CN105125848A - Traditional Chinese medicine for treating dry eye syndromes - Google Patents
Traditional Chinese medicine for treating dry eye syndromes Download PDFInfo
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- CN105125848A CN105125848A CN201510644413.8A CN201510644413A CN105125848A CN 105125848 A CN105125848 A CN 105125848A CN 201510644413 A CN201510644413 A CN 201510644413A CN 105125848 A CN105125848 A CN 105125848A
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Abstract
The invention relates to traditional Chinese medicine for treating dry eye syndromes. The traditional Chinese medicine is prepared from, by weight, 13 parts of artemisia dubia, 6 parts of folium mori, 12 parts of lotus leaves, 9 parts of poria cocos, 9 parts of raspberries, 6 parts of radix rubiae, 13 parts of circium japonicum and 12 parts of ophiopogon japonicus. According to the traditional Chinese medicine, artemisia dubia can remove heat and cool the blood, the folium mori can dispel wind and heat, clear away the lung heat and improve the eyesight, the lotus leaves can send up the lucid yang, the poria cocos can strengthen the spleen and quiet the heart, the raspberries can tonify the kidneys to strengthen secure essence, the radix rubiae can cool the blood and promote collaterals, the circium japonicum can cool the blood and dissipate blood stasis, and the ophiopogon japonicus can nourish yin to produce body fluid; all the medicines are used together and can achieve the effects of cooling the blood and clearing heat, promoting collaterals and dissipating blood stasis, sending up the lucid yang and nourishing yin to produce the body fluid, and therefore the dry eye syndromes can be effectively treated. Clinical experiments prove that the traditional Chinese medicine can safely and effectively treat the dry eye syndromes.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of xerophthalmia.
Background technology
Xerophthalmia refers to that the tear matter that any reason causes or amount exception or kinetics are abnormal, causes tear film stability to decline, and the general name of various diseases with ophthalmic uncomfortable and (or) eye table organization characteristics of lesion.Also known as angle conjunctival xerosis.Common symptom comprise eyes dry and astringent, easily tired, ophthalmic pruritus, have that foreign body sensation, pain burning sensation, secretions are sticky, aversion to wind, photophobia, to external world stimulate very sensitive; Sometimes eyes are too dry, basic oligodacrya, stimulate reflexive lacrimal secretion on the contrary, and cause and usually shed tears; More severe case eyes can redness, hyperemia, keratinization, corneal epithelium broken skin and have filament to stick, this damage with the passing of time then can cause angle conjunctive disorder, and can affect one's power of vision.
Common symptom is the dry and astringent and foreign body sensation of eye, other symptoms have burn feeling, gargalesthesia, photophobia, hyperemia, bitterly, blurred vision fatiguability, glutinous filamentous secretion thing etc.
Medical material present Research involved in the present invention is as follows:
Subdigitate wormwood herb [another name] wild Artemisia, tea floss, purple bar Artemisia, refer to that leaf Artemisia, water Artemisia, Radix Artemisia ordosicae, rice Artemisia [source] are feverfew subdigitate wormwood herb and the herb without hair subdigitate wormwood herb.Autumn gathers, and using fresh herb or binding are dried.[habitats distribution] is distributed in the ground such as the Inner Mongol, Gansu, Sichuan, Yunnan, Tibet.[nature and flavor] bitter in the mouth; Micro-pungent; Cool in nature.[function cures mainly] heat clearing away; Removing heat from blood; Removing toxic substances; Parasite killing.Main acute calenture; Xerophthalmia; Laryngopharynx swelling and pain; Epistaxis; Itching eruption due to wind-heat in blood; Know parasitosis.[usage and dosage] takes orally: decoct soup 9-15g; Or endure cream painting.[extracts] " China's book on Chinese herbal medicine ".
The leaf that Folium Mori [source] are moraceae plants Mulberry.Gather after the Frost's Descent in 10 ~ November through the leaf of frost, removing withe and impurity, dry.[habitats distribution] is distributed in all parts of the country.[nature and flavor] bitter in the mouth; Sweet; Cold in nature.[function cures mainly] dispelling wind and heat pathogens; Lung heat clearing; Improving eyesight.Main anemopyretic cold; Pathogenic wind-warm from the beginning of, fever and headache, perspiration and aversion to wind, cough chest pain; Or dryness of the lung dry cough without phlegm; Dry throat and mouth; Wind heat and liver-yang are disturbed; Conjunctival congestion and swelling pain.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g; Or enter ball, loose.External: appropriate, decocts washing or smashes deposited.[extracts] " China's book on Chinese herbal medicine ".
Folium Nelumbinis [source] this product is the dried leaves of nymphaeaceae plant lotus NelumbonuciferaGaertn..[nature and flavor] are bitter, flat.[return through] returns liver, spleen, stomach warp.[function cures mainly] clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding.For multiple hemorrhage and puerperal blood faints.[usage and dosage] 3 ~ 9g; Fresh goods 15 ~ 30g; Burnt FOLIUM NELUMBINIS 3 ~ 6g.
