CN105181782B - The detecting system and detection method of a kind of array detection plate for ionic migration spectrometer - Google Patents
The detecting system and detection method of a kind of array detection plate for ionic migration spectrometer Download PDFInfo
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Abstract
The invention discloses a kind of detecting system and detection method of the array detection plate for ionic migration spectrometer, sub- detection faces therein are formed in an array manner, detecting system includes Ion transfer tube module, array detection plate module, across hindering amplification module, analog-to-digital conversion module and accessory module, improves signal to noise ratio, sensitivity and the resolution ratio of detection signal；The sub- detection faces of distance center are divided into one group by detection method apart from the sub- detection faces of identical first, carry out obtaining transit time and be modified, obtain the transit time average value of each group detection faces, as correction factor, with the correction factor to the transit time amendment of test substance after, the composition of material is determined again, can improve the accuracy of detection.
Description
Technical field
The present invention relates to Ion mobility spectrometry field, more particularly to a kind of array for ionic migration spectrometer to detect
The detecting system and detection method of plate.
Background technology
Ion mobility spectrometry (ion mobility spectrometry, IMS) is that occur in early 1970s
A kind of new gas phase separation and detection technique.Its core concept is to be come with the difference of Ion transfer time to different material progress
Distinguish, it is very high using the instrument detection sensitivity of Ion mobility spectrometry, it can detect nanogram level (1ng=10-9kg) even
It is pieck stage (1pg=10-12kg) material, chemical warfare agent, drugs, explosive and air can detect using the instrument of the technology
The materials such as pollutant, in airport security, battlefield is reconnoitred, environmental monitoring, industrial production etc. have important application.
An important part is transference tube in ion mobility spectrometry instrument, and transference tube passes through electrode and external electrical
Be connected so as to produce electric field inside it, electric-field intensity be typically chosen as needed between 150~1000V/cm certain is certain
Value, such as 300V/cm, ion drift is to ion detection plate under electric field action, so as to produce pulse current.In practical application, absolutely
Most of ion mobility spectrometry instruments use single channel ion detection plate, as Fig. 1 (a) be ion detection plate front, 71 be detection plate
Mounting hole, 72 be detection plate earthing outer rim, and 73 be ion detection face；Fig. 1 (b) is ion detection back, and 74 be detection faces
Leading point, 75 be detection plate outer rim leading point, and ion detection plate front and back is connected by " via ".But practical application
In, longitudinal electric field and transverse electric field are not uniform electric fields in transference tube, therefore ion is in electric field action pockety
Under, the Time Inconsistency of ion detection plate is drifted in, so as to cause the pulse current half-peak breadth that detects larger, pulse current width
Value is smaller, reduces the accuracy of detection of ion mobility spectrometry instrument.
The content of the invention
In view of this, the invention provides a kind of array detection plate, detecting system and inspection for ionic migration spectrometer
Survey method, sensitivity and the resolution ratio of ion mobility spectrometry instrument can be improved.
A kind of array detection plate for ion mobility spectrometry instrument, the substrate of the detection plate, which is adopted, to be made from an insulative material,
The positive edge of substrate sets front signal ground, and array detection faces are provided with the inside of the signal ground of front；
The array detection faces are made up of in an array manner the square sub- detection faces of N number of mutual insulating；It is sub two-by-two
Mutual insulating between detection faces；The N is at least 2；
The edge of the substrate back side of the array detection plate is provided with the reverse side signal ground electrically connected with front signal ground；
Each positive described sub- detection faces are correspondingly arranged the signal a being connected electrically leading point in the reverse side of substrate.
Preferably, the substrate is made of polytetrafluoroethylene (PTFE)；The array detection faces, front signal ground and reverse side letter
Number ground passes through the gold-plated formation after the substrate surface applies copper.
Preferably, the N takes 64.
Preferably, between front signal ground and reverse side signal ground and between sub- detection faces and corresponding signal leading point
Electrical connection is realized by via.
