CN105031084A - Traditional Chinese medicine tincture with refreshing effect, and preparation method of traditional Chinese medicine tincture - Google Patents
Traditional Chinese medicine tincture with refreshing effect, and preparation method of traditional Chinese medicine tincture Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine tincture with a refreshing effect, and a preparation method of the traditional Chinese medicine tincture. The traditional Chinese medicine tincture is prepared from the following raw materials in parts by weight: 4-12 parts of codonopsis pilosula 50wt% ethanol water extract, 3-8 parts of flatstem milkvetch seed 50wt% ethanol water extract, 5-10 parts of folium mori 50wt% ethanol water extract, 3-7 parts of burdock ethanol extract, 3-9 parts of pipewort ethanol water extract, 70-100 parts of ethanol, and 140-190 parts of deionized water. The preparation method comprises the following steps: (1) extracting and separating codonopsis pilosula 50wt% ethanol water extract, flatstem milkvetch seed 50wt% ethanol water extract and folium mori 50wt% ethanol water extract; (2) extracting and separating the burdock ethanol extract and the pipewort ethanol water extract; and (3) uniformly stirring the traditional Chinese medicine extracts and the other components according to the weight parts, and thus preparing the traditional Chinese medicine tincture with the refreshing effect.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Traditional Chinese medicine tincture preparation and preparation method thereof, particularly relate to Traditional Chinese medicine tincture preparation of a kind of refreshment and preparation method thereof.
Background technology
Traditional Chinese medicine tincture preparation crude drug is immersed in ethanol or the medicament of shaft medicine dissolution in ethanol, as Semen daturae tincture, Pericarpium Citri junoris tincture, iodine tincture etc., is called for short tincture.Tincture means the supernatant liquid preparation that the ethanol of medicine normal concentration leaches or dissolves and make, and also the dilution of available stream extractum is made, for for oral administration or external.
The Chinese medicine kind of refreshment is more, and such as Folium Camelliae sinensis, Moschus, Borneolum Syntheticum, Styrax, Benzoinum, Camphora, Herba Menthae, Fructus Forsythiae etc. all have certain refreshment effect.Along with the rising of temperature, skin pore is unfolded, and blood supply increases, the corresponding minimizing of oxygen of supply brain.In this case, people can be made to occur downhearted phenomenon, be embodied in the phenomenon of central nervous system impression.Take above-mentioned Chinese medicine, can effectively alleviate above-mentioned problem.Except Chinese medicine, the abnormal smells from the patients such as Fructus Citri Limoniae, Herba Verbenae, Citrus, grapefruit can allow the exuberant vigour of people, have certain stimulating effect.
Summary of the invention
The technical problem solved: the object of the invention is openly a kind ofly have Traditional Chinese medicine tincture preparation of refreshment effect and preparation method thereof, improves Traditional Chinese medicine tincture preparation effect in refreshment, solves the conventional inapparent problem of refreshment Traditional Chinese medicine tincture preparation effect.
Technical scheme: in order to solve the problem, the invention discloses Traditional Chinese medicine tincture preparation of a kind of refreshment and preparation method thereof, and the Traditional Chinese medicine tincture preparation of described refreshment comprises the composition of following weight portion:
Radix Codonopsis 50wt% ethanol-water extraction thing 4-12 part,
Semen Astragali Complanati 50wt% ethanol-water extraction thing 3-8 part,
Folium Mori 50wt% ethanol-water extraction thing 5-10 part,
Fructus Arctii ethanol extraction 3-7 part,
Flos Eriocauli ethanol extraction 3-9 part,
Ethanol 70-100 part,
Deionized water 140-190 part.
Preferably, the Traditional Chinese medicine tincture preparation of described a kind of refreshment, comprises the composition of following weight portion:
Radix Codonopsis 50wt% ethanol-water extraction thing 6-10 part,
Semen Astragali Complanati 50wt% ethanol-water extraction thing 4-7 part,
Folium Mori 50wt% ethanol-water extraction thing 6-9 part,
Fructus Arctii ethanol extraction 4-6 part,
Flos Eriocauli ethanol extraction 4-8 part,
Ethanol 80-90 part,
Deionized water 150-180 part.
