CN106038703A - Traditional Chinese medicine ointment for treating nasosinusitis and preparation method thereof - Google Patents
Traditional Chinese medicine ointment for treating nasosinusitis and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Abstract
The invention discloses traditional Chinese medicine ointment for treating nasosinusitis and a preparation method thereof. The traditional Chinese medicine ointment is prepared through blending a traditional Chinese medicine composition and an ointment coagulating matrix, wherein the traditional Chinese medicine composition mainly contains the following ingredients in parts by weight: 8-12 parts of herba centipedae, 0.3-0.7 part of croton cream, 8-12 parts of tribulus terrestris, 8-12 parts of lily magnolia, 2-4 parts of herba Asari, 0.4-0.6 part of musk, 8-12 parts of spina gleditsiae, 13-18 parts of fructus xanthil, 1-3 parts of borneol and 8-12 parts of radix angelicae. Through reasonably combining a variety of traditional Chinese medicines, both symptoms and root causes are treated, the effects of expelling wind and cold pathogens, opening orifices and relieving itching and reducing swelling and easing pain are achieved, and thus the nasosinusitis can be healed. In the form of ointment, the prepared traditional Chinese medicine ointment can be directly smeared in nasal cavities, so that effective ingredients of the medicines can directly infiltrate affected parts through pores, the acting time of the medicines can be prolonged, the use is convenient, the treatment effect is good, and the cure rate reaches 92%; the total effective rate reaches 98%, and recurrence is difficult after cure.
Description
Technical field
The present invention relates to tcm field, particularly relate to a kind of Chinese medicinal ointment treating sinusitis and preparation method thereof.
Background technology
Sinusitis is the nonspecific inflammation of sinus mucosa, for a kind of nose section common frdquently encountered disease, can be divided into acute and chronic two
Kind, acute sinusitis is many by caused by upper respiratory tract infection, and antibacterial infects can fall ill simultaneously with virus, and chronic sinusitis is often by multiple
Nasal sinuses is got involved simultaneously.
The cause of disease of sinusitis is a lot.Doctor trained in Western medicine is thought, fatigue, catching cold is caused by wet, malnutrition, vitamin deficiency etc.
Systemic resistance power declines, and is all the cause of disease causing sinusitis.Additionally, life, working environment unholiness, nose diseases block Dou Kou
Sinotunnel c omplex, hinders drain and the ventilation of nasal sinuses, closes on the infection focus of organ, injury of paranasal sinus or foreign body and enters nasal sinuses, trip
Swimming diving is improper, causes sewage to clamp-on nasal sinuses etc., and iatrogenic nasal cavity is filled out thing indwelling time and caused local excitation after for a long time, continues
Send out and infect and hinder hole mouth drain and ventilation etc., be also responsible for sinusitis.
Modern Western medicine treatment sinusitis common drug is the antibiotic medicine such as penicillins, cephalosporins, vasoconstriction
Agent, mucus eccritic, antihistaminic etc., if headache or local pain are violent, can suitable tranquilizer or analgesics.These medicines
Side effect is relatively big, is easily generated Drug resistance, and therapeutic effect is undesirable, easy recurrent exerbation.Improve nasal sinuses drainage treatment nasal sinuses
Inflammation, the conventional medicine collunarium containing 1% ephedrine, shrinks nasal cavity, improves drain, but also cure the symptoms, not the disease, it is impossible to radical cure, only rise
To mitigation.Puncture and irrigation of maxillary sinus is also the common method of western medical treatment sinusitis, and acute antritis is preferably at whole body
Implement after resolution of symptoms, topical acute inflammation basic controlling, inject antiseptic solution after flushing, but the method on the one hand patient is relatively
For misery, the most easily recurrent exerbation, it is impossible to play the effect of thoroughly radical cure.
Traditional Chinese medicine therapy sinusitis is generally with awakening consciousness, heat-clearing and toxic substances removing, damp eliminating evacuation of pus as principle, the most existing grey
Ears or side handles of a utensil tea, Flos Magnoliae Folium Perillae tea etc., but the most preferable to the therapeutic effect of sinusitis in prior art.
