CN105169089A - Traditional Chinese medicine pill for treating headache during menstruation and preparing method of traditional Chinese medicine pill - Google Patents

Traditional Chinese medicine pill for treating headache during menstruation and preparing method of traditional Chinese medicine pill Download PDF

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CN105169089A
CN105169089A CN201510716038.3A CN201510716038A CN105169089A CN 105169089 A CN105169089 A CN 105169089A CN 201510716038 A CN201510716038 A CN 201510716038A CN 105169089 A CN105169089 A CN 105169089A
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radix
fructus
blood
liver
immersion
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赵文彬
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Abstract

The invention discloses a traditional Chinese medicine pill for treating headache during menstruation and a preparing method of the traditional Chinese medicine pill and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine pill is prepared from Huai wheat, codonopsis pilosula, ventilago leiocarpa benth, rehmannia glutinosa, mulberry fruits, Chinese dates, longan aril, polygonum multiflorum, uncaria, eclipta, cortex moutan, glossy privet fruits, fructus corni, manyprickle acanthopanax roots, herba lycopi, leonurus, radix bupleuri, caulis spatholobi, donkey-hide gelatin, corydalis tubers, lumbricus, arisaema cum bile, liquorice and motherwort fruits. The selected medicine materials are compatible and complementary, the pill is applied appropriately according to pathogenesis, the effects of tonifying the liver and the kidney, replenishing qi, eriching the blood, activating collaterals, relieving pains, promoting the blood circulation to remove blood stasis, activating blood to promote menstruation, soothing liver-qi stagnation, clearing away heat, calming the liver, relieving dizziness and spasm, nourishing the heart and soothing the nerves, the absorbing effect is good, the curative effect is remarkable, toxic and side effects and clinical adverse effects do not exist, and it is clinically verified that the cure rate on headache during menstruation is high.

Description

A kind of medicine pill and preparation method being used for the treatment of headache during menstruation
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine pill and the preparation method that are used for the treatment of headache during menstruation.
Background technology
Headache during menstruation, names of disease of tcm, before and after referring to each menstrual period or passing through, occurs having a headache for cardinal symptom, through after disappearance, be called headache during menstruation.Be mainly in the women that passes through.Primary disease belongs to the category of western medicine premenstrual tension syndrome.
Treatment headache during menstruation, modern medicine there is no specific treatment scheme, generally press the disease symptomatic treatments such as nervous headache, when having a headache obvious, can stabilize, the doctor trained in Western medicine analgesic type drug such as rotundine is oral, but these medicines play temporary relief effect mostly, thoroughly can not cure, and there is certain side effect.
The traditional Chinese medical science thinks that headache during menstruation is due to the partially prosperous initiation of deficiency of qi and blood, blood stasis, liver-fire, and deficiency of qi and blood is topmost paathogenic factor.Between women menstrual period, menses run off in a large number and cause deficiency of both QI and blood.Deficiency of both QI and blood causes vim and vigour running not smooth, and blood stasis is then obstructed, stagnation of QI and blood may bring about pain, if can not treat in time, will be converted into periodically or other type comparatively obstinate headache.Medical material selected by pill of the present invention, the property of medicine is suitable mutually auxiliary mutually, suit the remedy to the case for the cause of disease, there is liver and kidney tonifying, vigorate qi and replenish the blood, effect of activating collaterals to relieve pain, blood circulation promoting and blood stasis dispelling, promoting blood circulation to restore menstrual flow, dispersing the stagnated live-QI to relieve the stagnation of QI, heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, tranquilizing by nourishing the heart, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to headache during menstruation cure rate through clinical verification.
Summary of the invention
The invention provides a kind of medicine pill and the preparation method that are used for the treatment of headache during menstruation, there is liver and kidney tonifying, vigorate qi and replenish the blood, effect of activating collaterals to relieve pain, blood circulation promoting and blood stasis dispelling, promoting blood circulation to restore menstrual flow, dispersing the stagnated live-QI to relieve the stagnation of QI, heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, tranquilizing by nourishing the heart, cure the disease and ask source treating both the principal and secondary aspects of a disease, to the headache during menstruation that a variety of causes causes, all there is good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine pill for headache during menstruation, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Be used for the treatment of a preparation method for the medicine pill of headache during menstruation, comprise following processing step:
(1) Huai wheat, Fructus Jujubae, Herba Ecliptae, Cortex Moutan, Fructus Ligustri Lucidi, Fructus Corni, Radix Et Caulis Acanthopanacis Senticosi, Herba Lycopi, Herba Leonuri, Arisaema Cum Bile, Radix Glycyrrhizae, Fructus Leonuri are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Radix Codonopsis, Radix seu Caulis Verntilaginis Leiocarpae, Radix Rehmanniae Preparata, Fructus Mori, Arillus Longan, Radix Polygoni Multiflori, Ramulus Uncariae Cum Uncis, Caulis Spatholobi are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) cleaned by Radix Bupleuri, add quantitative rice vinegar and mix thoroughly, after moistening to vinegar is sucked, puts in parch container, heat fried dry with slow fire, taking-up is dried in the air cool, and sieve removes chip, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(4) Rhizoma Corydalis is put into iron pan, add quantitative yellow wine and mix thoroughly, vexed, slow fire heats, fried dry, and taking-up cools, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(5) Pheretima is cleaned oven dry, taking-up is dried in the air cool, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6), after Colla Corii Asini pulverizing being ground into powder, add appropriate clear water, heat after making Colla Corii Asini dissolve Yu Shuizhong, obtain medicinal liquid, for subsequent use;
(7) by the thick paste of step (1), step (2) gained and the medicinal liquid of step (6) gained, mix with the fine powder of gained in step (3), step (4), step (5), add after refined honey stirs, be prepared as the pill of every 8g.
