CN105092865B - Test strips drench sample groove, drench sample system, desiccation analyzer and its drench sample and cleaning method - Google Patents
Test strips drench sample groove, drench sample system, desiccation analyzer and its drench sample and cleaning method Download PDFInfo
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- CN105092865B CN105092865B CN201510438762.4A CN201510438762A CN105092865B CN 105092865 B CN105092865 B CN 105092865B CN 201510438762 A CN201510438762 A CN 201510438762A CN 105092865 B CN105092865 B CN 105092865B
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Abstract
Sample groove is drenched the present invention relates to a kind of test strips, including drenches sample groove body and test paper saddle, drenching sample groove body includes sump pit and the reactive tank with sump pit insertion, and discharge opeing trench bottom is further opened with the conduction hole connected with outside drainage line；Test paper saddle is placed in reactive tank, and has leakage passage between reactive tank, and side of the test paper saddle away from sump pit has inclined spigot surface, will treat that discharging liquid is drained to leakage passage.Above-mentioned test strips drench sample groove, sample flows into leakage passage along spigot surface, sample is set to be flowed along certain path, it ensure that test strips can be fully absorbed, test strips surface will not residual sample, the pollution during subsequent transmission is avoided, and test strips surface will not produce moisture film, so as to improve the accuracy of pattern detection result.A kind of pouring sample system, desiccation analyzer are also provided and its sample and cleaning method is drenched.
Description
Technical field
The present invention relates to medical in-vitro diagnosis equipment technical field, more particularly to a kind of test strips drench sample groove, drench sample system
System, desiccation analyzer and its pouring sample and cleaning method.
Background technology
Urine detection is one of three big conventional projects of modern medicine clinical examination, is played in the diagnosis of disease very heavy
The effect wanted, dry chemical Urine Analyzer be with the matching used clinical urine examination instrumentation of drying chemical reagent paper, utilize reflected light
Electric colorimetric method is measured to the test paper medicine block of dipped urine, is scaled the semi-quantitative results of respective item.
Usually, in clinical trial, test strips are sent to pouring sample groove by connecting gear, and sample is drenched into pouring sample
In groove, then test strips discharge sample after being impregnated with, thus, can avoid drawing because point sample is inaccurate, leak source, point sample are excessive etc.
The error result of the ELISA test strip risen, improves the accuracy of detection to a certain extent.But, it is existing pouring sample groove processing compared with
Complexity, high processing costs, the sample for drenching test paper surface after sample inhales unclean, is easily polluted during subsequent transmission, and
Inhaling sordid sample can cause testing result deviation occur in test paper surface generation moisture film, influence the accuracy of detection.
The content of the invention
Based on this, it is necessary to complicated for existing pouring sample slot structure, high processing costs, test paper surface sample, which is inhaled, not to be done
Only, the problem of easily causing pollution and influence detection accuracy is easier to be inhaled there is provided a kind of sample simple in construction, test paper surface
The test strips walked drench sample groove, drench sample system, desiccation analyzer and its drench sample and cleaning method.
A kind of test strips drench sample groove, including：
Sample groove body is drenched, the pouring sample groove body includes sump pit and the reactive tank with the sump pit insertion, the row
Liquid bath bottom is further opened with the conduction hole connected with outside drainage line；
Test paper saddle, for putting test strips, the test paper saddle is placed in the reactive tank, and with the reactive tank side
There is leakage passage, the one side that the test paper saddle carries the test strips is inclined plane, will treat discharging liquid drainage between wall
To the leakage passage, the leakage passage connects to form a drain path with the sump pit.
Above-mentioned test strips drench sample groove, and sample flows into leakage passage along inclined plane, sample is flowed along certain path, it is ensured that
Test strips can be fully absorbed, test strips surfaces will not residual sample, it is to avoid the pollution during subsequent transmission, and test strips
Surface will not produce moisture film, so as to improve the accuracy of pattern detection result.In addition, the test strips drench sample groove compared to existing
Sample groove is drenched, processing technology is simple, and procedure of processing is few, improves process velocity, and then reduce processing cost.
In a wherein embodiment, the width of the test paper saddle is slightly less than the width of the reactive tank, so that the examination
There is leakage gap between paper saddle and the reaction groove sidewall, and then form the leakage passage.
In a wherein embodiment, what the test paper saddle formed the side wall in the leakage gap is respectively arranged at two ends with first
Butting section, first butting section is resisted against the side wall of the reactive tank, so that the test paper saddle and the reactive tank
The side wall between form the leakage gap.
In a wherein embodiment, the test paper saddle is provided with groove in its length direction, and the groove connects the leakage
Liquid passage.
In a wherein embodiment, the groove is multiple, and laid along the test paper saddle length direction interval.
In a wherein embodiment, the test strips, which drench sample groove, also includes the second butting section, and second butting section is located at
The test paper saddle is towards the side of the side wall of the reactive tank, second butting section one end and the test paper saddle bottom
Facial planes is concordant, and the other end is flushed less than the groove floor or with groove floor；
Wherein, the thickness of second butting section matches with the leakage gap.
