CN105031705A - Contact lens disinfecting and moisturizing medicinal solution - Google Patents

Contact lens disinfecting and moisturizing medicinal solution Download PDF

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Publication number
CN105031705A
CN105031705A CN201510359285.2A CN201510359285A CN105031705A CN 105031705 A CN105031705 A CN 105031705A CN 201510359285 A CN201510359285 A CN 201510359285A CN 105031705 A CN105031705 A CN 105031705A
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China
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parts
contact lens
agent
liquid medicine
sodium
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Pending
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CN201510359285.2A
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Chinese (zh)
Inventor
杨海霞
黄红林
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Individual
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Individual
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Priority to CN201510359285.2A priority Critical patent/CN105031705A/en
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Abstract

The invention discloses a contact lens disinfecting and moisturizing medicinal solution which includes the following components: 5-12 parts of trisodium citrate dihydrate, 15-25 parts of boric acid, 15-25 parts of sorbitol, 2-5 parts of edetate disodium, 3-6 parts of sodium chloride, 11-15 parts of aminomethyl propanol, 2-4 parts of sodium borate, 4-8 parts of polyoxyethylene, 5-10 parts of polyquaternium, 5-8 parts of myristyl dimethylamine, 15-30 parts of a humectant, 5-15 parts of a protein removing agent, 5-10 parts of a buffer, 5-10 parts of an osmotic pressure adjusting agent and 2-5 parts of a chelating agent. The contact lens disinfecting and moisturizing medicinal solution provided by the invention has the advantages that the solution has a strong moisturizing effect, can remove protein accumulation as well as grease and dirt, has a disinfection function, and can keep the lens clean, enhance the surface wettability of the lens, and maintain comfortable sensation during wearing.

