CN105181426A - Recovery device for suction nozzle and dyeing machine - Google Patents
Recovery device for suction nozzle and dyeing machine Download PDFInfo
- Publication number
- CN105181426A CN105181426A CN201510737105.XA CN201510737105A CN105181426A CN 105181426 A CN105181426 A CN 105181426A CN 201510737105 A CN201510737105 A CN 201510737105A CN 105181426 A CN105181426 A CN 105181426A
- Authority
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- China
- Prior art keywords
- suction nozzle
- axis
- axle
- sample needle
- slipping mechanism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000004043 dyeing Methods 0.000 title claims abstract description 28
- 238000011084 recovery Methods 0.000 title abstract 5
- 230000007246 mechanism Effects 0.000 claims abstract description 84
- 239000002699 waste material Substances 0.000 claims abstract description 23
- 230000000149 penetrating effect Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 description 7
- 238000005516 engineering process Methods 0.000 description 6
- 239000010410 layer Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 210000002919 epithelial cell Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 238000003795 desorption Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000011268 retreatment Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 210000000270 basal cell Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 208000019065 cervical carcinoma Diseases 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000005693 optoelectronics Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Fiber Materials (AREA)
Abstract
The invention discloses a recovery device for a suction nozzle. The recovery device comprises a sample-adding needle, a suction nozzle, a baffle base, a waste box, a Z1 axis bracket and a Z1 axis driving mechanism, wherein the baffle base is fixedly arranged at the bottom end of the Z1 axis bracket; the sample-adding needle is in sliding fit with the Z1 axis bracket along the Z axis direction; the Z1 axis driving mechanism is in driving connection with the sample-adding needle and is used for driving the sample-adding needle to vertically slide; the sample-adding needle is sleeved on the baffle base in a sliding form; correspondingly, the baffle base is provided with a penetrating hole, into which the sample-adding needle can be penetrated; the top end of the suction nozzle is detachably sleeved on the bottom end of the sample-adding needle; the top end of the suction nozzle is in resisting fit with the penetrating hole; the waste box is used for recovering the suction nozzle. The invention also discloses a dyeing machine adopting the recovery device for the suction nozzle. The recovery device for the suction nozzle can effectively save space.
Description
Technical field
The present invention relates to cell pathology detection technique, particularly relate to suction nozzle retracting device and overflow dyeing machine.
Background technology
Liquid based cytology test (Liquid-BasedCytologyTest is called for short " LCT ") technology is mainly used in cervical cytology and detects, and is particularly useful for the examination of cervical carcinoma.
Its principle of work is: be also all eluted to special sampler scraping cervical exfoliated cell and fill in the plastic bottle of cell-preservation liquid, deliver to laboratory, cell mass depolymerization is made after vibration rod is even, conserving liquid containing cell specimen is through centrifugation, make the magazins' layout such as cell fragment, blood, mucus and the leucocyte in cervical epithelial cells wherein and sample, obtain pure cervical epithelial cells, by cell transfer techniques, cervical epithelial cells is transferred to thin-layer cell layer microslide being made diameter 13mm, then rinse dyeing.These processes have controlled automatically by system, can be called to complete under the work of overflow dyeing machine, finally by diagosis make diagnosis by TBS under the microscope after technician's mounting.
Advantage is: the cellular layer made by LCT technology becomes monolayer distribution, clear background, is convenient to observe, and loss is low.
External LCT technology is based on AutoCyto (U.S. company BD production), although this checkout equipment slice-making quality is effective, price is higher, and Expenses of laboratory examination is expensive, and maintenance not in time, is not suitable for large-scale popularization at home.In the recent period, more domestic companies also develop the liquid basal cell thin layer dyeing machine of applicable national conditions, as the LCT checkout equipment (application number is a kind of dyeing machine of 2007100272504 and the method for film-making dyeing) of Guangzhou An Biping company, but from clinical test results, still very big-difference is there is compared with external LCT technology, slice-making quality differs greatly, be mainly reflected in: after suction nozzle fluid injection being installed to sample needle, need to arrange the support getting suction nozzle in addition, take larger space and position, and, the position that suction nozzle is removed is fixed, after being taken out by support, formation is piled up, hinder suction nozzle to reclaim flexibly.
