CN1050519C - Chinese medicine granule for acne - Google Patents

Chinese medicine granule for acne Download PDF

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Publication number
CN1050519C
CN1050519C CN95119506A CN95119506A CN1050519C CN 1050519 C CN1050519 C CN 1050519C CN 95119506 A CN95119506 A CN 95119506A CN 95119506 A CN95119506 A CN 95119506A CN 1050519 C CN1050519 C CN 1050519C
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radix
grams
rhizoma
hours
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CN95119506A
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CN1151879A (en
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祝继兴
祝宇
孙立香
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Abstract

The present invention discloses an oral medicine used for treating acne, which is prepared from amur corktree bark, baical skullcap root, cape jasmine fruit, plaster stone, rhubarb, honeysuckle flower, purple gromwell root, tree peony bark, radix rehmanniae, lalang grass rhizome, oriental wormwood, glabrous greenbrier rhizome, dragon bone, oyster shell and licorice root.

Description

The Chinese medicine electuary of treatment acne
The present invention is a kind of Chinese patent medicine that is used for the treatment of a skin ulcer, and it is the electuary made from effective components of Chinese medicinal.Belong to field of pharmaceutical preparations.
Acne is sent out in the men and women adolescence well, and the course of disease is longer, and is bigger to the influence attractive in appearance of face.When just sending out is pinhead-sized pimple, is called during the black of top " blackhead ".Can send out after the infection and be pustule, even swelling.Existing treatment Cuo bleb medicine is many with external, as the CN1087821A patent disclosure a kind of medicament and preparation method of removing acne.Examination is put in this medicament external on the skin, and the effect of certain treatment seat skin ulcer is arranged.The CN1080182A patent disclosure a kind of acne (acne) treatments breast and manufacture method thereof.This treatment breast belongs to a kind of cosmeceutical of external, and acne is also had certain therapeutic effect.Though above-mentioned medicament or cosmetics are effectively most, curative effect is not remarkable.Contain the acne treatment medicine commonly used of Chinese herbal medicine, belong to water decoction or tincture more, color and luster is volatile deeply, is put on not attractive in appearance on the face.
The purpose of this invention is to provide a kind of endo-medicine for the treatment of acne.
The etiology and pathogenesis of acne, multistage lung meridian is hot and suffocating, or the intestines and stomach is damp and hot or be subjected to wind heat outward, so that evil strongly fragrant lung stomach, damp and hot fumigation, grandson's network is not smooth, and heat in blood stagnates in facial and form.Said as the Tang Dynasty Wang Bing " element is asked note ": " heat is surplus, strongly fragrant in flesh side in stroking, acne very, and little is miliaria." the former rule of treatment to acne, how damp and hot with removing summer-heat, the removing heat from blood and promoting blood circulation method.According to above-mentioned theory.Monarch drug is selected the Cortex Phellodendri bitter cold for use in the medicine of the present invention, and abnormal smells from the patient is all thick, and property master sedimentation can be hot and suffocating clearly, rushes down turbid damp, and YIN nourishing is sensible, leads the descending road of damp and hot drainage.The ministerial drug Radix Scutellariae is longer than the heat clearing away lung-heat, and Fructus Gardeniae is longer than three warmers heat clearly, and Gypsum Fibrosum is longer than clearing away stomach-heat, and the bowel relieving gastric heat is longer than by Radix Et Rhizoma Rhei, Flos Lonicerae is longer than clearing heat in QI system, five compatibilities, and the efficacy of a drug is concentrated