The property of medicine of the present invention's Chinese medicine used is as follows:
Huai wheat: sweet in the mouth; Property is put down.Enter heart channel.Tranquilizing by nourishing the heart.Cure mainly mind not peaceful; The diseases such as insomnia." Medical Treasures of the Golden Chamber " carries: " control hysteria, can sweating due to debility be held back, and have QI invigorating, nourish heart, heat extraction function, can be used for fever due to yin deficiency, the cards such as hectic fever due to YIN-deficiency consumptive fever." Huai wheat is good at nourishing heart will of allaying excitement, for the disease of the malaise such as abnormal mind and uneasy sleeping at night, often coordinates Radix Glycyrrhizae, the same use of Fructus Jujubae, have tranquilizing by nourishing the heart effect.
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung; Supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach; Anorexia and loose stool; Limbs fatigue; The deficiency of the lung is breathed with cough; To breathe hard spontaneous perspiration; The all cards of deficiency of both QI and blood." moral joins book on Chinese herbal medicine " carries: " lung heat clearing gold, invigorating primordial QI, opens sound, helps biceps." modern medicine study confirms; Radix Codonopsis energy Gastrointestinal motility adjustment, antiulcer, enhancing immunologic function; on excited and suppress two kinds of nervous process to have impact, can raise erythrocyte, hemoglobin, reticulocyte, also have the effect of slow down aging and antioxidation, radioprotective, blood pressure lowering.
Radix seu Caulis Verntilaginis Leiocarpae: sweet in the mouth; Warm in nature.Return lung; Spleen channel.Fill blood; Bone and muscle strengthening; Relax meridians.Cure mainly deficient qi and blood; Have through uncomfortable; Blood deficiency amenorrhea; Rheumatalgia; Traumatic injury; Lumbar muscle strain." conventional Chinese herbal medicine handbook ": rich in nutrition, relaxing muscles and tendons and activating QI and blood in the collateral.Control deficiency of both QI and blood, menoxenia, bones and muscles pain due to rheumatism, numb limbs and tense tendons, traumatic injury.
Radix Rehmanniae Preparata: sweet in the mouth; Warm in nature; Return liver; Kidney channel.Enrich blood moist; Benefit essence fills out marrow.Cure mainly blood tiger sallow; Dizzy cardiopalmus; Hepatic and renal YIN deficiency; Soreness of the waist and knees; To suffer from a deficiency of the kidney dyspnea with rapid and short breath." book on Chinese herbal medicine converges and says " carries: " prolonged illness the moon wound, new product blood loses, the required person of institute also." modern medicine study confirmation, Radix Rehmanniae Preparata can strengthen GSH-Px activity, reduces the content of LPO in serum, improves plasma A D concentration, also has closely-related effect in addition with medulla hematopoietic system.
Fructus Mori: sweet in the mouth; Acid; Cold in nature.Return liver; Kidney channel.Nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Cure mainly having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.
Fructus Jujubae: sweet in the mouth; Temperature.Return spleen; Stomach warp.Tonifying the spleen and stomach; Replenishing QI and blood; Tranquilizing mind; Battalion is adjusted to defend; And the property of medicine.Cure mainly weakness of the spleen and stomach; Insufficiency of vital energy and blood; Anorexia and loose stool; Fatigue and weakness; Palpitation and insomnia; Woman hysteria; Disharmony of nutrient QI with defensive QI." book on Chinese herbal medicine remittance speech ": Shen Shi says, and the sweet profit cream of this medicine coagulates, kind nourishing YIN sun, QI and blood, body fluid, venation, muscle Yu, bone marrow, and all are deficient, without shoulding not it.As imperial Tan Fang controls palpitation with fear palpitation with a distress feeling, dimly forgetful, will meaning stupor, spirit is not kept, or middle gas discord, poor appetite, and hundred body lazynesses are heavy, and muscle is thin, and the card that this belongs to the heart, spleen two hides unit god loss, must control it with Fructus Jujubae.Assistant Pericarpium Citri Reticulatae, adjusts the empty stagnant expectorant of the smooth middle part of gastric cavity.