Summary of the invention
In order to overcome the deficiencies in the prior art, an object of the present invention is to provide and effectively can saves space-efficient suction nozzle retracting device.
Two of object of the present invention is to provide the overflow dyeing machine adopting described suction nozzle retracting device.
An object of the present invention realizes by the following technical solutions:
Suction nozzle retracting device, comprise sample needle, suction nozzle, block seat, waste product box, Z1 bracing strut and Z1 axle driving mechanism, block seat is fixedly arranged on the bottom of Z1 bracing strut, sample needle is snug fit at Z1 bracing strut along Z-direction, and Z1 axle driving mechanism is for driving the vertical slippage of sample needle, and this sample needle slides and is connected to block seat, accordingly, block seat has the perforation penetrated for sample needle, and suction nozzle top is socketed on the bottom of sample needle removably, and this suction nozzle top is used for supporting with perforation coordinating; Waste product box is for reclaiming suction nozzle.
Preferably, bore a hole as circular hole, suction nozzle top is cylindrical, and the diameter of perforation is less than the diameter on suction nozzle top.
Two of object of the present invention realizes by the following technical solutions:
Adopt the overflow dyeing machine of described suction nozzle retracting device, comprise worktable and be all installed on this worktable for the just right scratch diskette of dyeing pin, for the specimen holder just right with sample needle, for the suction nozzle seat just right with sample needle and four-axle linked mechanism, four-axle linked mechanism has the X-axis slipping mechanism along the slippage of worktable X-direction, be installed on X-axis slipping mechanism and along the Y-axis slipping mechanism of worktable Y direction slippage, be installed on Y-axis slipping mechanism and along the slippage of worktable Z-direction Z1 axle slipping mechanism and be installed on Y-axis slipping mechanism and the Z2 axle slipping mechanism be slidably matched along worktable Z-direction, sample needle is installed on Z1 axle slipping mechanism, Z2 axle slipping mechanism is provided with dyeing pin, waste product box is installed on worktable.
Preferably, X-axis slipping mechanism comprises X-axis slide rail and X-axis driving mechanism, Y-axis slipping mechanism comprises Y-axis slide rail and Y-axis driving mechanism, Z1 axle slipping mechanism comprises described Z1 bracing strut and described Z1 axle driving mechanism, Z2 axle slipping mechanism comprises Z2 bracing strut and Z2 axle driving mechanism, Y-axis slide rail and X-axis slide rail are slidably matched, and Z1 bracing strut and Z2 bracing strut are slidably matched with Y-axis slide rail respectively, and dyeing pin is installed on Z2 bracing strut.
Compared to existing technology, beneficial effect of the present invention is:
Sample needle of the present invention, under the effect of Z1 axle driving mechanism, can make suction nozzle top be stopped by block seat, cannot follow sample needle and continue up, thus squeezed taking off of taking advantage of a situation drops down onto waste product box.Because this block seat is fixed on Z1 bracing strut, do not need to set up the support getting suction nozzle separately, effectively can save space;
Overflow dyeing machine of the present invention can drive Z1 bracing strut to move by four-axle linked mechanism, thus suction nozzle is fallen into from the position in varying level direction above waste product box, avoid building up heap high, thus can't affect the operation of desorption mouth next time, also need not topple over waste product box continually; Certainly, all fall into from the position of identical horizontal direction above waste product box if suction nozzle is each, also can avoid building up heap high, because sample needle possesses the ability of Z-direction movement, when sample needle drive suction nozzle comes off suction nozzle in higher position, suction nozzle falls in waste product box and generation bounce is flicked.Because the position that suction nozzle comes off is not fixing, the suction nozzle as long as about position that sample needle gets back to waste product box just can come off, it is comparatively large therefore to move back the space of unloading the suction nozzle that comes off, and operates more flexible; In addition, only need sample needle under the drive of X-axis driving mechanism and Z1 axle driving mechanism, just can complete suction nozzle and come off, therefore its retreatment suction nozzle required time is shorter, is more conducive to save the film-making time.
