CN105077249A - Conjugated linoleic acids capsule and preparation method thereof - Google Patents
Conjugated linoleic acids capsule and preparation method thereof Download PDFInfo
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- CN105077249A CN105077249A CN201510560683.0A CN201510560683A CN105077249A CN 105077249 A CN105077249 A CN 105077249A CN 201510560683 A CN201510560683 A CN 201510560683A CN 105077249 A CN105077249 A CN 105077249A
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
The invention belongs to the technical field of oil production, and particularly relates to a conjugated linoleic acids capsule and a preparation method thereof. The conjugated linoleic acids capsule is prepared from the following raw materials: conjugated linoleic acids, modified edible starch and water, wherein the weight ratio of conjugated linoleic acids to modified edible starch to water is 1: 1: 3. The conjugated linoleic acids capsule is uniform in particle size, loose and good in fluidity.
Description
Technical field
The invention belongs to the technical field that grease class is produced, be specifically related to a kind of CLA microcapsules and preparation method thereof.
Background technology
CLA (Conjugatedlinoleicacids, CLA) is a series of general names with the isomers of position and stereomeric octadecadienoic acid, is be prevalent in the nutriment in humans and animals body.A large amount of scientific researches proves, CLA, conjugated linoleic acid ethyl ester, conjugated linoleic acid triglyceride have antitumor, anti-oxidant, reduce animal and human's body cholesterol and triglycerides and LDL-C, antiatherosclerosis, raising immunity, improve skeleton density, prevent and treat the multiple important physiological function such as diabetes, animal and human's body fat can also be reduced, increase muscle.
CLA is a kind of novel nourishing additive, a large amount of for agricultural and food industry.CLA can participate in decomposition and the metabolism of fat, and entice energy utilizes and realizes the decline of body weight, and not depot fat, can relax immunoreactive side effect, CLA also can improve some physiological status of the mankind.Research shows, CLA take part in intracellular chemical process, and concrete effect is as follows:
(1) antitumaous effect: the white mouse participating in experiment is studied, discovery CLA can reduce cutaneum carcinoma, cancer of the stomach, breast cancer, colon cancer and the thymic carcinoma that carcinogenic substance causes; The CLA of physiological concentration can kill or suppress human malignant melanoma, colorectal cancer and chest cancer cultureed cells.In addition, CLA can also regulate the activity of Cytochrome P450, the activity of the enzyme such as ornithine deshydroxy enzyme, protein kinase C suppressing the process of cancer to relate to.CLA also can the synthesis of protein and nucleic acid in inhibition cancer cell.Linoleic acid improves cancer level sometimes in zoopery, and CLA watches for animals from the infringement of cancer, is unique a kind of carcinogenesis food be associated with animal foodstuff.In General Requirements food, the content of CLA is between 0.15%-1%, and in the food of normal person, its quantity is enough to prevent cancer and play other physiologically active.
(2) artery sclerosis is prevented: CLA has useful effect to atherosclerotic.Within 1994, Lee with the addition of CLA in daily ration, reduce the concentration of T-CHOL and low-density lipoprotein (LDL)-cholesterol in rabbit blood plasma, change the ratio of high and low density lipoprotein-cholesterol, suppress atherosclerotic generation, and cause established arteriosclerotic partial disappearance.The research of Stang in 2000 etc. also has similar report.Separately have report, CLA can stop fat and blood platelet to precipitate on the arterial wall of atherosclerotic pathology, and this may be that CLA resists atherosis major reason, and its effect is linoleic 5 times.
(3) improve body's immunity and improve metabolism of bone tissue: Watkins research confirms that CLA can promote cell division, organizes muscle deterioration, delays the decline of body immunity.CLA can also promote classification and the regeneration of bone tissue, promotes the synthesis as soft tissue cells and the precipitation of mineral matter in bone tissue, has positive effect to the health of sclerotin.This may be the result of PGE2 concentration adjustment, and PGE2 excessive concentration can suppress the synthesis of sclerotin, and CLA effectively can reduce the concentration of CLA, thus can promote the formation of sclerotin.