Arillus Longan: sweet in the mouth; Warm in nature.Enter the heart; Kidney; Liver; Spleen channel.Reinforcing the heart spleen; Replenishing QI and blood; Tranquilizing mind.Cure mainly the palpitation with fear caused by deficiency of both the heart and spleen, insufficiency of vital energy and blood; Palpitation with a distress feeling; Insomnia; Forgetful; Blood deficiency and yellow complexion; Menoxenia; Metrorrhagia." must join book on Chinese herbal medicine " carries: " strengthening the spleen stomach, preserve painstaking effort, moistening five ZANG-organs, controls palpitation with a distress feeling." modern medicine study confirmation, Arillus Longan is stimulated by low temperature, high temperature and anoxia to be had significant protective effect to cardiac muscle, has inhibitory action to Microsporon audouini, also has calm and digestion promoting function in addition.
Radix Polygoni Multiflori: bitter in the mouth; Sweet; Puckery; Slightly warm in nature.Return liver; Kidney channel.Nourishing the blood and yin; Loosening bowel to relieve constipation; Preventing the attack (or recurrence) of malaria; Dispel the wind; Removing toxic substances.Cure mainly: blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body is empty; Rubella pruritus; Carbuncle sore; Scrofula; Hemorrhoid." book on Chinese herbal medicine is just ": the Radix Polygoni Multiflori, specially enters Liver and kidney, take a tonic or nourishing food to build up one's health Kidney-Yin, and taste is admittedly very thick, and slightly hold concurrently pained, property is then gentle, and the reason of all sealing Tibetan with the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels meets, therefore can fill out beneficial vital essence, has negative and positive and puts down secret effect, and non-relatively the moon as Radix Rehmanniae is solidifying comparable.Good Gu meaning eliminating pathogen in the liver wind, be that the moon does not contain sun, water does not support wood, is cause the raw wind of edema with the liver involved, and this energy nourishing YIN, then control wind and first control blood, and blood wind is from going out, and also its institute is suitable.But this nourishes with endogenous wind stopping, must take for eliminating pathogen in the liver.
Ramulus Uncariae Cum Uncis: bitter in the mouth; Bitter; Cold nature.Enter liver; Heart channel.Heat clearing away suppressing the hyperactive liver; Relieving spasm by subduing liver-wind.Cure mainly infantile convulsion; Night cry; Intenseness of heat wind symptom; Eclamposia; Dizziness due to hyperactivity of liver-YANG; Liver-fire distending pain in the head." book on Chinese herbal medicine is stated " carries: " control paralysis due to windstroke, deviation of the eye and mouth, and all brothers' migratory arthralgia caused by wind pain, podomere contraction is anxious.Control again many years ago gout paralysis, spasm of muscles and vessels is had a pain endlessly person." modern medicine study confirmation; the indoles alkaloid that Ramulus Uncariae Cum Uncis includes, except having blood pressure lowering, antiepileptic action, also has certain angst resistance effect; the synapse transmittance process of alcohol extract to central nervous system has obvious depression effect, can strengthen the protection to neuronal cell.
Herba Ecliptae: sweet in the mouth; Acid; Cool in nature.Return liver; Kidney channel.Liver and kidney tonifying; Cooling blood for hemostasis.Cure mainly: deficiency of the liver and kindey; Have a dizzy spell; Early whitening of beard and hair; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Dysentery; Collapse; Leak; Traumatic hemorrhage." classifying herbal ": hemostasis, the kidney invigorating, annealing, detumescence.Control pouring, collapse.
Cortex Moutan: acrid in the mouth; Bitter; Cool in nature; Be slightly cold.Enter the heart; Liver; Kidney; Lung meridian.Heat clearing away; Blood circulation promoting and blood stasis dispelling.Cure mainly the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; Brimful of tears; Virus later stage hot Fu Yin divide heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.Shennong's Herbal carries: " main cold and heat, apoplexy clonic convulsion, convulsion, infantile convulsion pathogen, except the hard blood stasis of disease stays house the intestines and stomach, settling five organs, treat carbuncle skin ulcer.Modern medicine study confirms, Cortex Moutan has the effects such as antipyretic, antiinflammatory, antiallergic action, effectively strengthens the immunologic function of body fluid and cell, has obvious protective effect, have obvious inhibitory action to platelet aggregation to myocardial ischemia.
