CN105125895A - Oral administration medicine capable of treating alopecia areata and preparing method thereof - Google Patents

Abstract

The invention relates to oral administration medicine capable of treating alopecia areata and a preparing method thereof. The medicine is prepared from, by mass, 1-3 parts of radix rehmanniae, 1-3 parts of prepared radix rehmanniae, 1-3 parts of mulberry fruit, 1-3 parts of caulis spatholobi, 1-3 parts of caulis polygoni multiflori, 1-3 parts of raw radix astragalis, 1-3 parts of ligusticum wallichii, 1-3 parts of radix paeoniae alba, 1-3 parts of tall gastrodiae tuber, 1-3 parts of cordyceps sinensis, 1-3 parts of eclipta alba and 1-3 parts of pawpaws. The preparing method of the medicine includes the steps that the high-quality clean first-grade radix rehmanniae, prepared radix rehmanniae, mulberry fruit, caulis spatholobi, caulis polygoni multiflori, raw radix astragalis, ligusticum wallichii, radix paeoniae alba, tall gastrodiae tuber, cordyceps sinensis, eclipta alba and pawpaws are selectively purchased by mass and put in a cloth bag after impurities and dust are removed, and an opening of the cloth bag is tied so that the medicine materials can be reserved for standby application; the medicine materials are soaked in cold boiled water for half an hour, then the soaked medicine materials and clear liquor for soaking the medicine materials are put in a decocting machine together, cold boiled water is injected until the water level is higher than the surfaces of the medicine materials by 35 mm, the medicine materials are decocted for 40 min for the first time, after liquid medicine is filtered out, tepor boiled water is injected again until the water level is higher than the surface of the medicine materials by 32 mm, the medicine materials are decocted for 35 min for the second time, and 1080 ml of 50% traditional Chinese medicine liquid is obtained through mixing and concentration, bagged and sealed for standby application.

Description

A kind of endo-medicine and preparation method for the treatment of alopecia areata

Technical field

The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of endo-medicine for the treatment of alopecia areata, particularly for the endo-medicine of patients with alopecia areata and the field of preparation method.

Background technology

Alopecia areata can betide any age, but common with person between twenty and fifty, both sexes sickness rate no significant difference.Skin lesion shows as circle or the non-cicatricial alopecia of oval, at alopecia areata edge Chang Kejian " exclamation mark " sample hair.Hair comes off all or almost all, is called alopecia totalis.The all hair (comprising chaeta) of whole body all comes off, and is called general de-.Be also shown in row alopecia of crawling.Except without except hair, there are not other extremely in lesion skin.

So, just how finding a kind of medicine effectively can treating alopecia areata, is our current problem in urgent need to solve.

Summary of the invention

The object of this invention is to provide a kind of endo-medicine and preparation method for the treatment of alopecia areata, to solve patients with alopecia areata restorative problem early.This medicine is that have advantages of perfect compatibility, the efficacy of a drug is powerful with common Chinese herbal medicine for raw material, and hit pathogenesis, fully demonstrated nourishing the liver and kidney, the Therapeutic Principle of blood nourishing and hair.

For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide a kind of endo-medicine for the treatment of alopecia areata, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Rehmanniae 1-3 part;

Radix Rehmanniae Preparata 1-3 part;

Fructus Mori 1-3 part;

Caulis Spatholobi 1-3 part;

Caulis Polygoni Multiflori 1-3 part;

Radix Astragali 1-3 part;

Rhizoma Chuanxiong 1-3 part;

Radix Paeoniae Alba 1-3 part;

RHIZONA GASTRODIAE 1-3 part;

Cordyceps 1-3 part;

Herba Ecliptae 1-3 part;

Fructus Chaenomelis 1-3 part.

