CN105056004A - Traditional Chinese medicine composition for treating chloasma - Google Patents

Abstract

A traditional Chinese medicine composition for treating chloasma comprises an internal composition and an external composition. The internal composition comprises teasel root, Chinese angelica root, Szechuan lovage rhizome, safflower, dried longan, seed of Chinese dodder, kudzuvine root, motherwort, malt and glossy privet fruit. The external composition comprises stiff silkworm, giant Typhonium rhizome, Dahurian angelica root, borax, gypsum, sparrow drippings, talc, borneol and redroot gromwell root. The traditional Chinese medicine composition is externally and internally taken for combined use, is capable of adjusting the human body to a long-lasting, stable state with balanced yin and yang and smooth qi and blood, by regulating qi and activating blood, activating and harmonizing qi-blood, dredging the meridians, nourishing liver and kidney, and tonifying deficiency and strengthening healthy qi; thus the purpose of removing speckles, maintaining beauty, promoting blood circulation to dissipate stasis and beautifying face is achieved. The traditional Chinese medicine composition has ideal curative effect and low cost, a preparation method is simple and feasible and is widely applicable, and great social and economic benefits can be created.

Description

A kind of Chinese medicine composition for the treatment of chloasma

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of chloasma.

Background technology

Chloasma: chloasma is also known as " chloasma hepaticum ", and motherland's medical science is also called " chloasma " is that a kind of common limitation betiding facial area is filbert to auburn chromatopathy.Can be physiological or pathologic performance.Be more common in middle-aged women.Confirm mainly because all inducements (endocrine hormone Developmental and Metabolic Disorder, menoxenia, amenorrhea, chronic pelvic inflammatory disease, liver cirrhosis, chronic alcoholism, tuberculosis, senile chronic bronchitis, addison disease also with the microbial state treatment of medicine, cosmetics, daylight, nutrition and skin lesion) cause the impaired variation of melanin gene in human body through medical research, thus create a large amount of abnormal melanin, be deposited on skin base layer and formed.Be everlasting and increase the weight of spring and summer, autumn in winter alleviates.Primary disease men and women all can occur, more with women.Show as dark complexion, smoke black, dusty face, face traitor, chloasma hepaticum, the symptoms such as black speck of looking unfamiliar, affect patient's appearance for one is many because of property hyperpigmentary disorders, cause serious mental pressure to it.Prevalence is on the rise in recent years, gives much people's spirit of liking to be beautiful and in lifely cause great misery now.Chloasma belongs to dermatology common disease, and pathogenesis it be not immediately clear.Modern medicine is thought may be relevant with many factors such as endocrine disturbance, heredity, D&C, some chronic disease, ultraviolet excessive radiation.Wherein endocrine disturbance is primary pathogenic factors.Namely pigmented spots can be multiple at first, tend to merge form not of uniform size, irregular patch, are symmetrically distributed in the face exposing and expose.The most outstanding with cheekbone portion, forehead, two cheeks, sometimes in butterfly wing, occasionally in upper lip.Clear-cut margin or in diffusivity, local NIP and squama.No conscious sympton, pigment can slightly change with factors such as season, Exposure to Sunlight, hormonal changes, does not often prolongedly move back, and therefore, the medicine preventing and treating chloasma improving a kind of highly effective and safe has become the urgent needs of people.

Summary of the invention

The invention provides a kind of Chinese medicine composition for the treatment of chloasma, oral administration and externally is with the use of, treatment chloasma satisfactory effect.

The technical scheme adopted is :treat a Chinese medicine composition for chloasma, its by taking orally, external two groups of compositionss form; In its internal composition, the parts by weight of each crude drug are: Radix Dipsaci 20-35 parts, Radix Angelicae Sinensis 20 1 35 parts, Rhizoma Chuanxiong 10 1 20 parts, 10 1 20 parts, Flos Carthami, Arillus Longan 10 1 20 parts, Semen Cuscutae, 10 1 20 parts, Radix Puerariae 10 1 20 parts, Herba Leonuri 10 1 20 parts, 10 1 20 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 10 1 15 parts;

In its topical composition, the parts by weight of each crude drug are: Bombyx Batryticatus 10 1 20 parts, Rhizoma Typhonii 10 1 20 parts, the Radix Angelicae Dahuricae 10 1 20 parts, Borax 10 1 20 parts, 15 1 30 parts, Gypsum Fibrosum, Faeces Passeris 10 1 18 parts, 15 1 30 parts, Talcum, Borneolum Syntheticum 3 one 10 parts, Radix Arnebiae (Radix Lithospermi) 10 1 15 parts.

