contrast, the traditional Chinese medical science have accumulated comparatively rich experience in treatment arthromyodynia, is becoming clinical research focus at present.Wherein, by ion-introduction therapy, external medicine composition local penetration is entered the mode at aura position, not only improve the drug level of local targetedly, rapid-action, good effect, and absorb without the intestines and stomach due to medicine, so substantially have no side effect, total dosage is also only ten parts of oral drugs.
But there is the problem of following several respects in the pharmaceutical admixtures of current existing iontophoresis arthromyodynia:
One is that pharmaceutical formulation falls behind.Although be all belong to the traditional Chinese medical science " arthromyodynia " therapeutic domain, many pharmaceutical formulations can only be effective for a handful of position, and will treat different parts clinically needs to prepare different pharmaceutical compositions, all causes trouble to patient and doctor.
Two be pharmaceutical composition preparation means fall behind.Conventional ion imports the preparation of pharmaceutical composition generally based on decocting method, and this method is strict to time requirement, but due to pharmaceutical composition composition complexity, cannot ensure the decocting time that often kind of medicine can reach best.In addition, this mode is comparatively large to the component damage of Chinese medicine own, and the herb liquid active constituent content of extraction is lower, affects therapeutic effect, and is difficult to long-time preservation under normal conditions.
Three be iontophoresis concrete operation method fall behind.During Traditional DC current iontophoresis, anode medicated cushion and negative electrode medicated cushion use medicine different, two kinds of medicinal liquids must be prepared simultaneously, the medicine ion of positively charged penetrates from anode medicated cushion, electronegative medicine ion penetrates from negative electrode medicated cushion, during operation, anode medicated cushion and negative electrode medicated cushion are placed in specific part separated by a distance, as shown in FIG. 1A and 1B, the placement schematic diagram of medicated cushion when it is respectively traditional lumbar treatment and cervical vertebra treatment.This operational approach requires that electric current reaches some strength (being generally more than 8mA) to obtain good therapeutic effect, but heavy current is very large to skin irritation, and specific operation process is more complicated, larger to skin irritation, most patients is difficult to accept for a long time treatment continuously, have impact on curative effect.
In addition, although it is also proposed the herbal ion penetration compositions that some treat some type arthromyodynia at present, but totally it seems, still there is various undesirable problem, technical staff, for this reason still in continuous effort, ites is desirable to develop a kind of, clear numbness Chinese medicine composition of preparing the improvement of the advantages such as easy, simple, convenient storage high with efficiency.
Summary of the invention
For solving the problem, the present invention proposes a kind of clear numbness Chinese medicine composition, can in order to treat arthromyodynia by the electro-ionic mode of direct current.
Effective ingredient according to clear numbness Chinese medicine composition of the present invention can be made up of following crude drug: Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, Radix Paeoniae Rubra, Radix Angelicae Pubescentis, Caulis Sargentodoxae, Rhizoma Zingiberis Recens, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Aconiti Lateralis Preparata, the Rhizoma Pinelliae, the Cortex Eucommiae, Fructus Psoraleae and Herba Cistanches.
Preferably, the effective ingredient of described clear numbness Chinese medicine composition can be made up of the crude drug of following weight portion: Radix Angelicae Sinensis 20 ?60, Radix Achyranthis Bidentatae 20 ?60, Radix Paeoniae Rubra 20 ?60, Radix Angelicae Pubescentis 20 ?60, Caulis Sargentodoxae 10 ?40, Rhizoma Zingiberis Recens 40 ?80, Olibanum 15 ?30, Myrrha 15 ?30, Radix Aconiti Preparata 8 ?20, Radix Aconiti Lateralis Preparata 15 ?30, the Rhizoma Pinelliae 30 ?80, the Cortex Eucommiae 25 ?60, Fructus Psoraleae 25 ?60 and Herba Cistanches 25 ?60.
