CN105055987A - Psoriasis treating traditional Chinese medicine preparation and preparation method thereof - Google Patents

Psoriasis treating traditional Chinese medicine preparation and preparation method thereof Download PDF

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Publication number
CN105055987A
CN105055987A CN201510305554.7A CN201510305554A CN105055987A CN 105055987 A CN105055987 A CN 105055987A CN 201510305554 A CN201510305554 A CN 201510305554A CN 105055987 A CN105055987 A CN 105055987A
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China
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parts
chinese medicine
traditional chinese
radix
psoriasis
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CN201510305554.7A
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Chinese (zh)
Inventor
王艳珍
吴丽艳
李晶莹
滕利荣
王静
孟凡欣
滕美玉
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Zhuhai College of Jilin University
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Zhuhai College of Jilin University
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Priority to CN201510305554.7A priority Critical patent/CN105055987A/en
Publication of CN105055987A publication Critical patent/CN105055987A/en
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Abstract

The present invention relates to a psoriasis treating traditional Chinese medicine and a preparation method thereof, wherein the psoriasis treating traditional Chinese medicine is prepared from the following bulk drugs by weight: garter snake, periostracum cicadae, sophora flavescens ait, tree peony bark, atractylodes lancea, cape jasmine, mulberry twig, cortex phellodendri, coix seed, nepeta cataria l, fallopia multiflora and licorice root. According to the present invention, the decoction, pills, dripping pills, granules, tablets, hard capsules, soft capsules, decocted extracts, syrups, oral solutions and beverages prepared according to the psoriasis treating traditional Chinese medicine have effects of heat clearing, blood cooling, wind-evil dispelling, itching stopping, blood stasis dissipating and dampness removing. The present invention further discloses the psoriasis treating traditional Chinese medicine product. The psoriasis treating traditional Chinese medicine of the present invention has characteristics of easily available raw materials, low prices, easy carrying, easy use, no toxic-side effect and the like, and provides a good treatment effect on psoriasis.

Description

One treats psoriatic Chinese medicine preparation and preparation method
Technical field
The open one of the present invention treats psoriatic Chinese medicine preparation, present invention also offers the preparation method of this Chinese medicine preparation, belongs to traditional Chinese medical science pharmaceutical technology sectors.
Background technology
Psoriasis, also known as psoriasis, is a kind of common chronic recurrent inflammatory dermatoses with characteristic skin lesion.Its course of disease is long, easy repeatedly, skin lesion is extensive, has a strong impact on the healthy of patient and quality of life.The psoriatic cause of disease and pathogenesis are not yet completely clear so far, and modern medicine thinks that this disease is the interactional disease of multifactorial inheritance of many factors such as inherited genetic factors, environmental factors, immune factor and infection.The traditional Chinese medical science think psoriatic morbidity and toxic heat in blood closely related, functional activity of QI being not smooth, strongly fragrant fire-transformation of a specified duration, internal injury caused by excess of seven emotions makes the nutrient blood and falling ill of heat volt, and the weight of heat in blood is directly related with the generation, development etc. of the state of an illness.Therefore, its determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is mainly carried out around clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, blood enriching and dryness moistening.
At present, western medicine psoriasis many application hormone, vitamin, immunosuppressant, immunomodulator etc., its short term effect is better, but toxic and side effects greatly can not life-time service, and easily recurs after drug withdrawal.Long and rich experience for differentiation of tcm treatment primary disease, determined curative effect and side effect is little, by extensive patients is accepted.
Summary of the invention
The invention provides one and treat psoriatic Chinese medicine preparation, there is little, the feature such as clinical effectiveness is obvious that has no side effect.