Each crude drug mechanism in the present invention:

Radix Dipsaci: invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, only metrorrhagia, its bitter in the mouth pained with it and weighing, therefore blood system can be entered, blood circulation regulating, detumescence poison, tonifying liver, bone and muscle strengthening, determine meridians, only in warp, (muscles and bones) is ached, antiabortive, control married woman leucorrhea, tissue regeneration promoting blood, removing blood stasis with potent drugs blood, fall stillborn fetus, cough-relieving is coughed hemoptysis, controls red white turbid urine.Modern pharmacological research: 1. vitamin antagonist E deficiency disease: through white mice and chicken test, prove that Radix Dipsaci has the effect of vitamin antagonist E deficiency disease.2. hemostasis, analgesic activity: effect carbuncle and ulcer being had to evacuation of pus, hemostasis, analgesia, promotion tissue regeneration.

Radix Angelicae Sinensis: Shennong's Herbal: sweet, pungent, warm.Return liver, the heart, spleen, large intestine channel.Compendium of Material Medica " intestine moistening stomach muscles and bones skin, control carbuncle, evacuation of pus pain relieving, and blood is enriched blood " its sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, and invigorating middle warmer has, has benefit, the gas medicine in sincere blood, the panacea also in blood in row.Chemical composition and pharmacological action: this product is rich in volatile ingredient, organic acid, saccharide, vitamin, aminoacid, inorganic elements, alkaline components and the composition such as stigmasterol, sitosterol, have and promote hemoglobin and erythrocytic generation, alleviate peripheral blood vessel smooth muscle clonic spasm of the muscle, increase blood flow, improve peripheral circulation, antithrombotic, analgesia, antiinflammatory, strengthens immunologic function.There is reduction myocardial oxygen consumption, have and reduce myocardial ischemia, scarce sugar, anoxia functions, promote non-specific immunity, improve microcirculation.

Rhizoma Chuanxiong: acrid in the mouth; Warm in nature, Gui Jing: return liver, gallbladder, pericardium channel; Materia Medica of Decoction blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Chemical composition: containing ligustrazine modern study: can expand crown and blood vessel to the effect Rhizoma Chuanxiong Aqueous extracts of coronary circulation and alkaloid thereof, increases coronary flow, improves myocardial ischemia situation.And have substantial connection with intracellular metabolism.Ligustrazine is improved erythrocyte and platelet surface electric charge, reduces blood viscosity, improves hemorheology effect.Also find that ligustrazine has urokinase effect, can direct plasminogen activation, but without fibrinolytic.Perlolyrine can make cAMP content in mice plasma increase, therefore can cause affecting cellular metabolism, increases the effects such as physiological function.

Flos Carthami: Compendium of Material Medica: invigorate blood circulation, moisturizes, pain relieving, loose swollen, stimulates the menstrual flow.Containing pigment that is red and yellow, be therefrom separated and obtain: carthamin, front carthamin, safflower yellow A and B [1-3], the bright glycoside of Flos Carthami.Again containing polyphenol components, alabastrum contains luteolin-7-O-glycoside, cholesterol, stigmasterol, cupreol, lauric acid, myristic acid, Palmic acid, linoleic acid, stearic acid, arachidic acid.Effect: invigorating blood circulation can be through, stasis-dispelling and pain-killing." Amplification on Materia Medica addendum ": Flos Carthami, broken stagnant blood, nourishes blood.Multiplex then removing blood stasis is few with then nourishing blood.Treatment macular eruption being dark-purple, improves blood circulation.

Arillus Longan: reinforcing the heart spleen, replenishing QI and blood, tranquilizing mind deficiency of both the heart and spleen, palpitation with fear caused by insufficiency of vital energy and blood, palpitation with a distress feeling, insomnia, forgetful, blood deficiency and yellow complexion, to have through uncomfortable, metrorrhagia.

