CN105101994B - 用于口服脱敏的花生制剂的制备 - Google Patents

用于口服脱敏的花生制剂的制备 Download PDF

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Publication number
CN105101994B
CN105101994B CN201480013792.4A CN201480013792A CN105101994B CN 105101994 B CN105101994 B CN 105101994B CN 201480013792 A CN201480013792 A CN 201480013792A CN 105101994 B CN105101994 B CN 105101994B
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CN
China
Prior art keywords
peanut
ara
protein
peanut flour
flour
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Active
Application number
CN201480013792.4A
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English (en)
Chinese (zh)
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CN105101994A (zh
Inventor
B·瓦尔泽
H·V·拉夫
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Societe des Produits Nestle SA
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Aimmune Therapeutics Inc
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Application filed by Aimmune Therapeutics Inc filed Critical Aimmune Therapeutics Inc
Priority to CN201811093370.9A priority Critical patent/CN109125283A/zh
Publication of CN105101994A publication Critical patent/CN105101994A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201480013792.4A 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备 Active CN105101994B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811093370.9A CN109125283A (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361784964P 2013-03-14 2013-03-14
US61/784,964 2013-03-14
PCT/US2014/024401 WO2014159607A1 (en) 2013-03-14 2014-03-12 Manufacture of peanut formulations for oral desensitization

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201811093370.9A Division CN109125283A (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备

Publications (2)

Publication Number Publication Date
CN105101994A CN105101994A (zh) 2015-11-25
CN105101994B true CN105101994B (zh) 2018-10-12

Family

ID=51528061

Family Applications (2)

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CN201480013792.4A Active CN105101994B (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备
CN201811093370.9A Pending CN109125283A (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201811093370.9A Pending CN109125283A (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备

Country Status (19)

Country Link
US (5) US9198869B2 (https=)
EP (3) EP2968529B1 (https=)
JP (3) JP6752140B2 (https=)
CN (2) CN105101994B (https=)
AU (5) AU2014240404B2 (https=)
BR (1) BR112015021756B1 (https=)
CA (1) CA2903229A1 (https=)
DK (2) DK3482771T3 (https=)
ES (2) ES2940686T3 (https=)
FI (2) FI3482771T3 (https=)
FR (1) FR23C1026I2 (https=)
HU (1) HUE051831T2 (https=)
MX (1) MX2015010315A (https=)
NL (1) NL301236I2 (https=)
NO (1) NO2023027I1 (https=)
PL (1) PL2968529T3 (https=)
PT (1) PT2968529T (https=)
SI (1) SI2968529T1 (https=)
WO (1) WO2014159607A1 (https=)

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US9492535B2 (en) 2013-03-14 2016-11-15 Aimmune Therapeutics, Inc. Peanut formulations and uses thereof
AU2015306683B2 (en) 2014-08-25 2021-11-25 Societe Des Produits Nestle S.A. Egg protein formulations and methods of manufacture thereof
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
US11452774B2 (en) 2015-02-20 2022-09-27 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10149904B2 (en) 2015-02-20 2018-12-11 The Board Of Trusteees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
MA41558B1 (fr) 2015-02-20 2023-02-28 Univ Leland Stanford Junior Compositions d'allergènes mélangés et leurs procédés d'utilisation
US10143742B2 (en) 2015-02-20 2018-12-04 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10166286B2 (en) 2015-02-20 2019-01-01 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
TW201709926A (zh) * 2015-04-23 2017-03-16 賽諾菲公司 用於舌下投藥之吡喃葡萄糖基脂ａ及過敏原調配物
US10856567B2 (en) 2016-07-22 2020-12-08 Kari Brown Baby food products containing allergenic proteins and methods of delivering same
KR102609841B1 (ko) * 2016-12-05 2023-12-06 리액타 바이오테크 리미티드 경구 식품 유발시험 식사 제제
EP3568027A4 (en) * 2017-01-13 2020-11-11 Aimmune Therapeutics, Inc. WALNUT FLOUR MANUFACTURING PROCESSES AND FORMULATIONS FOR ORAL IMMUNOTHERAPY
AU2017279647B2 (en) 2017-02-15 2022-05-26 Euroimmun Medizinische Labordiagnostika Ag An improved assay for the diagnosis of peanut allergy
NZ760884A (en) 2017-07-18 2023-05-26 Nestle Sa Methods for making mixed allergen compositions
JP7498661B2 (ja) 2017-11-02 2024-06-12 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 経口免疫療法の方法
GB201718342D0 (en) * 2017-11-06 2017-12-20 Cambridge Allergy Ltd Allergenic protein formulations for immunotherapy
CA3087792A1 (en) 2018-01-16 2019-07-25 Tel Hashomer Medical Research Infrastructure And Services Ltd. Treatment and prevention of seed allergies
US11406563B2 (en) 2018-07-27 2022-08-09 Société des Produits Nestlé S.A. Oral immunotherapy unit dose dispensing systems and methods
WO2020037151A1 (en) 2018-08-16 2020-02-20 Aimmune Therapeutics, Inc. Peanut oral immunotherapy with maintenance dose
JP7659494B2 (ja) * 2018-12-17 2025-04-09 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 卵に対する経口免疫療法のための製剤、製造方法、及び卵アレルギーの治療
CA3123605A1 (en) * 2018-12-20 2020-06-25 Aimmune Therapeutics, Inc. Peanut oral immunotherapy dosing schedule for missed doses
CN113507844A (zh) 2019-01-23 2021-10-15 前品牌股份有限公司 制备混合型过敏原组合物的方法
EP3965815A4 (en) 2019-05-10 2023-05-31 Société des Produits Nestlé S.A. METHOD OF IMPROVING THE QUALITY OF LIFE IN A PEANUT ALLERGY PATIENT
ES3038192T3 (en) * 2019-08-08 2025-10-10 Evonik Operations Gmbh Method of preparing a solid dosage form and a lubricant
BR112022009664A2 (pt) * 2019-11-20 2022-08-16 Nestle Sa Métodos e sistemas para gerenciamento de distribuição e tratamento de um fármaco oral de imunoterapia para alergia a alimentos
CA3162040A1 (en) * 2019-12-23 2021-07-01 Bronwyn POLLOCK Pharmaceutical compositions
BR112022026945A2 (pt) 2020-07-01 2023-03-07 Nestle Sa Determinação de equipe médica para imunoterapia oral
EP4274609A1 (en) 2021-01-08 2023-11-15 Regeneron Pharmaceuticals, Inc. Methods for treating peanut allergy and enhancing peanut allergen-specific immunotherapy by administering an il-4r antagonist
CN119365211A (zh) 2022-04-11 2025-01-24 爱尔开-阿贝优公司 花生过敏原组合物

