CN105168317A - Preparation method and application of astragalus membranaceus extract - Google Patents
Preparation method and application of astragalus membranaceus extract Download PDFInfo
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- CN105168317A CN105168317A CN201510663749.9A CN201510663749A CN105168317A CN 105168317 A CN105168317 A CN 105168317A CN 201510663749 A CN201510663749 A CN 201510663749A CN 105168317 A CN105168317 A CN 105168317A
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Abstract
The invention provides a preparation method and application of an astragalus membranaceus extract. The preparation method specifically comprises the following steps that 1, astragalus membranaceus and 20-25 times of 80% ethyl alcohol by volume are taken, the pH value is regulated to 4-5, the extracting temperature is set at 40 DEG C to 44 DEG C, the extracting time is set to be 5-8 hours, filtering is performed to obtain filter residues, filtrate passes through D-101 macroporous resin at the speed of 0.8-1.2 ml/min for standby application, the ethyl alcohol is recycled and concentrated, part of the ethyl alcohol is eluted, and solvent is recycled through pressure reduction of eluate; 2, the step 1 is repeatedly performed; 3, the filtrate in the step 1 and filtrate in the step 2 are taken to be mixed, the pH value is regulated to 7, pressure reduction concentration is performed, the pressure is set at minus 0.09MPa-minus 0.12MPa, the mixed filtrate is concentrated into extractum with the relative density of 1.6-1.8 (at 25 DEG C-30 DEG C), and then the astragalus membranaceus extract is obtained, wherein the astragalus membranaceus extract contains, by mass, 8%-0.85% of calycosin, 0.6%-0.7% of formononetin and 40%-45% of total saponins of astragalus membranaceus.
Description
Technical field
The present invention relates to agricultural technology field, be specifically related to a kind of preparation method of Radix Astragali extract and the application of extract.
Background technology
The Radix Astragali, has another name called Radix Astragali, and be the general designation of plant and Chinese crude drug, the Radix Astragali is conventional Chinese medicine.The plant Radix Astragali originates in the ground such as the Inner Mongol, Shanxi, Gansu, Heilungkiang, is state three level protecting plant.The Chinese crude drug Radix Astragali is the root of leguminous herbaceous plant's Radix Astagali, Radix Astragali, there is the effects such as invigorating QI to consolidate the body surface resistance, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting, Baidu's experience: the jingyan.baidu.com Radix Astragali is containing the various trace elements such as Saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper.
Former plant is that pulse family herbaceos perennial Radix Astagali and Radix Astragali are all used as medicine with the root of drying.There is the effect such as invigorating QI to consolidate the body surface resistance, diuresis holder skin ulcer, cure mainly the diseases such as exterior deficiency spontaneous perspiration, proctoptosis, uterine prolapse, chronic nephritis.Radix Astagali plant height 40 ~ 80 centimetres.Main root is profound, diameter 1 ~ 3.5 centimetre, cylindrical, sometimes has branch.Surface light brown yellow or light brown.Stem is upright or partly upright, top multi-branched.Leaf alternate, odd number winglike compound leaf, lobule 12 ~ 18 is right, and blade is little, ovalize or Long Circle, and Quan Yuan, below by hair.Stipule lanceolar.Raceme axil is raw, spends 5 ~ 15.Corolla butterfly, yellow to faint yellow, calyx mitriform, close by pubescence, 5 shallowly split, 10 pieces, stamen.5 ~ July of florescence.Pod film quality, expansion, half oval, Glabrous, includes 5 ~ 10, seed.Seed kidney shape, pitchy or sepia.Fruit phase 7 ~ JIUYUE.The difference of Radix Astragali is that lobule quantity is few, and 6 ~ 13 is right, and blade is larger, the blunt circle of tip or nick, sometimes has a stimuli, and stipule is avette linear to draping over one's shoulders needle-like, and pod is by black or chequered with black and white short FUMAO.Between the how wild dry hillside fields on grassland of the Radix Astragali or sparse woods, the nice and cool weather of happiness, cold-resistant drought-enduring, To Be Protected from Heat is afraid of flood.Deep at soil layer, be rich in well-grown on the strong sandy loam of humus, permeable power.Should not plant at clay and strong salt-soda soil.Avoid continuous cropping, should not with the crop rotations such as Flos Carthami, Rhizoma Solani tuber osi, the Rhizoma Atractylodis Macrocephalae, Flos Chrysanthemi.Astragalus membranaceus seed has strong property, and generally, hard seed rate can reach more than 40% ~ 80%.Live only growth stem and leaf and not blooming then, Second Year just can blossom and bear fruit, and within 3 years, blossoms and bears fruit in a large number later.Main product in the Inner Mongol, Shanxi, Heilungkiang, Jilin, Ningxia, the ground such as Gansu, Shandong, Hebei also can be cultivated.One of Astragalus bulk medicinal materials, annual export volume and interior sales volume are all very large, although price fluctuates to some extent, all in all, market demand is increasing, and calculate by existing valency per kilogram 10-12 unit, 2500-3000 unit can be taken in every mu of ground.Astragalus cultivation area reduced in recent years always, and price will also have uptrend the bright year after next.