and is let out the lung stomach clearly, not only can vegetables lead damp and hotly, and heat-clearing and toxic substances removing also has the energy of dissipation sore swollen toxin.Be aided with Radix Arnebiae (Radix Lithospermi) removing heat from blood removing toxic substances again, Cortex Moutan blood circulation promoting and blood stasis dispelling, Radix Rehmanniae YIN nourishing removing heat from blood, Rhizoma Imperatae dampness removing clots absorbing, four compatibilities, current blood vessels are dispeled the stasis of blood and are stagnated, among beauty treatment, use it, not only help transferring smooth breath, dredging the meridian is led the turbid heresy of the damp and hot stasis of blood off, simultaneously more can bring into play smoothing skin, make the effect of the bright and clean exquisiteness of complexion.Assistant can strengthen heat-clearing and toxic substances removing with Herba Artemisiae Scopariae, Rhizoma Smilacis Glabrae, the merit that the dissipation skin infection is swollen.Os Draconis, Concha Ostreae nourishing YIN for attracting YANG can put out the high inflammation of asthenic fire, thereby the double usefulness of employing of specimen is arranged, and then exopathogen removes in this way, and endogenous fire is clear.45 usefulness, assistant helps monarch-minister drug, and long-pending lung stomach is accumulate in damp and hot pent-up such as, and acne and seborrheic dermatitis that heat in blood stagnates and occurs in face, and darkish face and eyes also should be used.Make with the Radix Glycyrrhizae heat-clearing and toxic substances removing, and with transfer the property of medicine, make the harmless stomach of cold and cool medicine hinder the suspicion of food.All medicines are comprehensive, play the elimination acne altogether, and skin care is pleased the effect of face.
Therefore, medicine of the present invention is made up of following component:
Cortex Phellodendri 20-30 weight portion Radix Scutellariae 10-20 weight portion
Fructus Gardeniae 10-20 weight portion Gypsum Fibrosum 20-30 weight portion
Radix Et Rhizoma Rhei 5-15 weight portion Flos Lonicerae 10-20 weight portion
Radix Arnebiae (Radix Lithospermi) 5-15 weight portion Cortex Moutan 5-15 weight portion
Radix Rehmanniae 5-15 weight portion Rhizoma Imperatae 10-20 weight portion
Herba Artemisiae Scopariae 10-20 weight portion Rhizoma Smilacis Glabrae 5-15 weight portion
Os Draconis 5-15 weight portion Concha Ostreae 5-15 weight portion
Radix Glycyrrhizae 5-15 weight portion
The optimum weight proportioning of above-mentioned each Chinese medicine component is as follows:
Cortex Phellodendri 25 weight portion Radix Scutellariaes 15 weight portions
Fructus Gardeniae 15 weight portion Gypsum Fibrosum 25 weight portions
Radix Et Rhizoma Rhei 10 weight portion Flos Loniceraes 15 weight portions
Radix Arnebiae (Radix Lithospermi) 10 weight portion Cortex Moutans 10 weight portions
The Radix Rehmanniae 10 weight portion Rhizoma Imperataes 15 weight portions
Herba Artemisiae Scopariae 15 weight portion Rhizoma Smilacis Glabraes 10 weight portions
Os Draconis 10 weight portion Concha Ostreaes 10 weight portions
Radix Glycyrrhizae 10 weight portions
Above-mentioned endo-medicine of the present invention can be according to the preparation process preparation commonly used oral medicine of prescription with routine, as tablet, electuary, pill, oral liquid, capsule etc.