According to endo-medicine for the treatment of alopecia areata provided by the present invention, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

1 part, the Radix Rehmanniae;

1 part, Radix Rehmanniae Preparata;

1 part, Fructus Mori;

Caulis Spatholobi 1 part;

Caulis Polygoni Multiflori 1 part;

Radix Astragali 1 part;

Rhizoma Chuanxiong 1 part;

The Radix Paeoniae Alba 1 part;

RHIZONA GASTRODIAE 1 part;

Cordyceps 1 part;

Herba Ecliptae 1 part;

Fructus Chaenomelis 1 part.

Treat endo-medicine and the preparation method of alopecia areata, it is characterized in that, described method comprises the steps:

A, 1 part, the one-level Radix Rehmanniae selecting high-quality clean, 1 part, Radix Rehmanniae Preparata, 1 part, Fructus Mori, Caulis Spatholobi 1 part, Caulis Polygoni Multiflori 1 part, Radix Astragali 1 part, Rhizoma Chuanxiong 1 part, the Radix Paeoniae Alba 1 part, RHIZONA GASTRODIAE 1 part, Cordyceps 1 part, Herba Ecliptae 1 part, Fructus Chaenomelis 1 part, after removing impurity and dust respectively, enter tying in cloth bag stand-by;

B, said medicine is put into cold boiled water soak half an hour, and then the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, the cold boiled water injecting medicine 35mm carries out first time decoction 40 minutes, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 32mm carries out second time and decocts 35 minutes, mixing is condensed into the herb liquid 1080 milliliters of 50%, for subsequent use after pack sealing.

Treat endo-medicine and the preparation method of alopecia areata, it is characterized in that, described instructions of taking is: divided by the herb liquid prepared and take for two days, every day potion, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Take medicine 80-110 agent, hair major part has recovered normal.

Medicine for the treatment of alopecia areata provided by the present invention is oral traditional Chinese medicine composition, and it for raw material, gives full play to the property of medicine of each component with common Chinese herbal medicine:

The Radix Rehmanniae, nature and flavor: sweet in the mouth, hardship, cold in nature, there is clearing away heat and cooling blood, effect of moisturizing of promoting the production of body fluid, be used for the treatment of acute calenture, excessive thirst hindered in unconsciousness due to high fever, macule, Tianjin, haematemesis, epistaxis, the metrorrhagia of bleeding due to blood-heat, have blood in stool, the cough of aphtha of the mouth and tongue, laryngopharynx swelling and pain, consumptive fever, traumatic pain, the disease such as carbuncle;

Radix Rehmanniae Preparata, nature and flavor: sweet in the mouth, warm in nature, there is effect that moist, beneficial essence of enriching blood fills out marrow, be used for the treatment of sallow, the dizzy cardiopalmus of blood tiger, menoxenia, collapse that more than, hepatic and renal YIN deficiency, hectic fever night sweat, seminal emission sexual impotence, infertility, soreness of the waist and knees, Hiccough and deaf, the head are dim-sighted, early whitening of beard and hair, quench one's thirst, constipation, dyspnea with rapid and short breath of suffering from a deficiency of the kidney, osteopyrexia and fever, the disease such as severe palpitation;

Fructus Mori, nature and flavor: sweet, sour, cold, there is YIN nourishing of enriching blood, promote the production of body fluid moisturize, tonifying liver, kidney tonifying, the liquid that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., grows effect, be used for the treatment of vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound be thirsty, interior-heat is quenched one's thirst, blood deficiency and constipation, hepatic and renal YIN deficiency, order are dark, the disease such as scrofula, articular instability;

Caulis Spatholobi, nature and flavor: bitter in the mouth, micro-sweet, warm in nature, have effect of relaxing muscles and tendons to promote blood circulation, nourishing blood for regulating menstruation, are used for the treatment of the diseases such as numb hand and foot, quadriplegia, rheumatic arthralgia, menoxenia, dysmenorrhea, amenorrhea;

Caulis Polygoni Multiflori, nature and flavor: sweet micro-hardship, flat, have nourishing heart, calm the nerves, dredging collateral, the effect of dispeling the wind, and are used for the treatment of the diseases such as insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies;