Semen Cuscutae: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.Suffer from a deficiency of the kidney and rush down for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen, externally treating leucoderma.Performance: sweet in the mouth, warm in nature.Can by kidney controlling nocturnal emission with astringent drugs, nourishing the liver to improve visual acuity, antidiarrheal, antiabortive.For impotence due to deficiency of the kidney, seminal emission frequent micturition, leukorrhagia, lumbago, deficiency of the liver and kindey, blurring of vision, visual deterioration, weakness of the spleen and kidney, suffer from diarrhoea in loose stool, Liver and kidney is deficient, frequent fetal movement.The effect of Endocrine has report to point out, Semen Cuscutae water extract, to female rats gavage, can increase the weight in anterior pituitary of rat, ovary and uterus, but on lutropin in blood plasma (LH) level without impact; Rat ovary HCG/LH receptor number is increased, and Ka value more then decreases with matched group.Semen Cuscutae water extract is to ovariectomized female rats gavage, removal ovary anesthetized rat hypophysis can be improved to injection luteinizing hormone releasing hormone (LRH) LH secretory reaction afterwards, its plasma LH levels is to inject latter 90 minutes for the highest, 241.58%. can be improved therefore, reporter thinks, Semen Cuscutae can increase hypothalamic-pituitary-ovarian and urge luteal function, this effect is not the secretion due to their direct Stimulation of Pituitary Gland metakentrin, but owing to improve hypophysis to LRH and ovary to the reactivity of LH.

Radix Puerariae: sweet in the mouth, pungent, property is put down, and returns spleen, stomach, lung, urinary bladder channel.Expelling pathogenic factors from muscles for reducing heat, deliver examine, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.Main fever caused by exogenous pathogens, rigidity pain on the head and nape, measles from the beginning of, rash go out smooth, epidemic febrile disease is thirsty, diabetes, have loose bowels, dysentery, hypertension, coronary heart disease.Being rich in highly active isoflavone in Radix Puerariae can effective endocrine regulation.The exquisiteness that whole skin significantly becomes, lubrication, glossy, skin elasticity increase, macule skin ulcer pox reduce gradually and disappear, face wrinkles obviously reduces.

Fructus Hordei Germinatus: help digestion, and in, the therapeutic method to keep the adverse QI flowing downwards.Control food stagnation not disappear, distension and fullness in the abdomen, inappetence, vomiting is had loose bowels, and mammary swelling does not disappear.The southern regions of the Yunnan Province book on Chinese herbal medicine ": alleviating distention in middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, anti-nausea, disappear dyspepsia, only acid regurgitation acid regurgitation, antidiarrheal, the wide diaphragm of the stomach that disappears, and control married woman's milk breast and do not receive, and milk is more than.This product rich in vitamin E, has skin elasticity to increase, the effect of supply skin nutrient, adjustment carbohydrate metabolism.

Fructus Ligustri Lucidi: invigorating the liver and kidney, strong waist knee joint.Control yin asthenia generating intrinsic heat, dizzy, order flower, tinnitus, soreness of the waist and knees, early whitening of beard and hair.Nourishing the liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.1. " herbal classic ": " main invigorating middle warmer, settling five organs support spirit, except hundred diseases.Clothes fertilizer of a specified duration is strong." 2. " book on Chinese herbal medicine covers bamboo fish trap ": " black palpus of hair color, strong rigidity of soft tissues power, takes wind of enriching blood more." 3. " detailed outline ": " reinforcing YIN-essence, strong waist knee joint, improving eyesight." 4. " Bencao Jingshu ": " removing heat from blood, beneficial blood ".

Herba Leonuri: nature and flavor cold nature, bitter in the mouth, pungent.Function cures mainly " baking hole, soldier hole flies to warm up " (skin scabies part, macule, scabies, eczema), " holding together pump " (edema), " holding together cattle " (the puckery pain of urine heat), " Na Le emits sand " (menoxenia, dysmenorrhea, amenorrhea).Promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria, acute nephritis edema, there is obvious platelet aggregation inhibitory activity.In addition also have antithrombus formation, improve the effects such as coronary artery circulation, cardioprotection, blood pressure lowering, antibacterial, diuresis.

Above crude drug all can buy from common pharmacy, and its specification meets national medical standards.