Summary of the invention
For above-mentioned deficiency of the prior art, the application provides a kind of preparation method of Radix Astragali extract and the application of extract, and concrete scheme is as follows:
A kind of preparation method of Radix Astragali extract comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 20-25 times of volume, adjust ph is 4-5, and Extracting temperature is, 40 ~ 44 ° of C, extract 5-8 hour, filter, obtain filtering residue, filtrate passes through D-101 macroporous resin with 0.8-1.2ml/min speed again, for subsequent use, reclaims ethanol and concentrates; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 20-25 times of volume, adjust ph is 4-5, and Extracting temperature is, 40 ~ 44 ° of C, extract 5-8 hour, filter, obtain filtering residue, filtrate passes through D-101 macroporous resin with 0.8-1.2ml/min speed again, for subsequent use, reclaims ethanol and concentrates; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.09MPa ~-0.12MPa, is concentrated into the extractum that relative density is 1.6 ~ 1.8 (25 ~ 30 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 8% ~ 0.85% respectively mutually, and 0.6% ~ 0.7%, 40% ~ 45%.
Described method comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 20 times of volumes, adjust ph is 4, and Extracting temperature is, 40 ° of C, extracts 5 hours, filters, obtains filtering residue, filtrate again with 0.8ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 20 times of volumes, adjust ph is 4, and Extracting temperature is, 40 ° of C, extracts 5 hours, filters, obtains filtering residue, filtrate again with 0.8ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.09MPa, is concentrated into the extractum that relative density is 1.6 (25 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 8%% respectively mutually, and 0.6%%, 40%%.
Described method comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 25 times of volumes, adjust ph is 5, and Extracting temperature is, 44 ° of C, extracts 8 hours, filters, obtains filtering residue, filtrate again with 1.2ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 25 times of volumes, adjust ph is 5, and Extracting temperature is, 44 ° of C, extracts 8 hours, filters, obtains filtering residue, filtrate again with 1.2ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.12MPa, is concentrated into the extractum that relative density is 1.8 (30 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 0.85% respectively mutually, and 0.7%, 45%.
A kind of application of described Radix Astragali extract, described Radix Astragali extract is for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 10-30 part, lubricant 30-40 part, diluent 15-20 part, Radix Notoginseng 1-5 part, Ganoderma 1-5 part, vitamin e1-5 parts, sweeting agent 1-5 part, correctives 1-5 part; Flavoring orange essence 1-5 part;
Wherein, described diluent refers to one or more of mannitol, sorbitol, lactose, starch, Icing Sugar, sucrosedextrin copolymer;
Described sweeting agent has one or more in stevioside, glycyrrhizin, glucide;
Correctives has one or more in flavoring orange essence, Fructus Citri Limoniae essence, Oleum Menthae Rotundifoliae, Mint Essence, comminution by gas stream spice, chocolate essence;
Lubricant refers to one or more in magnesium stearate, Pulvis Talci, micropowder silica gel.
Described Radix Astragali extract for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 10 parts, lubricant 30 parts, diluent 15 parts, Radix Notoginseng 1 part, Ganoderma 1 part, vitamin e1 part, sweeting agent 1 part, correctives 1 part; Flavoring orange essence 1 part;
Wherein, described diluent refers to mannitol;
Described sweeting agent is glycyrrhizin;
Correctives is flavoring orange essence;
Lubricant refers to Pulvis Talci.