Description

A kind of contact lens disinfection moisturizing liquid medicine
[technical field]
The present invention relates to the technical field of contact lens disinfection moisturizing liquid medicine.
[background technology]
Contact lens liquid medicine is that contact lens race all uses every day, and the deposit of lens surface and pathogen must first be removed with contact lens liquid medicine, and ensuing like this sterilization preservation could effectively be carried out.Because clean incomplete lens surface meeting relict sediment, when directly sterilizing, sterilization composition only can be combined with deposit, and cannot be combined with pathogen, sterilization composition just can not play bactericidal action, on the other hand, the general moistening effect of contact lens liquid medicine on market is undesirable, easily causes the dry and astringent fatigue of glasses.
[summary of the invention]
Object of the present invention solves the problems of the prior art exactly, a kind of contact lens disinfection moisturizing liquid medicine is proposed, there is high moistening effect, remove protein accumulation, disinfection, effectively suppresses harmful microorganism, remove oils and fats and dust and dirt, keep eyeglass to clean, strengthen lens surface wettability simultaneously, keep the advantages such as comfortable wearing sense.
For achieving the above object, the present invention proposes a kind of contact lens disinfection moisturizing liquid medicine, comprise following component and the ratio of each component is: two citric acid monohydrate sodium: 5 parts ~ 12 parts, boric acid: 15 parts ~ 25 parts, sorbitol: 15 parts ~ 25 parts, disodium edetate: 2 parts ~ 5 parts, sodium chloride: 3 parts ~ 6 parts, aminomethyl propanol: 11 parts ~ 15 parts, sodium borate: 2 parts ~ 4 parts, polybutylene: 4 parts ~ 8 parts, polyquaternary ammonium salt: 5 parts ~ 10 parts, myristoyl diemethylamine: 5 parts ~ 8 parts, wetting agent: 15 parts ~ 30 parts, isolating protein agent: 5 parts ~ 15 parts, buffer agent: 5 parts ~ 10 parts, osmotic pressure regulator: 5 parts ~ 10 parts, chelating agen: 2 parts ~ 5 parts.
As preferably, described wetting agent is the mixture of polyoxyethylene, polyoxypropylene, mixed proportion polyoxyethylene: polyoxypropylene is 3:7.
As preferably, described isolating protein agent adopt in hydrogen peroxide, normal saline, expoxy propane, oxirane any one.
As preferably, described buffer agent adopt in hydroxypropyl methylcellulose, Tai Luoshabai any one.
As preferably, described osmotic pressure regulator adopt in lecithin phosphorus phthalate buffer, glucose, sodium sulfate any one.
As preferably, described chelating agen adopts phosphate, amino carboxylic acid, 1,3-diketone, in hydroxy carboxylic acid, polyamines any one.
As preferably, comprise following component and the ratio of each component is: comprise following component and the ratio of each component is: two citric acid monohydrate sodium: 6 parts, boric acid: 16 parts, sorbitol: 15 parts, disodium edetate: 3 parts, sodium chloride: 4 parts, aminomethyl propanol: 12 parts, sodium borate: 2 parts, polybutylene: 6 parts, polyquaternary ammonium salt: 6 parts, myristoyl diemethylamine: 8 parts, wetting agent: 18 parts, isolating protein agent: 5 parts, buffer agent: 7 parts, osmotic pressure regulator: 7 parts, chelating agen: 4 parts.
As preferably, comprise following component and the ratio of each component is: two citric acid monohydrate sodium: 12 parts, boric acid: 25 parts, sorbitol: 25 parts, disodium edetate: 5 parts, sodium chloride: 6 parts, aminomethyl propanol: 15 parts, sodium borate: 4 parts, polybutylene: 8 parts, polyquaternary ammonium salt: 510 parts, myristoyl diemethylamine: 8 parts, wetting agent: 30 parts, isolating protein agent: 15 parts, buffer agent: 10 parts, osmotic pressure regulator: 10 parts, chelating agen: 5 parts.
Beneficial effect of the present invention: the present invention adopts wetting agent to be polyoxyethylene, bring up the mixture of propylene, its mixed proportion is polyoxyethylene: polyoxypropylene is 3:7, effectively can increase the retentiveness of eyeglass, strengthen the wettability on its surface, keep the comfort level worn, described isolating protein agent adopts hydrogen peroxide, normal saline, expoxy propane, any one in oxirane, can effective decomposing protein, sterilization scale removal, reduce harmful microbe to grow, buffer agent adopts hydroxypropyl methylcellulose, any one in Tai Luoshabai, effectively can control acid-base value, increase water-setting molecule, contact lens liquid medicine gentleness is not stimulated, improve comfortable wearing degree, described osmotic pressure regulator adopts lecithin phosphorus phthalate buffer, glucose, any one in sodium sulfate, regulate the osmotic pressure being applicable to eye table environment, the liquid medicine of isosmoticity can maintain the parameter of eyeglass within normal range, chelating agen adopts phosphate, amino carboxylic acid, 1, 3-diketone, hydroxy carboxylic acid, in polyamines any one, adding of chelating agen makes breaks down proteins accelerate, catalytic action strengthens, make the protein dispersibility decomposed, there is the collaborative cleaning action of lens surface activating agent.