In a wherein embodiment, the side edge of the test paper saddle towards the sump pit has some depressions
Portion, some depressed parts are connected with the leakage passage, so as to treat that discharging liquid flows into the sump pit from the leakage passage.
One kind drenches sample system, including above-mentioned test strips drench sample groove and negative pressure unit, and the negative pressure unit includes negative pressure cavity
Body and negative pressure produce component, and the vacuum cavity is connected with the conduction hole by drainage line, also set on the drainage line
There is the control valve for controlling its break-make, the negative pressure, which produces component, includes negative pressure pump and check valve, the negative pressure pump passes through the list
Connected to valve with the vacuum cavity, to provide subnormal ambient for the vacuum cavity.
In a wherein embodiment, the pouring sample system also includes discharging of waste liquid unit, and the discharging of waste liquid unit includes
The waste drains pump connected with the delivery outlet of the vacuum cavity and the waste collecting device connected with the waste drains pump, will be from described
The discharging of waste liquid of the delivery outlet discharge of vacuum cavity is to the waste collecting device.
A kind of desiccation analyzer, including sampling needle, the desiccation analyzer also include above-mentioned pouring sample system, accommodating sample
Test tube, the service sink of accommodating cleaning fluid and the cleaning fluid pipe-line system being connected with the sampling needle by check valve；
The desiccation analyzer also includes driving the test strips to the of the test paper saddle and ELISA test strip unit
One motion, and the sampling needle is controlled along test strips direction level and the second motion moved up and down.
A kind of the pouring sample and cleaning method of desiccation analyzer described above, including step：
1) the first motion is driven above test strips to reactive tank, and test strips is kept horizontality；
2) the second motion is driven above sampling needle to test tube, is quantitatively sucked in test tube after sample, is driven sampling needle extremely
Above test strips；
3) the second motion drives sampling needle to be moved along test strips length direction, while sampling needle will with the speed set
Sample is uniformly discharged in test strips；
4) after test strips fully absorb sample, test strips are placed in test paper saddle by the first motion to be used to carry it
Inclined plane on, and make test strips keep heeling condition；
5) first open check valve and negative pressure pump, are then turned on controlling valve, extract the remaining sample that test strips are drenched in sample groove out, and
Waste drains pump is opened simultaneously, and the waste liquid in vacuum cavity is discharged in waste collecting device；
6) the first motion drives the test strips after absorption sample to ELISA test strip unit to detect；
7) closing control valve, check valve, negative pressure pump and waste drains pump, and control cleaning fluid to flow into reactive tank by sampling needle, clearly
Wash after the scheduled time, open check valve, negative pressure pump, control valve and waste drains pump, take cleaning fluid away and complete the clear of test strips pouring sample groove
Wash.
In a wherein embodiment, the step 3) after also include sampling probe cleaning step, the sampling probe cleaning step
Specifically include following steps：
Second motion drives sampling needle to move in service sink emptying sampling needle and remains sample, and carries out inside and outside sampling needle
The cleaning of wall；
Wherein, the cleaning step and step 4) to step 6) carry out simultaneously, after the completion of cleaning, the second motion drives
Draw above sampling needle to the reactive tank of cleaning fluid and go to step 7).
Brief description of the drawings
Fig. 1 drenches the structural representation of sample groove for the test strips in present pre-ferred embodiments；
Fig. 2 is the structural representation at another visual angle of the test strips pouring sample groove shown in Fig. 1；
Fig. 3 is the sectional view of the test paper pouring sample groove shown in Fig. 1；
Fig. 4 is the partial enlarged drawing at the A for the sectional view that the test paper shown in Fig. 3 drenches sample groove；
Fig. 5 is the structural representation of the test paper saddle shown in Fig. 1；
Fig. 6 is the structural representation at another visual angle of the test paper saddle shown in Fig. 1；
Fig. 7 is that test strips are placed in the cooperation shape that test strips drench sample groove by the first motion in present pre-ferred embodiments
State figure；
Fig. 8 is the structural representation for drenching sample system in present pre-ferred embodiments；
Fig. 9 be present pre-ferred embodiments in desiccation analyzer structural representation.
Embodiment
For the ease of understanding the present invention, the present invention is described more fully below with reference to relevant drawings.In accompanying drawing
Give the preferred embodiment of the present invention.But, the present invention can be realized in many different forms, however it is not limited to herein
Described embodiment.On the contrary, the purpose for providing these embodiments is to make the understanding to the disclosure more saturating
It is thorough comprehensive.
It should be noted that when element is referred to as " being fixed on " another element, it can be directly on another element
Or can also have element placed in the middle.When an element is considered as " connection " another element, it can be directly connected to
To another element or it may be simultaneously present centering elements.Term as used herein " vertical ", " level ", " left side ",
" right side " and similar statement are for illustrative purposes only.
