CN105067545A - Disinfectant concentration detection method and concentration monitoring device using method - Google Patents

Disinfectant concentration detection method and concentration monitoring device using method Download PDF

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CN105067545A
CN105067545A CN201510492996.7A CN201510492996A CN105067545A CN 105067545 A CN105067545 A CN 105067545A CN 201510492996 A CN201510492996 A CN 201510492996A CN 105067545 A CN105067545 A CN 105067545A
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thimerosal
concentration
reaction tube
test fluid
disinfectant
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CN105067545B (en
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李应顺
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Guangzhou Is Along First Medical Devices Co Ltd
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Guangzhou Is Along First Medical Devices Co Ltd
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Abstract

The invention discloses a disinfectant concentration detection method and a concentration monitoring device using the method. According to the disinfectant concentration detection method, a disinfectant stock solution is sucked quantitatively from a disinfectant storage tank through a quantitative disinfectant sampling device arranged on the concentration monitoring device using the method, the light absorbance of the disinfectant stock solution is detected, water is sucked from a water feed port into a reaction tube, a disinfectant sample with diluted concentration is prepared, the light absorbance of the disinfectant sample is detected and recorded, a corresponding standard curve is drawn, a disinfection machine is started and automatically sucks the disinfectant in use into the reaction tube, the light absorbance is detected through a detector, then judgment results are compared by a machine, the whole process is automatically completed by the machine, real-time monitoring is realized, the concentration monitoring accuracy is greatly improved, disinfection failure caused by insufficient concentration of the disinfectant is avoided, time and labor are saved, the manufacturing cost is low, and the disinfectant concentration detection method and the concentration monitoring device are applicable to the field of disinfection instruments.

Description

The concentration monitoring device of a kind of thimerosal concentration detection method and use the method
Technical field
The present invention relates to disinfecting apparatus field, particularly relate to the concentration monitoring device of a kind of thimerosal concentration detection method and use the method.
Background technology
At present, medical endoscope all will carry out cleaning and sterilizing after each could be used for next patient, and cleaning and sterilizing generally adopts artificial disinfection way or endoscope cleaning-disinfection machine sterilization automatically.The step of one of them key uses medicining liquid dipping a period of time, to kill the contaminating microorganisms be attached on scope, to avoid patient's cross-infection.Disinfection Effect is relevant with action time with thimerosal concentration, therefore will ensure qualified Disinfection Effect, must use the thimerosal of normal concentration and act on more than official hour.Some thimerosal is disposable, and has a class thimerosal can repeatedly Reusability.The sterilizing endoscope liquid that Hospitals at Present is conventional has glutaraldehyde, o-phthalaldehyde(OPA) etc., and glutaraldehyde and o-phthalaldehyde(OPA) are more stable when packing, and can deposit and not lose efficacy for more than 1 year, but after unpacking uses, its term of validity generally only has about 15 days.Glutaraldehyde and o-phthalaldehyde(OPA) are can reusable thimerosal, the standard program of endoscope cleaning sterilization is generally flushing → enzyme washes → cleans → sterilize → rinsing → dry up, therefore the water that in a small amount of scope and pipeline, previous step is residual can be all mixed into when thimerosal uses at every turn, thimerosal is diluted, and concentration can constantly decline.Therefore the concentration of often monitoring thimerosal is in use needed, ensure in specialized range, the Disinfection Effect that guarantee is qualified, when thimerosal concentration drops to certain value, general glutaral disinfectant solution inefficacy concentration is about 90% of original concentration, the inefficacy concentration of o-phthalaldehyde(OPA) is about 65% of original concentration, just can not ensure Disinfection Effect, therefore needs to carry out concentration monitor to the thimerosal in use.
The monitoring means generally adopted at present to be immersed in thimerosal 2 seconds with Test paper (colour developing card) taking-up afterwards drains, and develops the color in 5 to 8 minutes and carry out colorimetric with standard color version, judge that whether thimerosal concentration is qualified by naked eyes.Hospitals at Present is usually used in thimerosal glutaraldehyde, the method for o-phthalaldehyde(OPA) concentration monitor adopts test paper (colour developing card) colour developing, the method for naked eyes and standard color version colorimetric.This method needs manual operation, carries out colorimetric at the appointed time, artificial interpretation, and the color difference that test paper shows within the scope of finite concentration is not obvious, and resultant error is comparatively large, and wastes time and energy.The color of the colour developing card display of general glutaraldehyde is yellow, and the color of the colour developing card display of o-phthalaldehyde(OPA) is purple, two kinds of color distinction are very large, and then very high to the requirement of detecting device to the color being suitable for automatic interpretation two kinds of Different lightwaves long on a machine, machine cost is expensive.