A kind of detecting system based on array detection plate, including across resistance amplification module, analog-to-digital conversion module and attached
Module；
It is described defeated from N number of signal leading point of array detection plate reception ion mobility spectrometry instrument across resistance amplification module
The N roads current signal gone out, as pulse ion electric current, Bing Jiangge roads pulse ion electric current are converted to by the way of capacitance integral
Voltage signal；
The analog-to-digital conversion module will be converted to from the analog form of the N roads pulse ion electric current received across resistance amplification module
Digital form；
The accessory module obtains average current after the analog-to-digital conversion module receives each road pulse ion electric current；Together
When, after calculating the transit time that ion mobility spectrometry instrument intermediate ion moves in each sub- detection faces from ion gate, obtain ion
The average mobility time；Determine to be input to the test substance of ion mobility spectrometry instrument according to average current and average transit time
Concentration and material composition.
Preferably, the model AFE0064 across resistance amplification module U1；AFE0064 pin 113 is to pin 128
And input of the pin 1 to pin 48 for the pulse ion electric current；Pin 105 and 104 is respectively reference voltage input
With negative reference voltage input, pin 112 is internal integrator common-mode voltage end, passes through electric capacity C31 decouplings to ground；The He of pin 83
Pin 84 is respectively the differential mode output end of oppisite phase and positive terminal of output channel 0；AFE0064 pin 77 and pin 78 is respectively defeated
Go out the differential mode output end of oppisite phase and positive terminal of passage 1；AFE0064 pin 98 is that output mode selects end, and connection+3.3V is to select
Take output channel 0 and output channel 1 whether synchronism output；Pin 92 connects+3.3V, so as to obtain output end after the data transfer ends
In tri-state；Pin 64 transmits the busy indication signal of reading to accessory module；Pin 66 receives the inside filter that accessory module provides
Wave control signal；Pin 67 receives the internal integrator reset signal that accessory module provides, to prevent from integrating saturation；The He of pin 68
69 pin receive integrator signal collection and the signal reseting controling signal of accessory module offer；Pin 70 receives accessory module and carried
The clock signal of confession；It is defeated to reset input channel counter and enabled output channel that pin 97 receives the signal that accessory module provides
Go out；Pin 93 is grounded to select integrator from low level to high level output；Pin 53,55,60,61,75,81,87,100,
106th, 108 pin meet+3.3V, and are decoupled respectively by electric capacity C8, C10, C12, C3, C14, C15, C16, C17, C18 to ground；Pin
49、51、52、54、59、62、65、71、73、74、76、79、80、82、85、86、90、91、99、101、102、103、107、109、
110 are connected to the ground；The pin of pin 56,57,58,63,72,88,89,111 is hanging；The pin state of pin 94,95,96 is corresponding 8 kinds
Integrating capacitor.
Preferably, the reference voltage of the accessory module is provided by ADR421, ADR421 pin 2 is power input,
External+5V power supplys, and decoupled by C32 to ground, with connecting power supply, ADR421 pins 6 are output end to ADR421 pins 4, output
2.5V, and by electric capacity C33 decouplings to ground, while series resistance R10, R9, R8 to be to carry out partial pressure, to obtain 2.25V and 0.85V
It is respectively supplied to AFE0064 105 pin and 104 pin.
Preferably, analog-to-digital conversion module uses 14 single channel conversion chip AD9240 of two panels, U2 and U3 are designated as；U2 and U3
Connected mode it is consistent, wherein U2 be AFE0064 output channel 0 provide conversion, U3 be AFE0064 output channel 1 provide
Conversion；By taking U2 as an example：U2 pin 41 and pin 42 is AD9240 input port, is connected respectively by resistance R1 with resistance R2
The positive differential mode output end of AFE0064 output ports 0 and anti-phase differential mode output end；U2 pin 32 is reference voltage end, and is led to
Electric capacity C3 and C4 is crossed to decouple to ground；U2 pin 31 and the short circuit of pin 33 are simultaneously grounded to select internal reference voltage 2.5V and guarantee
Zero-bias voltage；The decoupling network that U2 pin 36,37,39 is made up of electric capacity C5, C6, C7, C9 carries out decoupling；U2 pin
35 are grounded by resistance R3 to select AD9240 sample frequency；U2 pin 4 and pin 28 is power input, external+5V
Power supply, and pass through electric capacity C1 and C2 decoupling to ground；U2 pin 2 and pin 29 is simulation ground terminal, with connecting power supply；The He of pin 3
Pin 6 is digital power input, external+5V power supplys, and passes through electric capacity C20 and C21 decoupling to ground；Pin 1 and pin 5 are number
Word ground terminal, connection is digitally；U2 pin 7 receives the clock signal that accessory module provides；U2 pin 11,12,13,14,
15th, 16,17,18,19,20,21,22,23,24 be parallel output mouth, receives the numeral after the conversion of accessory module transmission respectively
Signal；U2 pin 25 provides to accessory module overflows indication signal；Pin 8,9,10,26,27,30,34,38,40,43,44
Vacantly；Power supply with digitally connected by resistance R4.