The preparation method of the Traditional Chinese medicine tincture preparation of described a kind of refreshment, comprises the following steps:
(1) Radix Codonopsis, Semen Astragali Complanati, Folium Mori are separated vacuum drying, crushed after being dried, lixiviate is carried out again with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:4-1:9, extraction time is 1-4h, and extraction temperature is 45-65 DEG C, centrifugalize after lixiviate, the supernatant is concentrated again, after concentrated, is respectively Radix Codonopsis 50wt% ethanol-water extraction thing, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing;
(2) Fructus Arctii and Flos Eriocauli are pulverized respectively, dry after pulverizing, carry out stirring again with dehydrated alcohol after drying to extract, stirring extraction time is 2-5h, feed liquid weight ratio is 1:6-1:10, Extracting temperature is 40-50 DEG C, and centrifugalize after extracting, obtaining Fructus Arctii ethanol extraction and Flos Eriocauli ethanol extraction after supernatant vacuum concentration;
(3) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 4-12 part, Semen Astragali Complanati 50wt% ethanol-water extraction thing 3-8 part, Folium Mori 50wt% ethanol-water extraction thing 5-10 part, Fructus Arctii ethanol extraction 3-7 part, Flos Eriocauli ethanol extraction 3-9 part, ethanol 70-100 part, deionized water 140-190 part, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
The preparation method of the Traditional Chinese medicine tincture preparation of described a kind of refreshment, in described step (1), lixiviate solid-liquid ratio is 1:7.
The preparation method of the Traditional Chinese medicine tincture preparation of described a kind of refreshment, in described step (1), extraction time is 3h.
The preparation method of the Traditional Chinese medicine tincture preparation of described a kind of refreshment, in described step (1), extraction temperature is 55 DEG C.
The preparation method of the Traditional Chinese medicine tincture preparation of described a kind of refreshment, stirring extraction time in described step (2) is 4h.
The preparation method of the Traditional Chinese medicine tincture preparation of described a kind of refreshment, in described step (2), feed liquid weight ratio is 1:8.
The preparation method of the Traditional Chinese medicine tincture preparation of described a kind of refreshment, in described step (2), Extracting temperature is 45 DEG C.
Beneficial effect: add Chinese medicine extraction elite in Traditional Chinese medicine tincture preparation of the present invention, comprise Radix Codonopsis 50wt% ethanol-water extraction thing 6-10 part, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing, Fructus Arctii ethanol extraction, Flos Eriocauli ethanol extraction.The effect that improve its refreshment that above-mentioned Chinese medicine extraction essential ingredient is common, efficiently solves conventional Traditional Chinese medicine tincture preparation Chinese medicine essential ingredient wherein on refreshment, acts on unconspicuous problem.
Detailed description of the invention
Embodiment 1
(1) Radix Codonopsis, Semen Astragali Complanati, Folium Mori are separated vacuum drying, crushed after being dried, lixiviate is carried out again with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:9, extraction time is 1h, and extraction temperature is 65 DEG C, centrifugalize after lixiviate, the supernatant is concentrated again, after concentrated, is respectively Radix Codonopsis 50wt% ethanol-water extraction thing, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing; (2) Fructus Arctii and Flos Eriocauli are pulverized respectively, dry after pulverizing, carry out stirring again with dehydrated alcohol after drying to extract, stirring extraction time is 5h, feed liquid weight ratio is 1:6, Extracting temperature is 40 DEG C, and centrifugalize after extracting, obtaining Fructus Arctii ethanol extraction and Flos Eriocauli ethanol extraction after supernatant vacuum concentration; (3) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 12 parts, Semen Astragali Complanati 50wt% ethanol-water extraction thing 3 parts, Folium Mori 50wt% ethanol-water extraction thing 5 parts, Fructus Arctii ethanol extraction 7 parts, Flos Eriocauli ethanol extraction 9 parts, ethanol 100 parts, deionized water 190 parts, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
Traditional Chinese medicine tincture preparation effect on refreshment of embodiment 1 is better, and refreshment effect is better, and retention time is longer.