Fructus Ligustri Lucidi: bitter in the mouth; Cool in nature.Return liver; Kidney channel.Tonifying liver kidney yin, crow must improving eyesight.Cure mainly the hepatic and renal YIN deficiency; Soreness of waist tinnitus; Early whitening of beard and hair; Unseeing; Fever due to yin deficiency; Gastropathy and gout and hyperuricemia." book on Chinese herbal medicine is stated " carries: " Fructus Ligustri Lucidi is real, admittedly enter sea of blood benefit blood, and gentle above flourish ... by kidney to lung, and be skillful in up and down with excessive." modern medicine study proves; Fructus Ligustri Lucidi includes ursolic acid, mannitol, glucose, fatty wet goods multiple element; have heart tonifying, diuresis and hepatoprotective effect, the leukopenia quantity caused because of chemotherapy can be made to raise, and have inhibitory action to staphylococcus aureus, escherichia coli.
Fructus Corni: sour in the mouth; Slightly warm in nature, returns liver; Kidney channel.Liver and kidney tonifying; Convergence is solid de-, cures mainly: waist is had a dizzy spell; Deafness and tinnitus; Soreness of the waist and knees; Xian essence spermatorrhea; Frequent micturition; Incessant sweating due to debility; Woman uterine bleeding." Elementary Medicine ": this astringent of Fructus Corni also, how can lead to and send out heresy? covering all diseases is all bottom deficiency and coldness, the tonic Liver and kidney of use, and with Yi Qiyuan, then the five internal organs Amway, only, the meaning of the light dredging of Fei Ruota medicine also for the logical and sharp person of the person of closing.Modern medicine study shows: Fructus Corni has antibacterial, immunity moderation, blood sugar lowering, blood fat reducing, antioxidation, anticancer, the function such as anti-AIDS, heart tonifying.
Radix Et Caulis Acanthopanacis Senticosi: acrid in the mouth; Micro-hardship; Warm in nature.Return spleen; Kidney; Heart channel.Replenishing kidney, strengthening waist; Benefiting vital QI for tranquillizing; Promoting blood circulation to remove obstruction in the collateral.Main kidney deficiency and bodily weakness; Soreness of the waist and knees; Children's's walking retardation in children; Insufficiency of the spleen weak; Deficiency of vital energy edema; Inappetence; Insomnia and dreamful sleep; Forgetful; Thoracic obstruction pain; Anemofrigid-damp arthralgia; Treating swelling and pain by traumatic injury.Modern medicine study proves that its extract can effective anti-inflammation, has fabulous anti-aging effects.
Herba Lycopi: acrid in the mouth; Micro-hardship; Property micro-wet.Return liver; Spleen channel.Promoting blood circulation to restore menstrual flow; Blood stasis dispelling row water.Cure mainly menoxenia; Dysmenorrhea; Amenorrhea; Puerperal abdonimal pain; WEIJIA; Body and face edema; Carbuncle; Traumatic injury." Chinese herbal medicine is commonly used in Sichuan " carries: " Herba Strobilanthis Japonici, the capable water of repercussive, soothing liver-QI falls apart strongly fragrant." modern medicine study confirms, Herba Strobilanthis Japonici containing volatile oil, tannin, phenols and several amino acids, can prevent thrombosis, have slight anticoagulant system with the effect strengthening fibrinolytic.
Herba Leonuri: acrid in the mouth; Bitter; Property micro-enter.Return liver; Kidney; Pericardium channel.Promoting blood flow to regulate menstruation; Inducing diuresis to remove edema; Heat-clearing and toxic substances removing.Cure mainly menoxenia; Amenorrhea; Vaginal bleeding during pregnancy is had difficult labour; Retention of placenta; Puerperal blood faints; Abdominal pain due to blood stasis; Traumatic injury; Dysuria; Edema; Carbuncle skin infection." book on Chinese herbal medicine is looked for the truth " carries: " disappear water promoting the circulation of blood, removes crazy tissue regeneration promoting, and regulating menstruation is detoxified, for wanting agent after tire front tyre." modern medicine study shows; the leonurines contained by Herba Leonuri etc. have excitation to uterus; antiplatelet aggregation, coagulation; improve coronary circulation, cardioprotection; strengthen cardiac contractile force; direct excited respiratory center, slow intestinal tube tonicity of speeding, and also have the effect such as CNS inhibition, bacteriostatic in addition.
Radix Bupleuri: bitter in the mouth; Pungent; Cold nature.Return liver; Gallbladder meridian.Induce sweat and bring down a fever; Dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure mainly: fever caused by exogenous pathogens; Alternate attack of chill and fever; Malaria; Hypochondriac pain due to stagnation of liverQI mammary swelling; Headache dizziness; Menoxenia; The proctoptosis of collapse of QI; Uterine prolapse; Gastroptosis." detailed outline ": " control yang-energy to sink, suppressing the hyperactive liver, gallbladder, three burnt, envelope is mutually fiery, and headache, dizzy, and blurred vision, swelling pain are hidden from view, deaf ring, all malarias, and lump at the left hypochondrium cold and heat, married woman's invasion of the blood-chamber by heat, irregular menstruation, children's's varioliform exanthema waste heat, the thin heat of five kinds of child malnutrition." modern medicine study confirms, Radix Bupleuri has antipyretic, calm, analgesia, antitussive, antiinflammatory action.Resist hepatic injury, function of gallbladder promoting, anti-fatty liver simultaneously, and promote that enterokinesia etc. has certain effect.