Described Radix Astragali extract for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 30 parts, lubricant 40 parts, diluent 20 parts, Radix Notoginseng 5 parts, Ganoderma 5 parts, vitamin E 5 parts, sweeting agent 5 parts, correctives 5 parts; Flavoring orange essence 5 parts;
Wherein, described diluent refers to sucrosedextrin copolymer;
Described sweeting agent glycyrrhizin;
Correctives Oleum Menthae Rotundifoliae;
Lubricant refers to micropowder silica gel.
Described Radix Astragali extract for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 15 parts, lubricant 35 parts, diluent 18 parts, Radix Notoginseng 2 parts, Ganoderma 3 parts, vitamin E 3 parts, sweeting agent 4 parts, correctives 3 parts; Flavoring orange essence 4 parts;
Wherein, described diluent refers to the mixture of sorbitol, newborn sugar and starch;
Described sweeting agent has stevioside and glucide;
Correctives has flavoring orange essence, Fructus Citri Limoniae essence and Oleum Menthae Rotundifoliae;
Lubricant refers to magnesium stearate, Pulvis Talci and micropowder silica gel.
Detailed description of the invention
embodiment 1
A kind of preparation method of Radix Astragali extract comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 20-25 times of volume, adjust ph is 4-5, and Extracting temperature is, 40 ~ 44 ° of C, extract 5-8 hour, filter, obtain filtering residue, filtrate passes through D-101 macroporous resin with 0.8-1.2ml/min speed again, for subsequent use, reclaims ethanol and concentrates; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 20-25 times of volume, adjust ph is 4-5, and Extracting temperature is, 40 ~ 44 ° of C, extract 5-8 hour, filter, obtain filtering residue, filtrate passes through D-101 macroporous resin with 0.8-1.2ml/min speed again, for subsequent use, reclaims ethanol and concentrates; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.09MPa ~-0.12MPa, is concentrated into the extractum that relative density is 1.6 ~ 1.8 (25 ~ 30 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 8% ~ 0.85% respectively mutually, and 0.6% ~ 0.7%, 40% ~ 45%.
embodiment 2
Described method comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 20 times of volumes, adjust ph is 4, and Extracting temperature is, 40 ° of C, extracts 5 hours, filters, obtains filtering residue, filtrate again with 0.8ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 20 times of volumes, adjust ph is 4, and Extracting temperature is, 40 ° of C, extracts 5 hours, filters, obtains filtering residue, filtrate again with 0.8ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.09MPa, is concentrated into the extractum that relative density is 1.6 (25 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 8%% respectively mutually, and 0.6%%, 40%%.
embodiment 3
Described method comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 25 times of volumes, adjust ph is 5, and Extracting temperature is, 44 ° of C, extracts 8 hours, filters, obtains filtering residue, filtrate again with 1.2ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 25 times of volumes, adjust ph is 5, and Extracting temperature is, 44 ° of C, extracts 8 hours, filters, obtains filtering residue, filtrate again with 1.2ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.12MPa, is concentrated into the extractum that relative density is 1.8 (30 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 0.85% respectively mutually, and 0.7%, 45%.
embodiment 4
A kind of application of described Radix Astragali extract, described Radix Astragali extract is for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 10-30 part, lubricant 30-40 part, diluent 15-20 part, Radix Notoginseng 1-5 part, Ganoderma 1-5 part, vitamin e1-5 parts, sweeting agent 1-5 part, correctives 1-5 part; Flavoring orange essence 1-5 part;
Wherein, described diluent refers to one or more of mannitol, sorbitol, lactose, starch, Icing Sugar, sucrosedextrin copolymer;
Described sweeting agent has one or more in stevioside, glycyrrhizin, glucide;
Correctives has one or more in flavoring orange essence, Fructus Citri Limoniae essence, Oleum Menthae Rotundifoliae, Mint Essence, comminution by gas stream spice, chocolate essence;
Lubricant refers to one or more in magnesium stearate, Pulvis Talci, micropowder silica gel.
embodiment 5
Described Radix Astragali extract for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 10 parts, lubricant 30 parts, diluent 15 parts, Radix Notoginseng 1 part, Ganoderma 1 part, vitamin e1 part, sweeting agent 1 part, correctives 1 part; Flavoring orange essence 1 part;
Wherein, described diluent refers to mannitol;
Described sweeting agent is glycyrrhizin;
Correctives is flavoring orange essence;
Lubricant refers to Pulvis Talci.