A kind of material concentration detection method based on array detection plate, by from N number of signal of the array detection plate
Leading point receives pulse ion electric current and is averaging, and draws total pulse current average value, ion mobility spectrometry is input to detect
The concentration of the test substance of instrument.
A kind of material composition detection method based on array detection plate, is comprised the following steps that：
Step 1, ion mobility spectrometry instrument is opened, be passed through standardizing chemical reagent, close ion gate, standard reagent is ionizing
Area is ionized, and a timer is set for each sub- detection faces；Ion gate is opened, while starts each timer, works as ion
When reaching sub- detection faces, stop corresponding timer, obtain the transit time of ion in each sub- detection faces；The ion gate is opened
Time control is opened between 100us~500us.
Step 2, center and array detection plate centre distance identical those sub- detection faces be divided into one group, to every group
In the Ion transfer time corresponding to all sub- detection faces average, obtain the Ion transfer time average of the group；
Step 3, with apart from Ion transfer time average t corresponding to the nearest one group of sub- detection faces in sub- detection faces centerAFor when
Between benchmark, respectively divided by other each groups Ion transfer time average, obtain the correction factor P of each group of transit timeX；
Wherein tXRepresent the other groups of sub- detection faces except one group of closest sub- detection faces；
Step 4, repeat step 1 to 3, correction time Coefficient Mean is obtained after multiple averaging
Step 5, chemical reagent M to be detected is passed through, records the transit time that each sub- detection faces detect, and according to step 2
Method calculate the sub- detection faces of each group Ion transfer time average, be multiplied by correction time Coefficient Mean respectivelyObtain each group
Ion transfer time normalization value；
Step 6, the Ion transfer time normalization value to each group are averaging, and obtain the average mobility time of ion, accordingly
Determine chemical reagent M to be detected material composition.
The present invention has the advantages that：
(1) single formula ion detection plate is improved to array detection plate by the present invention, and devises coherent signal processing electricity
Road, backoff algorithm is derived, improve signal to noise ratio, sensitivity and the resolution ratio of detection signal.
(2) the sub- detection faces of distance center are divided into one group by detection method of the invention apart from the sub- detection faces of identical first,
Carry out obtaining transit time and be modified, obtain the transit time average value of each group detection faces, as correction factor, corrected with this
After coefficient is to the transit time amendment of test substance, then the composition of material is determined, the accuracy of detection can be improved.
Brief description of the drawings
Fig. 1 is existing single formula ion detection plate schematic diagram；
Fig. 2 is existing ion migration tube structure schematic diagram；
Fig. 3 (a) is transference tube electric field intensity inside high distribution schematic diagram；
Fig. 3 (b) is detection pulse current intensity schematic diagram in transference tube；
Fig. 4 (a) is the multichannel ion detection plate positive structure schematic of the present invention；
Fig. 4 (b) is the multichannel ion detection plate reverse structure schematic of the present invention；
Fig. 5 is across resistance amplification module and analog-to-digital conversion module circuit connection diagram；
Fig. 6 is accessory module structural representation.
Wherein, 1- drier, 2- air pumps, 3- electrode slices, 4- radioactive sources, 5- ion gates, 6- grid screens, 60- migration ions,
7- ion detection plates, 8- ventholes, 9- pulse current lead-out wires, 71- mounting holes, 72- fronts signal ground, the detection of 73- arrays
Face, 74- signals leading point, 75- reverse side signal grounds leading point, 76- reverse side signal grounds.
Embodiment
The present invention will now be described in detail with reference to the accompanying drawings and examples.
