CN105109215A - Ink jet printing tray and printing method for printing sensitive layer of biochemical sensor - Google Patents
Ink jet printing tray and printing method for printing sensitive layer of biochemical sensor Download PDFInfo
- Publication number
- CN105109215A CN105109215A CN201510568187.XA CN201510568187A CN105109215A CN 105109215 A CN105109215 A CN 105109215A CN 201510568187 A CN201510568187 A CN 201510568187A CN 105109215 A CN105109215 A CN 105109215A
- Authority
- CN
- China
- Prior art keywords
- printing
- ink
- pallet
- inkjet printing
- silicon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Ink Jet (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
Abstract
The invention discloses an ink jet printing tray and printing method for printing the sensitive layer of a biochemical sensor. The ink jet printing tray includes a wafer support, a positioning slider arranged on the wafer support, a tensioning screw, a group of paper width sensor identification marks and a group of tray installation positioning marks; the wafer support is used for bearing a wafer to be printed; the tensioning screw is used for adjusting the position of the positioning slider; the positioning slider is used for fixing the wafer to be printed; the paper width sensor identification marks are detected by a paper width sensor on an ink-jet printer, so that a printing area can be determined; and the tray installation positioning marks are in alignment fit with insertion slot position marks on the ink-jet printer, so that the positioning of the ink jet printing tray when the ink jet printing tray is inserted into the ink-jet printer can be realized. With the ink jet printing tray and printing method of the invention adopted, the positioning accuracy of printing can be improved, and printing operation can be facilitated.
Description
Technical field
The present invention relates to silica-based biochemical sensor and make field, for printing inkjet printing pallet and the Method of printing of biochemical sensor sensitive layer.
Background technology
Along with the process of Internet of Things development, comprise the various sensors microminiaturizations of biochemical sensor, integrated trend is more and more obvious, also more and more higher to the performance requirement of all kinds of microsensor.Present stage, generally utilize silica-base material and micro-processing technology to make microsensor.As a large class of microsensor, miniature biochemical sensor is widely used in the field such as medical treatment, environmental monitoring, and such sensor is primarily of sensing arrangement and biochemical sensitive layer composition.For this kind of device, how to prepare biochemical sensitive layer at silicon substrate surface is a Research Challenges, also well not current method.At present, in sensor base, the method for preparative chemistry sensitive layer mainly contains chemical vapour deposition technique, sol-gel process, molecular self-assembling method etc.These methods can not deposit Special complex shape film or by multiple different thin-film integration in same substrate.The mode of employing inkjet printing can solve the problem just, namely commercial ink-jet printer is carried out repacking and enables to print at substrate surface, and biochemical sensitive material is deployed into ink, enables to be injected in fiber waveguide substrate to form film.Be CN103558196A at publication number, denomination of invention is in the technical scheme disclosed in " preparing the method for detection of organic phosphorus pesticide visual biosensor based on inkjet technology ", prepared by described sensitive thin film inkjet printing methods, but do not relate to the transformation of ink-jet printer.This preparation method directly utilizing ink-jet printer, positioning precision is low.Therefore, on the basis of commercial printer that can print CD, design one and can load the inkjet printing pallet needing the substrate printed, realizing hi-Fix printing function is silica-based biochemical sensor field and other field problem demanding prompt solution.
Summary of the invention
Main purpose of the present invention is to overcome the deficiencies in the prior art, provides a kind of inkjet printing pallet for printing biochemical sensor sensitive layer and Method of printing, improves the positioning precision printed, and is convenient to printing.
For achieving the above object, the present invention is by the following technical solutions:
A kind of inkjet printing pallet for printing biochemical sensor sensitive layer, comprise silicon-wafer holder, be arranged on the positioning sliding block on described silicon-wafer holder, holding screw, telltale mark installed by one group of wide sensor identification marking of paper and one group of pallet, described silicon-wafer holder is for carrying silicon chip to be printed, described holding screw is for regulating the position of described positioning sliding block, described positioning sliding block is used for fixing silicon chip to be printed, described paper wide sensor identification marking is for detecting for the wide sensor of paper on ink-jet printer and determining the region of printing, described pallet is installed telltale mark and is coincide to the slot position mark on ink-jet printer for contraposition, to realize the location when described inkjet printing pallet being inserted ink-jet printer.
Further:
Described silicon-wafer holder is provided with the circular groove for placing silicon chip to be printed, and the upper surface of described silicon-wafer holder is provided with some irregular grooves.