Accompanying drawing explanation
Fig. 1 is the structural representation of suction nozzle retracting device of the present invention;
Fig. 2 is the schematic diagram that the suction nozzle of suction nozzle retracting device of the present invention drops to waste product box;
Fig. 3 is the front view of overflow dyeing machine of the present invention;
Fig. 4 is the vertical view of Fig. 3;
Fig. 5 is the left view of Fig. 3.
In figure: 1, sample needle; 2, suction nozzle; 3, block seat; 4, waste product box; 5, four-axle linked mechanism; 51, X-axis slipping mechanism; 52, Y-axis slipping mechanism; 53, Z1 axle slipping mechanism; 531, Z1 bracing strut; 532, Z1 axle driving mechanism; 54, Z2 axle slipping mechanism; 6, worktable; 7, scratch diskette; 8, specimen holder; 9, suction nozzle seat; 10, dye pin.
Embodiment
Below, by reference to the accompanying drawings and embodiment, the present invention is described further:
Suction nozzle retracting device as shown in Fig. 1 ~ 2, comprise sample needle 1, suction nozzle 2, block seat 3, waste product box 4, Z1 bracing strut 531 and Z1 axle driving mechanism 532, block seat 3 is fixedly arranged on the bottom of Z1 bracing strut 531, sample needle 1 is snug fit at Z1 bracing strut 531 along Z-direction, Z1 axle driving mechanism 532 is for driving the vertical slippage of sample needle 1, this sample needle 1 slides and is connected to block seat 3, accordingly, block seat 3 has the perforation penetrated for sample needle 1, suction nozzle 2 top is socketed on the bottom of sample needle 1 removably, and this suction nozzle 2 top is used for supporting with perforation coordinating, suction nozzle 2 is made to pass perforation thus to come off from sample needle 1, waste product box 4 is for reclaiming suction nozzle 2.
Sample needle 1, under the effect of Z1 axle driving mechanism 532, can make suction nozzle 2 top be stopped by block seat 3, cannot follow sample needle 1 and continue up, thus squeezed taking off of taking advantage of a situation drops down onto waste product box 4.Because this block seat 3 is fixed on Z1 bracing strut 531, do not need to set up the support getting suction nozzle 2 separately, effectively can save space.
In order to sample needle 1 cross-under on block seat 3 more reposefully, the suction nozzle 2 that comes off of simultaneously effectively retreating again, the perforation of this example is circular hole, and suction nozzle 2 top is cylindrical, and the diameter of perforation is less than the diameter on suction nozzle 2 top.
As seen in figures 3-5, adopt the overflow dyeing machine of described suction nozzle retracting device, comprise worktable 6 and be all installed on this worktable 6 for the just right scratch diskette 7 of dyeing pin 10, for the specimen holder 8 just right with sample needle 1, for the suction nozzle seat 9 just right with sample needle 1 and four-axle linked mechanism 5, four-axle linked mechanism 5 has the X-axis slipping mechanism 51 along the slippage of worktable 6X direction of principal axis, be installed on X-axis slipping mechanism 51 and the Y-axis slipping mechanism 52 of Y direction slippage along worktable 6, be installed on Y-axis slipping mechanism 52 and along the Z-direction slippage of worktable 6 Z1 axle slipping mechanism 53 and be installed on Y-axis slipping mechanism 52 and the Z2 axle slipping mechanism 54 be slidably matched along the Z-direction of worktable 6, so, sample needle 1 can along X, Y, Z1 axle moves, dyeing pin 10 can along X, Z2 axle moves.Sample needle 1 is installed on Z1 axle slipping mechanism 53, Z2 axle slipping mechanism 54 and is provided with dyeing pin 10; Waste product box 4 is installed on worktable 6.