Embodiment 6
Described Radix Astragali extract for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 30 parts, lubricant 40 parts, diluent 20 parts, Radix Notoginseng 5 parts, Ganoderma 5 parts, vitamin E 5 parts, sweeting agent 5 parts, correctives 5 parts; Flavoring orange essence 5 parts;
Wherein, described diluent refers to sucrosedextrin copolymer;
Described sweeting agent glycyrrhizin;
Correctives Oleum Menthae Rotundifoliae;
Lubricant refers to micropowder silica gel.
embodiment 7
Described Radix Astragali extract for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 15 parts, lubricant 35 parts, diluent 18 parts, Radix Notoginseng 2 parts, Ganoderma 3 parts, vitamin E 3 parts, sweeting agent 4 parts, correctives 3 parts; Flavoring orange essence 4 parts;
Wherein, described diluent refers to the mixture of sorbitol, newborn sugar and starch;
Described sweeting agent has stevioside and glucide;
Correctives has flavoring orange essence, Fructus Citri Limoniae essence and Oleum Menthae Rotundifoliae;
Lubricant refers to magnesium stearate, Pulvis Talci and micropowder silica gel.
Last it is noted that obviously, above-described embodiment is only for example of the present invention is clearly described, and the restriction not to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without the need to also giving all embodiments.And thus the apparent change of amplifying out or variation be still among protection scope of the present invention.
Claims (7)
1. a preparation method for Radix Astragali extract, is characterized in that, described method comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 20-25 times of volume, adjust ph is 4-5, and Extracting temperature is, 40 ~ 44 ° of C, extract 5-8 hour, filter, obtain filtering residue, filtrate passes through D-101 macroporous resin with 0.8-1.2ml/min speed again, for subsequent use, reclaims ethanol and concentrates; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 20-25 times of volume, adjust ph is 4-5, and Extracting temperature is, 40 ~ 44 ° of C, extract 5-8 hour, filter, obtain filtering residue, filtrate passes through D-101 macroporous resin with 0.8-1.2ml/min speed again, for subsequent use, reclaims ethanol and concentrates; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.09MPa ~-0.12MPa, is concentrated into the extractum that relative density is 1.6 ~ 1.8 (25 ~ 30 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 8% ~ 0.85% respectively mutually, and 0.6% ~ 0.7%, 40% ~ 45%.
2. preparation method according to claim 1, is characterized in that, described method comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 20 times of volumes, adjust ph is 4, and Extracting temperature is, 40 ° of C, extracts 5 hours, filters, obtains filtering residue, filtrate again with 0.8ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 20 times of volumes, adjust ph is 4, and Extracting temperature is, 40 ° of C, extracts 5 hours, filters, obtains filtering residue, filtrate again with 0.8ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.09MPa, is concentrated into the extractum that relative density is 1.6 (25 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 8%% respectively mutually, and 0.6%%, 40%%.
3. preparation method according to claim 1, is characterized in that, described method comprises the steps:
Step one, get Milkvetch Root, 80% ethanol of 25 times of volumes, adjust ph is 5, and Extracting temperature is, 44 ° of C, extracts 8 hours, filters, obtains filtering residue, filtrate again with 1.2ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 2, get the filtering residue of step one, add 80% ethanol of 25 times of volumes, adjust ph is 5, and Extracting temperature is, 44 ° of C, extracts 8 hours, filters, obtains filtering residue, filtrate again with 1.2ml/min speed by D-101 macroporous resin, for subsequent use, reclaim ethanol and concentrated; Ethanol elution part, eluent decompression and solvent recovery;
Step 3, the filtrate of getting step one mix with step 2 filtrate, adjust pH to 7, concentrating under reduced pressure, pressure is-0.12MPa, is concentrated into the extractum that relative density is 1.8 (30 ° of C), obtains Radix Astragali extract, described Radix Astragali extract contains calycosin, formononetin and Radix Astragali total saponins, mass percent should be 0.85% respectively mutually, and 0.7%, 45%.