Radix Astragali, nature and flavor: sweet, warm, there is effect of invigorating QI to consolidate the body surface resistance, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation, be used for the treatment of that the deficiency of vital energy is weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty are burst, burst for a long time do not hold back, the disease such as blood deficiency dull yellowish colored skin, interior-heat are quenched one's thirst, chronic nephritis proteinuria, diabetes;

Rhizoma Chuanxiong, nature and flavor: pungent, warm, have that activating QI to alleviate the depression, method wind-dryness are wet, effect of promoting blood circulation and stopping pain, be used for the treatment of that dizzy, hypochondriac pain abdomen pain is revolved in air-cooled headache, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores, menoxenia, abdominal mass are suffered from abdominal pain, breast coerces the diseases such as twinge, tumbling and swelling, rheumatic arthralgia;

The Radix Paeoniae Alba, nature and flavor: bitter, acid, to be slightly cold, have nourish blood and seek, effect of relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver, be used for the treatment of menoxenia, abdominal pain during menstruation, metrorrhagia, spontaneous perspiration, night sweat, side of body rib epigastric pain, limb pain twin, headache, the disease such as dizzy;

RHIZONA GASTRODIAE, nature and flavor: sweet, pungent, flat, nontoxic, have effect of endogenous wind stopping relieving convulsion, suppressing the hyperactive liver sun, dispelling wind and removing obstruction in the collateral, are used for the treatment of the diseases such as anxious chronic infantile convulsion, tic contracture, dizzy, headache, hemiplegia, limb fiber crops, rheumatic arthralgia;

Cordyceps, nature and flavor: sweet, warm, there is lung benefiting kidney, mend effect of marrow, hemostasis and phlegm, be used for the treatment of the disease such as cough due to consumptive disease, haematemesis, sexual impotence, soreness of waist and knee joint, seminal emission, pulmonary tuberculosis hemoptysis, the debilitating chronic cough and asthma of old people, after being ill night sweat, spontaneous perspiration or anemia;

Herba Ecliptae, nature and flavor: sweet in the mouth, acid, cool in nature, there is effect of liver and kidney tonifying, cooling blood for hemostasis, be used for the treatment of deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair, haematemesis, spitting of blood, epistaxis, have blood in stool, dysentery, collapse, leak, the disease such as traumatic hemorrhage, diphtheria, stranguria with turbid discharge, leukorrhagia, pudendum pruritus due to damp pathogen;

Fructus Chaenomelis, nature and flavor: warm in nature, sour in the mouth, have help digestion, anthelmintic, heat clearing away, the effect of dispeling the wind, be used for the treatment of the diseases such as stomachache, dyspepsia, lung-heat dry cough, galactostasis, eczema, parasitic disease, trick spasm pain.

When taking, the herb liquid prepared is divided and within two days, takes, every day potion, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Take medicine 80-110 agent, hair major part has recovered normal.This medicine is that have advantages of perfect compatibility, the efficacy of a drug is powerful with common Chinese herbal medicine for raw material, and hit pathogenesis, fully demonstrated nourishing the liver and kidney, the Therapeutic Principle of blood nourishing and hair.

Detailed description of the invention

Alopecia areata can betide any age, but common with person between twenty and fifty, both sexes sickness rate no significant difference.Skin lesion shows as circle or the non-cicatricial alopecia of oval, at alopecia areata edge Chang Kejian " exclamation mark " sample hair.Hair comes off all or almost all, is called alopecia totalis.The all hair (comprising chaeta) of whole body all comes off, and is called general de-.Be also shown in row alopecia of crawling.Except without except hair, there are not other extremely in lesion skin.

The present invention is exactly treatment for above-mentioned alopecia areata and a kind of Chinese herbal medicine formula proposed, and adopt herb liquid prepared by this formula, good drug efficacy, instant effect, toxic and side effects is little, can effectively treat above-mentioned alopecia areata.Below specific embodiment provided by the present invention is described in detail.