Summary of the invention
The present invention is directed to the above-mentioned problems in the prior art, it is provided that a kind of Chinese medicinal ointment treating sinusitis, it is possible to have
Effect treatment sinusitis, treatment is convenient, and drug effect is gone directly focus, and cure rate is high, has no side effect.
It is a still further object of the present invention to provide the preparation method of a kind of Chinese medicinal ointment treating sinusitis, it is possible to used
Convenient, and can effectively treat the Chinese medicinal ointment of sinusitis.
Other purposes with some for achieving the above object, the present invention adopts the following technical scheme that
A kind of Chinese medicinal ointment treating sinusitis, is in harmonious proportion by Chinese medicine composition and solidifying cream base matter and is prepared from, wherein, described in
Drug composition mainly comprises the component of following weight portion:
Herba Centipedae 8-12, Semen Crotonis Pulveratum 0.3-0.7, Fructus Tribuli 8-12, Flos Magnoliae 8-12, Herba Asari 2-4, Moschus 0.4-0.6, soap
Fructus Gleditsia acupuncture 8-12, Fructus Xanthii 13-18, Borneolum Syntheticum 1-3 and Radix Angelicae Dahuricae 8-12；
Preferably, in the Chinese medicinal ointment of described treatment sinusitis, described Chinese medicine composition mainly comprises following weight portion
Component:
Herba Centipedae 10, Semen Crotonis Pulveratum 0.5, Fructus Tribuli 10, Flos Magnoliae 10, Herba Asari 3, Moschus 0.5, Spina Gleditsiae 10, Fructus Xanthii 15,
Borneolum Syntheticum 2 and the Radix Angelicae Dahuricae 10.
Preferably, in the Chinese medicinal ointment of described treatment sinusitis, described solidifying cream base matter mainly includes waiting the white of weight portion
At least one in vaseline, lanoline and Oleum Sesami；Described solidifying cream base matter is 0.8-1.2 with the mass ratio of Chinese medicine composition:
1。
Preferably, in the Chinese medicinal ointment of described treatment sinusitis, described Chinese medicine composition also includes following weight portion
Component:
Herba Ephedrae 2-4, Rhizoma Et Radix Notopterygii 2-4, Radix Platycodonis 3-5, Rhizoma Ligustici 2-4, Radix Luffae 4-6 and Radix Cynanchi Atrati 2-4.
Preferably, in the Chinese medicinal ointment of described treatment sinusitis, described Chinese medicine composition also includes following weight portion
Component:
Herba Ephedrae 3, Rhizoma Et Radix Notopterygii 3, Radix Platycodonis 4, Rhizoma Ligustici 3, Radix Luffae 5 and Radix Cynanchi Atrati 3.
The preparation method of a kind of Chinese medicinal ointment treating sinusitis, wherein, mainly comprises the steps that
Step 6.1, by Herba Centipedae, Semen Crotonis Pulveratum, Fructus Tribuli, Flos Magnoliae, Herba Asari, Moschus, Spina Gleditsiae, Fructus Xanthii and the Radix Angelicae Dahuricae
Drying and crushing, is ground to more than 200 mesh, obtains medicated powder I；
Step 6.2, white vaseline, lanoline, Oleum Sesami Hybrid Heating are become thick paste, more than borneol and grinding to 200 mesh, add
Thick paste dissolves, is subsequently adding medicated powder I and is in harmonious proportion uniformly, receive cream, obtain the Chinese medicinal ointment of described treatment sinusitis.
The preparation method of a kind of Chinese medicinal ointment treating sinusitis, wherein, mainly comprises the steps that
Step 7.1, by Herba Centipedae, Semen Crotonis Pulveratum, Fructus Tribuli, Flos Magnoliae, Herba Asari, Moschus, Spina Gleditsiae, Fructus Xanthii, the Radix Angelicae Dahuricae, fiber crops
Huang, Rhizoma Et Radix Notopterygii, Radix Platycodonis, Rhizoma Ligustici, Radix Luffae and Radix Cynanchi Atrati drying and crushing, be ground to more than 200 mesh, obtains medicated powder II；
Step 7.2, white vaseline, lanoline, Oleum Sesami Hybrid Heating are become thick paste, more than borneol and grinding to 200 mesh, add
Thick paste dissolves, is subsequently adding medicated powder II and is in harmonious proportion uniformly, receive cream, obtain the Chinese medicinal ointment of described treatment sinusitis.