Unless otherwise defined, all of technologies and scientific terms used here by the article is with belonging to technical field of the invention
The implication that technical staff is generally understood that is identical.Term used in the description of the invention herein is intended merely to description tool
The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term as used herein " and/or " include one or more phases
The arbitrary and all combination of the Listed Items of pass.
As shown in Figure 1, Figure 2 and Figure 3, the test strips in present pre-ferred embodiments drench sample groove 10 and include drenching sample groove body 12
And test paper saddle 14.The pouring sample groove body 12 include a sump pit 122 opened up along its length, and with the sump pit 122
The reactive tank 124 of insertion, the bottom of sump pit 122 is further opened with the conduction hole 1222 connected with outside drainage line.The test paper
Saddle 14 is placed in reactive tank 124, and has leakage passage between the side wall of reactive tank 124, and the test paper saddle 14 is for holding
The one side for carrying the test strips is inclined plane 142, will treat that discharging liquid is drained to leakage passage, the leakage passage and sump pit
122 connections form a drain path.
Test strips, which are put, be can be placed in inclined plane 142, during sample is drenched, and test strips are placed in into the top of reactive tank 124 first,
Sampling needle 210 is moved along test strips length direction, uniformly pours sample in test strips, treats that test strips fully absorb sample
Afterwards, test strips are placed in inclined plane 142, treat that discharging liquid enters sump pit 122 by inclined plane 142 and discharged.Due to test paper
Saddle 14 has leakage passage with the side wall of reactive tank 124, and it has inclined plane 142, and sample flows into leakage along inclined plane 142 and led to
Road, thus, making sample be flowed along certain path, it is ensured that test strips can be fully absorbed, test strips surface will not residual sample,
The pollution during subsequent transmission is avoided, and test strips surface will not produce moisture film, so as to improve pattern detection result
Accuracy.In addition, the test strips drench sample groove 10 compared to existing pouring sample groove, processing technology is simple, and procedure of processing is few, improves and adds
Work speed, and then reduce processing cost.
Specifically, in the present embodiment, as shown in Figures 1 and 3, the pouring sample groove body 12 is in rectangular-shape, using turnning and milling work
Skill or wire cutting technology open up sump pit 122 and the reactive tank 124 with the insertion of sump pit 122, the discharge opeing along its length
The width of groove 122 is less than the width of the reactive tank 124, so that the supporting surface 1242a and supporting surface 1242b at two intervals are formed,
Finally conduction hole 1222 is opened up in the bottom of sump pit 122, then connected by drainage line 40 with the vacuum cavity 22 being separately provided.
Test paper saddle 14 is also in rectangular-shape, its matching size with reactive tank 124, and is placed in supporting surface 1242a and supporting surface
On 1242b, the height of test paper saddle 14 matches with the depth of reactive tank 124, to avoid sample or cleaning fluid from overflowing.Need explanation
, test paper saddle 14 refers to the matching size of reactive tank 124, coordinates between test paper saddle 14 and reactive tank 124 for gap, can
The basic fixed position test paper saddle 14, in the case where applying a certain size default external force, can take test paper saddle 14 from reactive tank 124
Go out；The height of test paper saddle 14 is matched with the depth of reactive tank 124 to be referred to, the height of test paper saddle 14 is substantially with drenching sample groove body
12 top is concordant, that is to say, that in the present embodiment, the notch side at the higher edge in the position of inclined plane 142 and reactive tank 124
Edge is concordant.
It is appreciated that in the present embodiment, by setting the width of sump pit 122 to be less than the width of reactive tank 124 to be formed
Two supporting surface 1242a and supporting surface 1242b, so that test paper saddle 14 is placed in reactive tank 124.In some other embodiment
In, other modes can also be taken, are not limited thereto, for example, support is set in sump pit 122, to support test paper saddle
14。
Also referring to Fig. 4, in the present embodiment, the width of the test paper saddle 14 is slightly less than the width of reactive tank 124, so that
Make that there is leakage gap 16 between test paper saddle 14 and the side wall of reactive tank 124, and then form foregoing leakage passage.Such as Fig. 3 institutes
Show, in the present embodiment, the side wall of the test paper saddle 14 is resisted against the side wall 126a of reactive tank 124, and test paper saddle 14 is relative
Opposite side wall two ends form the first butting section (figure is not marked) respectively, and first butting section is resisted against the side wall 126b of reactive tank 124,
So that the part between the butting section of test paper saddle 14 first and formation leakage gap 16 between the side wall 126b of reactive tank.It is preferred that
Ground, first butting section can be against bar or abutment face, specific in embodiment as shown in Figures 5 and 6, the test paper saddle 14
Orientating reaction groove sidewall 126b side have a low degree 144 and positioned at the two ends of low degree 144 high plane 146 (against
Face), the high plane 146 is resisted against the side wall 126b of the reactive tank 124, so that by the basic fixed position of test paper saddle 14 in the reactive tank
In 124, the leakage gap 16 is formed between the low degree 144 and the side wall 126b, sample and cleaning fluid can be along inclined planes
142 flow to the leakage gap 16, so as to flow into sump pit 122.