Embodiment 2
(1) Radix Codonopsis, Semen Astragali Complanati, Folium Mori are separated vacuum drying, crushed after being dried, lixiviate is carried out again with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:4, extraction time is 4h, and extraction temperature is 45 DEG C, centrifugalize after lixiviate, the supernatant is concentrated again, after concentrated, is respectively Radix Codonopsis 50wt% ethanol-water extraction thing, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing; (2) Fructus Arctii and Flos Eriocauli are pulverized respectively, dry after pulverizing, carry out stirring again with dehydrated alcohol after drying to extract, stirring extraction time is 2h, feed liquid weight ratio is 1:10, Extracting temperature is 50 DEG C, and centrifugalize after extracting, obtaining Fructus Arctii ethanol extraction and Flos Eriocauli ethanol extraction after supernatant vacuum concentration; (3) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 4 parts, Semen Astragali Complanati 50wt% ethanol-water extraction thing 8 parts, Folium Mori 50wt% ethanol-water extraction thing 10 parts, Fructus Arctii ethanol extraction 3 parts, Flos Eriocauli ethanol extraction 3 parts, ethanol 70 parts, deionized water 140 parts, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
Traditional Chinese medicine tincture preparation effect on refreshment of embodiment 2 is better, and refreshment effect is better, and retention time is longer.
Embodiment 3
(1) Radix Codonopsis, Semen Astragali Complanati, Folium Mori are separated vacuum drying, crushed after being dried, lixiviate is carried out again with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:9, extraction time is 1h, and extraction temperature is 65 DEG C, centrifugalize after lixiviate, the supernatant is concentrated again, after concentrated, is respectively Radix Codonopsis 50wt% ethanol-water extraction thing, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing; (2) Fructus Arctii and Flos Eriocauli are pulverized respectively, dry after pulverizing, carry out stirring again with dehydrated alcohol after drying to extract, stirring extraction time is 5h, feed liquid weight ratio is 1:6, Extracting temperature is 40 DEG C, and centrifugalize after extracting, obtaining Fructus Arctii ethanol extraction and Flos Eriocauli ethanol extraction after supernatant vacuum concentration; (3) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 10 parts, Semen Astragali Complanati 50wt% ethanol-water extraction thing 7 parts, Folium Mori 50wt% ethanol-water extraction thing 6 parts, Fructus Arctii ethanol extraction 6 parts, Flos Eriocauli ethanol extraction 4 parts, ethanol 80 parts, deionized water 150 parts, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
Traditional Chinese medicine tincture preparation effect on refreshment of embodiment 3 is fine, and refreshment effect is fine, and retention time is very long.
Embodiment 4
(1) Radix Codonopsis, Semen Astragali Complanati, Folium Mori are separated vacuum drying, crushed after being dried, lixiviate is carried out again with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:4, extraction time is 4h, and extraction temperature is 45 DEG C, centrifugalize after lixiviate, the supernatant is concentrated again, after concentrated, is respectively Radix Codonopsis 50wt% ethanol-water extraction thing, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing; (2) Fructus Arctii and Flos Eriocauli are pulverized respectively, dry after pulverizing, carry out stirring again with dehydrated alcohol after drying to extract, stirring extraction time is 2h, feed liquid weight ratio is 1:10, Extracting temperature is 50 DEG C, and centrifugalize after extracting, obtaining Fructus Arctii ethanol extraction and Flos Eriocauli ethanol extraction after supernatant vacuum concentration; (3) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 6 parts, Semen Astragali Complanati 50wt% ethanol-water extraction thing 4 parts, Folium Mori 50wt% ethanol-water extraction thing 9 parts, Fructus Arctii ethanol extraction 4 parts, Flos Eriocauli ethanol extraction 8 parts, ethanol 90 parts, deionized water 180 parts, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
Traditional Chinese medicine tincture preparation effect on refreshment of embodiment 4 is fine, and refreshment effect is fine, and retention time is very long.