Caulis Spatholobi: bitter in the mouth; Micro-sweet; Warm in nature.GUIXIN; Spleen channel.Relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.Cure mainly numb hand and foot; Quadriplegia; Rheumatic arthralgia." decoction pieces is newly joined " carries: " fluent passages through which vital energy circulates, controls summer filthy infection for blood stasis removing blood, tissue regeneration promoting blood, wind arthralgia due to stagnation of blood disease." modern medicine study confirmation, Caulis Spatholobi has blood tonification effect, can increase hemocyte quantity, raises hemoglobin, has antiphagin effect.
Colla Corii Asini: sweet in the mouth; Property is put down.Enter liver; Lung; Kidney channel.Enrich blood; Hemostasis; YIN nourishing; Moisturize.Cure mainly syndrome of deficiency of blood; Asthenia is spat blood; Spit blood; Hematuria; Have blood in stool; Dysentery; Gestation hemorrhage; Metrorrhagia; The vexed insomnia of the deficiency of YIN; Deficiency of the lung cough caused by dryness; The convulsion of stirring-up of pathogenic wind in the interior resulting from deficiency is fainted tic.Compendium of Material Medica is carried: " all syndrome caused by wind pathogen of men and women, arthralgia, aqueous vapor edema, cough due to consumptive disease dyspnea with rapid respiration, consumptive lung disease spitting bloody pus, and swollen ulcer drug.With blood YIN nourishing, except wind is moisturized, lung heat clearing of reducing phlegm, diuresis, tunes up intestinal." modern medicine study confirmation, Colla Corii Asini has powerful blood tonification effect, and curative effect is better than chalybeate, can regulate creatinine and creatine level, prevents vitamin E Oxidative demage, promotes positive calcium balance, prevents and treats progressive muscular dystrophy, also has raising blood pressure and Antishock function in addition.
Rhizoma Corydalis: acrid in the mouth; Bitter; Warm in nature; Nontoxic.Enter liver; Stomach; The heart; Lung; Spleen channel.Invigorate blood circulation; Dissipating blood stasis; Regulate the flow of vital energy; Pain relieving.Cure mainly all pains of trusted subordinate's waist knee joint; Menoxenia; Lump in the abdomen; Metrorrhagia; Puerperal blood faints; Lochiorrhea; Traumatic injury." detailed outline " carries: " stagnation of QI in energy promoting the circulation of blood, stasis in gas, therefore specially control upper and lower all pains all over the body, among using, simply fantastic.Invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis." modern medicine study shows, Rhizoma Corydalis has significant analgesia, calmness, hypnosis, stable effect, and excited gastrointestinal smooth muscle, significantly expands coronary vasodilator, can cause the secretion of PATH, have relaxation effect to muscle.
Pheretima: salty in the mouth; Cold in nature.Return liver; Spleen; Urinary bladder channel.Clear gesture relieving convulsion; Suppressing the hyperactive liver to relieve the wind syndrome; Dredge the meridian passage; To relieving asthma diuresis.Cure mainly calentura heating mad dry; Infantile convulsion is twitched; Headache due to hyperactivity of liver-YANG; Apoplectic hemiplegia; Rheumatic arthralgia; Dyspnea and cough due to lung-heat; Urinary obstruction.Compendium of Material Medica is carried: " cold in nature and descending, cold in nature therefore can separate all hot diseases, descending former energy diuresis, controls sufficient disease and the meridian dredging also.Main typhoid fever malaria, large fanatical tired, and children's's adult urinary obstruction, anxious chronic infantile convulsion, severe and migratory arthralgia pain." modern medicine study proves, Pheretima contains the compositions such as ground LONGSU, lumbrofebrin, vitamin B complex complex, there is diuresis, ease pain, relieving asthma, blood pressure lowering, the effect such as antipyretic, convulsion.
Arisaema Cum Bile: bitter in the mouth; Micro-pungent; Cool in nature.Enter liver; Gallbladder; Lung meridian.Clearing away fire and eliminating phlegm; Relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Cure mainly apoplexy; Infantile convulsion; Epilepsy; Headache; Dizzy; Breathe heavily and cough." book on Chinese herbal medicine just " carries: " control anxious frightened, Jiao is closed in real expectorant excess-fire heap soil or fertilizer over and around the roots, and asthma is irritated, terribly thirsty distension." clinic study shows, Arisaema Cum Bile has loose wind, eliminates the phlegm, effect of relieving convulsion, pain relieving, and can be used for treatment apoplexy paralysis, carpopedal spasm, has a headache dizzy, the diseases such as infantile convulsion abundant expectoration.