[detailed description of the invention]
A kind of contact lens disinfection moisturizing of the present invention liquid medicine, comprise following component and the ratio of each component is: two citric acid monohydrate sodium: 5 parts ~ 12 parts, boric acid: 15 parts ~ 25 parts, sorbitol: 15 parts ~ 25 parts, disodium edetate: 2 parts ~ 5 parts, sodium chloride: 3 parts ~ 6 parts, aminomethyl propanol: 11 parts ~ 15 parts, sodium borate: 2 parts ~ 4 parts, polybutylene: 4 parts ~ 8 parts, polyquaternary ammonium salt: 5 parts ~ 10 parts, myristoyl diemethylamine: 5 parts ~ 8 parts, wetting agent: 15 parts ~ 30 parts, isolating protein agent: 5 parts ~ 15 parts, buffer agent: 5 parts ~ 10 parts, osmotic pressure regulator: 5 parts ~ 10 parts, chelating agen: 2 parts ~ 5 parts.
Described wetting agent is the mixture of polyoxyethylene, polyoxypropylene, mixed proportion polyoxyethylene: polyoxypropylene is 3:7, described isolating protein agent adopt in hydrogen peroxide, normal saline, expoxy propane, oxirane any one, described buffer agent adopt in hydroxypropyl methylcellulose, Tai Luoshabai any one, described osmotic pressure regulator adopt in lecithin phosphorus phthalate buffer, glucose, sodium sulfate any one, described chelating agen adopts phosphate, amino carboxylic acid, 1,3-diketone, in hydroxy carboxylic acid, polyamines any one.
Contact lens liquid medicine is mainly by citric acid monohydrate sodium, boric acid, sorbitol, disodium edetate, sodium chloride, aminomethyl propanol, sodium borate, polybutylene, polyquaternary ammonium salt, the degrade proteins of each component of myristoyl diemethylamine isoequilibrium, the material of moisturizing is formed, surface wettability degree can be strengthened on the one hand, strengthen moisturizing comfort, eye is releived drying, on the other hand can disinfection, the useless albumen that effective removal cornea metabolism produces, breaks down proteins is disperseed, adding of osmotic pressure regulator and buffer agent, more hydro-cushion can be kept, remove uncomfortable effect, remove foreign body sensation, it is the preferably selection of sensitive group, chelating agen to add the storage after making lens cleaning safer, the protein of decomposition can not be regrouped and produce precipitation, affect bactericidal effect.
Embodiment one:
A kind of contact lens disinfection moisturizing liquid medicine, comprise following component and the ratio of each component is: two citric acid monohydrate sodium: 6 parts, boric acid: 16 parts, sorbitol: 15 parts, disodium edetate: 3 parts, sodium chloride: 4 parts, aminomethyl propanol: 12 parts, sodium borate: 2 parts, polybutylene: 6 parts, polyquaternary ammonium salt: 6 parts, myristoyl diemethylamine: 8 parts, wetting agent: 18 parts, isolating protein agent: 5 parts, buffer agent: 7 parts, osmotic pressure regulator: 7 parts, chelating agen: 4 parts, described wetting agent is polyoxyethylene, the mixture of polyoxypropylene, mixed proportion polyoxyethylene: polyoxypropylene is 3:7, described isolating protein agent adopts hydrogen peroxide, described buffer agent adopts hydroxypropyl methylcellulose, described osmotic pressure regulator adopts lecithin phosphorus phthalate buffer, described chelating agen adopts phosphate.
Embodiment two:
A kind of contact lens disinfection moisturizing liquid medicine, comprise following component and the ratio of each component is: two citric acid monohydrate sodium: 12 parts, boric acid: 25 parts, sorbitol: 25 parts, disodium edetate: 5 parts, sodium chloride: 6 parts, aminomethyl propanol: 15 parts, sodium borate: 4 parts, polybutylene: 8 parts, polyquaternary ammonium salt: 510 parts, myristoyl diemethylamine: 8 parts, wetting agent: 30 parts, isolating protein agent: 15 parts, buffer agent: 10 parts, osmotic pressure regulator: 10 parts, chelating agen: 5 parts, described wetting agent is polyoxyethylene, the mixture of polyoxypropylene, mixed proportion polyoxyethylene: polyoxypropylene is 3:7, described isolating protein agent adopts normal saline, described buffer agent adopts Tai Luoshabai, described osmotic pressure regulator adopts glucose, described chelating agen adopts amino carboxylic acid.
Above-described embodiment is to explanation of the present invention, is not limitation of the invention, anyly all belongs to protection scope of the present invention to the scheme after simple transformation of the present invention.