Above-mentioned Chinese medicine composition object space solution is as follows: Radix Angelicae Sinensis sweet in the mouth, pungent, warm in nature, and return liver, the heart, spleen channel, function is enriched blood and invigorated blood circulation, and menstruction regulating and pain relieving cures mainly blood deficiency, stasis, all pains of cold in blood, traumatic injury, the diseases such as rheumatic arthralgia; The acid of Radix Achyranthis Bidentatae bitter but sweet flavor, property is put down.Return liver, kidney channel, function promoting blood circulation to restore menstrual flow, invigorating the liver and kidney, bone and muscle strengthening, cure mainly lumbago due to renal deficiency and lingering arthralgia soreness of waist and knee joint is weak; Radix Paeoniae Rubra bitter in the mouth, cold nature, returns Liver Channel, function clearing away heat and cooling blood, and eliminating stasis to stop pain, cures mainly traumatic injury; Radix Angelicae Pubescentis acrid in the mouth, bitter, warm in nature, return liver, kidney, urinary bladder channel, the timid wind dehumidifying of function, induce sweat cold expelling, cures mainly anemofrigid-damp arthralgia, the heavy pain of waist knee joint acid; Caulis Sargentodoxae bitter in the mouth, property is put down, and return large intestine channel, function heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, cures mainly traumatic injury, rheumatic arthralgia; Rhizoma Zingiberis Recens acrid in the mouth, warm in nature, return lung, spleen, stomach warp.A surname is loose for function pungent temperature, and timid wind, dissipating cold, cures mainly coldness and pain in the epigastrium, separates the poison of all medicines; Olibanum acrid in the mouth is bitter, warm in nature, returns liver, the heart, spleen channel, the pain relieving of function blood-activating and qi-promoting, cures mainly congestion and block all pain diseases; Myrrha bitter in the mouth is pungent, and property is put down, GUIXIN, liver, spleen channel, and function promoting blood circulation and stopping pain, cures mainly all pains of the stagnant trusted subordinate of all stasis of bloods, rheumatic arthralgia; Radix Aconiti Preparata acrid in the mouth is bitter, hot in nature, poisonous, GUIXIN, liver, kidney, spleen channel, the timid wind dehumidifying of function, and antalgic, cures mainly anemofrigid-damp arthralgia, severe and migratory arthralgia pain; Radix Aconiti Lateralis Preparata acrid in the mouth, sweet, hot in nature, poisonous, GUIXIN, kidney, spleen channel, it is supporing yang that function mends fire, and dispersing cold for relieving pain, cures mainly arthralgia due to cold disease etc.; Rhizoma Pinelliae acrid in the mouth, warm in nature, poisonous, return lung, spleen, stomach warp, function drying dampness to eliminate phlegm, dissolving lump and resolving mass, cure mainly damp-phlegm cold-phlegm, gall subcutaneous nodule; Cortex Eucommiae sweet in the mouth, warm in nature, return liver, kidney channel, function liver and kidney tonifying, strengthening the tendons and bones, cures mainly soreness of waist and knee joint, and muscles and bones is withered soft; Fructus Psoraleae acrid in the mouth, bitter, warm in nature, return kidney, spleen channel, function kidney invigorating and YANG supporting, cures mainly chills and pain of the waist and kness; Herba Cistanches sweet in the mouth, salty, warm in nature, return kidney, large intestine channel, function the kidney invigorating and essence nourishing, cures mainly chills and pain of the waist and kness, and muscles and bones is unable.
Present invention also offers the preparation method of above-mentioned clear numbness Chinese medicine composition, described method can comprise the following steps: (1) takes each crude drug mixing in described clear numbness Chinese medicine composition, with pure water 1000 ?3000 milliliters soak 8 ?18 hours (preferably 12 hours), add in soak again 55 ?65 degree of Chinese liquor 1000 ?3000 milliliters soak 8 ?18 hours (preferably 12 hours), then immersion gained medicinal liquid is poured out and deposits; (2) again add in the crude drug after step (1) is soaked pure water soak 8 ?18 hours (preferably 12 hours), then add 55 ?65 degree of Chinese liquor 1000 ?3000 milliliters soak 8 ?18 hours (preferably 12 hours); (3) step (1) and (2) gained medicinal liquid are merged, continue to soak crude drug 24 ?within 120 hours, pour out after (preferably 72 hours), filter for subsequent use.Wherein, consider effect and time cost, the soak time of step (1) and (2) was at 12 hours, and the time of step (3) was best at 72 hours.