Poria [source] this product is the dry sclerotia of On Polyporaceae Poria Poriacocos (Schw.) Wolf.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.[usage and dosage] 9 ~ 15g.
Fructus Rubi [source] this product is the dry fruit of Rosaceae rubus rubus chingii Hu RubuschingiiHu.[nature and flavor] are sweet, sour, temperature.[return through] returns kidney, urinary bladder channel.[function cures mainly] kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination.For enuresis due to deficiency of the kidney, frequent micturition, impotence and premature ejaculation, emission and spermatorrhea.[usage and dosage] 6 ~ 12g.
Radix Rubiae [source] this product is the dry root and rhizome of Maguireothamnus speciosus Radix Rubiae RubiacordifoliaL..[nature and flavor] are bitter, cold.[return through] returns Liver Channel.[function cures mainly] removing heat from blood, hemostasis, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, metrorrhagia, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.[usage and dosage] 6 ~ 9g.
Radix Cirsii Japonici [source] is Compositae artichoke plant Radix Cirsii Japonici CirsiumjaponicumDC., is used as medicine with herb and root.[nature and flavor] are sweet, cool.[function cures mainly] cooling blood for hemostasis, dissipating blood stasis for subsidence of swelling.Cure mainly: epistaxis, spitting of blood, spit blood, hematuria, dysfunctional uterine hemorrhage, postpartum hemorrhage, hepatitis, nephritis, mastitis, traumatic injury; Traumatic hemorrhage is controlled in external, carbuncle furuncle and phyma poison.[usage and dosage] 0.5 ~ 1 liang; External fresh goods is appropriate, mashes deposited affected part.
Radix Ophiopogonis [source] this product is the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogonjaponicus (Thunb.) Ker-Gawl..[nature and flavor] are sweet, and micro-hardship, is slightly cold.[return through] GUIXIN, lung, stomach warp.[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.[usage and dosage] 6 ~ 12g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of xerophthalmia, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing xerophthalmia.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a Chinese medicine for xerophthalmia, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: subdigitate wormwood herb 13 parts, 6 parts, Folium Mori, 12 parts, Folium Nelumbinis, 9 parts, Poria, Fructus Rubi 9 parts, 6 parts, Radix Rubiae, Radix Cirsii Japonici 13 parts, Radix Ophiopogonis 12 parts.
Below in conjunction with theory of Chinese medical science, beneficial effect of the present invention is described:
Inventor thinks, human body asthenia of essence and blood, caused by liver and kidney deficiency, can not sending nutrient upward to eye, thus can see asthenopia, eye discharge many, have the malaise symptoms such as the dry and astringent pain discomfort of foreign body sensation, eyes, blurred vision.The site of pathological change of xerophthalmia is at eye, and the internal organs attribute of disease is mainly liver, kidney and spleen, because liver opening at eye, if liver blood is difficult its key of supplementing nutrition, liver-yang is partially high, holds under the arm on wind and disturbs key clearly, can attack order by fire-transformation; If feelings will hindered, can not reach by bar, the liver failing to maintain the normal flow of QI, depression and stagnation of QI, also can fire-transformation superinverse; Weakness of the spleen and stomach, dysfunction of the spleen in transportation, water-damp not being transformed, flees meridians, clear YANG failing to ascend, turbid YIN failing to descend, inverse and on disturb key clearly, above various reasons all can cause lacrimal passage smooth, thus causes primary disease.
The present invention uses: subdigitate wormwood herb clearing away heat and cooling blood; Folium Mori dispelling wind and heat pathogens, lung heat clearing tomorrow; Folium Nelumbinis sending up the lucid YANG; Poria spleen invigorating mind calming; Fructus Rubi supplementing the kidney to control the nocturnal; Radix Rubiae removing heat from blood stimulates the menstrual flow; Radix Cirsii Japonici cool the blood dissipate blood stasis; Radix Ophiopogonis YIN nourishing and the production of body fluid promoting.All medicines share, and play heat clearing and blood cooling altogether, effect of the dissipating blood stasis that stimulates the menstrual flow, sending up the lucid YANG, YIN nourishing and the production of body fluid promoting, effectively treat xerophthalmia.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects patients with dry eye 106 example of outpatient clinic altogether between in May ,-2015 in April, 2013, all meet xerophthalmia diagnostic criteria.Above-mentioned case is divided at random treatment and contrast two groups.In treatment group 53 example, man 32 example, female 21 example; 18 ~ 71 years old age.In matched group 53 example, man 28 example, female 25 example; 18 ~ 72 years old age.Two groups of patients there was no significant difference (P > 0.05) in symptom etc. before age, sex, treatment, has comparability.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.1 week course for the treatment of.
Matched group externally used compound sodium chloride eye drop (manufacturer: Wuhan Wujing Medicine Co., Ltd), uses according to its description, 1 week course for the treatment of.
All patients do ophthalmology routine examination, fluorescent staining scoring, Tear function test before the treatment, check, observe contrast therapy result after treating 4 courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: sears optical, asthenopia, have the transference cures such as foreign body sensation, lacrimal secretion is normal;
Effective: sears optical, asthenopia, to have the symptom integral such as foreign body sensation to alleviate more than 50%, lacrimal secretion has increase;
Effective: sears optical, asthenopia, to have the symptom integral such as foreign body sensation to alleviate more than 25%, lacrimal secretion increases to some extent;
Invalid: symptom is without improvement, and lacrimal secretion is without increase.