Embodiment 5
(1) Radix Codonopsis, Semen Astragali Complanati, Folium Mori are separated vacuum drying, crushed after being dried, lixiviate is carried out again with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:7, extraction time is 3h, and extraction temperature is 55 DEG C, centrifugalize after lixiviate, the supernatant is concentrated again, after concentrated, is respectively Radix Codonopsis 50wt% ethanol-water extraction thing, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing; (2) Fructus Arctii and Flos Eriocauli are pulverized respectively, dry after pulverizing, carry out stirring again with dehydrated alcohol after drying to extract, stirring extraction time is 4h, feed liquid weight ratio is 1:8, Extracting temperature is 45 DEG C, and centrifugalize after extracting, obtaining Fructus Arctii ethanol extraction and Flos Eriocauli ethanol extraction after supernatant vacuum concentration; (3) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 8 parts, Semen Astragali Complanati 50wt% ethanol-water extraction thing 6 parts, Folium Mori 50wt% ethanol-water extraction thing 7 parts, Fructus Arctii ethanol extraction 5 parts, Flos Eriocauli ethanol extraction 6 parts, ethanol 85 parts, deionized water 165 parts, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
Traditional Chinese medicine tincture preparation effect on refreshment of embodiment 5 is very good, and refreshment effect highly significant, retention time is very long.
Comparative example 1
(1) Radix Codonopsis, Semen Astragali Complanati, Folium Mori are separated vacuum drying, crushed after being dried, lixiviate is carried out again with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:4, extraction time is 4h, and extraction temperature is 45 DEG C, centrifugalize after lixiviate, the supernatant is concentrated again, after concentrated, is respectively Radix Codonopsis 50wt% ethanol-water extraction thing, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing; (2) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 4 parts, Semen Astragali Complanati 50wt% ethanol-water extraction thing 8 parts, Folium Mori 50wt% ethanol-water extraction thing 10 parts, ethanol 70 parts, deionized water 140 parts, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
Traditional Chinese medicine tincture preparation effect on refreshment of comparative example 1 is common, has certain refreshment effect.
Comparative example 2
(1) by Radix Codonopsis vacuum drying, crushed after being dried, then carry out lixiviate with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:4, and extraction time is 4h, and extraction temperature is 45 DEG C, centrifugalize after lixiviate, concentrates the supernatant again, is Radix Codonopsis 50wt% ethanol-water extraction thing after concentrated; (2) Fructus Arctii and Flos Eriocauli are pulverized respectively, dry after pulverizing, carry out stirring again with dehydrated alcohol after drying to extract, stirring extraction time is 2h, feed liquid weight ratio is 1:10, Extracting temperature is 50 DEG C, and centrifugalize after extracting, obtaining Fructus Arctii ethanol extraction and Flos Eriocauli ethanol extraction after supernatant vacuum concentration; (3) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 4 parts, Fructus Arctii ethanol extraction 3 parts, Flos Eriocauli ethanol extraction 3 parts, ethanol 70 parts, deionized water 140 parts, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
Traditional Chinese medicine tincture preparation effect on refreshment of comparative example 2 is general, has certain refreshment effect.
Claims (9)
1. a Traditional Chinese medicine tincture preparation for refreshment, is characterized in that, the Traditional Chinese medicine tincture preparation of described refreshment comprises the composition of following weight portion:
Radix Codonopsis 50wt% ethanol-water extraction thing 4-12 part,
Semen Astragali Complanati 50wt% ethanol-water extraction thing 3-8 part,
Folium Mori 50wt% ethanol-water extraction thing 5-10 part,
Fructus Arctii ethanol extraction 3-7 part,
Flos Eriocauli ethanol extraction 3-9 part,
Ethanol 70-100 part,
Deionized water 140-190 part.