The material of described inkjet printing pallet is ABS plastic, and thickness is 2 ~ 3mm, preferred 2.2mm.
The diameter of described circular groove is the diameter being suitable for arrangement 4 cun of silicon chips, the printing starting point 10mm of distance from top vertical direction, the printing starting point 13mm of left side distance horizontal direction.
It is two right that described paper wide sensor identification marking has, the a pair paper wide sensor identification marking wherein arranged in the horizontal direction detects for the wide sensor of paper supply the scope determining the horizontal direction printed, and a pair paper wide sensor identification marking vertically arranged detects for the wide sensor of paper supply the scope determining the vertical direction printed.
A kind of biochemical sensor sensitive layer Method of printing, comprises the following steps:
A. the jetting fluid of preparation containing biological or chemical sensitive material is as the ink of inkjet printing;
B. use described inkjet printing pallet that silicon chip is loaded into ink-jet printer to print.
Also comprise: before the printing, silicon chip surface hydrophilicity-imparting treatment is carried out to silicon chip.
Described silicon chip surface hydrophilicity-imparting treatment adopts oxygen plasma surface treating method, and radio-frequency power is 100W, and oxygen flow is 200mL/min, and modification time is 0 ~ 15min, preferred 10min.
Described chemical-sensitive material is polyvinyl alcohol, polystyrene, polyvinyl chloride, polyethylene, the at least one of polyethylene terephthalate, preferably polyethylene alcohol, at least one in polystyrene and polyethylene, the solvent of described chemical-sensitive material is water or absolute ethyl alcohol, described biological sensitive materials is the aqueous solution of bioactive molecule, the preferred protein aqueous solution, and dilute with phosphate buffer, the jetting fluid of described biology or chemical-sensitive material is according to the viscosity of marking ink and surface tension preparation, the surface tension of ink is 30 ~ 50mNm-1, viscosity is 1 ~ 3.0mPa.s.
Beneficial effect of the present invention:
Inkjet printing pallet of the present invention can significantly improve the positioning precision of printing, one group of wide sensor identification marking of paper and one group of pallet installation telltale mark are set, precisely can orient the scope that will print easily, improve print quality, and be extremely convenient to user and carry out printing, improve printing effect; Adopt positioning sliding block and holding screw, realize fixing silicon chip in adjustable mode, suitability is good, and stationarity is good, and reliability is strong.Meanwhile, the space layout of inkjet printing pallet is compact, reasonable.Preferred embodiment can obtain further advantage.Such as, the design of irregular groove increases its skin-friction force, makes inkjet printing pallet by non-slip when ink-jet printer driven roller, can also alleviate the weight of inkjet printing pallet.In a preferred embodiment, the oxygen plasma adopted carries out surface hydrophilic process to silicon chip, can reach super hydrophilic effect.The biological or chemical sensitive layer prepared by the present invention is even, and thickness can be controlled by printing times.On the whole, use the present invention, printing precision is high, reproducible, realizes hi-Fix and prints, be with a wide range of applications and potentiality to be exploited in waveguide biochemical sensor field.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the inkjet printing pallet of the embodiment of the present invention;
Fig. 2 is the schematic diagram of the positioning sliding block of the inkjet printing pallet of the embodiment of the present invention;
Fig. 3 a and Fig. 3 b is the printing error analysis of the embodiment of the present invention;
Fig. 4 is the design sketch that the embodiment of the present invention prepares polyvinyl alcohol sensitive thin film.
Detailed description of the invention
Below embodiments of the present invention are elaborated.It is emphasized that following explanation is only exemplary, instead of in order to limit the scope of the invention and apply.
See Fig. 1 to Fig. 2, embodiment is provided for laying silicon chip (4 cun of silicon chips) to carry out the inkjet printing pallet of inkjet printing.During use, first can carry out silicon chip surface hydrophilicity-imparting treatment; Based on the viscosity of ink-jet printing ink and the jetting fluid of surface tension preparation biological or chemical sensitive material; Finally inkjet printing is carried out to silicon chip, obtain biological or chemical sensitive layer.