The preparation method of clear numbness Chinese medicine composition of the present invention is that inventor sums up and draws in the practice of three more than ten years, according to the feature of herbal ion penetration medicinal liquid, utilize the principle of " the water extraction alcohol sedimentation method ", adopt " pure water " and the optimum solvent of " Chinese liquor " to combine the effective ingredient extracted in the middle of crude drug.Compared to traditional " decocting method ", the Chinese medicine composition iontophoresis liquid adopting " the water extraction alcohol sedimentation method " of the present invention to prepare has the following advantages: one, effective ingredient purity is high, medicinal liquid remains the effective ingredient such as alkaloid salts, glycoside, aminoacid, acylate, and eliminates the impurity such as protein, phlegmatic temperament, oils and fats, natural gum; Two, remain the effective ingredient in Chinese medicine more ideally, particularly can not destroy the biological active component of tool thermal sensitivity in Chinese medicine; Three, contain alcoholic content in medicinal liquid, can play bactericidal action, be easy to storage, facts have proved, Chinese medicine composition prepared by this method is stored at normal temperatures and is all undergone no deterioration for 18 months.
Preferably, above-mentioned clear numbness Chinese medicine composition can be the form of iontophoresis liquid, and to facilitate direct use, but the present invention is not limited to this.It will be understood by those skilled in the art that and can also utilize the general mode in this area that above-mentioned clear numbness Chinese medicine composition is made solid form, such as particle form further, to facilitate storage and transport, dissolve again during use.
During use, by full for the medicinal liquid of above-mentioned clear numbness Chinese medicine composition dipping medicated cushion, this medicated cushion is positioned on lesions position, anode is upper, negative electrode under, unidirectional current herbal ion penetration instrument can be used to import, make medicine ion transdermal go directly focus to play curative effect.
Therefore, present invention also offers a kind of unidirectional current iontophoresis system of clear numbness Chinese medicine composition, described system can comprise: with the medicated cushion of above-mentioned clear numbness Chinese medicine composition dipping, with unidirectional current herbal ion penetration instrument, wherein said medicated cushion is for being divided into upper and lower twoth district, upper district is in order to insert the anode of described unidirectional current herbal ion penetration instrument, inferior segment is in order to insert the negative electrode of described unidirectional current herbal ion penetration instrument, between described upper district and described inferior segment, there is physics to cut off, to make not contact between the anode of described unidirectional current herbal ion penetration instrument and negative electrode.
As the preferred embodiment of the present invention, for example, see shown in Fig. 2, medicated cushion can be designed growth 15cm, wide 13cm, cut off together by sewer at the central part of length, thus form twoth district up and down (in Fig. 2, left side is upper district, and right side is inferior segment) when using.During use, (be respectively the placement schematic diagram of medicated cushion of the present invention when lumbar treatment and cervical vertebra treatment) as shown in Figure 3 A and Figure 3 B, chloride plate is inserted in upper district pocket, negative electrode stereotype inserts in inferior segment pocket, the two poles of the earth do not come in contact, by medicated cushion after full for leaching medicinal liquid according to anode upper, negative electrode under mode be put in body foci position, connect unidirectional current herbal ion penetration instrument, regulate current intensity 2.5 ?the scope of 3.5mA, can start to treat and obtain good effect.General unidirectional current herbal ion penetration instrument can be buied on the market, as Shantou City, Guangdong Province medical equipment Co., Ltd., Factory produce DL ?ZII galvanofaradism apparatus.
Compared to traditional direct current Chinese Medicine Electrical iontophoresis system, different pharmaceutical will be used respectively due to anode medicated cushion and negative electrode medicated cushion and be placed on the different parts of health respectively, therefore anode medicated cushion and negative electrode medicated cushion also need separately to make.During use, such as, during waist treatment, generally anode medicated cushion is placed on waist Ashi point, negative electrode medicated cushion is placed on gastrocnemius; During cervical region treatment, generally anode medicated cushion is placed on cervical region Ashi point, negative electrode medicated cushion is placed on scapular region.Because anode medicated cushion and negative electrode medicated cushion putting position are separated by distant, utilize human-body conduction again, the intensity of electric current needs to be arranged on the therapeutic effect that more than 8mA just can reach usually, but, current intensity larger like this causes skin allergy and uncomfortable sometimes, even cause patient to be difficult to stand long-continued treatment, have a strong impact on curative effect.Utilize unidirectional current iontophoresis system of the present invention, can solve the problem well.