(4) antiobesity action: now existing many patents about " CLA reduces body fat in animal body " and bibliographical information, wherein t10, c12-CLA are the major bioactive form suppressing fat deposition.The antiobesity action of CLA may have following mechanism: (a) accumulation by regulating lipid metabolism and energetic supersession to reduce fat; B () CLA realizes its antiobesity action by the apoptosis of Inhibit proliferaton and inducing adipocyte; C () Leptin may mediate the effect that CLA reduces body fat.In people and mouse, all observe the level that CLA can reduce rapidly the CLA in blood, may be one of anti-mechanism of obesity of CLA.
(5) other effects: conjugated linoleic acid CLA has non-oxidizability, and its conjugated double bond is more oxidizable.CLA also have improve feed tire, anti-mildew effect, its sodium salt can mould fungus inhibition growth, have no side effect, character is relatively stable.
CLA and derivative thereof are applied in cosmetics and external preparation for skin medicine product as main active in recent years, have obvious anti-cutaneum carcinoma, nourishing and moisturizing, crease-resistant, the effect such as antiallergy, increase skin elasticity and whitening.
CLA is as the newfound nutrient of one, no matter be as medicine, health food, functional food, food preservative, or in meat industry, feed industry, its further research is significant, in cosmetics, food, feed addictive, have fabulous application prospect.
CLA, conjugated linoleic acid ethyl ester, conjugated linoleic acid triglyceride all belong to grease series products, but by itself characteristic, grease series products determines that its non-oxidizability and packaging and transport all can be subject to certain restrictions, liquid fat series products not easily processes storage.
Summary of the invention
The object of the invention is to the defect for above-mentioned existence and a kind of CLA microcapsules and preparation method thereof are provided, the epigranular of these CLA microcapsules, loose, good fluidity.
Technical scheme of the present invention is: a kind of CLA microcapsules, is made up of following raw material: CLA, sex change food starch and water; Wherein CLA by weight: sex change food starch: water is 1:1:3.
Described CLA microcapsules, are made up of the raw material of following weight portion: CLA 23 ~ 26 parts; Sex change food starch 23 ~ 26 parts; 69 ~ 78 parts, water.
Described CLA microcapsules, are made up of the raw material of following weight portion: CLA 25 parts; Sex change food starch 25 parts; 75 parts, water.
The preparation method of described CLA microcapsules, comprises the following steps:
(1) raw material preparation: take CLA, sex change food starch and water respectively; Wherein CLA by weight: sex change food starch: water is 1:1:3;
(2) mixing and emulsifying: above-mentioned raw materials is added in emulsifying kettle and carries out fully emulsifiedly obtaining emulsion, wherein emulsification 30 minutes;
(3) homogeneous: the emulsion of step (2) gained is added to high-shear homogenizer and carries out shear and homogenize; Adjustment homogenizer feed pressure is no more than 10MPa, ensures that pressure carries out homogeneous continuously; Reaching 8 ~ 10MPa timing at pressure to be switched in spraying metering kettle by material, the material before pressure does not reach at emulsifying kettle Inner eycle, until by whole for material homogeneous to spraying in still;
(4) spraying dry: start after homogeneous to spray, open spraying air-introduced machine, open steam, electrical heating, open spraying nozzle motor, vibrator, spraying starts water inlet spray, when temperature reaches 250 DEG C, start charging, control outlet temperature at 90 DEG C ~ 120 DEG C, ensure temperature continuous feed; Control the charging rate of screw pump, wherein controlling screw pump voltage is 15V ~ 25V; Control water content≤10%, sampling detects;
(5) pack, put storage in storage.
In described step (1), sex change food starch is denaturation cornstarch.
The specifications and models of described denaturation cornstarch are CO-01.
Beneficial effect of the present invention is: the preparation method of CLA microcapsules of the present invention adopts sex change food starch to be capsule material, through high-pressure homogeneous, spraying dry, CLA is embedded in capsule material, make powder, the liquid charging stock solidification of not easily processing storage is formed microcapsules.In the process of microencapsulation, heating temperature is low, the time is short; Composition is not impaired, be not oxidized; And the epigranular of gained CLA microcapsules, loose, good fluidity; Product embedding rate more than 99%, not broken, shelf-life stablizes.