Oral administration and externally of the present invention with the use of, by vital energy regualting and blood circulation-promoting, adjust smooth QI and blood, dredging the meridian, hold concurrently with nourishing the liver and kidney, tonify deficiency righting makes human body adjust to the unobstructed state of lasting, stable equilibrium between yin and yang, QI and blood.Thus reach spot-removing beautifying face, invigorating blood circulation addiction, beautify the object of appearance.Therapeutic effect is more satisfactory, and cheap, and preparation method is simple and easy to do, uses crowd wide, can create good social benefit and economic benefit.The present invention mainly identifies and corrects the principle treated according to Chinese medicine, collect many doctor chiefs, in conjunction with the strange medicine wonderful recipe that local Hong Lian temple Taoist Qiao Ming develops, skims the cream off milk; Based on Chinese medicine to pathogenetic understanding of facial colour spot and Therapeutic Principle, reference is Chinese medicine pharmacological research achievement at all times, the natural Chinese medicine of screening inrigorating qi and promoting blood circulation, tonifying Qi and lifting yang, dispersing the stagnated live-QI to relieve the stagnation of QI, suppressing the hyperactive liver and subsiding YANG, enriching yin and nourishing kidney, heat-clearing and toxic substances removing, clearing away heat-fire, strengthening vital QI to eliminate pathogenic factors, purging FU-organs lets out poison, and Huoxue San " is tired, regulates the metabolism function of human body, improve blood circulation of human body and liver detoxification ability, and form through the clinical practice summary of long-term diagnosis and treatment case.The cause of disease of the functional disorders such as the existing obvious endocrine of the generation due to primary disease, nervous system or digestive system can be followed, the chemical factors being subject to again many external worlds, as the impact of Exposure to Sunlight, thermal radiation, wound (scratch, friction etc.), contact photosensitizer or compound, the agent of external silvery, mercurial etc., therefore generally advocates treatment of the inside combined with the outside.This pathogenetic endogenous cause of ill with liver,spleen,kidney three is dirty and QI-blood circulation not normal in close relations, therefore treatment by oral administration of medicines internal organs many from liver spleen kidney by controlling.

Radix Dipsaci in side of the present invention, when being classified as monarch drug, wherein Radix Dipsaci invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Tissue regeneration promoting blood, removing blood stasis with potent drugs blood, modern pharmacological research has vitamin antagonist E deficiency disease; Radix Angelicae Sinensis and blood are enriched blood, its sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, and invigorating middle warmer has, benefit is had in row, gas medicine in sincere blood, the panacea also in blood, is rich in volatile ingredient, organic acid, saccharide, vitamin, aminoacid, inorganic elements, has promotion hemoglobin and erythrocytic generation, improve peripheral circulation, two medicines make liver spleen essence and blood fill, punching appoints tune smooth, can adjust and reach QI and blood, and happy feelings will body is good for face and is moistened as monarch.Herba Leonuri, Flos Carthami are ministerial drug, wherein Herba Leonuri promoting blood flow to regulate menstruation, inducing diuresis to remove edema, also have antithrombus formation in addition, improve the effects such as coronary artery circulation, cardioprotection, blood pressure lowering, antibacterial, diuresis.Flos Carthami is invigorated blood circulation, moisturize, pain relieving, loosely to swell, stimulate the menstrual flow, and treatment macular eruption being dark-purple, improves blood circulation.Assist monarch drug to strengthen to nourish blood, tune reaches QI and blood and act as minister.Arillus Longan reinforcing the heart spleen, replenishing QI and blood, tranquilizing mind deficiency of both the heart and spleen, the palpitation with fear caused by insufficiency of vital energy and blood, palpitation with a distress feeling, insomnia, forgetful, blood deficiency and yellow complexion, have through uncomfortable, metrorrhagia.Semen Cuscutae nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, for assistant make it use, Radix Puerariae, expelling pathogenic factors from muscles for reducing heat, deliver examine, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.Being rich in highly active isoflavone in Radix Puerariae can effective endocrine regulation.The exquisiteness that whole skin significantly becomes, lubrication, glossy, skin elasticity increase, macule skin ulcer pox reduce gradually and disappear, face wrinkles obviously reduces.Fructus Hordei Germinatus rich in vitamin E, has skin elasticity to increase, the effect of supply skin nutrient.Regulate carbohydrate metabolism.Fructus Ligustri Lucidi invigorating the liver and kidney, strong waist knee joint.Control yin asthenia generating intrinsic heat, early whitening of beard and hair.Nourishing the liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision, " removing heat from blood, beneficial blood.Above-mentioned three medicines help monarch to strengthen invigorating the liver and kidney, blood circulation regulating; Tissue regeneration promoting blood, adjust and reach QI and blood, the effect of happy feelings will, helps minister with promoting blood flow to regulate menstruation, improves blood circulation and makes QI-blood circulation unimpeded for making it use.Full side's invigorating the liver and kidney, strengthening the spleen, blood circulation regulating makes liver spleen essence and blood fill, punching appoints tune smooth, can adjust and reach QI and blood, happy feelings will.Strengthening vital QI to eliminate pathogenic factors, purging FU-organs lets out poison, Huoxue San " is tired, regulates the metabolism function of human body, improves blood circulation of human body and liver detoxification ability, the exquisiteness that skin significantly becomes, lubrication, glossy, skin elasticity increase, macule skin ulcer pox reduces gradually and disappears and reaches the effect of the light speckle of speckle removing, and because the sick position of primary disease is at skin, therefore coordinates the method for external treatment that medicine can be made to go directly focus, treating both the principal and secondary aspects of a disease, thus play better therapeutical effect.Total effective rate is 89.58%.