Radix Glycyrrhizae: sweet in the mouth; Property is put down.GUIXIN; Lung; Spleen; Stomach warp.Invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach; Fatigue and weakness; Shortness of breath and palpitation; Cough with copious phlegm; Gastral cavity abdomen four muscle spasm of the leg and foot pain; Carbuncle sore tumefacting virus; Cushion toxicity.Compendium of Material Medica is carried: " in all medicines, Radix Glycyrrhizae is monarch.Control 72 kinds of mammary calculus poison, draft is malicious by every means to separate 1,002, is in harmonious proportion from medicine and gains merit." modern medicine study confirmation; Radix Glycyrrhizae has stronger Detoxication; also have antiulcer, anti-inflammatory, spasmolytic antitussive, blood pressure lowering, blood fat reducing, antitumaous effect; be widely used in the diseases such as treatment pharyngolaryngitis, laryngitis, tracheitis, bronchitis, asthma, cough, hemoptysis, have anti-gastric-ulcer, gastritis effect in addition.
Fructus Leonuri: sweet in the mouth; Pungent; Cold nature; Mild toxicity.Enter Liver Channel.Promoting blood flow to regulate menstruation; Liver heat removing and eyesight improving.Cure mainly menoxenia; Dysmenorrhea; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Liver-heat is had a headache; Dizzy; Conjunctival congestion and swelling pain; The raw cataracta of order." Bencao Jingshu " carries: " large heat headache is vexed, and all the time of blood deficiency and heat also, liver heat removing heat radiation and blood, then vexed all solutions of having a headache." modern medicine study confirmation, Fructus Leonuri, containing leonurinine alkali, stachydrine, fatty oil, 17 seed amino acids and 24 kinds of mineral elements, has slight hypotensive effect, has the effect of inhibition paralysis to central nervous system.
The present invention compared with prior art, has following beneficial effect:
The present invention selects medical material, the property of medicine is suitable mutually auxiliary mutually, suit the remedy to the case for causing the causes of disease such as the deficiency of qi and blood of headache during menstruation, blood stasis, liver-fire is partially prosperous, there are liver and kidney tonifying, vigorate qi and replenish the blood, effect of activating collaterals to relieve pain, blood circulation promoting and blood stasis dispelling, promoting blood circulation to restore menstrual flow, dispersing the stagnated live-QI to relieve the stagnation of QI, heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, tranquilizing by nourishing the heart, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to headache during menstruation cure rate through clinical verification.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The processing step of process for preparing medicine of the present invention is:
(1) Huai wheat, Fructus Jujubae, Herba Ecliptae, Cortex Moutan, Fructus Ligustri Lucidi, Fructus Corni, Radix Et Caulis Acanthopanacis Senticosi, Herba Lycopi, Herba Leonuri, Arisaema Cum Bile, Radix Glycyrrhizae, Fructus Leonuri are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Radix Codonopsis, Radix seu Caulis Verntilaginis Leiocarpae, Radix Rehmanniae Preparata, Fructus Mori, Arillus Longan, Radix Polygoni Multiflori, Ramulus Uncariae Cum Uncis, Caulis Spatholobi are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) cleaned by Radix Bupleuri, add quantitative rice vinegar and mix thoroughly, after moistening to vinegar is sucked, puts in parch container, heat fried dry with slow fire, taking-up is dried in the air cool, and sieve removes chip, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(4) Rhizoma Corydalis is put into iron pan, add quantitative yellow wine and mix thoroughly, vexed, slow fire heats, fried dry, and taking-up cools, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(5) Pheretima is cleaned oven dry, taking-up is dried in the air cool, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6), after Colla Corii Asini pulverizing being ground into powder, add appropriate clear water, heat after making Colla Corii Asini dissolve Yu Shuizhong, obtain medicinal liquid, for subsequent use;
(7) by the thick paste of step (1), step (2) gained and the medicinal liquid of step (6) gained, mix with the fine powder of gained in step (3), step (4), step (5), add after refined honey stirs, be prepared as the pill of every 8g.
Usage and dosage: oral, premenstrual 5 days start to take, every day 3 times, each 2 balls, and one hour ante cibum, with warm water delivery service, 10 days was a course for the treatment of.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection
The routine clinical observation of headache during menstruation patient 40 selecting my institute to make a definite diagnosis, women, 27 ~ 43 years old age, 34.6 years old mean age, the shortest person of the course of disease 3 months, most elder 3 years, average 1.1 years.
2, patient takes medicine of the present invention, oral, and premenstrual 5 days start to take, every day 3 times, each 2 balls, and one hour ante cibum, with warm water delivery service, 10 days was a course for the treatment of.
3, efficacy determination:
(1) cure: headache during menstruation clinical symptom disappearance, aperiodicity is shown effect.
(2) take a turn for the better: headache during menstruation clinical symptoms obviously alleviates, or recur again in rear 3 menstrual cycle of headache disappearance.