Although existing many sections of bibliographical informations can adopt ultraviolet absorption method directly to test the concentration of glutaraldehyde simply now, but find through actual test, ultraviolet absorption method is only effective to the senaside of storing state (steady state (SS)), and actual use is generally alkaline glutaric dialdehyde, need before use to add pH adjusting agent.Alkaline glutaric dialdehyde is unstable, meeting polymerization reaction take place, this is also the shorter reason of the glutaraldehyde term of validity after using, and the rate of absorbing UV of alkaline glutaric dialdehyde is constantly change in time, therefore ultraviolet absorption method be not suitable for and carry out concentration monitor to the glutaral disinfectant solution in using.
Summary of the invention
For solving the problem, the invention provides a kind of thimerosal concentration detection method adopting pairing comparision to detect thimerosal concentration and the concentration monitoring device automatically detecting thimerosal concentration in sterilizing machine.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of thimerosal concentration detection method, comprises the following steps:
A), at least prepare the thimerosal of two kinds of concentration, detect the absorbance of each concentration thimerosal;
B), the absorbance of each concentration and correspondence is drawn the typical curve being used for concentration calibration accordingly;
C) absorbance of thimerosal sample, is detected;
D) absorbance, by thimerosal sample recorded and typical curve contrast, the relative concentration of the liquid sample that is sterilized.
Be further used as the improvement of technical solution of the present invention, in step c), after thimerosal sample mixes with test fluid, adopt photoelectric colorimetry to record absorbance.
A kind of thimerosal concentration detection method that uses carries out the concentration monitoring device of monitoring, comprise the thimerosal storage box of placing thimerosal and the reaction tube detecting sample for the preparation of thimerosal, the export pipeline of reaction tube is provided with the detecting device for detecting thimerosal absorbance, reaction tube is provided with water inlet, is provided with for quantitatively extracting the thimerosal quantitative sampling device of thimerosal to reaction tube between reaction tube and thimerosal storage box.
Be further used as the improvement of technical solution of the present invention, reaction tube is also connected with the test fluid bottle that test fluid is housed, and is provided with for quantitatively extracting the test fluid quantitative sampling device of test fluid to reaction tube between reaction tube and test fluid bottle.
Be further used as the improvement of technical solution of the present invention, the porch of thimerosal quantitative sampling device connects into the mouth of a river, and thimerosal quantitative sampling device is provided with escape hole, and escape hole is back to thimerosal storage box.
Be further used as the improvement of technical solution of the present invention, the outer wall of reaction tube is provided with the temperature sensor of heating arrangement for heating and control temperature, the air pump I be provided with for drying up reaction tube or mixing material of reaction tube.
Be further used as the improvement of technical solution of the present invention, thimerosal quantitative sampling device and test fluid quantitative sampling device adopt ram pump.
Be further used as the improvement of technical solution of the present invention, thimerosal quantitative sampling device and test fluid quantitative sampling device adopt quantity tube.
Be further used as the improvement of technical solution of the present invention, the air pump III entering quantity tube II for blow pressure test fluid that test fluid quantitative sampling device comprises quantity tube II and is provided with on test fluid bottle, quantity tube II is provided with liquid level sensor.
Be further used as the improvement of technical solution of the present invention, thimerosal quantitative sampling device is provided with quantity tube I, and quantity tube I is provided with the liquid pump for extracting thimerosal.