The present invention at least includes following beneficial effect: first, and the present invention utilizes the traditional Chinese medical science five elements and dialectical theory, it is believed that nasal sinuses
The scorching cause of disease is many due to insufficiency of lung-QI, instability of surface, and wind and cold is taken advantage of a weak point, lung opening at nose, pathogen conflicting with vital QI, and lung qi must not lead to tune,
Body fluid stops gathering, and causes nasal obstruction, rhinocnesmus, sneeze, watery nasal discharge, olfactory sensation decline, headache, dizziness.
In the present invention, Herba Centipedae, dispersing wind-cold, clearing the nasal passage, cough-relieving；Semen Crotonis Pulveratum, eliminating phlegm sore-throat relieving, phagedenoma；Fructus Tribuli, OK
The stasis of blood is dispelled stagnant, antipruritic；Flos Magnoliae, dispersing wind and cold, clearing the nasal passage；Herba Asari, relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, sensible；Moschus, have one's ideas straightened out, dredging collateral, dissipate
The merit of the stasis of blood；Spina Gleditsiae, subside a swelling poison holding, evacuation of pus；Fructus Xanthii, dispersing wind-cold, clearing the nasal passage, pain relieving；Borneolum Syntheticum, logical all keys, reducing swelling and alleviating pain；
The Radix Angelicae Dahuricae, fragrant odour, can lead to nine orifices, evacuation of pus granulation promoting, pain relieving.The present invention by above plurality of Chinese reasonable compatibility, giving consideration to both the incidental and fundamental,
Reach expelling wind and cold, sensible antipruritic, the effect of reducing swelling and alleviating pain, make sinusitis be cured.
Ointment, by the Chinese medicine composition for the treatment of sinusitis being prepared as the form of ointment, can directly be spread upon by the present invention
In nasal cavity, make effective ingredient pass through pore and directly infiltrate through affected part, the long action time of medicine can be extended, easy to use,
Therapeutic effect is good, and cure rate is high.
According to clinical statistics, Chinese medicinal ointment of the present invention reaches 92% to the cure rate of sinusitis, and total effective rate reaches
98%, and control difficulty in relapse after healing.
Part is embodied by the further advantage of the present invention, target and feature by description below, and part also will be by this
Invention research and practice and be understood by the person skilled in the art.
Detailed description of the invention
Below the present invention is elaborated, with make those of ordinary skill in the art refer to can be real according to this after this specification
Execute.
A kind of Chinese medicinal ointment treating sinusitis, is in harmonious proportion by Chinese medicine composition and solidifying cream base matter and is prepared from, wherein, described in
Drug composition mainly comprises the component of following weight portion: Herba Centipedae 8-12, Semen Crotonis Pulveratum 0.3-0.7, Fructus Tribuli 8-12, Flos Magnoliae 8-
12, Herba Asari 2-4, Moschus 0.4-0.6, Spina Gleditsiae 8-12, Fructus Xanthii 13-18, Borneolum Syntheticum 1-3 and Radix Angelicae Dahuricae 8-12.Described solidifying cream base
Matter is customary adjuvant used in preparation Chinese medicinal ointment.
The preparation method of described Chinese medicinal ointment mainly comprises the steps that
Step 6.1, by Herba Centipedae, Semen Crotonis Pulveratum, Fructus Tribuli, Flos Magnoliae, Herba Asari, Moschus, Spina Gleditsiae, Fructus Xanthii and the Radix Angelicae Dahuricae
Drying and crushing, is ground to more than 200 mesh, obtains medicated powder I.
Step 6.2, white vaseline, lanoline, Oleum Sesami Hybrid Heating are become thick paste, more than borneol and grinding to 200 mesh, add
Thick paste dissolves, is subsequently adding medicated powder I and is in harmonious proportion uniformly, receive cream, obtain the Chinese medicinal ointment of described treatment sinusitis.