The quality index of CLA microcapsules of the present invention is as follows:
Detailed description of the invention
Below by embodiment, the present invention will be described in detail.
Embodiment 1
Described CLA microcapsules, are made up of the raw material of following weight portion: CLA 23kg; Sex change food starch 23kg; Water 69kg.
The preparation method of described CLA microcapsules, comprises the following steps:
(1) raw material preparation: take 23kg CLA respectively, denaturation cornstarch that 23kg specifications and models are CO-01 and 69kg water;
(2) mixing and emulsifying: be added to by above-mentioned raw materials in emulsifying kettle, opens the mulser on emulsifying kettle, carries out emulsification 30 minutes; Observe emulsification situation, it is floating without oily that material reaches surface, is considered as emulsification complete;
(3) homogeneous: the emulsion of step (2) gained is added to high-shear homogenizer and carries out shear and homogenize; Start homogenizer, adjustment homogenizer feed pressure is no more than 10MPa, and observe adjustment pressure, pressure carries out homogeneous continuously to make it ensure; Reaching 8 ~ 10MPa timing at pressure to be switched in spraying metering kettle by material, the material before pressure does not reach at emulsifying kettle Inner eycle, until by whole for material homogeneous to spraying in still;
(4) spraying dry: spray after homogeneous, spraying starts water inlet spray, when temperature reaches 250 DEG C, start charging, controls outlet temperature at 90 DEG C ~ 120 DEG C, ensures temperature continuous feed; Control the charging rate of screw pump, wherein controlling screw pump voltage is 15V ~ 25V; Control water content≤10%, sampling detects;
(5) pack, put storage in storage.
Embodiment 2
Described CLA microcapsules, are made up of the raw material of following weight portion: CLA 26kg; Sex change food starch 26kg; Water 78kg.
The preparation method of described CLA microcapsules, comprises the following steps:
(1) raw material preparation: take 26kg CLA respectively, denaturation cornstarch that 26kg specifications and models are CO-01 and 78kg water;
(2) mixing and emulsifying: be added to by above-mentioned raw materials in emulsifying kettle, opens the mulser on emulsifying kettle, carries out emulsification 30 minutes; Observe emulsification situation, it is floating without oily that material reaches surface, is considered as emulsification complete;
(3) homogeneous: the emulsion of step (2) gained is added to high-shear homogenizer and carries out shear and homogenize; Start homogenizer, adjustment homogenizer feed pressure is no more than 10MPa, and observe adjustment pressure, pressure carries out homogeneous continuously to make it ensure; Reaching 8 ~ 10MPa timing at pressure to be switched in spraying metering kettle by material, the material before pressure does not reach at emulsifying kettle Inner eycle, until by whole for material homogeneous to spraying in still;
(4) spraying dry: spray after homogeneous, spraying starts water inlet spray, when temperature reaches 250 DEG C, start charging, controls outlet temperature at 90 DEG C ~ 120 DEG C, ensures temperature continuous feed; Control the charging rate of screw pump, wherein controlling screw pump voltage is 15V ~ 25V; Control water content≤10%, sampling detects;
(5) pack, put storage in storage.
Embodiment 3
Described CLA microcapsules, are made up of the raw material of following weight portion: CLA 25kg; Sex change food starch 25kg; Water 75kg.
