CN105106416A - Medicine composition for treating nasosinusitis - Google Patents
Medicine composition for treating nasosinusitis Download PDFInfo
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- CN105106416A CN105106416A CN201510598694.8A CN201510598694A CN105106416A CN 105106416 A CN105106416 A CN 105106416A CN 201510598694 A CN201510598694 A CN 201510598694A CN 105106416 A CN105106416 A CN 105106416A
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Abstract
The invention relates to a medicine composition for treating nasosinusitis and a preparation method of the medicine composition. The defects that the treating effect of existing medicine is poor, and the recurrence rate is high are overcome. The medicine composition is mainly prepared from centipeda minima, honeysuckle, flos magnolia, fructus xanthii, chrysanthemum indicum, radix angelicae dahuricae, asarum, rhizoma chuanxiong, dried rehmannia roots, ephedra, Chinese ligusticum rhizome, herb mint, scrophulariae, radix platycodi and borneol. Meanwhile, the preparation method of the medicine composition is provided. The medicine composition for treating nasosinusitis and the preparation method can be used for the field of manufacturing of functional masks.
Description
Technical field
The present invention relates to a kind of drug regimen for prevention and therapy sinusitis, particularly relate to a kind of drug regimen being used for the treatment of sinusitis.
Background technology
Sinusitis (SINUSITIS) is the disease that a kind of multi-pathogenesis refractory is healed.Feature is nasal obstruction, headache, vexed, the rhinorrhea of brain, serious meeting impels sinus mucosa swelling, nasal sinuses opening is easily blocked, impact breathing, olfactory sensation, nasal sinuses inner air do not circulate, the pus nasal mucus of thickness flows backwards and blocks Eustachian tube position at ductus nasopharyngeus portion opening, causes the complication such as otitis media and middle hydrotis.
Sinusitis is the disease that the serious relapse rate in the whole world is high, and development rapidly, wherein patients with chronic sinusitis accounts for more than 80%, it is 4.98 hundred million that the end of the year 2012 showed current global sinusitis in patients by International Red Cross's organisations publish data, expecting the year two thousand thirty will reach 600,000,000, increase by 6,000,000 patients every year.The Red Cross Society of China organizes statistical data to show Chinese sinusitis in patients 1.9 hundred million, and forward youth and student crowd extend, and sinusitis has become the very serious large disease threatening human health.Only universal precaution treatment sinusitis medicine in 2012 is mostly be made by chemical substance chemical method, and it costly; Weak effect, relapse rate is high, extreme influence health of human body.The Therapeutic Method of nearly hundred kinds on market, really medicable and few.
Summary of the invention
The technical problem that first the present invention will solve is that to overcome present technique effect poor, the deficiency that relapse rate is high, provide a kind of can the function mask of effective prevention and therapy sinusitis, its principle utilizes mask to be become by medicine transform gas to carry out circulation treatment to nasal sinuses.
The present invention's technical problem first to be solved is realized by following scheme;
Be used for the treatment of a drug regimen for sinusitis, each raw material primarily of following weight portion is made: Herba Centipedae 5-9 part Flos Lonicerae 10-20 part Flos Magnoliae 3-10 part Fructus Xanthii 3-10 part Flos Chrysanthemi Indici 10-15 part Radix Angelicae Dahuricae 3-10 part Herba Asari 1.5-9 part Rhizoma Chuanxiong 3-10 part Radix Rehmanniae 10-30 part Herba Ephedrae 1.5-10 part Rhizoma Ligustici 3-10 part Herba Pogostemonis 5-10 part Herba Menthae 3-6 part Radix Scrophulariae 9-15 part Radix Platycodonis 3-10 part Borneolum Syntheticum 0.15-0.3 part
Preferably, the present invention contains following component by weight: Herba Centipedae 3 portions of Flos Loniceraes 3 parts of Flos Magnoliaes 3 portions of Fructus Xanthii 2.5 parts of Flos Chrysanthemi Indicis 2.5 parts of Radixs Angelicae Dahuricae 2.4 parts of Herba Asaris 2.1 parts of Rhizoma Chuanxiongs 1.5 parts of Radix Rehmanniae 1.5 portions of Herba Ephedraes 1.5 parts of Rhizoma Ligusticis 1.6 portions of Herba Pogostemoniss 0.9 portion of Herba Menthae 0.9 portion of Radix Scrophulariae 0.6 part of Radix Platycodonis 0.3 part of Borneolum Syntheticum 0.3 part.