Claims (8)

1. a contact lens disinfection moisturizing liquid medicine, it is characterized in that: comprise following component and the ratio of each component is: two citric acid monohydrate sodium: 5 parts ~ 12 parts, boric acid: 15 parts ~ 25 parts, sorbitol: 15 parts ~ 25 parts, disodium edetate: 2 parts ~ 5 parts, sodium chloride: 3 parts ~ 6 parts, aminomethyl propanol: 11 parts ~ 15 parts, sodium borate: 2 parts ~ 4 parts, polybutylene: 4 parts ~ 8 parts, polyquaternary ammonium salt: 5 parts ~ 10 parts, myristoyl diemethylamine: 5 parts ~ 8 parts, wetting agent: 15 parts ~ 30 parts, isolating protein agent: 5 parts ~ 15 parts, buffer agent: 5 parts ~ 10 parts, osmotic pressure regulator: 5 parts ~ 10 parts, chelating agen: 2 parts ~ 5 parts.
2. a kind of contact lens disinfection moisturizing liquid medicine as claimed in claim 1, it is characterized in that: described wetting agent is polyoxyethylene, the mixture of bringing up propylene, its mixed proportion is polyoxyethylene: polyoxypropylene is 3:7.
3. a kind of contact lens disinfection moisturizing liquid medicine as claimed in claim 1, is characterized in that: described isolating protein agent adopt in hydrogen peroxide, normal saline, expoxy propane, oxirane any one.
4. a kind of contact lens disinfection moisturizing liquid medicine as claimed in claim 1, is characterized in that: described buffer agent adopt in hydroxypropyl methylcellulose, Tai Luoshabai any one.
5. a kind of contact lens disinfection moisturizing liquid medicine as claimed in claim 1, is characterized in that: described osmotic pressure regulator adopt in lecithin phosphorus phthalate buffer, glucose, sodium sulfate any one.
6. a kind of contact lens disinfection moisturizing liquid medicine as claimed in claim 1, is characterized in that: described chelating agen adopts phosphate, amino carboxylic acid, 1,3-diketone, in hydroxy carboxylic acid, polyamines any one.
7. a kind of contact lens disinfection moisturizing liquid medicine as claimed in claim 1, is characterized in that: two citric acid monohydrate sodium: 6 parts, boric acid: 16 parts, sorbitol: 15 parts, disodium edetate: 3 parts, sodium chloride: 4 parts, aminomethyl propanol: 12 parts, sodium borate: 2 parts, polybutylene: 6 parts, polyquaternary ammonium salt: 6 parts, myristoyl diemethylamine: 8 parts, wetting agent: 18 parts, isolating protein agent: 5 parts, buffer agent: 7 parts, osmotic pressure regulator: 7 parts, chelating agen: 4 parts.
8. a kind of contact lens disinfection moisturizing liquid medicine as claimed in claim 1, is characterized in that: two citric acid monohydrate sodium: 12 parts, boric acid: 25 parts, sorbitol: 25 parts, disodium edetate: 5 parts, sodium chloride: 6 parts, aminomethyl propanol: 15 parts, sodium borate: 4 parts, polybutylene: 8 parts, polyquaternary ammonium salt: 510 parts, myristoyl diemethylamine: 8 parts, wetting agent: 30 parts, isolating protein agent: 15 parts, buffer agent: 10 parts, osmotic pressure regulator: 10 parts, chelating agen: 5 parts.
CN201510359285.2A 2015-06-24 2015-06-24 Contact lens disinfecting and moisturizing medicinal solution Pending CN105031705A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106922723A (en) * 2017-03-03 2017-07-07 海昌隐形眼镜有限公司 A kind of many sterilization system contact lens care solutions of Quaternary Ammonium Salt of Chitosan
US10246819B2 (en) 2016-10-12 2019-04-02 Michael D. Conte Compositions and methods for reversibly dyeing soft contact lenses and medical examination therefrom
CN113088411A (en) * 2021-04-08 2021-07-09 山西利普达医药科技有限公司 Eye washing and inactivating virus composition containing polyquaternium-1 and application thereof
US11891588B2 (en) 2019-07-31 2024-02-06 Ecolab Usa Inc. Personal protective equipment free delimer compositions o

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1186255A (en) * 1996-12-27 1998-07-01 刘伟中 All functional lotion
CN1857301A (en) * 2005-04-30 2006-11-08 上海卫康光学有限公司 Composition for matching with contact lenses and its application
CN101562971A (en) * 2006-05-10 2009-10-21 S.K.药物公司 Synergistically enhanced disinfecting solutions
CN101574537A (en) * 2009-06-01 2009-11-11 海昌隐形眼镜有限公司 Composition for contact lens solution containing peppermint and preparation method thereof
CN103083710A (en) * 2013-01-23 2013-05-08 江苏海伦隐形眼镜有限公司 Corneal contact lens nursing composition containing trehalose quaternary ammonium salt

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1186255A (en) * 1996-12-27 1998-07-01 刘伟中 All functional lotion
CN1857301A (en) * 2005-04-30 2006-11-08 上海卫康光学有限公司 Composition for matching with contact lenses and its application
CN101562971A (en) * 2006-05-10 2009-10-21 S.K.药物公司 Synergistically enhanced disinfecting solutions
CN101574537A (en) * 2009-06-01 2009-11-11 海昌隐形眼镜有限公司 Composition for contact lens solution containing peppermint and preparation method thereof
CN103083710A (en) * 2013-01-23 2013-05-08 江苏海伦隐形眼镜有限公司 Corneal contact lens nursing composition containing trehalose quaternary ammonium salt

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10246819B2 (en) 2016-10-12 2019-04-02 Michael D. Conte Compositions and methods for reversibly dyeing soft contact lenses and medical examination therefrom
CN106922723A (en) * 2017-03-03 2017-07-07 海昌隐形眼镜有限公司 A kind of many sterilization system contact lens care solutions of Quaternary Ammonium Salt of Chitosan
US11891588B2 (en) 2019-07-31 2024-02-06 Ecolab Usa Inc. Personal protective equipment free delimer compositions o
CN113088411A (en) * 2021-04-08 2021-07-09 山西利普达医药科技有限公司 Eye washing and inactivating virus composition containing polyquaternium-1 and application thereof

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