2. the Traditional Chinese medicine tincture preparation of a kind of refreshment according to claim 1, is characterized in that, the Traditional Chinese medicine tincture preparation of described refreshment comprises the composition of following weight portion:
Radix Codonopsis 50wt% ethanol-water extraction thing 6-10 part,
Semen Astragali Complanati 50wt% ethanol-water extraction thing 4-7 part,
Folium Mori 50wt% ethanol-water extraction thing 6-9 part,
Fructus Arctii ethanol extraction 4-6 part,
Flos Eriocauli ethanol extraction 4-8 part,
Ethanol 80-90 part,
Deionized water 150-180 part.
3. the preparation method of the Traditional Chinese medicine tincture preparation of a kind of refreshment according to claim 1, is characterized in that, described preparation method comprises the following steps:
(1) Radix Codonopsis, Semen Astragali Complanati, Folium Mori are separated vacuum drying, crushed after being dried, lixiviate is carried out again with 50wt% ethanol water, lixiviate solid-liquid ratio is 1:4-1:9, extraction time is 1-4h, and extraction temperature is 45-65 DEG C, centrifugalize after lixiviate, the supernatant is concentrated again, after concentrated, is respectively Radix Codonopsis 50wt% ethanol-water extraction thing, Semen Astragali Complanati 50wt% ethanol-water extraction thing, Folium Mori 50wt% ethanol-water extraction thing;
(2) Fructus Arctii and Flos Eriocauli are pulverized respectively, dry after pulverizing, carry out stirring again with dehydrated alcohol after drying to extract, stirring extraction time is 2-5h, feed liquid weight ratio is 1:6-1:10, Extracting temperature is 40-50 DEG C, and centrifugalize after extracting, obtaining Fructus Arctii ethanol extraction and Flos Eriocauli ethanol extraction after supernatant vacuum concentration;
(3) by weight respectively by Radix Codonopsis 50wt% ethanol-water extraction thing 4-12 part, Semen Astragali Complanati 50wt% ethanol-water extraction thing 3-8 part, Folium Mori 50wt% ethanol-water extraction thing 5-10 part, Fructus Arctii ethanol extraction 3-7 part, Flos Eriocauli ethanol extraction 3-9 part, ethanol 70-100 part, deionized water 140-190 part, being stirred to evenly, is the Traditional Chinese medicine tincture preparation of refreshment.
4. the preparation method of the Traditional Chinese medicine tincture preparation of a kind of refreshment according to claim 3, is characterized in that, in described step (1), lixiviate solid-liquid ratio is 1:7.
5. the preparation method of the Traditional Chinese medicine tincture preparation of a kind of refreshment according to claim 3, is characterized in that, in described step (1), extraction time is 3h.
6. the preparation method of the Traditional Chinese medicine tincture preparation of a kind of refreshment according to claim 3, is characterized in that, in described step (1), extraction temperature is 55 DEG C.
7. the preparation method of the Traditional Chinese medicine tincture preparation of a kind of refreshment according to claim 3, is characterized in that, stirring extraction time in described step (2) is 4h.
8. the preparation method of the Traditional Chinese medicine tincture preparation of a kind of refreshment according to claim 3, is characterized in that, in described step (2), feed liquid weight ratio is 1:8.
9. the preparation method of the Traditional Chinese medicine tincture preparation of a kind of refreshment according to claim 3, is characterized in that, in described step (2), Extracting temperature is 45 DEG C.
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CN101380420A (en) * | 2008-10-10 | 2009-03-11 | 孙继红 | Mental-refreshing and brain-awaking injection and production technique thereof |
CN102293276A (en) * | 2011-09-22 | 2011-12-28 | 王璐 | Liver-clearing vision-improving health-care tea |
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CN101380420A (en) * | 2008-10-10 | 2009-03-11 | 孙继红 | Mental-refreshing and brain-awaking injection and production technique thereof |
CN102293276A (en) * | 2011-09-22 | 2011-12-28 | 王璐 | Liver-clearing vision-improving health-care tea |
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