As shown in Figure 2,1 is drier to Ion transfer module in ion mobility spectrometry instrument, and 2 be air pump, and 3 be electrode, 4
It is ion gate for Ni63 radioactive sources, 5,6 be grid screen, and 7 be ion detection plate, and 8 be gas outlet, and 9 be pulse current lead-out wire.By
Ion mobility spectrometry relevant knowledge understands, when the external voltage in certain gradient increasing or decreasing of electrode slice 3, in transference tube
Interior formation electric field, the ray ionization that chemical substance to be detected is launched by Ni63 radioactive sources 4 first in ionization region, form band ionization
Son, the periodic switching pulses of ion gate 5 are controlled, when ion gate 5 is opened, charged ion produces drift under electric field action,
And detect pulse current on ion detection plate 7.In the case of electric field relatively low (E ＜ 1000V/cm), being averaged for ion is moved
Move speed v and electric-field intensity E and meet following relation：
V=K × E (1)
In formula, K is ionic mobility (definition of mobility refers to the migration velocity of the ion in the case where unit electric field acts on), with
The ion is relevant with the molecular property of gas in transference tube.When migration intraductal pressure and the timing of temperature one, K values are certain
Value.
Formula (1) shows that Ion transfer speed depends on transference tube internal electric field.And transference tube internal electric field is such as
Shown in accompanying drawing 3 (a), ordinate E represents electric-field intensity, and abscissa x represents electric-field intensity test point and the distance in migration tube axle center.
Ideally, the field strength distribution in transference tube such as a curves in Fig. 3 (a), i.e. electric-field intensity are a fixed value；However,
Because electric-field intensity can decay with the increase of distance, the b in the actual field strength distribution such as Fig. 3 (a) inside transference tube is bent
Line, it is an attenuation curve, i.e. migration tube hub electric field is stronger, and the electric field close to migration inside pipe wall is weaker, so due to electric field
The size distribution of intensity is inconsistent, and causing identical ion, the ion of core moves in transference tube in transition process
Move comparatively fast, and the Ion transfer speed close to Ion transfer inside pipe wall is slower.So that identical ion reaches ion detection
The Time Inconsistency of plate 7, the pulse current half-peak breadth that ion detection plate 7 detects is added, as shown in Fig. 3 (b) right figures, a is
The pulse current that ideally ion detection plate detects, b are the pulse current detected under actual conditions.
The present invention array ion detection plate as shown in Figure 4, array detection faces 73 by multiple mutual insulatings side
The sub- detection faces of shape are formed in an array manner, two-by-two mutual insulating between sub- detection faces.The background of array ion detection plate
Material is the Teflon of high insulating coefficient, and Fig. 4 (a) is detection plate front, wherein 71 be mounting hole, inner wall of the hole installing applies copper plating
Gold, reduce equivalent resistance so that ion detection plate front and back side good connection, 72 be ion detection plate earthing frame, after applying copper
Gold-plated to reduce equivalent resistance, raising signal quality, 73 be array detection faces, and gold-plated after deposited copper, 8 rows 8 row are uniformly distributed altogether
64,64 sub- detection faces are in the same size, and long and width is 3mm, and sub- detection interplanar distance is 1mm；Fig. 4 (b) is ion detection
Back, wherein 74 be pulsed current signal leading point, totally 64 tunnel, 75 be reverse side signal ground leading point.64 sub- detection faces 73
It is connected respectively by " via " with 64 pulsed current signal leading points 74, via diameter 0.2mm.