Embodiment 1
A kind of Chinese medicinal ointment treating sinusitis, is in harmonious proportion by Chinese medicine composition and solidifying cream base matter and is prepared from, wherein, described in
Drug composition mainly comprises the component of following weight portion: Herba Centipedae 10, Semen Crotonis Pulveratum 0.5, Fructus Tribuli 10, Flos Magnoliae 10, Herba Asari 3,
Moschus 0.5, Spina Gleditsiae 10, Fructus Xanthii 15, Borneolum Syntheticum 2 and the Radix Angelicae Dahuricae 10.Described solidifying cream base matter is by waiting the white vaseline of weight portion, sheep
Hair fat and Oleum Sesami mix, and described solidifying cream base matter is 1: 1 with the mass ratio of Chinese medicine composition.
1, by Herba Centipedae, Semen Crotonis Pulveratum, Fructus Tribuli, Flos Magnoliae, Herba Asari, Moschus, Spina Gleditsiae, Fructus Xanthii and Radix Angelicae Dahuricae xeraphium
Broken, it is ground to 220 mesh, obtains medicated powder I.
2, white vaseline, lanoline, Oleum Sesami Hybrid Heating are become thick paste, borneol and grinding to 220 mesh, add in thick paste molten
Solve, be subsequently adding medicated powder I and be in harmonious proportion uniformly, receive cream, obtain the Chinese medicinal ointment of described treatment sinusitis.
Embodiment 2
A kind of Chinese medicinal ointment treating sinusitis, is in harmonious proportion by Chinese medicine composition and solidifying cream base matter and is prepared from, wherein, described in
Drug composition mainly comprises the component of following weight portion: Herba Centipedae 8, Semen Crotonis Pulveratum 0.4, Fructus Tribuli 12, Flos Magnoliae 12, Herba Asari 2, Moschus moschiferous
Perfume 0.4, Spina Gleditsiae 12, Fructus Xanthii 13, Borneolum Syntheticum 3 and the Radix Angelicae Dahuricae 12.Described solidifying cream base matter is by waiting the white vaseline of weight portion, Pilus Caprae seu Ovis
Fat and Oleum Sesami mix, and described solidifying cream base matter is 1.1: 1 with the mass ratio of Chinese medicine composition.
1, by Herba Centipedae, Semen Crotonis Pulveratum, Fructus Tribuli, Flos Magnoliae, Herba Asari, Moschus, Spina Gleditsiae, Fructus Xanthii and Radix Angelicae Dahuricae xeraphium
Broken, it is ground to 200 mesh, obtains medicated powder I.
White vaseline, lanoline, Oleum Sesami Hybrid Heating are become thick paste, borneol and grinding to 200 mesh, add in thick paste and dissolve,
It is subsequently adding medicated powder I and is in harmonious proportion uniformly, receive cream, obtain the Chinese medicinal ointment of described treatment sinusitis.
Embodiment 3
A kind of Chinese medicinal ointment treating sinusitis, is in harmonious proportion by Chinese medicine composition and solidifying cream base matter and is prepared from, wherein, described in
Drug composition mainly comprises the component of following weight portion: Herba Centipedae 10, Semen Crotonis Pulveratum 0.5, Fructus Tribuli 10, Flos Magnoliae 10, Herba Asari 3,
Moschus 0.5, Spina Gleditsiae 10, Fructus Xanthii 15, Borneolum Syntheticum 2, the Radix Angelicae Dahuricae 10, Herba Ephedrae 3, Rhizoma Et Radix Notopterygii 3, Radix Platycodonis 4, Rhizoma Ligustici 3, Radix Luffae 5 and white
Common vetch 3.Wherein, Herba Ephedrae, dispersing wind-cold, depressed lung-energy dispersing, inducing diuresis to remove edema；Rhizoma Et Radix Notopterygii, expelling wind and cold, pain relieving；Radix Platycodonis, lung qi dispersing, eliminates the phlegm, arranges
Pus；Rhizoma Ligustici, expelling wind and cold, removing damp and stopping pain；Radix Luffae, promoting blood circulation to remove obstruction in the collateral, heat-clearing and toxic substances removing；Radix Cynanchi Atrati, heat clearing away dissipates swollen, controls excess of the lung nasal obstruction.
