CN105168951A - Health care composition - Google Patents
Health care composition Download PDFInfo
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- CN105168951A CN105168951A CN201510433670.7A CN201510433670A CN105168951A CN 105168951 A CN105168951 A CN 105168951A CN 201510433670 A CN201510433670 A CN 201510433670A CN 105168951 A CN105168951 A CN 105168951A
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- herba dendrobii
- health composition
- lycium ruthenicum
- poria
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Abstract
The invention relates to a composition, in particular to a health care composition, which is characterized by mainly being formed by mixing the following ingredients in parts by weight: 20 to 70 parts of maca, 15 to 25 parts of black fruit Chinese wolfberries, 3 to 15 parts of herba dendrobii and 1 to 30 parts of poria cocos. The health care composition has the advantages that all ingredients supplement each other; and the synergistic effects on resisting oxidation, resisting fatigue, improving the immunity, resisting tumor, delaying the human body senescence, lowering the blood pressure, tonifying the spleen and calming the heart are achieved.
Description
Technical field
The present invention relates to compositions, particularly relate to a kind of health composition.
Background technology
Lepidinm meyenii Walp is a kind of plant of Cruciferae separate row Vegetable spp, originates in mountain area, Peru Andean, locals mainly with it as food, also as conventional medicament use, introduce a fine variety in a large number in Yunnan Province at present.Lepidinm meyenii Walp has resisting fatigue, improvement function, improves the several functions such as fertility.By zoopery and human experimentation research, demonstrate it and there is resisting fatigue, improvement function, antioxidation, minimizing prostatic hyperplasia really, improve the effects such as fertility.
Lycium ruthenicum Murr., be the perennial shrub of Lycium section, Lycium ruthenicum Murr. contains 17 seed amino acids, 13 kinds of trace element, and wherein the content of calcium, magnesium, copper, zinc, ferrum is also higher than red Fructus Lycii.It is the most effective natural free radical scavenger that wild Lycium ruthenicum Murr. contains a large amount of anthocyanin elements, and delaying human body cell tissue is old and feeble.Keep younger state, life lengthening.It is medicinal, and health value is far away higher than common red Fructus Lycii.Be described as " soft gold ".Drink with wild Lycium ruthenicum Murr. bubble for a long time, tool obviously protects vision protection effect, prevents and treats diabetes effect preferably in addition.There is obvious resisting fatigue, protect the liver, antitumor, dredging vascellum, blood pressure lowering, protection Cardiovascular System.
Herba Dendrobii, medicinal history is long, and medicinal ingredient is not only abundant but also balanced, can treat multiple illness, is used for treatment chronic pharyngitis, gastroenteropathy, ophthalmic diseases clinically, the treatment of thrombosis, diabetes, arthritis, cancer or auxiliary treatment.Particularly in recent years for eliminating the side effect after cancer radiation, chemotherapy and recovering physical ability, effect is fairly obvious.Defying age, improves immunity, blood circulation promoting and blood stasis dispelling, improves cardio and vascular function, antitumor, treatment digestive system disease, treatment ophthalmic diseases.
Poria is the dry sclerotia of On Polyporaceae Poria Poriacocos (Schw.) Wolf, sweet in the mouth, light, and property is put down.Be mainly used in treatment edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia; There is promoting diuresis to eliminate damp pathogen, spleen invigorating, effect of mind calming.
Current above-mentioned various raw material all has folk prescription or the finished product processed with other raw material compound recipe or patent, and dosage form has tablet, but has no the product and reported in literature that are made up of above four kinds of raw materials.
Summary of the invention
The object of this invention is to provide a kind of health composition, it is characterized in that, be mainly grouped into by the one-tenth of following weight portion: Lepidinm meyenii Walp 20-70 part, Lycium ruthenicum Murr. 15-25 part, Herba Dendrobii 3-15 part, Poria 1-30 part are obtained by mixing.
Further, be grouped into by the one-tenth of following weight portion: Lepidinm meyenii Walp 35-50 part, Lycium ruthenicum Murr. 18-22 part, Herba Dendrobii 6-12 part, Poria 10-30 part are obtained by mixing.
Further, also comprise probiotic bacteria, account for 60-90 part by weight.
Further, also comprise probiotic bacteria, account for 70-80 part by weight.
Further, described compositions also comprises inulin, starch, oligomeric xylose or cellulose.
Further, described compositions may be used for preparing electuary, capsule, oral liquid or tablet.
Compositions of the present invention is that the functional characteristics respectively had according to Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Cistanches, Poria carries out matched combined, and Lepidinm meyenii Walp has resisting fatigue, improvement function, antioxidation, minimizing prostatic hyperplasia, improves the effects such as fertility; Lycium ruthenicum Murr. has delaying human body cell ageing, has obvious resisting fatigue, protects the liver, antitumor, dredging vascellum, blood pressure lowering, protection Cardiovascular System; Herba Cistanches has effect for the treatment of chills and pain of the waist and kness, woman infertility, neurasthenia, auditory dysesthesia, also has the effect reduced blood pressure; Poria has promoting diuresis to eliminate damp pathogen, spleen invigorating, effect of mind calming, and four supplement and complement each other, and has synergism for antioxidation, resisting fatigue, raising immunity, antitumor, delaying human body caducity, blood pressure lowering, spleen invigorating, mind calming.