Across resistance amplification module using the AFE0064 for being exclusively used in the detection of medical x-ray flat board, its reference voltage is by reference voltage core
Piece ADR421 is provided.It is described as follows with reference to accompanying drawing 5：AFE0064 pin 113,114 ..., 128 and pin 1,2 ..., 48
For 64 road inputs, connect respectively the road current signal i1, i2 of ion detection plate 64 ..., i64；The AFE0064 He of pin 105
104 be respectively that reference voltage input and negative reference voltage input, reference voltage are provided by ADR421, ADR421 pin
2 be power input, external+5V power supplys, and is decoupled by C32 to ground, ADR421 pins 4 with connecting power supply, ADR421 pins 6
For output end, 2.5V is exported, and by electric capacity C33 decouplings to ground, while series resistance R10, R9, R8 to be to carry out partial pressure, with
AFE0064 105 pin and 104 pin are respectively supplied to 2.25V and 0.85V；AFE0064 pin 112 is total to for internal integrator
Mode voltage end, pass through electric capacity C31 decouplings to ground；AFE0064 pin 83 and pin 84 is respectively the differential mode output of output channel 0
End of oppisite phase and positive terminal；AFE0064 pin 77 and pin 78 is respectively the differential mode output end of oppisite phase and positive of output channel 1
End；AFE0064 pin 98 is that output mode selects end, and connection+3.3V (is synchronously referred to here with choosing " synchronization " output
AFE0064 output channel 0 and output channel 1 exports simultaneously)；AFE0064 pin 92 connects+3.3V, is passed so as to obtain data
Output is in tri-state after defeated end；AFE0064 pin 64 is output signal pin, and connection FPGA is simultaneously numerous to FPGA transmission readings
Busy indication signal；AFE0064 pin 66 connects FPGA and provides internal filter control signal by FPGA；AFE0064 pin
67 connection FPGA simultaneously provide internal integrator reset signal by FPGA, to prevent from integrating saturation；The AFE0064 pin of pin 68 and 69
It is all connected with FPGA and integrator signal collection and signal reseting controling signal is provided respectively by FPGA；Pin 70 connect FPGA and by
DPGA provides clock signal；Pin 97 connects FPGA and provides signal by FPGA to reset input channel counter and enabled output
Passage exports；Pin 93 is grounded to select integrator from low level to high level output；Pin 53,55,60,61,75,81,87,
100th, 106,108 pin meet+3.3V, and are decoupled respectively by electric capacity C8, C10, C12, C3, C14, C15, C16, C17, C18 to ground；
Pin 49,51,52,54,59,62,65,71,73,74,76,79,80,82,85,86,90,91,99,101,102,103,107,
109th, 110 it is connected to the ground；The pin of pin 56,57,58,63,72,88,89,111 is hanging；8 kinds of integrating capacitors may be selected in AFE0064,
Corresponding 8 kinds of quantity of electric charge range of receiving, respectively by the pin Determines of pin 94,95,96,94,95,96 pins connect herein
Ground.The voltage Un of the n-th tunnel of correspondence detection plate of AFE0064 output can be tried to achieve by following formula, and C represents integrating capacitor, and in represents n-th
The pulse current that road detection plate receives, Qr represent electric charge reception amount, and Upm represents the difference of reference voltage and negative reference voltage
Analog-to-digital conversion module uses 14 single channel conversion chip AD9240 of two panels, such as the U2 and U3 in accompanying drawing 5.With reference to attached
Fig. 5 be described as follows (U2 is consistent with U3 connected mode, unlike U2 be AFE0064 output channel 0 conversion is provided, U3 is
AFE0064 output channel 1 provides conversion, here by taking U2 as an example)：U2 pin 41 and 42 is AD9240 input port, point
The positive differential mode output end of AFE0064 output ports 0 and anti-phase differential mode output end are not connected with R2 by R1；U2 pin 32 is
Reference voltage end, and decoupled by electric capacity C3 and C4 to ground；U2 pin 31 and the short circuit of pin 33 are simultaneously grounded to select internal ginseng
Examine voltage 2.5V and ensure zero-bias voltage；The decoupling network that U2 pin 36,37,39 is made up of electric capacity C5, C6, C7, C9
Carry out decoupling；U2 pin 35 is grounded by resistance R3 to select AD9240 sample frequency；U2 pin 4 and pin 28 is electricity
Source input, external+5V power supplys, and pass through electric capacity C1 and C2 decoupling to ground；U2 pin 2 and pin 29 is simulation ground terminal, even
With connecing power supply；Pin 3 and pin 6 are digital power input, external+5V power supplys, and pass through electric capacity C20 and C21 decoupling to ground；
Pin 1 and pin 5 are digital ground terminal, and connection is digitally；U2 pin 7 connects FPGA and provides clock signal by FPGA；U2's
Pin 11,12,13,14,15,16,17,18,19,20,21,22,23,24 be parallel output mouth, connect respectively FPGA and to
Data signal after FPGA transmission conversions；U2 pin 25, which connects FPGA and provided to FPGA, overflows indication signal；Pin 8,9,
10th, 26,27,30,34,38,40,43,44 is hanging；Power supply with digitally connected by resistance R4.