The preparation method of described CLA microcapsules, comprises the following steps:
(1) raw material preparation: take 26kg CLA respectively, denaturation cornstarch that 26kg specifications and models are CO-01 and 78kg water;
(2) mixing and emulsifying: be added to by above-mentioned raw materials in emulsifying kettle, opens the mulser on emulsifying kettle, carries out emulsification 30 minutes; Observe emulsification situation, it is floating without oily that material reaches surface, is considered as emulsification complete;
(3) homogeneous: the emulsion of step (2) gained is added to high-shear homogenizer and carries out shear and homogenize; Start homogenizer, adjustment homogenizer feed pressure is no more than 10MPa, and observe adjustment pressure, pressure carries out homogeneous continuously to make it ensure; Reaching 8 ~ 10MPa timing at pressure to be switched in spraying metering kettle by material, the material before pressure does not reach at emulsifying kettle Inner eycle, until by whole for material homogeneous to spraying in still;
(4) spraying dry: spray after homogeneous, spraying starts water inlet spray, when temperature reaches 250 DEG C, start charging, controls outlet temperature at 90 DEG C ~ 120 DEG C, ensures temperature continuous feed; Control the charging rate of screw pump, wherein controlling screw pump voltage is 15V ~ 25V; Control water content≤10%, sampling detects;
(5) pack, put storage in storage.
Claims (6)
1. CLA microcapsules, is characterized in that, are made up of following raw material: CLA, sex change food starch and water; Wherein CLA by weight: sex change food starch: water is 1:1:3.
2. CLA microcapsules according to claim 1, is characterized in that, be made up of the raw material of following weight portion: CLA 23 ~ 26 parts; Sex change food starch 23 ~ 26 parts; 69 ~ 78 parts, water.
3. CLA microcapsules according to claim 1, is characterized in that, be made up of the raw material of following weight portion: CLA 25 parts; Sex change food starch 25 parts; 75 parts, water.
4. a preparation method for CLA microcapsules described in claim 1, comprises the following steps:
(1) raw material preparation: take CLA, sex change food starch and water respectively; Wherein CLA by weight: sex change food starch: water is 1:1:3;
(2) mixing and emulsifying: above-mentioned raw materials is added in emulsifying kettle and carries out fully emulsifiedly obtaining emulsion, wherein emulsification 30 minutes;
(3) homogeneous: the emulsion of step (2) gained is added to high-shear homogenizer and carries out shear and homogenize; Adjustment homogenizer feed pressure is no more than 10MPa, ensures that pressure carries out homogeneous continuously; Reaching 8 ~ 10MPa timing at pressure to be switched in spraying metering kettle by material, the material before pressure does not reach at emulsifying kettle Inner eycle, until by whole for material homogeneous to spraying in still;
(4) spraying dry: spray after homogeneous, spraying starts water inlet spray, when temperature reaches 250 DEG C, start charging, controls outlet temperature at 90 DEG C ~ 120 DEG C, ensures temperature continuous feed; Control the charging rate of screw pump, wherein controlling screw pump voltage is 15V ~ 25V; Control water content≤10%, sampling detects;
(5) pack, put storage in storage.
5. the preparation method of CLA microcapsules according to claim 4, is characterized in that, in described step (1), sex change food starch is denaturation cornstarch.
6. the preparation method of CLA microcapsules according to claim 5, it is characterized in that, the specifications and models of described denaturation cornstarch are CO-01.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510560683.0A CN105077249B (en) | 2015-09-06 | 2015-09-06 | A kind of CLA microcapsules and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510560683.0A CN105077249B (en) | 2015-09-06 | 2015-09-06 | A kind of CLA microcapsules and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105077249A true CN105077249A (en) | 2015-11-25 |
| CN105077249B CN105077249B (en) | 2018-03-16 |
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| CN201510560683.0A Active CN105077249B (en) | 2015-09-06 | 2015-09-06 | A kind of CLA microcapsules and preparation method thereof |
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| CN106072517A (en) * | 2016-06-08 | 2016-11-09 | 青岛尚医制药有限公司 | A kind of diet food and preparation technology thereof |
| CN106578141A (en) * | 2016-12-20 | 2017-04-26 | 乌鲁木齐上善元生物科技有限公司 | Conjugated linoleic acid microcapsule and preparation method thereof |
| CN109090613A (en) * | 2018-07-13 | 2018-12-28 | 大连医诺生物股份有限公司 | A kind of conjugated linoleic acid glyceride microcapsule powder and preparation method thereof |
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| CN105077249B (en) | 2018-03-16 |
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