Sample needle 1 enters specimen holder 8 again and carries out suction sample after drawing suction nozzle 2, four-axle linked mechanism 5 is respectively dyeing pin 10 and sample needle 1 provides the flexible locomotivity of three axles, with accurate alignment work dish 7, suction nozzle seat 9 and specimen holder 8 respectively.Can control device be coordinated, realize more full automatic LCT and operate.
Exemplarily, X-axis slipping mechanism 51 comprises X-axis slide rail and X-axis driving mechanism, Y-axis slipping mechanism 52 comprises Y-axis slide rail and Y-axis driving mechanism, Z1 axle slipping mechanism 53 comprises Z1 bracing strut 531 and Z1 axle driving mechanism 532, Z2 axle slipping mechanism 54 comprises Z2 bracing strut and Z2 axle driving mechanism, and Y-axis slide rail and X-axis slide rail are slidably matched, and Z1 bracing strut 531 and Z2 bracing strut are slidably matched with Y-axis slide rail respectively, sample needle 1 is installed on Z1 bracing strut 531, and dyeing pin 10 is installed on Z2 bracing strut.Wherein, X-axis driving mechanism, Y-axis driving mechanism, Z1 axle driving mechanism 532, Z2 axle driving mechanism all can adopt band transmission to realize in conjunction with motor, certainly, can set up the precision that the elements such as shaft coupling, slide block, optoelectronic switch carry out sliding and lifting.
The overflow dyeing machine of this example can drive Z1 bracing strut 531 to move by four-axle linked mechanism 5, thus suction nozzle 2 is fallen into from diverse location above waste product box 4, avoids building up heap high, thus affects the operation of desorption mouth 2 next time, also need not topple over waste product box 4 continually.Because the position that suction nozzle 2 comes off is not fixing, the suction nozzle 2 as long as about position that sample needle 1 gets back to waste product box 4 just can come off, it is comparatively large therefore to move back the space of unloading the suction nozzle 2 that comes off, and operates more flexible; In addition, only need sample needle 1 under the drive of X-axis driving mechanism and Z1 axle driving mechanism 532, just can complete suction nozzle 2 and come off, therefore its retreatment suction nozzle 2 required time is shorter, is more conducive to save the film-making time.
To one skilled in the art, according to technical scheme described above and design, other various corresponding change and deformation can be made, and all these change and deformation all should belong within the protection domain of the claims in the present invention.
Claims (4)
1. suction nozzle retracting device, it is characterized in that, comprise sample needle, suction nozzle, block seat, waste product box, Z1 bracing strut and Z1 axle driving mechanism, block seat is fixedly arranged on the bottom of Z1 bracing strut, sample needle is snug fit at Z1 bracing strut along Z-direction, Z1 axle driving mechanism is for driving the vertical slippage of sample needle, this sample needle slides and is connected to block seat, accordingly, block seat has the perforation penetrated for sample needle, suction nozzle top is socketed on the bottom of sample needle removably, and this suction nozzle top is used for supporting with perforation coordinating; Waste product box is for reclaiming suction nozzle.
2. suction nozzle retracting device according to claim 1, is characterized in that, bore a hole as circular hole, suction nozzle top is cylindrical, and the diameter of perforation is less than the diameter on suction nozzle top.
3. adopt the overflow dyeing machine of suction nozzle retracting device described in claim 1 or 2, it is characterized in that, comprise worktable and be all installed on this worktable for the just right scratch diskette of dyeing pin, for the specimen holder just right with sample needle, for the suction nozzle seat just right with sample needle and four-axle linked mechanism, four-axle linked mechanism has the X-axis slipping mechanism along the slippage of worktable X-direction, be installed on X-axis slipping mechanism and along the Y-axis slipping mechanism of worktable Y direction slippage, be installed on Y-axis slipping mechanism and along the slippage of worktable Z-direction Z1 axle slipping mechanism and be installed on Y-axis slipping mechanism and the Z2 axle slipping mechanism be slidably matched along worktable Z-direction, sample needle is installed on Z1 axle slipping mechanism, Z2 axle slipping mechanism is provided with dyeing pin, waste product box is installed on worktable.