Embodiment 1:

15 grams, the one-level Radix Rehmanniae selecting high-quality clean, 15 grams, Radix Rehmanniae Preparata, 15 grams, Fructus Mori, Caulis Spatholobi 15 grams, Caulis Polygoni Multiflori 15 grams, Radix Astragali 30 grams, Rhizoma Chuanxiong 9 grams, the Radix Paeoniae Alba 15 grams, RHIZONA GASTRODIAE 6 grams, Cordyceps 6 grams, Herba Ecliptae 9 grams, Fructus Chaenomelis 6 grams, after removing impurity and dust respectively, enter tying in cloth bag stand-by; Said medicine is put into after cold boiled water soaks half an hour, and then the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, the cold boiled water injecting medicine 35mm carries out first time decoction 40 minutes, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 32mm carries out second time and decocts 35 minutes, mixing is condensed into the herb liquid 1080 milliliters of 50%, for subsequent use after pack sealing.When taking, the herb liquid prepared is divided and within two days, takes, every day potion, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Take medicine 80-110 agent, hair major part has recovered normal.

Embodiment 2:

16.5 grams, the one-level Radix Rehmanniae selecting high-quality clean, 16.5 grams, Radix Rehmanniae Preparata, 16.5 grams, Fructus Mori, Caulis Spatholobi 16.5 grams, Caulis Polygoni Multiflori 16.5 grams, Radix Astragali 33 grams, Rhizoma Chuanxiong 10 grams, the Radix Paeoniae Alba 16.5 grams, RHIZONA GASTRODIAE 6.5 grams, Cordyceps 6.5 grams, Herba Ecliptae 10 grams, Fructus Chaenomelis 6.5 grams, after removing impurity and dust respectively, enter tying in cloth bag stand-by; Said medicine is put into after cold boiled water soaks half an hour, and then the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, the cold boiled water injecting medicine 35mm carries out first time decoction 40 minutes, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 32mm carries out second time and decocts 35 minutes, mixing is condensed into the herb liquid 1080 milliliters of 50%, for subsequent use after pack sealing.When taking, the herb liquid prepared is divided and within two days, takes, every day potion, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Take medicine 80-90 agent, hair major part has recovered normal.

Embodiment 3:

15 grams, the one-level Radix Rehmanniae selecting high-quality clean, 15 grams, Radix Rehmanniae Preparata, 15 grams, Fructus Mori, Caulis Spatholobi 15 grams, Caulis Polygoni Multiflori 15 grams, Radix Astragali 30 grams, Rhizoma Chuanxiong 9 grams, the Radix Paeoniae Alba 15 grams, RHIZONA GASTRODIAE 6 grams, Cordyceps 6 grams, Herba Ecliptae 9 grams, Fructus Chaenomelis 6 grams, after removing impurity and dust respectively, enter tying in cloth bag stand-by; Said medicine is put into after cold boiled water soaks half an hour, and then the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, the cold boiled water injecting medicine 35mm carries out first time decoction 40 minutes, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 32mm carries out second time and decocts 35 minutes, mixing is condensed into the herb liquid 1080 milliliters of 50%, for subsequent use after pack sealing.When taking, the herb liquid prepared is divided and within two days, takes, every day potion, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Take medicine 80-100 agent, hair major part has recovered normal.

The present invention is through the treatment to nearly one hundred routine patient, and therapeutic effect is remarkable, and toxic and side effects is little, and part allusion quotation shape case is as follows.