Accessory module includes power module, level switch module, field programmable gate array (FPGA), sound and light alarm
Deng as shown in Figure 6.Power module offer+5V ,+3.3V ,+2.5V ,+1.2V, level switch module be used for by AD9240+
5V signals and FPGA+3.3V signals switch over, FPGA offers AFE0064 STI, CLK, SHR, SHS, IRST, INTG letter
Number, and receive the eoc signal of AFE0064 transmission, there is provided two panels AD9240 CLKA, CLKB signal, and receive two panels AD9240
OA, A-B1, A-B2, A-B3, A-B4, A-B5, A-B6, A-B7, A-B8, A-B9, A-B10, A-B11, A-B12, A-B13, A-
B14 and OB, B-B1, B-B2, B-B3, B-B4, B-B5, B-B6, B-B7, B-B8, B-B9, B-B10, B-B11, B-B12, B-B13,
B-B14；Sound and light alarm refers to send sound and light alarm when chemical substance concentration to be detected is exceeded or operation irregularity.
The correction algorithm for improving ion detection plate accuracy of detection is given below：
The first step：Transit time amendment
1st, open ion mobility spectrometry instrument, be passed through standardizing chemical reagent, close ion gate, standard reagent ionization region from
Ion gate is opened after sonization, the opening time is about 300us, starts simultaneously at timing, ion is in drift region through moving after a while
Ion detection plate is moved to, stops timing after the n-th tunnel ion detection face detects pulse current, obtains transit time tn, due to
The being distributed symmetrically property in ion detection face, has in theory：
t28=t29=t37=t36(4)；
t20=t21=t30=t38=t45=t44=t35=t27(5)；
t19=t22=t46=t43(6)；
t12=t13=t31=t39=t52=t53=t34=t26(7)；
t11=t14=t23=t47=t54=t51=t42=t18(8)；
t10=t15=t55=t50(9)；
t4=t5=t32=t40=t61=t60=t33=t25(10)；
t3=t6=t24=t48=t62=t59=t41=t17(11)；
t2=t7=t16=t56=t63=t58=t49=t9(12)；
t1=t8=t64=t57(13)；
2nd, 64 way detection faces can be divided into by 10 groups, respectively A, B, C, D, E, F, G, H, I, J according to formula (4) to formula (13)
Group, every group is averaged：
3rd, after obtaining 10 groups of transit times, with tAFor time reference, the correction factor of 10 groups of transit times of definition：
Wherein, X=(A, B ..., J).
4th, repeat the above steps, correction time coefficient is obtained after multiple averaging
5th, chemical reagent M to be detected is passed through, the transit time that the 64 tunnel ion detection faces of record detect, and according to formula (14)
The average value of 10 groups of transit times is obtained to formula (23), it is assumed that the average value of Group X transit time isWhen then to Ion transfer
Between normalize after have：
6th, the average mobility time of ion is calculated, calculation formula is as follows：
Second step：Pulse current size amendment
1st, FPGA reads the voltage signal Un after current/voltage-converted and analog-to-digital conversion, and formula (2) is carried out at differential
Reason, can obtain the size of current that ion detection plate detects is
2nd, repeatedly it is passed through chemical substance to be detected and the current average of each passage is obtained according to formula (27), obtains respectively
The size of current of 64 passages, then arithmetic average obtain total pulse current average value, calculation formula is as follows：
3rd step：Revised transit time and pulse current size is tried to achieve according to formula (26) and formula (28), and according to this
It can determine that the material composition and substantially concentration of chemical substance to be detected.
In summary, presently preferred embodiments of the present invention is these are only, is not intended to limit the scope of the present invention.
Within the spirit and principles of the invention, any modification, equivalent substitution and improvements made etc., it should be included in the present invention's
Within protection domain.