Beneficial effect of the present invention: this thimerosal concentration detection method and the thimerosal quantitative sampling device using the concentration monitoring device of the method to be provided with quantitatively extract thimerosal stoste to reaction tube from thimerosal storage box, detect the absorbance of thimerosal stoste, water is extracted to reaction tube from water inlet, the thimerosal sample copy of prepared and diluted concentration, detect the absorbance of thimerosal sample, record and draw corresponding typical curve, when sterilizing machine runs, thimerosal during Automatic Extraction uses is to reaction tube, absorbance is detected by detecting device, then sentence read result is contrasted by machine, whole process can be completed automatically by machine, Real-Time Monitoring, greatly improve the accuracy of concentration monitor, avoid the sterilization failure caused because thimerosal concentration is not enough, time saving and energy saving and low cost of manufacture.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the invention will be further described:
Fig. 1 is first embodiment of the invention one-piece construction schematic diagram;
Fig. 2 is second embodiment of the invention one-piece construction schematic diagram;
Fig. 3 is linear graph formed by glutaral disinfectant solution A brand absorbance of the present invention and concentration;
Fig. 4 is linear graph formed by o-phthalaldehyde(OPA) thimerosal B brand absorbance of the present invention and concentration;
Fig. 5 is linear graph formed by o-phthalaldehyde(OPA) thimerosal C brand absorbance of the present invention and concentration;
Fig. 6 is linear graph formed by o-phthalaldehyde(OPA) thimerosal D brand absorbance of the present invention and concentration.
Embodiment
Be clearly and completely described below with reference to embodiment and the accompanying drawing technique effect to design of the present invention, concrete structure and generation, to understand object of the present invention, characteristic sum effect fully.Obviously; described embodiment is a part of embodiment of the present invention, instead of whole embodiment, based on embodiments of the invention; other embodiments that those skilled in the art obtains under the prerequisite not paying creative work, all belong to the scope of protection of the invention.
With reference to Fig. 1 ~ Fig. 6, the present invention is a kind of thimerosal concentration detection method, comprises the following steps:
A), at least prepare the thimerosal of two kinds of concentration, detect the absorbance of each concentration thimerosal;
B), the absorbance of each concentration and correspondence is drawn the typical curve being used for concentration calibration accordingly;
C) absorbance of thimerosal sample, is detected;
D) absorbance, by thimerosal sample recorded and typical curve contrast, the relative concentration of the liquid sample that is sterilized.
As the preferred embodiment of the present invention, in step c), after thimerosal sample mixes with test fluid, photoelectric colorimetry is adopted to record absorbance.
As the preferred embodiment of the present invention, in step a), the thimerosal concentration of configuration comprises containing the thimerosal of volume fraction 100% sterilized stock solution and is the thimerosal of 50% sterilized stock solution containing volume fraction.
Can the absorbance index of multiple variable concentrations, drawing standard curve, concentration range is 1% ~ volume fraction in volume fraction is in 100%.
A kind of thimerosal concentration detection method that uses carries out the concentration monitoring device of monitoring, comprise the thimerosal storage box 1 of placing thimerosal and the reaction tube 2 detecting sample for the preparation of thimerosal, the export pipeline of reaction tube 2 is provided with the detecting device 4 for detecting thimerosal absorbance, reaction tube 2 is provided with water inlet 21, is provided with for quantitatively extracting the thimerosal quantitative sampling device of thimerosal to reaction tube 2 between reaction tube 2 and thimerosal storage box 1.
This thimerosal concentration detection method and the thimerosal quantitative sampling device using the concentration monitoring device of the method to be provided with quantitatively extract thimerosal stoste to reaction tube 2 from thimerosal storage box 1, detect the absorbance of thimerosal stoste, water is extracted to reaction tube 2 from water inlet 21, the thimerosal sample copy of prepared and diluted concentration, detect the absorbance of thimerosal sample, record and draw corresponding typical curve, when sterilizing machine runs, thimerosal during Automatic Extraction uses is to reaction tube 2, absorbance is detected by detecting device 4, then sentence read result is contrasted by machine, whole process can be completed automatically by machine, Real-Time Monitoring, greatly improve the accuracy of concentration monitor, avoid the sterilization failure caused because thimerosal concentration is not enough, time saving and energy saving and low cost of manufacture.
As the preferred embodiment of the present invention, reaction tube 2 is also connected with the test fluid bottle 3 that test fluid is housed, and is provided with for quantitatively extracting the test fluid quantitative sampling device of test fluid to reaction tube 2 between reaction tube 2 and test fluid bottle 3.
As the preferred embodiment of the present invention, the porch of thimerosal quantitative sampling device connects into the mouth of a river 21, and thimerosal quantitative sampling device is provided with escape hole 8, and escape hole 8 is back to thimerosal storage box 1.
As the preferred embodiment of the present invention, the outer wall of reaction tube 2 is provided with the temperature sensor 24 of heating arrangement 22 for heating and control temperature, the air pump I 7 be provided with for drying up reaction tube 2 or mixing material of reaction tube 2.
Heating arrangement 22 is for adding thermosticking film.