The preparation method of endo-medicine electuary of the present invention is: get Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Arnebiae (Radix Lithospermi), Cortex Moutan earlier, with 80% alcohol reflux twice, add 8 times of amount ethanol for the first time, extracted 2 hours, add 6 times of amount ethanol for the second time, carry 2 hours.Filter, merge alcohol extract twice, decompression recycling ethanol, and be concentrated into relative density and be 1.18-1.20 (80 ℃), standby; Gypsum Fibrosum, Os Draconis, Concha Ostreae add 8 times of amounts of water in addition, decocted 1 hour, again the Cortex Phellodendri after Fructus Gardeniae, Radix Scutellariae, Flos Lonicerae, the Radix Rehmanniae, Rhizoma Imperatae, Herba Artemisiae Scopariae, Rhizoma Smilacis Glabrae, Radix Glycyrrhizae and the alcohol extraction, Radix Et Rhizoma Rhei, Radix Arnebiae (Radix Lithospermi), Cortex Moutan medicinal residues are added, in multi-function extractor, adding watertight decocts three times, for the first time add 8 times of amounts of water, decocted 2 hours; For the second time add 6 times of amounts of water, decocted 2 hours, add 6 times of amounts of water for the third time, decocted 1 hour, and collected volatile oil simultaneously, merge three times decocting liquid, being concentrated into concentration is 1.28-1.3 (80 ℃), merge with pure extractum,, pulverize in 60 ℃ of dryings, add the cane sugar powder that doubling dose is dry in advance, pulverize and cross the 80-100 mesh sieve, mixing adds an amount of 73% ethanol and makes soft material, with the powder process of 10-12 mesh sieve.In 60 ℃ of dryings, put coldly, spray into the volatile oil extracting solution, mixing, airtight 2 hours, promptly.
In the process of above-mentioned preparation electuary, total crude drug amount 20500 grams of writing out a prescription go out granule 1000 grams.Every restraint agent contains crude drug amount 2.05 grams.Every bag 10 gram dress is equivalent to crude drug in whole 20.5 grams.Using method is 1 bag of each clothes, every day three times.
Medicine instant of the present invention has tangible bacteriostasis and antiinflammatory action, uses closure furuncle and phyma, the swelling area of mice to dwindle pain relief in the furuncle and phyma test of animal.Can improve the humoral immune function of mice significantly through mouse stomach administration one week proof medicine of the present invention.In test for celluar immunity, this electuary can improve the phagocytic activity of Turnover of Mouse Peritoneal Macrophages significantly.
Embodiment
Prescription:
Cortex Phellodendri 25 gram Radix Scutellariaes 15 gram Fructus Gardeniaes 15 grams
Gypsum Fibrosum 25 gram Radix Et Rhizoma Rhei 10 gram Flos Loniceraes 15 grams
The Radix Arnebiae (Radix Lithospermi) 10 gram Cortex Moutans 10 gram Radix Rehmanniae 10 grams
Rhizoma Imperatae 15 gram Herba Artemisiae Scopariaes 15 gram Rhizoma Smilacis Glabraes 10 grams
Os Draconis 10 gram Concha Ostreaes 10 gram Radix Glycyrrhizaes 10 grams
Method for making:
More than 15, get Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Arnebiae (Radix Lithospermi), Cortex Moutan with twice of 80% alcohol reflux, for the first time add 8 times of amounts of ethanol, extracted 2 hours, add 6 times of amounts of ethanol for the second time, extract 2 little, filter, merge alcohol extract twice, decompression recycling ethanol, and be concentrated into relative density and be 1.18-1.20 (80 ℃), standby; Gypsum Fibrosum in addition, Os Draconis, Concha Ostreae adds 8 times of amounts of water, decocted 1 hour, again with Fructus Gardeniae, Radix Scutellariae, Flos Lonicerae, the Radix Rehmanniae, Rhizoma Imperatae, Herba Artemisiae Scopariae, Rhizoma Smilacis Glabrae, medicinal residues after Radix Glycyrrhizae and the alcohol extraction add, and in multi-function extractor, add watertight and boil three times, add for the first time 8 times in water, decocted 2 hours, and added 6 times in water for the second time, decocted 2 hours, add 6 times of amounts of water for the third time, decocted 1 hour, and collected volatile oil simultaneously, merge three times decocting liquid, being concentrated into relative density is 1.28-1.3 (80 ℃), merge with pure extractum,, pulverize in 60 ℃ of dryings, it is dry in advance to add doubling dose, pulverize and cross the cane sugar powder of 80-100 mesh sieve, mixing adds an amount of 73% ethanol and makes soft material, granulates with the 10-12 mesh sieve, in 60 ℃ of dryings, put cold.Spray into the volatile oil extracting solution, mixing, airtight 2 hours, promptly.