As shown in Figure 1 to Figure 2, in one embodiment, inkjet printing pallet comprises 4 cun of silicon-wafer holder, 1, one group of wide sensor identification marking 2a-2d of paper, one group of pallet installs telltale mark 3a-3b, positioning sliding block 5 and holding screw 6.Wherein, 4 cun of silicon-wafer holder 1 comprise the round groove of placement 4 cun of silicon chips, some irregular grooves, the contact point 4 of CDR optical disc tray sensor and the inclined-plane of support front end.Some irregular grooves can increase its skin-friction force, make inkjet printing pallet by non-slip when ink-jet printer driven roller, and alleviate the weight of inkjet printing pallet.The inclined-plane of support front end can make inkjet printing pallet in non-manual situation, can enter ink-jet printer smoothly.The wide sensor identification marking 2a-2d mono-of paper has 4, is separately positioned on 4 cun of silicon-wafer holder 1.When printing, the scope of the horizontal direction printed determined by the wide sensor of paper of the inkjet printer head first wide sensor identification marking 2a and 2c of test paper, the wide sensor identification marking 2b and 2d of test paper determines the print range of vertical direction again, thus determines the region of printing.The round groove of 4 cun of silicon-wafer holder 1 is produced in this print area, and its diameter is slightly larger than the diameter of 4 cun of silicon chips, and the printing starting point 10mm of distance from top vertical direction, the left side is apart from the printing starting point 13mm of horizontal direction.Its degree of depth is larger than silicon wafer thickness, preferred 1.2mm.Pallet is installed telltale mark 3a-3b and is always had 2.When printing, the bottom slot of inkjet printing pallet along the CD/DVD guide rail of piezoelectric ink jet printer (as EpsonR230 type) can be inserted, until matching that telltale mark 3a-3b on printing pallet and CD/DVD guide rail mark, which achieves its positioning function.Positioning sliding block 5 is arranged on 4 cun of silicon-wafer holder 1, clamps silicon chip realize the fixing of silicon chip by holding screw 6.The material of inkjet printing pallet is ABS plastic, and thickness is 2 ~ 3mm, preferred 2.2mm.Embodiment can work on the piezoelectric ink jet printer with optical disk printing function.
What silicon chip surface hydrophilicity-imparting treatment preferably adopted is oxygen plasma surface-treated method.Preferably, radio-frequency power 80W ~ 600w is selected, more preferably 100w; Oxygen flow: 100 ~ 300mL/min, preferred 200mL/min; Modification time is 0 ~ 15min, more preferably 10min.
The optional at least one from polyvinyl alcohol, polystyrene, polyvinyl chloride, polyethylene, polyethylene terephthalate of chemical-sensitive material, at least one in preferably polyethylene alcohol, polystyrene and polyethylene.The solvent of described chemical-sensitive material selects water, ethanol.Described biological sensitive materials can be the aqueous solution of bioactive molecule, the preferred protein aqueous solution, and dilutes with phosphate buffer.The jetting fluid of described biology or chemical-sensitive material can according to the viscosity of commercial inkjet marking ink and surface tension preparation, and the surface tension of ink is 30 ~ 50mNm
-1, viscosity is 1 ~ 3.0mPa.s.
In one embodiment, a kind of biochemical sensor sensitive layer Method of printing, comprises the following steps:
A. the jetting fluid of preparation containing biological or chemical sensitive material is as the ink of inkjet printing;
B. use a kind of inkjet printing pallet of previous embodiment that silicon chip is loaded into ink-jet printer to print.
In following application example, prepare the biochemical sensitive layer of optical waveguide biochemical sensor based on inkjet technology, comprise following flow process:
Step 1: the 4 cun of silicon chips carrying out hydrophilicity-imparting treatment are positioned in the circular groove printed on pallet, by the position regulating described holding screw to regulate described positioning sliding block, 4 cun of silicon chips are positioned in circular groove;
Step 2: preparation jetting fluid also cleans print cartridge, the material formulation that will print becomes jetting fluid to inject print cartridge;
Step 3: draw a design on AutoCAD according to biochemical sensor sensitive layer position and shape;
Step 4: inserted by the bottom slot of inkjet printing pallet along the CD/DVD guide rail of EpsonR230, until print matching that telltale mark on pallet and CD/DVD guide rail mark, starts printing.
Example 1 prepares polyvinyl alcohol film
Referring to figs. 1 through Fig. 2 the palm designing and producing inkjet printing pallet and spray paint, according to design positioning sliding block and holding screw are engaged in 4 cun of silicon-wafer holder.