As the preferred embodiment of the present invention, thimerosal quantitative sampling device and test fluid quantitative sampling device adopt ram pump 5.
Ram pump 5 front end of thimerosal quantitative sampling device is provided with retaining valve.
As the preferred embodiment of the present invention, thimerosal quantitative sampling device and test fluid quantitative sampling device adopt quantity tube.
As the preferred embodiment of the present invention, the air pump III 31 entering quantity tube II 62 for blow pressure test fluid that test fluid quantitative sampling device comprises quantity tube II 62 and is provided with on test fluid bottle 3, quantity tube II 62 is provided with liquid level sensor 64.
Quantity tube II and test fluid bottle 3 are provided with air strainer.
As the preferred embodiment of the present invention, thimerosal quantitative sampling device is provided with quantity tube I 61, and quantity tube I 61 is provided with the liquid pump 63 for extracting thimerosal.
As the preferred embodiment of the present invention, reaction tube 2 be provided with blow vent 23.
As the preferred embodiment of the present invention, detecting device 4 is photo-diode pipe detector.Detecting device 4 is also provided with conductivity sensor.
The present invention and automatic endoscope cleaning-disinfection machine supporting, for the concentration of glutaraldehyde in monitoring machinery or o-phthalaldehyde(OPA).The invention provides a kind of test fluid, after mixing with quantitative thimerosal, be incubated colour developing, so adopt the method for photoelectric colorimetry by machine interpretable result, greatly improve the accuracy of concentration monitor, avoid the sterilization failure caused because thimerosal concentration is not enough.Whole process can be completed automatically by machine, time saving and energy saving.
The light absorption detecting device of test fluid Same Wavelength can be applicable to glutaraldehyde and o-phthalaldehyde(OPA) two kinds of thimerosals simultaneously, and the manufacturing cost of detecting device is much lower.The glutaraldehyde of several brands common in test fluid and market and o-phthalaldehyde(OPA) thimerosal sample are tested, result display all can carry out chromogenic reaction to them.Generate the product of transparent colour generation after reacting with glutaraldehyde, light absorption can be produced to the light in a wavelength range; More shallow with o-phthalaldehyde(OPA) reaction product color, but its reaction product can assemble formation colloidal solution, all has absorption to the light of different wave length.Therefore adopt the light source of Same Wavelength to detect simultaneously, do not need to use the filtering apparatus such as grating, the laser diode only need commonly used is as light source.By the absorbance result of test fluid to the thimerosal example reaction product of several different brands, the absorbance that display different brands thimerosal produces is different, but its absorbance is all linear with its concentration within the scope of working concentration.Therefore, as long as when thimerosal brings into use concentration, machine is calibrated automatically, and namely the stoste of sampling two parts of volumes carries out detecting its concentration is 100%, writes down its absorbance; Get again a stoste add a water dilution and concentration be 50% sample detect, write down its absorbance.These two data points are drawn a straight line, namely obtains the typical curve of concentration calibration.The absorbance record the thimerosal sample after using and typical curve contrast, and can learn its relative concentration declined, thus judge whether it lost efficacy.
The specific embodiment of the invention one:
Monitoring device is primarily of thimerosal quantitative sampling device and test fluid quantitative sampling device, reaction tube 2, detecting device 4, and some solenoid valves, a few part forms.Wherein the quantitative interpolation of two kinds of liquid is all completed by ram pump 5, ram pump 5 be a kind of flow can accurate quantification control precision pump.Thimerosal and test fluid are quantitatively input in reaction tube 2 respectively to be mixed, and reacts five minutes, then flow through detecting device 4 and detect under heating and thermal insulation condition, from colour developing degree of depth determination thimerosal concentration.