Claims (4)

1. oral medicine for the treatment of acne is characterized in that it is made by following proportion raw material by weight:
Cortex Phellodendri 20-30 Radix Scutellariae 10-20 Fructus Gardeniae 10-20
Gypsum Fibrosum 20-30 Radix Et Rhizoma Rhei 5-15 Flos Lonicerae 10-20
Radix Arnebiae (Radix Lithospermi) 5-15 Cortex Moutan 5-15 Radix Rehmanniae 5-15
Rhizoma Imperatae 10-20 Herba Artemisiae Scopariae 10-20 Rhizoma Smilacis Glabrae 5-15
Os Draconis 5-1 5 Concha Ostreae 5-15 Radix Glycyrrhizae 5-15.
2. endo-medicine according to claim 1 is characterized in that used proportion raw material by weight is:
Cortex Phellodendri 25 Radix Scutellariaes 15 Fructus Gardeniaes 15
Gypsum Fibrosum 25 Radix Et Rhizoma Rhei 10 Flos Loniceraes 15
Radix Arnebiae (Radix Lithospermi) 10 Cortex Moutans 10 Radix Rehmanniae 10
Rhizoma Imperatae 15 Herba Artemisiae Scopariaes 15 Rhizoma Smilacis Glabraes 10
Os Draconis 10 Concha Ostreaes 10 Radix Glycyrrhizaes 10.
3. medicine according to claim 1 and 2, wherein said endo-medicine is an electuary.
4. preparation method for the treatment of the electuary of acne, it is characterized in that getting Cortex Phellodendri 2500 grams, Radix Et Rhizoma Rhei 1000 grams, Radix Arnebiae (Radix Lithospermi) 1000 grams, Cortex Moutan 1000 gram is with twice of 80% alcohol reflux, alcohol adding amount is respectively 8 times, 6 times, reflux extracting time was respectively 2 hours, 2 hours, filter, merge alcohol extract twice, decompression recycling ethanol, and the relative density that is concentrated into 80 ℃ is 1.18-1.20, standby, in addition with Gypsum Fibrosum 2500 grams, Os Draconis 1000 grams, Concha Ostreae 1000 grams, add 8 times of amounts of water, decocted 1 hour, again with Fructus Gardeniae 1500 grams, Radix Scutellariae 1500 grams, Flos Lonicerae 1500 grams, the Radix Rehmanniae 1000 grams, Rhizoma Imperatae 1500 grams, Herba Artemisiae Scopariae 1500 grams, Rhizoma Smilacis Glabrae 1000 grams, medicinal residues after Radix Glycyrrhizae 1000 grams and the alcohol extraction add, in multi-function extractor, adding watertight decocts three times, amount of water is respectively 8 times, 6 times, 6 times, decocting time was respectively 2 hours, 2 hours, 1 hour, collect volatile oil simultaneously, merge three times decocting liquid, the relative density that is concentrated into 80 ℃ is 1.28-1.3, merges with pure extractum, in 60 ℃ of dryings, pulverize, it is dry in advance to add doubling dose, pulverize and cross the cane sugar powder of 80-100 mesh sieve, mixing, add an amount of 73% ethanol and make soft material, granulate with the 10-12 mesh sieve,, put cold in 60 ℃ of dryings, spray into the volatile oil extracting solution, mixing, airtight 2 hours, promptly.
CN95119506A 1995-12-14 1995-12-14 Chinese medicine granule for acne Expired - Fee Related CN1050519C (en)

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Application Number Priority Date Filing Date Title
CN95119506A CN1050519C (en) 1995-12-14 1995-12-14 Chinese medicine granule for acne

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CN1050519C true CN1050519C (en) 2000-03-22

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100404047C (en) * 2005-07-22 2008-07-23 张友生 Medicinal composition for treating acne and eczema and its preparing method

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1092063C (en) * 1999-06-11 2002-10-09 韩英祥 Recipe of medicine for acne and plane warts
CN100339097C (en) * 2005-06-15 2007-09-26 李德森 Compound ointment for treating acne
CN100386106C (en) * 2006-06-23 2008-05-07 段阳泉 Medicine for treating acne and its preparation
CN100434107C (en) * 2006-07-03 2008-11-19 丛吉兵 Acne clearing decoction
CN105327206A (en) * 2015-12-03 2016-02-17 威海紫光金奥力生物技术有限公司 Traditional Chinese medicine health-care food capable of effectively removing acnes

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1071841A (en) * 1991-10-31 1993-05-12 张明 The preparation of Chinese medicine compound Flos Sophorae and production technology
CN1098005A (en) * 1994-03-29 1995-02-01 李长春 The medicine and the method for treatment acne

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1071841A (en) * 1991-10-31 1993-05-12 张明 The preparation of Chinese medicine compound Flos Sophorae and production technology
CN1098005A (en) * 1994-03-29 1995-02-01 李长春 The medicine and the method for treatment acne

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100404047C (en) * 2005-07-22 2008-07-23 张友生 Medicinal composition for treating acne and eczema and its preparing method

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