It is appreciated that the form of leakage passage can be other forms, in the present embodiment, the leakage passage is test paper saddle 14
The leakage gap 16 formed between reaction groove sidewall 126b, in some other embodiment, the leakage passage can also be to incline
The relatively low edge in inclined-plane 142 vertically opens up liquid-leaking nozzle, or sets multiple support columns on the side wall of test paper saddle, makes the row for the treatment of
Liquid is from leaking into sump pit 122 between multiple support columns.
Please continue to refer to Fig. 6, in the present embodiment, the test paper saddle 14 has towards the side edge of the sump pit 122
There are some depressed parts 148, the depressed part 148 is connected with leakage gap 16, arranged so as to treat that discharging liquid is flowed into from the leakage gap 16
Liquid bath 122.Specifically, the depressed part 148 is moved towards another lateral edges for edge of the milling cutter along the base plane of test paper saddle 14 and added
Some grooves of work formation, the total length of some depressed parts 148 is less than the total length of test paper saddle 14, the depressed part 148
Width is more than the width that test paper saddle 14 is placed in the supporting surface 1242b of reactive tank 124.More clearly say, some depressed parts
148 total length is less than the length of test paper saddle 14, the base plane of test paper saddle 14 is stably supported at its both ends and puts
In two supporting surface 1242a, 1242b, make test paper saddle 14 can level be placed in reactive tank 124, the width of the depressed part 148 is big
In supporting surface 1242b width, leakage gap 16 is set to be connected with sump pit 122, can be by so that in the presence of inclined plane 142
Sample or cleaning fluid pass through in the quick drainage of leakage gap 16 to sump pit 122.
It should be appreciated that in the present embodiment, to improve the stability that test paper saddle 14 is put, the depressed part 148 is spaced
Set, multiple abutted so that the base plane of test paper saddle 14 has close to the edge in leakage gap 16 with supporting surface 1242b
Contact surface, and then improve the stability of the storing of test paper saddle 14.Certainly, in other embodiments, the depressed part 148 may not be used yet
Interval setting, is not limited thereto.
It is appreciated that in the present embodiment, sump pit 122 and leakage gap 16 are connected by setting depressed part 148, at other
In some embodiments, other modes can be also used, are not limited thereto.For example, making two supporting surface 1242a, 1242b height phase
Different, the supporting surface 1242b close to leakage gap 16 is relatively low supporting surface, sets multiple intervals to set on supporting surface 1242b
The support column put, the height of the support column is equal with two supporting surface 1242a, 1242b difference in height, so that sample or cleaning fluid
Can between multiple support columns enter sump pit 122.
Referring to Fig. 5, the test paper saddle 14 is also spaced laying fluted 149 in its length direction, and the groove 149 connects
Lead to the leakage gap 16.Specifically, the test paper saddle 14 has inclined plane 142, and the groove 149 is opened in the inclined plane 142, excellent
Selection of land, the width of the groove 149 along test paper saddle 14 is opened up.Thus, being easy to quickly empty cleaning fluid, make to be rapidly completed
Matting, improves operating efficiency, in addition, the holding part 252 for being also convenient for the first motion 250 stretches into the groove 149, from
And drive test strips to move.As shown in fig. 7, in the present embodiment, two holding parts 252 are two grabs, groove 149, which is played, keeps away position work
With in operation, the clamping hook arm of two holding parts 252 is placed in groove 149, and test strips are placed in the inclination of test paper saddle 14
As the same on face 142, when needing test strips removing reactive tank 124, two holding parts 252 depart from groove, and support test strips to incite somebody to action
Test strips are removed.Preferably, as shown in figure 3, the side wall 126b of reactive tank 124 is additionally provided with bit-avoiding slot 128, to be further easy to card
The clamping hook arm of gripping member 252 is stretched into and removed from groove 149.
It is appreciated that the quantity of the groove 149 and opening up position and can set as the case may be, it is not limited thereto.Example
Such as, the groove 149 can be realized and be easy to the first motion depending on the specific setting according to the holding part 252 of the first motion
Test strips are placed in the inclined plane 142 of test paper saddle 14, and the purpose removed by mechanism.
Referring to Fig. 5 and Fig. 6, the side wall of test paper saddle 14 has a low degree 144 and positioned at 144 liang of the low degree
The high plane 146 at end, the high plane 146 is resisted against the side wall 126b of the reactive tank 124, so that by the basic fixed position of test paper saddle 14
In in the reactive tank 124.Really, by the basic fixed position of test paper saddle 14 in the reactive tank 124, the low degree 144 and the side
The leakage gap 16 is formed between wall 126b, is the stabilization positioned between further increase test paper saddle 14 and reactive tank 124
Property, it is to avoid foregoing first butting section (high plane 146) is worn and torn with the side wall of test paper saddle 14 during assembling or use, leads
Cause leakage gap 16 to reduce and influence leakage effect, the test strips, which drench sample groove 10, also includes the second butting section 147, this second against
Portion 147 is fixed in test paper saddle 14 towards the side of the side wall 126b, wherein, the thickness of second butting section 147 and leakage
Gap 16 matches.More precisely, the thickness of second butting section 147 is substantially equal sized with leakage gap 16, makes second
Butting section 147 can be resisted against the side wall of the reactive tank 124, so as to avoid test paper saddle 14 from occurring in the width of reactive tank 124
It is mobile, and then ensure the stability of the size of leakage gap 16.