Detailed description of the invention

Embodiment 1, a kind of Chinese medicine composition for the treatment of chloasma, its by taking orally, external two groups of compositionss form; In its internal composition, the parts by weight of each crude drug are: Radix Dipsaci 30 parts, Radix Angelicae Sinensis 30 parts, Rhizoma Chuanxiong 15 parts, 15 parts, Flos Carthami, Arillus Longan 16 parts, Semen Cuscutae 16 parts, Radix Puerariae 15 parts, Herba Leonuri 15 parts, 15 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 15 parts; In its topical composition, the parts by weight of each crude drug are: Bombyx Batryticatus 10 parts, Rhizoma Typhonii 10 parts, the Radix Angelicae Dahuricae 10 parts, Borax 10 parts, 18 parts, Gypsum Fibrosum, Faeces Passeris 18 parts, 15 parts, Talcum, Borneolum Syntheticum 10 parts, Radix Arnebiae (Radix Lithospermi) 10 parts.

Embodiment 2, a kind of Chinese medicine composition for the treatment of chloasma, its by taking orally, external two groups of compositionss form; In its internal composition, the parts by weight of each crude drug are: Radix Dipsaci 35 parts, Radix Angelicae Sinensis 35 parts, Rhizoma Chuanxiong 20 parts, 20 parts, Flos Carthami, Arillus Longan 20 parts, Semen Cuscutae 20 parts, Radix Puerariae 20 parts, Herba Leonuri 20 parts, 20 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 12 parts; In its topical composition, the parts by weight of each crude drug are: Bombyx Batryticatus 15 parts, Rhizoma Typhonii 15 parts, the Radix Angelicae Dahuricae 15 parts, Borax 15 parts, 30 parts, Gypsum Fibrosum, Faeces Passeris 9 parts, 22 parts, Talcum, Borneolum Syntheticum 7 parts, Radix Arnebiae (Radix Lithospermi) 15 parts.

Embodiment 3, a kind of Chinese medicine composition for the treatment of chloasma, its by taking orally, external two groups of compositionss form; In its internal composition, the parts by weight of each crude drug are: Radix Dipsaci 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Chuanxiong 10 parts, 10 parts, Flos Carthami, Arillus Longan 10 parts, Semen Cuscutae 10 parts, Radix Puerariae 10 parts, Herba Leonuri 10 parts, 10 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 10 parts; In its topical composition, the parts by weight of each crude drug are: Bombyx Batryticatus 20 parts, Rhizoma Typhonii 20 parts, the Radix Angelicae Dahuricae 20 parts, Borax 20 parts, 15 parts, Gypsum Fibrosum, Faeces Passeris 10 parts, 30 parts, Talcum, Borneolum Syntheticum 3 parts, Radix Arnebiae (Radix Lithospermi) 10 parts.

clinical data

1.1 physical data

This is organized 48 examples and is the court female outpatient patient.The oldest 48 years old, minimum 19 years old, average 27.5 years old, the course of disease was the longest 16 years, the shortest 6 months; Wherein family planning skin buries postoperative 11 examples, 7 examples after artificial abortion, point puerperium 24 example, Long-term Oral contraceptive 3 example, postoperative 3 examples of ectopic pregnancy side adnexectomy.