The present invention can produce following good effect compared with the prior art; The present invention is for major ingredient with Herba Centipedae Flos Lonicerae Flos Magnoliae Fructus Xanthii Flos Chrysanthemi Indici Radix Angelicae Dahuricae Herba Asari; Rhizoma Chuanxiong Radix Rehmanniae Herba Ephedrae Rhizoma Ligustici Herba Pogostemonis Herba Menthae Radix Scrophulariae Radix Platycodonis Borneolum Syntheticum is the brand-new function mask of one that adjuvant is made.
Herba Centipedae: main containing compositions such as Palmic acid Herba Taraxaci sterol ester, acetic acid Herba Taraxaci sterol ester, Herba Taraxaci sterin, nonadecanoic acid inearnatyl alcohol esters.Antiallergic; Cough-relieving, eliminates the phlegm, relievings asthma, have inhibitory action to tubercule bacillus, has good therapeutic efficiency to rhinitis, sinusitis, nasal polyp.
Flos Lonicerae: mainly containing volatile oil, terpenoid etc., can resisting pathogenic microbes, and antitoxin, antiinflammatory, antipyretic, promote inflammatory cell phagocytic function, blood fat reducing, central excitation has suppression to a certain degree to Hemolytic streptococcus.
Flos Magnoliae: containing nopinene, Magnolin, aromadendrene, Y biondii(Pamp)D.L.Fu. fat element A etc., Anhydroalkannin, anti-platelet aggregation, antimicrobial, analgesia cold-dispelling, clearing the nasal passage improves microcirculation.
Fructus Xanthii: containing linoleic acid, Palmic acid, stearic acid, Xanthostrumarin, energy antimicrobial, blood vessel dilating strengthens vascular permeability, antithrombase, to reduce in peripheral blood total white blood cells and cholesterol and triglyceride can be recovered to normal level, low dose of reinforcement respiratory movement, heavy dose of suppression respiratory movement.
Flos Chrysanthemi Indici: containing yejuhua lactone, chrysanthemol, scalable blood flow and the function of resisting myocardial ischemia such as chrysanthetriol, suppress phosphodiesterase, anti-platelet clotting, resisting pathogenic microbes, antipyretic enhancing phagocyte phagocytic function, suppresses golden yellow staphylococcus plasma-coagulase to be formed.
The Radix Angelicae Dahuricae: imperatorin, angelicotoxin, byak-angelicin, oxypeucedanin etc. can shorten clotting time, expansion coronary vasodilator, subsides a swelling, pus of dispelling, stuffy nose relieving plug, fluid stopping tears.
Herba Asari: containing nimbecetin kaempferol 3-O-β-D-pyranglucoside, asarone etc., can make normal body temperature be down to normal following, to cellular immunization and humoral immunization, all there is obvious inhibitory action, antihistamine and antiallergic action and have certain antibacterial and obvious rhinovirus effect.
Rhizoma Chuanxiong: containing ferulic acid, the compositions such as river indole 3-butylidenephthalide, myrcene, ligustrazine, daucosterol, coronary blood flow can be increased, have protective effect to cardiac muscle and reperfusion injury, be improved microcirculation, cerebral circulation and cerebral ischemia, improve blood system, strengthen immune system; The airway constriction that leukotriene, histamine, PGE2 can be suppressed to cause, has the effect of antitumor, anti-radiation.
Radix Rehmanniae: can improve immunologic function containing catalpol, acteoside, Martynoside., butyl alcohol etc., have antifungal, antiallergic, blood sugar lowering, has protection in various degree to cardiovascular system.