Under holding state, all solenoid valves are normally off.When starting during survey, T-valve 1 is first in upper left and leads to state, T-valve 7 17 is adjusted to the logical state in left and right, and start ram pump 5 and make thimerosal at pipeline inner circulating reflux in thimerosal storage box 1, object is thimerosal when first rinsing out residual last test in pipeline.Then the solenoid valve 2 12 of blow vent 23 is opened, T-valve 1 transfers lower-left to and leads to state, the ram pump 5 of thimerosal quantitative sampling device is controlled by a certain amount of by motherboard circuit, the thimerosal of two parts of volumes is injected in reaction tube 2 altogether, a certain amount of test fluid is injected reaction tube 2 by the ram pump 5 simultaneously controlling test fluid quantitative sampling device, all closes with latter two ram pump 5.Open solenoid valve 5 15, the air pump of intermittent start simultaneously I 7, makes a small amount of air be blown into from the bottom of reaction tube 2, plays and be fully uniformly mixed effect.Then shut electromagnetic valve 2 12, solenoid valve 5 15, starts heating arrangement 22, makes reaction tube 2 temperature maintain design temperature stop heating after five minutes by temperature sensor 24 FEEDBACK CONTROL heating power.Then open solenoid valve 2 12, solenoid valve 6 16, namely reactant liquor flows through detecting device 4, and when conductivity sensor detects that liquid is through out-of-date, detecting device 4 starts to record the data that record and thimerosal concentration is presented on machine display.Shut electromagnetic valve 2 12 subsequently, opens water intaking valve 13 to bottom right and leads to state, and reaction tube 2 and downstream line are rinsed in water inlet, within 10 seconds, closes water intaking valve 13 afterwards.Booster air pump I 7, opens solenoid valve 4 14, dries up reaction tube 2 and downstream line with air-flow, gets ready, then closes all parts, complete detection for detecting next time.
Due to different brands thimerosal contained by the kind of adjuvant and consumption different, may cause certain influence to the colour developing result of test fluid, the present invention creatively adopts the method detecting relative concentration to eliminate interference.After executing at endoscope cleaning-disinfection machine the step changing thimerosal at every turn, namely automatic calibration when new thimerosal is brought into use, first performs once above-mentioned standard detection, gets two parts of volume sterilization liquid and detects absorbance, and by detectable concentration outcome record in machine internal memory, be labeled as 100%; Perform 50% Concentration Testing again, namely by above-mentioned sequence of movement move to thimerosal is injected reaction tube 2 time, only inject a volume sterilization liquid, then T-valve 1 goes back to upper left and leads to state, T-valve 7 17 goes to upper right and leads to state, open water intaking valve 13 to lower-left and lead to state, start ram pump 5 to run a period of time and make to be full of water in pipeline, unnecessary water flows into freeing port, then T-valve 7 17 is closed, transfer T-valve 1 to lower-left and lead to state, mainboard controls ram pump 5 and injects the water of a volume to reaction tube 2, thus obtains the sample of 50% concentration.Then close T-valve 1, water intaking valve 13, continue to perform follow-up injection test fluid and the step such as insulation reaction, detection, detect the concentration results obtained and be also recorded in machine internal memory, be labeled as 50%.100% and 50% two data points are used for calibration draw a straight line, obtain typical curve.During each in this thimerosal life cycle monitoring, all detect by standard program and get two parts of volume sample, acquired results and typical curve are compared, and obtain a relative concentration values, send prompting message when the setting value of relative concentration lower than corresponding thimerosal.
The preferred embodiment of the present invention two:
Because ram pump 5 belongs to precision element, its price is high, the invention provides a kind of replacement scheme, adopts special quantity tube to replace ram pump 5 to realize quantitative liquid-filling function.As shown in Figure 2, wherein liquid pump 63 need adopt Miniature diaphragm pump to its structural principle, because membrane pump has the effect of retaining valve, can cancel retaining valve.
When test starts, T-valve 1 is in upper left and leads to state, start liquid pump 63, open T-valve 7 17 to left and right and lead to state, thimerosal circulation flushing is full of quantity tube I 61 simultaneously, then T-valve 1 and liquid pump 63 is closed, booster air pump II 81, open solenoid valve 8 18, with the thimerosal that air-flow blowout upper pipe is unnecessary, close T-valve 7 17 subsequently, open breather valve 12, T-valve 1 is forwarded to logical state up and down, thimerosal in quantity tube I 61 is injected reaction tube 2, close air pump II 81 subsequently, solenoid valve 8 18, T-valve 1, complete the sampling of a volume sterilization liquid, repeat once above everything, complete the injection of two parts of volume sterilization liquid samples.Test fluid is pressed in quantity tube II 62 by booster air pump III 31, when in quantity tube II 62, liquid level rises to liquid level sensor 64, close air pump III 31, open breather valve 10, test liquid level in quantity tube II 62 and lean on gravity reflux to inlet height thus complete quantitatively.Close breather valve 10 after five seconds, open solenoid valve 9 19, the test fluid in quantity tube II 62 is flowed in reaction tube 2, and then shut electromagnetic valve 9 19, completes the quantitative injection of test fluid.Below to add the everything such as thermal response and detection all identical with the first embodiment.Calibration actions when newly changing thimerosal is also similar with the first embodiment.Namely first perform by standard program and cancel venom action for twice and obtain two parts of volume sterilization liquid and carry out testing and obtain the data point that concentration is 100%, to rerun the calibration testing at a 50% concentration numbers strong point, namely the action once cancelling venom has first been run, after injecting a volume sterilization liquid, T-valve 1 goes back to upper left and leads to state, T-valve 7 17 goes to upper right and leads to state, water intaking valve 13 forwards lower-left to and leads to state and make quantity tube I 61 be full of water, then water intaking valve 13 is closed, booster air pump II 81, open solenoid valve 8 18, with the water that air-flow blowout upper pipe is unnecessary, close T-valve 7 17 subsequently, open solenoid valve 2 12, T-valve 1 is forwarded to logical state up and down, the water of volume a in quantity tube I 61 is injected reaction tube 2, close air pump II 81 subsequently, solenoid valve 8 18, T-valve 1, thus complete the sampling of 50% concentration thimerosal and continue follow-up detection calibration.