4. the application of Radix Astragali extract described in a claim 1, it is characterized in that: described Radix Astragali extract is for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 10-30 part, lubricant 30-40 part, diluent 15-20 part, Radix Notoginseng 1-5 part, Ganoderma 1-5 part, vitamin e1-5 parts, sweeting agent 1-5 part, correctives 1-5 part; Flavoring orange essence 1-5 part;
Wherein, described diluent refers to one or more of mannitol, sorbitol, lactose, starch, Icing Sugar, sucrosedextrin copolymer;
Described sweeting agent has one or more in stevioside, glycyrrhizin, glucide;
Correctives has one or more in flavoring orange essence, Fructus Citri Limoniae essence, Oleum Menthae Rotundifoliae, Mint Essence, comminution by gas stream spice, chocolate essence;
Lubricant refers to one or more in magnesium stearate, Pulvis Talci, micropowder silica gel.
5. the application of Radix Astragali extract according to claim 4, it is characterized in that: described Radix Astragali extract is for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 10 parts, lubricant 30 parts, diluent 15 parts, Radix Notoginseng 1 part, Ganoderma 1 part, vitamin e1 part, sweeting agent 1 part, correctives 1 part; Flavoring orange essence 1 part;
Wherein, described diluent refers to mannitol;
Described sweeting agent is glycyrrhizin;
Correctives is flavoring orange essence;
Lubricant refers to Pulvis Talci.
6. the application of Radix Astragali extract according to claim 4, it is characterized in that: described Radix Astragali extract is for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 30 parts, lubricant 40 parts, diluent 20 parts, Radix Notoginseng 5 parts, Ganoderma 5 parts, vitamin E 5 parts, sweeting agent 5 parts, correctives 5 parts; Flavoring orange essence 5 parts;
Wherein, described diluent refers to sucrosedextrin copolymer;
Described sweeting agent glycyrrhizin;
Correctives Oleum Menthae Rotundifoliae;
Lubricant refers to micropowder silica gel.
7. the application of Radix Astragali extract according to claim 4, it is characterized in that: described Radix Astragali extract is for the preparation of the compositions of the Radix Astragali, described Milkvetch root composition by weight, Radix Astragali extract 15 parts, lubricant 35 parts, diluent 18 parts, Radix Notoginseng 2 parts, Ganoderma 3 parts, vitamin E 3 parts, sweeting agent 4 parts, correctives 3 parts; Flavoring orange essence 4 parts;
Wherein, described diluent refers to the mixture of sorbitol, newborn sugar and starch;
Described sweeting agent has stevioside and glucide;
Correctives has flavoring orange essence, Fructus Citri Limoniae essence and Oleum Menthae Rotundifoliae;
Lubricant refers to magnesium stearate, Pulvis Talci and micropowder silica gel.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108030915A (en) * | 2017-12-20 | 2018-05-15 | 阮小军 | Natto kinase composition with anti thrombotic action |
| CN112741237A (en) * | 2021-01-21 | 2021-05-04 | 甘肃陇萃堂营养保健食品股份有限公司 | Concentrated fruit juice capable of keeping stable content of astragaloside and preparation method thereof |
| CN116621344A (en) * | 2023-05-26 | 2023-08-22 | 海南珊海海洋科技有限公司 | Regulator for regulating coral culture water body and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641326A (en) * | 2012-05-17 | 2012-08-22 | 中南大学 | Membranous milkvetch root extract, as well as preparation and application methods thereof |
| CN104784248A (en) * | 2015-04-21 | 2015-07-22 | 四川国康药业有限公司 | Astragalus membranaceus extract, astragalus membranaceus tablet and preparation method thereof |
-
2015
- 2015-10-15 CN CN201510663749.9A patent/CN105168317A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641326A (en) * | 2012-05-17 | 2012-08-22 | 中南大学 | Membranous milkvetch root extract, as well as preparation and application methods thereof |
| CN104784248A (en) * | 2015-04-21 | 2015-07-22 | 四川国康药业有限公司 | Astragalus membranaceus extract, astragalus membranaceus tablet and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108030915A (en) * | 2017-12-20 | 2018-05-15 | 阮小军 | Natto kinase composition with anti thrombotic action |
| CN112741237A (en) * | 2021-01-21 | 2021-05-04 | 甘肃陇萃堂营养保健食品股份有限公司 | Concentrated fruit juice capable of keeping stable content of astragaloside and preparation method thereof |
| CN116621344A (en) * | 2023-05-26 | 2023-08-22 | 海南珊海海洋科技有限公司 | Regulator for regulating coral culture water body and preparation method thereof |
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Application publication date: 20151223 |