Herba Ephedrae: containing sanedrine, left-handed, the left-handed demethyl ephedrine of pseudoephedrine, Herba Ephedrae oxazolone etc., have respiratory system relieving asthma, antitussive, eliminate the phlegm make sweat gland secretion strengthen there is obvious diuresis, antiinflammatory action.
Rhizoma Ligustici: containing ferulic acid, aromadendrene, borneol acetate, neocindilide, ligustilide etc.Smooth muscle, blood pressure lowering blood vessel dilating can be suppressed, suppress isolated frog heart to improve myocardial ischemia perfusion injury; Improve hypoxia-bearing capability and there is the effects such as antibacterial, anti-hepatic injury, anti-bag-like virus, antioxidation.
Herba Pogostemonis: there is antibacterial and calcium antagonism containing patchouli alcohol, western car alkene, Herba Pogostemonis glycol etc.; Nasosinusitis headache, nasal obstruction brain can be gone vexed.
Herba Menthae: containing levorotatory menthol, isomenthone, pulegone, menthyl acetate, different Rui Fuling, Herba Menthae isoflavone aglycone, Alecrim acid etc. can stimulating central nervous system, to be made skin capillary vascular expansion by peripheral nerve, promote sweat gland secretion, increase heat radiation; Sweating and heat resolving, local action can make the Cold receptor of skin mucosa react and have stimulation, blood vessel dilating to skin; Have respiratory system and eliminate the phlegm and good cough-relieving promotion skin absorption Anhydroalkannin antimicrobial.
Radix Scrophulariae: containing Harpagide, harpagoside, Radix Scrophulariae three fat glycosides, Radix Scrophulariae kind glycosides, aucubin, Radix Scrophulariae cyclic ethers, geniposide, Sai Sitan glycosides F, remove caffeoyl verbascoside, verbascoside etc.; energy is antipyretic, antibacterial, dispel pain, antiinflammatory stuffy nose relieving chamber; Ischemic myocardium, blood pressure lowering blood glucose.
Radix Platycodonis: main containing platycodin A platycodoside C Platycodin D Platycodin D 2 platycogenic acid A platycogenic acid B platycogenic acid C, α-spinaterol etc.Can eliminating phlegm and relieving cough, antiinflammatory, antiulcer, edema can decreased heart rate, suppress breathe, body-temp. reducing cholesterol reducing.
Borneolum Syntheticum: containing L-Borneol, has obvious calmness, analgesic activity, promotes growth and the division of neurogliocyte.
Each raw material used in the present invention can be bought from shop of Chinese medicines, and its quality is pharmaceutical grade.
The present invention provide simultaneously a kind of preparation method being used for the treatment of the drug regimen of sinusitis its comprise the steps that Radix Scrophulariae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Herba Asari, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Platycodonis control to pulverize at the super-micro wall-broken of 60 objects to each raw material by (1) respectively, cell-wall breaking ratio be less than or equal to 90% (2) by Fructus Xanthii, Flos Magnoliae, Herba Menthae, Herba Centipedae, Herba Pogostemonis, Herba Ephedrae, Flos Chrysanthemi Indici, Flos Lonicerae carry out 10 order pulverizing respectively; Each effective ingredient Hybrid Heating is fried the Borneolum Syntheticum powder adding equal portions quantity stir (3) will be best for realizing described material component at least one of the present invention.
Detailed description of the invention
Further describe the present invention below in conjunction with specific embodiment, advantage and disadvantage of the present invention will along with description clearly.But these case study on implementation are only exemplary; any restriction is not formed to scope of the present invention; art technology director it should be understood that; can modify to the details of technical solution of the present invention and form lower without departing from the spirit and scope of the present invention or replace, but these amendments and replacement all fall within protection scope of the present invention.