To sum up, clear numbness Chinese medicine composition of the present invention and preparation and application thereof are that inventor gropes for a long time to sum up in the clinical practice of nearly 30 years, and relative to existing technology, tool of the present invention has the following advantages:
A. the selected Chinese medicine formula of clear numbness Chinese medicine composition of the present invention, go numerously to deposit letter, the medicine that retention is best reasonable compatibility, make folk prescription just can corresponding all kinds of arthromyodynia, by clinical practice, patient can not only control the state of an illness very soon, and long-term effect is excellent, relapse rate is extremely low, and therapeutic effect is ideal;
B. the preparation method of described clear numbness Chinese medicine composition is original creation, and the medicinal liquid active constituent content of extraction is high, preserve and undergo no deterioration for 18 months, be convenient to transport, deposit, and concrete operations is easy to learn under normal condition, is convenient to promote;
When c. adopting the unidirectional current iontophoresis systematic treating of clear numbness Chinese medicine composition of the present invention, anode and cathode medication is identical and be separated by very near, is beneficial to the importing of effective ingredient, and stimulate little to patient skin, process health, low cost, make patient be easy to accept long-time continuous treatment, improve curative effect.
Other features and advantages of the present invention will be listed in the following description, or those skilled in the art will obviously realize some other feature and advantage after reading this specification or to after the present invention's practice.
Accompanying drawing explanation
Figure 1A and Figure 1B is unidirectional current herbal ion penetration medicated cushion and the modes of emplacement schematic diagram thereof of prior art;
Fig. 2 is unidirectional current herbal ion penetration medicated cushion floor map of the present invention;
Fig. 3 A and Fig. 3 B is the modes of emplacement schematic diagram of unidirectional current herbal ion penetration medicated cushion of the present invention.
Detailed description of the invention
In order to make object of the present invention, technical scheme and advantage clearly, below by way of specific embodiment, the present invention is further detailed.Should be appreciated that specific embodiment described herein only in order to explain the present invention, the protection domain be not intended to limit the present invention.
embodiment 1:
Take Radix Angelicae Sinensis 40g, Radix Achyranthis Bidentatae 40g, Radix Paeoniae Rubra 40g, Radix Angelicae Pubescentis 40g, Caulis Sargentodoxae 20g, Rhizoma Zingiberis Recens 60g, Olibanum 20g, Myrrha 20g, Radix Aconiti Preparata 10g, Radix Aconiti Lateralis Preparata 20g, Rhizoma Pinelliae 60g, Cortex Eucommiae 40g, Fructus Psoraleae 40g, Herba Cistanches 40g, mixing.Soak 12 hours with 2000 milliliters of pure water, then add 2000 milliliters of 55 degree of soaking in Chinese liquor 12 hours, then immersion gained medicinal liquid is poured out and deposit; Again add 2000 milliliters of pure water in crude drug after steeping and soak 12 hours, then add 2000 milliliters of 55 degree of soaking in Chinese liquor 12 hours; Soak gained medicinal liquid by twice to merge, continue to soak crude drug and pour out after 72 hours, filter for subsequent use.
embodiment 2
Take Radix Angelicae Sinensis 50g, Radix Achyranthis Bidentatae 50g, Radix Paeoniae Rubra 50g, Radix Angelicae Pubescentis 50g, Caulis Sargentodoxae 25g, Rhizoma Zingiberis Recens 70g, Olibanum 25g, Myrrha 25g, Radix Aconiti Preparata 15g, Radix Aconiti Lateralis Preparata 25g, Rhizoma Pinelliae 70g, Cortex Eucommiae 50g, Fructus Psoraleae 50g, Herba Cistanches 50g, mixing.All the other method for makings are with embodiment 1.
embodiment 3
Take Radix Angelicae Sinensis 40g, Radix Achyranthis Bidentatae 50g, Radix Paeoniae Rubra 60g, Radix Angelicae Pubescentis 60g, Caulis Sargentodoxae 20g, Rhizoma Zingiberis Recens 60g, Olibanum 25g, Myrrha 25g, Radix Aconiti Preparata 15g, Radix Aconiti Lateralis Preparata 25g, Rhizoma Pinelliae 60g, Cortex Eucommiae 50g, Fructus Psoraleae 50g, Herba Cistanches 50g, mixing.All the other method for makings are with embodiment 1.
embodiment 4
Take Radix Angelicae Sinensis 60g, Radix Achyranthis Bidentatae 60g, Radix Paeoniae Rubra 60g, Radix Angelicae Pubescentis 60g, Caulis Sargentodoxae 30g, Rhizoma Zingiberis Recens 80g, Olibanum 30g, Myrrha 30g, Radix Aconiti Preparata 20g, Radix Aconiti Lateralis Preparata 30g, Rhizoma Pinelliae 80g, Cortex Eucommiae 60g, Fructus Psoraleae 60g, Herba Cistanches 60g, mixing.All the other method for makings are with embodiment 1.