One of the present invention treats psoriatic Chinese medicine preparation, is made up of the raw material of following weight portion:
Zaocys 5 ~ 50 parts, Periostracum Cicadae 5 ~ 50 parts, Radix Sophorae Flavescentis 5 ~ 50 parts, Cortex Moutan 5 ~ 30 parts, Rhizoma Atractylodis 5 ~ 40 parts, Fructus Gardeniae 1 ~ 40 part, Ramulus Mori 1 ~ 30 part, Cortex Phellodendri 5 ~ 50 parts, Semen Coicis 5 ~ 50 parts, Herba Schizonepetae 5 ~ 50 parts, the Radix Polygoni Multiflori 5 ~ 50 parts, 1 ~ 20 part, Radix Glycyrrhizae.
of the present inventionone treats psoriatic Chinese medicine preparation, and preferred weight part of each raw material is:
Zaocys 20 parts, Periostracum Cicadae 20 parts, Radix Sophorae Flavescentis 20 parts, Cortex Moutan 15 parts, Rhizoma Atractylodis 20 parts, Fructus Gardeniae 15 parts, Ramulus Mori 10 parts, Cortex Phellodendri 20 parts, Semen Coicis 20 parts, Herba Schizonepetae 20 parts, the Radix Polygoni Multiflori 25 parts, 10 parts, Radix Glycyrrhizae.
of the present inventiontreat a preparation method for psoriatic capsule preparations, comprise the following steps:
Take Radix Sophorae Flavescentis, Cortex Moutan, Rhizoma Atractylodis, Fructus Gardeniae, Ramulus Mori, Cortex Phellodendri, Semen Coicis, Herba Schizonepetae, the Radix Polygoni Multiflori, Radix Glycyrrhizae in proportion, add 5 ~ 8 times amount soak by water 3 times, each 0.5 ~ 1.0 hour, decocting liquid filters, merge 3 filtrates, being concentrated into relative density is 1.12 (80 DEG C of heat are surveyed), obtains runny plaste; Zaocys, Periostracum Cicadae are ground into 80 order powder, add runny plaste, mixing, granulate (40 mesh sieve), dry 3 ~ 5 hours in 65 DEG C, obtain granule; Granule is incapsulated shell, obtains hard capsule.
Treatment psoriasis Chinese medicine preparation of the present invention Chinese medicine processing technique conveniently can make various pharmaceutical preparation.
[usage and dosage] is oral; 3 times/day; 5 ~ 10g/ time; Serious symptom can double to take.
[indication] psoriasis
Chinese medicine of the present invention is made up of by suitable proportioning Zaocys, Periostracum Cicadae, Radix Sophorae Flavescentis, Cortex Moutan, Rhizoma Atractylodis, Fructus Gardeniae, Ramulus Mori, Cortex Phellodendri, Semen Coicis, Herba Schizonepetae, the Radix Polygoni Multiflori, Radix Glycyrrhizae; Coordinate dispel loose ailment said due to cold or exposure, rash of Ramulus Mori antipruritic with Zaocys, Periostracum Cicadae, Radix Polygoni Multiflori, simultaneously by Rhizoma Atractylodis, Radix Sophorae Flavescentis, Cortex Phellodendri, Herba Schizonepetae, Semen Coicis heat clearing and damp drying, strengthen the spleen and stomach, be aided with Cortex Moutan, Fructus Gardeniae, Ramulus Mori clearing away heat and cooling blood, promoting blood circulation and detoxication, finally with the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription property of medicine.The present invention drafts in strict accordance with theory of Chinese medical science, crude drug according to the principle of " monarch, minister, help, make ", collaborative compatibility, jointly play dispelling wind for relieving itching, clearing away heat and cooling blood, the effect of blood stasis dispelling dehumidifying, the effect of mutual reinforcement between, the mutual-assistance can be reached, therefore to psoriasis, there is good therapeutical effect.
Choosing 100 routine psoriatics uses medicine of the present invention to treat, and its effective percentage is 85%; Obvious effective rate 90%; Inefficiency 10%.
Good effect of the present invention is: for psoriatic etiology and pathogenesis, and the guiding theory of its scheme of curing the disease should be main from clearing away heat and cooling blood, promoting blood circulation and detoxication; Selected medicine is natural medicinal plants, has dispelling wind for relieving itching, clearing away heat and cooling blood, blood stasis dispelling dehumidifying, blood enriching and dryness moistening, the effect of building up resistance, and medication is reasonable, and compatibility science, and determined curative effect, instant effect, nontoxic pair is little, higher through clinical verification cure rate.