Select EpsonR230 ink-jet printer, be arranged on inkjet printing pallet by common four cun of silicon chips and carry out printing error analysis, the printing error result of horizontal direction and vertical direction respectively as shown in Figure 3 a and Figure 3 b shows.Fig. 3 a illustrates that the printing error of horizontal direction is from-0.021mm to 0.014mm; Fig. 3 b illustrates that the printing error of vertical direction prints the increase of starting point along with distance and increases, and on silicon chip, the place of 80mm reaches 1.245mm.The error of the horizontal direction of visible printing is less, and the error of vertical direction can carry out error compensation, can realize the positioning printing of degree of precision.
To the silicon chip printed be needed to be placed in low pressure plasma cleaning machine, select radio-frequency power 100w, oxygen flow 200mL/min, carries out surface treatment 10 minutes.The contact angle of silicon chip is now 5.4 °, close to realizing super hydrophilic effect.With the AutoCAD software development figure that ad-hoc location prints on silicon chip, and this figure is inserted in Word document.
Polyvinyl alcohol is dissolved in deionized water in 80 DEG C of situations, and preparation quality mark is the solution of 1.5%.Cooling solution at normal temperatures, regulates poly-vinyl alcohol solution with absolute ethyl alcohol, makes its surface tension and viscosity close to Epson ink.Then the metre filter of 100 μm is used.Take out the print cartridge absolute ethyl alcohol wash clean of EpsonR230 ink-jet printer, the solution syringe prepared is injected print cartridge.
Surface treated silicon chip is fixed on inkjet printing pallet.The bottom slot of inkjet printing pallet along the CD/DVD guide rail of EpsonR230 is inserted, until matching that the telltale mark printed on pallet and CD/DVD guide rail mark.The method of printing word document conveniently starts to print.The effect printed as shown in Figure 4.
Above content combines concrete/preferred embodiment further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention; without departing from the inventive concept of the premise; its embodiment that can also describe these makes some substituting or modification, and these substitute or variant all should be considered as belonging to protection scope of the present invention.
Claims (9)
1. one kind for printing the inkjet printing pallet of biochemical sensor sensitive layer, it is characterized in that, comprise silicon-wafer holder, be arranged on the positioning sliding block on described silicon-wafer holder, holding screw, telltale mark installed by one group of wide sensor identification marking of paper and one group of pallet, described silicon-wafer holder is for carrying silicon chip to be printed, described holding screw is for regulating the position of described positioning sliding block, described positioning sliding block is used for fixing silicon chip to be printed, described paper wide sensor identification marking is for detecting for the wide sensor of paper on ink-jet printer and determining the region of printing, described pallet is installed telltale mark and is coincide to the slot position mark on ink-jet printer for contraposition, to realize the location when described inkjet printing pallet being inserted ink-jet printer.
2. inkjet printing pallet as claimed in claim 1, it is characterized in that, described silicon-wafer holder is provided with the circular groove for placing silicon chip to be printed, and the upper surface of described silicon-wafer holder is provided with some irregular grooves.
3. inkjet printing pallet as claimed in claim 1, it is characterized in that, the material of described inkjet printing pallet is ABS plastic, and thickness is 2 ~ 3mm, preferred 2.2mm.
4. inkjet printing pallet as claimed in claim 3, it is characterized in that, the diameter of described circular groove is the diameter being suitable for arrangement 4 cun of silicon chips, the printing starting point 10mm of distance from top vertical direction, the printing starting point 13mm of left side distance horizontal direction.
5. inkjet printing pallet as claimed in claim 1, it is characterized in that, it is two right that described paper wide sensor identification marking has, the a pair paper wide sensor identification marking wherein arranged in the horizontal direction detects for the wide sensor of paper supply the scope determining the horizontal direction printed, and a pair paper wide sensor identification marking vertically arranged detects for the wide sensor of paper supply the scope determining the vertical direction printed.
6. a biochemical sensor sensitive layer Method of printing, is characterized in that, comprises the following steps:
A. the jetting fluid of preparation containing biological or chemical sensitive material is as the ink of inkjet printing;
B. use the inkjet printing pallet as described in any one of claim 1 to 5 that silicon chip is loaded into ink-jet printer to print.
7. biochemical sensor sensitive layer Method of printing as claimed in claim 6, is characterized in that, comprising: before the printing, carry out silicon chip surface hydrophilicity-imparting treatment to silicon chip.
8. biochemical sensor sensitive layer Method of printing as claimed in claim 7, is characterized in that, described silicon chip surface hydrophilicity-imparting treatment adopts oxygen plasma surface treating method, radio-frequency power is 100W, oxygen flow is 200mL/min, and modification time is 0 ~ 15min, preferred 10min.