(3) invalid: symptom is with treating front no significant difference.
4, result
Headache during menstruation patient cures 27 examples, and take a turn for the better 9 examples, invalid 4 examples, cure rate 67%, total effective rate 90%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, ×× is opened, female, 35 years old, office worker.This patient is over nearly 2 months, and often before menstrual onset or there will be dizziness menstrual period, head has a dull ache, poor sleeping quality, the symptoms such as neurolysis, and Hypomenorrhea, the light matter of color is rare, pale tongue with thin fur, deficient and thready pulse.Be diagnosed as headache during menstruation, through taking medicine of the present invention, oral, premenstrual 5 days start to take, every day 3 times, and each 2 balls, one hour ante cibum, with warm water delivery service, 10 days was a course for the treatment of.After taking 1 course for the treatment of, above-mentioned symptom disappears completely, within latter 3 months, does not recur, fully recovers.
2, what ××, female, 38 years old, teacher.Patient is over 1 year, often before menstrual onset or there will be head distending pain menstrual period, pain as vertebra thorn, sensation of oppression over the chest with shortness of breath, have palpitation, the symptom such as physical fatigue and lassitude of spirit, dark menses has block, and tongue is dim, thready and hesitant pulse.Be diagnosed as headache during menstruation, through taking medicine of the present invention, oral, premenstrual 5 days start to take, every day 3 times, and each 2 balls, one hour ante cibum, with warm water delivery service, 10 days was a course for the treatment of.After taking 1 course for the treatment of, above-mentioned symptom is obviously alleviated, and after continuing to take 1 course for the treatment of, above-mentioned symptom disappears completely, within latter 3 months, does not recur, fully recovers.
Pill of the present invention sums up configuration through Long-term clinical checking to form, selected medical material in side, and the property of medicine is suitable mutually auxiliary mutually, suits the remedy to the case for the cause of disease, and in side, the Chinese medicine such as Herba Ecliptae, Fructus Ligustri Lucidi, Fructus Corni can liver and kidney tonifying; In side, the Chinese medicine such as Radix Codonopsis, Arillus Longan can vigorate qi and replenish the blood; In side, the Chinese medicine such as Colla Corii Asini, Radix Rehmanniae Preparata, Fructus Mori, Radix Polygoni Multiflori can be enriched blood YIN nourishing; In side Radix Bupleuri can induce sweat bring down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI; In side, the Chinese medicine such as Ramulus Uncariae Cum Uncis, Pheretima can heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind; In side, the Chinese medicine such as Herba Lycopi, Radix Et Caulis Acanthopanacis Senticosi, Herba Leonuri, Caulis Spatholobi can promoting blood circulation to restore menstrual flow, removing obstruction in the collateral to relieve pain; In side, the Chinese medicine such as Cortex Moutan, Rhizoma Corydalis can blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain; In side, Huai wheat coordinates Radix Glycyrrhizae, the same use of Fructus Jujubae, has tranquilizing by nourishing the heart effect; In side, Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription; In side, all medicines share and play liver and kidney tonifying, vigorate qi and replenish the blood altogether, effect of activating collaterals to relieve pain, blood circulation promoting and blood stasis dispelling, promoting blood circulation to restore menstrual flow, dispersing the stagnated live-QI to relieve the stagnation of QI, heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind, tranquilizing by nourishing the heart, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to headache during menstruation cure rate through clinical verification.

Claims (4)

1. be used for the treatment of a medicine pill for headache during menstruation, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Huai wheat 66 ~ 80g Radix Codonopsis 63 ~ 76g Radix seu Caulis Verntilaginis Leiocarpae 60 ~ 73g Radix Rehmanniae Preparata 57 ~ 70g
Fructus Mori 54 ~ 67g Fructus Jujubae 51 ~ 63g Arillus Longan 48 ~ 60g Radix Polygoni Multiflori 45 ~ 56g
Ramulus Uncariae Cum Uncis 42 ~ 53g Herba Ecliptae 39 ~ 49g Cortex Moutan 36 ~ 46g Fructus Ligustri Lucidi 33 ~ 43g
Fructus Corni 30 ~ 40g Radix Et Caulis Acanthopanacis Senticosi 27 ~ 37g Herba Lycopi 24 ~ 34g Herba Leonuri 21 ~ 31g
Radix Bupleuri 18 ~ 28g Caulis Spatholobi 15 ~ 25g Colla Corii Asini 12 ~ 22g Rhizoma Corydalis 10 ~ 19g
Pheretima 8 ~ 15g Arisaema Cum Bile 6 ~ 12g Radix Glycyrrhizae 4 ~ 9g Fructus Leonuri 2 ~ 6g.