Embodiment 1
A kind of drug regimen being used for the treatment of sinusitis: it is made in the steps below: Herba Centipedae 9kg, Flos Lonicerae 20kg, Flos Magnoliae 10kg, Fructus Xanthii 10kg, Flos Chrysanthemi Indici 15kg, Radix Angelicae Dahuricae 10kg, Herba Asari 9kg, Rhizoma Chuanxiong 10kg, Radix Rehmanniae 30kg, Herba Ephedrae 10kg, Rhizoma Ligustici 10kg, Herba Pogostemonis 10kg, Herba Menthae 6kg, Radix Scrophulariae 15kg, Radix Platycodonis 10kg, Borneolum Syntheticum 0.3kg.Wherein Radix Scrophulariae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Herba Asari, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Platycodonis are controlled to pulverize at 60 object super-micro wall-brokens to each raw material respectively, cell-wall breaking ratio is less than or equal to 90%, by Fructus Xanthii, Flos Magnoliae, Herba Menthae, Herba Centipedae, Herba Pogostemonis, Herba Ephedrae, Flos Chrysanthemi Indici, Flos Lonicerae carry out 10 order pulverizing respectively; By each effective ingredient mixing and stirring, heating fries, Borneolum Syntheticum pulverizing is mixed with all active substance, carry out sonic oscillation mixing, and stir, form semi-finished product, then semi-finished product are got the measured non-woven bag of ventilation of portion (27.6 grams) loading 10*12cm by equal portions quantity, evenly sew it up, be contained in (antiseptic gauze centreless mask) in special mask and form product.
Embodiment 2
A kind of drug regimen being used for the treatment of sinusitis: it is made in the steps below: Herba Centipedae 5kg, Flos Lonicerae 10kg, Flos Magnoliae 3kg, Fructus Xanthii 3kg, Flos Chrysanthemi Indici 10kg, Radix Angelicae Dahuricae 3kg, Herba Asari 1.5kg, Rhizoma Chuanxiong 3kg, Radix Rehmanniae 10kg, Herba Ephedrae 1.5kg, Rhizoma Ligustici 3kg, Herba Pogostemonis 5kg, Herba Menthae 3kg, Radix Scrophulariae 9kg, Radix Platycodonis 3kg, Borneolum Syntheticum 0.15kg.Wherein Radix Scrophulariae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Herba Asari, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Platycodonis are controlled to pulverize at 60 object super-micro wall-brokens to each raw material respectively, cell-wall breaking ratio is less than or equal to 90%, by Fructus Xanthii, Flos Magnoliae, Herba Menthae, Herba Centipedae, Herba Pogostemonis, Herba Ephedrae, Flos Chrysanthemi Indici, Flos Lonicerae carry out 10 order pulverizing respectively; By each effective ingredient mixing and stirring, heating fries, Borneolum Syntheticum pulverizing is mixed with all active substance, carry out sonic oscillation mixing, and stir, form semi-finished product, then semi-finished product are got the measured non-woven bag of ventilation of portion (27.6 grams) loading 10*12cm by equal portions quantity, evenly sew it up, be contained in (antiseptic gauze centreless mask) in special mask and form product.
Embodiment 3
A kind of drug regimen being used for the treatment of sinusitis: it is made in the steps below: Herba Centipedae 3kg, Flos Lonicerae 3kg, Flos Magnoliae 3kg, Fructus Xanthii 2.5kg, Flos Chrysanthemi Indici 2.5kg, Radix Angelicae Dahuricae 2.4kg, Herba Asari 2.1kg, Rhizoma Chuanxiong 1.5kg, Radix Rehmanniae 1.5kg, Herba Ephedrae 1.5kg, Rhizoma Ligustici 1.6kg, Herba Pogostemonis 0.9kg, Herba Menthae 0.9kg, Radix Scrophulariae 0.6kg, Radix Platycodonis 0.3kg, Borneolum Syntheticum 0.3kg.Wherein Radix Scrophulariae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Herba Asari, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Platycodonis are controlled to pulverize at 60 object super-micro wall-brokens to each raw material respectively, cell-wall breaking ratio is less than or equal to 90%, by Fructus Xanthii, Flos Magnoliae, Herba Menthae, Herba Centipedae, Herba Pogostemonis, Herba Ephedrae, Flos Chrysanthemi Indici, Flos Lonicerae carry out 10 order pulverizing respectively; By each effective ingredient mixing and stirring, heating fries, Borneolum Syntheticum pulverizing is mixed with all active substance, carry out sonic oscillation mixing, and stir, form semi-finished product, then semi-finished product are got the measured non-woven bag of ventilation of portion (27.6 grams) loading 10*12cm by equal portions quantity, evenly sew it up, be contained in (antiseptic gauze centreless mask) in special mask and form product.