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US9492535B2 (en) * 2013-03-14 2016-11-15 Aimmune Therapeutics, Inc. Peanut formulations and uses thereof
AU2015306683B2 (en) 2014-08-25 2021-11-25 Societe Des Produits Nestle S.A. Egg protein formulations and methods of manufacture thereof
EP3568027A4 (en) 2017-01-13 2020-11-11 Aimmune Therapeutics, Inc. WALNUT FLOUR MANUFACTURING PROCESSES AND FORMULATIONS FOR ORAL IMMUNOTHERAPY
JP7498661B2 (ja) 2017-11-02 2024-06-12 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 経口免疫療法の方法

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
CN101883584A (zh) * 2007-12-03 2010-11-10 Dbv技术公司 过敏原脱敏方法
CN101912364A (zh) * 2010-08-09 2010-12-15 刘会梅 银杏内酯b脂质体组合药物
WO2012123759A1 (en) * 2011-03-17 2012-09-20 Cambridge Enterprise Limited Treatment for peanut allergy

Also Published As

Publication number Publication date
AU2016231523A1 (en) 2016-10-06
CN109125283A (zh) 2019-01-04
US9198869B2 (en) 2015-12-01
CN105101994A (zh) 2015-11-25
SI2968529T1 (sl) 2021-03-31
JP6891205B2 (ja) 2021-06-18
JP2019108357A (ja) 2019-07-04
BR112015021756A2 (pt) 2017-07-18
AU2020202685B2 (en) 2022-01-20
EP2968529B1 (en) 2020-08-05
AU2020202685A1 (en) 2020-05-14
AU2022201858B2 (en) 2024-04-04
AU2016231523B2 (en) 2018-05-31
DK2968529T3 (da) 2020-10-12
DK3482771T3 (da) 2023-03-20
EP3482771B1 (en) 2023-01-18
PL2968529T3 (pl) 2021-04-19
JP7454519B2 (ja) 2024-03-22
NO2023027I1 (no) 2023-07-06
BR112015021756A8 (pt) 2019-11-19
US20140271836A1 (en) 2014-09-18
US20200129378A1 (en) 2020-04-30
FI3482771T3 (fi) 2023-04-03
EP3482771A1 (en) 2019-05-15
MX2015010315A (es) 2016-04-13
US10449118B2 (en) 2019-10-22
AU2022201858A1 (en) 2022-04-07
BR112015021756B1 (pt) 2023-01-10
US11141352B2 (en) 2021-10-12
US20160030289A1 (en) 2016-02-04
CA2903229A1 (en) 2014-10-02
AU2014240404B2 (en) 2016-07-21
JP2021073321A (ja) 2021-05-13
JP6752140B2 (ja) 2020-09-09
JP2016512537A (ja) 2016-04-28
FR23C1026I2 (fr) 2024-07-26
ES2826224T3 (es) 2021-05-17
HUE051831T2 (hu) 2021-03-29
HK1217660A1 (zh) 2017-01-20
EP3998080A1 (en) 2022-05-18
WO2014159607A1 (en) 2014-10-02
FR23C1026I1 (fr) 2023-10-06
FIC20230022I1 (fi) 2023-07-04
US20180042816A1 (en) 2018-02-15
PT2968529T (pt) 2020-11-10
EP2968529A1 (en) 2016-01-20
AU2014240404A1 (en) 2015-09-17
NL301236I2 (nl) 2025-07-31
US20230120350A1 (en) 2023-04-20
ES2940686T3 (es) 2023-05-10
EP2968529A4 (en) 2016-10-05
AU2018222980A1 (en) 2018-09-20

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