Described solidifying cream base matter is mixed by the white vaseline of weight portion such as grade, lanoline, described solidifying cream base matter and Chinese drug-treated group
The mass ratio of compound is 0.9: 1.
1, by Herba Centipedae, Semen Crotonis Pulveratum, Fructus Tribuli, Flos Magnoliae, Herba Asari, Moschus, Spina Gleditsiae, Fructus Xanthii, the Radix Angelicae Dahuricae, Herba Ephedrae, Qiang
Work, Radix Platycodonis, Rhizoma Ligustici, Radix Luffae and Radix Cynanchi Atrati drying and crushing, be ground to 240 mesh, obtains medicated powder I.
2, white vaseline, lanoline Hybrid Heating are become thick paste, borneol and grinding to 240 mesh, add in thick paste and dissolve, then
Add medicated powder I and be in harmonious proportion uniformly, receive cream, obtain the Chinese medicinal ointment of described treatment sinusitis.
Embodiment 4
A kind of Chinese medicinal ointment treating sinusitis, is in harmonious proportion by Chinese medicine composition and solidifying cream base matter and is prepared from, wherein, described in
Drug composition mainly comprises the component of following weight portion: Herba Centipedae 10, Semen Crotonis Pulveratum 0.5, Fructus Tribuli 10, Flos Magnoliae 10, Herba Asari 3,
Moschus 0.5, Spina Gleditsiae 10, Fructus Xanthii 15, Borneolum Syntheticum 2, the Radix Angelicae Dahuricae 10, Herba Ephedrae 3, Rhizoma Et Radix Notopterygii 3, Radix Platycodonis 4, Rhizoma Ligustici 3, Radix Luffae 5 and white
Common vetch 3.On this basis, adding Rhizoma Chuanxiong 2 weight portion, Nodus Nelumbinis Rhizomatis 2 weight portion, it is high that compatibility controls nasal sinusitis profit nine orifices effect；Fructus Gleditsiae Abnormalis 0.3 weight
Amount part, eliminates the phlegm and has one's ideas straightened out, mass dissipating and swelling eliminating；Rhizoma Dioscoreae Nipponicae 2 weight portion, relaxing muscles and tendons to promote blood circulation, wind-expelling pain-stopping；Caulis Trachelospermi 2 weight portion, dispels the wind logical
Network, removing heat from blood is subsided a swelling；Rhizoma Bolbostematis 3 weight portion, detoxicating and resolving stagnation of pathogens, detumescence.
Clinical data:
1, the standard of curative effect evaluation judges with reference to " new Chinese medicine guideline of clinical investigations " relevant criterion:
Cure: clinical symptoms and sign all disappear, and nasal meatus disappears without purulence or glutinous purulent secretion, CT examination rhinosinusitis condition
Lose, further consultation thing recurrence after three months；
Effective: clinical symptoms and sign substantially alleviate, there is a little glutinous purulent secretion in nasal meatus, CT display sinus cavities is slight
Muddy；
Invalid: symptom and sign thing significant change.
Total effective rate=cure rate+obvious effective rate
2, therapeutic scheme:
Chinese medicinal ointment of the present invention is smeared and nasal cavity, smears 2-4 time every day, treat 5-7 days be a course for the treatment of, control continuously
Treat 1-3 the course for the treatment of.
3, therapeutic effect statistics:
Use described therapeutic scheme that 100 example sinusitis in patients are treated, and add up according to the standard of curative effect evaluation.
In 100 example clinical patients, at minimum 12 years old of age, maximum 68 years old, 38 years old mean age, wherein, suffer from the 56 of below sinusitis half a year
People, 28 people of ill more than 1 year.Through clinical treatment and statistics, 92 people cure, effective 6 examples, invalid 2 examples, cure rate 92%, always
Effective percentage 98%.
Although embodiment of the present invention are disclosed as above, but it is not restricted in description and embodiment listed
Using, it can be applied to various applicable the field of the invention completely, for those skilled in the art, and can be easily
Realizing other amendment, therefore under the general concept limited without departing substantially from claim and equivalency range, the present invention does not limit
In specific details.