In the present embodiment, second butting section 147 is integrally formed with test paper saddle 14, i.e., pass through machinery by one block of material all in one piece
Processing is formed, and it is located at groove 149, thus, second butting section 147, which can also strengthen test paper saddle 14, opens up fluted
Intensity at 149, improves the reliability of test paper saddle 14, extends service life.It may be noted that second butting section 147
One end is concordant with the base plane of test paper saddle 14, so that test paper saddle 14, which can be stablized, be placed in supporting surface 1242a, 1242b, this
The other end of two butting section 147 is concordant with the bottom surface of groove 149 or bottom surface less than groove 149, so as to ensure sample or cleaning fluid
Leakage gap 16 can be flowed to from the groove 149.
It should be appreciated that when the bottom surface of the groove 149 is parallel with the base plane of test paper saddle 14, then second butting section
147 ends being open close to reactive tank 124 are concordant with the bottom surface of the groove 149 or less than the bottom surface of groove 149, when the groove 149
When bottom surface is an inclined plane, such as when parallel with inclined plane 142, then second butting section 147 should be with the bottom surface of groove 149
A relatively low end margin is concordant or less than it, so as to ensure that sample or cleaning fluid can flow out from the groove 149.
Sample groove 10 is drenched based on the test strips provided in above-described embodiment, as shown in figure 8, the present invention also provides a kind of pouring sample system
System 100, it includes above-mentioned test strips and drenches sample groove 10, negative pressure unit 20 and discharging of waste liquid unit 30, and the negative pressure unit 20 includes negative
Pressure cavity 22 and the negative pressure connected with the vacuum cavity 22 produce component 24.
Specifically, the vacuum cavity 22 includes two input ports, wherein an input port passes through drainage line 40 and conduction hole
1222 connections, the drainage line 40 is provided with the control valve 50 for controlling its break-make, it is preferable that the control valve 50 is magnetic valve, can
Opened in the sample and/or cleaning fluid in needing emptying sump pit 122.Wherein another input port of the vacuum cavity 22 is with bearing
Pressure produces component 24 and connected, and to provide subnormal ambient for the vacuum cavity 22, the discharging of waste liquid unit 30 includes and vacuum cavity
The waste drains pump 32 of 22 delivery outlet connection and the waste collecting device 34 connected with the waste drains pump 32, will be from the vacuum cavity 22
Delivery outlet discharge discharging of waste liquid to the waste collecting device 34.
When needing the sample in sump pit 122 and/or cleaning fluid discharge, open negative pressure and produce component 24, make negative pressure
Cavity 22 is in subnormal ambient, at the same time, opens control valve 50, the sample and/or cleaning fluid of sump pit 122 are by outside gas
Pressure is acted on, and is flowed into from conduction hole 1222 by controlling valve 50 in vacuum cavity 22.The delivery outlet and waste drains pump of vacuum cavity 22
32 connections, waste drains pump 32 provides the discharge opeing power of discharge sample and/or cleaning fluid, then delivery outlet stream of the waste liquid from vacuum cavity 22
To waste drains pump 32, and waste collecting device 34 is finally flowed into, specific in the present embodiment, the waste collecting device 34 is waste liquid
Bottle.Thus, individually setting up vacuum cavity 22, larger vacuum can be formed in moment, test strips are after sample is drenched, the sample on its surface
Easily saddle being tilted along test paper and flowing into sump pit 122, and siphoned away by moment, further ensuring test strips surface will not remain
Sample, it is to avoid the pollution during subsequent transmission, and test strips surface will not produce moisture film, so as to improve pattern detection knot
The accuracy of fruit.
Preferably, as shown in figure 8, the negative pressure, which produces component 24, includes negative pressure pump 242 and check valve 244, the negative pressure pump 242
Connected by the check valve 244 with another input port of the vacuum cavity 22.The setting of check valve 244 makes to protect in vacuum cavity 22
Hold certain negative pressure, it is ensured that sample and/or cleaning fluid in sump pit 122 have enough drainage power to be discharged from sump pit 122,
And then make test strips surface will not residual sample, sample and/or cleaning fluid can be drenched in sample groove 10 from test strips to be extracted out, it is to avoid influence
The accuracy of testing result.
It should be noted that check valve 244 is the mature technology of mechanical field, therefore its concrete structure and original are not repeated herein
Reason.