Claims (5)
- A kind of 1. detecting system of array detection plate for ionic migration spectrometer, it is characterised in that the array detection plate Substrate adopt and be made from an insulative material, the positive edge of substrate sets front signal ground (72), on the inside of front signal ground (72) It is provided with array detection faces (73)；The array detection faces (73) are made up of in an array manner the square sub- detection faces of N number of mutual insulating；It is sub two-by-two Mutual insulating between detection faces；The N is at least 2；The edge of the substrate back side of the array detection plate is provided with the reverse side signal ground electrically connected with front signal ground (72) (76)；Each positive described sub- detection faces are correspondingly arranged the signal a being connected electrically leading point in the reverse side of substrate (74)；The substrate is made of polytetrafluoroethylene (PTFE)；The array detection faces (73), front signal ground (72) and reverse side signal Ground (76) passes through the gold-plated formation after the substrate surface applies copper；Between front signal ground (72) and reverse side signal ground (76) and between sub- detection faces and corresponding signal leading point (74) Electrical connection realized by via；The detecting system is included across resistance amplification module, analog-to-digital conversion module and accessory module；It is described defeated from N number of signal leading point (74) reception ion mobility spectrometry instrument of the array detection plate across resistance amplification module The N roads current signal gone out, as pulse ion electric current, Bing Jiangge roads pulse ion electric current are converted to by the way of capacitance integral Voltage signal；The analog-to-digital conversion module will be converted to numeral from the analog form of the N roads pulse ion electric current received across resistance amplification module Form；The accessory module obtains average current after the analog-to-digital conversion module receives each road pulse ion electric current；Meanwhile count After calculating the transit time that ion mobility spectrometry instrument intermediate ion moves in each sub- detection faces from ion gate, being averaged for ion is obtained Transit time；According to average current and average transit time determine to be input to the concentration of the test substance of ion mobility spectrometry instrument and Material composition；The described model AFE0064 across resistance amplification module U1；AFE0064 pin 113 is to pin 128 and pin 1 to drawing Pin 48 is the input of the pulse ion electric current；Pin 105 and 104 is respectively reference voltage input and negative reference voltage Input, pin 112 are internal integrator common-mode voltage end, pass through electric capacity C31 decouplings to ground；Pin 83 and pin 84 are respectively The differential mode output end of oppisite phase and positive terminal of output channel 0；AFE0064 pin 77 and pin 78 is respectively the difference of output channel 1 Mould exports end of oppisite phase and positive terminal；AFE0064 pin 98 is that output mode selects end, and connection+3.3V is to choose output channel 0 With output channel 1 whether synchronism output；Pin 92 connects+3.3V, so that output is in tri-state after obtaining the data transfer ends；Draw Pin 64 transmits the busy indication signal of reading to accessory module；Pin 66 receives the inside filter control signal that accessory module provides； Pin 67 receives the internal integrator reset signal that accessory module provides, to prevent from integrating saturation；The pin of pin 68 and 69 receives The integrator signal collection and signal reseting controling signal that accessory module provides；Pin 70 receives the clock letter that accessory module provides Number；Pin 97 receives the signal that accessory module provides and exported with resetting input channel counter and enabled output channel；Pin 93 Ground connection is to select integrator from low level to high level output；The pin of pin 53,55,60,61,75,81,87,100,106,108 connects + 3.3V, and decoupled respectively by electric capacity C8, C10, C12, C3, C14, C15, C16, C17, C18 to ground；Pin 49,51,52, 54th, 59,62,65,71,73,74,76,79,80,82,85,86,90,91,99,101,102,103,107,109,110 it is connected to Ground；The pin of pin 56,57,58,63,72,88,89,111 is hanging；The corresponding 8 kinds of integrating capacitors of the pin state of pin 94,95,96.
- 2. detecting system as claimed in claim 1, it is characterised in that the reference voltage of the accessory module is carried by ADR421 Pin 2 for, ADR421 is power input, external+5V power supplys, and is decoupled by C32 to ground, ADR421 pins 4 and connect electricity Source, ADR421 pins 6 are output end, export 2.5V, and by electric capacity C33 decouplings extremely, while series resistance R10, R9, R8 To carry out partial pressure, to obtain 105 pin and 104 pin that 2.25V and 0.85V is respectively supplied to AFE0064.