clinical trial example
Clinical statistics 320 routine arthromyodynia patients use clear numbness Chinese medicine composition of the present invention to carry out the situation of iontophoresis.Patient age is between 16 years old to 78 years old, and wherein male 150 people, women 170.Wherein clinical diagnosis suffers from prolapse of lumbar intervertebral disc 80 people, cervical spondylosis 80 people, degenerative knee 80 people, femur head necrosis 40 people, rheumatoid 30 people, does not have arthromyodynia patient 10 people of diagnosis final conclusion.
Get respectively above-described embodiment 1 ?the medicinal liquids of 4 preparations, abundant immersion medicated cushion, is put in sore spot, adopt Shantou City, Guangdong Province medical equipment Co., Ltd., Factory produce DL ?ZII galvanofaradism apparatus, carry out iontophoresis, regulate current intensity 2.5 ?between 3.5mA, each treatment 30 minutes, treats 1 every day, it within 10 days, is a course for the treatment of, have a rest two days between each course for the treatment of, observe patient's recovery situation after 12 courses for the treatment of, curative effect adds up as shown in table 1 below:
Table 1
Its standard of curative effect evaluation is as follows:
Cure: the classical symptom such as pain, numbness disappears completely or substantially disappears, without any discomfort sense;
Effective: the classical symptom such as pain, numbness obviously improves, accidental discomfort, but on life substantially without impact;
Effective: the classical symptom such as pain, numbness is necessarily improved, but still time have existence;
Invalid: symptom is not improved.
From table 1, it is quite high that clear numbness Chinese medicine composition of the present invention carries out iontophoresis method cure rate.
clinical model case
Ma, female, when treating 65 years old, suffer from prolapse of lumbar intervertebral disc, ct shows L4 ?L5 and charges into canalis spinalis 7 millimeters left afterwards, and left lower limb is numb, amyotrophy, adopt the clear numbness Chinese medicine composition of embodiment 2 to treat, after three courses for the treatment of (30 days), left lower limb feeling of numbness disappears substantially, after the systematic treating of 12 courses for the treatment of (120 days), left leg muscle recovers normal, clinical symptom disappearance, follows up a case by regular visits to 7 years without recurrence.
Cai so-and-so, man, when treating 38 years old, x mating plate display cervical vertebra curve is counter to bend, c3 ?c6 hyperosteogeny obvious, readme symptom both hands are numb, the dizzy vomiting of head, insomnia.Adopt the clear numbness Chinese medicine composition of embodiment 1 to treat, after three courses for the treatment of (30 days), both hands feeling of numbness disappears substantially, the dizzy vomiting number of times of head reduces, insomnia improves, and after the systematic treating of 12 courses for the treatment of (120 days), clinical symptoms disappears completely.Follow up a case by regular visits to 5 years without recurrence.
Lee, female, when treating 58 years old, left knee joint hydrops edema, the swelling slightly of right knee joint pain, adopts the clear numbness Chinese medicine composition of embodiment 4 to treat, and course for the treatment of (10 days) afterwards two knee joint swelling is obviously disappeared, three course for the treatment of (30 days) rear left knee joint hydrops edema disappear completely, right knee joint pain and swelling transference cure.Follow up a case by regular visits to 5 years rear left knee joints and have pain, treat the rehabilitation afterwards of a course for the treatment of (10 days).
The foregoing is only the preferred embodiment of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.
Claims (7)
1. a clear numbness Chinese medicine composition, is characterized in that, the effective ingredient of described clear numbness Chinese medicine composition is made up of following crude drug: Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, Radix Paeoniae Rubra, Radix Angelicae Pubescentis, Caulis Sargentodoxae, Rhizoma Zingiberis Recens, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Aconiti Lateralis Preparata, the Rhizoma Pinelliae, the Cortex Eucommiae, Fructus Psoraleae and Herba Cistanches.