As shown in Figure 8 and Figure 9, the present invention also provides a kind of desiccation analyzer 200, and the desiccation analyzer 200 includes sampling
Pin 210, above-mentioned pouring sample system 100, the test tube 220 of accommodating sample, the service sink 230 of accommodating cleaning fluid and with the sampling needle 210
The cleaning fluid pipe-line system (not shown) connected by check valve.
Sample is housed in test tube 220, the sample in test tube 220 sampled by sampling needle 210, and be added to test strips
Drench in sample groove 10, after the completion of sample-adding, sampling needle 210, which is put into service sink 230, completes outer wall washing work.Test strips drench sample groove 10
Need to carry out cleaning fluid cleaning after the completion of experiment, the pollution for preventing the sample of residual from detecting subsequent samples, sampling needle
The top that test strips drench sample groove 10 is moved to after 210 absorption cleaning fluids, by opening cleaning fluid pipe-line system, check valve is opened,
Cleaning fluid spits into test strips by sampling needle 210 and drenched in sample groove 10, after immersion a period of time, opens negative pressure pump 242, check valve
244th, valve 50 is controlled, and opens waste drains pump 32 simultaneously, so that waste liquid is discharged into waste collecting device 34, cleaning test strips is completed and drenches
The work of sample groove 10.
Specifically, as shown in fig. 7, the desiccation analyzer 200 also includes driving the test strips to the test paper saddle 14 and examination
First motion 250 of paper slip detection unit (not shown), and control sampling needle is along test strips direction level and moves up and down
The second motion (not shown).Test strips are moved to the reactive tank that test strips drench sample groove 10 by first motion 250
124 tops, drench after the completion of sample, test strips are placed in the inclined plane of test paper saddle 14 by the first motion 250, then, waste liquid
Discharged by sump pit 122, the first motion 250 drives test strips to ELISA test strip unit to detect, is finally moved to give up
In carton.Second motion can drive sampling needle 210 to be moved horizontally between test tube 220 and test strips drench sample groove 10, and
Sample sampling can be completed by moving up and down, or complete pouring sample work close to test strips.
It should be noted that the emphasis of the present invention does not lie in the specific knot of the first motion 250 and the second motion
Structure, therefore, will not be repeated here its specific structure and principle, can realize foregoing function, the first motion shown in Fig. 7
Mechanism 250 is the first motion 250 shown in present pre-ferred embodiments, but therefore can not be interpreted as to invention
The limitation of the scope of the claims.
The present invention also provides a kind of desiccation analyzer 200 and drenches sample and cleaning method, comprises the following steps：
1) the first motion 250 drives test strips to the top of reactive tank 124, and test strips is kept horizontality；
Specifically, two holding parts 252 of the first motion 250 drive test strips to the top of reactive tank 124, test strips
On the clamping hook arm for being placed in the level of holding part 252, so as to keep horizontality.
2) the second motion drives sampling needle 210 to the top of test tube 220, quantitatively sucks in test tube 220 after sample, drives
Above sampling needle 210 to test strips.
Specifically, the second motion drives sampling needle 210 to move horizontally, and is moved to the position of test tube 220, quantitative suction examination
Sample in pipe 220, then drives sampling needle 210 to move back to above test strips, test strips are placed in the grab of the level of holding part 252
On arm.
3) the second motion drives sampling needle 210 to be moved along test strips length direction, while sampling needle 210 is with setting
Sample is uniformly discharged in test strips by speed；
Specifically, second motion drives length direction of the sampling needle 210 along test strips at the uniform velocity to move, and samples simultaneously
Sample is uniformly discharged in test strips by pin 210 with the frequency of setting.
4) after test strips fully absorb sample, test strips are placed in test paper saddle 14 by the first motion 250 to be used for
Carry in its inclined plane 142, and test strips is kept heeling condition；
Specifically, two holding parts 252 of the first motion 250 are stretched into groove 149, and test strips are then attached at test paper support
In the inclined plane 142 of platform 14, so as to keep heeling condition, make to treat that discharging liquid is flowed into sump pit 122 from leakage gap 16.
5) first open check valve 244 and negative pressure pump 242, are then turned on controlling valve 50, extract test strips out and drench in sample groove 10
Remaining sample, and waste drains pump 32 is opened simultaneously, the waste liquid in vacuum cavity 22 is discharged in waste collecting device 34.
Specifically, the sample unnecessary etc. test strips is drained to after sump pit 122, first open check valve 244 and negative pressure pump
242, larger vacuum is produced in vacuum cavity 22, is then turned on controlling valve 50, then the sample in sump pit 122 and reactive tank 124
This is by the negative suction cavity 22 of conduction hole 1222.Waste drains pump 32 is opened simultaneously there is provided discharge opeing power, by vacuum cavity 22
Waste liquid be drawn in waste collecting device 34.
6) the first motion 250 drives the test strips after absorption sample to ELISA test strip unit to detect；
Specifically, after sample is racked up, the first motion retains test strips by its holding part 252, and drives examination
Paper slip is moved to the detection of ELISA test strip unit, and obtains the testing result of sample.