- 3. detecting system as claimed in claim 1 or 2, it is characterised in that analog-to-digital conversion module uses 14 single channels of two panels Conversion chip AD9240, is designated as U2 and U3；U2 is consistent with U3 connected mode, and the output channel 0 that wherein U2 is AFE0064 provides Conversion, the output channel 1 that U3 is AFE0064 provide conversion；By taking U2 as an example：U2 pin 41 and pin 42 is AD9240 input Port, connect positive differential mode output end and the output of anti-phase differential mode of AFE0064 output ports 0 with resistance R2 by resistance R1 respectively End；U2 pin 32 is reference voltage end, and decoupled by electric capacity C3 and C4 to ground；U2 pin 31 and the short circuit of pin 33 simultaneously connect Ground with select internal reference voltage 2.5V and ensure zero-bias voltage；U2 pin 36,37,39 passes through electric capacity C5, C6, C7, C9 The decoupling network of composition carries out decoupling；U2 pin 35 is grounded by resistance R3 to select AD9240 sample frequency；U2's draws Pin 4 and pin 28 are power input, external+5V power supplys, and pass through electric capacity C1 and C2 decoupling to ground；U2 pin 2 and pin 29 be simulation ground terminal, with connecting power supply；Pin 3 and pin 6 are digital power input, external+5V power supplys, and pass through electric capacity C20 and C21 decouplings are extremely；Pin 1 and pin 5 are digital ground terminal, and connection is digitally；U2 pin 7 receives accessory module and provided Clock signal；U2 pin 11,12,13,14,15,16,17,18,19,20,21,22,23,24 is parallel output mouth, point Not Jie Shou accessory module transmission conversion after data signal；U2 pin 25 provides to accessory module overflows indication signal；Draw Pin 8,9,10,26,27,30,34,38,40,43,44 is hanging；Power supply with digitally connected by resistance R4.
- 4. a kind of material concentration detection method of the array detection plate based on described in claim 1, it is characterised in that will be from N number of signal leading point (74) of the array detection plate receives pulse ion electric current and is averaging, and show that total pulse current is put down Average, to detect the concentration for the test substance for being input to ion mobility spectrometry instrument.
- A kind of 5. material composition detection method of the array detection plate based on described in claim 1, it is characterised in that specific Step is as follows：Step 1, ion mobility spectrometry instrument is opened, be passed through standardizing chemical reagent, close ion gate (5), standard reagent is ionizing Area is ionized, and a timer is set for each sub- detection faces；Open ion gate (5), while start each timer, when from When son reaches sub- detection faces, stop corresponding timer, obtain the transit time of ion in each sub- detection faces；The ion gate (5) opening time control is between 100us~500us；Step 2, center and array detection plate centre distance identical those sub- detection faces be divided into one group, to institute in every group There is the Ion transfer time corresponding to sub- detection faces to average, obtain the Ion transfer time average of the group；Step 3, with apart from Ion transfer time average t corresponding to the nearest one group of sub- detection faces in sub- detection faces centerAFor time base The Ion transfer time average of standard, difference divided by other each groups, obtains the correction factor P of each group of transit timeX；Wherein tXRepresent the other groups of sub- detection faces except one group of closest sub- detection faces；Step 4, repeat step 1 to 3, correction time Coefficient Mean is obtained after multiple averaging；Step 5, chemical reagent M to be detected is passed through, records the transit time that each sub- detection faces detect, and according to the side of step 2 Method calculates the Ion transfer time average of the sub- detection faces of each group, is multiplied by correction time Coefficient Mean respectivelyObtain the ion of each group Transit time normalized value；Step 6, the Ion transfer time normalization value to each group are averaging, and are obtained the average mobility time of ion, are determined therefrom that Chemical reagent M to be detected material composition.
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| CN107976585A (en) * | 2017-12-29 | 2018-05-01 | 中国电力科学研究院有限公司 | A kind of ion flow density measurement system |
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Effective date of registration: 20171117 Address after: 443003 No. 13 Lanzhou Road, Gaoxin District, Hubei, Yichang Patentee after: CSIC ANPEL Instrument Co. Ltd. (Hubei) Address before: 443003 Shengli Road, Hubei, Yichang, No. three, No. 58 Patentee before: China Shipbuilding Industry Group Corporation No.710 Research Institute |