9. biochemical sensor sensitive layer Method of printing as claimed in claims 6 or 7, it is characterized in that, described chemical-sensitive material is polyvinyl alcohol, polystyrene, polyvinyl chloride, polyethylene, the at least one of polyethylene terephthalate, preferably polyethylene alcohol, at least one in polystyrene and polyethylene, the solvent of described chemical-sensitive material is water or absolute ethyl alcohol, described biological sensitive materials is the aqueous solution of bioactive molecule, the preferred protein aqueous solution, and dilute with phosphate buffer, the jetting fluid of described biology or chemical-sensitive material is according to the viscosity of marking ink and surface tension preparation, the surface tension of ink is 30 ~ 50mNm
-1, viscosity is 1 ~ 3.0mPa.s.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510568187.XA CN105109215B (en) | 2015-09-08 | 2015-09-08 | Inkjet printing pallet and Method of printing for printing biochemical sensor sensitive layer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510568187.XA CN105109215B (en) | 2015-09-08 | 2015-09-08 | Inkjet printing pallet and Method of printing for printing biochemical sensor sensitive layer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105109215A true CN105109215A (en) | 2015-12-02 |
| CN105109215B CN105109215B (en) | 2018-08-24 |
Family
ID=54657424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510568187.XA Expired - Fee Related CN105109215B (en) | 2015-09-08 | 2015-09-08 | Inkjet printing pallet and Method of printing for printing biochemical sensor sensitive layer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105109215B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106004096A (en) * | 2016-05-13 | 2016-10-12 | 清华大学深圳研究生院 | Ink-jet printing tray for printing sensitive layer of quartz crystal sensor |
| CN106433310A (en) * | 2016-09-12 | 2017-02-22 | 清华大学深圳研究生院 | Ink, sensitive layer, biosensor and preparation method of ink |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1495036A (en) * | 2002-07-10 | 2004-05-12 | 佳能株式会社 | Recorder |
| CN1583406A (en) * | 2003-08-20 | 2005-02-23 | 佳能株式会社 | Recording apparatus |
| CN1732724A (en) * | 2002-10-30 | 2006-02-08 | 因弗内斯医疗有限公司 | Apparatus and method for controlling registration of print steps in a continuous process for the manufacture of electrochemical sensors |
| CN1840354A (en) * | 2005-03-31 | 2006-10-04 | 精工爱普生株式会社 | Tray and recording apparatus |
| JP2007045084A (en) * | 2005-08-12 | 2007-02-22 | Seiko Epson Corp | Printer |
| US20070109341A1 (en) * | 2005-11-17 | 2007-05-17 | Seiko Epson Corporation | Printer and detachable printer tray |
| JP2008074071A (en) * | 2006-09-25 | 2008-04-03 | Seiko Epson Corp | Determination method of tray, recording apparatus, and liquid jetting device |
| CN101341030A (en) * | 2005-12-22 | 2009-01-07 | 皇家飞利浦电子股份有限公司 | Ink jet device for the positioning of a substance onto a substrate, method for the positioning of a substance onto a substrate and use of an ink jet device |
| CN101856916A (en) * | 2009-04-01 | 2010-10-13 | 精工爱普生株式会社 | Label machine, media processing apparatus and media processing system |
| CN103558196A (en) * | 2013-11-04 | 2014-02-05 | 哈尔滨工业大学 | Method for preparing visual biosensor for detecting organophosphorus pesticides based on ink-jet printing technology |
-
2015
- 2015-09-08 CN CN201510568187.XA patent/CN105109215B/en not_active Expired - Fee Related
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1495036A (en) * | 2002-07-10 | 2004-05-12 | 佳能株式会社 | Recorder |
| CN1732724A (en) * | 2002-10-30 | 2006-02-08 | 因弗内斯医疗有限公司 | Apparatus and method for controlling registration of print steps in a continuous process for the manufacture of electrochemical sensors |
| CN1583406A (en) * | 2003-08-20 | 2005-02-23 | 佳能株式会社 | Recording apparatus |
| CN1840354A (en) * | 2005-03-31 | 2006-10-04 | 精工爱普生株式会社 | Tray and recording apparatus |
| JP2007045084A (en) * | 2005-08-12 | 2007-02-22 | Seiko Epson Corp | Printer |
| US20070109341A1 (en) * | 2005-11-17 | 2007-05-17 | Seiko Epson Corporation | Printer and detachable printer tray |
| CN101341030A (en) * | 2005-12-22 | 2009-01-07 | 皇家飞利浦电子股份有限公司 | Ink jet device for the positioning of a substance onto a substrate, method for the positioning of a substance onto a substrate and use of an ink jet device |