3.2 therapeutic outcomes are in table 1
The table 1 liang clinical total effects of group compares
Be used for the treatment of xerophthalmia cure rate by the visible the present invention of above result high, there is the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: subdigitate wormwood herb 13 grams, 6 grams, Folium Mori, 12 grams, Folium Nelumbinis, 9 grams, Poria, Fructus Rubi 9 grams, 6 grams, Radix Rubiae, Radix Cirsii Japonici 13 grams, Radix Ophiopogonis 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of xerophthalmia.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: subdigitate wormwood herb 13 grams, 6 grams, Folium Mori, 12 grams, Folium Nelumbinis, 9 grams, Poria, Fructus Rubi 9 grams, 6 grams, Radix Rubiae, Radix Cirsii Japonici 13 grams, Radix Ophiopogonis 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of xerophthalmia.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 3
Take: subdigitate wormwood herb 13 grams, 6 grams, Folium Mori, 12 grams, Folium Nelumbinis, 9 grams, Poria, Fructus Rubi 9 grams, 6 grams, Radix Rubiae, Radix Cirsii Japonici 13 grams, Radix Ophiopogonis 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of xerophthalmia.Oral, every bu morning, noon and afternoon take for three times.
Claims (4)
1. be used for the treatment of a Chinese medicine for xerophthalmia, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: subdigitate wormwood herb 13 parts, 6 parts, Folium Mori, 12 parts, Folium Nelumbinis, 9 parts, Poria, Fructus Rubi 9 parts, 6 parts, Radix Rubiae, Radix Cirsii Japonici 13 parts, Radix Ophiopogonis 12 parts.
2. a kind of Chinese medicine being used for the treatment of xerophthalmia as claimed in claim 1, it is characterized in that, its preparation method is: take: subdigitate wormwood herb 13 parts, 6 parts, Folium Mori, 12 parts, Folium Nelumbinis, 9 parts, Poria, Fructus Rubi 9 parts, 6 parts, Radix Rubiae, Radix Cirsii Japonici 13 parts, Radix Ophiopogonis 12 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of xerophthalmia as claimed in claim 1, it is characterized in that, its preparation method is: take: subdigitate wormwood herb 13 parts, 6 parts, Folium Mori, 12 parts, Folium Nelumbinis, 9 parts, Poria, Fructus Rubi 9 parts, 6 parts, Radix Rubiae, Radix Cirsii Japonici 13 parts, Radix Ophiopogonis 12 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of xerophthalmia as claimed in claim 1, it is characterized in that, its preparation method is: take: subdigitate wormwood herb 13 parts, 6 parts, Folium Mori, 12 parts, Folium Nelumbinis, 9 parts, Poria, Fructus Rubi 9 parts, 6 parts, Radix Rubiae, Radix Cirsii Japonici 13 parts, Radix Ophiopogonis 12 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20180137240A (en) * | 2017-06-16 | 2018-12-27 | 인제대학교 산학협력단 | Compositions for Preventing or Treating Diseases Associated with Reduction of Mucin Comprising Water Soluble Fraction of Water Soluble Extraction of Artemisia capillaris |
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| CN1772177A (en) * | 2005-11-03 | 2006-05-17 | 何伟 | Orally taken medicine for treating climacteric xerophthalmia and its prepn |
| CN104324222A (en) * | 2014-11-27 | 2015-02-04 | 崔合芳 | Traditional Chinese medicine preparation for treating Qi and Yin deficiency type dry eye syndromes |
| CN104383229A (en) * | 2014-12-06 | 2015-03-04 | 邹士东 | Traditional Chinese medicine composition for treating yin deficiency and yang excess type xerophthalmia |
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2015
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Patent Citations (3)
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| CN1772177A (en) * | 2005-11-03 | 2006-05-17 | 何伟 | Orally taken medicine for treating climacteric xerophthalmia and its prepn |
| CN104324222A (en) * | 2014-11-27 | 2015-02-04 | 崔合芳 | Traditional Chinese medicine preparation for treating Qi and Yin deficiency type dry eye syndromes |
| CN104383229A (en) * | 2014-12-06 | 2015-03-04 | 邹士东 | Traditional Chinese medicine composition for treating yin deficiency and yang excess type xerophthalmia |
Non-Patent Citations (1)
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20180137240A (en) * | 2017-06-16 | 2018-12-27 | 인제대학교 산학협력단 | Compositions for Preventing or Treating Diseases Associated with Reduction of Mucin Comprising Water Soluble Fraction of Water Soluble Extraction of Artemisia capillaris |
| KR101994275B1 (en) * | 2017-06-16 | 2019-06-28 | 인제대학교 산학협력단 | Compositions for Preventing or Treating Diseases Associated with Reduction of Mucin Comprising Water Soluble Fraction of Water Soluble Extraction of Artemisia capillaris |
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Application publication date: 20151209 |