Detailed description of the invention
In order to make those skilled in the art understand technical scheme of the present invention better, below by specific embodiment, the present invention is described in further detail, but protection scope of the present invention being not limited by the following examples.
embodiment 1
Get Zaocys 2kg, Periostracum Cicadae 2kg, Radix Sophorae Flavescentis 2kg, Cortex Moutan 1.5kg, Rhizoma Atractylodis 20kg, Fructus Gardeniae 1.5kg, Ramulus Mori 1kg, Cortex Phellodendri 2kg, Semen Coicis 2kg, Herba Schizonepetae 2kg, Radix Polygoni Multiflori 2.5kg, Radix Glycyrrhizae 1kg, Radix Sophorae Flavescentis, Cortex Moutan, Rhizoma Atractylodis, Fructus Gardeniae, Ramulus Mori, Cortex Phellodendri, Semen Coicis, Herba Schizonepetae, the Radix Polygoni Multiflori, Radix Glycyrrhizae are added 8 times amount soak by water 2 times, each 1 hour (keeping micro-to boil 1 hour), decocting liquid filters, merge 2 filtrates, be concentrated into relative density 1.15 (80 DEG C of heat are surveyed), obtain runny plaste; Zaocys, Periostracum Cicadae are ground into respectively powder (crossing 80 mesh sieves), add runny plaste, mixing, granulate (10 mesh sieve), dry 4 hours in 65 DEG C, obtain granule pack, often pack 2.5g.
embodiment 2
Get Zaocys 2kg, Periostracum Cicadae 2kg, Radix Sophorae Flavescentis 2kg, Cortex Moutan 1.5kg, Rhizoma Atractylodis 20kg, Fructus Gardeniae 1.5kg, Ramulus Mori 1kg, Cortex Phellodendri 2kg, Semen Coicis 2kg, Herba Schizonepetae 2kg, Radix Polygoni Multiflori 2.5kg, Radix Glycyrrhizae 1kg; Radix Sophorae Flavescentis, Cortex Moutan, Rhizoma Atractylodis, Fructus Gardeniae, Ramulus Mori, Cortex Phellodendri, Semen Coicis, Herba Schizonepetae, the Radix Polygoni Multiflori are added 5 times amount soak by water 3 times, each 0.5 hour (keeping micro-to boil 0.5 hour), decocting liquid filters, and merges 3 filtrates, being concentrated into relative density is 1.12 (80 DEG C of heat are surveyed), obtains runny plaste; Zaocys, Periostracum Cicadae are ground into powder (crossing 80 mesh sieves), add runny plaste, mixing, granulate (40 mesh sieve), dry 5 hours in 65 DEG C, obtain granule; Granule is incapsulated shell, and every capsule dress 0.5g, obtains hard capsule.
embodiment 3
Get Zaocys 20g, Periostracum Cicadae 20g, Radix Sophorae Flavescentis 15g, Cortex Moutan 15g, Rhizoma Atractylodis 20g, Fructus Gardeniae 10g, Ramulus Mori 10g, Cortex Phellodendri 15g, Semen Coicis 12g, Herba Schizonepetae 20g, Radix Polygoni Multiflori 30g, Radix Glycyrrhizae 8g, add suitable quantity of water and soak half an hour, little fire boils half an hour, filters, obtains Chinese herbs decoction.
embodiment 4
Get Zaocys 800g, Periostracum Cicadae 800g, Radix Sophorae Flavescentis 800g, Cortex Moutan 600g, Rhizoma Atractylodis 800g, Fructus Gardeniae 600g, Ramulus Mori 40g, Cortex Phellodendri 80g, Semen Coicis 80g, Herba Schizonepetae 80g, Radix Polygoni Multiflori 1kg, Radix Glycyrrhizae 80g.Zaocys, Periostracum Cicadae are ground into powder (crossing 80 mesh sieves), for subsequent use; Radix Sophorae Flavescentis, Cortex Moutan, Rhizoma Atractylodis, Fructus Gardeniae, Ramulus Mori, Cortex Phellodendri, Semen Coicis, Herba Schizonepetae, the Radix Polygoni Multiflori, Radix Glycyrrhizae added for 8 times amount water soaking half an hour, heated and boiled 1 hour, filter, it is 1.10 (80 DEG C of heat are surveyed) that filtrate is concentrated into relative density, add a certain proportion of medicinal dextrin, mixing, dry 5 hours in 70 DEG C, pulverize, then to add Zaocys powder, Periostracum Cicadae powder, a certain proportion of soluble starch and concentration be 65% simple syrup, mixing, granulate (40 mesh sieve), gained granule dries 5 hours in 70 DEG C, is pressed into plain sheet (every sheet weighs 0.4 gram), sugar coating, obtains tablet.
embodiment 5
Get Zaocys 60g, Periostracum Cicadae 60g, Radix Sophorae Flavescentis 40g, Cortex Moutan 50g, Rhizoma Atractylodis 40g, Fructus Gardeniae 40g, Ramulus Mori 30g, Cortex Phellodendri 30g, Semen Coicis 30g, Herba Schizonepetae 40g, Radix Polygoni Multiflori 40g, Radix Glycyrrhizae 10g be ground into powder (crossing 80 mesh sieves) respectively, mixing, every 100 grams of powder refined honeys 75 grams add appropriate water pill, dry 6 hours in 70 DEG C, obtain water-honeyed pill.
embodiment 6
Get Zaocys 100g, Periostracum Cicadae 100g, Radix Sophorae Flavescentis 100g, Cortex Moutan 70g, Rhizoma Atractylodis 50g, Fructus Gardeniae 10g, Ramulus Mori 15g, Cortex Phellodendri 50g, Semen Coicis 50g, Herba Schizonepetae 60g, Radix Polygoni Multiflori 50g, Radix Glycyrrhizae 20g, added for 8 times amount water soaking half an hour, heated and boiled 1 hour, filter, filtering residue added for 6 times amount water boil half an hour again, filtered, merge secondary filtrate, be condensed into runny plaste, it is appropriate to add certain density simple syrup, stir evenly, cooling, adds water to 2000 milliliters, stir evenly, leave standstill, filter, embedding, obtains oral liquid.
the therapeutic effect of medicine of the present invention is shown further by following model case:
case 1
Wu, female, 32 years old, there is little erythema in their early stage skin, and in some drop-wise, constantly become large, some becomes coin shape.PD is relatively rapider, and erythra color is scarlet, is distributed in extremity and back, comparatively disperses, and with pruritus, usually feels restlessness and thirst, is hard and dry, oliguria with yellow urine.Get embodiment 1 in the present invention and prepare medicine, after taking 1 month, erythra obviously reduces, and scratchiness is without strong before.Disappear, after continuing to take 2 months, Schultz-Charlton.
case 2
Zhang, female, 15 years old, symptom was that focus appears in skin, and back has red papules, Semen phaseoli radiati large, is covered with the argenteous skin as scale above, squama is scraped apart from the shinny thin film of one deck, scratch thin film there will be little petechia with have gentle hands.Take the hard capsule of preparation in embodiment 2, every day 3 times, each 4, after taking 2 months, symptom is obviously improved, and squama comes off completely, and medication is after 2 months again, and whole skin recovers normal.Withdraw and have no recurrence.
case 3
Grandson, man, 45 years old, ill 1 year, initial stage site of disease had the flat pimple of polygon of assembling tendency, and because of the hard to bear frequent scratching of pruritus, pimple spreads, and merges in flakes, and the local skin lesion that continues thickens texture to be deepened, and dry tack free, has a little squama, clear border.Patient once took Chinese medicine and Western medicine, and curative effect is very micro-.Patient is the hormones ointment because of wiping again, causes skin lesion area to increase.Take the tablet of preparation in embodiment 4, every day 3 times, each 4, after taking 1 month, skin lesion reduces, and takes after four months and recovers normal.
Above to invention has been detailed introduction, applying specific case and setting forth principle of the present invention and embodiment in literary composition, the explanation of above embodiment just understands method of the present invention and core concept thereof for helping.It should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention, can also carry out some improvement and modification to the present invention, these improve and modify and also fall in the protection domain of the claims in the present invention.

Claims (4)

1. treat a psoriatic Chinese medicine, be made up of the raw material of following weight portion:
Zaocys 5 ~ 50 parts, Periostracum Cicadae 5 ~ 50 parts, Radix Sophorae Flavescentis 5 ~ 50 parts, Cortex Moutan 5 ~ 30 parts, Rhizoma Atractylodis 5 ~ 40 parts, Fructus Gardeniae 1 ~ 40 part, Ramulus Mori 1 ~ 30 part, Cortex Phellodendri 5 ~ 50 parts, Semen Coicis 5 ~ 50 parts, Herba Schizonepetae 5 ~ 50 parts, the Radix Polygoni Multiflori 5 ~ 50 parts, 1 ~ 20 part, Radix Glycyrrhizae.
2. the psoriatic Chinese medicine for the treatment of according to claim 1, preferred prescription is:
Zaocys 20 parts, Periostracum Cicadae 20 parts, Radix Sophorae Flavescentis 20 parts, Cortex Moutan 15 parts, Rhizoma Atractylodis 20 parts, Fructus Gardeniae 15 parts, Ramulus Mori 10 parts, Cortex Phellodendri 20 parts, Semen Coicis 20 parts, Herba Schizonepetae 20 parts, the Radix Polygoni Multiflori 25 parts, 10 parts, Radix Glycyrrhizae.
3. the psoriatic Chinese medicine for the treatment of according to claim 1,2 Chinese medicine processing technique conveniently can make various pharmaceutical preparation.
4. treat a preparation method for psoriatic capsule preparations, comprise the following steps:
Take Radix Sophorae Flavescentis, Cortex Moutan, Rhizoma Atractylodis, Fructus Gardeniae, Ramulus Mori, Cortex Phellodendri, Semen Coicis, Herba Schizonepetae, the Radix Polygoni Multiflori, Radix Glycyrrhizae in proportion, add 5 ~ 8 times amount soak by water 3 times, each 0.5 ~ 1.0 hour, decocting liquid filters, merge 3 filtrates, being concentrated into relative density is 1.12 (80 DEG C of heat are surveyed), obtains runny plaste; Zaocys, Periostracum Cicadae are ground into 80 order powder, add runny plaste, mixing, granulate (40 mesh sieve), dry 3 ~ 5 hours in 65 DEG C, obtain granule; Granule is incapsulated shell, and every capsule dress 0.5g, obtains hard capsule.
CN201510305554.7A 2015-06-08 2015-06-08 Psoriasis treating traditional Chinese medicine preparation and preparation method thereof Pending CN105055987A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111743981A (en) * 2020-08-06 2020-10-09 辽宁宝一堂科技发展有限公司 Preparation method of cleaning liquid medicine for treating psoriasis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57150620A (en) * 1981-03-13 1982-09-17 Akira Izuno Specific remedy for athlete's foot and psoriasis
CN103239656A (en) * 2013-05-06 2013-08-14 刘芳 Traditional Chinese medicine for treating psoriasis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57150620A (en) * 1981-03-13 1982-09-17 Akira Izuno Specific remedy for athlete's foot and psoriasis
CN103239656A (en) * 2013-05-06 2013-08-14 刘芳 Traditional Chinese medicine for treating psoriasis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
丁艳玲等: "乌蛇搜风饮治疗银屑病68例", 《陕西中医》 *
叶景华: "《简明中医临床诊治手册》", 31 December 2006 *
湖南牛皮癣专科医院: "长沙牛皮癣医院哪家最好", 《HTTP://BLOG.SINA.COM.CN/S/BLOG_BB25EBC80101CNKW.HTML》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111743981A (en) * 2020-08-06 2020-10-09 辽宁宝一堂科技发展有限公司 Preparation method of cleaning liquid medicine for treating psoriasis

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Application publication date: 20151118