CN105025918A - 利尿钠肽、利尿肽或血管舒张肽用于治疗心血管适应症的方法 - Google Patents

利尿钠肽、利尿肽或血管舒张肽用于治疗心血管适应症的方法 Download PDF

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Publication number
CN105025918A
CN105025918A CN201480013163.1A CN201480013163A CN105025918A CN 105025918 A CN105025918 A CN 105025918A CN 201480013163 A CN201480013163 A CN 201480013163A CN 105025918 A CN105025918 A CN 105025918A
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CN
China
Prior art keywords
hours
peptide
methods according
natriuretic peptide
patient
Prior art date
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Pending
Application number
CN201480013163.1A
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English (en)
Chinese (zh)
Inventor
J·霍尔茨迈斯特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CARDIORENTIS Ltd
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CARDIORENTIS Ltd
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Publication of CN105025918A publication Critical patent/CN105025918A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2242Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2221Relaxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Dermatology (AREA)
CN201480013163.1A 2013-01-25 2014-01-24 利尿钠肽、利尿肽或血管舒张肽用于治疗心血管适应症的方法 Pending CN105025918A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361756692P 2013-01-25 2013-01-25
US61/756,692 2013-01-25
PCT/IB2014/000253 WO2014115033A2 (en) 2013-01-25 2014-01-24 Methods of treating cardiovascular indications

Publications (1)

Publication Number Publication Date
CN105025918A true CN105025918A (zh) 2015-11-04

Family

ID=50382492

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480013163.1A Pending CN105025918A (zh) 2013-01-25 2014-01-24 利尿钠肽、利尿肽或血管舒张肽用于治疗心血管适应症的方法

Country Status (19)

Country Link
US (2) US20140213520A1 (https=)
EP (1) EP2948165A2 (https=)
JP (1) JP2016505065A (https=)
KR (1) KR20150108903A (https=)
CN (1) CN105025918A (https=)
AP (1) AP2015008624A0 (https=)
AU (1) AU2014208851B2 (https=)
BR (1) BR112015017432A2 (https=)
CA (1) CA2898571A1 (https=)
DO (1) DOP2015000175A (https=)
EA (1) EA201500765A1 (https=)
IL (1) IL239909A0 (https=)
MX (1) MX2015009606A (https=)
NZ (1) NZ710246A (https=)
PH (1) PH12015501559A1 (https=)
SG (1) SG11201505492XA (https=)
TN (1) TN2015000315A1 (https=)
TW (1) TW201442722A (https=)
WO (1) WO2014115033A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105617360A (zh) * 2015-12-04 2016-06-01 中国农业大学 C-型钠肽在制备外用避孕药和精子功能检测试剂中的应用
CN110278941A (zh) * 2019-07-11 2019-09-27 西安国际医学中心有限公司 一种含有钠尿肽的离体心脏保护液

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015184248A1 (en) * 2014-05-30 2015-12-03 Concert Pharmaceuticals, Inc. Methods of treating fibrotic diseases
EP4035659A1 (en) 2016-11-29 2022-08-03 PureTech LYT, Inc. Exosomes for delivery of therapeutic agents

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006110743A1 (en) * 2005-04-07 2006-10-19 Cardiopep Pharma Gmbh Use of natriuretic peptide for treating heart failure
WO2009086126A2 (en) * 2007-12-21 2009-07-09 Mayo Foundation For Medical Education And Research Natriuretic polypeptides

Family Cites Families (20)