| JP2008074071A (en) * | 2006-09-25 | 2008-04-03 | Seiko Epson Corp | Determination method of tray, recording apparatus, and liquid jetting device |
| CN101856916A (en) * | 2009-04-01 | 2010-10-13 | 精工爱普生株式会社 | Label machine, media processing apparatus and media processing system |
| CN103558196A (en) * | 2013-11-04 | 2014-02-05 | 哈尔滨工业大学 | Method for preparing visual biosensor for detecting organophosphorus pesticides based on ink-jet printing technology |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106004096A (en) * | 2016-05-13 | 2016-10-12 | 清华大学深圳研究生院 | Ink-jet printing tray for printing sensitive layer of quartz crystal sensor |
| CN106004096B (en) * | 2016-05-13 | 2018-05-04 | 清华大学深圳研究生院 | A kind of inkjet printing pallet for being used to print quartz crystal sensor sensitive layer |
| CN106433310A (en) * | 2016-09-12 | 2017-02-22 | 清华大学深圳研究生院 | Ink, sensitive layer, biosensor and preparation method of ink |
| CN106433310B (en) * | 2016-09-12 | 2021-03-12 | 清华大学深圳研究生院 | Ink, sensitive layer, biosensor and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105109215B (en) | 2018-08-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6004446B2 (en) | Multilayer microfluidic probe head and manufacturing method thereof | |
| CN105109215A (en) | Ink jet printing tray and printing method for printing sensitive layer of biochemical sensor | |
| CN102574260B (en) | For the apparatus and method of precision edge finishing | |
| Riegler et al. | Observation of a monolayer phase transition on the meniscus in a Langmuir-Blodgett transfer configuration | |
| CN103477217A (en) | Electronic device including calibration information and method of using the same | |
| CN106596645A (en) | Single-molecule-controlled graphene nanometer-pore DNA sequenator | |
| CN107121055B (en) | A kind of three-dimensional scaling method of eddy current displacement sensor array | |
| CN104999180B (en) | Based on the ceramic microstructures 3D Method of printing that nanosecond-psec-femtosecond laser is compound | |
| CN104209153A (en) | Preparation method of paper micro-fluidic chips | |
| CN109738337B (en) | Testing device and method for testing 3D contact angle value of solid material by top view method | |
| CN104212711B (en) | Electronic sensor and the crto gene method based on electronic sensor | |
| CN105403716B (en) | Fixing device cooperating on micro-fluidic chip observation and micro-fluidic chip observation system | |
| US9707583B2 (en) | Systems and methods for detecting substrate alignment during a printing process | |
| NL2011009C2 (en) | Method and device for receiving a droplet. | |
| CN110208219A (en) | A kind of surface phasmon optical fiber probe and preparation method thereof based on electrochemical polymerization molecular imprinting technology | |
| Zou et al. | Fast and accurate measurement of diffusion coefficient by Taylor’s dispersion analysis | |
| CN103943777B (en) | The method that organic semiconductor/ferroelectricity is combined resistance changing film is prepared in a kind of controllable temperature spin coating | |
| CN100394183C (en) | Locating device and its locating method for biochip | |
| JP2016176842A (en) | Thin slice sample preparation device | |
| CN106959332B (en) | The automatic fine sampling device and its control method of electrophoresis detection instrument | |
| TW200500149A (en) | Apparatus and method for substrate coating | |
| Yang et al. | A novel solution-auto-introduction electrophoresis microchip based on capillary force | |
| CN103913143A (en) | Micro-milling-cutter cutting edge blunt circle measurement device and method | |
| CN205027649U (en) | A sample dish and laser analysis appearance for laser analysis appearance | |
| CN210037532U (en) | Scanning type substrate surface detection device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: 518055 Guangdong city of Shenzhen province Nanshan District Xili of Tsinghua Applicant after: Graduate School at Shenzhen, Tsinghua University Address before: 518000 Guangdong city in Shenzhen Province, Nanshan District City Xili Shenzhen Tsinghua Campus of Tsinghua University Applicant before: Graduate School at Shenzhen, Tsinghua University |
|
| COR | Change of bibliographic data | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180824 Termination date: 20210908 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |