CN105106353A - Traditional Chinese medicine compound treating nyctalopia and preparation method - Google Patents

Traditional Chinese medicine compound treating nyctalopia and preparation method Download PDF

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CN105106353A
CN105106353A CN201510588403.7A CN201510588403A CN105106353A CN 105106353 A CN105106353 A CN 105106353A CN 201510588403 A CN201510588403 A CN 201510588403A CN 105106353 A CN105106353 A CN 105106353A
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radix
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herba
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不公告发明人
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Liu Shangan
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Liu Shangan
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Abstract

The invention discloses a traditional Chinese medicine compound treating nyctalopia and a preparation method. The traditional Chinese medicine compound treating nyctalopia is prepared from, by weight, 10-15 parts of radix codonopsis, 8-16 parts of white oaks, 6-13 parts of elsholtzia blanda, 9-15 parts of herbs of sessile skullcap, 7-12 parts of broomjutre sida herbs, 9-14 parts of flowers of official magnolia, 8-15 parts of clove branches, 6-12 parts of Japan clover herbs, 10-14 parts of tartarian buckwheat, 7-16 parts of potentilla discolor, 9-13 parts of cacumen biotae, 8-14 parts of quisqualis leaves, 6-15 parts of phyllanthus matsumurae hayata and 7-14 parts of litsea rotundifolia. The traditional Chinese medicine compound is remarkable in treatment effect, safe, free of toxic and side effects and low in treatment cost, and relapse of nyctalopia does not occur after nyctalopia is healed.

Description

A kind of Chinese medicine composition and method for making curing nyctalopia
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine composition and the method for making of curing nyctalopia.
Background technology
In ophthalmic diseases, nyctalopia is very common a kind of disease.Nyctalopia is also known as nyctalopia, night blindness.Patient's binocular outward appearance is normal, during every insufficient light at night, i.e. and fuzzy viewing, and daytime, eyesight was as usual.The traditional Chinese medical science is thought, nyctalopia is many because natural endowment is not enough or lose foster after being ill, so that deficiency of both the liver and kidney.Liver opening at eye, the pupil belongs to kidney, deficiency of the liver and kindey, and two orders lose supports, so nyctalopia.According to theory of Chinese medical science, the nyctalopia patient of deficiency of both the liver and kidney, should eat have nourishing the liver and kidney, nourishing the liver to improve visual acuity effect food and containing vitamin A than more rich food; Avoid and eat pungent irritable food, avoid very popular dry impairment of YIN, the food helping fire hot in nature, quit smoking and wine.Nyctalopia brings a lot of inconvenience to the life of patient especially evening.
Application publication number CN104825685A(application number 201510215449.4) Chinese patent literature disclose a kind of Chinese medicine for the treatment of nyctalopia, be made up of following raw material: Semen Celosiae, Semen Cassiae, Fructus Lycii, Flos Lonicerae, Flos Rosae Chinensis, Herba Phyllanthi Urinariae, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Flos Buddlejae, Flos Eriocauli, Caulis Akebiae, Faeces Vespertilionis, Indigo Naturalis, Ramulus Uncariae Cum Uncis, Radix Coriariae Sinicae, Semen Cuscutae, Rhizoma Atractylodis, Cortex Phellodendri, Herba Schizonepetae, Periostracum Cicadae, Herba Ocimi (Herba Ocimi Pilosi), Thalictrum omeiense W. T. Wang et S. H. Wang, Fructus Ligustri Lucidi, Poria cum Radix Pini, Semen sojae atricolor.Application publication number CN104274618A(application number 201310310079.3) Chinese patent literature disclose a kind of Chinese medicine formula for the treatment of nyctalopia, comprise following component: the thin block of Radix Dauci Sativae 50 grams, each 20 grams of Radix Puerariae, Pericarpium Granati, Lasiosphaera Seu Calvatia, Semen Gleditsiae, Herba Cistanches, Semen Cassiae, Herba Equiseti Hiemalis, Rhizoma Atractylodis, Folium Isatidis, each 10 grams of Flos Chrysanthemi Indici, Hepar Gallus domesticus 1 is secondary.Application publication number CN104208423A(application number 201410456731.7) Chinese patent literature disclose a kind of Chinese medicine for the treatment of nyctalopia, with 32 taste Chinese herbal medicine such as Radix Notoginseng, Radix Angelicae Sinensis, Cornu Cervi, Faeces Vespertilionis, Herba Equiseti Hiemalis, Periostracum Cicadae, Flos Chrysanthemi, Rhizomadioscoreae, Ba Ji, Herba Cistanches, the Rhizoma Atractylodis Macrocephalae, Fructus Jujubae, Fructus Broussonetiaes for raw material, be mixed according to certain weight proportion.
There is no the specific drug for the treatment of nyctalopia at present.Western medicine to supplement a large amount of vitamin A, cod-liver oil for oral administration or be main with vitamin A eye dripping.Western medicine curative effect is undesirable, is easy to recurrence.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine composition and the method for making of curing nyctalopia.The present invention is evident in efficacy, and safely, have no side effect, medical expense is low, non-relapse after healing.
Technical scheme of the present invention is:
Cure a Chinese medicine composition for nyctalopia, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Codonopsis 10-15, Involucrum Querci fabri 8-16, Herba Elsholtziae Blandae 6-13, Herba Scutellariae Sessilifoliae 9-15, Herba Sidae Rhombifoliae 7-12, Flos Magnoliae Officinalis 9-14, Caulis Caryophylli 8-15, Herba Kummerowiae Striatae 6-12, Radix Et Rhizoma Fagopyri Tatarici 10-14, Herba Potentillae Discoloris 7-16, Cacumen Platycladi 9-13, Folium Quisqualis 8-14, Herba Phyllanthi matsumuraes 6-15, Corii Cuon alpini Camphor tree 7-14.
Cure a Chinese medicine composition for nyctalopia, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Codonopsis 11-14, Involucrum Querci fabri 10-14, Herba Elsholtziae Blandae 8-11, Herba Scutellariae Sessilifoliae 11-13, Herba Sidae Rhombifoliae 9-11, Flos Magnoliae Officinalis 10-12, Caulis Caryophylli 11-14, Herba Kummerowiae Striatae 8-11, Radix Et Rhizoma Fagopyri Tatarici 11-13, Herba Potentillae Discoloris 9-14, Cacumen Platycladi 10-12, Folium Quisqualis 10-13, Herba Phyllanthi matsumuraes 9-13, Corii Cuon alpini Camphor tree 9-12.
Cure a Chinese medicine composition for nyctalopia, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Codonopsis 13, Involucrum Querci fabri 12, Herba Elsholtziae Blandae 9, Herba Scutellariae Sessilifoliae 12, Herba Sidae Rhombifoliae 10, Flos Magnoliae Officinalis 11, Caulis Caryophylli 12, Herba Kummerowiae Striatae 10, Radix Et Rhizoma Fagopyri Tatarici 12, Herba Potentillae Discoloris 13, Cacumen Platycladi 11, Folium Quisqualis 12, Herba Phyllanthi matsumuraes 11, Corii Cuon alpini Camphor tree 11.
Present invention also offers the preparation method Chinese medicine composition of aforementioned treatment nyctalopia being made pharmaceutically acceptable pill, granule, capsule and powder.
The preparation method of described pill is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, and fries 7-13 minute (preferably frying 10 minutes), takes out, cool, be ground into fine powder, cross 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine to mix thoroughly, the amount of yellow wine is the amount of the preferred yellow wine of 1/6-1/4(of Radix Et Rhizoma Fagopyri Tatarici weight is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight), dry in the air 5-8 hour (preferably drying in the air 7 hours), puts into 55-65 DEG C of baking oven (preferably putting into 60 DEG C of baking ovens), dry 15 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50-80 mesh sieve (preferred mistake 70 mesh sieve), put into 55 DEG C of baking ovens, dry 6-10 hour (preferably drying 8 hours), take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, with water pill, make the pill that particle diameter is 3mm, dry, to obtain final product.
The preparation method of described granule is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, and fries 7-13 minute (preferably frying 10 minutes), takes out, cool, be ground into fine powder, cross 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine to mix thoroughly, the amount of yellow wine is the amount of the preferred yellow wine of 1/6-1/4(of Radix Et Rhizoma Fagopyri Tatarici weight is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight), dry in the air 5-8 hour (preferably drying in the air 7 hours), puts into 55-65 DEG C of baking oven (preferably putting into 60 DEG C of baking ovens), dry 15 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50-80 mesh sieve (preferred mistake 70 mesh sieve), put into 55 DEG C of baking ovens, dry 6-10 hour (preferably drying 8 hours), take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, heavy-duty tabletting press is pressed into the embryo sheet that diameter is 20mm, then is broken into granule, to obtain final product.
The preparation method of described capsule is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, and fries 7-13 minute (preferably frying 10 minutes), takes out, cool, be ground into fine powder, cross 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine to mix thoroughly, the amount of yellow wine is the amount of the preferred yellow wine of 1/6-1/4(of Radix Et Rhizoma Fagopyri Tatarici weight is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight), dry in the air 5-8 hour (preferably drying in the air 7 hours), puts into 55-65 DEG C of baking oven (preferably putting into 60 DEG C of baking ovens), dry 15 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50-80 mesh sieve (preferred mistake 70 mesh sieve), put into 55 DEG C of baking ovens, dry 6-10 hour (preferably drying 8 hours), take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, in incapsulating, medicated powder 0.32g is housed in every capsules, obtains final product.
The preparation method of described powder is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, and fries 7-13 minute (preferably frying 10 minutes), takes out, cool, be ground into fine powder, cross 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine to mix thoroughly, the amount of yellow wine is the amount of the preferred yellow wine of 1/6-1/4(of Radix Et Rhizoma Fagopyri Tatarici weight is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight), dry in the air 5-8 hour (preferably drying in the air 7 hours), puts into 55-65 DEG C of baking oven (preferably putting into 60 DEG C of baking ovens), dry 15 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50-80 mesh sieve (preferred mistake 70 mesh sieve), put into 55 DEG C of baking ovens, dry 6-10 hour (preferably drying 8 hours), take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, with 5g often bag subpackage, sterile packaged, to obtain final product.
The Chinese medicine composition scientific formula for the treatment of nyctalopia provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:
, have no side effect 1, safely;
2, medical expense is low, non-relapse after healing;
3, medicine source is extensive, and cheap;
4, there is effect of spleen invigorating lung benefiting, QI invigorating improving eyesight, clearing away heat and cooling blood, liver heat removing and eyesight improving, inducing diuresis and reducing edema, dissipating depression of QI dampness dissipating, QI regulating circulation of qi promoting, evident in efficacy.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1cure a Chinese medicine composition for nyctalopia, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Codonopsis 10 parts, Involucrum Querci fabri 8 parts, Herba Elsholtziae Blandae 6 parts, Herba Scutellariae Sessilifoliae 9 parts, Herba Sidae Rhombifoliae 7 parts, Flos Magnoliae Officinalis 9 parts, Caulis Caryophylli 8 parts, Herba Kummerowiae Striatae 6 parts, Radix Et Rhizoma Fagopyri Tatarici 10 parts, Herba Potentillae Discoloris 7 parts, Cacumen Platycladi 9 parts, Folium Quisqualis 8 parts, Herba Phyllanthi matsumuraes 6 parts, Corii Cuon alpini Camphor tree 7 parts.
The preparation method of the Chinese medicine composition composition powders of above-mentioned treatment nyctalopia is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, fries 7 minutes, takes out, cools, be ground into fine powder, crosses 180 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine and mix thoroughly, the amount of yellow wine is 1/6 of Radix Et Rhizoma Fagopyri Tatarici weight, dries in the air 5 hours, puts into 55 DEG C of baking ovens, dries 15 hours, takes out, is ground into fine powder, crosses 180 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 180 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50 mesh sieves, put into 55 DEG C of baking ovens, dry 6 hours, take out, be ground into fine powder, cross 180 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, with 5g often bag subpackage, sterile packaged, to obtain final product.
The instructions of taking that gained of the present invention cures the Chinese medicine composition composition powders of nyctalopia is: oral, one day twice, each 5g, boiled water was taken after mixing it with water.
embodiment 2cure a Chinese medicine composition for nyctalopia, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Codonopsis 15 parts, Involucrum Querci fabri 16 parts, Herba Elsholtziae Blandae 13 parts, Herba Scutellariae Sessilifoliae 15 parts, Herba Sidae Rhombifoliae 12 parts, Flos Magnoliae Officinalis 14 parts, Caulis Caryophylli 15 parts, Herba Kummerowiae Striatae 12 parts, Radix Et Rhizoma Fagopyri Tatarici 14 parts, Herba Potentillae Discoloris 16 parts, Cacumen Platycladi 13 parts, Folium Quisqualis 14 parts, Herba Phyllanthi matsumuraes 15 parts, Corii Cuon alpini Camphor tree 14 parts.
The preparation method of the Chinese medicine composition pill of above-mentioned treatment nyctalopia is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, fries 10 minutes, takes out, cools, be ground into fine powder, crosses 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine and mix thoroughly, the amount of yellow wine is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight, dries in the air 7 hours, puts into 60 DEG C of baking ovens, dries 15 hours, takes out, is ground into fine powder, crosses 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 70 mesh sieves, put into 55 DEG C of baking ovens, dry 8 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, with water pill, make the pill that particle diameter is 3mm, dry, to obtain final product.
model case one:gold XX, man, 35 years old.Main suit: suffer from nyctalopia more than 7 years.Before 7 years, patient appears at daytime and can see thing, once seeing that thing is unclear to night.Nyctalopia is diagnosed as to examination in hospital.Once took multi-medicament treatment, and failed to cure.Then medical.Patient at night visual deterioration, blurred vision.Take the Chinese medicine composition pill that the present embodiment gained cures nyctalopia, three times on the one, each 5 balls, warm water takes.Take 2 weeks, night, vision took a turn for the better.Continue to take two weeks, vision restoration is normal.Follow up a case by regular visits to and do not recur so far.
embodiment 3cure a Chinese medicine composition for nyctalopia, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Codonopsis 11 parts, Involucrum Querci fabri 10 parts, Herba Elsholtziae Blandae 8 parts, Herba Scutellariae Sessilifoliae 11 parts, Herba Sidae Rhombifoliae 9 parts, Flos Magnoliae Officinalis 10 parts, Caulis Caryophylli 11 parts, Herba Kummerowiae Striatae 8 parts, Radix Et Rhizoma Fagopyri Tatarici 11 parts, Herba Potentillae Discoloris 9 parts, Cacumen Platycladi 10 parts, Folium Quisqualis 10 parts, Herba Phyllanthi matsumuraes 9 parts, Corii Cuon alpini Camphor tree 9 parts.
The preparation method of the Chinese medicinal composition granules of above-mentioned treatment nyctalopia is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, fries 10 minutes, takes out, cools, be ground into fine powder, crosses 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine and mix thoroughly, the amount of yellow wine is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight, dries in the air 7 hours, puts into 60 DEG C of baking ovens, dries 15 hours, takes out, is ground into fine powder, crosses 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 70 mesh sieves, put into 55 DEG C of baking ovens, dry 8 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, heavy-duty tabletting press is pressed into the embryo sheet that diameter is 20mm, then is broken into granule, to obtain final product.
model case two:xu XX, female, 30 years old.Main suit: suffer from nyctalopia more than 10 years.Before 10 years, patient occurs not having evening lamp to cannot see thing, has lamp visible.Nyctalopia is diagnosed as to examination in hospital.Took multi-medicament, without being clearly better.Then medical.Examine and see that patient's eyes are roughly normal for incubation period, amplitude reduces, and RPE becomes retina to disappear.Take the Chinese medicinal composition granules that the present embodiment gained cures nyctalopia, three times on the one, each 10g, boiled water is taken after mixing it with water.Take 2 weeks, night, vision was obviously improved.Continue to take two weeks, vision restoration is normal.Follow up a case by regular visits to and do not recur so far.
embodiment 4cure a Chinese medicine composition for nyctalopia, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Codonopsis 14 parts, Involucrum Querci fabri 14 parts, Herba Elsholtziae Blandae 11 parts, Herba Scutellariae Sessilifoliae 13 parts, Herba Sidae Rhombifoliae 11 parts, Flos Magnoliae Officinalis 12 parts, Caulis Caryophylli 14 parts, Herba Kummerowiae Striatae 11 parts, Radix Et Rhizoma Fagopyri Tatarici 13 parts, Herba Potentillae Discoloris 14 parts, Cacumen Platycladi 12 parts, Folium Quisqualis 13 parts, Herba Phyllanthi matsumuraes 13 parts, Corii Cuon alpini Camphor tree 12 parts.
The preparation method of the Chinese medicinal composition capsules agent of above-mentioned treatment nyctalopia is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, fries 10 minutes, takes out, cools, be ground into fine powder, crosses 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine and mix thoroughly, the amount of yellow wine is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight, dries in the air 7 hours, puts into 60 DEG C of baking ovens, dries 15 hours, takes out, is ground into fine powder, crosses 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 70 mesh sieves, put into 55 DEG C of baking ovens, dry 8 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, in incapsulating, medicated powder 0.32g is housed in every capsules, obtains final product.
model case three:liu XX, man, 38 years old.Main suit: suffer from nyctalopia more than 15 years.Before 15 years, patient finds suffers from nyctalopia.Once the medicine such as long-term taking cod-liver oil, LIUWEI MINGMU WAN, vitamin, Radix Salviae Miltiorrhizae Tabellae, without taking a turn for the better.Listen friend to introduce, the present invention treats nyctalopia Be very effective, decides and makes a try.Take the Chinese medicinal composition capsules agent that the present embodiment gained cures nyctalopia, three times on the one, each 2, warm water takes.Take surrounding continuously, vision restoration is normal.Follow up a case by regular visits to and do not recur so far.
embodiment 5cure a Chinese medicine composition for nyctalopia, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Codonopsis 13 parts, Involucrum Querci fabri 12 parts, Herba Elsholtziae Blandae 9 parts, Herba Scutellariae Sessilifoliae 12 parts, Herba Sidae Rhombifoliae 10 parts, Flos Magnoliae Officinalis 11 parts, Caulis Caryophylli 12 parts, Herba Kummerowiae Striatae 10 parts, Radix Et Rhizoma Fagopyri Tatarici 12 parts, Herba Potentillae Discoloris 13 parts, Cacumen Platycladi 11 parts, Folium Quisqualis 12 parts, Herba Phyllanthi matsumuraes 11 parts, Corii Cuon alpini Camphor tree 11 parts.
The preparation method of the Chinese medicine composition composition powders of above-mentioned treatment nyctalopia is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, fries 10 minutes, takes out, cools, be ground into fine powder, crosses 180 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine and mix thoroughly, the amount of yellow wine is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight, dries in the air 7 hours, puts into 60 DEG C of baking ovens, dries 15 hours, takes out, is ground into fine powder, crosses 180 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 180 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 70 mesh sieves, put into 55 DEG C of baking ovens, dry 8 hours, take out, be ground into fine powder, cross 180 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, with 5g often bag subpackage, sterile packaged, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Codonopsis: base is former: be the dry root of Campanulaceae Radix Codonopsis, element flower Radix Codonopsis or radix codonpsis tangshen etc.The property of medicine: sweet, flat.Return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Involucrum Querci fabri: base is former: for Fagaceae white oak is with the fruit of insect gall, involucre or root.The property of medicine: bitter; Puckery; Property is put down.Function cures mainly: removing food stagnancy of regulating the flow of vital energy; Improving eyesight is detoxified.Main infantile malnutrition; Hernia; Have loose bowels; Dysentery; Acute catarrhal conjunctivitis swelling pain; Furuncle.
Herba Elsholtziae Blandae: base is former: be the herb of labiate Elsholtzia blanda.The property of medicine: bitter in the mouth; Pungent; Property is put down.Function cures mainly: heat clearing away; Dampness removing; Removing toxic substances.Main cold, fever; Sensible heat dysentery; Jaundice; Dysuria; Foot a word used for translation is rotten itches; Burn.
Herba Scutellariae Sessilifoliae: base is former: be the herb of labiate stockless Radix Scutellariae.The property of medicine: bitter in the mouth; Pungent; Cool in nature.Function cures mainly: dispelling wind to relieve the exterior syndrome; Liver heat removing and eyesight improving.Main headache due to common cold; Wind heat blurred vision.
Herba Sidae Rhombifoliae: base is former: for Malvaceae plant carries on the back the herb of Radix sidae acutae in vain.The property of medicine: sweet in the mouth; Pungent; Cool.GUIXIN, liver, lung, large intestine, small intestine meridian.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.The high heat of main flu; Laryngopharynx swelling and pain; Damp-heat dysentery; Jaundice; Leukorrhagia; Stranguria; Rheumatism flaccidity is weak; Dizzy; Labor volume is weak; Hemorrhoidal bleeding; Carbuncle furuncle.
Flos Magnoliae Officinalis: base is former: be the alabastrum of Magnoliacea plant Cortex Magnoliae Officinalis or Mount Lushan Cortex Magnoliae Officinalis.The property of medicine: pungent; Micro-hardship; Warm in nature.Return spleen, stomach, lung meridian.Function cures mainly: promoting the circulation of QI to alleviate the stagnation in middle-JIAO; Dissipating depression of QI removing dampness.Main stagnation of liver-QI and stomach-QI; Breast gastral cavity feeling of distension and oppression; Inappetence; Poor appetite; The card such as cold cough is coughed, and dysphoria with smothery sensation is palpitated with fear, gastric heat.
Caulis Caryophylli: base is former: be the branch of plant clove of myrtaceae.The property of medicine: acrid in the mouth; Property is put down.Return spleen, stomach warp.Function cures mainly: cold expelling of regulating the flow of vital energy; Warming middle-JIAO to stop diarrhea.Main distension and fullness in the abdomen; Feel sick; Have loose bowels empty sliding; Indigestion.
Herba Kummerowiae Striatae: base is former: be the herb of leguminous plant Herba Kummerowiae Striatae and perpendicular hair chicken.The property of medicine: sweet; Pungent; Micro-hardship; Property is put down.Return liver, spleen, lung, kidney channel.Function cures mainly: heat-clearing and toxic substances removing, invigorating spleen to remove dampness, promoting blood circulation and hemostasis.Main cold, fever, heat-damp in summer is vomited and diarrhoea, jaundice, carbuncle furuncle, dysentery, infantile malnutrition, stranguria with blood, spitting of blood, epistaxis, traumatic injury, leucorrhea with red and white discharge.
Radix Et Rhizoma Fagopyri Tatarici: base is former: be the root and rhizome of polygonaceae plant Radix Et Rhizoma Fagopyri Tatarici.The property of medicine: sweet; Property is put down; Mild toxicity.Return spleen, stomach, large intestine channel.Function cures mainly: spleen invigorating row is stagnant, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling.Main epigastric distending pain, dyspepsia, dysentery, lumbago and skelalgia, traumatic injury, carbuncle malignant boil, lyssodexis.
Herba Potentillae Discoloris: base is former: be the whole herb with root of Flos Rosae Multiflorae kind of plant Herba Potentillae Discoloris.The property of medicine: sweet; Bitter; Flat.Function cures mainly: heat-clearing and toxic substances removing; Cooling blood for hemostasis.Main lung-heat cough with asthma; Dysentery; Malaria; Hemoptysis; Have blood in stool; Metrorrhagia; Carbuncle sore tumefacting virus; Skin ulcer tinea tuberculosis.
Cacumen Platycladi: base is former: be branch top and the leaf of Cupressaceae plant Cacumen Platycladi.The property of medicine: bitter; Puckery; Cold nature.Return lung, liver, large intestine channel.Function cures mainly: cooling blood for hemostasis; Eliminating phlegm and stopping cough; Wind-damp dispelling; Loose toxic swelling.Cure mainly spitting of blood; Spit blood; Epistaxis; Hematuria; Dysentery; Discharging fresh blood stool; Metrorrhagia is more than; Cough with copious phlegm; Rheumatic arthralgia; Erysipelas; Mumps, scalds.
Folium Quisqualis: base is former: the leaf of Combretum Racemosum plant Fructus Quisqualis.The property of medicine: acrid in the mouth; Property is put down.Return spleen, stomach warp.Function cures mainly: regulating qi-flowing for strengthening spleen; Parasite killing detoxifies.Main distension and fullness in the abdomen; Infantile malnutrition; Malnutrition due to parasitic infestation; Furuncle ulcer.
Herba Phyllanthi matsumuraes: base is former: be the herb of Euphorbiaceae value thing Herba Phyllanthi matsumuraes.The property of medicine: bitter in the mouth; Cold in nature.Return liver, stomach warp.Function cures mainly: clearing away heat-damp and promoting diuresis; Liver heat removing and eyesight improving.Main jaundice; Dysentery; Have loose bowels; Edema; Gonorrhea; Infantile malnutrition; Conjunctival congestion and swelling pain; Hemorrhoid; Venom.
Corii Cuon alpini Camphor tree: base is former: be root and the bark of canella Corii Cuon alpini Camphor tree.The property of medicine: pungent; Temperature.Return liver, stomach, spleen, kidney channel.Function cures mainly: promoting flow of QI and blood pain relieving; Wind-damp dispelling.Main stomachache; Stomachache; Dysentery; Diarrhoea; Dysmenorrhea; Rheumatic arthralgia; Traumatic injury.
test example 1gained of the present invention cures the clinical practice of the Chinese medicine composition (embodiment 5) of nyctalopia: in January, 2012 in December ,-2013, screen 360 routine nyctalopia patients in 3 hospitals and carry out clinical observation.Wherein man 195 example, female 165 example; The oldest 63 years old, minimum 16 years old of age.Be divided into experimental group 180 example at random, matched group 180 example.The equal no significant difference of clinical data (P > 0.05) such as sex, age, the course of disease and symptom and sign between two groups of patients.
Experimental group takes products obtained therefrom of the present invention, instructions of taking: oral, one day twice, each 5g, and boiled water is taken after mixing it with water, and within seven days, is a course for the treatment of.Matched group uses the Drug therapys such as cod-liver oil, three taste cod-liver oil emulsions, LIUWEI MINGMU WAN, within seven days, is a course for the treatment of.Therapeutic evaluation is carried out after two groups of cases all treat four courses for the treatment of.
Curative effect situation criterion: cure: clinical symptoms, sign disappear; Effective: clinical symptoms, sign are clearly better; Invalid: clinical symptoms, sign are not improved.Total effectively comprising cures and takes a turn for the better.Result is as shown in table 1.
Table 1: gained of the present invention cures the Chinese medicine composition compliance test result of nyctalopia
Therapeutic effect: experimental group cures 158 examples (87.78%), effective 19 examples (10.55%), invalid 3 examples (1.67%), total effective rate 98.33%.Matched group cures 70 examples (38.89%), effective 75 examples (41.67%), and invalid 35 examples (19.44%), total effective rate is 80.56%.Experimental group successful is better than matched group.
The present invention is primary raw material medicine with Radix Codonopsis, Involucrum Querci fabri, Herba Elsholtziae Blandae and Herba Scutellariae Sessilifoliae etc., makes the Chinese medicine composition of curing nyctalopia.Radix Codonopsis invigorating the spleen and replenishing QI in side, spleen invigorating lung benefiting.Involucrum Querci fabri is regulated the flow of vital energy removing food stagnancy; Improving eyesight is detoxified.Herba Elsholtziae Blandae heat clearing away; Dampness removing; Removing toxic substances.Herba Scutellariae Sessilifoliae dispelling wind to relieve the exterior syndrome; Liver heat removing and eyesight improving.Herba Sidae Rhombifoliae clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Flos Magnoliae Officinalis promoting the circulation of QI to alleviate the stagnation in middle-JIAO; Dissipating depression of QI removing dampness.Caulis Caryophylli is regulated the flow of vital energy cold expelling; Warming middle-JIAO to stop diarrhea.Herba Kummerowiae Striatae heat-clearing and toxic substances removing, invigorating spleen to remove dampness, promoting blood circulation and hemostasis.Radix Et Rhizoma Fagopyri Tatarici spleen invigorating row is stagnant, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling.Herba Potentillae Discoloris heat-clearing and toxic substances removing; Cooling blood for hemostasis.Cacumen Platycladi cooling blood for hemostasis; Eliminating phlegm and stopping cough; Wind-damp dispelling; Loose toxic swelling.Folium Quisqualis regulating qi-flowing for strengthening spleen; Parasite killing detoxifies.Herba Phyllanthi matsumuraes clearing away heat-damp and promoting diuresis; Liver heat removing and eyesight improving.The pain relieving of Corii Cuon alpini Camphor tree promoting flow of QI and blood; Wind-damp dispelling.Many medicines share, and mutually coordinate, and play the effect of spleen invigorating lung benefiting, QI invigorating improving eyesight, clearing away heat and cooling blood, liver heat removing and eyesight improving, inducing diuresis and reducing edema, dissipating depression of QI dampness dissipating, QI regulating circulation of qi promoting altogether, evident in efficacy.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. cure a Chinese medicine composition for nyctalopia, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Codonopsis 10-15, Involucrum Querci fabri 8-16, Herba Elsholtziae Blandae 6-13, Herba Scutellariae Sessilifoliae 9-15, Herba Sidae Rhombifoliae 7-12, Flos Magnoliae Officinalis 9-14, Caulis Caryophylli 8-15, Herba Kummerowiae Striatae 6-12, Radix Et Rhizoma Fagopyri Tatarici 10-14, Herba Potentillae Discoloris 7-16, Cacumen Platycladi 9-13, Folium Quisqualis 8-14, Herba Phyllanthi matsumuraes 6-15, Corii Cuon alpini Camphor tree 7-14.
2. Chinese medicine composition of curing nyctalopia as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Codonopsis 11-14, Involucrum Querci fabri 10-14, Herba Elsholtziae Blandae 8-11, Herba Scutellariae Sessilifoliae 11-13, Herba Sidae Rhombifoliae 9-11, Flos Magnoliae Officinalis 10-12, Caulis Caryophylli 11-14, Herba Kummerowiae Striatae 8-11, Radix Et Rhizoma Fagopyri Tatarici 11-13, Herba Potentillae Discoloris 9-14, Cacumen Platycladi 10-12, Folium Quisqualis 10-13, Herba Phyllanthi matsumuraes 9-13, Corii Cuon alpini Camphor tree 9-12.
3. Chinese medicine composition of curing nyctalopia as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Codonopsis 13, Involucrum Querci fabri 12, Herba Elsholtziae Blandae 9, Herba Scutellariae Sessilifoliae 12, Herba Sidae Rhombifoliae 10, Flos Magnoliae Officinalis 11, Caulis Caryophylli 12, Herba Kummerowiae Striatae 10, Radix Et Rhizoma Fagopyri Tatarici 12, Herba Potentillae Discoloris 13, Cacumen Platycladi 11, Folium Quisqualis 12, Herba Phyllanthi matsumuraes 11, Corii Cuon alpini Camphor tree 11.
4. the Chinese medicine composition of the treatment nyctalopia as described in as arbitrary in claims 1 to 3, it is characterized in that, the prescription of this treatment nyctalopia is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, and fries 7-13 minute (preferably frying 10 minutes), takes out, cool, be ground into fine powder, cross 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine to mix thoroughly, the amount of yellow wine is the amount of the preferred yellow wine of 1/6-1/4(of Radix Et Rhizoma Fagopyri Tatarici weight is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight), dry in the air 5-8 hour (preferably drying in the air 7 hours), puts into 55-65 DEG C of baking oven (preferably putting into 60 DEG C of baking ovens), dry 15 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50-80 mesh sieve (preferred mistake 70 mesh sieve), put into 55 DEG C of baking ovens, dry 6-10 hour (preferably drying 8 hours), take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, with water pill, make the pill that particle diameter is 3mm, dry, to obtain final product.
5. the Chinese medicine composition of the treatment nyctalopia as described in as arbitrary in claims 1 to 3, it is characterized in that, the prescription of this treatment nyctalopia is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, and fries 7-13 minute (preferably frying 10 minutes), takes out, cool, be ground into fine powder, cross 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine to mix thoroughly, the amount of yellow wine is the amount of the preferred yellow wine of 1/6-1/4(of Radix Et Rhizoma Fagopyri Tatarici weight is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight), dry in the air 5-8 hour (preferably drying in the air 7 hours), puts into 55-65 DEG C of baking oven (preferably putting into 60 DEG C of baking ovens), dry 15 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50-80 mesh sieve (preferred mistake 70 mesh sieve), put into 55 DEG C of baking ovens, dry 6-10 hour (preferably drying 8 hours), take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, heavy-duty tabletting press is pressed into the embryo sheet that diameter is 20mm, then is broken into granule, to obtain final product.
6. the Chinese medicine composition of the treatment nyctalopia as described in as arbitrary in claims 1 to 3, it is characterized in that, the prescription of this treatment nyctalopia is made pharmaceutically acceptable capsule, and the preparation method of described capsule is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, and fries 7-13 minute (preferably frying 10 minutes), takes out, cool, be ground into fine powder, cross 140 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine to mix thoroughly, the amount of yellow wine is the amount of the preferred yellow wine of 1/6-1/4(of Radix Et Rhizoma Fagopyri Tatarici weight is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight), dry in the air 5-8 hour (preferably drying in the air 7 hours), puts into 55-65 DEG C of baking oven (preferably putting into 60 DEG C of baking ovens), dry 15 hours, take out, be ground into fine powder, cross 140 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 140 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50-80 mesh sieve (preferred mistake 70 mesh sieve), put into 55 DEG C of baking ovens, dry 6-10 hour (preferably drying 8 hours), take out, be ground into fine powder, cross 140 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, in incapsulating, medicated powder 0.32g is housed in every capsules, obtains final product.
7. the Chinese medicine composition of the treatment nyctalopia as described in as arbitrary in claims 1 to 3, it is characterized in that, the prescription of this treatment nyctalopia is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) Flos Magnoliae Officinalis is put into pot, slow fire heats, and constantly stir-fries, and fries 7-13 minute, takes out, cools, be ground into fine powder, crosses 180 mesh sieves;
(2) by Radix Et Rhizoma Fagopyri Tatarici pulverization, cross 120 mesh sieves, add yellow wine and mix thoroughly, the amount of yellow wine is the 1/6-1/4 of Radix Et Rhizoma Fagopyri Tatarici weight, dry in the air 5-8 hour, puts into 55-65 DEG C of baking oven (preferably putting into 60 DEG C of baking ovens), dry 15 hours, take out, be ground into fine powder, cross 180 mesh sieves;
(3) by Cacumen Platycladi and Folium Quisqualis mixing, dry, grind to the powder altogether, cross 180 mesh sieves;
(4) by all the other the 10 taste crude drug mixing except Flos Magnoliae Officinalis, Radix Et Rhizoma Fagopyri Tatarici, Cacumen Platycladi and Folium Quisqualis, grind coarser powder altogether, cross 50-80 mesh sieve (preferred mistake 70 mesh sieve), put into 55 DEG C of baking ovens, dry 6-10 hour (preferably drying 8 hours), take out, be ground into fine powder, cross 180 mesh sieves;
(5) step (1), step (2), step (3) and step (4) gained are mixed, stir, with 5g often bag subpackage, sterile packaged, to obtain final product.
8. the preparation method curing the Chinese medicine composition composition powders of nyctalopia as claimed in claim 6, is characterized in that, select stir-fry 10 minutes in step (1).
9. the preparation method curing the Chinese medicine composition composition powders of nyctalopia as claimed in claim 6, is characterized in that, in step (2), the amount of yellow wine is 1/5 of Radix Et Rhizoma Fagopyri Tatarici weight.
10. the preparation method curing the Chinese medicine composition composition powders of nyctalopia as claimed in claim 6, is characterized in that, dry in the air 7 hours in step (2).
CN201510588403.7A 2015-09-16 2015-09-16 Traditional Chinese medicine compound treating nyctalopia and preparation method Pending CN105106353A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102793848A (en) * 2012-09-07 2012-11-28 黄平县润发药业农民专业合作社 Traditional Chinese medicine powder for treating night blindness

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102793848A (en) * 2012-09-07 2012-11-28 黄平县润发药业农民专业合作社 Traditional Chinese medicine powder for treating night blindness

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Title
叶任高等: "《中医临证指南》", 31 December 2002, 人民卫生出版社 *
梁凤鸣等: ""雀目"古医籍论述", 《中国中医眼科杂志》 *

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