Claims (3)
1. be used for the treatment of a drug regimen for sinusitis, it is characterized in that containing following component by weight: Herba Centipedae 5-9 part Flos Lonicerae 10-20 part Flos Magnoliae 3-10 part Fructus Xanthii 3-10 part Flos Chrysanthemi Indici 10-15 part Radix Angelicae Dahuricae 3-10 part Herba Asari 1.5-9 part Rhizoma Chuanxiong 3-10 part Radix Rehmanniae 10-30 part Herba Ephedrae 1.5-10 part Rhizoma Ligustici 3-10 part Herba Pogostemonis 5-10 part Herba Menthae 3-6 part Radix Scrophulariae 9-15 part Radix Platycodonis 3-10 part Borneolum Syntheticum 0.15-0.3 part.
2. a kind of drug regimen being used for the treatment of sinusitis according to claim 1, is characterized in that containing following component by weight: Herba Centipedae 3 parts, Flos Lonicerae 3 parts, Flos Magnoliae 3 parts, Fructus Xanthii 2.5 parts, Flos Chrysanthemi Indici 2.5 parts, the Radix Angelicae Dahuricae 2.4 parts, Herba Asari 2.1 parts of Rhizoma Chuanxiongs 1.5 parts, Radix Rehmanniae 1.5 parts, 1.5 parts, Herba Ephedrae, Rhizoma Ligustici 1.6 parts, Herba Pogostemonis 0.9 portion of Herba Menthae 0.9 part, Radix Scrophulariae 0.6 part, Radix Platycodonis 0.3 part, Borneolum Syntheticum 0.3 part.
3. a kind of drug regimen being used for the treatment of sinusitis according to claim 2, is characterized in that comprising the steps:
(1) Radix Scrophulariae, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Herba Asari, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Platycodonis are controlled to pulverize at 60 object super-micro wall-brokens to each raw material respectively, cell-wall breaking ratio is less than or equal to 90%
(2) by Fructus Xanthii, Flos Magnoliae, Herba Menthae, Herba Centipedae, Herba Pogostemonis, Herba Ephedrae, Flos Chrysanthemi Indici, Flos Lonicerae carry out 10 order pulverizing respectively; By each effective ingredient mixing and stirring, heating fries.
(3) Borneolum Syntheticum pulverizing is mixed with all active substance, carry out sonic oscillation mixing and stir, form semi-finished product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510598694.8A CN105106416A (en) | 2015-09-18 | 2015-09-18 | Medicine composition for treating nasosinusitis |
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| CN201510598694.8A CN105106416A (en) | 2015-09-18 | 2015-09-18 | Medicine composition for treating nasosinusitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038703A (en) * | 2016-07-29 | 2016-10-26 | 吴强 | Traditional Chinese medicine ointment for treating nasosinusitis and preparation method thereof |
| CN107823399A (en) * | 2017-12-15 | 2018-03-23 | 贵州健瑞安药业有限公司 | A kind of preparation method for being used to preventing or treating the external preparation of rhinitis, liniment and ointment |
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| CN101904901A (en) * | 2009-06-04 | 2010-12-08 | 王兆山 | Medicament for treating chronic purulent sinusitis |
| CN103239511A (en) * | 2012-05-30 | 2013-08-14 | 李玲玲 | Traditional Chinese medicine composition for treating allergic rhinitis |
| CN103142785A (en) * | 2013-01-26 | 2013-06-12 | 苏甲臣 | Rhinitis treatment medicine |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038703A (en) * | 2016-07-29 | 2016-10-26 | 吴强 | Traditional Chinese medicine ointment for treating nasosinusitis and preparation method thereof |
| CN107823399A (en) * | 2017-12-15 | 2018-03-23 | 贵州健瑞安药业有限公司 | A kind of preparation method for being used to preventing or treating the external preparation of rhinitis, liniment and ointment |
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Application publication date: 20151202 |