2. a kind of medicine pill being used for the treatment of headache during menstruation according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Huai wheat 69 ~ 77g Radix Codonopsis 66 ~ 73g Radix seu Caulis Verntilaginis Leiocarpae 63 ~ 70g Radix Rehmanniae Preparata 60 ~ 67g
Fructus Mori 57 ~ 64g Fructus Jujubae 54 ~ 60g Arillus Longan 51 ~ 57g Radix Polygoni Multiflori 48 ~ 53g
Ramulus Uncariae Cum Uncis 45 ~ 50g Herba Ecliptae 42 ~ 46g Cortex Moutan 39 ~ 43g Fructus Ligustri Lucidi 36 ~ 40g
Fructus Corni 33 ~ 37g Radix Et Caulis Acanthopanacis Senticosi 30 ~ 34g Herba Lycopi 27 ~ 31g Herba Leonuri 24 ~ 28g
Radix Bupleuri 21 ~ 25g Caulis Spatholobi 18 ~ 22g Colla Corii Asini 15 ~ 19g Rhizoma Corydalis 13 ~ 16g
Pheretima 10 ~ 14g Arisaema Cum Bile 7 ~ 10g Radix Glycyrrhizae 5 ~ 7g Fructus Leonuri 3 ~ 5g.
3. a kind of medicine pill being used for the treatment of headache during menstruation according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Huai wheat 74g Radix Codonopsis 70g Radix seu Caulis Verntilaginis Leiocarpae 67g Radix Rehmanniae Preparata 64g Fructus Mori 61g Fructus Jujubae 58g
Arillus Longan 54g Radix Polygoni Multiflori 51g Ramulus Uncariae Cum Uncis 48g Herba Ecliptae 44g Cortex Moutan 41g Fructus Ligustri Lucidi 38g
Fructus Corni 35g Radix Et Caulis Acanthopanacis Senticosi 32g Herba Lycopi 29g Herba Leonuri 26g Radix Bupleuri 23g Caulis Spatholobi 20g
Colla Corii Asini 17g Rhizoma Corydalis 14g Pheretima 12g Arisaema Cum Bile 8g Radix Glycyrrhizae 6g Fructus Leonuri 4g.
4. be used for the treatment of a preparation method for the medicine pill of headache during menstruation, it is characterized in that: comprise following processing step:
(1) Huai wheat, Fructus Jujubae, Herba Ecliptae, Cortex Moutan, Fructus Ligustri Lucidi, Fructus Corni, Radix Et Caulis Acanthopanacis Senticosi, Herba Lycopi, Herba Leonuri, Arisaema Cum Bile, Radix Glycyrrhizae, Fructus Leonuri are cleaned, dried rear mix homogeneously, put into container, add the water of 6 ~ 8 times amount in a reservoir, heated and boiled 2 ~ 3 hours, gets immersion after cooling; The water of 4 ~ 6 times amount is added again, heated and boiled 1 ~ 2 hour, immersion after cooling in remaining medicinal residues; Merge twice gained immersion, heating, evaporation and concentration is the thick paste of relative density 1.15 ~ 1.25, for subsequent use;
(2) Radix Codonopsis, Radix seu Caulis Verntilaginis Leiocarpae, Radix Rehmanniae Preparata, Fructus Mori, Arillus Longan, Radix Polygoni Multiflori, Ramulus Uncariae Cum Uncis, Caulis Spatholobi are put into container, add the shao-hsing rice wine of 3 ~ 5 times amount, cool after boiling, continue immersion 3 ~ 5 hours, get immersion; In remaining medicinal residues, add the shao-hsing rice wine of 2 ~ 4 times amount again, put after boiling and dry in the air, continue immersion 2 ~ 4 hours, get immersion; Merge twice gained immersion, add and steam the thick paste that evaporation and concentration is relative density 1.10 ~ 1.20, for subsequent use;
(3) cleaned by Radix Bupleuri, add quantitative rice vinegar and mix thoroughly, after moistening to vinegar is sucked, puts in parch container, heat fried dry with slow fire, taking-up is dried in the air cool, and sieve removes chip, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(4) Rhizoma Corydalis is put into iron pan, add quantitative yellow wine and mix thoroughly, vexed, slow fire heats, fried dry, and taking-up cools, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(5) Pheretima is cleaned oven dry, taking-up is dried in the air cool, and pulverizing is ground into powder, crosses 120 order dusting covers, obtains fine powder, for subsequent use;
(6), after Colla Corii Asini pulverizing being ground into powder, add appropriate clear water, heat after making Colla Corii Asini dissolve Yu Shuizhong, obtain medicinal liquid, for subsequent use;
(7) by the thick paste of step (1), step (2) gained and the medicinal liquid of step (6) gained, mix with the fine powder of gained in step (3), step (4), step (5), add after refined honey stirs, be prepared as the pill of every 8g.
CN201510716038.3A 2015-10-28 2015-10-28 Traditional Chinese medicine pill for treating headache during menstruation and preparing method of traditional Chinese medicine pill Withdrawn CN105169089A (en)

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