Patient: high XX, female, 26 years old, address: Chengdu, Sichuan Province

Illness symptom: first visit on August 18 in 1997.Patient started to find that head has a fritter alopecia in October, 1996, and become sheet by the great development of finger lid and come off, scalp baldness, occasionally itches, do not peel, and once personal Rhizoma Zingiberis Recens wiped treatment outward, and effect does not show.After again with multiple alcohol preparation and take Chinese and western drugs, effect is all undesirable.More than 2 years now, eyebrow, eyelashes were also coming off, anorexia, and two is just general, wrong after menstruation, uneasy sleeping at night, dreaminess.Check: hair, eyebrow, eyelashes about 2/3 come off, scalp light, be dispersed in a little fine hair on birds or animals hair therebetween, remaining hair slightly touches and namely easily comes off.Moderate pulse is weak unable, thin white fur of tongue and sliding, and body of the tongue is light red.Western medicine diagnose is alopecia areata.This is be deficiency of the liver and kindey, blood deficiency alopecia.Control suitable nourishing the liver and kidney, blood nourishing and hair.

Treatment: give top " herb liquid " medical treatment, take medicine January continuously, diet increases, and menstruation has recovered normal, sleep stable comparatively, the fine hair on birds or animals hair of the visible a little new life of scalp portions, former remaining fine hair on birds or animals hair is comparatively front to turn yellow, and complexion changed is dark, thicker, hardening, do not have again and continue to come off.Enter again medicine two months, scalp fine hair on birds or animals hair is existing newborn, and original fine hair on birds or animals hair major part turns yellow or is dark-brown, and thick and stiff, and diet is adjusted, and sleep night and pacified, spirit is happier.Advise it to change and take mulberry paste and Qibao Meiran Dan (being commercially available), take medicine one month, hair major part has recovered normal, only hair and eyebrow color light a little, compared with normal is slightly soft.

Claims (3)

1. can treat an endo-medicine for alopecia areata, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Rehmanniae 1-3 part;

Radix Rehmanniae Preparata 1-3 part;

Fructus Mori 1-3 part;

Caulis Spatholobi 1-3 part;

Caulis Polygoni Multiflori 1-3 part;

Radix Astragali 1-3 part;

Rhizoma Chuanxiong 1-3 part;

Radix Paeoniae Alba 1-3 part;

RHIZONA GASTRODIAE 1-3 part;

Cordyceps 1-3 part;

Herba Ecliptae 1-3 part;

Fructus Chaenomelis 1-3 part.

2. endo-medicine for the treatment of alopecia areata according to claim 1, is characterized in that, each component of described medicine and mass parts thereof are than as follows:

1 part, the Radix Rehmanniae;

1 part, Radix Rehmanniae Preparata;

1 part, Fructus Mori;

Caulis Spatholobi 1 part;

Caulis Polygoni Multiflori 1 part;

Radix Astragali 1 part;

Rhizoma Chuanxiong 1 part;

The Radix Paeoniae Alba 1 part;

RHIZONA GASTRODIAE 1 part;

Cordyceps 1 part;

Herba Ecliptae 1 part;

Fructus Chaenomelis 1 part.

3. the endo-medicine of the treated alopecia areata described in claim 1 or 2 and a preparation method, is characterized in that, described method comprises the steps:

A, according to mass parts than choosing the clean one-level Radix Rehmanniae of high-quality, Radix Rehmanniae Preparata, Fructus Mori, Caulis Spatholobi, Caulis Polygoni Multiflori, Radix Astragali, Rhizoma Chuanxiong, the Radix Paeoniae Alba, RHIZONA GASTRODIAE, Cordyceps, Herba Ecliptae, Fructus Chaenomelis, after removing impurity and dust respectively, enter tying in cloth bag stand-by;

B, said medicine is put into cold boiled water soak half an hour, and then the clear liquor of soaked medicine and soak medicine is put into boiling machine in the lump, the cold boiled water injecting medicine 35mm carries out first time decoction 40 minutes, after leaching medicinal liquid, the tepor boiled water re-injecting medicine 32mm carries out second time and decocts 35 minutes, mixing is condensed into the herb liquid 1080 milliliters of 50%, for subsequent use after pack sealing.