4. overflow dyeing machine according to claim 3, it is characterized in that, X-axis slipping mechanism comprises X-axis slide rail and X-axis driving mechanism, Y-axis slipping mechanism comprises Y-axis slide rail and Y-axis driving mechanism, Z1 axle slipping mechanism comprises described Z1 bracing strut and described Z1 axle driving mechanism, and Z2 axle slipping mechanism comprises Z2 bracing strut and Z2 axle driving mechanism, and Y-axis slide rail and X-axis slide rail are slidably matched, Z1 bracing strut and Z2 bracing strut are slidably matched with Y-axis slide rail respectively, and dyeing pin is installed on Z2 bracing strut.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510737105.XA CN105181426A (en) | 2015-10-30 | 2015-10-30 | Recovery device for suction nozzle and dyeing machine |
| PCT/CN2016/091872 WO2017071340A1 (en) | 2015-10-30 | 2016-07-27 | Suction nozzle collection device, and staining machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510737105.XA CN105181426A (en) | 2015-10-30 | 2015-10-30 | Recovery device for suction nozzle and dyeing machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105181426A true CN105181426A (en) | 2015-12-23 |
Family
ID=54903663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510737105.XA Pending CN105181426A (en) | 2015-10-30 | 2015-10-30 | Recovery device for suction nozzle and dyeing machine |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN105181426A (en) |
| WO (1) | WO2017071340A1 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106323712A (en) * | 2016-08-17 | 2017-01-11 | 广州三瑞医疗器械有限公司 | Cell staining slide making machine and staining slide making method |
| WO2017071340A1 (en) * | 2015-10-30 | 2017-05-04 | 广州鸿琪光学仪器科技有限公司 | Suction nozzle collection device, and staining machine |
| CN109297792A (en) * | 2018-10-18 | 2019-02-01 | 广州安必平医药科技股份有限公司 | All-in-one machine is dyed in film-making |
| CN112345784A (en) * | 2020-10-22 | 2021-02-09 | 烟台海深威软件有限公司 | Sample adding needle, needle withdrawing mechanism used for sample adding needle and needle installing and withdrawing method |
| CN116148027A (en) * | 2023-04-18 | 2023-05-23 | 北京层浪生物科技有限公司 | Sample preparation instrument |
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| CN108613860A (en) * | 2018-07-27 | 2018-10-02 | 上海皓信生物科技有限公司 | Liquid-based pelleter |
| CN110849692B (en) * | 2019-12-20 | 2024-03-15 | 广州江元医疗科技有限公司 | Full-automatic film-making dyeing equipment and full-automatic film-making dyeing method |
| CN112345317B (en) * | 2020-09-09 | 2022-09-27 | 安徽九陆生物科技有限公司 | Liquid-based cell slide scanning and reading mechanism and using method thereof |
| CN112255060A (en) * | 2020-10-09 | 2021-01-22 | 嘉兴晶铸生物科技有限公司 | Sealing device and sealing method |
| CN112461631B (en) * | 2020-10-27 | 2022-09-27 | 安徽九陆生物科技有限公司 | Dyeing needle lifting device for liquid-based thin-layer cell sheet-making dyeing machine |
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| CN112345784A (en) * | 2020-10-22 | 2021-02-09 | 烟台海深威软件有限公司 | Sample adding needle, needle withdrawing mechanism used for sample adding needle and needle installing and withdrawing method |
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| Publication number | Publication date |
|---|---|
| WO2017071340A1 (en) | 2017-05-04 |
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Application publication date: 20151223 |