Detailed description of the invention
Technical scheme of the present invention is described in detail below in conjunction with embodiment.
Embodiment 1:
Health composition, comprises Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria, the weight of each component: Lepidinm meyenii Walp 70 parts, Lycium ruthenicum Murr. 15 parts, Herba Dendrobii 3 parts, 1 part, Poria are obtained by mixing.Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria can be all crude drug or the compositions for extract.Described extract extracts by the method for prior art with crude drug and obtains.
Embodiment 2:
Health composition, comprises Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria, the weight of each component: Lepidinm meyenii Walp 20 parts, Lycium ruthenicum Murr. 25 parts, Herba Dendrobii 15 parts, Bulbus Lilii 30 parts are obtained by mixing.All the other conditions are identical with embodiment 1.
Embodiment 3:
Health composition, comprises Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria, the weight of each component: Lepidinm meyenii Walp 50 parts, Lycium ruthenicum Murr. 22 parts, Herba Dendrobii 6 parts, 10 parts, Poria.All the other conditions are identical with embodiment 1.
Embodiment 4:
Health composition, comprises Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria, the weight of each component: Lepidinm meyenii Walp 35 parts, Lycium ruthenicum Murr. 22 parts, Herba Dendrobii 12 parts, 20 parts, Poria.All the other conditions are identical with embodiment 1.
Embodiment 5:
Health composition, comprises Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria, probiotic bacteria, the weight of each component: Lepidinm meyenii Walp 35 parts, Lycium ruthenicum Murr. 22 parts, Herba Dendrobii 7 parts, 10 parts, Poria, probiotic bacteria 60 parts.All the other conditions are identical with embodiment 1.
Embodiment 6:
Health composition, comprises Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria, probiotic bacteria, the weight of each component: Lepidinm meyenii Walp 35 parts, Lycium ruthenicum Murr. 22 parts, Herba Dendrobii 7 parts, 30 parts, Poria, probiotic bacteria 90 parts.All the other conditions are identical with embodiment 1.
Embodiment 7:
Health composition, comprises Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria, probiotic bacteria, the weight of each component: Lepidinm meyenii Walp 35 parts, Lycium ruthenicum Murr. 22 parts, Herba Dendrobii 7 parts, 10 parts, Poria, probiotic bacteria 70 parts.All the other conditions are identical with embodiment 1.
Embodiment 8:
Health composition, comprises Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria, probiotic bacteria, the weight of each component: Lepidinm meyenii Walp 35 parts, Lycium ruthenicum Murr. 22 parts, Herba Dendrobii 7 parts, 30 parts, Poria, probiotic bacteria 80 parts.All the other conditions are identical with embodiment 1.
Below the Application Example of said composition, when compositions be crude drug or solid extract time, first pulverize, cross after 50 mesh sieves and prepare burden again.
Embodiment 9:
The preparation of health composition tablet: Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii and Tuckahoe composition 80%, starch 5%, cellulose 15% drop into mixing 10-30 minute in mixer, add ethanol as wetting agent, mixing 10-30 minute, mixed material 12-20 mesh sieve is granulated, and puts into drying equipment inner drying, adds 1% magnesium stearate (or in prior art conventional amount used) of dried particles total amount, granulate, tabletting, packaging, namely makes tablet of the present invention.
Embodiment 10:
The preparation of health composition tablet: Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii, Poria and Herba Leonuri bacteria composition 70%, starch 10%, cellulose 20%, following steps are with embodiment 9.
Embodiment 11:
The preparation of health care composition capsule: Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii and Tuckahoe composition 50%, starch 50%, drops into mixing 10-30 minute in mixer, adds ethanol as wetting agent, mixing 5-10 minute, mixed material 12-20 mesh sieve is granulated, and puts into drying equipment inner drying, adds 1% magnesium stearate (or in prior art conventional amount used) of dried particles total amount, granulate, capsule charge, packaging, namely making content is heavily the capsule of 0.3g.
The additive of above-mentioned health composition is starch, as being preferably one or more combination thing in inulin, oligomeric xylose or cellulose.
Embodiment 12:
The preparation of electuary: Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii and Tuckahoe composition 10%, add 80% dextrin, 10% white sugar, (compositions and white sugar are pulverized, crossed 80 mesh sieves), drops into mixing 10-30 minute in mixer, adds ethanol as wetting agent, mixing 5-10 minute, mixed material 12-20 mesh sieve is granulated, and puts into drying equipment inner drying, dry with the screening of 10-60 eye mesh screen, pack after removing coarse granule and fine powder, be packaged into every bag of 3g.