1.2 clinical manifestation

Face two cheek, forehead, bridge of the nose, mouth week, present filbert or light black near the eyes, differ in size, well-defined speckle, usually symmetrical in butterfly, put down in skin, NIP performance or squama; Most of patients has dysmenorrhea, menoxenia or chronic pelvic inflammatory disease concurrently.Get rid of caused by other chronic diseases such as hepatopathy, tuberculosis, diabetes, thyroid pathological changes.

2 Therapeutic Method

This organizes all cases all with Chinese medicine of the present invention for oral administration, and external Chinese medicine of the present invention is coated with outward, when the dosage form of the preparation of described internal composition is pill, when powder and capsule, each serving with 9-15g, and every day three times.Three parts are divided into after being mixed by decocting liquid after potion decocting twice every day during water decoction, at every turn a, every day three times.(preparation method of pill made pill with appropriate amount of starch and Mel after Chinese medicine for oral administration is pulverized 200 mesh sieve, the preparation method of powder made granule with appropriate amount of starch and edible essence after Chinese medicine for oral administration is pulverized 200 mesh sieve, directly incapsulated after Chinese medicine for oral administration being pulverized 200 mesh sieve during capsule.

The dosage form of external of the present invention is face film agent, and its preparation method is that external crude drug is developed into impalpable powder, and the Lac Bovis seu Bubali adding 1/2nd white vaseline amounts with white vaseline is in right amount mixed well, wipe after clean face sleep every night before once.January was 1 course for the treatment of, judged curative effect after treating 3 courses for the treatment of.Treatments period is stopped using other medicines and cosmetics, notes sun-proof, avoids pungent food, keep good mood, ensures enough to sleep.

3 criterions of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

With reference to " Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine promulgates for 1994.

Cure: yellowish-brown speckle all disappears, facial skin recovers normal;

Take a turn for the better: yellowish-brown plaque regression more than 30%, remainder color is obviously shallow

Invalid: yellowish-brown speckle without significant change, or disappears less than 30%.

3.2 therapeutic outcome

Cure 29 examples, take a turn for the better 14 examples, and invalid 5 examples, total effective rate is 89.58%.

Treatment time:

The fastest person of onset 18 ± 3 days, the slowest person 40 ± 5 days.

Case 1, field, female, 48 years old, born in wedlockly educating 4 tires, there is premenstrual abdominal pain over 16 years in artificial abortion 2 times, menstruation is suffered from abdominal pain after coming can spontaneous remission, and yellowish-brown patch appears in cycle 3-5 days, cycle 28-33 days cheeks and forehead portion, scope is 5cm*4cm size, and skin lesion boundary is clear, without desquamation, light when time is heavy, patient's nearly amounts in the period, 4 are many, and color secretly has clot, menstruation carrys out latter second day stomachache can spontaneous remission, menstrual period 5-7 days, cycle 35-46 days.

Fang Yong: Radix Dipsaci 30 parts, Radix Angelicae Sinensis 30 parts, Rhizoma Chuanxiong 15 parts, 15 parts, Flos Carthami, Arillus Longan 16 parts, Semen Cuscutae 16 parts, Radix Puerariae 15 parts, Herba Leonuri 15 parts, 15 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 15 parts.Encapsulated dose of clothes for oral administration.

Facial external application Chinese medicine face film agent is coordinated to be coated with outward, Fang Yong: Bombyx Batryticatus 10 parts, Rhizoma Typhonii 10 parts, the Radix Angelicae Dahuricae 10 parts, Borax 10 parts, 18 parts, Gypsum Fibrosum, Faeces Passeris 18 parts, 15 parts, Talcum, Borneolum Syntheticum 10 parts, Radix Arnebiae (Radix Lithospermi) 10 parts.

Case 2, Cao, female, 28 years old, because of after ectopic pregnancy row ride side attachment excision before 5 years, there is yellowish-brown patch in cheeks and forehead portion, scope is 6cm*8cm, skin lesion boundary is clear, and without desquamation, patient menstrual is few, color is dark, premenstrual abdominal pain, sharp ache, needing oral analgesic to menstruation to carry out latter second day stomachache can alleviate, menstrual period 2-4 days, cycle 25-32 days.