7) closing control valve 50, check valve 244, negative pressure pump 242 and waste drains pump 32, and cleaning fluid is controlled by sampling needle 210
Reactive tank 124 is flowed into, after the cleaning scheduled time, open check valve 244, negative pressure pump 242, control valve 50 and waste drains pump 32 are taken away
Cleaning fluid completes the cleaning that test strips drench sample groove 10.
Specifically, after sample raffinate is completely exhausted out, closing control valve 50, check valve 244, negative pressure pump 242 and waste drains pump 32,
The detergent line that sampling needle 210 is connected is opened, cleaning fluid was delivered to after reactive tank 124, the scheduled time by sampling needle 210,
Cleaning fluid is fully cleaned to test paper saddle 14, reactive tank 124 and sump pit 122, is then turned on check valve 244, negative pressure pump
242nd, control valve 50 and waste drains pump 32, so that cleaning fluid is pumped to waste collecting device 34 by conduction hole 1222, complete examination
Paper slip drenches the cleaning of sample groove 10, it is to avoid test strips drench residual sample in sample groove 10 and cause the cross pollution between sample, influence
Follow-up detection, so as to improve the accuracy and reliability of detection.It should be noted that cleaning fluid is first flowed by sampling needle 210
Enter reactive tank 124, to being cleaned successively to test paper saddle 14, reactive tank 124, sump pit 122 and conduction hole 1222 etc., so that
Complete the cleaning that test strips drench sample groove 10.
In a wherein embodiment, the step 3) after also include the cleaning step of sampling probe, it specifically includes following steps：
Second motion drives sampling needle 210 to move in the emptying sampling needle 210 of service sink 230 and remains sample, and carries out
The cleaning of sampling needle inside and outside wall；
Specifically, the second motion drives sampling needle 210 to move to the sample remained in the top of service sink 230 emptying sampling needle
This, then drives sampling needle 210 to be moved in service sink 230, completes the cleaning of the inside and outside wall of sampling needle by the second motion.
Thus, passing through comprehensive cleaning to sampling needle 210, it is to avoid in different sampling processes, cross pollution is caused to sample.
Wherein, the cleaning step and step 4) to step 6) carry out simultaneously, after the completion of cleaning, the second motion, which drives, to be inhaled
The sampling needle 210 of cleaning fluid is taken to the top of reactive tank 124 and enters step 7) so that each working portion recovers to predetermined
Position, is easy to being normally carried out for follow-up test.
Each technical characteristic of embodiment described above can be combined arbitrarily, to make description succinct, not to above-mentioned reality
Apply all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, the scope of this specification record is all considered to be.
Embodiment described above only expresses the several embodiments of the present invention, and it describes more specific and detailed, but simultaneously
Can not therefore it be construed as limiting the scope of the patent.It should be pointed out that coming for one of ordinary skill in the art
Say, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention
Scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (11)
1. a kind of test strips drench sample groove, it is characterised in that including：
Sample groove body is drenched, the pouring sample groove body includes sump pit and the reactive tank with the sump pit insertion, the sump pit
Bottom is further opened with the conduction hole connected with outside drainage line；
Test paper saddle, for putting test strips, the width of the sump pit is less than the width of the reactive tank, so as to be formed between two
Every the supporting surface of setting, the test paper saddle is placed on two supporting surface in the reactive tank, and with the reactive tank side
There is leakage passage, the one side that the test paper saddle carries the test strips is inclined plane, will treat discharging liquid drainage between wall
To the leakage passage, the leakage passage connects to form a drain path with the sump pit；The test paper saddle is towards institute
Stating the side edge of sump pit has some depressed parts, and some depressed parts are connected with the leakage passage, so that the row for the treatment of
Liquid flows into the sump pit from the leakage passage.
2. test strips according to claim 1 drench sample groove, it is characterised in that the width of the test paper saddle is slightly less than described
The width of reactive tank, so as to have leakage gap between the test paper saddle and the reaction groove sidewall, and then forms the leakage
Liquid passage.
3. test strips according to claim 2 drench sample groove, it is characterised in that the test paper saddle forms the leakage gap
Side wall be respectively arranged at two ends with the first butting section, first butting section is resisted against the side wall of the reactive tank so that
The leakage gap is formed between the side wall of the test paper saddle and the reactive tank.
4. test strips according to claim 3 drench sample groove, it is characterised in that the test paper saddle is provided with its length direction
Groove, the groove connects the leakage passage.
5. test strips according to claim 4 drench sample groove, it is characterised in that the groove is multiple, and along the test paper
Lay at saddle length direction interval.
6. test strips according to claim 5 drench sample groove, it is characterised in that the test strips are drenched sample groove and also supported including second
Relying part, second butting section is supported located at the test paper saddle towards the side of the side wall of the reactive tank, described second
Relying part one end is concordant with the test paper saddle base plane, and the other end is flushed less than the groove floor or with groove floor；
Wherein, the thickness of second butting section matches with the leakage gap.