Embodiment 13:
The preparation of oral liquid: Lepidinm meyenii Walp, Lycium ruthenicum Murr., Herba Dendrobii and Tuckahoe composition, add 5 times amount purified water and obtain oral liquid, add the potassium sorbate (or in prior art conventional amount used) of oral liquid measure 0.1%, filtration, subpackage, sterilizing, packaging, obtain oral liquid of the present invention.
In sum, described health composition can be used for preparing tablet, capsule, electuary, oral liquid.
Embodiment 14:
Experimental conditions is as follows:
(1) health composition (embodiment 4) impact on mice muscle power:
Only choose Male Kunming strain mice 20-24g40, be divided at random 4 groups (often organizing 10 mices), wherein establish normal saline negative control group and 3 health composition various dose groups of the present invention, little, in, the extract of large three dosage component gavage health compositions other every day, dosage is respectively 0.5g/kg, 1.0g/kg, 1.5g/kg, successive administration 40d, carries out mice heavy burden test after last gavage 30min.Mouse tail is born a heavy burden 5%, is placed in 100cm × 80cm × 40cm pond went swimming, depth of water 30cm, water temperature 25 DEG C ± 0.5 DEG C, 10, every pond mice, record mice swimming beginning is the mice burden swimming time to the death time.Experiment shows, 1.0g/kg, 1.5g/kg group can obviously extend the mice burden swimming time, compares have significance (P < 0.01) with negative group.The results are shown in Table 1.
Table 1 physical exertion is tested
Group | Dosage (g/Kg) | Swimming time (S) |
Negative control group | Normal saline | 320.5±126.4 |
Small dose group | 0.5 | 384.3±182.6 |
Middle dosage group | 1.0 | 596.6±231.4 |
Heavy dose of group | 1.5 | 647.5±287.3 |
(2) health composition group (embodiment 13) antitumor performance test:
Zoopery:
5 week age Female nude mice, SPF environment raise, first get 5 nude mices, right side omoplate subcutaneous injection SW1990 cell 1 × 10
7/ only, after 3 weeks, tumor growth is to ~ 500mm
3, conventional treatment nude mice, gets tumor block, chooses eugonic two tumor blocks, is cut into the square fragment of 1mm × 1mm × 1mm, implants other 20 nude mices. and when nude mice lotus tumor grows to ~ 200mm
3during size (2 weeks), be divided into health composition group (n=10) and matched group (n=10) at random;
Carry out pharmaceutical intervention: (1) matched group: lumbar injection and health composition group equal-volume normal saline;
(2) health composition group: 10nmol/g health composition group, lumbar injection, the next day once; Within every three days, measure gross tumor volume by following formula,
Gross tumor volume computing formula: V=(L × W
2) × 0.5;
In formula, L is tumor major diameter, and W is tumor minor axis.
After nude mice treats three weeks, all processed routinely at the 22nd day, take out tumor block, take pictures, retain tumor tissues.
According to the gross tumor volume measurement result of the 21st day, compared with matched group, result shows, and health product are 29.9% (P=0.007) to the suppression ratio of tumor growth.In medication process, medicine shows becomes thin, the untoward reaction that diarrhoea and hemafecia etc. are certain.
Claims (6)
1. a health composition, is characterized in that, is mainly grouped into by the one-tenth of following weight portion: Lepidinm meyenii Walp 20-70 part, Lycium ruthenicum Murr. 15-25 part, Herba Dendrobii 3-15 part, Poria 1-30 part are obtained by mixing.
2. health composition according to claim 1, is characterized in that, is to be grouped into by the one-tenth of following weight portion: Lepidinm meyenii Walp 35-50 part, Lycium ruthenicum Murr. 18-22 part, Herba Dendrobii 6-12, Poria 10-30 part are obtained by mixing.
3. health composition according to claim 1, is characterized in that, also comprises probiotic bacteria, accounts for 60-90 part by weight.
4. health composition according to claim 1, is characterized in that, also comprises probiotic bacteria, accounts for 70-80 part by weight.
5. the health composition according to claim 1 or 3, is characterized in that, also comprises inulin, starch, oligomeric xylose or cellulose.
6. the health composition according to claim 1 or 2 or 3 or 4, is characterized in that: described compound may be used for preparing electuary, capsule, oral liquid or tablet.
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CN201510433670.7A CN105168951A (en) | 2015-07-23 | 2015-07-23 | Health care composition |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107582829A (en) * | 2017-09-21 | 2018-01-16 | 珠海霍普金斯医药研究院股份有限公司 | A kind of functional food of cancer-resisting |
-
2015
- 2015-07-23 CN CN201510433670.7A patent/CN105168951A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107582829A (en) * | 2017-09-21 | 2018-01-16 | 珠海霍普金斯医药研究院股份有限公司 | A kind of functional food of cancer-resisting |
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Application publication date: 20151223 |