Fang Yong: Radix Dipsaci 35 parts, Radix Angelicae Sinensis 35 parts, Rhizoma Chuanxiong 20 parts, 20 parts, Flos Carthami, Arillus Longan 20 parts, Semen Cuscutae 20 parts, Radix Puerariae 20 parts, Herba Leonuri 20 parts, 20 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 12 parts.For oral administration make pill and take.

Facial external application Chinese medicine face film agent is coordinated to be coated with outward, Fang Yong: Bombyx Batryticatus 15 parts, Rhizoma Typhonii 15 parts, the Radix Angelicae Dahuricae 15 parts, Borax 15 parts, 30 parts, Gypsum Fibrosum, Faeces Passeris 9 parts, 22 parts, Talcum, Borneolum Syntheticum 7 parts, Radix Arnebiae (Radix Lithospermi) 15 parts.

Case 3, Xu certain, female, 19 years old, student, Reusability 4 kinds of different cosmetics before 6 months, there is yellowish-brown patch in cheeks and forehead portion, scope forehead is 4cm*9cm, cheeks portion all about 3cm*4cm skin lesion boundary is clear, bicker place is acne repeatedly, and patient menstrual is normal, without premenstrual abdominal pain, menstrual period 3-3 days, cycle 28-30 days.

Fang Yong: Radix Dipsaci 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Chuanxiong 10 parts, 10 parts, Flos Carthami, Arillus Longan 10 parts, Semen Cuscutae 10 parts, Radix Puerariae 10 parts, Herba Leonuri 10 parts, 10 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 10 parts.Decocting takes orally.

Facial external application Chinese medicine face film agent is coordinated to be coated with outward, Fang Yong: Bombyx Batryticatus 20 parts, Rhizoma Typhonii 20 parts, the Radix Angelicae Dahuricae 20 parts, Borax 20 parts, 15 parts, Gypsum Fibrosum, Faeces Passeris 10 parts, 30 parts, Talcum, Borneolum Syntheticum 3 parts, Radix Arnebiae (Radix Lithospermi) 10 parts.

Claims (2)

1. treat a Chinese medicine composition for chloasma, it is characterized in that: its by taking orally, external two groups of compositionss form; In its internal composition, the parts by weight of each crude drug are: Radix Dipsaci 20-35 parts, Radix Angelicae Sinensis 20 1 35 parts, Rhizoma Chuanxiong 10 1 20 parts, 10 1 20 parts, Flos Carthami, Arillus Longan 10 1 20 parts, Semen Cuscutae, 10 1 20 parts, Radix Puerariae 10 1 20 parts, Herba Leonuri 10 1 20 parts, 10 1 20 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 10 1 15 parts;

In its topical composition, the parts by weight of each crude drug are: Bombyx Batryticatus 10 1 20 parts, Rhizoma Typhonii 10 1 20 parts, the Radix Angelicae Dahuricae 10 1 20 parts, Borax 10 1 20 parts, 15 1 30 parts, Gypsum Fibrosum, Faeces Passeris 10 1 18 parts, 15 1 30 parts, Talcum, Borneolum Syntheticum 3 one 10 parts, Radix Arnebiae (Radix Lithospermi) 10 1 15 parts.

2. a kind of Chinese medicine composition for the treatment of chloasma according to claim 1, is characterized in that: its by taking orally, external two groups of compositionss form; In its internal composition, the parts by weight of each crude drug are: Radix Dipsaci 30 parts, Radix Angelicae Sinensis 30 parts, Rhizoma Chuanxiong 15 parts, 15 parts, Flos Carthami, Arillus Longan 16 parts, Semen Cuscutae 16 parts, Radix Puerariae 15 parts, Herba Leonuri 15 parts, 15 parts, Fructus Hordei Germinatus, Fructus Ligustri Lucidi 15 parts;

In its topical composition, the parts by weight of each crude drug are: Bombyx Batryticatus 10 parts, Rhizoma Typhonii 10 parts, the Radix Angelicae Dahuricae 10 parts, Borax 10 parts, 18 parts, Gypsum Fibrosum, Faeces Passeris 18 parts, 15 parts, Talcum, Borneolum Syntheticum 10 parts, Radix Arnebiae (Radix Lithospermi) 10 parts.