2. clear numbness Chinese medicine composition according to claim 1, the effective ingredient of wherein said clear numbness Chinese medicine composition is made up of the crude drug of following weight portion: Radix Angelicae Sinensis 20-60, Radix Achyranthis Bidentatae 20-60, Radix Paeoniae Rubra 20-60, Radix Angelicae Pubescentis 20-60, Caulis Sargentodoxae 10-40, Rhizoma Zingiberis Recens 40-80, Olibanum 15-30, Myrrha 15-30, Radix Aconiti Preparata 8-20, Radix Aconiti Lateralis Preparata 15-30, Rhizoma Pinelliae 30-80, Cortex Eucommiae 25-60, Fructus Psoraleae 25-60 and Herba Cistanches 25-60.
3. clear numbness Chinese medicine composition according to claim 1 and 2, wherein said clear numbness Chinese medicine composition is clear numbness herbal ion penetration liquid.
4. the preparation method of clear numbness Chinese medicine composition according to any one of claim 1 to 3, it is characterized in that, said method comprising the steps of: (1) takes each crude drug mixing in described clear numbness Chinese medicine composition, 8-18 hour is soaked with pure water 1000-3000 milliliter, in soak, add 55-65 degree Chinese liquor 1000-3000 milliliter again soak 8-18 hour, then immersion gained medicinal liquid is poured out and deposit; (2) again add pure water in the crude drug after step (1) is soaked and soak 8-18 hour, then add 55-65 degree Chinese liquor 1000-3000 milliliter immersion 8-18 hour; (3) step (1) and (2) gained medicinal liquid are merged, continue to soak crude drug and pour out after 24-120 hour, filter for subsequent use.
5. the preparation method of clear numbness Chinese medicine composition according to claim 4, the soak time wherein in step (1) and step (2) is 12 hours.
6. the preparation method of the clear numbness Chinese medicine composition according to claim 4 or 5, the soak time wherein in step (3) is 72 hours.
7. the unidirectional current iontophoresis system of a clear numbness Chinese medicine composition, it is characterized in that, described system comprises: medicated cushion and unidirectional current herbal ion penetration instrument, wherein said medicated cushion is for being divided into upper and lower twoth district, upper district is in order to insert the anode of described unidirectional current herbal ion penetration instrument, inferior segment, in order to insert the negative electrode of described unidirectional current herbal ion penetration instrument, has physics between described upper district and described inferior segment and cuts off, to make not contact between the anode of described unidirectional current herbal ion penetration instrument and negative electrode.
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| CN201410281187.7A CN105194592B (en) | 2014-06-20 | 2014-06-20 | Clear numbness Chinese medicine composition and preparation method thereof |
| HK16102834.8A HK1214770A1 (en) | 2014-06-20 | 2016-03-11 | Chinese medicinal composition for treating arthromyodynia and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1090195A (en) * | 1993-11-17 | 1994-08-03 | 中国航空工业总公司第六○五研究所 | Medicine for curing comedo |
| CN201064622Y (en) * | 2007-04-29 | 2008-05-28 | 西藏宇妥藏药研究有限公司 | Ion leading-in medicine label convenient for storing and carrying |
| CN102600327A (en) * | 2012-03-06 | 2012-07-25 | 爨新德 | Ostealgia treating capsule |
| CN103372183A (en) * | 2012-04-16 | 2013-10-30 | 冯娜 | Pharmaceutical composition for treating cervical vertebra and lumbar vertebra diseases |
-
2014
- 2014-06-20 CN CN201410281187.7A patent/CN105194592B/en active Active
-
2016
- 2016-03-11 HK HK16102834.8A patent/HK1214770A1/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1090195A (en) * | 1993-11-17 | 1994-08-03 | 中国航空工业总公司第六○五研究所 | Medicine for curing comedo |
| CN201064622Y (en) * | 2007-04-29 | 2008-05-28 | 西藏宇妥藏药研究有限公司 | Ion leading-in medicine label convenient for storing and carrying |
| CN102600327A (en) * | 2012-03-06 | 2012-07-25 | 爨新德 | Ostealgia treating capsule |
| CN103372183A (en) * | 2012-04-16 | 2013-10-30 | 冯娜 | Pharmaceutical composition for treating cervical vertebra and lumbar vertebra diseases |
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| Title |
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| 王富春，等: "《中医自我诊病与用药》", 31 October 1991, 长春出版社 * |
| 谢天熙，等: "《中医内科临证自学必读》", 31 August 1988, 福建科学技术出版社 * |
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| CN105194592B (en) | 2019-03-05 |
| HK1214770A1 (en) | 2016-08-05 |
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