7. one kind drench sample system, it is characterised in that including as described in claim 1~6 any one test strips pouring sample groove and
Negative pressure unit, the negative pressure unit includes vacuum cavity and negative pressure produces component, and the vacuum cavity passes through drainage line and institute
State and the control valve for controlling its break-make is additionally provided with conduction hole connection, the drainage line, the negative pressure, which produces component, includes negative pressure
Pump and check valve, the negative pressure pump are connected by the check valve with the vacuum cavity, to provide negative for the vacuum cavity
Pressure ring border.
8. pouring sample system according to claim 7, it is characterised in that the pouring sample system also includes discharging of waste liquid unit,
The discharging of waste liquid unit include waste drains pump connect with the delivery outlet of the vacuum cavity and connected with the waste drains pump give up
Liquor collecting device, by the discharging of waste liquid of the delivery outlet discharge from the vacuum cavity to the waste collecting device.
9. a kind of desiccation analyzer, including sampling needle, it is characterised in that the desiccation analyzer also includes such as claim 7~8
Pouring sample system described in any one, the test tube of accommodating sample, the service sink of accommodating cleaning fluid and pass through list with the sampling needle
The cleaning fluid pipe-line system connected to valve；
The desiccation analyzer also includes driving the test strips to the first fortune of the test paper saddle and ELISA test strip unit
Motivation structure, and the sampling needle is controlled along test strips direction level and the second motion moved up and down.
10. a kind of the pouring sample and cleaning method of desiccation analyzer as claimed in claim 9, it is characterised in that including step：
1) the first motion is driven above test strips to reactive tank, and test strips is kept horizontality；
2) the second motion is driven above sampling needle to test tube, is quantitatively sucked in test tube after sample, drives sampling needle to test paper
Above bar；
3) the second motion drives sampling needle to be moved along test strips length direction, at the same sampling needle with the speed that sets by sample
Uniformly it is discharged in test strips；
4) after test strips fully absorb sample, test strips are placed in test paper saddle by the first motion to be used to carry inclining for its
On inclined-plane, and test strips are made to keep heeling condition；
5) first open check valve and negative pressure pump, are then turned on controlling valve, extract the remaining sample that test strips are drenched in sample groove out, and simultaneously
Waste drains pump is opened, the waste liquid in vacuum cavity is discharged in waste collecting device；
6) the first motion drives the test strips after absorption sample to ELISA test strip unit to detect；
7) closing control valve, check valve, negative pressure pump and waste drains pump, and control cleaning fluid to flow into reactive tank by sampling needle, cleaning is pre-
After fixing time, open check valve, negative pressure pump, control valve and waste drains pump take cleaning fluid away and complete the cleaning that test strips drench sample groove.
11. desiccation analyzer according to claim 10 drenches sample and cleaning method, it is characterised in that the step 3) go back afterwards
Including sampling probe cleaning step, the sampling probe cleaning step specifically includes following steps：
Second motion drives sampling needle to move in service sink emptying sampling needle and remains sample, and carries out sampling needle inside and outside wall
Cleaning；
Wherein, the cleaning step and step 4) to step 6) carry out simultaneously, after the completion of cleaning, the second motion, which drives, to be drawn
The sampling needle of cleaning fluid is to reactive tank top and goes to step 7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510438762.4A CN105092865B (en) | 2015-07-23 | 2015-07-23 | Test strips drench sample groove, drench sample system, desiccation analyzer and its drench sample and cleaning method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510438762.4A CN105092865B (en) | 2015-07-23 | 2015-07-23 | Test strips drench sample groove, drench sample system, desiccation analyzer and its drench sample and cleaning method |
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| Publication Number | Publication Date |
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| CN105092865A CN105092865A (en) | 2015-11-25 |
| CN105092865B true CN105092865B (en) | 2017-07-18 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110389057A (en) * | 2018-04-23 | 2019-10-29 | 上海伯顿医疗设备有限公司 | Integrated multi-functional biological sample processor |
| CN109541250A (en) * | 2018-12-18 | 2019-03-29 | 新绎健康科技有限公司 | A kind of drainage structure |
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| WO2011060387A1 (en) * | 2009-11-13 | 2011-05-19 | Ventana Medical Systems, Inc. | Thin film processing apparatuses for adjustable volume accommodation |
| WO2013123661A1 (en) * | 2012-02-23 | 2013-08-29 | 爱威科技股份有限公司 | Test strip dispensing device for fully-automatic dry chemical analyzer |
| CN103808947B (en) * | 2014-03-11 | 2014-12-03 | 爱威科技股份有限公司 | Test strip sample pouring groove, drying analyzer and sampling pouring and cleaning method of drying analyzer |
| CN104007270B (en) * | 2014-03-20 | 2016-08-17 | 欧蒙医学诊断（中国）有限公司 | A kind of analytical equipment of biological detection |
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