Certainly, the invention is not limited to above-mentioned embodiment, those of ordinary skill in the art also can make equivalent variations or replacement under the prerequisite without prejudice to spirit of the present invention, and these equivalent distortion or replacement are all included in the application's claim limited range.

Claims (10)

1. a thimerosal concentration detection method, is characterized in that, comprises the following steps:
A), at least prepare the thimerosal of two kinds of concentration, detect the absorbance of each concentration thimerosal;
B), the absorbance of each concentration and correspondence is drawn the typical curve being used for concentration calibration accordingly;
C) absorbance of thimerosal sample, is detected;
D) absorbance, by thimerosal sample recorded and typical curve contrast, the relative concentration of the liquid sample that is sterilized.
2. thimerosal concentration detection method according to claim 1, is characterized in that: in described step c), adopts photoelectric colorimetry to record absorbance after thimerosal sample mixes with test fluid.
3. one kind uses thimerosal concentration detection method described in claim 1 to carry out the concentration monitoring device of monitoring, it is characterized in that: comprise the thimerosal storage box (1) of placing thimerosal and the reaction tube (2) detecting sample for the preparation of thimerosal, the export pipeline of described reaction tube (2) is provided with the detecting device (4) for detecting thimerosal absorbance, described reaction tube (2) is provided with water inlet (21), is provided with for quantitatively extracting the thimerosal quantitative sampling device of thimerosal to reaction tube (2) between described reaction tube (2) and thimerosal storage box (1).
4. concentration monitoring device according to claim 3, it is characterized in that: described reaction tube (2) is also connected with the test fluid bottle (3) that test fluid is housed, being provided with between described reaction tube (2) and test fluid bottle (3) for quantitatively extracting the test fluid quantitative sampling device of test fluid to reaction tube (2).
5. concentration monitoring device according to claim 4, it is characterized in that: the porch of described thimerosal quantitative sampling device connects into the mouth of a river (21), described thimerosal quantitative sampling device is provided with escape hole (8), and described escape hole (8) is back to thimerosal storage box (1).
6. concentration monitoring device according to claim 4, it is characterized in that: the outer wall of described reaction tube (2) is provided with the temperature sensor (24) of heating arrangement (22) for heating and control temperature, the air pump I (7) be provided with for drying up reaction tube (2) or mixing material of described reaction tube (2).
7. according to concentration monitoring device described in any one in claim 4 ~ 6, it is characterized in that: described thimerosal quantitative sampling device and test fluid quantitative sampling device adopt ram pump (5).
8. according to concentration monitoring device described in any one in claim 4 ~ 6, it is characterized in that: described thimerosal quantitative sampling device and test fluid quantitative sampling device adopt quantity tube.
9. concentration monitoring device according to claim 8, it is characterized in that: the air pump III (31) entering quantity tube II (62) for blow pressure test fluid that described test fluid quantitative sampling device comprises quantity tube II (62) and is provided with on test fluid bottle (3), described quantity tube II (62) is provided with liquid level sensor (64).
10. concentration monitoring device according to claim 8, it is characterized in that: described thimerosal quantitative sampling device is provided with quantity tube I (61), described quantity tube I (61) is provided with the liquid pump (63) for extracting thimerosal.
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