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DE3346953A1 (de) 1983-12-24 1985-08-14 Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft mbH, 6900 Heidelberg Cardiodilatin, ein neues peptidhormon und verfahren zu seiner herstellung
US5449751A (en) 1987-03-02 1995-09-12 Pharma Bissendorf Peptide Gmbh Cardiodilatin fragment, process for preparing same and use thereof
US5461142A (en) 1987-11-07 1995-10-24 Pharma Bissendorf Peptide Gmbh Phosphorylated derivatives of cardiodilatin/ANF peptides
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy
DE4216133A1 (de) 1992-05-15 1993-11-18 Bissendorf Peptide Gmbh Anwendung von Urodilatin bei Lungen- und Bronchialerkrankungen
WO1995033769A1 (de) 1994-06-02 1995-12-14 Boehringer Mannheim Gmbh Verfahren zur herstellung von cardiodilatin-fragmenten, hochgereinigte cardiodilatin-fragmente und zwischenprodukte zu deren herstellung
DE19951471A1 (de) 1999-10-26 2001-05-03 Forssmann Wolf Georg Verwendung von Urodilatin zur Behandlung chronischer Niereninsuffizienz mit Nierenrestfunktionen
US6407211B1 (en) * 1999-12-17 2002-06-18 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides
CA2425712C (en) * 2000-10-04 2017-06-06 Molecular Medicine Research Institute Methods of modulating apoptosis by administration of relaxin agonists or antagonists
KR101271635B1 (ko) * 2001-12-21 2013-06-12 휴먼 게놈 사이언시즈, 인코포레이티드 알부민 융합 단백질
US20050113286A1 (en) * 2002-03-18 2005-05-26 Schreiner George F. Methods for treating congestive heart failure
US8293711B2 (en) * 2007-09-11 2012-10-23 Pharis Biotech Gmbh Use of natriuretic peptides for treating angioedema syndromes
JP2011520917A (ja) * 2008-05-16 2011-07-21 コーセラ,インコーポレーテッド 慢性心不全の治療方法
US8642550B2 (en) * 2008-10-24 2014-02-04 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides without hypotensive inducing capability
JP2010116325A (ja) * 2008-11-11 2010-05-27 Institute For Protein Science Co Ltd Sirs患者を救命するためのペプチド組成物
US20110014180A1 (en) * 2009-07-16 2011-01-20 Masafumi Koide Preparations for tissue restoration containing atrial diuretic hormone and family molecules as active ingredients; method of restoring tissue using the preparation; agents for growing, restoring, promoting growth of hair and agents for promoting restoration of skin tissue and cardiac muscle tissue containing atrial diuretic hormone family molecules as active ingredients; method of growing, restoring, promoting growth of hair by using the agents; and method of promoting restoration of skin tissue and cardiac muscle tissue
EP2480247B1 (en) * 2009-09-25 2020-02-12 Shire Orphan Therapies GmbH Novel npr-b agonists
US8551938B2 (en) * 2009-09-25 2013-10-08 Alcon Research, Ltd. NPR-B agonists
WO2011113825A1 (en) * 2010-03-15 2011-09-22 Wolf-Georg Forssmann Use of urodilatin for preparing a medicament for the treatment of cardiovascular, renal, pulmonary and neuronal syndromes while avoiding a rebound
BR112013003823A2 (pt) * 2010-08-20 2016-06-28 Cerulean Pharma Inc conjugados de peptídeo terapêutico-políemro, partículas, composições, e métodos relacionados

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006110743A1 (en) * 2005-04-07 2006-10-19 Cardiopep Pharma Gmbh Use of natriuretic peptide for treating heart failure
US20060264376A1 (en) * 2005-04-07 2006-11-23 Cardiopep Pharma Gmbh Use of natriuretic peptide for treating heart failure
WO2009086126A2 (en) * 2007-12-21 2009-07-09 Mayo Foundation For Medical Education And Research Natriuretic polypeptides

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105617360A (zh) * 2015-12-04 2016-06-01 中国农业大学 C-型钠肽在制备外用避孕药和精子功能检测试剂中的应用
WO2017092178A1 (zh) * 2015-12-04 2017-06-08 中国农业大学 C-型钠肽在制备外用避孕药和精子功能检测中的应用
CN110278941A (zh) * 2019-07-11 2019-09-27 西安国际医学中心有限公司 一种含有钠尿肽的离体心脏保护液

Also Published As

Publication number Publication date
TW201442722A (zh) 2014-11-16
AU2014208851B2 (en) 2016-12-22
IL239909A0 (en) 2015-08-31
WO2014115033A2 (en) 2014-07-31
BR112015017432A2 (pt) 2017-07-11
SG11201505492XA (en) 2015-08-28
AU2014208851A1 (en) 2015-08-06
PH12015501559A1 (en) 2015-09-21
KR20150108903A (ko) 2015-09-30
AP2015008624A0 (en) 2015-07-31
DOP2015000175A (es) 2015-11-15
WO2014115033A3 (en) 2015-02-26
EA201500765A1 (ru) 2015-12-30
US20140213520A1 (en) 2014-07-31
US20140213519A1 (en) 2014-07-31
CA2898571A1 (en) 2014-07-31
EP2948165A2 (en) 2015-12-02
NZ710246A (en) 2016-11-25
MX2015009606A (es) 2016-04-26
JP2016505065A (ja) 2016-02-18
TN2015000315A1 (en) 2017-01-03

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