Claims (7)
1. treat a Chinese medicinal ointment for sinusitis, Chinese medicine composition and solidifying cream base matter are in harmonious proportion and are prepared from, wherein, described Chinese medicine
Compositions mainly comprises the component of following weight portion:
Herba Centipedae 8-12, Semen Crotonis Pulveratum 0.3-0.7, Fructus Tribuli 8-12, Flos Magnoliae 8-12, Herba Asari 2-4, Moschus 0.4-0.6, Spina Gleditsiae
8-12, Fructus Xanthii 13-18, Borneolum Syntheticum 1-3 and Radix Angelicae Dahuricae 8-12.
2. the Chinese medicinal ointment treating sinusitis as claimed in claim 1, wherein, described Chinese medicine composition mainly comprises following weight
The component of part:
Herba Centipedae 10, Semen Crotonis Pulveratum 0.5, Fructus Tribuli 10, Flos Magnoliae 10, Herba Asari 3, Moschus 0.5, Spina Gleditsiae 10, Fructus Xanthii 15, Borneolum Syntheticum
2 and the Radix Angelicae Dahuricae 10.
3. the Chinese medicinal ointment treating sinusitis as claimed in claim 1, wherein, described solidifying cream base matter mainly includes waiting weight portion
At least one in white vaseline, lanoline and Oleum Sesami；Described solidifying cream base matter is 0.8-1.2 with the mass ratio of Chinese medicine composition
∶1。
4. the Chinese medicinal ointment treating sinusitis as claimed in claim 3, wherein, described Chinese medicine composition also includes following weight portion
Component:
Herba Ephedrae 2-4, Rhizoma Et Radix Notopterygii 2-4, Radix Platycodonis 3-5, Rhizoma Ligustici 2-4, Radix Luffae 4-6 and Radix Cynanchi Atrati 2-4.
5. the Chinese medicinal ointment treating sinusitis as claimed in claim 4, wherein, described Chinese medicine composition also includes following weight portion
Component:
Herba Ephedrae 3, Rhizoma Et Radix Notopterygii 3, Radix Platycodonis 4, Rhizoma Ligustici 3, Radix Luffae 5 and Radix Cynanchi Atrati 3.
6. a preparation method for the Chinese medicinal ointment for the treatment of sinusitis as claimed in claim 3, wherein, mainly includes following step
Rapid:
Step 6.1, Herba Centipedae, Semen Crotonis Pulveratum, Fructus Tribuli, Flos Magnoliae, Herba Asari, Moschus, Spina Gleditsiae, Fructus Xanthii and the Radix Angelicae Dahuricae are dried
Pulverize, be ground to more than 200 mesh, obtain medicated powder I；
Step 6.2, white vaseline, lanoline, Oleum Sesami Hybrid Heating are become thick paste, more than borneol and grinding to 200 mesh, add thick paste
Middle dissolving, is subsequently adding medicated powder I and is in harmonious proportion uniformly, receive cream, obtain the Chinese medicinal ointment of described treatment sinusitis.
7. a preparation method for the Chinese medicinal ointment for the treatment of sinusitis as claimed in claim 4, wherein, mainly includes following step
Rapid:
Step 7.1, by Herba Centipedae, Semen Crotonis Pulveratum, Fructus Tribuli, Flos Magnoliae, Herba Asari, Moschus, Spina Gleditsiae, Fructus Xanthii, the Radix Angelicae Dahuricae, Herba Ephedrae,
Rhizoma Et Radix Notopterygii, Radix Platycodonis, Rhizoma Ligustici, Radix Luffae and Radix Cynanchi Atrati drying and crushing, be ground to more than 200 mesh, obtains medicated powder II；
Step 7.2, white vaseline, lanoline, Oleum Sesami Hybrid Heating are become thick paste, more than borneol and grinding to 200 mesh, add thick paste
Middle dissolving, is subsequently adding medicated powder II and is in harmonious proportion uniformly, receive cream, obtain the Chinese medicinal ointment of described treatment sinusitis.
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Application publication date: 20161026 |